Receptors, Interleukin-12
"Receptors, Interleukin-12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for INTERLEUKIN-12. They exist as dimers of beta 1 and beta 2 subunits. Signaling from interleukin-12 receptors occurs through their interaction with JANUS KINASES.
Descriptor ID |
D053707
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MeSH Number(s) |
D12.776.543.750.705.852.420.580
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Concept/Terms |
Receptors, Interleukin-12- Receptors, Interleukin-12
- Receptors, Interleukin 12
- Interleukin-12 Receptor
- Interleukin 12 Receptor
- IL-12 Receptor
- IL 12 Receptor
- Receptor, IL-12
- Receptor, Interleukin-12
- Receptor, Interleukin 12
- IL-12 Receptors
- IL 12 Receptors
- Receptors, IL-12
- Interleukin-12 Receptors
- Interleukin 12 Receptors
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Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-12".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-12".
This graph shows the total number of publications written about "Receptors, Interleukin-12" by people in this website by year, and whether "Receptors, Interleukin-12" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 2 | 2 |
2003 | 0 | 3 | 3 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Interleukin-12" by people in Profiles.
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Zhao Z, Yu S, Fitzgerald DC, Elbehi M, Ciric B, Rostami AM, Zhang GX. IL-12R beta 2 promotes the development of CD4+CD25+ regulatory T cells. J Immunol. 2008 Sep 15; 181(6):3870-6.
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Parihar R, Trotta R, Roda JM, Ferketich AK, Tridandapani S, Caligiuri MA, Carson WE. Src homology 2-containing inositol 5'-phosphatase 1 negatively regulates IFN-gamma production by natural killer cells stimulated with antibody-coated tumor cells and interleukin-12. Cancer Res. 2005 Oct 01; 65(19):9099-107.
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Gran B, Zhang GX, Rostami A. Role of the IL-12/IL-23 system in the regulation of T-cell responses in central nervous system inflammatory demyelination. Crit Rev Immunol. 2004; 24(2):111-28.
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Li J, Gran B, Zhang GX, Ventura ES, Siglienti I, Rostami A, Kamoun M. Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia. J Neurol Sci. 2003 Nov 15; 215(1-2):95-103.
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Zhang GX, Yu S, Gran B, Li J, Siglienti I, Chen X, Calida D, Ventura E, Kamoun M, Rostami A. Role of IL-12 receptor beta 1 in regulation of T cell response by APC in experimental autoimmune encephalomyelitis. J Immunol. 2003 Nov 1; 171(9):4485-92.
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Zhang GX, Gran B, Yu S, Li J, Siglienti I, Chen X, Kamoun M, Rostami A. Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J Immunol. 2003 Feb 15; 170(4):2153-60.
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Markovic-Plese S, Cortese I, Wandinger KP, McFarland HF, Martin R. CD4+CD28- costimulation-independent T cells in multiple sclerosis. J Clin Invest. 2001 Oct; 108(8):1185-94.
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Kondo T, Cortese I, Markovic-Plese S, Wandinger KP, Carter C, Brown M, Leitman S, Martin R. Dendritic cells signal T cells in the absence of exogenous antigen. Nat Immunol. 2001 Oct; 2(10):932-8.