Thomas Jefferson University

Scott Waldman

TitlePhysician
InstitutionThomas Jefferson University
DepartmentChairman - JMC - Thomas Jefferson University
Address1020 Locust Street
Philadelphia PA 19107
Phone2159556086
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    R55DK043805     (WALDMAN, SCOTT A.)Sep 30, 1992 - Sep 29, 1994
    NIH
    MOLECULAR CHARACTERIZATION OF E COLI TOXIN RECEPTORS
    Role: Principal Investigator
    T32GM008562     (KRAFT, WALTER K)Jul 1, 1995 - Jun 30, 2030
    NIH
    Clinical Pharmacology Training Program
    Role: Principal Investigator
    R01GM050290     (WALDMAN, SCOTT A.)Jul 1, 1996 - Jun 30, 2001
    NIH
    VITAMIN D3 25-HYDROXYLASE CHARACTERIZATION ®ULATION
    Role: Principal Investigator
    R25CA069277     (WALDMAN, SCOTT A.)Aug 1, 1997 - Mar 31, 2009
    NIH
    Short-term Training Program in Translational Cancer Rese
    Role: Principal Investigator
    R01CA075123     (WALDMAN, SCOTT A.)Jun 5, 1998 - Jan 31, 2009
    NIH
    GUANYLYL CYCLASE C AS A BI0MARKER FOR COLORECTAL CANCER
    Role: Principal Investigator
    R01HL059214     (WALDMAN, SCOTT A.)Jul 1, 1998 - Jun 30, 2002
    NIH
    ALLOSTERIC INHIBITION OF GUANYLYL CYCLASE BY NUCLEOTIDES
    Role: Principal Investigator
    R21CA079663     (WALDMAN, SCOTT A.)Jan 1, 1999 - Dec 31, 2002
    NIH
    GUANYLYL CYCLASE C IN BLOOD AND COLORECTAL CANCER
    Role: Principal Investigator
    K30HL004522     (WALDMAN, SCOTT A.)Sep 30, 2000 - Aug 31, 2005
    NIH
    TRAINING PROGRAM IN HUMAN INVESTIGATION
    Role: Principal Investigator
    K30RR022299     (WALDMAN, SCOTT A.)Sep 30, 2000 - Jun 30, 2011
    NIH
    Training Program in Human Investigation
    Role: Principal Investigator
    R01CA095026     (WALDMAN, SCOTT A.)Aug 1, 2003 - May 31, 2010
    NIH
    Guanylyl Cyclase C in Blood and Colorectal Cancer
    Role: Principal Investigator
    RC1CA146033     (WALDMAN, SCOTT A.)Sep 30, 2009 - Aug 31, 2011
    NIH
    Occult lymph node metastases and racial disparities in colon cancer outcomes
    Role: Principal Investigator
    R01CA170533     (WALDMAN, SCOTT A)Aug 1, 2012 - Nov 30, 2016
    NIH
    GUCY2C hormone signaling at the intersection of obesity and colorectal cancer(PQ1
    Role: Principal Investigator
    R01CA206026     (WALDMAN, SCOTT A)May 9, 2016 - Apr 30, 2021
    NIH
    (PQ1) GUCY2C hormone loss translates APC-Beta-catenin mutations into epithelial transformation
    Role: Principal Investigator
    R01CA204481     (WALDMAN, SCOTT A)Jan 1, 2017 - Dec 31, 2021
    NIH
    Guanylin GUCY2C axis in Colorectal Cancer Initiation
    Role: Principal Investigator
    R21NS130388     (WALDMAN, SCOTT A)Sep 1, 2023 - Aug 31, 2025
    NIH
    Neuroprotection by the GUCY2C gut-brain axis in Parkinson's disease
    Role: Principal Investigator
    R01DK138834     (WALDMAN, SCOTT A)Sep 19, 2023 - Jul 31, 2028
    NIH
    Targeting visceral pain through intestinal neuropod cell GUCY2C signaling
    Role: Principal Investigator
    T32HD117733     (KRAFT, WALTER K)May 21, 2025 - Apr 30, 2030
    NIH
    Clinical Pharmacology Training Program
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Baybutt TR, Entezari AA, Caspi A, Staudt RE, Carlson RD, Waldman SA, Snook AE. CD8a Structural Domains Enhance GUCY2C CAR-T Cell Efficacy. Cancer Biol Ther. 2024 Dec 31; 25(1):2398801. PMID: 39315411.
      Citations:    
    2. Cheslow L, Byrne M, Kopenhaver JS, Iacovitti L, Smeyne RJ, Snook AE, Waldman SA. GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults. NPJ Parkinsons Dis. 2024 Apr 13; 10(1):83. PMID: 38615030.
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    3. Cheslow L, Snook AE, Waldman SA. Biomarkers for Managing Neurodegenerative Diseases. Biomolecules. 2024 03 26; 14(4). PMID: 38672416.
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    4. Londregan A, Alexander TD, Covarrubias M, Waldman SA. Fundamental Neurochemistry Review: The role of enteroendocrine cells in visceral pain. J Neurochem. 2023 12; 167(6):719-732. PMID: 38037432.
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    5. Barton JR, Londregan AK, Alexander TD, Entezari AA, Covarrubias M, Waldman SA. Enteroendocrine cell regulation of the gut-brain axis. Front Neurosci. 2023; 17:1272955. PMID: 38027512.
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    6. Cheslow L, Byrne M, Kopenhaver JS, Iacovitti L, Smeyne RJ, Snook AE, Waldman SA. GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults. Res Sq. 2023 Oct 13. PMID: 37886524.
      Citations:    
    7. Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Koesling D, Kuhn M, MacEwan D, Monie TP, Potter LR, Russwurm M, Schmidt HHHW, Stasch JP, Waldman SA. The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 2023 10; 180 Suppl 2:S241-S288. PMID: 38123155.
      Citations:    
    8. Barton JR, Londregan AK, Alexander TD, Entezari AA, Bar-Ad S, Cheng L, Lepore AC, Snook AE, Covarrubias M, Waldman SA. Intestinal neuropod cell GUCY2C regulates visceral pain. J Clin Invest. 2023 02 15; 133(4). PMID: 36548082.
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    9. Crutcher M, Waldman S. Biomarkers in the development of individualized treatment regimens for colorectal cancer. Front Med (Lausanne). 2022; 9:1062423. PMID: 36530921.
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    10. Crutcher MM, Snook AE, Waldman SA. Overview of predictive and prognostic biomarkers and their importance in developing a clinical pharmacology treatment plan in colorectal cancer patients. Expert Rev Clin Pharmacol. 2022 Nov; 15(11):1317-1326. PMID: 36259230.
      Citations:    
    11. Caspi A, Entezari AA, Crutcher M, Snook AE, Waldman SA. Guanylyl cyclase C as a diagnostic and therapeutic target in colorectal cancer. Per Med. 2022 09; 19(5):457-472. PMID: 35920071.
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    12. Flickinger JC, Staudt RE, Singh J, Carlson RD, Barton JR, Baybutt TR, Rappaport JA, Zalewski A, Pattison A, Waldman SA, Snook AE. Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapy. NPJ Vaccines. 2022 Jun 23; 7(1):61. PMID: 35739202.
      Citations:    
    13. Sayuk GS, Waldman SA, Brenner DM. Mechanisms of Action of Current Pharmacologic Options for the Treatment of Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation. Am J Gastroenterol. 2022 04 01; 117(4S):S6-S13. PMID: 35354770.
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    14. Brenner DM, Harris LA, Chang CH, Waldman SA, Poppers DM, Kassebaum-Ladewski A, Sayuk GS. Real-World Treatment Strategies to Improve Outcomes in Patients With Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation. Am J Gastroenterol. 2022 04 01; 117(4S):S21-S26. PMID: 35354772.
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    15. Flickinger JC, Singh J, Yarman Y, Carlson RD, Barton JR, Waldman SA, Snook AE. T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C. Front Immunol. 2022; 13:855759. PMID: 35355987.
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    16. Crutcher MM, Baybutt TR, Kopenhaver JS, Snook AE, Waldman SA. Emerging drug targets for colon cancer: A preclinical assessment. Expert Opin Ther Targets. 2022 03; 26(3):207-216. PMID: 35129035.
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    17. Rappaport JA, Entezari AA, Caspi A, Caksa S, Jhaveri AV, Stanek TJ, Ertel A, Kupper J, Fortina PM, McMahon SB, Jaynes JB, Snook AE, Waldman SA. A ?-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2022; 13(4):1276-1296. PMID: 34954189.
      Citations:    
    18. Weinberg DS, Foster NR, Della'Zanna G, McMurray RP, Kraft WK, Pallotto A, Kastenberg DM, Katz LC, Henry CH, Moleski SM, Limburg PJ, Waldman SA. Phase I double-blind, placebo-controlled trial of dolcanatide (SP-333) 27 mg to explore colorectal bioactivity in healthy volunteers. Cancer Biol Ther. 2021 12 02; 22(10-12):544-553. PMID: 34632925.
      Citations:    
    19. Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Kuhn M, MacEwan D, Monie TP, Papapetropoulos A, Potter LR, Schmidt HHHW, Szabo C, Waldman SA. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors. Br J Pharmacol. 2021 Oct; 178 Suppl 1:S264-S312. PMID: 34529829.
      Citations:    
    20. Entezari AA, Snook AE, Waldman SA. Guanylyl cyclase 2C (GUCY2C) in gastrointestinal cancers: recent innovations and therapeutic potential. Expert Opin Ther Targets. 2021 05; 25(5):335-346. PMID: 34056991.
      Citations:    
    21. Kopenhaver J, Crutcher M, Waldman SA, Snook AE. The shifting paradigm of colorectal cancer treatment: a look into emerging cancer stem cell-directed therapeutics to lead the charge toward complete remission. Expert Opin Biol Ther. 2021 10; 21(10):1335-1345. PMID: 33977849.
      Citations:    
    22. Cheslow L, Snook AE, Waldman SA. Emerging targets for the diagnosis of Parkinson's disease: examination of systemic biomarkers. Biomark Med. 2021 06; 15(8):597-608. PMID: 33988462.
      Citations:    
    23. Sharma A, Rao SSC, Kearns K, Orleck KD, Waldman SA. Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders. Aliment Pharmacol Ther. 2021 06; 53(12):1250-1267. PMID: 33909919.
      Citations:    
    24. Zalewski A, Snook AE, Waldman SA. Stem cells as therapeutic targets in colorectal cancer. Per Med. 2021 03; 18(2):171-183. PMID: 33565332.
      Citations:    
    25. Lisby AN, Flickinger JC, Bashir B, Weindorfer M, Shelukar S, Crutcher M, Snook AE, Waldman SA. GUCY2C as a biomarker to target precision therapies for patients with colorectal cancer. Expert Rev Precis Med Drug Dev. 2021; 6(2):117-129. PMID: 34027103.
      Citations:    
    26. Barton JR, Snook AE, Waldman SA. From leptin to lasers: the past and present of mouse models of obesity. Expert Opin Drug Discov. 2021 07; 16(7):777-790. PMID: 33472452.
      Citations:    
    27. Flickinger JC, Rappaport JA, Barton JR, Baybutt TR, Pattison AM, Snook AE, Waldman SA. Guanylyl cyclase C as a biomarker for immunotherapies for the treatment of gastrointestinal malignancies. Biomark Med. 2021 Feb; 15(3):201-217. PMID: 33470843.
      Citations:    
    28. Bartunek J, Terzic A, Davison BA, Behfar A, Sanz-Ruiz R, Wojakowski W, Sherman W, Heyndrickx GR, Metra M, Filippatos GS, Waldman SA, Teerlink JR, Henry TD, Gersh BJ, Hajjar R, Tendera M, Senger S, Cotter G, Povsic TJ, Wijns W. Cardiopoietic stem cell therapy in ischaemic heart failure: long-term clinical outcomes. ESC Heart Fail. 2020 Dec; 7(6):3345-3354. PMID: 33094909.
      Citations:    
    29. Rappaport JA, Waldman SA. An update on guanylyl cyclase C in the diagnosis, chemoprevention, and treatment of colorectal cancer. Expert Rev Clin Pharmacol. 2020 Oct; 13(10):1125-1137. PMID: 32945718.
      Citations:    
    30. Flickinger JC, Singh J, Carlson R, Leong E, Baybutt TR, Barton J, Caparosa E, Pattison A, Rappaport JA, Roh J, Zhan T, Bashir B, Waldman SA, Snook AE. Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity. J Immunother Cancer. 2020 08; 8(2). PMID: 32819976.
