Intervertebral Disc Degeneration

"Intervertebral Disc Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.

Descriptor ID	D055959
MeSH Number(s)	C05.116.900.153
Concept/Terms	Intervertebral Disc Degeneration Intervertebral Disc Degeneration Degeneration, Intervertebral Disc Degenerations, Intervertebral Disc Disc Degeneration, Intervertebral Disc Degenerations, Intervertebral Intervertebral Disc Degenerations Intervertebral Disk Degeneration Degeneration, Intervertebral Disk Degenerations, Intervertebral Disk Disk Degeneration, Intervertebral Disk Degenerations, Intervertebral Intervertebral Disk Degenerations Disk Degeneration Degeneration, Disk Degenerations, Disk Disk Degenerations Disk Degradation Degradation, Disk Degradations, Disk Disk Degradations Disc Degeneration Degeneration, Disc Degenerations, Disc Disc Degenerations Disc Degradation Degradation, Disc Degradations, Disc Disc Degradations Degenerative Intervertebral Discs Degenerative Intervertebral Discs Degenerative Intervertebral Disc Disc, Degenerative Intervertebral Discs, Degenerative Intervertebral Intervertebral Disc, Degenerative Intervertebral Discs, Degenerative Degenerative Intervertebral Disks Degenerative Intervertebral Disk Disk, Degenerative Intervertebral Disks, Degenerative Intervertebral Intervertebral Disk, Degenerative Intervertebral Disks, Degenerative

Below are MeSH descriptors whose meaning is more general than "Intervertebral Disc Degeneration".

Diseases [C]
Musculoskeletal Diseases [C05]
Bone Diseases [C05.116]
Spinal Diseases [C05.116.900]
Intervertebral Disc Degeneration [C05.116.900.153]

Below are MeSH descriptors whose meaning is related to "Intervertebral Disc Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Intervertebral Disc Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Intervertebral Disc Degeneration" by people in this website by year, and whether "Intervertebral Disc Degeneration" was a major or minor topic of these publications.

Bar chart showing 164 publications over 17 distinct years, with a maximum of 19 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	0	1	1
2010	5	0	5
2011	11	1	12
2012	8	2	10
2013	14	5	19
2014	7	1	8
2015	14	4	18
2016	9	3	12
2017	3	3	6
2018	10	1	11
2019	14	4	18
2020	11	0	11
2021	12	0	12
2022	5	0	5
2023	7	0	7
2024	4	2	6
2025	3	0	3

Below are the most recent publications written about "Intervertebral Disc Degeneration" by people in Profiles.

Pennington Z, Hamouda A, Martini M, Kumar R, Mikula AL, Potes MA, Bydon M, Clarke MJ, Krauss WE, Nassr AN, Freedman BA, Sebastian AS, Fogelson JL, Elder BD. Comparison of Sagittal Plane Correction With "Bullet" Versus "Banana" Type Transforaminal Lumbar Interbody Fusion Devices. Oper Neurosurg. 2025 Nov 01; 29(5):624-632.

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Ottone OK, Mundo JJ, Kwakye BN, Slaweski A, Collins JA, Wu Q, Connelly MA, Niaziorimi F, van de Wetering K, Risbud MV. Oral Citrate Supplementation Mitigates Age-Associated Pathologic Intervertebral Disc Calcification in LG/J Mice. Aging Cell. 2025 May; 24(5):e14504.

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Lou J, Ryan R, Wang D. Biologic Therapies for Discogenic Pain. Curr Pain Headache Rep. 2025 Feb 11; 29(1):45.

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Tarawneh OH, Narayanan R, Trenchfield D, Lee Y, Issa TZ, Dulitzki Y, Pashaee B, Maddy K, Bash H, Karthikeyan G, Kaye LD, Mangan JJ, Canseco JA, Hilibrand AS, Vaccaro AR, Kepler CK, Schroeder GD, Lee JK. Impact of Preoperative Intervertebral Disc Degeneration on Patient-Reported Outcome Measures After Lumbar Fusion. World Neurosurg. 2024 09; 189:e787-e793.

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Levy HA, Pinter ZW, Reed R, Harmer JR, Raftery K, Nathani KR, Katsos K, Bydon M, Fogelson JL, Elder BD, Currier BL, Newell N, Nassr AN, Freedman BA, Karamian BA, Sebastian AS. Transforaminal lumbar interbody fusion subsidence: computed tomography analysis of incidence, associated risk factors, and impact on outcomes. J Neurosurg Spine. 2024 Oct 01; 41(4):463-472.

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Khachatryan A, Phillips FM, Lanman TH, Andersson GB, Jacobs JJ, Kurtz SM. Proposal for a classification system of radiographic bone changes after cervical disc replacement. J Orthop Surg Res. 2024 Apr 03; 19(1):218.

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Ruffilli A, Traversari M, Manzetti M, Viroli G, Artioli E, Zielli SO, Mazzotti A, Faldini C. Comparable rates of lumbar disc degeneration at long-term following adolescent idiopathic scoliosis spinal fusion extended to L3 or L4: systematic review and meta-analysis. Spine Deform. 2024 Jul; 12(4):877-901.

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Issa TZ, Haider AA, Lambrechts MJ, Sherman MB, Canseco JA, Vaccaro AR, Schroeder GD, Kepler CK, Hilibrand AS. Preoperative Oswestry Disability Index Should not be Utilized to Determine Surgical Eligibility for Patients Requiring Lumbar Fusion for Degenerative Lumbar Spine Disease. Spine (Phila Pa 1976). 2024 Jul 15; 49(14):965-972.

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Novais EJ, Narayanan R, Canseco JA, van de Wetering K, Kepler CK, Hilibrand AS, Vaccaro AR, Risbud MV. A new perspective on intervertebral disc calcification-from bench to bedside. Bone Res. 2024 01 22; 12(1):3.

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Phillips FM, Coric D, Sasso R, Lanman T, Lavelle W, Lauryssen C, Albert T, Cammisa F, Milam RA. Prospective, multicenter clinical trial comparing the M6-C compressible cervical disc with anterior cervical discectomy and fusion for the treatment of single-level degenerative cervical radiculopathy: 5-year results of an FDA investigational device exemption study. Spine J. 2024 02; 24(2):219-230.

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