Drug Substitution

"Drug Substitution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The practice of replacing one prescribed drug with another that is expected to have the same clinical or psychological effect.

Descriptor ID	D057915
MeSH Number(s)	E02.319.307.312 N02.421.668.778.500.312
Concept/Terms	Drug Substitution Drug Substitution Drug Substitutions Substitution, Drug Substitutions, Drug Therapeutic Substitution Substitution, Therapeutic Substitutions, Therapeutic Therapeutic Substitutions Drug Switching Drug Switchings Switching, Drug Switchings, Drug Generic Substitution Generic Substitution Generic Substitutions Substitution, Generic Substitutions, Generic

Below are MeSH descriptors whose meaning is more general than "Drug Substitution".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Drug Therapy [E02.319]
Drug Prescriptions [E02.319.307]
Drug Substitution [E02.319.307.312]
Health Care [N]
Health Care Facilities, Manpower, and Services [N02]
Health Services [N02.421]
Pharmaceutical Services [N02.421.668]
Prescriptions [N02.421.668.778]
Drug Prescriptions [N02.421.668.778.500]
Drug Substitution [N02.421.668.778.500.312]

Below are MeSH descriptors whose meaning is related to "Drug Substitution".

Below are MeSH descriptors whose meaning is more specific than "Drug Substitution".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Substitution" by people in this website by year, and whether "Drug Substitution" was a major or minor topic of these publications.

Bar chart showing 23 publications over 10 distinct years, with a maximum of 4 publications in 2015 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	1	0	1
2011	0	2	2
2013	2	1	3
2014	1	0	1
2015	2	2	4
2016	1	2	3
2017	0	4	4
2018	1	0	1
2019	0	2	2
2020	1	1	2

Below are the most recent publications written about "Drug Substitution" by people in Profiles.

Deaner JD, Srivastava SK, Hajj-Ali RA, Lowder CY, Venkat AG, Baynes K, Sharma S. Recurrence Rates of Inflammation after Switching from the Originator Infliximab to Biosimilar Infliximab-abda for Noninfectious Uveitis. Am J Ophthalmol. 2021 05; 225:172-177.

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Dal?n J, Luttropp K, Svedbom A, Black CM, Kachroo S. Healthcare-Related Costs Associated with Switching Subcutaneous Tumor Necrosis Factor-a Inhibitor in the Treatment of Inflammatory Arthritis: a Retrospective Study. Adv Ther. 2020 09; 37(9):3746-3760.

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Sharma A, Hafeez Faridi M, Kumar N, Parachuri N, Sharma R, Kuppermann BD, Bandello F, Loewenstein A, Regillo CD. Immunogenicity and efficacy after switching from original Ranibizumab to a Ranibizumab biosimilar: real-world data. Eye (Lond). 2020 06; 34(6):1008-1009.

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Lo KBU, Azmaiparashvili Z. Desquamating pustular rash. Cleve Clin J Med. 2019 12; 86(12):780-781.

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O'Brien EC, Holmes DN, Thomas L, Fonarow GC, Kowey PR, Ansell JE, Mahaffey KW, Gersh BJ, Peterson ED, Piccini JP, Hylek EM. Therapeutic Strategies Following Major, Clinically Relevant Nonmajor,?and Nuisance Bleeding in Atrial Fibrillation: Findings From?ORBIT-AF. J Am Heart Assoc. 2018 06 09; 7(12).

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Dal?n J, Svedbom A, Black CM, Kachroo S. Second-line treatment persistence and costs among patients with immune-mediated rheumatic diseases treated with subcutaneous TNF-alpha inhibitors. Rheumatol Int. 2017 Dec; 37(12):2049-2058.

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Essebag V, Proietti R, Birnie DH, Wang J, Douketis J, Coutu B, Parkash R, Lip GYH, Hohnloser SH, Moriarty A, Oldgren J, Connolly SJ, Ezekowitz M, Healey JS. Short-term dabigatran interruption before cardiac rhythm device implantation: multi-centre experience from the RE-LY trial. Europace. 2017 Oct 01; 19(10):1630-1636.

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Teo KC, Lau GKK, Mak RHY, Leung HY, Chang RSK, Tse MY, Lee R, Leung GKK, Ho SL, Cheung RTF, Siu DCW, Chan KH. Antiplatelet Resumption after Antiplatelet-Related Intracerebral Hemorrhage: A?Retrospective Hospital-Based Study. World Neurosurg. 2017 Oct; 106:85-91.

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Black-Maier E, Kim S, Steinberg BA, Fonarow GC, Freeman JV, Kowey PR, Ansell J, Gersh BJ, Mahaffey KW, Naccarelli G, Hylek EM, Go AS, Peterson ED, Piccini JP. Oral anticoagulation management in patients with atrial fibrillation undergoing cardiac implantable electronic device implantation. Clin Cardiol. 2017 Sep; 40(9):746-751.

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Hepp Z, Dodick DW, Varon SF, Chia J, Matthew N, Gillard P, Hansen RN, Devine EB. Persistence and switching patterns of oral migraine prophylactic medications among patients with chronic migraine: A retrospective claims analysis. Cephalalgia. 2017 Apr; 37(5):470-485.

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