      Citations:    
    31. Pattison AM, Barton JR, Entezari AA, Zalewski A, Rappaport JA, Snook AE, Waldman SA. Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity. Cancer Biol Ther. 2020 09 01; 21(9):799-805. PMID: 32594830.
      Citations:    
    32. Blomain ES, Rappaport JA, Pattison AM, Bashir B, Caparosa E, Stem J, Snook AE, Waldman SA. APC-?-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis. Cancer Biol Ther. 2020 05 03; 21(5):441-451. PMID: 32037952.
      Citations:    
    33. Merlino DJ, Barton JR, Charsar BA, Byrne MD, Rappaport JA, Smeyne RJ, Lepore AC, Snook AE, Waldman SA. Two distinct GUCY2C circuits with PMV (hypothalamic) and SN/VTA (midbrain) origin. Brain Struct Funct. 2019 Nov; 224(8):2983-2999. PMID: 31485718.
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    34. Caparosa EM, Stem J, Snook AE, Waldman SA. Biomarker targeting of colorectal cancer stem cells. Biomark Med. 2019 08; 13(11):891-894. PMID: 31385523.
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    35. Chen T, Lin R, Avula L, Sarker R, Yang J, Cha B, Tse CM, McNamara G, Seidler U, Waldman S, Snook A, Bijvelds MJC, de Jonge HR, Li X, Donowitz M. NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells. Am J Physiol Cell Physiol. 2019 10 01; 317(4):C737-C748. PMID: 31365292.
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    36. Waldman SA, Tenenbaum R, Foehl HC, Winkle P, Griffin P. Blunted Evoked Prouroguanylin Endocrine Secretion in Chronic Constipation. Clin Transl Gastroenterol. 2019 07; 10(7):e00016. PMID: 31318728.
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    37. Stem J, Flickinger JC, Merlino D, Caparosa EM, Snook AE, Waldman SA. Therapeutic targeting of gastrointestinal cancer stem cells. Regen Med. 2019 05; 14(4):331-343. PMID: 31025613.
      Citations:    
    38. Snook AE, Baybutt TR, Xiang B, Abraham TS, Flickinger JC, Hyslop T, Zhan T, Kraft WK, Sato T, Waldman SA. Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients. J Immunother Cancer. 2019 04 23; 7(1):104. PMID: 31010434.
      Citations:    
    39. Bashir B, Merlino DJ, Rappaport JA, Gnass E, Palazzo JP, Feng Y, Fearon ER, Snook AE, Waldman SA. Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia. Hum Pathol. 2019 05; 87:103-114. PMID: 30716341.
      Citations:    
    40. Abraham TS, Flickinger JC, Waldman SA, Snook AE. TCR Retrogenic Mice as a Model To Map Self-Tolerance Mechanisms to the Cancer Mucosa Antigen GUCY2C. J Immunol. 2019 02 15; 202(4):1301-1310. PMID: 30642983.
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    41. Waldman SA, Terzic A. Health Care Evolves From Reactive to Proactive. Clin Pharmacol Ther. 2019 01; 105(1):10-13. PMID: 30597564.
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    42. Rappaport JA, Waldman SA. The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. Front Oncol. 2018; 8:299. PMID: 30131940.
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    43. Waldman SA. Prenatal Regeneration in Clinical Practice. Mayo Clin Proc. 2018 06; 93(6):673-675. PMID: 29803314.
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    44. Magee MS, Abraham TS, Baybutt TR, Flickinger JC, Ridge NA, Marszalowicz GP, Prajapati P, Hersperger AR, Waldman SA, Snook AE. Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases. Cancer Immunol Res. 2018 05; 6(5):509-516. PMID: 29615399.
      Citations:    
    45. Waldman SA, Camilleri M. Guanylate cyclase-C as a therapeutic target in gastrointestinal disorders. Gut. 2018 08; 67(8):1543-1552. PMID: 29563144.
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    46. Caracciolo V, Young J, Gonzales D, Ni Y, Flowers SJ, Summer R, Waldman SA, Kim JK, Jung DY, Noh HL, Kim T, Blackshear PJ, O'Connell D, Bauer RC, Kallen CB. Myeloid-specific deletion of Zfp36 protects against insulin resistance and fatty liver in diet-induced obese mice. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E676-E693. PMID: 29509432.
      Citations:    
    47. Sherman W, Bartunek J, Dolatabadi D, Sanz-Ruiz R, Beleslin B, Wojakowski W, Heyndrickx G, Kimpalou JZ, Waldman SA, Laarman GJ, Seron A, Behfar A, Latere JP, Terzic A, Wijns W. First-in-Human Use of a Retention-Enhanced Catheter for Endomyocardial Cell Delivery. JACC Cardiovasc Interv. 2018 02 26; 11(4):412-414. PMID: 29471956.
      Citations:    
    48. Waldman SA, Terzic A. Process Improvement for Maximized Therapeutic Innovation Outcome. Clin Pharmacol Ther. 2018 Jan; 103(1):8-12. PMID: 29265398.
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    49. Kraft CL, Rappaport JA, Snook AE, Pattison AM, Lynch JP, Waldman SA. GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress. Oncotarget. 2017 Nov 28; 8(61):102923-102933. PMID: 29262534.
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    50. Li P, Wuthrick E, Rappaport JA, Kraft C, Lin JE, Marszalowicz G, Snook AE, Zhan T, Hyslop TM, Waldman SA. GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome. Cancer Res. 2017 09 15; 77(18):5095-5106. PMID: 28916678.
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    51. Li P, Lin JE, Snook AE, Waldman SA. ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice. Toxins (Basel). 2017 09 12; 9(9). PMID: 28895923.
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    52. Wei Q, Ye Z, Zhong X, Li L, Wang C, Myers RE, Palazzo JP, Fortuna D, Yan A, Waldman SA, Chen X, Posey JA, Basu-Mallick A, Jiang BH, Hou L, Shu J, Sun Y, Xing J, Li B, Yang H. Multiregion whole-exome sequencing of matched primary and metastatic tumors revealed genomic heterogeneity and suggested polyclonal seeding in colorectal cancer metastasis. Ann Oncol. 2017 Sep 01; 28(9):2135-2141. PMID: 28911083.
      Citations:    
    53. Waldman SA, Terzic A. Peer Review Certifies Quality and Innovation in Clinical Pharmacology & Therapeutics. Clin Pharmacol Ther. 2017 Sep; 102(3):373-377. PMID: 28782825.
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    54. Chervoneva I, Freydin B, Hyslop T, Waldman SA. Modeling qRT-PCR dynamics with application to cancer biomarker quantification. Stat Methods Med Res. 2018 09; 27(9):2581-2595. PMID: 28504051.
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    55. Aka AA, Rappaport JA, Pattison AM, Sato T, Snook AE, Waldman SA. Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer. Expert Rev Clin Pharmacol. 2017 May; 10(5):549-557. PMID: 28162021.
      Citations:    
    56. Weinberg DS, Lin JE, Foster NR, Della'Zanna G, Umar A, Seisler D, Kraft WK, Kastenberg DM, Katz LC, Limburg PJ, Waldman SA. Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention. Cancer Prev Res (Phila). 2017 Jun; 10(6):345-354. PMID: 28396341.
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    57. Xiang B, Baybutt TR, Berman-Booty L, Magee MS, Waldman SA, Alexeev VY, Snook AE. Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells. J Immunol. 2017 05 01; 198(9):3507-3514. PMID: 28341670.
      Citations:    
    58. Bartunek J, Terzic A, Davison BA, Filippatos GS, Radovanovic S, Beleslin B, Merkely B, Musialek P, Wojakowski W, Andreka P, Horvath IG, Katz A, Dolatabadi D, El Nakadi B, Arandjelovic A, Edes I, Seferovic PM, Obradovic S, Vanderheyden M, Jagic N, Petrov I, Atar S, Halabi M, Gelev VL, Shochat MK, Kasprzak JD, Sanz-Ruiz R, Heyndrickx GR, Nyolczas N, Legrand V, Gu?d?s A, Heyse A, Moccetti T, Fernandez-Aviles F, Jimenez-Quevedo P, Bayes-Genis A, Hernandez-Garcia JM, Ribichini F, Gruchala M, Waldman SA, Teerlink JR, Gersh BJ, Povsic TJ, Henry TD, Metra M, Hajjar RJ, Tendera M, Behfar A, Alexandre B, Seron A, Stough WG, Sherman W, Cotter G, Wijns W. Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial. Eur Heart J. 2017 Mar 01; 38(9):648-660. PMID: 28025189.
      Citations:    
    59. Waldman SA, Terzic A. Clinical Pharmacology & Therapeutics: Past, Present, and Future. Clin Pharmacol Ther. 2017 03; 101(3):300-303. PMID: 28194770.
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    60. Snook AE, Baybutt TR, Hyslop T, Waldman SA. Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope. Hum Gene Ther Methods. 2016 12; 27(6):238-250. PMID: 27903079.
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    61. Waldman SA, Terzic A. Managing Innovation to Maximize Value Along the Discovery-Translation-Application Continuum. Clin Pharmacol Ther. 2017 Jan; 101(1):8-12. PMID: 27869291.
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    62. Myers RE, Wolf T, Shwae P, Hegarty S, Peiper SC, Waldman SA. A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients. BMC Cancer. 2016 10 03; 16(1):766. PMID: 27716119.
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    63. Pattison AM, Merlino DJ, Blomain ES, Waldman SA. Guanylyl cyclase C signaling axis and colon cancer prevention. World J Gastroenterol. 2016 Sep 28; 22(36):8070-7. PMID: 27688649.
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    64. Pattison AM, Blomain ES, Merlino DJ, Wang F, Crissey MA, Kraft CL, Rappaport JA, Snook AE, Lynch JP, Waldman SA. Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins. Infect Immun. 2016 10; 84(10):3083-91. PMID: 27481254.
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    65. Magee MS, Kraft CL, Abraham TS, Baybutt TR, Marszalowicz GP, Li P, Waldman SA, Snook AE. GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity. Oncoimmunology. 2016; 5(10):e1227897. PMID: 27853651.
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    66. Blomain ES, Merlino DJ, Pattison AM, Snook AE, Waldman SA. Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer. Mol Pharmacol. 2016 Sep; 90(3):199-204. PMID: 27251363.
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    67. Kim GW, Lin JE, Snook AE, Aing AS, Merlino DJ, Li P, Waldman SA. Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity. Nutr Diabetes. 2016 May 23; 6:e211. PMID: 27214655.
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    68. Cantarin MP, Keith SW, Lin Z, Doria C, Frank AM, Maley WR, Ramirez C, Lallas CD, Shah A, Waldman SA, Falkner B. Association of Inflammation prior to Kidney Transplantation with Post-Transplant Diabetes Mellitus. Cardiorenal Med. 2016 Aug; 6(4):289-300. PMID: 27648010.
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    69. Blomain ES, Pattison AM, Waldman SA. GUCY2C ligand replacement to prevent colorectal cancer. Cancer Biol Ther. 2016 07 02; 17(7):713-8. PMID: 27104761.
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    70. Blomain ES, Waldman SA. Does obesity promote the development of colorectal cancer? Expert Rev Anticancer Ther. 2016 05; 16(5):465-7. PMID: 26943700.
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    71. Waldman SA, Terzic A. Big Data Transforms Discovery-Utilization Therapeutics Continuum. Clin Pharmacol Ther. 2016 Mar; 99(3):250-4. PMID: 26888297.
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    72. Lin JE, Colon-Gonzalez F, Blomain E, Kim GW, Aing A, Stoecker B, Rock J, Snook AE, Zhan T, Hyslop TM, Tomczak M, Blumberg RS, Waldman SA. Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis. Cancer Res. 2016 Jan 15; 76(2):339-46. PMID: 26773096.
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    73. Waldman SA. Editorial (Thematic Issue: Ferid Murad, at 80: A Legacy of Science, Medicine, and Mentorship). Curr Med Chem. 2016; 23(24):2556-2558. PMID: 27776470.
      Citations:    
    74. Waldman SA, Terzic A. Bioinnovation Enterprise: An engine driving breakthrough therapies. Clin Pharmacol Ther. 2016 Jan; 99(1):8-13. PMID: 26785918.
      Citations:    
    75. Krishnan V, Xu X, Kelly D, Snook A, Waldman SA, Mason RW, Jia X, Rajasekaran AK. CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia. Mol Pharm. 2015 Jun 01; 12(6):2101-11. PMID: 25898125.
      Citations:    
    76. Waldman SA, Terzic A. Companion diagnostics at the intersection of personalized medicine and healthcare delivery. Biomark Med. 2015; 9(1):1-3. PMID: 25605449.
