"Keratin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type II keratin that is found associated with the KERATIN-14 in the internal stratified EPITHELIUM. Mutations in the gene for keratin-5 are associated with EPIDERMOLYSIS BULLOSA SIMPLEX.
| Descriptor ID |
D053555
|
| MeSH Number(s) |
D05.750.078.593.450.600.500 D12.776.220.475.450.600.500 D12.776.860.607.650.500
|
| Concept/Terms |
Keratin-5- Keratin-5
- Keratin 5
- Cytokeratin-5
- Cytokeratin 5
|
Below are MeSH descriptors whose meaning is more general than "Keratin-5".
Below are MeSH descriptors whose meaning is more specific than "Keratin-5".
This graph shows the total number of publications written about "Keratin-5" by people in this website by year, and whether "Keratin-5" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Keratin-5" by people in Profiles.
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Barzegar M, Asadi-Kani Z, Mozafari N, Vahidnezhad H, Kariminejad A, Toossi P. Using immunofluorescence (antigen) mapping in the diagnosis and classification of epidermolysis bullosa: a first report from Iran. Int J Dermatol. 2015 Oct; 54(10):e416-23.
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Trufant JW, Kreizenbeck GM, Carlson KR, Muthusamy V, Girardi M, Bosenberg MW. A transient epidermolysis bullosa simplex-like phenotype associated with bexarotene treatment in a G138E KRT5 heterozygote. J Cutan Pathol. 2010 Nov; 37(11):1155-60.
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Witkiewicz AK, Dasgupta A, Sammons S, Er O, Potoczek MB, Guiles F, Sotgia F, Brody JR, Mitchell EP, Lisanti MP. Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers. Cancer Biol Ther. 2010 Jul; 10(2):135-43.
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Pfendner EG, Sadowski SG, Uitto J. Epidermolysis bullosa simplex: recurrent and de novo mutations in the KRT5 and KRT14 genes, phenotype/genotype correlations, and implications for genetic counseling and prenatal diagnosis. J Invest Dermatol. 2005 Aug; 125(2):239-43.
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Ciubotaru D, Bergman R, Baty D, Indelman M, Pfendner E, Petronius D, Moualem H, Kanaan M, Ben Amitai D, McLean WH, Uitto J, Sprecher E. Epidermolysis bullosa simplex in Israel: clinical and genetic features. Arch Dermatol. 2003 Apr; 139(4):498-505.
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Sprecher E, Yosipovitch G, Bergman R, Ciubutaro D, Indelman M, Pfendner E, Goh LC, Miller CJ, Uitto J, Richard G. Epidermolytic hyperkeratosis and epidermolysis bullosa simplex caused by frameshift mutations altering the v2 tail domains of keratin 1 and keratin 5. J Invest Dermatol. 2003 Apr; 120(4):623-6.