Thomas Jefferson University

Steven McKenzie

TitleProfessor
InstitutionThomas Jefferson University
DepartmentHematology
Address1020 Locust St.
Philadelphia PA 19107
Phone215-955-8544
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    Collapse Overview 
    Collapse overview

    REVIEW BOARD MEMBERSHIP
    1996 - present
    Review Committee Member, National Institutes of Health, National Cancer Institute
    Chair, Innovative Technologies for the Molecular Analysis of Cancer study section
    Member of reviewer reserve, Innovative Technologies
    Ad hoc, National Heart Lung and Blood Institute


    Collapse Research 
    Collapse research activities and funding
    R01HL061865     (MCKENZIE, STEVEN E.)Sep 30, 1998 - Aug 31, 2003
    NIH
    MODELS OF THROMBOCYTOPENIA PATHOLOGY &TREATMENT
    Role: Principal Investigator
    C06RR028626     (MCKENZIE, STEVEN E.)Jan 26, 2010 - Feb 28, 2013
    NIH
    Jefferson Alumni Hall 3 West Lab Modernization
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Aid M, Stephenson KE, Collier AY, Nkolola JP, Michael JV, McKenzie SE, Barouch DH. Activation of coagulation and proinflammatory pathways in thrombosis with thrombocytopenia syndrome and following COVID-19 vaccination. Nat Commun. 2023 Oct 23; 14(1):6703. PMID: 37872311.
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    2. Denorme F, Armstrong ND, Stoller ML, Portier I, Tugolukova EA, Tanner RM, Montenont E, Bhatlekar S, Cody M, Rustad JL, Ajanel A, Tolley ND, Murray DC, Boyle JL, Nieman MT, McKenzie SE, Yost CC, Lange LA, Cushman M, Irvin MR, Bray PF, Campbell RA. The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes. J Clin Invest. 2023 Jul 20. PMID: 37471144.
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    3. Renna SA, Zhao X, Kunapuli SP, Ma P, Holinstat M, Boxer MB, Maloney DJ, Michael JV, McKenzie SE. Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition. Arterioscler Thromb Vasc Biol. 2023 Jun 22. PMID: 37345522.
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    4. Renna SA, McKenzie SE, Michael JV. Species Differences in Platelet Protease-Activated Receptors. Int J Mol Sci. 2023 May 05; 24(9). PMID: 37176005.
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    5. Rhoades R, French Z, Yang A, Walsh K, Drelich DA, McKenzie SE. Perioperative Outcomes of Patients with Bleeding Disorders Undergoing Major Surgery at an Academic Hemophilia Treatment Center. Clin Appl Thromb Hemost. 2023 Jan-Dec; 29:10760296231165056. PMID: 36972481.
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    6. McKenzie SE. A vision for a quicker definitive diagnosis of HIT. Blood. 2022 12 22; 140(25):2657-2658. PMID: 36548019.
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    7. Boelig RC, Cahanap TJ, Ma L, Zhan T, Berghella V, Chan JSY, Kraft WK, Mckenzie SE. Platelet protease activated receptor 4 (PAR 4) Receptor Genotype is Associated with an Increased Risk of Preterm Birth. J Thromb Haemost. 2022 Jul 11. PMID: 35815338.
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    8. Zhao X, Cooper M, Michael JV, Yarman Y, Baltz A, Chuprun JK, Koch WJ, McKenzie SE, Tomaiuolo M, Stalker TJ, Zhu L, Ma P. GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12. Blood Adv. 2022 06 17. PMID: 35793439.
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    9. Huynh A, Arnold DM, Michael JV, Clare R, Smith JW, Daka M, Ianosi-Irimie M, McKenzie SE, Kelton JG, Nazy I. Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S. Blood Adv. 2022 Apr 04. PMID: 35377937.
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    10. Renna SA, Michael JV, Kong X, Ma L, Ma P, Nieman MT, Edelstein LC, McKenzie SE. Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice. J Thromb Haemost. 2022 Feb 13. PMID: 35152546.