      Citations:    
    77. Waldman SA, Terzic A. Clinical Pharmacology & Therapeutics: the next five years. Clin Pharmacol Ther. 2015 Jan; 97(1):2-6. PMID: 25670374.
      Citations:    
    78. Rodriguez E, Sakowski L, Hobson GM, Armani MH, Kreiger PA, Zhu Y, Waldman SA, Shaffer TH. Plp1 gene duplication inhibits airway responsiveness and induces lung inflammation. Pulm Pharmacol Ther. 2015 Feb; 30:22-31. PMID: 25445931.
      Citations:    
    79. Marszalowicz GP, Snook AE, Magee MS, Merlino D, Berman-Booty LD, Waldman SA. GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer. Oncotarget. 2014 Oct 15; 5(19):9460-71. PMID: 25294806.
      Citations:    
    80. Wilson C, Lin JE, Li P, Snook AE, Gong J, Sato T, Liu C, Girondo MA, Rui H, Hyslop T, Waldman SA. The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2014 Nov; 23(11):2328-37. PMID: 25304930.
      Citations:    
    81. Rodriguez E, Barthold JS, Kreiger PA, Armani MH, Wang J, Michelini KA, Wolfson MR, Boyce R, Barone CA, Zhu Y, Waldman SA, Shaffer TH. The orl rat is more responsive to methacholine challenge than wild type. Pulm Pharmacol Ther. 2014 Dec; 29(2):199-208. PMID: 25218882.
      Citations:    
    82. Witek ME, Snook AE, Lin JE, Blomain ES, Xiang B, Magee MS, Magee M, Waldman SA. A novel CDX2 isoform regulates alternative splicing. PLoS One. 2014; 9(8):e104293. PMID: 25101906.
      Citations:    
    83. Martinez Cantarin MP, Keith SW, Waldman SA, Falkner B. Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease. Nephrol Dial Transplant. 2014 Dec; 29(12):2268-77. PMID: 25049200.
      Citations:    
    84. Merlino DJ, Blomain ES, Aing AS, Waldman SA. Gut-Brain Endocrine Axes in Weight Regulation and Obesity Pharmacotherapy. J Clin Med. 2014 Jul 15; 3(3):763-94. PMID: 26237477.
      Citations:    
    85. Snook AE, Magee MS, Schulz S, Waldman SA. Selective antigen-specific CD4(+) T-cell, but not CD8(+) T- or B-cell, tolerance corrupts cancer immunotherapy. Eur J Immunol. 2014 Jul; 44(7):1956-66. PMID: 24771148.
      Citations:    
    86. Witek M, Blomain ES, Magee MS, Xiang B, Waldman SA, Snook AE. Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C. Int J Radiat Oncol Biol Phys. 2014 Apr 01; 88(5):1188-95. PMID: 24661671.
      Citations:    
    87. Nofziger C, Papaluca M, Terzic A, Waldman S, Paulmichl M. Policies to aid the adoption of personalized medicine. Nat Rev Drug Discov. 2014 Mar; 13(3):159-60. PMID: 24577385.
      Citations:    
    88. Waldman SA, Terzic A. Managing the innovation supply chain to maximize personalized medicine. Clin Pharmacol Ther. 2014 Feb; 95(2):113-8. PMID: 24448453.
      Citations:    
    89. Waldman SA, Terzic A. Molecular insights provide the critical path to disease mitigation. Clin Pharmacol Ther. 2014 Jan; 95(1):3-7. PMID: 24352148.
      Citations:    
    90. Bartunek J, Behfar A, Dolatabadi D, Vanderheyden M, Ostojic M, Dens J, El Nakadi B, Banovic M, Beleslin B, Vrolix M, Legrand V, Vrints C, Vanoverschelde JL, Crespo-Diaz R, Homsy C, Tendera M, Waldman S, Wijns W, Terzic A. Reply: The C-CURE Randomized Clinical Trial (Cardiopoietic stem Cell therapy in heart failURE). J Am Coll Cardiol. 2013 Dec 24; 62(25):2454-2456. PMID: 24355591.
      Citations:    
    91. Ganesh SK, Arnett DK, Assimes TL, Assimes TL, Basson CT, Chakravarti A, Ellinor PT, Engler MB, Goldmuntz E, Herrington DM, Hershberger RE, Hong Y, Johnson JA, Kittner SJ, McDermott DA, Meschia JF, Mestroni L, O'Donnell CJ, Psaty BM, Vasan RS, Ruel M, Shen WK, Terzic A, Waldman SA. Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association. Circulation. 2013 Dec 24; 128(25):2813-51. PMID: 24297835.
      Citations:    
    92. Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Br?er S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M. The Concise Guide to PHARMACOLOGY 2013/14: overview. Br J Pharmacol. 2013 Dec; 170(8):1449-58. PMID: 24528237.
      Citations:    
    93. Kim GW, Lin JE, Blomain ES, Waldman SA. Antiobesity pharmacotherapy: new drugs and emerging targets. Clin Pharmacol Ther. 2014 Jan; 95(1):53-66. PMID: 24105257.
      Citations:    
    94. Gibbons AV, Lin JE, Kim GW, Marszalowicz GP, Li P, Stoecker BA, Blomain ES, Rattan S, Snook AE, Schulz S, Waldman SA. Intestinal GUCY2C prevents TGF-? secretion coordinating desmoplasia and hyperproliferation in colorectal cancer. Cancer Res. 2013 Nov 15; 73(22):6654-66. PMID: 24085786.
      Citations:    
    95. Blomain ES, Lin JE, Kraft CL, Trela UT, Rock JM, Aing AS, Snook AE, Waldman SA. Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis. Expert Rev Clin Pharmacol. 2013 Sep; 6(5):557-64. PMID: 23971873.
      Citations:    
    96. Waldman SA, van der Graaf PH, Terzic A. Systems approaches evolve clinical pharmacology. CPT Pharmacometrics Syst Pharmacol. 2013 Aug 21; 2:e68. PMID: 23965784.
      Citations:    
    97. Xiang B, Snook AE, Magee MS, Waldman SA. Colorectal cancer immunotherapy. Discov Med. 2013 May; 15(84):301-8. PMID: 23725603.
      Citations:    
    98. Kim GW, Lin JE, Blomain ES, Waldman SA. New advances in models and strategies for developing anti-obesity drugs. Expert Opin Drug Discov. 2013 Jun; 8(6):655-71. PMID: 23621300.
      Citations:    
    99. Blomain ES, Dirhan DA, Valentino MA, Kim GW, Waldman SA. Mechanisms of Weight Regain following Weight Loss. ISRN Obes. 2013; 2013:210524. PMID: 24533218.
      Citations:    
    100. Bartunek J, Behfar A, Dolatabadi D, Vanderheyden M, Ostojic M, Dens J, El Nakadi B, Banovic M, Beleslin B, Vrolix M, Legrand V, Vrints C, Vanoverschelde JL, Crespo-Diaz R, Homsy C, Tendera M, Waldman S, Wijns W, Terzic A. Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics. J Am Coll Cardiol. 2013 Jun 11; 61(23):2329-38. PMID: 23583246.
      Citations:    
    101. Waldman SA, Terzic A. Systems-based discovery advances drug development. Clin Pharmacol Ther. 2013 Apr; 93(4):285-7. PMID: 23511779.
      Citations:    
    102. Avital I, Summers TA, Steele SR, Waldman S, Nissan A, Bilchik AJ, Protic M, Man YG, Br?cher BL, Stojadinovic A. Colorectal cancer stem cells as biomarkers: where it all starts? J Surg Oncol. 2013 Jun; 107(8):791-3. PMID: 23512573.
      Citations:    
    103. Avital I, Langan RC, Summers TA, Steele SR, Waldman SA, Backman V, Yee J, Nissan A, Young P, Womeldorph C, Mancusco P, Mueller R, Noto K, Grundfest W, Bilchik AJ, Protic M, Daumer M, Eberhardt J, Man YG, Br?cher BL, Stojadinovic A. Evidence-based Guidelines for Precision Risk Stratification-Based Screening (PRSBS) for Colorectal Cancer: Lessons learned from the US Armed Forces: Consensus and Future Directions. J Cancer. 2013; 4(3):172-92. PMID: 23459409.
      Citations:    
    104. Hyslop T, Waldman SA. Molecular staging of node negative patients with colorectal cancer. J Cancer. 2013; 4(3):193-9. PMID: 23459453.
      Citations:    
    105. Snook AE, Waldman SA. Advances in cancer immunotherapy. Discov Med. 2013 Feb; 15(81):120-5. PMID: 23449114.
      Citations:    
    106. Waldman SA, Terzic A. Translational medicine individualizes healthcare discovery, development and delivery. Foreword. Biomark Med. 2013 Feb; 7(1):1-3. PMID: 23387479.
      Citations:    
    107. Magee MS, Snook AE, Marszalowicz GP, Waldman SA. Immunotherapeutic strategies to target prognostic and predictive markers of cancer. Biomark Med. 2013 Feb; 7(1):23-35. PMID: 23387482.
      Citations:    
    108. Hyslop T, Waldman SA. Guanylyl cyclase C as a biomarker in colorectal cancer. Biomark Med. 2013 Feb; 7(1):159-67. PMID: 23387497.
      Citations:    
    109. Kim GW, Lin JE, Waldman SA. GUCY2C: at the intersection of obesity and cancer. Trends Endocrinol Metab. 2013 Apr; 24(4):165-73. PMID: 23375388.
      Citations:    
    110. Martinez Cantarin MP, Waldman SA, Doria C, Frank AM, Maley WR, Ramirez CB, Keith SW, Falkner B. The adipose tissue production of adiponectin is increased in end-stage renal disease. Kidney Int. 2013 Mar; 83(3):487-94. PMID: 23283133.
      Citations:    
    111. Waldman SA, Terzic A. Information hierarchies optimize patient-centered solutions. Clin Pharmacol Ther. 2013 Jan; 93(1):3-7. PMID: 23241831.
      Citations:    
    112. Krishnan V, Xu X, Barwe SP, Yang X, Czymmek K, Waldman SA, Mason RW, Jia X, Rajasekaran AK. Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine. Mol Pharm. 2013 Jun 03; 10(6):2199-210. PMID: 23194373.
      Citations:    
    113. Waldman SA, Terzic A. Advancing pharmacometrics and systems pharmacology. Clin Pharmacol Ther. 2012 Nov; 92(5):535-7. PMID: 23085873.
      Citations:    
    114. Colon-Gonzalez F, Kim GW, Lin JE, Valentino MA, Waldman SA. Obesity pharmacotherapy: what is next? Mol Aspects Med. 2013 Feb; 34(1):71-83. PMID: 23103610.
      Citations:    
    115. Gong JP, Schulz S, Hyslop T, Waldman SA. GUCY2C molecular staging personalizes colorectal cancer patient management. Biomark Med. 2012 Jun; 6(3):339-48. PMID: 22731908.
      Citations:    
    116. Mejia A, Schulz S, Hyslop T, Weinberg DS, Waldman SA. Molecular staging individualizing cancer management. J Surg Oncol. 2012 Apr 01; 105(5):468-74. PMID: 22441898.
      Citations:    
    117. Waldman SA, Terzic A. The value proposition of molecular medicine. Clin Transl Sci. 2012 Feb; 5(1):108-10. PMID: 22376267.
      Citations:    
    118. Lin JE, Snook AE, Li P, Stoecker BA, Kim GW, Magee MS, Garcia AV, Valentino MA, Hyslop T, Schulz S, Waldman SA. GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity. PLoS One. 2012; 7(2):e31686. PMID: 22384056.
      Citations:    
    119. Hyslop T, Weinberg DS, Schulz S, Barkun A, Waldman SA. Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer. J Surg Oncol. 2012 Jul 01; 106(1):24-30. PMID: 22252429.
      Citations:    
    120. Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperri?re D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, H?ligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW. The transcription factor encyclopedia. Genome Biol. 2012; 13(3):R24. PMID: 22458515.
      Citations:    
    121. Waldman SA, Terzic A. Knowledge cycle transforms therapeutic innovation. Clin Pharmacol Ther. 2012 Jan; 91(1):3-8. PMID: 22179622.
      Citations:    
    122. Waldman SA, Terzic A. Patient-centric clinical pharmacology advances the path to personalized medicine. Biomark Med. 2011 Dec; 5(6):697-700. PMID: 22103605.
      Citations:    
    123. Snook AE, Magee MS, Waldman SA. GUCY2C-targeted cancer immunotherapy: past, present and future. Immunol Res. 2011 Dec; 51(2-3):161-9. PMID: 22038530.
      Citations:    
    124. Snook AE, Magee MS, Marszalowicz GP, Schulz S, Waldman SA. Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C. Cancer Immunol Immunother. 2012 May; 61(5):713-23. PMID: 22057677.
