Calcium-Calmodulin-Dependent Protein Kinase Type 2
"Calcium-Calmodulin-Dependent Protein Kinase Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional calcium-calmodulin-dependent protein kinase subtype that occurs as an oligomeric protein comprised of twelve subunits. It differs from other enzyme subtypes in that it lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE.
| Descriptor ID |
D054732
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| MeSH Number(s) |
D08.811.913.696.620.682.700.125.200 D12.644.360.100.200 D12.776.476.100.200
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| Concept/Terms |
Calcium-Calmodulin-Dependent Protein Kinase Type 2- Calcium-Calmodulin-Dependent Protein Kinase Type 2
- Calcium Calmodulin Dependent Protein Kinase Type 2
- CaM PK II
- CaM Kinase II
- CaM-Kinase II
- Calcium-Dependent CaM Kinase II
- Calcium Dependent CaM Kinase II
- Calcium-Calmodulin-Dependent PK Type II
- Calcium Calmodulin Dependent PK Type II
- CaMKII
- Ca(2+)-Calmodulin Dependent Protein Kinase Type II
- CaCMKII
- Calcium-Calmodulin Protein Kinase II
- Calcium Calmodulin Protein Kinase II
- CaM KII
- Calmodulin-Dependent Protein Kinase II
- Calmodulin Dependent Protein Kinase II
Calcium-Calmodulin-Dependent Protein Kinase Type 2 delta Subunit- Calcium-Calmodulin-Dependent Protein Kinase Type 2 delta Subunit
- Calcium Calmodulin Dependent Protein Kinase Type 2 delta Subunit
- CaM Kinase II delta
- CaM KIIdelta
- Calcium-Calmodulin Dependent Protein Kinase II delta
- Calcium Calmodulin Dependent Protein Kinase II delta
Calcium-Calmodulin-Dependent Protein Kinase Type 2 beta Subunit- Calcium-Calmodulin-Dependent Protein Kinase Type 2 beta Subunit
- Calcium Calmodulin Dependent Protein Kinase Type 2 beta Subunit
- CaM KIIbeta
- Calcium-Calmodulin Dependent Protein Kinase II beta
- Calcium Calmodulin Dependent Protein Kinase II beta
- CaM Kinase II beta
Calcium-Calmodulin-Dependent Protein Kinase Type 2 gamma Subunit- Calcium-Calmodulin-Dependent Protein Kinase Type 2 gamma Subunit
- Calcium Calmodulin Dependent Protein Kinase Type 2 gamma Subunit
- Calcium-Calmodulin Dependent Protein Kinase II gamma
- Calcium Calmodulin Dependent Protein Kinase II gamma
- CaM Kinase II gamma
- CaMKIIgamma
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Below are MeSH descriptors whose meaning is more general than "Calcium-Calmodulin-Dependent Protein Kinase Type 2".
Below are MeSH descriptors whose meaning is more specific than "Calcium-Calmodulin-Dependent Protein Kinase Type 2".
This graph shows the total number of publications written about "Calcium-Calmodulin-Dependent Protein Kinase Type 2" by people in this website by year, and whether "Calcium-Calmodulin-Dependent Protein Kinase Type 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2015 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calcium-Calmodulin-Dependent Protein Kinase Type 2" by people in Profiles.
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Tscheschner H, Meinhardt E, Schlegel P, Jungmann A, Lehmann LH, M?ller OJ, Most P, Katus HA, Raake PW. CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression. PLoS One. 2019; 14(4):e0215992.
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Smeyne M, Sladen P, Jiao Y, Dragatsis I, Smeyne RJ. HIF1a is necessary for exercise-induced neuroprotection while HIF2a is needed for dopaminergic neuron survival in the substantia nigra pars compacta. Neuroscience. 2015 Jun 04; 295:23-38.
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Makadia HK, Anderson WD, Fey D, Sauter T, Schwaber JS, Vadigepalli R. Multiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology. Biophys J. 2015 Jan 06; 108(1):211-23.
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Chen X, Nakayama H, Zhang X, Ai X, Harris DM, Tang M, Zhang H, Szeto C, Stockbower K, Berretta RM, Eckhart AD, Koch WJ, Molkentin JD, Houser SR. Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy. J Mol Cell Cardiol. 2011 Mar; 50(3):460-70.
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Komukai K, O-Uchi J, Morimoto S, Kawai M, Hongo K, Yoshimura M, Kurihara S. Role of Ca(2+)/calmodulin-dependent protein kinase II in the regulation of the cardiac L-type Ca(2+) current during endothelin-1 stimulation. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1902-7.
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Morimoto S, O-Uchi J, Kawai M, Hoshina T, Kusakari Y, Komukai K, Sasaki H, Hongo K, Kurihara S. Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart. Biochem Biophys Res Commun. 2009 Dec 04; 390(1):87-92.
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O-Uchi J, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S. Interaction of alpha1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca2+ channel. Circ Res. 2008 Jun 06; 102(11):1378-88.
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O-Uchi J, Komukai K, Kusakari Y, Obata T, Hongo K, Sasaki H, Kurihara S. alpha1-adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes. Proc Natl Acad Sci U S A. 2005 Jun 28; 102(26):9400-5.
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Choi WS, Chahdi A, Kim YM, Fraundorfer PF, Beaven MA. Regulation of phospholipase D and secretion in mast cells by protein kinase A and other protein kinases. Ann N Y Acad Sci. 2002 Jun; 968:198-212.