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    11. McKenzie SE. Sugar and spike: not so nice. Blood. 2021 Oct 21; 138(16):1386-1387. PMID: 34673948.
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    12. Downes K, Zhao X, Gleadall NS, McKinney H, Kempster C, Batista J, Thomas P, Cooper M, Michael JV, Kreuzhuber R, Wedderburn K, Waller K, Varney B, Verdier H, Kriek N, Ashford SE, Stirrups KE, Dunster JL, McKenzie SE, Ouwehand WH, Gibbins JM, Yang J, Astle WJ, Ma P. G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. Blood Adv. 2021 Sep 28. PMID: 34581777.
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    13. Leung H, Perdomo J, Ahmadi Z, Yan F, McKenzie SE, Chong BH. Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia. Blood Adv. 2021 Sep 03. PMID: 34478504.
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    14. Choi PY, Grace RF, Therese Ahlen M, Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Althaus K, Sharma R, Bakchoul T. The SSC platelet immunology register of VITT and VIITP: Toward standardization of laboratory and clinical parameters. J Thromb Haemost. 2021 08; 19(8):2094-2095. PMID: 34076338.
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    15. Nazy I, Sachs UJ, Arnold DM, McKenzie SE, Choi P, Althaus K, Ahlen MT, Sharma R, Grace RF, Bakchoul T. Recommendations for the clinical and laboratory diagnosis of VITT against COVID-19: Communication from the ISTH SSC Subcommittee on Platelet Immunology. J Thromb Haemost. 2021 06; 19(6):1585-1588. PMID: 34018298.
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    16. Rhoades R, Leong R, Kopenitz J, Thoma B, McDermott L, Dovidio J, Barletti S, Gong JZ, Massey HT, McKenzie SE, Rame JE, Al-Rawas N. Coagulopathy monitoring and anticoagulation management in COVID-19 patients on ECMO: Advantages of a heparin anti-Xa-based titration strategy. Thromb Res. 2021 Apr 19; 203:1-4. PMID: 33894473.
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    17. Patel P, Michael JV, Naik UP, McKenzie SE. Platelet Fc?RIIA in immunity and thrombosis: Adaptive immunothrombosis. J Thromb Haemost. 2021 May; 19(5):1149-1160. PMID: 33587783.
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    18. Abraham S, Ma L, Kong X, Askari S, Edelstein LC, McKenzie SE. PCTP contributes to human platelet activation by enhancing dense granule secretion. Thromb Res. 2021 Mar 08; 202:67-73. PMID: 33770537.
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    19. Melki I, Allaeys I, Tessandier N, Lévesque T, Cloutier N, Laroche A, Vernoux N, Becker Y, Benk-Fortin H, Zufferey A, Rollet-Labelle E, Pouliot M, Poirier G, Patey N, Belleannee C, Soulet D, McKenzie SE, Brisson A, Tremblay ME, Lood C, Fortin PR, Boilard E. Platelets release mitochondrial antigens in systemic lupus erythematosus. Sci Transl Med. 2021 Feb 17; 13(581). PMID: 33597264.
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    20. Dykes KC, Johnson CA, Gong JZ, McKenzie SE, Husseinzadeh HD. Bleeding and Thrombotic Adverse Events in Hospitalized Patients Under Empiric Treatment for Suspected Heparin-Induced Thrombocytopenia While Awaiting Confirmatory Testing. Clin Appl Thromb Hemost. 2021 Jan-Dec; 27:1076029621996473. PMID: 33848189.
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    21. Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell RA, Rowley JW, Salem D, Zufferey A, Laroche A, Lévesque T, Patey N, Rauch J, Lood C, Droit A, McKenzie SE, Machlus KR, Rondina MT, Lacroix S, Fortin PR, Boilard E. Fc?RIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus. Blood. 2020 Dec 17; 136(25):2933-2945. PMID: 33331924.
