"Interleukin-1alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
| Descriptor ID |
D053582
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| MeSH Number(s) |
D12.644.276.374.465.010.300 D12.644.276.374.500.400.300 D12.776.467.374.465.010.300 D12.776.467.374.500.400.300 D23.529.374.465.131.300 D23.529.374.500.400.300
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| Concept/Terms |
Interleukin-1alpha- Interleukin-1alpha
- Interleukin 1alpha
- IL-1 alpha
- Interleukin-1 alpha
- Interleukin 1 alpha
- Hematopoietin-1
- Hematopoietin 1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-1alpha".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1alpha".
This graph shows the total number of publications written about "Interleukin-1alpha" by people in this website by year, and whether "Interleukin-1alpha" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Interleukin-1alpha" by people in Profiles.
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Assayag E, Gurt I, Cohen-Kfir E, Stokar J, Zwas DR, Dresner-Pollak R. Cardiac Left Ventricular miRNA-26a Is Downregulated in Ovariectomized Mice, Upregulated upon 17-Beta Estradiol Replacement, and Inversely Correlated with Collagen Type 1 Gene Expression. Int J Mol Sci. 2024 May 09; 25(10).
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Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Recruitment of pro-IL-1a to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation. Proc Natl Acad Sci U S A. 2021 01 05; 118(1).
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Sorrentino R, Terlizzi M, Di Crescenzo VG, Popolo A, Pecoraro M, Perillo G, Galderisi A, Pinto A. Human lung cancer-derived immunosuppressive plasmacytoid dendritic cells release IL-1a in an AIM2 inflammasome-dependent manner. Am J Pathol. 2015 Nov; 185(11):3115-24.
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Deirmengian C, Kardos K, Kilmartin P, Cameron A, Schiller K, Parvizi J. Diagnosing periprosthetic joint infection: has the era of the biomarker arrived? Clin Orthop Relat Res. 2014 Nov; 472(11):3254-62.
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Dutcher JP, Neuberg D, Atkins MB, Tester WJ, Wadler S, Stewart JA, Chachoua A, Schuchter LM. Report of a phase I evaluation of dose and schedule of interleukin-1 alpha and cyclophosphamide in patients with advanced tumors: An Eastern Cooperative Oncology Group study (PX990) and review of IL-1-based studies of hematopoietic reconstitution. J Interferon Cytokine Res. 2014 May; 34(5):376-84.
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Goteiner D, Ashmen R, Lehrman N, Janal MN, Eskin B. Presence and significance of interleukin-1 polymorphism in patients who present with acute coronary syndrome, angina, and chronic periodontitis: an epidemiologic pilot study. J Periodontol. 2008 Jan; 79(1):138-43.