      Citations:    
    125. Waldman SA, Terzic A. Widening the path to personalized medicine. Clin Transl Sci. 2011 Oct; 4(5):392-4. PMID: 22029815.
      Citations:    
    126. Waldman SA, Terzic A. Cardiovascular health: the global challenge. Clin Pharmacol Ther. 2011 Oct; 90(4):483-5. PMID: 21934716.
      Citations:    
    127. Hyslop T, Weinberg DS, Schulz S, Barkun A, Waldman SA. Occult tumor burden contributes to racial disparities in stage-specific colorectal cancer outcomes. Cancer. 2012 May 01; 118(9):2532-40. PMID: 21887684.
      Citations:    
    128. Valentino MA, Lin JE, Snook AE, Li P, Kim GW, Marszalowicz G, Magee MS, Hyslop T, Schulz S, Waldman SA. A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. J Clin Invest. 2011 Sep; 121(9):3578-88. PMID: 21865642.
      Citations:    
    129. Crist RC, Roth JJ, Waldman SA, Buchberg AM. A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer. PLoS One. 2011; 6(8):e23665. PMID: 21858198.
      Citations:    
    130. Zuzga DS, Pelta-Heller J, Li P, Bombonati A, Waldman SA, Pitari GM. Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer. Int J Cancer. 2012 Jun 01; 130(11):2539-48. PMID: 21702043.
      Citations:    
    131. Waldman SA, Hohl RJ, Kearns GL, Swan SJ, Terzic A. Clinical pharmacology as a foundation for translational science. Clin Pharmacol Ther. 2011 Jul; 90(1):10-3. PMID: 21691266.
      Citations:    
    132. Terzic A, Waldman S. Chronic diseases: the emerging pandemic. Clin Transl Sci. 2011 Jun; 4(3):225-6. PMID: 21707955.
      Citations:    
    133. Waldman SA, Terzic A. Clinical pharmacology at the core of translational science. Expert Rev Clin Pharmacol. 2011 May; 4(3):303-5. PMID: 22114776.
      Citations:    
    134. Goldberg BB, Merton DA, Liu JB, Forsberg F, Zhang K, Thakur M, Schulz S, Schanche R, Murphy GF, Waldman SA. Contrast-enhanced ultrasound imaging of sentinel lymph nodes after peritumoral administration of Sonazoid in a melanoma tumor animal model. J Ultrasound Med. 2011 Apr; 30(4):441-53. PMID: 21460143.
      Citations:    
    135. Waldman SA, Terzic A. Bionic technologies transforming the science of healthcare delivery. Clin Transl Sci. 2011 Apr; 4(2):84-6. PMID: 21463492.
      Citations:    
    136. Kim GW, Lin JE, Valentino MA, Colon-Gonzalez F, Waldman SA. Regulation of appetite to treat obesity. Expert Rev Clin Pharmacol. 2011 Mar; 4(2):243-59. PMID: 21666781.
      Citations:    
    137. Hyslop T, Weinberg DS, Schulz S, Barkun A, Waldman SA. Occult tumor burden predicts disease recurrence in lymph node-negative colorectal cancer. Clin Cancer Res. 2011 May 15; 17(10):3293-303. PMID: 21307149.
      Citations:    
    138. Waldman SA, Terzic A. Clinical translational science 2020: disruptive innovation redefines the discovery-application enterprise. Clin Transl Sci. 2011 Feb; 4(1):69-71. PMID: 21348959.
      Citations:    
    139. Terzic A, Waldman SA. Translational medicine: path to personalized and public health. Biomark Med. 2010 Dec; 4(6):787-90. PMID: 21133696.
      Citations:    
    140. Waldman SA, Terzic A. Clinical and translational science: from bench-bedside to global village. Clin Transl Sci. 2010 Oct; 3(5):254-7. PMID: 20973923.
      Citations:    
    141. Valentino MA, Colon-Gonzalez F, Lin JE, Waldman SA. Current trends in targeting the hormonal regulation of appetite and energy balance to treat obesity. Expert Rev Endocrinol Metab. 2010 Sep 01; 5(5):765-783. PMID: 21297878.
      Citations:    
    142. Lin JE, Valentino M, Marszalowicz G, Magee MS, Li P, Snook AE, Stoecker BA, Chang C, Waldman SA. Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics. Toxins (Basel). 2010 08; 2(8):2028-54. PMID: 22069671.
      Citations:    
    143. Li P, Waldman SA. Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis. Cancer Biol Ther. 2010 Aug 01; 10(3):211-8. PMID: 20592492.
      Citations:    
    144. Waldman SA, Terzic A. Molecular therapy drives patient-centric health care paradigms. Clin Transl Sci. 2010 Aug; 3(4):170-1. PMID: 20718817.
      Citations:    
    145. Valentino MA, Terzic A, Waldman SA. Sizing up pharmacotherapy for obesity. Clin Transl Sci. 2010 Jun; 3(3):123-5. PMID: 20590683.
      Citations:    
    146. Waldman SA, Terzic A. Molecular therapeutics from knowledge to delivery. Clin Pharmacol Ther. 2010 Jun; 87(6):619-23. PMID: 20485312.
      Citations:    
    147. Chervoneva I, Li Y, Schulz S, Croker S, Wilson C, Waldman SA, Hyslop T. Selection of optimal reference genes for normalization in quantitative RT-PCR. BMC Bioinformatics. 2010 May 14; 11:253. PMID: 20470420.
      Citations:    
    148. Valentino MA, Lin JE, Waldman SA. Central and peripheral molecular targets for antiobesity pharmacotherapy. Clin Pharmacol Ther. 2010 Jun; 87(6):652-62. PMID: 20445536.
      Citations:    
    149. Bharucha AE, Waldman SA. Taking a lesson from microbial diarrheagenesis in the management of chronic constipation. Gastroenterology. 2010 Mar; 138(3):813-7. PMID: 20114092.
      Citations:    
    150. Mejia A, Schulz S, Hyslop T, Weinberg DS, Waldman SA. Molecular staging estimates occult tumor burden in colorectal cancer. Adv Clin Chem. 2010; 52:19-39. PMID: 21275338.
      Citations:    
    151. Waldman SA, Kraft WK, Nelson TJ, Terzic A. Clinical pharmacology: a paradigm for individualized medicine. Biomark Med. 2009 Dec; 3(6):679-84. PMID: 20477706.
      Citations:    
    152. Waldman SA, Kraft WK, Nelson TJ, Terzic A. Experimental therapeutics: a paradigm for personalized medicine. Clin Transl Sci. 2009 Dec; 2(6):436-8. PMID: 20443936.
      Citations:    
    153. Mejia A, Schulz S, Hyslop T, Weinberg DS, Waldman SA. GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patients. Expert Rev Mol Diagn. 2009 Nov; 9(8):777-85. PMID: 19895223.
      Citations:    
    154. Li P, Lin JE, Schulz S, Pitari GM, Waldman SA. Can colorectal cancer be prevented or treated by oral hormone replacement therapy? Curr Mol Pharmacol. 2009 Nov; 2(3):285-92. PMID: 20021465.
      Citations:    
    155. Park JY, Kirn TJ, Artis D, Waldman SA, Kricka LJ. Chemiluminescence-based detection of gastrointestinal malignancies. Luminescence. 2010 Nov-Dec; 25(6):463-5. PMID: 19827005.
      Citations:    
    156. Winn B, Tavares R, Matoso A, Noble L, Fanion J, Waldman SA, Resnick MB. Expression of the intestinal biomarkers Guanylyl cyclase C and CDX2 in poorly differentiated colorectal carcinomas. Hum Pathol. 2010 Jan; 41(1):123-8. PMID: 19800103.
      Citations:    
    157. Lin JE, Li P, Snook AE, Schulz S, Dasgupta A, Hyslop TM, Gibbons AV, Marszlowicz G, Pitari GM, Waldman SA. The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. Gastroenterology. 2010 Jan; 138(1):241-54. PMID: 19737566.
      Citations:    
    158. Ciocca V, Bombonati A, Palazzo JP, Schulz S, Waldman SA. Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms. Histopathology. 2009 Aug; 55(2):182-8. PMID: 19694825.
      Citations:    
    159. Gong L, Debruyne PR, Witek M, Nielsen K, Snook A, Lin JE, Bombonati A, Palazzo J, Schulz S, Waldman SA. Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis. Clin Transl Sci. 2009 Aug; 2(4):286-93. PMID: 20443907.
      Citations:    
    160. Li P, Lin JE, Marszlowicz GP, Valentino MA, Chang C, Schulz S, Pitari GM, Waldman SA. GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome? Drug News Perspect. 2009 Jul-Aug; 22(6):313-8. PMID: 19771320.
      Citations:    
    161. Waldman SA, Terzic A. Applications of microRNA in cancer: Exploring the advantages of miRNA. Clin Transl Sci. 2009 Jun; 2(3):248-9. PMID: 20443899.
      Citations:    
    162. Lin JE, Li P, Pitari GM, Schulz S, Waldman SA. Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target. Future Oncol. 2009 May; 5(4):509-22. PMID: 19450179.
      Citations:    
    163. Snook AE, Li P, Stafford BJ, Faul EJ, Huang L, Birbe RC, Bombonati A, Schulz S, Schnell MJ, Eisenlohr LC, Waldman SA. Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease. Cancer Res. 2009 Apr 15; 69(8):3537-44. PMID: 19351847.
      Citations:    
    164. Waldman SA, Terzic A. Translational medicine in the era of health care reform. Clin Transl Sci. 2009 Apr; 2(2):96-7. PMID: 20443877.
      Citations:    
    165. Lubbe WJ, Zuzga DS, Zhou Z, Fu W, Pelta-Heller J, Muschel RJ, Waldman SA, Pitari GM. Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9. Cancer Res. 2009 Apr 15; 69(8):3529-36. PMID: 19336567.
      Citations:    
    166. Waldman SA, Terzic A. A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer. FEBS J. 2009 Apr; 276(8):2157-64. PMID: 19250312.
      Citations:    
    167. Waldman SA, Hyslop T, Schulz S, Barkun A, Nielsen K, Haaf J, Bonaccorso C, Li Y, Weinberg DS. Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer. JAMA. 2009 Feb 18; 301(7):745-52. PMID: 19224751.
      Citations:    
    168. Waldman SA, Terzic A. Molecular diagnostics. At the nexus of individualized medicine, health care delivery, and public policy. Clin Transl Sci. 2009 Feb; 2(1):6-8. PMID: 20443861.
      Citations:    
    169. Chang C, Marszlowicz G, Waldman Z, Li P, Snook AE, Lin JE, Schulz S, Waldman SA. Guanylyl cyclase C as a biomarker for targeted imaging and therapy of metastatic colorectal cancer. Biomark Med. 2009 Feb; 3(1):33-45. PMID: 20477494.
      Citations:    
    170. Waldman SA. Transitioning biomarkers into the clinic. Expert Rev Clin Pharmacol. 2009 Jan; 2(1):9-13. PMID: 24422768.
      Citations:    
    171. Snook AE, Waldman SA. CANCER MUCOSA ANTIGENS A NOVEL PARADIGM IN CANCER IMMUNOTHERAPEUTICS. Bioforum Eur. 2009; 3:14-16. PMID: 26855637.
      Citations:    
    172. Snook AE, Huang L, Schulz S, Eisenlohr LC, Waldman SA. Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens. Clin Transl Sci. 2008 Dec; 1(3):263-4. PMID: 19956776.
      Citations:    
    173. Waldman SA, Terzic A. The roadmap to personalized medicine. Clin Transl Sci. 2008 Sep; 1(2):93. PMID: 20443827.
      Citations:    
    174. Li P, Schulz S, Pitari GM, Waldman SA. Sex modulates intestinal transformation by the tumor-suppressor GCC. Clin Transl Sci. 2008 Sep; 1(2):146-50. PMID: 20443837.
      Citations:    
    175. Li P, Schulz S, Pitari GM, Waldman SA. Sex modulates intestinal transformation by the tumor-suppressor GCC. Clin Transl Sci. 2008 Sep; 1(2):150. PMID: 20443838.
      Citations:    
    176. Li P, Lin JE, Snook AE, Gibbons AV, Zuzga DS, Schulz S, Pitari GM, Waldman SA. Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy. Clin Transl Sci. 2008 Sep; 1(2):163-7. PMID: 19727435.
      Citations:    
    177. Waldman SA, Terzic A. Pharmacoeconomics in the era of individualized medicine. Clin Pharmacol Ther. 2008 Aug; 84(2):179-82. PMID: 18679176.