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    22. Patel P, Shaik NF, Zhou Y, Golla K, McKenzie SE, Naik UP. ASK1 Regulates Immune-Mediated Thrombocytopenia, Thrombosis, and Systemic Shock. J Thromb Haemost. 2020 Aug 07. PMID: 32767736.
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    23. Tessandier N, Melki I, Cloutier N, Allaeys I, Miszta A, Tan S, Milasan A, Michel S, Benmoussa A, Lévesque T, Côté F, McKenzie SE, Gilbert C, Provost P, Brisson AR, Wolberg AS, Fortin PR, Martel C, Boilard É. Platelets Disseminate Extracellular Vesicles in Lymph in Rheumatoid Arthritis. Arterioscler Thromb Vasc Biol. 2020 Apr; 40(4):929-942. PMID: 32102567.
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    24. Chen X, Gupta S, Cooper M, DeHelian D, Zhao X, Naik MU, Wurtzel JGT, Stalker TJ, Goldfinger LE, Benovic J, Brass LF, McKenzie SE, Naik UP, Ma P. GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets. Blood Adv. 2020 Jan 14; 4(1):76-86. PMID: 31899801.
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    25. Rizk S, Axelrod D, Riddick-Burden G, Congdon-Martin E, McKenzie S, Haines C, Ward L, McAna J, Crawford AG. Clinical Transformation in Care for Patients With Sickle Cell Disease at an Urban Academic Medical Center. Am J Med Qual. 2019 Sep 09; 1062860619873402. PMID: 31496258.
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    26. Kizlik-Masson C, Deveuve Q, Zhou Y, Vayne C, Thibault G, McKenzie SE, Pouplard C, Loyau S, Gruel Y, Rollin J. Cleavage of anti-PF4/Heparin IgG by a bacterial protease and potential benefit in heparin-induced thrombocytopenia. Blood. 2019 Mar 27. PMID: 30917957.
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    27. Kostyak JC, Mauri BR, Dangelmaier C, Patel A, Zhou Y, Eble JA, Tsygankov AY, McKenzie SE, Kunapuli SP. TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists. TH Open. 2018 Oct; 2(4):e411-e419. PMID: 31249969.
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    28. Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E. Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration. Proc Natl Acad Sci U S A. 2018 Feb 13; 115(7):E1550-E1559. PMID: 29386381.
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    29. Reppschläger K, Gosselin J, Dangelmaier CA, Thomas DH, Carpino N, McKenzie SE, Kunapuli SP, Tsygankov AY. TULA-2 protein phosphatase suppresses activation of Syk through the GPVI platelet receptor for collagen by dephosphorylating Tyr(P)346, a regulatory site of Syk. J Biol Chem. 2017 Mar 10; 292(10):4360. PMID: 28283589.
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    30. Hayes V, Johnston I, Arepally GM, McKenzie SE, Cines DB, Rauova L, Poncz M. Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia. J Clin Invest. 2017 Mar 01; 127(3):1090-1098. PMID: 28218620.
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    31. Zhou Y, Abraham S, Renna S, Edelstein LC, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE. TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (Fc?RIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice. Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12):2315-2323. PMID: 27765766.
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    32. Reppschläger K, Gosselin J, Dangelmaier CA, Thomas DH, Carpino N, McKenzie SE, Kunapuli SP, Tsygankov AY. TULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of Syk. J Biol Chem. 2016 Oct 21; 291(43):22427-22441. PMID: 27609517.
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    33. Piatt R, Paul DS, Lee RH, McKenzie SE, Parise LV, Cowley DO, Cooley BC, Bergmeier W. Mice Expressing Low Levels of CalDAG-GEFI Exhibit Markedly Impaired Platelet Activation With Minor Impact on Hemostasis. Arterioscler Thromb Vasc Biol. 2016 Sep; 36(9):1838-46. PMID: 27417588.
