Drug Substitution

"Drug Substitution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The practice of replacing one prescribed drug with another that is expected to have the same clinical or psychological effect.

Descriptor ID	D057915
MeSH Number(s)	E02.319.307.312 N02.421.668.778.500.312
Concept/Terms	Drug Substitution Drug Substitution Drug Substitutions Substitution, Drug Substitutions, Drug Therapeutic Substitution Substitution, Therapeutic Substitutions, Therapeutic Therapeutic Substitutions Drug Switching Drug Switchings Switching, Drug Switchings, Drug Generic Substitution Generic Substitution Generic Substitutions Substitution, Generic Substitutions, Generic

Below are MeSH descriptors whose meaning is more general than "Drug Substitution".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Drug Therapy [E02.319]
Drug Prescriptions [E02.319.307]
Drug Substitution [E02.319.307.312]
Health Care [N]
Health Care Facilities, Manpower, and Services [N02]
Health Services [N02.421]
Pharmaceutical Services [N02.421.668]
Prescriptions [N02.421.668.778]
Drug Prescriptions [N02.421.668.778.500]
Drug Substitution [N02.421.668.778.500.312]

Below are MeSH descriptors whose meaning is related to "Drug Substitution".

Below are MeSH descriptors whose meaning is more specific than "Drug Substitution".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Substitution" by people in this website by year, and whether "Drug Substitution" was a major or minor topic of these publications.

Bar chart showing 28 publications over 11 distinct years, with a maximum of 4 publications in 2016 and 2018 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	0	2	2
2012	0	1	1
2013	2	1	3
2014	0	1	1
2015	2	1	3
2016	3	1	4
2017	0	3	3
2018	3	1	4
2019	1	3	4
2020	0	1	1
2024	0	2	2

Below are the most recent publications written about "Drug Substitution" by people in Profiles.

Durrani AF, Momenaei B, Wakabayashi T, Vemula S, Pandit SA, Hsu J, Ho AC, Spirn MJ, Klufas MA, Garg SJ, Vander JF, Regillo CD, Chiang A, Kuriyan AE, Yonekawa Y. Conversion to faricimab after prior anti-vascular endothelial growth factor therapy for persistent diabetic macular oedema. Br J Ophthalmol. 2024 08 22; 108(9):1257-1262.

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Jabbour S, Paik JS, Aleppo G, Sharma P, Gomez Valderas E, Benneyworth BD. Switching to Tirzepatide 5?mg From Glucagon-Like Peptide-1 Receptor Agonists: Clinical Expectations in the First 12 Weeks of Treatment. Endocr Pract. 2024 Aug; 30(8):701-709.

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Deaner JD, Srivastava SK, Hajj-Ali RA, Lowder CY, Venkat AG, Baynes K, Sharma S. Recurrence Rates of Inflammation after Switching from the Originator Infliximab to Biosimilar Infliximab-abda for Noninfectious Uveitis. Am J Ophthalmol. 2021 05; 225:172-177.

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Lo KBU, Azmaiparashvili Z. Desquamating pustular rash. Cleve Clin J Med. 2019 12; 86(12):780-781.

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Siddiq N, Bergstrom C, Anderson LD, Nagalla S. Bleeding due to acquired dysfibrinogenemia as the initial presentation of multiple myeloma. BMJ Case Rep. 2019 Jul 17; 12(7).

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Crawford ED, Tombal B, Keane T, Boccardo F, Miller K, Shore N, Moul JW, Damber JE, Collette L, Persson BE. FSH suppression and tumour control in patients with prostate cancer during androgen deprivation with a GnRH agonist or antagonist. Scand J Urol. 2018 Oct - Dec; 52(5-6):349-357.

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Vishnevsky A, Savage MP, Fischman DL. Treatment of Clopidogrel Hypersensitivity: The Jefferson Approach. Curr Vasc Pharmacol. 2019; 17(2):123-126.

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Black KJ, Nasrallah H, Isaacson S, Stacy M, Pahwa R, Adler CH, Alva G, Cooney JW, Kremens D, Menza MA, Meyer JM, Patkar AA, Simuni T, Morrissette DA, Stahl SM. Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus. CNS Spectr. 2018 12; 23(6):402-413.

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Gajanana D, Weintraub WS, Kolm P, Rogers T, Iantorno M, Buchanan KD, Ben-Dor I, Pichard AD, Satler LF, Thourani VH, Torguson R, Okubagzi PG, Waksman R. The impact of in-hospital P2Y12 inhibitor switch in patients with acute coronary syndrome. Cardiovasc Revasc Med. 2018 12; 19(8):912-916.

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O'Brien EC, Holmes DN, Thomas L, Fonarow GC, Kowey PR, Ansell JE, Mahaffey KW, Gersh BJ, Peterson ED, Piccini JP, Hylek EM. Therapeutic Strategies Following Major, Clinically Relevant Nonmajor,?and Nuisance Bleeding in Atrial Fibrillation: Findings From?ORBIT-AF. J Am Heart Assoc. 2018 06 09; 7(12).

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