      Citations:    
    178. Snook AE, Stafford BJ, Li P, Tan G, Huang L, Birbe R, Schulz S, Schnell MJ, Thakur M, Rothstein JL, Eisenlohr LC, Waldman SA. Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity. J Natl Cancer Inst. 2008 Jul 02; 100(13):950-61. PMID: 18577748.
      Citations:    
    179. Pitari GM, Lin JE, Shah FJ, Lubbe WJ, Zuzga DS, Li P, Schulz S, Waldman SA. Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells. Carcinogenesis. 2008 Aug; 29(8):1601-7. PMID: 18566015.
      Citations:    
    180. Waldman SA, Terzic A. MicroRNA signatures as diagnostic and therapeutic targets. Clin Chem. 2008 Jun; 54(6):943-4. PMID: 18509012.
      Citations:    
    181. Waldman SA, Terzic A. Clinical and translational sciences: at the intersection of molecular and individualized medicine. Clin Transl Sci. 2008 May; 1(1):6-8. PMID: 20443812.
      Citations:    
    182. Waldman SA, Terzic A. Therapeutic targeting: a crucible for individualized medicine. Clin Pharmacol Ther. 2008 May; 83(5):651-4. PMID: 18425084.
      Citations:    
    183. Plesa G, Snook AE, Waldman SA, Eisenlohr LC. Derivation and fluidity of acutely induced dysfunctional CD8+ T cells. J Immunol. 2008 Apr 15; 180(8):5300-8. PMID: 18390711.
      Citations:    
    184. Waldman SA, Terzic A. Therapeutic burden in cancer revealed by molecular staging. Biomark Med. 2008 Feb; 2(1):1-3. PMID: 20477357.
      Citations:    
    185. Tian X, Michal AM, Li P, Wolfe HR, Waldman SA, Wickstrom E. STa peptide analogs for probing guanylyl cyclase C. Biopolymers. 2008; 90(5):713-23. PMID: 18615494.
      Citations:    
    186. Kraft WK, Waldman SA. Bridging the therapeutic continuum of drug development, regulation and use. Expert Rev Clin Pharmacol. 2008 Jan; 1(1):1-3. PMID: 24410503.
      Citations:    
    187. Larusso J, Waldman SA, Kraft WK. Aprepitant for the prevention of nausea and vomiting associated with chemotherapy and postoperative recovery. Expert Rev Clin Pharmacol. 2008 Jan; 1(1):27-37. PMID: 24410507.
      Citations:    
    188. Chervoneva I, Li Y, Iglewicz B, Waldman S, Hyslop T. Relative quantification based on logistic models for individual polymerase chain reactions. Stat Med. 2007 Dec 30; 26(30):5596-611. PMID: 17968873.
      Citations:    
    189. Li P, Lin JE, Chervoneva I, Schulz S, Waldman SA, Pitari GM. Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine. Am J Pathol. 2007 Dec; 171(6):1847-58. PMID: 17974601.
      Citations:    
    190. Waldman SA, Terzic A. Individualized medicine and the imperative of global health. Clin Pharmacol Ther. 2007 Nov; 82(5):479-83. PMID: 17952097.
      Citations:    
    191. Waldman SA, Terzic MR, Terzic A. Molecular medicine hones therapeutic arts to science. Clin Pharmacol Ther. 2007 Oct; 82(4):343-7. PMID: 17851568.
      Citations:    
    192. Snook AE, Eisenlohr LC, Rothstein JL, Waldman SA. Cancer mucosa antigens as a novel immunotherapeutic class of tumor-associated antigen. Clin Pharmacol Ther. 2007 Dec; 82(6):734-9. PMID: 17898707.
      Citations:    
    193. Terzic A, Moore RL, Waldman SA. Acquired and innate cardioprotection. J Appl Physiol (1985). 2007 Oct; 103(4):1436-7. PMID: 17690193.
      Citations:    
    194. Pitari GM, Li P, Lin JE, Zuzga D, Gibbons AV, Snook AE, Schulz S, Waldman SA. The paracrine hormone hypothesis of colorectal cancer. Clin Pharmacol Ther. 2007 Oct; 82(4):441-7. PMID: 17687268.
      Citations:    
    195. Li P, Schulz S, Bombonati A, Palazzo JP, Hyslop TM, Xu Y, Baran AA, Siracusa LD, Pitari GM, Waldman SA. Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity. Gastroenterology. 2007 Aug; 133(2):599-607. PMID: 17681179.
      Citations:    
    196. Waldman S, Terzic A. Targeted diagnostics and therapeutics for individualized patient management. Biomark Med. 2007 Jun; 1(1):3-8. PMID: 20477454.
      Citations:    
    197. Snook AE, Stafford BJ, Eisenlohr LC, Rothstein JL, Waldman SA. Mucosally restricted antigens as novel immunological targets for antitumor therapy. Biomark Med. 2007 Jun; 1(1):187-202. PMID: 20477468.
      Citations:    
    198. Waldman SA, Terzic A. Translating MicroRNA discovery into clinical biomarkers in cancer. JAMA. 2007 May 02; 297(17):1923-5. PMID: 17473304.
      Citations:    
    199. Gong L, Greenberg HE, Perhach JL, Waldman SA, Kraft WK. The pharmacokinetics of taurolidine metabolites in healthy volunteers. J Clin Pharmacol. 2007 Jun; 47(6):697-703. PMID: 17395893.
      Citations:    
    200. Fortina P, Kricka LJ, Graves DJ, Park J, Hyslop T, Tam F, Halas N, Surrey S, Waldman SA. Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer. Trends Biotechnol. 2007 Apr; 25(4):145-52. PMID: 17316852.
      Citations:    
    201. Wilson CL, Schultz S, Waldman SA. Where medicine, business, and public policy intersect. Biotechnol Healthc. 2007 Feb; 4(1):33-42. PMID: 23397413.
      Citations:    
    202. Wilson C, Schulz S, Waldman SA. Biomarker development, commercialization, and regulation: individualization of medicine lost in translation. Clin Pharmacol Ther. 2007 Feb; 81(2):153-5. PMID: 17259939.
      Citations:    
    203. de Godoy MA, Patel CA, Waldman SA, Katsuki M, Regan RF, Rattan S. H-ras inhibits RhoA/ROCK leading to a decrease in the basal tone in the internal anal sphincter. Gastroenterology. 2007 Apr; 132(4):1401-9. PMID: 17408635.
      Citations:    
    204. Waldman SA, Christensen NB, Moore JE, Terzic A. Clinical pharmacology: the science of therapeutics. Clin Pharmacol Ther. 2007 Jan; 81(1):3-6. PMID: 17185986.
      Citations:    
    205. Waldman SA, Fortina P, Surrey S, Hyslop T, Kricka LJ, Graves DJ. Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells. Future Oncol. 2006 Dec; 2(6):705-16. PMID: 17155897.
      Citations:    
    206. Schulz S, Hyslop T, Haaf J, Bonaccorso C, Nielsen K, Witek ME, Birbe R, Palazzo J, Weinberg D, Waldman SA. A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer. Clin Cancer Res. 2006 Aug 01; 12(15):4545-52. PMID: 16899600.
      Citations:    
    207. Pitari GM, Li T, Baksh RI, Waldman SA. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells. Mol Cancer Ther. 2006 May; 5(5):1190-6. PMID: 16731751.
      Citations:    
    208. Debruyne PR, Witek M, Gong L, Birbe R, Chervoneva I, Jin T, Domon-Cell C, Palazzo JP, Freund JN, Li P, Pitari GM, Schulz S, Waldman SA. Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells. Gastroenterology. 2006 Apr; 130(4):1191-206. PMID: 16618413.
      Citations:    
    209. Kandel RA, Grynpas M, Pilliar R, Lee J, Wang J, Waldman S, Zalzal P, Hurtig M. Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model. Biomaterials. 2006 Aug; 27(22):4120-31. PMID: 16564568.
      Citations:    
    210. Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM. Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer. Clin Cancer Res. 2006 Mar 15; 12(6):1876-82. PMID: 16551873.
      Citations:    
    211. Majumdar AK, Howard L, Goldberg MR, Hickey L, Constanzer M, Rothenberg PL, Crumley TM, Panebianco D, Bradstreet TE, Bergman AJ, Waldman SA, Greenberg HE, Butler K, Knops A, De Lepeleire I, Michiels N, Petty KJ. Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers. J Clin Pharmacol. 2006 Mar; 46(3):291-300. PMID: 16490805.
      Citations:    
    212. Witek ME, Nielsen K, Walters R, Hyslop T, Palazzo J, Schulz S, Waldman SA. The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas. Clin Cancer Res. 2005 Dec 15; 11(24 Pt 1):8549-56. PMID: 16361536.
      Citations:    
    213. Pitari GM, Baksh RI, Harris DM, Li P, Kazerounian S, Waldman SA. Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins. Cancer Res. 2005 Dec 01; 65(23):11129-35. PMID: 16322263.
      Citations:    
    214. Chervoneva I, Hyslop T, Iglewicz B, Johns L, Wolfe HR, Schulz S, Leong E, Waldman S. Statistical algorithm for assuring similar efficiency in standards and samples for absolute quantification by real-time reverse transcription polymerase chain reaction. Anal Biochem. 2006 Jan 15; 348(2):198-208. PMID: 16336939.
      Citations:    
    215. Frick GS, Pitari GM, Weinberg DS, Hyslop T, Schulz S, Waldman SA. Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer. Expert Rev Mol Diagn. 2005 Sep; 5(5):701-13. PMID: 16149873.
      Citations:    
    216. Kazerounian S, Pitari GM, Shah FJ, Frick GS, Madesh M, Ruiz-Stewart I, Schulz S, Hajn?czky G, Waldman SA. Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins. J Pharmacol Exp Ther. 2005 Sep; 314(3):1013-22. PMID: 15937149.
      Citations:    
    217. Birbe R, Palazzo JP, Walters R, Weinberg D, Schulz S, Waldman SA. Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract. Hum Pathol. 2005 Feb; 36(2):170-9. PMID: 15754294.
      Citations:    
    218. Tian X, Aruva MR, Wolfe HR, Qin W, Sauter ER, Thakur ML, Waldman SA, Wickstrom E. Tumor-targeting peptide-PNA-peptide chimeras for imaging overexpressed oncogene mRNAs. Nucleosides Nucleotides Nucleic Acids. 2005; 24(5-7):1085-91. PMID: 16248097.
      Citations:    
    219. Stone JA, Migoya EM, Hickey L, Winchell GA, Deutsch PJ, Ghosh K, Freeman A, Bi S, Desai R, Dilzer SC, Lasseter KC, Kraft WK, Greenberg H, Waldman SA. Potential for interactions between caspofungin and nelfinavir or rifampin. Antimicrob Agents Chemother. 2004 Nov; 48(11):4306-14. PMID: 15504857.
      Citations:    
    220. Waldman SA. Markers of cell cycle-mediated drug resistance and prognosis of patients receiving preoperative combined modality therapy for rectal cancer. Ann Surg Oncol. 2004 Nov; 11(11):949-50. PMID: 15525820.
      Citations:    
    221. Agrawal NG, Matthews CZ, Mazenko RS, Woolf EJ, Porras AG, Chen X, Miller JL, Michiels N, Wehling M, Schultz A, Gottlieb AB, Kraft WK, Greenberg HE, Waldman SA, Curtis SP, Gottesdiener KM. The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity. J Clin Pharmacol. 2004 Oct; 44(10):1125-31. PMID: 15342613.
      Citations:    
    222. Wong BK, Sahly Y, Mistry G, Waldman S, Musson D, Majumdar A, Xu X, Yu S, Lin JH, Singh R, Holland S. Comparative disposition of [14C]ertapenem, a novel carbapenem antibiotic, in rat, monkey and man. Xenobiotica. 2004 Apr; 34(4):379-89. PMID: 15268982.
      Citations:    
    223. Kraft WK, McCrea JB, Winchell GA, Carides A, Lowry R, Woolf EJ, Kusma SE, Deutsch PJ, Greenberg HE, Waldman SA. Indinavir and rifabutin drug interactions in healthy volunteers. J Clin Pharmacol. 2004 Mar; 44(3):305-13. PMID: 14973305.
      Citations:    
    224. Tiyyagura SR, Kazerounian S, Schulz S, Waldman SA, Pitari GM. Reciprocal regulation and integration of signaling by intracellular calcium and cyclic GMP. Vitam Horm. 2004; 69:69-94. PMID: 15196879.
      Citations:    
    225. Gong L, Pitari GM, Schulz S, Waldman SA. Nitric oxide signaling: systems integration of oxygen balance in defense of cell integrity. Curr Opin Hematol. 2004 Jan; 11(1):7-14. PMID: 14676622.