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    34. Khandelwal S, Lee GM, Hester CG, Poncz M, McKenzie S, Sachais BS, Rauova L, Kelsoe G, Cines DB, Frank M, Arepally GM. The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21). Blood. 2016 Jul 13. PMID: 27412887.
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    35. McKenzie SE. Syk Inhibition in Ischemic Stroke. Arterioscler Thromb Vasc Biol. 2016 Jun; 36(6):1054-5. PMID: 27225787.
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    36. Buitrago L, Manne BK, Andre P, McKenzie S, Kunapuli S. Identification of novel Syk-independent functional roles of Fc?RIIa in platelet outside-in signaling using transgenic mice expressing human Fc?RIIa. Platelets. 2016 Jul; 27(5):488-90. PMID: 26809427.
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    37. Tutwiler V, Madeeva D, Ahn HS, Andrianova I, Hayes V, Zheng XL, Cines DB, McKenzie SE, Poncz M, Rauova L. Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia. Blood. 2016 Jan 28; 127(4):464-72. PMID: 26518435.
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    38. Zhou Y, Abraham S, Andre P, Edelstein LC, Shaw CA, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE. Anti-miR-148a regulates platelet Fc?RIIA signaling and decreases thrombosis in vivo in mice. Blood. 2015 Dec 24; 126(26):2871-81. PMID: 26516227.
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    39. Lin X, Zhang X, Guo J, Roberts CK, McKenzie S, Wu WC, Liu S, Song Y. Effects of Exercise Training on Cardiorespiratory Fitness and Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc. 2015 Jul; 4(7). PMID: 26116691.
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    40. Londin E, Loher P, Telonis AG, Quann K, Clark P, Jing Y, Hatzimichael E, Kirino Y, Honda S, Lally M, Ramratnam B, Comstock CE, Knudsen KE, Gomella L, Spaeth GL, Hark L, Katz LJ, Witkiewicz A, Rostami A, Jimenez SA, Hollingsworth MA, Yeh JJ, Shaw CA, McKenzie SE, Bray P, Nelson PT, Zupo S, Van Roosbroeck K, Keating MJ, Calin GA, Yeo C, Jimbo M, Cozzitorto J, Brody JR, Delgrosso K, Mattick JS, Fortina P, Rigoutsos I. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):E1106-15. PMID: 25713380.
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    41. Kostyak JC, Bhavanasi D, Liverani E, McKenzie SE, Kunapuli SP. Protein Kinase C d Deficiency Enhances Megakaryopoiesis and Recovery From Thrombocytopenia. Arterioscler Thromb Vasc Biol. 2014 Dec; 34(12):2579-85. PMID: 25359855.
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    42. McKenzie SE, Sachais BS. Advances in the pathophysiology and treatment of heparin-induced thrombocytopenia. Curr Opin Hematol. 2014 Sep; 21(5):380-7. PMID: 24992313.
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    43. Yeung J, Tourdot BE, Fernandez-Perez P, Vesci J, Ren J, Smyrniotis CJ, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, McKenzie SE, Holinstat M. Platelet 12-LOX is essential for Fc?RIIa-mediated platelet activation. Blood. 2014 Oct 2; 124(14):2271-9. PMID: 25100742.
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    44. Teruel-Montoya R, Kong X, Abraham S, Ma L, Kunapuli SP, Holinstat M, Shaw CA, McKenzie SE, Edelstein LC, Bray PF. MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression. PLoS One. 2014; 9(7):e102259. PMID: 25029370.
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    45. Londin ER, Hatzimichael E, Loher P, Edelstein L, Shaw C, Delgrosso K, Fortina P, Bray PF, McKenzie SE, Rigoutsos I. The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome. Biol Direct. 2014; 9(1):3. PMID: 24524654.
