Brugada Syndrome

"Brugada Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Descriptor ID	D053840
MeSH Number(s)	C14.280.067.322 C14.280.123.250 C16.320.100
Concept/Terms	Brugada Syndrome Brugada Syndrome Sudden Unexplained Death Syndrome Brugada Syndrome 1 Brugada Syndrome 1s Sudden Unexplained Nocturnal Death Syndrome Right Bundle Branch Block, ST Segment Elevation, and Sudden Death Syndrome Sudden Unexplained Nocturnal Death Syndrome (SUNDS) Brugada ECG Pattern Brugada ECG Pattern ECG Pattern, Brugada Brugada Type ECG Pattern

Below are MeSH descriptors whose meaning is more general than "Brugada Syndrome".

Diseases [C]
Cardiovascular Diseases [C14]
Heart Diseases [C14.280]
Arrhythmias, Cardiac [C14.280.067]
Brugada Syndrome [C14.280.067.322]
Cardiac Conduction System Disease [C14.280.123]
Brugada Syndrome [C14.280.123.250]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Brugada Syndrome [C16.320.100]

Below are MeSH descriptors whose meaning is related to "Brugada Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Brugada Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Brugada Syndrome" by people in this website by year, and whether "Brugada Syndrome" was a major or minor topic of these publications.

Bar chart showing 99 publications over 18 distinct years, with a maximum of 10 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	3	0	3
2007	3	1	4
2008	9	1	10
2009	7	2	9
2010	4	1	5
2011	6	1	7
2012	1	0	1
2013	8	1	9
2014	4	0	4
2015	5	3	8
2016	5	2	7
2017	4	0	4
2018	7	2	9
2019	3	0	3
2020	5	0	5
2021	5	0	5
2022	3	0	3
2023	3	0	3

Below are the most recent publications written about "Brugada Syndrome" by people in Profiles.

Zeng B, Zhang X, Schimpf R, Powers A, Glikson M, Antzelevitch C, Hu D, Barajas-Martinez H. Functional identification of hot-spot mutations in cardiac calcium channel genes associated with the J wave syndromes. Philos Trans R Soc Lond B Biol Sci. 2023 06 19; 378(1879):20220286.

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Milman A, Sabbag A, Conte G, Postema PG, Andorin A, Gourraud JB, Sacher F, Mabo P, Kim SH, Maeda S, Takahashi Y, Kamakura T, Aiba T, Juang JJ, Michowitz Y, Leshem E, Mizusawa Y, Arbelo E, Huang Z, Denjoy I, Giustetto C, Wijeyeratne YD, Mazzanti A, Brugada R, Casado-Arroyo R, Champagne J, Calo L, Sarquella-Brugada G, Tfelt-Hansen J, Priori SG, Takagi M, Veltmann C, Delise P, Corrado D, Behr ER, Gaita F, Yan GX, Brugada J, Leenhardt A, Wilde AAM, Brugada P, Kusano KF, Hirao K, Nam GB, Probst V, Belhassen B. Characteristics of Patients with Spontaneous Versus Drug-Induced Brugada Electrocardiogram: Sub-Analysis From the SABRUS. Circ Arrhythm Electrophysiol. 2023 01; 16(1):e011360.

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Babapoor S, Port Z, Wiener PC, Rasekhi RT, Farrokhran AB, Mainigi SK. COVID-19 Can Unveil Brugada: A Rare Case. Acta Medica (Hradec Kralove). 2023; 66(2):68-71.

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Chen GX, Barajas-Mart?nez H, Ciconte G, Wu CI, Monasky MM, Xia H, Li B, Capra JA, Guo K, Zhang ZH, Chen X, Yang B, Jiang H, Tse G, Mak CM, Aizawa Y, Gollob MH, Antzelevitch C, Wilde AAM, Pappone C, Hu D. Clinical characteristics and electrophysiologic properties of SCN5A variants in fever-induced Brugada syndrome. EBioMedicine. 2023 Jan; 87:104388.