      Citations:    
    226. Kraft WK, Steiger B, Beussink D, Quiring JN, Fitzgerald N, Greenberg HE, Waldman SA. The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers. J Clin Pharmacol. 2004 Jan; 44(1):67-72. PMID: 14681343.
      Citations:    
    227. Lasseter KC, Dilzer SC, Vargas R, Waldman S, Noveck RJ. Pharmacokinetics and safety of ebastine in patients with impaired hepatic function compared with healthy volunteers: a phase I open-label study. Clin Pharmacokinet. 2004; 43(2):121-9. PMID: 14748620.
      Citations:    
    228. Ruiz-Stewart I, Tiyyagura SR, Lin JE, Kazerounian S, Pitari GM, Schulz S, Martin E, Murad F, Waldman SA. Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism. Proc Natl Acad Sci U S A. 2004 Jan 06; 101(1):37-42. PMID: 14684830.
      Citations:    
    229. Veronese ML, Gillen LP, Dorval EP, Hauck WW, Waldman SA, Greenberg HE. Effect of mibefradil on CYP3A4 in vivo. J Clin Pharmacol. 2003 Oct; 43(10):1091-100. PMID: 14517191.
      Citations:    
    230. Burke J, Kraft WK, Greenberg HE, Gleave M, Pitari GM, VanBuren S, Wagner JA, Waldman SA. Relationship of arachidonic acid concentration to cyclooxygenase-dependent human platelet aggregation. J Clin Pharmacol. 2003 Sep; 43(9):983-9. PMID: 12971030.
      Citations:    
    231. Veronese ML, Gillen LP, Burke JP, Dorval EP, Hauck WW, Pequignot E, Waldman SA, Greenberg HE. Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice. J Clin Pharmacol. 2003 Aug; 43(8):831-9. PMID: 12953340.
      Citations:    
    232. Debruyne PR, Waldman SA, Schulz S. Pathological staging and therapy of oesophageal and gastric cancer. Expert Opin Pharmacother. 2003 Jul; 4(7):1083-96. PMID: 12831335.
      Citations:    
    233. Dallob A, Hawkey CJ, Greenberg H, Wight N, De Schepper P, Waldman S, Wong P, DeTora L, Gertz B, Agrawal N, Wagner J, Gottesdiener K. Characterization of etoricoxib, a novel, selective COX-2 inhibitor. J Clin Pharmacol. 2003 Jun; 43(6):573-85. PMID: 12817520.
      Citations:    
    234. Blum RA, Majumdar A, McCrea J, Busillo J, Orlowski LH, Panebianco D, Hesney M, Petty KJ, Goldberg MR, Murphy MG, Gottesdiener KM, Hustad CM, Lates C, Kraft WK, Van Buren S, Waldman SA, Greenberg HE. Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects. Clin Ther. 2003 May; 25(5):1407-19. PMID: 12867217.
      Citations:    
    235. Musson DG, Majumdar A, Birk K, Holland S, Wickersham P, Li SX, Mistry G, Fisher A, Waldman S, Greenberg H, Deutsch P, Rogers JD. Pharmacokinetics of intramuscularly administered ertapenem. Antimicrob Agents Chemother. 2003 May; 47(5):1732-5. PMID: 12709348.
      Citations:    
    236. Casale TB, Blaiss MS, Gelfand E, Gilmore T, Harvey PD, Hindmarch I, Simons FE, Spangler DL, Szefler SJ, Terndrup TE, Waldman SA, Weiler J, Wong DF. First do no harm: managing antihistamine impairment in patients with allergic rhinitis. J Allergy Clin Immunol. 2003 May; 111(5):S835-42. PMID: 12743547.
      Citations:    
    237. Pitari GM, Zingman LV, Hodgson DM, Alekseev AE, Kazerounian S, Bienengraeber M, Hajn?czky G, Terzic A, Waldman SA. Bacterial enterotoxins are associated with resistance to colon cancer. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2695-9. PMID: 12594332.
      Citations:    
    238. Rathi S, Kazerounian S, Banwait K, Schulz S, Waldman SA, Rattan S. Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter. J Pharmacol Exp Ther. 2003 May; 305(2):615-24. PMID: 12606629.
      Citations:    
    239. Majumdar AK, Musson DG, Birk KL, Kitchen CJ, Holland S, McCrea J, Mistry G, Hesney M, Xi L, Li SX, Haesen R, Blum RA, Lins RL, Greenberg H, Waldman S, Deutsch P, Rogers JD. Pharmacokinetics of ertapenem in healthy young volunteers. Antimicrob Agents Chemother. 2002 Nov; 46(11):3506-11. PMID: 12384357.
      Citations:    
    240. Park J, Schulz S, Haaf J, Kairys JC, Waldman SA. Ectopic expression of guanylyl cyclase C in adenocarcinomas of the esophagus and stomach. Cancer Epidemiol Biomarkers Prev. 2002 Aug; 11(8):739-44. PMID: 12163327.
      Citations:    
    241. Waldman SA. Does potency predict clinical efficacy? Illustration through an antihistamine model. Ann Allergy Asthma Immunol. 2002 Jul; 89(1):7-11; quiz 11-2, 77. PMID: 12141724.
      Citations:    
    242. Wolfe HR, Waldman SA. A comparative molecular field analysis (COMFA) of the structural determinants of heat-stable enterotoxins mediating activation of guanylyl cyclase C. J Med Chem. 2002 Apr 11; 45(8):1731-4. PMID: 11931628.
      Citations:    
    243. Ruiz-Stewart I, Kazerounian S, Pitari GM, Schulz S, Waldman SA. Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides. Eur J Biochem. 2002 Apr; 269(8):2186-93. PMID: 11985597.
      Citations:    
    244. Kazerounian S, Pitari GM, Ruiz-Stewart I, Schulz S, Waldman SA. Nitric oxide activation of soluble guanylyl cyclase reveals high and low affinity sites that mediate allosteric inhibition by calcium. Biochemistry. 2002 Mar 12; 41(10):3396-404. PMID: 11876648.
      Citations:    
    245. Wolfe HR, Mendizabal M, Lleong E, Cuthbertson A, Desai V, Pullan S, Fujii DK, Morrison M, Pither R, Waldman SA. In vivo imaging of human colon cancer xenografts in immunodeficient mice using a guanylyl cyclase C--specific ligand. J Nucl Med. 2002 Mar; 43(3):392-9. PMID: 11884500.
      Citations:    
    246. Stone JA, Holland SD, Wickersham PJ, Sterrett A, Schwartz M, Bonfiglio C, Hesney M, Winchell GA, Deutsch PJ, Greenberg H, Hunt TL, Waldman SA. Single- and multiple-dose pharmacokinetics of caspofungin in healthy men. Antimicrob Agents Chemother. 2002 Mar; 46(3):739-45. PMID: 11850256.
      Citations:    
    247. Di Guglielmo MD, Park J, Schulz S, Waldman SA. Nucleotide requirements for CDX2 binding to the cis promoter element mediating intestine-specific expression of guanylyl cyclase C. FEBS Lett. 2001 Oct 26; 507(2):128-32. PMID: 11684084.
      Citations:    
    248. Fava TA, Desnoyers R, Schulz S, Park J, Weinberg D, Mitchell E, Waldman SA. Ectopic expression of guanylyl cyclase C in CD34+ progenitor cells in peripheral blood. J Clin Oncol. 2001 Oct 01; 19(19):3951-9. PMID: 11579116.
      Citations:    
    249. Pitari GM, Di Guglielmo MD, Park J, Schulz S, Waldman SA. Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells. Proc Natl Acad Sci U S A. 2001 Jul 03; 98(14):7846-51. PMID: 11438734.
      Citations:    
    250. Kraft WK, Waldman SA. Manufacturer's drug interaction and postmarketing adverse event data: what are appropriate uses? Drug Saf. 2001; 24(9):637-43. PMID: 11522118.
      Citations:    
    251. Greenberg HE, Gottesdiener K, Huntington M, Wong P, Larson P, Wildonger L, Gillen L, Dorval E, Waldman SA. A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. J Clin Pharmacol. 2000 Dec; 40(12 Pt 2):1509-15. PMID: 11185674.
      Citations:    
    252. Prueksaritanont T, Vega JM, Rogers JD, Gagliano K, Greenberg HE, Gillen L, Brucker MJ, McLoughlin D, Wong PH, Waldman SA. Simvastatin does not affect CYP3A activity, quantified by the erythromycin breath test and oral midazolam pharmacokinetics, in healthy male subjects. J Clin Pharmacol. 2000 Nov; 40(11):1274-9. PMID: 11075313.
      Citations:    
    253. Lucas KA, Pitari GM, Kazerounian S, Ruiz-Stewart I, Park J, Schulz S, Chepenik KP, Waldman SA. Guanylyl cyclases and signaling by cyclic GMP. Pharmacol Rev. 2000 Sep; 52(3):375-414. PMID: 10977868.
      Citations:    
    254. Zannikos PN, Jensen BK, Boutouyrie BX, Tripp L, Yongyi L, McGowan T, Waldman SA, Greenberg HE. Pharmacokinetics and safety of single intravenous infusions of the adenosine agonist, AMP 579, in patients with end-stage renal insufficiency. J Clin Pharmacol. 2000 Jul; 40(7):745-51. PMID: 10883416.
      Citations:    
    255. Weinberg DS, Desnoyers R, Gelmann A, Boman BM, Waldman SA. Postoperative management of local colorectal cancer: therapy and surveillance. Semin Gastrointest Dis. 2000 Jul; 11(3):152-6. PMID: 10950462.
      Citations:    
    256. Park J, Schulz S, Waldman SA. Intestine-specific activity of the human guanylyl cyclase C promoter is regulated by Cdx2. Gastroenterology. 2000 Jul; 119(1):89-96. PMID: 10889158.
      Citations:    
    257. Gelmann A, Desnoyers R, Cagir B, Weinberg D, Boman BM, Waldman SA. Colorectal cancer staging and adjuvant chemotherapy. Expert Opin Pharmacother. 2000 May; 1(4):737-55. PMID: 11249513.
      Citations:    
    258. Weinberg DS, So C, Ruggeri B, Biswas S, Barber M, Waldman S. Human cholecystokinin-A receptor is not an oncofetal protein. Dig Dis Sci. 2000 Mar; 45(3):538-43. PMID: 10749330.
      Citations:    
    259. Pearlman JM, Prawer SP, Barber MT, Parkinson SJ, Schulz S, Park J, Zook M, Waldman SA. A splice variant of the transcript for guanylyl cyclase C is expressed in human colon and colorectal cancer cells. Dig Dis Sci. 2000 Feb; 45(2):298-305. PMID: 10711442.
      Citations:    
    260. Cagir B, Gelmann A, Park J, Fava T, Tankelevitch A, Bittner EW, Weaver EJ, Palazzo JP, Weinberg D, Fry RD, Waldman SA. Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer. Ann Intern Med. 1999 Dec 07; 131(11):805-12. PMID: 10610624.
      Citations:    
    261. McCrea J, Prueksaritanont T, Gertz BJ, Carides A, Gillen L, Antonello S, Brucker MJ, Miller-Stein C, Osborne B, Waldman S. Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity. J Clin Pharmacol. 1999 Dec; 39(12):1212-20. PMID: 10586386.
      Citations:    
    262. Waldman SA, Terzic A. The Molecular Therapeutics Section of the American Society for Clinical Pharmacology and Therapeutics. Clin Pharmacol Ther. 1999 Oct; 66(4):336-7. PMID: 10546916.
      Citations:    
    263. Parkinson SJ, Jovanovic A, Jovanovic S, Wagner F, Terzic A, Waldman SA. Regulation of nitric oxide-responsive recombinant soluble guanylyl cyclase by calcium. Biochemistry. 1999 May 18; 38(20):6441-8. PMID: 10350462.
      Citations:    
    264. Zhang W, Mannan I, Schulz S, Parkinson SJ, Alekseev AE, Gomez LA, Terzic A, Waldman SA. Interruption of transmembrane signaling as a novel antisecretory strategy to treat enterotoxigenic diarrhea. FASEB J. 1999 May; 13(8):913-22. PMID: 10224234.
      Citations:    
    265. McCrea JB, Cribb A, Rushmore T, Osborne B, Gillen L, Lo MW, Waldman S, Bjornsson T, Spielberg S, Goldberg MR. Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174. Clin Pharmacol Ther. 1999 Mar; 65(3):348-52. PMID: 10096267.
      Citations:    
    266. Schulz S, Waldman SA. The guanylyl cyclase family of natriuretic peptide receptors. Vitam Horm. 1999; 57:123-51. PMID: 10232048.