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    46. Simon LM, Edelstein LC, Nagalla S, Woodley AB, Chen ES, Kong X, Ma L, Fortina P, Kunapuli S, Holinstat M, McKenzie SE, Dong JF, Shaw CA, Bray PF. Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics. Blood. 2014 Apr 17; 123(16):e37-45. PMID: 24523238.
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    47. Pulte ED, McKenzie SE, Caro J, Ballas SK. Erythropoietin levels in patients with sickle cell disease do not correlate with known inducers of erythropoietin. Hemoglobin. 2014; 38(6):385-9. PMID: 25405915.
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    48. Bhatlekar S, Addya S, Salunek M, Orr CR, Surrey S, McKenzie S, Fields JZ, Boman BM. Identification of a Developmental Gene Expression Signature, Including HOX Genes, for the Normal Human Colonic Crypt Stem Cell Niche: Overexpression of the Signature Parallels Stem Cell Overpopulation During Colon Tumorigenesis. Stem Cells Dev. 2014 Jan 15; 23(2):167-79. PMID: 23980595.
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    49. Buitrago L, Bhavanasi D, Dangelmaier C, Manne BK, Badolia R, Borgognone A, Tsygankov AY, McKenzie SE, Kunapuli SP. Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms. J Biol Chem. 2013 Oct 4; 288(40):29160-9. PMID: 23960082.
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    50. Bray PF, McKenzie SE, Edelstein LC, Nagalla S, Delgrosso K, Ertel A, Kupper J, Jing Y, Londin E, Loher P, Chen HW, Fortina P, Rigoutsos I. The complex transcriptional landscape of the anucleate human platelet. BMC Genomics. 2013; 14:1. PMID: 23323973.
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    51. Zhi H, Rauova L, Hayes V, Gao C, Boylan B, Newman DK, McKenzie SE, Cooley BC, Poncz M, Newman PJ. Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. Blood. 2013 Mar 7; 121(10):1858-67. PMID: 23264598.
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    52. McKenzie SE. Monocytes in HIT: an evolving story. Blood. 2012 May 31; 119(22):5065-6. PMID: 22653954.
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    53. Stolla M, Stefanini L, André P, Ouellette TD, Reilly MP, McKenzie SE, Bergmeier W. CalDAG-GEFI deficiency protects mice in a novel model of Fc? RIIA-mediated thrombosis and thrombocytopenia. Blood. 2011 Jul 28; 118(4):1113-20. PMID: 21652673.
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    54. Reilly MP, Sinha U, André P, Taylor SM, Pak Y, Deguzman FR, Nanda N, Pandey A, Stolla M, Bergmeier W, McKenzie SE. PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model. Blood. 2011 Feb 17; 117(7):2241-6. PMID: 21088136.
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    55. Crow AR, Song S, Suppa SJ, Ma S, Reilly MP, Andre P, McKenzie SE, Lazarus AH. Amelioration of murine immune thrombocytopenia by CD44 antibodies: a potential therapy for ITP? Blood. 2011 Jan 20; 117(3):971-4. PMID: 21045192.
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    56. Flores M, Desai DD, Downie M, Liang B, Reilly MP, McKenzie SE, Clynes R. Dominant expression of the inhibitory FcgammaRIIB prevents antigen presentation by murine plasmacytoid dendritic cells. J Immunol. 2009 Dec 1; 183(11):7129-39. PMID: 19917701.
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    57. McKenzie SE, Reilly MP. The clot thickens (or not). Blood. 2009 Aug 27; 114(9):1722-3. PMID: 19713476.
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    58. Kline A, Mackley A, Taylor SM, McKenzie SE, Paul DA. Thrombopoietin following transfusion of platelets in preterm neonates. Platelets. 2008 Sep; 19(6):428-31. PMID: 18925510.
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    59. Cines DB, Rauova L, Arepally G, Reilly MP, McKenzie SE, Sachais BS, Poncz M. Heparin-induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly. J Clin Apher. 2007 Feb; 22(1):31-6. PMID: 17285619.
