Nephrogenic Fibrosing Dermopathy
"Nephrogenic Fibrosing Dermopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic, acquired, idiopathic, progressive eruption of the skin that occurs in the context of RENAL FAILURE. It is sometimes accompanied by systemic fibrosis. The pathogenesis seems to be multifactorial, with postulated involvement of circulating fibrocytes. There is a strong association between this disorder and the use of gadolinium-based contrast agents.
Descriptor ID |
D054989
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MeSH Number(s) |
C17.800.553 C23.550.355.550
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Concept/Terms |
Nephrogenic Fibrosing Dermopathy- Nephrogenic Fibrosing Dermopathy
- Dermopathies, Nephrogenic Fibrosing
- Dermopathy, Nephrogenic Fibrosing
- Fibrosing Dermopathies, Nephrogenic
- Fibrosing Dermopathy, Nephrogenic
- Nephrogenic Fibrosing Dermopathies
- Nephrogenic Systemic Fibrosis
- Fibroses, Nephrogenic Systemic
- Fibrosis, Nephrogenic Systemic
- Nephrogenic Systemic Fibroses
- Systemic Fibroses, Nephrogenic
- Systemic Fibrosis, Nephrogenic
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Below are MeSH descriptors whose meaning is more general than "Nephrogenic Fibrosing Dermopathy".
Below are MeSH descriptors whose meaning is more specific than "Nephrogenic Fibrosing Dermopathy".
This graph shows the total number of publications written about "Nephrogenic Fibrosing Dermopathy" by people in this website by year, and whether "Nephrogenic Fibrosing Dermopathy" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 2 | 0 | 2 |
2010 | 3 | 0 | 3 |
2012 | 1 | 0 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nephrogenic Fibrosing Dermopathy" by people in Profiles.
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Clases D, Fingerhut S, Jeibmann A, Sperling M, Doble P, Karst U. LA-ICP-MS/MS improves limits of detection in elemental bioimaging of gadolinium deposition originating from MRI contrast agents in skin and brain tissues. J Trace Elem Med Biol. 2019 Jan; 51:212-218.
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Wermuth PJ, Jimenez SA. Gadolinium compounds signaling through TLR4 and TLR7 in normal human macrophages: establishment of a proinflammatory phenotype and implications for the pathogenesis of nephrogenic systemic fibrosis. J Immunol. 2012 Jul 1; 189(1):318-27.
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Del Galdo F, Wermuth PJ, Addya S, Fortina P, Jimenez SA. NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis. Ann Rheum Dis. 2010 Nov; 69(11):2024-33.
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Del Galdo F, Shaw MA, Jimenez SA. Proteomic analysis identification of a pattern of shared alterations in the secretome of dermal fibroblasts from systemic sclerosis and nephrogenic systemic fibrosis. Am J Pathol. 2010 Oct; 177(4):1638-46.
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Piera-Velazquez S, Louneva N, Fertala J, Wermuth PJ, Del Galdo F, Jimenez SA. Persistent activation of dermal fibroblasts from patients with gadolinium-associated nephrogenic systemic fibrosis. Ann Rheum Dis. 2010 Nov; 69(11):2017-23.
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Newton BB, Jimenez SA. Mechanism of NSF: New evidence challenging the prevailing theory. J Magn Reson Imaging. 2009 Dec; 30(6):1277-83.
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Wermuth PJ, Del Galdo F, Jiménez SA. Induction of the expression of profibrotic cytokines and growth factors in normal human peripheral blood monocytes by gadolinium contrast agents. Arthritis Rheum. 2009 May; 60(5):1508-18.