Sunday Shoyele

TitleAssoc Prof CHP
InstitutionThomas Jefferson University
DepartmentJSP - Pharmaceutical Science
Address901 Walnut Street
Philadelphia PA 19107
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    Application of nanotechnology in the targeted delivery of RNAi, small organic molecules and protein therapeutics to tumors and other diseases. Analysis of biomolecules using circular dichroism, Fluorescence spectroscopy, Gel electrophoresis, Size exclusion chromatography, Thermal analysis and Raman spectroscopy.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sacko K, Thangavel K, Shoyele SA. Codelivery of Genistein and miRNA-29b to A549 Cells Using Aptamer-Hybrid Nanoparticle Bioconjugates. Nanomaterials (Basel). 2019 Jul 23; 9(7). PMID: 31340494.
      Citations:    
    2. Kundur S, Prayag A, Selvakumar P, Nguyen H, McKee L, Cruz C, Srinivasan A, Shoyele S, Lakshmikuttyamma A. Synergistic anticancer action of quercetin and curcumin against triple-negative breast cancer cell lines. J Cell Physiol. 2018 Nov 27. PMID: 30478904.
      Citations:    
    3. Agrawal M, Saraf S, Saraf S, Antimisiaris SG, Chougule MB, Shoyele SA, Alexander A. Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs. J Control Release. 2018 Jul 10; 281:139-177. PMID: 29772289.
      Citations:    
    4. Agrawal M, Saraf S, Saraf S, Antimisiaris SG, Hamano N, Li SD, Chougule M, Shoyele SA, Gupta U, Alexander A. Recent advancements in the field of nanotechnology for the delivery of anti-Alzheimer drug in the brain region. Expert Opin Drug Deliv. 2018 Jun; 15(6):589-617. PMID: 29733231.
      Citations:    
    5. Thangavel C, Perepelyuk M, Boopathi E, Liu Y, Polischak S, Deshpande DA, Rafiq K, Dicker AP, Knudsen KE, Shoyele SA, Den RB. Improvement in Therapeutic Efficacy and Reduction in Cellular Toxicity: Introduction of a Novel Anti-PSMA-Conjugated Hybrid Antiandrogen Nanoparticle. Mol Pharm. 2018 Apr 04. PMID: 29616555.
      Citations:    
    6. Perepelyuk M, Sacko K, Thangavel K, Shoyele SA. Evaluation of MUC1-Aptamer Functionalized Hybrid Nanoparticles for Targeted Delivery of miRNA-29b to Nonsmall Cell Lung Cancer. Mol Pharm. 2018 Mar 05; 15(3):985-993. PMID: 29432024.
      Citations:    
    7. Thangavel C, Boopathi E, Liu Y, McNair C, Haber A, Perepelyuk M, Bhardwaj A, Addya S, Ertel A, Shoyele S, Birbe R, Salvino JM, Dicker AP, Knudsen KE, Den RB. Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer. Clin Cancer Res. 2018 Mar 15; 24(6):1402-1414. PMID: 29311118.
      Citations:    
    8. Perepelyuk M, Shoyele O, Birbe R, Thangavel C, Liu Y, Den RB, Snook AE, Lu B, Shoyele SA. siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K-ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer. Mol Ther Nucleic Acids. 2017 Mar 17; 6:259-268. PMID: 28325292.
      Citations:    
    9. Perepelyuk M, Maher C, Lakshmikuttyamma A, Shoyele SA. Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins. Int J Nanomedicine. 2016; 11:3533-44. PMID: 27555773.
      Citations:    
    10. Perepelyuk M, Thangavel C, Liu Y, Den RB, Lu B, Snook AE, Shoyele SA. Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model. Mol Ther Nucleic Acids. 2016; 5:e282. PMID: 26812654.
      Citations:    
    11. Dim N, Perepelyuk M, Gomes O, Thangavel C, Liu Y, Den R, Lakshmikuttyamma A, Shoyele SA. Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation. J Nanobiotechnology. 2015; 13(1):61. PMID: 26410728.
      Citations:    
    12. Srinivasan A, Thangavel C, Liu Y, Shoyele S, Den RB, Selvakumar P, Lakshmikuttyamma A. Quercetin regulates ß-catenin signaling and reduces the migration of triple negative breast cancer. Mol Carcinog. 2015 May 12. PMID: 25968914.
      Citations:    
    13. Asha R. Srinivasan and Sunday A. Shoyele. Influence of Surface Modification and the pH on the Release Mechanisms and Kinetics of Erlotinib from Antibody-Functionalized Chitosan Nanoparticles. Industrial and Engineering Chemistry Research. 2014; 53(8):2987-2993.
    14. Srinivasan AR, Lakshmikuttyamma A, Shoyele SA. Investigation of the Stability and Cellular Uptake of Self-Associated Monoclonal Antibody (MAb) Nanoparticles by Non-Small Lung Cancer Cells. Mol Pharm. 2013 Sep 3; 10(9):3275-84. PMID: 23915336.
      Citations:    
    15. Srinivasan AR, Shoyele SA. Self-Associated Submicron IgG1 Particles for Pulmonary Delivery: Effects of Non-ionic Surfactants on Size, Shape, Stability, and Aerosol Performance. AAPS PharmSciTech. 2013 Mar; 14(1):200-10. PMID: 23255200.
      Citations:    
    16. Shoyele SA, Sivadas N, Cryan SA. The effects of excipients and particle engineering on the biophysical stability and aerosol performance of parathyroid hormone (1-34) prepared as a dry powder for inhalation. AAPS PharmSciTech. 2011 Mar; 12(1):304-11. PMID: 21271316.
      Citations:    
    17. Shoyele SA. Controlling the release of proteins/peptides via the pulmonary route. Methods Mol Biol. 2008; 437:141-8. PMID: 18369966.
      Citations:    
    18. Shoyele SA. Engineering protein particles for pulmonary drug delivery. Methods Mol Biol. 2008; 437:149-60. PMID: 18369967.
      Citations:    
    19. Shoyele SA, Cawthorne S. Particle engineering techniques for inhaled biopharmaceuticals. Adv Drug Deliv Rev. 2006 Oct 31; 58(9-10):1009-29. PMID: 17005293.
      Citations:    
    20. Shoyele SA, Slowey A. Prospects of formulating proteins/peptides as aerosols for pulmonary drug delivery. Int J Pharm. 2006 May 11; 314(1):1-8. PMID: 16563674.
      Citations:    
    Shoyele's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (27)
    Explore
    _
    Co-Authors (11)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _