Nicotinamide Phosphoribosyltransferase
"Nicotinamide Phosphoribosyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).
| Descriptor ID |
D054409
|
| MeSH Number(s) |
D08.811.913.400.725.575
|
| Concept/Terms |
Nicotinamide Phosphoribosyltransferase- Nicotinamide Phosphoribosyltransferase
- Phosphoribosyltransferase, Nicotinamide
- NAMPT Protein
- Pre-B-Cell Colony-Enhancing Factor
- Colony-Enhancing Factor, Pre-B-Cell
- Pre B Cell Colony Enhancing Factor
- Visfatin
- NAmPRTase
- NMN Pyrophosphorylase
|
Below are MeSH descriptors whose meaning is more general than "Nicotinamide Phosphoribosyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Nicotinamide Phosphoribosyltransferase".
This graph shows the total number of publications written about "Nicotinamide Phosphoribosyltransferase" by people in this website by year, and whether "Nicotinamide Phosphoribosyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Nicotinamide Phosphoribosyltransferase" by people in Profiles.
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Nacarelli T, Fukumoto T, Zundell JA, Fatkhutdinov N, Jean S, Cadungog MG, Borowsky ME, Zhang R. NAMPT Inhibition Suppresses Cancer Stem-like Cells Associated with Therapy-Induced Senescence in Ovarian Cancer. Cancer Res. 2020 02 15; 80(4):890-900.
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Nacarelli T, Lau L, Fukumoto T, Zundell J, Fatkhutdinov N, Wu S, Aird KM, Iwasaki O, Kossenkov AV, Schultz D, Noma KI, Baur JA, Schug Z, Tang HY, Speicher DW, David G, Zhang R. NAD+ metabolism governs the proinflammatory senescence-associated secretome. Nat Cell Biol. 2019 03; 21(3):397-407.
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Reda R, Shehab A, Soliman D, Gabr A, Abbass A. Serum visfatin levels in a group of Egyptian obese individuals. Egypt J Immunol. 2011; 18(1):25-32.