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Ye D, Zhou W, Hamrick SK, Tester DJ, Kim CSJ, Barajas-Martinez H, Hu D, Giudicessi JR, Antzelevitch C, Ackerman MJ. Acacetin, a Potent Transient Outward Current Blocker, May Be a Novel Therapeutic for KCND3-Encoded Kv4.3 Gain-of-Function-Associated J-Wave Syndromes. Circ Genom Precis Med. 2022 Oct; 15(5):e003238.

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Barc J, Tadros R, Glinge C, Chiang DY, Jouni M, Simonet F, Jurgens SJ, Baudic M, Nicastro M, Potet F, Offerhaus JA, Walsh R, Choi SH, Verkerk AO, Mizusawa Y, Anys S, Minois D, Arnaud M, Duchateau J, Wijeyeratne YD, Muir A, Papadakis M, Castelletti S, Torchio M, Ortu?o CG, Lacunza J, Giachino DF, Cerrato N, Martins RP, Campuzano O, Van Dooren S, Thollet A, Kyndt F, Mazzanti A, Cl?menty N, Bisson A, Corveleyn A, Stallmeyer B, Dittmann S, Saenen J, No?l A, Honarbakhsh S, Rudic B, Marzak H, Rowe MK, Federspiel C, Le Page S, Placide L, Milhem A, Barajas-Martinez H, Beckmann BM, Krapels IP, Steinfurt J, Winkel BG, Jabbari R, Shoemaker MB, Boukens BJ, ?koric-Milosavljevic D, Bikker H, Manevy F, Lichtner P, Ribas?s M, Meitinger T, M?ller-Nurasyid M, Veldink JH, van den Berg LH, Van Damme P, Cusi D, Lanzani C, Rigade S, Charpentier E, Baron E, Bonnaud S, Lecointe S, Donnart A, Le Marec H, Chatel S, Karakachoff M, B?zieau S, London B, Tfelt-Hansen J, Roden D, Odening KE, Cerrone M, Chinitz LA, Volders PG, van de Berg MP, Laurent G, Faivre L, Antzelevitch C, K??b S, Arnaout AA, Dupuis JM, Pasquie JL, Billon O, Roberts JD, Jesel L, Borggrefe M, Lambiase PD, Mansourati J, Loeys B, Leenhardt A, Guicheney P, Maury P, Schulze-Bahr E, Robyns T, Breckpot J, Babuty D, Priori SG, Napolitano C, de Asmundis C, Brugada P, Brugada R, Arbelo E, Brugada J, Mabo P, Behar N, Giustetto C, Molina MS, Gimeno JR, Hasdemir C, Schwartz PJ, Crotti L, McKeown PP, Sharma S, Behr ER, Haissaguerre M, Sacher F, Rooryck C, Tan HL, Remme CA, Postema PG, Delmar M, Ellinor PT, Lubitz SA, Gourraud JB, Tanck MW, George AL, MacRae CA, Burridge PW, Dina C, Probst V, Wilde AA, Schott JJ, Redon R, Bezzina CR. Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nat Genet. 2022 03; 54(3):232-239.

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Huang Y, Chen XM, Barajas-Martinez H, Jiang H, Antzelevitch C, Hu D. Common variants in SCN10A gene associated with Brugada syndrome. Hum Mol Genet. 2021 12 27; 31(2):157-165.

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Zhang ZH, Barajas-Mart?nez H, Xia H, Li B, Capra JA, Clatot J, Chen GX, Chen X, Yang B, Jiang H, Tse G, Aizawa Y, Gollob MH, Scheinman M, Antzelevitch C, Hu D. Distinct Features of Probands With Early Repolarization and Brugada Syndromes Carrying SCN5A Pathogenic Variants. J Am Coll Cardiol. 2021 10 19; 78(16):1603-1617.

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Antzelevitch C, Di Diego JM. J wave syndromes: What's new? Trends Cardiovasc Med. 2022 08; 32(6):350-363.

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Sarica AS, Bor S, Orman MN, Barajas-Martinez H, Juang JJ, Antzelevitch C, Hasdemir C. Frequency of Irritable Bowel Syndrome in Patients with Brugada Syndrome and Drug-Induced Type 1 Brugada Pattern. Am J Cardiol. 2021 07 15; 151:51-56.

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