Receptors, TNF-Related Apoptosis-Inducing Ligand
"Receptors, TNF-Related Apoptosis-Inducing Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor necrosis factor receptor family members that are widely expressed and play a role in regulation of peripheral immune responses and APOPTOSIS. The receptors are specific for TNF-RELATED APOPTOSIS-INDUCING LIGAND and signal via conserved DEATH DOMAINS that associate with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
| Descriptor ID |
D053220
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| MeSH Number(s) |
D12.776.543.750.690.600 D12.776.543.750.705.852.760.396
|
| Concept/Terms |
Receptors, TNF-Related Apoptosis-Inducing Ligand- Receptors, TNF-Related Apoptosis-Inducing Ligand
- Receptors, TNF Related Apoptosis Inducing Ligand
- Tumor Necrosis Factor Receptor Superfamily, Member 10
- TRAIL Receptors
- Receptors, TRAIL
- Receptors, Tumor Necrosis Factor, Member 10
- TNF-Related Apoptosis-Inducing Ligand Receptors
- TNF Related Apoptosis Inducing Ligand Receptors
Receptors, Tumor Necrosis Factor, Member 10d- Receptors, Tumor Necrosis Factor, Member 10d
- Decoy Receptor 2, Tumor Necrosis Factor
- Receptor, TRAIL-4
- Receptor, TRAIL 4
- TRAIL-4 Receptor
- DCR2 Receptor
- Receptor, DCR2
- CD264 Antigen
- Antigen, CD264
- TRAIL Receptor 4
- Receptor 4, TRAIL
Receptors, Tumor Necrosis Factor, Member 10a- Receptors, Tumor Necrosis Factor, Member 10a
- Tumor Necrosis Factor Receptor Superfamily, Member 10a
- APO2 Receptor
- Receptor, APO2
- Receptor, TRAIL-1
- Receptor, TRAIL 1
- TRAIL-1 Receptor
- TRAIL Receptor 1
- DR4 Receptor
- Receptor, DR4
- CD261 Antigen
- Antigen, CD261
- Death Receptor-4
- Death Receptor 4
- Receptor-4, Death
Receptors, Tumor Necrosis Factor, Member 10b- Receptors, Tumor Necrosis Factor, Member 10b
- TRAIL Receptor 2
- Receptor, TRAIL-2
- Receptor, TRAIL 2
- TRAIL-2 Receptor
- DR5 Receptor
- Receptor, DR5
- Tumor Necrosis Factor Receptor Superfamily, Member 10b
- TNF-Related Apoptosis-Inducing Ligand Receptor 2
- TNF Related Apoptosis Inducing Ligand Receptor 2
- CD262 Antigen
- Antigen, CD262
- Death Receptor-5
- Death Receptor 5
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Below are MeSH descriptors whose meaning is more general than "Receptors, TNF-Related Apoptosis-Inducing Ligand".
Below are MeSH descriptors whose meaning is more specific than "Receptors, TNF-Related Apoptosis-Inducing Ligand".
This graph shows the total number of publications written about "Receptors, TNF-Related Apoptosis-Inducing Ligand" by people in this website by year, and whether "Receptors, TNF-Related Apoptosis-Inducing Ligand" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, TNF-Related Apoptosis-Inducing Ligand" by people in Profiles.
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Sharma S, de Vries EG, Infante JR, Oldenhuis CN, Gietema JA, Yang L, Bilic S, Parker K, Goldbrunner M, Scott JW, Burris HA. Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors. Invest New Drugs. 2014 Feb; 32(1):135-44.
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Valley CC, Lewis AK, Mudaliar DJ, Perlmutter JD, Braun AR, Karim CB, Thomas DD, Brody JR, Sachs JN. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized. J Biol Chem. 2012 Jun 15; 287(25):21265-78.
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Robertson NM, Zangrilli JG, Steplewski A, Hastie A, Lindemeyer RG, Planeta MA, Smith MK, Innocent N, Musani A, Pascual R, Peters S, Litwack G. Differential expression of TRAIL and TRAIL receptors in allergic asthmatics following segmental antigen challenge: evidence for a role of TRAIL in eosinophil survival. J Immunol. 2002 Nov 15; 169(10):5986-96.
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Wu GS, Burns TF, Zhan Y, Alnemri ES, El-Deiry WS. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Cancer Res. 1999 Jun 15; 59(12):2770-5.
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MacFarlane M, Ahmad M, Srinivasula SM, Fernandes-Alnemri T, Cohen GM, Alnemri ES. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J Biol Chem. 1997 Oct 10; 272(41):25417-20.