Intervertebral Disc Degeneration
"Intervertebral Disc Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.
| Descriptor ID |
D055959
|
| MeSH Number(s) |
C05.116.900.153
|
| Concept/Terms |
Intervertebral Disc Degeneration- Intervertebral Disc Degeneration
- Degeneration, Intervertebral Disc
- Degenerations, Intervertebral Disc
- Disc Degeneration, Intervertebral
- Disc Degenerations, Intervertebral
- Intervertebral Disc Degenerations
- Intervertebral Disk Degeneration
- Degeneration, Intervertebral Disk
- Degenerations, Intervertebral Disk
- Disk Degeneration, Intervertebral
- Disk Degenerations, Intervertebral
- Intervertebral Disk Degenerations
- Disk Degeneration
- Degeneration, Disk
- Degenerations, Disk
- Disk Degenerations
- Disk Degradation
- Degradation, Disk
- Degradations, Disk
- Disk Degradations
- Disc Degeneration
- Degeneration, Disc
- Degenerations, Disc
- Disc Degenerations
- Disc Degradation
- Degradation, Disc
- Degradations, Disc
- Disc Degradations
Degenerative Intervertebral Discs- Degenerative Intervertebral Discs
- Degenerative Intervertebral Disc
- Disc, Degenerative Intervertebral
- Discs, Degenerative Intervertebral
- Intervertebral Disc, Degenerative
- Intervertebral Discs, Degenerative
- Degenerative Intervertebral Disks
- Degenerative Intervertebral Disk
- Disk, Degenerative Intervertebral
- Disks, Degenerative Intervertebral
- Intervertebral Disk, Degenerative
- Intervertebral Disks, Degenerative
|
Below are MeSH descriptors whose meaning is more general than "Intervertebral Disc Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Intervertebral Disc Degeneration".
This graph shows the total number of publications written about "Intervertebral Disc Degeneration" by people in this website by year, and whether "Intervertebral Disc Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 5 | 0 | 5 |
| 2011 | 10 | 1 | 11 |
| 2012 | 6 | 1 | 7 |
| 2013 | 5 | 3 | 8 |
| 2014 | 3 | 0 | 3 |
| 2015 | 9 | 1 | 10 |
| 2016 | 5 | 1 | 6 |
| 2017 | 3 | 1 | 4 |
| 2018 | 6 | 1 | 7 |
| 2019 | 9 | 3 | 12 |
| 2020 | 4 | 0 | 4 |
| 2021 | 7 | 0 | 7 |
| 2022 | 4 | 0 | 4 |
| 2023 | 5 | 0 | 5 |
| 2024 | 2 | 0 | 2 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Intervertebral Disc Degeneration" by people in Profiles.
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Lou J, Ryan R, Wang D. Biologic Therapies for Discogenic Pain. Curr Pain Headache Rep. 2025 Feb 11; 29(1):45.
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Khachatryan A, Phillips FM, Lanman TH, Andersson GB, Jacobs JJ, Kurtz SM. Proposal for a classification system of radiographic bone changes after cervical disc replacement. J Orthop Surg Res. 2024 Apr 03; 19(1):218.
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Novais EJ, Narayanan R, Canseco JA, van de Wetering K, Kepler CK, Hilibrand AS, Vaccaro AR, Risbud MV. A new perspective on intervertebral disc calcification-from bench to bedside. Bone Res. 2024 Jan 22; 12(1):3.
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Phillips FM, Coric D, Sasso R, Lanman T, Lavelle W, Lauryssen C, Albert T, Cammisa F, Milam RA. Prospective, multicenter clinical trial comparing the M6-C compressible cervical disc with anterior cervical discectomy and fusion for the treatment of single-level degenerative cervical radiculopathy: 5-year results of an FDA investigational device exemption study. Spine J. 2024 02; 24(2):219-230.
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Du JY, Gonzalez GA, Albert TJ, Rhee JM, Riew KD, Vaccaro AR, Harrop JS. Past, Present, and Future of Cervical Disc Arthroplasty: Insights From Presidents of the Cervical Spine Research Society. Clin Spine Surg. 2023 11 01; 36(9):331-334.
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Ohnishi T, Tran V, Sao K, Ramteke P, Querido W, Barve RA, van de Wetering K, Risbud MV. Loss of function mutation in Ank causes aberrant mineralization and acquisition of osteoblast-like-phenotype by the cells of the intervertebral disc. Cell Death Dis. 2023 07 19; 14(7):447.
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Ruffilli A, Viroli G, Neri S, Traversari M, Barile F, Manzetti M, Assirelli E, Ialuna M, Vita F, Faldini C. Mechanobiology of the Human Intervertebral Disc: Systematic Review of the Literature and Future Perspectives. Int J Mol Sci. 2023 Feb 01; 24(3).
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Vincent KF, Bundock J, Dona CPG, Chenna SS, Mohanty S, Saini C, Hong J, Albert TJ, Dahia CL. Loss of lumbar disc height with age and its impact on pain and sensitivity associated behaviors in mice. Eur Spine J. 2023 03; 32(3):848-858.
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Johnston SN, Madhu V, Shapiro IM, Risbud MV. Conditional Deletion of HIF-2a in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age-Dependent Structural Changes in Intervertebral Disc. J Bone Miner Res. 2022 12; 37(12):2512-2530.
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Ottone OK, Kim C, Collins JA, Risbud MV. The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration. Front Immunol. 2022; 13:882407.