Hypoxia-Inducible Factor 1, alpha Subunit
"Hypoxia-Inducible Factor 1, alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
| Descriptor ID |
D051795
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| MeSH Number(s) |
D12.776.260.103.625.750 D12.776.930.125.625.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1, alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1, alpha Subunit".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in this website by year, and whether "Hypoxia-Inducible Factor 1, alpha Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 5 | 2 | 7 |
| 2008 | 4 | 0 | 4 |
| 2009 | 2 | 2 | 4 |
| 2010 | 2 | 5 | 7 |
| 2011 | 2 | 6 | 8 |
| 2012 | 8 | 3 | 11 |
| 2013 | 3 | 6 | 9 |
| 2014 | 3 | 2 | 5 |
| 2015 | 4 | 2 | 6 |
| 2016 | 4 | 1 | 5 |
| 2017 | 2 | 3 | 5 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in Profiles.
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Dogan E, Galifi CA, Cecen B, Shukla R, Wood TL, Miri AK. Extracellular matrix regulation of cell spheroid invasion in a 3D bioprinted solid tumor-on-a-chip. Acta Biomater. 2024 09 15; 186:156-166.
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Langbein LE, El Hajjar R, He S, Sementino E, Zhong Z, Jiang W, Leiby BE, Li L, Uzzo RG, Testa JR, Yang H. BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma. Cancer Lett. 2022 10 28; 547:215885.
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Sharma AL, Wang H, Zhang Z, Millien G, Tyagi M, Hongpaisan J. HIV Promotes Neurocognitive Impairment by Damaging the Hippocampal Microvessels. Mol Neurobiol. 2022 Aug; 59(8):4966-4986.
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Garchow B, Maque Acosta Y, Kiriakidou M. HIF-1a and miR-210 differential and lineage-specific expression in systemic lupus erythematosus. Mol Immunol. 2021 05; 133:128-134.
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Novais EJ, Choi H, Madhu V, Suyama K, Anjo SI, Manadas B, Shapiro IM, Salgado AJ, Risbud MV. Hypoxia and Hypoxia-Inducible Factor-1a Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion. Am J Pathol. 2021 03; 191(3):487-502.
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Madhu V, Boneski PK, Silagi E, Qiu Y, Kurland I, Guntur AR, Shapiro IM, Risbud MV. Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1a-BNIP3 Axis. J Bone Miner Res. 2020 08; 35(8):1504-1524.
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Silagi ES, Novais EJ, Bisetto S, Telonis AG, Snuggs J, Le Maitre CL, Qiu Y, Kurland IJ, Shapiro IM, Philp NJ, Risbud MV. Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health. J Bone Miner Res. 2020 03; 35(3):550-570.
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Chen Z, Lin TC, Bi X, Lu G, Dawson BC, Miranda R, Medeiros LJ, McNiece I, McCarty N. TRIM44 promotes quiescent multiple myeloma cell occupancy and survival in the osteoblastic niche via HIF-1a stabilization. Leukemia. 2019 02; 33(2):469-486.
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Pan H, Strickland A, Madhu V, Johnson ZI, Chand SN, Brody JR, Fertala A, Zheng Z, Shapiro IM, Risbud MV. RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1a signaling in nucleus pulposus cells. Matrix Biol. 2019 04; 77:23-40.
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Silagi ES, Batista P, Shapiro IM, Risbud MV. Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death. Sci Rep. 2018 03 20; 8(1):4856.