"Chromogranin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.
| Descriptor ID |
D053379
|
| MeSH Number(s) |
D12.776.631.199.249
|
| Concept/Terms |
Chromogranin A- Chromogranin A
- Parathyroid Secretory Protein
- Secretory Protein, Parathyroid
- CHGA Protein
- Secretory Protein I, Parathyroid Gland
|
Below are MeSH descriptors whose meaning is more general than "Chromogranin A".
Below are MeSH descriptors whose meaning is more specific than "Chromogranin A".
This graph shows the total number of publications written about "Chromogranin A" by people in this website by year, and whether "Chromogranin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chromogranin A" by people in Profiles.
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Zhang T, Ahn K, Emerick B, Modarai SR, Opdenaker LM, Palazzo J, Schleiniger G, Fields JZ, Boman BM. APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development. PLoS One. 2020; 15(10):e0239601.
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Ohsie S, Gerney G, Gui D, Kahana D, Martín MG, Cortina G. A paucity of colonic enteroendocrine and/or enterochromaffin cells characterizes a subset of patients with chronic unexplained diarrhea/malabsorption. Hum Pathol. 2009 Jul; 40(7):1006-14.
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Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H. Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors. Ann Surg Oncol. 2009 Feb; 16(2):481-6.