Primary Graft Dysfunction
"Primary Graft Dysfunction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
Descriptor ID |
D055031
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MeSH Number(s) |
C14.907.725.675 C23.550.767.877.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Primary Graft Dysfunction".
Below are MeSH descriptors whose meaning is more specific than "Primary Graft Dysfunction".
This graph shows the total number of publications written about "Primary Graft Dysfunction" by people in this website by year, and whether "Primary Graft Dysfunction" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2018 | 2 | 1 | 3 |
2019 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Primary Graft Dysfunction" by people in Profiles.
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Uqdah H, Hankins S, Eisen HJ. Something evil this way comes: Proteomic profiling identifies CLEC4C expression as a novel biomarker of primary graft dysfunction after heart transplantation. J Heart Lung Transplant. 2022 03; 41(3):269-270.
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Anandh U, Gowrishankar S, Sharma A, Salama A, Dasgupta I. Kidney transplant dysfunction in a patient with COVID -?19 infection: role of concurrent Sars-Cov 2 nephropathy, chronic rejection and vitamin C-mediated hyperoxalosis: case report. BMC Nephrol. 2021 03 15; 22(1):91.
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Alam A, Milligan GP, Joseph SM. Reconsidering the Diagnostic Criteria of Right Ventricular Primary Graft Dysfunction. J Card Fail. 2020 Nov; 26(11):985-986.
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Krebs R, Morita Y. Inhaled Pulmonary Vasodilators and Thoracic Organ Transplantation: Does Evidence Support Its Use and Cost Benefit? Semin Cardiothorac Vasc Anesth. 2020 Mar; 24(1):67-73.
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Raza FS, Lee AY, Jamil AK, Qin H, Felius J, Rafael AE, Gonzalez-Stawinski GV, Hall SA, Joseph SM, Lima B, Bindra AS. Relation of Vasoplegia in the Absence of Primary Graft Dysfunction to Mortality Following Cardiac Transplantation. Am J Cardiol. 2018 12 01; 122(11):1902-1908.
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Still S, Shaikh AF, Qin H, Felius J, Jamil AK, Saracino G, Chamogeorgakis T, Rafael AE, MacHannaford JC, Joseph SM, Hall SA, Gonzalez-Stawinski GV, Lima B. Reoperative sternotomy is associated with primary graft dysfunction following heart transplantation. Interact Cardiovasc Thorac Surg. 2018 09 01; 27(3):343-349.
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Gong TA, Joseph SM, Lima B, Gonzalez-Stawinski GV, Jamil AK, Felius J, Qin H, Saracino G, Rafael AE, Kale P, Hall SA. Donor predicted heart mass as predictor of primary graft dysfunction. J Heart Lung Transplant. 2018 07; 37(7):826-835.
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Adler JT, Axelrod DA. Regulations' Impact on Donor and Recipient Selection for Liver Transplantation: How Should Outcomes be Measured and MELD Exception Scores be Considered? AMA J Ethics. 2016 Feb 01; 18(2):133-42.
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Diaz-Guzman E, Davenport DL, Zwischenberger JB, Hoopes CW. Lung function and ECMO after lung transplantation. Ann Thorac Surg. 2012 Aug; 94(2):686-7; author reply 687.
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George TJ, Arnaoutakis GJ, Beaty CA, Shah AS, Conte JV, Halushka MK. A novel method of measuring cardiac preservation injury demonstrates University of Wisconsin solution is associated with less ischemic necrosis than Celsior in early cardiac allograft biopsy specimens. J Heart Lung Transplant. 2012 Apr; 31(4):410-8.