      Citations:    
    267. Thiyagarajan MM, Waldman SA, No? M, Kmiec EB. Binding characteristics of Ustilago maydis topoisomerase I to DNA containing secondary structures. Eur J Biochem. 1998 Jul 15; 255(2):347-55. PMID: 9716375.
      Citations:    
    268. Waldman SA, Barber M, Pearlman J, Park J, George R, Parkinson SJ. Heterogeneity of guanylyl cyclase C expressed by human colorectal cancer cell lines in vitro. Cancer Epidemiol Biomarkers Prev. 1998 Jun; 7(6):505-14. PMID: 9641495.
      Citations:    
    269. Gharaibeh MN, Gillen LP, Osborne B, Schwartz JI, Waldman SA. Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers. J Clin Pharmacol. 1998 Jun; 38(6):492-5. PMID: 9650537.
      Citations:    
    270. Waldman SA, Cagir B, Rakinic J, Fry RD, Goldstein SD, Isenberg G, Barber M, Biswas S, Minimo C, Palazzo J, Park PK, Weinberg D. Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer. Dis Colon Rectum. 1998 Mar; 41(3):310-5. PMID: 9514425.
      Citations:    
    271. Kraft W, Greenberg HE, Waldman SA. Paradoxical hypotension and bradycardia after intravenous arginine vasopressin. J Clin Pharmacol. 1998 Mar; 38(3):283-6. PMID: 9549667.
      Citations:    
    272. Yeh KC, Deutsch PJ, Haddix H, Hesney M, Hoagland V, Ju WD, Justice SJ, Osborne B, Sterrett AT, Stone JA, Woolf E, Waldman S. Single-dose pharmacokinetics of indinavir and the effect of food. Antimicrob Agents Chemother. 1998 Feb; 42(2):332-8. PMID: 9527781.
      Citations:    
    273. Deshmane SP, Parkinson SJ, Crupper SS, Robertson DC, Schulz S, Waldman SA. Cytoplasmic domains mediate the ligand-induced affinity shift of guanylyl cyclase C. Biochemistry. 1997 Oct 21; 36(42):12921-9. PMID: 9335551.
      Citations:    
    274. Weinberg DS, Ruggeri B, Barber MT, Biswas S, Miknyocki S, Waldman SA. Cholecystokinin A and B receptors are differentially expressed in normal pancreas and pancreatic adenocarcinoma. J Clin Invest. 1997 Aug 01; 100(3):597-603. PMID: 9239407.
      Citations:    
    275. Parkinson SJ, Alekseev AE, Gomez LA, Wagner F, Terzic A, Waldman SA. Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine. J Biol Chem. 1997 Jan 10; 272(2):754-8. PMID: 8995360.
      Citations:    
    276. Carrithers SL, Barber MT, Biswas S, Parkinson SJ, Park PK, Goldstein SD, Waldman SA. Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues. Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25):14827-32. PMID: 8962140.
      Citations:    
    277. Waldman SA, Vitow C, Osborne B, Gillen L, Argentieri DC, Wong FA, Smith IL, Chow AT, Misiti J, Bjornsson TD. Pharmacokinetics and pharmacodynamics of tepoxalin after single oral dose administration to healthy volunteers. J Clin Pharmacol. 1996 May; 36(5):462-8. PMID: 8739025.
      Citations:    
    278. Ryan SV, Carrithers SL, Parkinson SJ, Skurk C, Nuss C, Pooler PM, Owen CS, Lefer AM, Waldman SA. Hypotensive mechanisms of amifostine. J Clin Pharmacol. 1996 Apr; 36(4):365-73. PMID: 8728352.
      Citations:    
    279. Parkinson SJ, Waldman SA. An intracellular adenine nucleotide binding site inhibits guanyly cyclase C by a guanine nucleotide-dependent mechanism. Biochemistry. 1996 Mar 12; 35(10):3213-21. PMID: 8605156.
      Citations:    
    280. Carrithers SL, Parkinson SJ, Goldstein SD, Park PK, Urbanski RW, Waldman SA. Escherichia coli heat-stable enterotoxin receptors. A novel marker for colorectal tumors. Dis Colon Rectum. 1996 Feb; 39(2):171-81. PMID: 8620784.
      Citations:    
    281. Murohara T, Parkinson SJ, Waldman SA, Lefer AM. Inhibition of nitric oxide biosynthesis promotes P-selectin expression in platelets. Role of protein kinase C. Arterioscler Thromb Vasc Biol. 1995 Nov; 15(11):2068-75. PMID: 7583591.
      Citations:    
    282. Kong AN, Tomasko L, Waldman SA, Osborne B, Deutsch PJ, Goldberg MR, Bjornsson TD. Losartan does not affect the pharmacokinetics and pharmacodynamics of warfarin. J Clin Pharmacol. 1995 Oct; 35(10):1008-15. PMID: 8568008.
      Citations:    
    283. Urbanski R, Carrithers SL, Waldman SA. Internalization of E. coli ST mediated by guanylyl cyclase C in T84 human colon carcinoma cells. Biochim Biophys Acta. 1995 Aug 17; 1245(1):29-36. PMID: 7654763.
      Citations:    
    284. Deshmane SP, Carrithers SL, Parkinson SJ, Crupper SS, Robertson DC, Waldman SA. Rat guanylyl cyclase C expressed in COS-7 cells exhibits multiple affinities for Escherichia coli heat-stable enterotoxin. Biochemistry. 1995 Jul 18; 34(28):9095-102. PMID: 7619807.
      Citations:    
    285. Patrinellis AC, Waldman SA. Allosteric regulation by calcium of rabbit polyclonal anti-cyclic GMP antibody. Biochim Biophys Acta. 1995 Feb 23; 1243(2):143-50. PMID: 7873556.
      Citations:    
    286. Waldman SA, Morganroth J. Effects of food on the bioequivalence of different verapamil sustained-release formulations. J Clin Pharmacol. 1995 Feb; 35(2):163-9. PMID: 7751427.
      Citations:    
    287. Goldberg MR, Bradstreet TE, McWilliams EJ, Tanaka WK, Lipert S, Bjornsson TD, Waldman SA, Osborne B, Pivadori L, Lewis G, et al. Biochemical effects of losartan, a nonpeptide angiotensin II receptor antagonist, on the renin-angiotensin-aldosterone system in hypertensive patients. Hypertension. 1995 Jan; 25(1):37-46. PMID: 7843751.
      Citations:    
    288. Carrithers SL, Parkinson SJ, Goldstein S, Park P, Robertson DC, Waldman SA. Escherichia coli heat-stable toxin receptors in human colonic tumors. Gastroenterology. 1994 Dec; 107(6):1653-61. PMID: 7958675.
      Citations:    
    289. Waldman SA, Phillips K, Parkinson SJ. Intestinal kinetics and dynamics of Escherichia coli heat-stabile enterotoxin in suckling mice. J Infect Dis. 1994 Dec; 170(6):1498-507. PMID: 7995990.
      Citations:    
    290. Parkinson SJ, Carrithers SL, Waldman SA. Opposing adenine nucleotide-dependent pathways regulate guanylyl cyclase C in rat intestine. J Biol Chem. 1994 Sep 09; 269(36):22683-90. PMID: 7915717.
      Citations:    
    291. Leitman DC, Waldman SA, Murad F. Regulation of particulate guanylate cyclase by natriuretic peptides and Escherichia coli heat-stable enterotoxin. Adv Pharmacol. 1994; 26:67-86. PMID: 7913619.
      Citations:    
    292. Hakki S, Robertson DC, Waldman SA. A 56 kDa binding protein for Escherichia coli heat-stable enterotoxin isolated from the cytoskeleton of rat intestinal membrane does not possess guanylate cyclase activity. Biochim Biophys Acta. 1993 Oct 10; 1152(1):1-8. PMID: 8104484.
      Citations:    
    293. Morganroth J, Waldman SA. Sensitivity in detecting drug-induced alterations in the PR interval: comparison of the surface electrocardiogram measured by a cardiologist versus routine automated computer analysis. Am J Cardiol. 1993 Oct 01; 72(11):834-6. PMID: 8213522.
      Citations:    
    294. Hakki S, Crane M, Hugues M, O'Hanley P, Waldman SA. Solubilization and characterization of functionally coupled Escherichia coli heat-stable toxin receptors and particulate guanylate cyclase associated with the cytoskeleton compartment of intestinal membranes. Int J Biochem. 1993 Apr; 25(4):557-66. PMID: 8096825.
      Citations:    
    295. Crane MR, Hugues M, O'Hanley PD, Waldman SA. Identification of two affinity states of low affinity receptors for Escherichia coli heat-stable enterotoxin: correlation of occupation of lower affinity state with guanylate cyclase activation. Mol Pharmacol. 1992 Jun; 41(6):1073-80. PMID: 1352035.
      Citations:    
    296. Hugues M, Crane MR, Thomas BR, Robertson D, Gazzano H, O'Hanley P, Waldman SA. Affinity purification of functional receptors for Escherichia coli heat-stable enterotoxin from rat intestine. Biochemistry. 1992 Jan 14; 31(1):12-6. PMID: 1310026.
      Citations:    
    297. Ardalan B, Stridhar K, Reddy R, Benedetto P, Richman S, Waldman S, Morrell L, Feun L, Savaraj N, Livingstone A. Phase I study of high dose 5-fluorouracil and high dose Leucovorin with low dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies. Int J Radiat Oncol Biol Phys. 1992; 22(3):511-4. PMID: 1735689.
      Citations:    
    298. Hugues M, Crane M, Hakki S, O'Hanley P, Waldman SA. Identification and characterization of a new family of high-affinity receptors for Escherichia coli heat-stable enterotoxin in rat intestinal membranes. Biochemistry. 1991 Nov 05; 30(44):10738-45. PMID: 1681902.
      Citations:    
    299. Ardalan B, Sridhar KS, Benedetto P, Richman S, Waldman S, Morrell L, Feun L, Savaraj N, Fodor M, Livingstone A. A phase I, II study of high-dose 5-fluorouracil and high-dose leucovorin with low-dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies. Cancer. 1991 Sep 15; 68(6):1242-6. PMID: 1873776.
      Citations:    
    300. Gazzano H, Wu HI, Waldman SA. Activation of particulate guanylate cyclase by Escherichia coli heat-stable enterotoxin is regulated by adenine nucleotides. Infect Immun. 1991 Apr; 59(4):1552-7. PMID: 1672303.
      Citations:    
    301. Ardalan B, Chua L, Tian EM, Reddy R, Sridhar K, Benedetto P, Richman S, Legaspi A, Waldman S, Morrell L, et al. A phase II study of weekly 24-hour infusion with high-dose fluorouracil with leucovorin in colorectal carcinoma. J Clin Oncol. 1991 Apr; 9(4):625-30. PMID: 2066758.
      Citations:    
    302. Gazzano H, Wu HI, Waldman SA. Adenine nucleotide regulation of particulate guanylate cyclase from rat lung. Biochim Biophys Acta. 1991 Mar 08; 1077(1):99-106. PMID: 1672612.
      Citations:    
    303. Waldman SA, Leitman DC, Murad F. Immunoaffinity purification of soluble guanylyl cyclase. Methods Enzymol. 1991; 195:391-6. PMID: 1674571.
      Citations:    
    304. Waldman SA, Leitman DC, Murad F. Copurification of atrial natriuretic peptide receptor and particulate guanylyl cyclase. Methods Enzymol. 1991; 195:397-404. PMID: 1674572.
      Citations:    
    305. Leitman DC, Waldman SA, Murad F. Identification of atrial natriuretic peptide receptors in cultured cells. Methods Enzymol. 1991; 195:436-46. PMID: 1674576.
      Citations:    
    306. Hussein AM, Feun LG, Sridhar KS, Benedetto P, Waldman S, Otrakji CL. Combination chemotherapy and radiotherapy for small-cell carcinoma of the esophagus. A case report of long-term survival and review of the literature. Am J Clin Oncol. 1990 Oct; 13(5):369-73. PMID: 2171315.
      Citations:    
    307. Crane MR, O'Hanley P, Waldman SA. Rat intestinal cell atrial natriuretic peptide receptor coupled to guanylate cyclase. Gastroenterology. 1990 Jul; 99(1):125-31. PMID: 1971606.
      Citations:    
    308. Ivens K, Gazzano H, O'Hanley P, Waldman SA. Heterogeneity of intestinal receptors for Escherichia coli heat-stable enterotoxin. Infect Immun. 1990 Jun; 58(6):1817-20. PMID: 2160433.