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    60. Liu ML, Reilly MP, Casasanto P, McKenzie SE, Williams KJ. Cholesterol enrichment of human monocyte/macrophages induces surface exposure of phosphatidylserine and the release of biologically-active tissue factor-positive microvesicles. Arterioscler Thromb Vasc Biol. 2007 Feb; 27(2):430-5. PMID: 17158353.
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    61. Worth RG, Chien CD, Chien P, Reilly MP, McKenzie SE, Schreiber AD. Platelet FcgammaRIIA binds and internalizes IgG-containing complexes. Exp Hematol. 2006 Nov; 34(11):1490-5. PMID: 17046568.
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    62. Tan Sardjono C, Mottram PL, van de Velde NC, Powell MS, Power D, Slocombe RF, Wicks IP, Campbell IK, McKenzie SE, Brooks M, Stevenson AW, Hogarth PM. Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fcgamma receptor IIa-transgenic mice. Arthritis Rheum. 2005 Oct; 52(10):3220-9. PMID: 16200626.
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    63. van Royen-Kerkhof A, Sanders EA, Walraven V, Voorhorst-Ogink M, Saeland E, Teeling JL, Gerritsen A, van Dijk MA, Kuis W, Rijkers GT, Vitale L, Keler T, McKenzie SE, Leusen JH, van de Winkel JG. A novel human CD32 mAb blocks experimental immune haemolytic anaemia in FcgammaRIIA transgenic mice. Br J Haematol. 2005 Jul; 130(1):130-7. PMID: 15982355.
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    64. Suvarna S, Rauova L, McCracken EK, Goss CM, Sachais BS, McKenzie SE, Reilly MP, Gunn MD, Cines DB, Poncz M, Arepally G. PF4/heparin complexes are T cell-dependent antigens. Blood. 2005 Aug 1; 106(3):929-31. PMID: 15845897.
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    65. McKenzie SE, Reilly MP. Heparin-induced thrombocytopenia and other immune thrombocytopenias: lessons from mouse models. Semin Thromb Hemost. 2004 Oct; 30(5):559-68. PMID: 15497098.
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    66. Rauova L, Poncz M, McKenzie SE, Reilly MP, Arepally G, Weisel JW, Nagaswami C, Cines DB, Sachais BS. Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia. Blood. 2005 Jan 1; 105(1):131-8. PMID: 15304392.
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    67. Coleman MM, Spear ML, Finkelstein M, Leef KH, Pearlman SA, Chien C, Taylor SM, McKenzie SE. Short-term use of umbilical artery catheters may not be associated with increased risk for thrombosis. Pediatrics. 2004 Apr; 113(4):770-4. PMID: 15060226.
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    68. Cines DB, McKenzie SE, Siegel DL. Mechanisms of action of therapeutics in idiopathic thrombocytopenic purpura. J Pediatr Hematol Oncol. 2003 Dec; 25 Suppl 1:S52-6. PMID: 14668641.
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    69. Guida JD, Kunig AM, Leef KH, McKenzie SE, Paul DA. Platelet count and sepsis in very low birth weight neonates: is there an organism-specific response? Pediatrics. 2003 Jun; 111(6 Pt 1):1411-5. PMID: 12777561.
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    70. Reilly MP, McKenzie SE. Insights from mouse models of heparin-induced thrombocytopenia and thrombosis. Curr Opin Hematol. 2002 Sep; 9(5):395-400. PMID: 12172457.
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    71. Reilly MP, McKenzie SE. Mechanisms of action of IVIg: physiology of Fc receptors. Vox Sang. 2002 Aug; 83 Suppl 1:57-63. PMID: 12617105.
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    72. Su HJ, Surrey S, McKenzie SE, Fortina P, Graves DJ. Kinetics of heterogeneous hybridization on indium tin oxide surfaces with and without an applied potential. Electrophoresis. 2002 May; 23(10):1551-7. PMID: 12116168.
      Citations:    
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