"Syndecan-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed syndecan that is found in all stages of embryonic development and in most adult tissues. Syndecan-4 is found localized to focal adhesion sites in fibronectin-adherent cells and may play a role the process of CELL MIGRATION and CELL PROLIFERATION.
| Descriptor ID |
D053671
|
| MeSH Number(s) |
D12.776.395.550.847.800 D12.776.395.650.350.500.800 D12.776.543.550.847.400
|
| Concept/Terms |
Syndecan-4- Syndecan-4
- Ryudocan
- Syndecan 4
- Syndecan4
- Amphiglycan
- Ryudocan Core Protein
|
Below are MeSH descriptors whose meaning is more general than "Syndecan-4".
Below are MeSH descriptors whose meaning is more specific than "Syndecan-4".
This graph shows the total number of publications written about "Syndecan-4" by people in this website by year, and whether "Syndecan-4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Syndecan-4" by people in Profiles.
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Sao K, Risbud MV. Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine. Matrix Biol. 2024 Aug; 131:46-61.
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Brusilovsky M, Radinsky O, Cohen L, Yossef R, Shemesh A, Braiman A, Mandelboim O, Campbell KS, Porgador A. Regulation of natural cytotoxicity receptors by heparan sulfate proteoglycans in -cis: A lesson from NKp44. Eur J Immunol. 2015 Apr; 45(4):1180-91.
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Brusilovsky M, Cordoba M, Rosental B, Hershkovitz O, Andrake MD, Pecherskaya A, Einarson MB, Zhou Y, Braiman A, Campbell KS, Porgador A. Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses. J Immunol. 2013 Nov 15; 191(10):5256-67.
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Wang J, Markova D, Anderson DG, Zheng Z, Shapiro IM, Risbud MV. TNF-a and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc. J Biol Chem. 2011 Nov 18; 286(46):39738-49.
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Cevikbas F, Schaefer L, Uhlig P, Robenek H, Theilmeier G, Echtermeyer F, Bruckner P. Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice. Matrix Biol. 2008 Jan; 27(1):42-52.
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Kennedy L, Liu S, Shi-Wen X, Chen Y, Eastwood M, Sabetkar M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res. 2007 Mar 10; 313(5):952-64.