      Citations:    
    309. Waldman SA, Rapoport RM, Fiscus RR, Leitman DC, Chang LY, Murad F. Regulation of particulate guanylate cyclase by atriopeptins: relation between peptide structure, receptor binding, and enzyme kinetics. Biochim Biophys Acta. 1989 Nov 30; 999(2):157-62. PMID: 2574598.
      Citations:    
    310. Waldman SA, Leitman DC, Chang LY, Murad F. Comparison of particulate guanylate cyclase in cells with and without atrial natriuretic peptide receptor binding activity. Mol Cell Biochem. 1989 Oct 05; 90(1):19-25. PMID: 2575208.
      Citations:    
    311. Waldman SA, O'Hanley P. Influence of a glycine or proline substitution on the functional properties of a 14-amino-acid analog of Escherichia coli heat-stable enterotoxin. Infect Immun. 1989 Aug; 57(8):2420-4. PMID: 2568345.
      Citations:    
    312. Waldman SA, Murad F. Atrial natriuretic peptides: receptors and second messengers. Bioessays. 1989 Jan; 10(1):16-9. PMID: 2540738.
      Citations:    
    313. Carr S, Gazzano H, Waldman SA. Regulation of particulate guanylate cyclase by Escherichia coli heat-stable enterotoxin: receptor binding and enzyme kinetics. Int J Biochem. 1989; 21(11):1211-5. PMID: 2575546.
      Citations:    
    314. Bennett BM, Schr?der H, Hayward LD, Waldman SA, Murad F. Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation, and guanylate cyclase activation by glyceryl trinitrate and the enantiomers of isoidide dinitrate. Circ Res. 1988 Oct; 63(4):693-701. PMID: 2901920.
      Citations:    
    315. Waldman SA, Leitman DC, Andresen J, Murad F. Guanylate cyclase and the adrenal natriuretic factor receptor. Science. 1988 May 06; 240(4853):805-6. PMID: 2896389.
      Citations:    
    316. Schr?der H, Leitman DC, Bennett BM, Waldman SA, Murad F. Glyceryl trinitrate-induced desensitization of guanylate cyclase in cultured rat lung fibroblasts. J Pharmacol Exp Ther. 1988 May; 245(2):413-8. PMID: 2452870.
      Citations:    
    317. Leitman DC, Agnost VL, Catalano RM, Schr?der H, Waldman SA, Bennett BM, Tuan JJ, Murad F. Atrial natriuretic peptide, oxytocin, and vasopressin increase guanosine 3',5'-monophosphate in LLC-PK1 kidney epithelial cells. Endocrinology. 1988 Apr; 122(4):1478-85. PMID: 2894298.
      Citations:    
    318. Leitman DC, Andresen JW, Catalano RM, Waldman SA, Tuan JJ, Murad F. Atrial natriuretic peptide binding, cross-linking, and stimulation of cyclic GMP accumulation and particulate guanylate cyclase activity in cultured cells. J Biol Chem. 1988 Mar 15; 263(8):3720-8. PMID: 2894373.
      Citations:    
    319. Waldman SA, Murad F. Biochemical mechanisms underlying vascular smooth muscle relaxation: the guanylate cyclase-cyclic GMP system. J Cardiovasc Pharmacol. 1988; 12 Suppl 5:S115-8. PMID: 2469867.
      Citations:    
    320. Murad F, Leitman D, Waldman S, Chang CH, Hirata M, Kohse K. Effects of nitrovasodilators, endothelium-dependent vasodilators, and atrial peptides on cGMP. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:1005-9. PMID: 2908195.
      Citations:    
    321. Molina CR, Andresen JW, Rapoport RM, Waldman S, Murad F. Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta. J Cardiovasc Pharmacol. 1987 Oct; 10(4):371-8. PMID: 2444789.
      Citations:    
    322. Murad F, Leitman DC, Bennett BM, Molina C, Waldman SA. Regulation of guanylate cyclase by atrial natriuretic factor and the role of cyclic GMP in vasodilation. Am J Med Sci. 1987 Sep; 294(3):139-43. PMID: 2889359.
      Citations:    
    323. Waldman SA, Murad F. Cyclic GMP synthesis and function. Pharmacol Rev. 1987 Sep; 39(3):163-96. PMID: 2827195.
      Citations:    
    324. Rapoport RM, Waldman SA, Ginsburg R, Molina CR, Murad F. Effects of glyceryl trinitrate on endothelium-dependent and -independent relaxation and cyclic GMP levels in rat aorta and human coronary artery. J Cardiovasc Pharmacol. 1987 Jul; 10(1):82-9. PMID: 2441158.
      Citations:    
    325. Fiscus RR, Robles BT, Waldman SA, Murad F. Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures. J Neurochem. 1987 Feb; 48(2):522-8. PMID: 2432184.
      Citations:    
    326. Murad F, Waldman S, Molina C, Bennett B, Leitman D. Regulation and role of guanylate cyclase-cyclic GMP in vascular relaxation. Prog Clin Biol Res. 1987; 249:65-76. PMID: 2890172.
      Citations:    
    327. Kamisaki Y, Waldman SA, Murad F. The involvement of catalytic site thiol groups in the activation of soluble guanylate cyclase by sodium nitroprusside. Arch Biochem Biophys. 1986 Dec; 251(2):709-14. PMID: 2879512.
      Citations:    
    328. Waldman SA, Rapoport RM, Ginsburg R, Murad F. Desensitization to nitroglycerin in vascular smooth muscle from rat and human. Biochem Pharmacol. 1986 Oct 15; 35(20):3525-31. PMID: 2876710.
      Citations:    
    329. Kamisaki Y, Saheki S, Nakane M, Palmieri JA, Kuno T, Chang BY, Waldman SA, Murad F. Soluble guanylate cyclase from rat lung exists as a heterodimer. J Biol Chem. 1986 Jun 05; 261(16):7236-41. PMID: 2872214.
      Citations:    
    330. Rapoport RM, Ginsburg R, Waldman SA, Murad F. Effects of atriopeptins on relaxation and cyclic GMP levels in human coronary artery in vitro. Eur J Pharmacol. 1986 May 13; 124(1-2):193-6. PMID: 3013659.
      Citations:    
    331. Kuno T, Andresen JW, Kamisaki Y, Waldman SA, Chang LY, Saheki S, Leitman DC, Nakane M, Murad F. Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung. J Biol Chem. 1986 May 05; 261(13):5817-23. PMID: 2871018.
      Citations:    
    332. Kuno T, Kamisaki Y, Waldman SA, Gariepy J, Schoolnik G, Murad F. Characterization of the receptor for heat-stable enterotoxin from Escherichia coli in rat intestine. J Biol Chem. 1986 Jan 25; 261(3):1470-6. PMID: 3944095.
      Citations:    
    333. Rapoport RM, Winquist RJ, Baskin EP, Faison EP, Waldman SA, Murad F. Effects of atriopeptins on relaxation and cyclic GMP levels in rat and rabbit aortas. Eur J Pharmacol. 1986 Jan 14; 120(1):123-6. PMID: 3004998.
      Citations:    
    334. Murad F, Waldman SA, Fiscus RR, Rapoport RM. Regulation of cyclic GMP synthesis and the interactions with calcium. J Cardiovasc Pharmacol. 1986; 8 Suppl 8:S57-60. PMID: 2433527.
      Citations:    
    335. Waldman SA, Kuno T, Kamisaki Y, Chang LY, Gariepy J, O'Hanley P, Schoolnik G, Murad F. Intestinal receptor for heat-stable enterotoxin of Escherichia coli is tightly coupled to a novel form of particulate guanylate cyclase. Infect Immun. 1986 Jan; 51(1):320-6. PMID: 2867046.
      Citations:    
    336. Rapoport RM, Waldman SA, Schwartz K, Winquist RJ, Murad F. Effects of atrial natriuretic factor, sodium nitroprusside, and acetylcholine on cyclic GMP levels and relaxation in rat aorta. Eur J Pharmacol. 1985 Sep 24; 115(2-3):219-29. PMID: 2998822.
      Citations:    
    337. Fiscus RR, Rapoport RM, Waldman SA, Murad F. Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta. Biochim Biophys Acta. 1985 Jul 30; 846(1):179-84. PMID: 2990577.
      Citations:    
    338. Waldman SA, Rapoport RM, Fiscus RR, Murad F. Effects of atriopeptin on particulate guanylate cyclase from rat adrenal. Biochim Biophys Acta. 1985 May 30; 845(2):298-303. PMID: 2859896.
      Citations:    
    339. Leitman DC, Waldman SA, Rapoport RM, Murad F. Specific atrial natriuretic factor receptors mediate increased cyclic GMP accumulation in cultured bovine aortic endothelial and smooth muscle cells. Trans Assoc Am Physicians. 1985; 98:243-52. PMID: 3022442.
      Citations:    
    340. Waldman SA, Chang LY, Murad F. A two-step procedure for obtaining highly purified particulate guanylate cyclase from rat lung. Prep Biochem. 1985; 15(3):103-19. PMID: 2865723.
      Citations:    
    341. Waldman SA, Rapoport RM, Murad F. Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues. J Biol Chem. 1984 Dec 10; 259(23):14332-4. PMID: 6150043.
      Citations:    
    342. Winquist RJ, Faison EP, Waldman SA, Schwartz K, Murad F, Rapoport RM. Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7661-4. PMID: 6150486.
      Citations:    
    343. Gariepy J, O'Hanley P, Waldman SA, Murad F, Schoolnik GK. A common antigenic determinant found in two functionally unrelated toxins. J Exp Med. 1984 Oct 01; 160(4):1253-8. PMID: 6207263.
      Citations:    
    344. Waldman SA, Sinacore MS, Lewicki JA, Chang LY, Murad F. Selective activation of particulate guanylate cyclase by a specific class of porphyrins. J Biol Chem. 1984 Apr 10; 259(7):4038-42. PMID: 6142894.
      Citations:    
    345. Waldman SA, O'Hanley P, Falkow S, Schoolnik G, Murad F. A simple, sensitive, and specific assay for the heat-stable enterotoxin of Escherichia coli. J Infect Dis. 1984 Jan; 149(1):83-9. PMID: 6141207.
      Citations:    
    346. Waldman SA, Chepenik KP, Waite BM. Acyl composition and phospholipase activities in plasma membranes isolated from rat embryos. Int J Biochem. 1984; 16(6):593-9. PMID: 6468725.
      Citations:    
    347. Waldman SA, Lewicki JA, Chang LY, Murad F. Highly purified particulate guanylate cyclase from rat lung: characterization and comparison with soluble guanylate cyclase. Mol Cell Biochem. 1983; 57(2):155-66. PMID: 6140625.
      Citations:    
    348. Brandwein HJ, Lewicki JA, Waldman SA, Murad F. Effect of GTP analogues on purified soluble guanylate cyclase. J Biol Chem. 1982 Feb 10; 257(3):1309-11. PMID: 6120166.
      Citations:    
    349. Waldman SA, Lewicki JA, Brandwein HJ, Murad F. Partial purification and characterization of particulate guanylate cyclase from rat liver after solubilization with trypsin. J Cyclic Nucleotide Res. 1982; 8(6):359-70. PMID: 6136535.
      Citations:    
    350. Murad F, Lewicki JA, Brandwein HJ, Mittal CK, Waldman SA. Guanylate cyclase: purification, properties, free radical activation, radiolabeling, and preparation of hybridoma antibodies. Adv Cyclic Nucleotide Res. 1981; 14:229-39. PMID: 6116385.
      Citations:    
    351. Waldman SA, Chepenik KP. Characterization and comparison of two plasma membrane reference enzymes with those of other organelles during mammalian embryogenesis. Int J Biochem. 1980; 11(2):155-60. PMID: 6244203.
      Citations:    
    352. Lewicki JA, Brandwein HJ, Waldman SA, Murad F. Purified guanylate cyclase: characterization, iodination and preparation of monoclonal antibodies. J Cyclic Nucleotide Res. 1980; 6(4):283-96. PMID: 6110682.
      Citations:    
    353. PELNER L, WALDMAN S. On the possibility of hepatic "hyperfunction" (hyperhepatism) in hypersensitivity reactions. Gastroenterology. 1952 Apr; 20(4):669-71. PMID: 14917190.
      Citations:    
    354. WALDMAN S, PELNER L. The action of neostigmine in supraventricular tachycardias. Ann Intern Med. 1948 Jul; 29(1):53-63. PMID: 18869860.
      Citations:    
    355. WALDMAN S, PELNER L. Burning sensation of the tongue, (glossodynia); an analysis of cases that are not due to vitamin B deficiency. Gastroenterology. 1948 Jun; 10(6):965-9. PMID: 18867640.
      Citations:    
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