Group X Phospholipases A2
"Group X Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.
| Descriptor ID |
D054509
|
| MeSH Number(s) |
D08.811.277.352.100.680.750.937.750.887
|
| Concept/Terms |
Group X Phospholipases A2- Group X Phospholipases A2
- Group X Secretory Phospholipase A2
- sPLA2-X
- Phospholipase A2, Group X
- Phospholipases A2, Group X
- sPLA(2)-X
- Group X Secretory Phospholipase A(2)
- GX sPLA(2)
|
Below are MeSH descriptors whose meaning is more general than "Group X Phospholipases A2".
Below are MeSH descriptors whose meaning is more specific than "Group X Phospholipases A2".
This graph shows the total number of publications written about "Group X Phospholipases A2" by people in this website by year, and whether "Group X Phospholipases A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Group X Phospholipases A2" by people in Profiles.
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Smart BP, Pan YH, Weeks AK, Bollinger JG, Bahnson BJ, Gelb MH. Inhibition of the complete set of mammalian secreted phospholipases A(2) by indole analogues: a structure-guided study. Bioorg Med Chem. 2004 Apr 1; 12(7):1737-49.
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Pan YH, Yu BZ, Singer AG, Ghomashchi F, Lambeau G, Gelb MH, Jain MK, Bahnson BJ. Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes. J Biol Chem. 2002 Aug 9; 277(32):29086-93.