Thomas Jefferson University

Sergio Jimenez

TitleProfessor
InstitutionThomas Jefferson University
DepartmentDermatology
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-5326
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    R01AM015091     (JIMENEZ, SERGIO A)Apr 1, 1977 - Nov 30, 1987
    NIH
    ARTICULAR CARTILAGE PRESERVATION AND TRANSPLANTATION
    Role: Principal Investigator
    R01AR015091     (JIMENEZ, SERGIO A)Apr 1, 1977 - Nov 30, 1987
    NIH
    ARTICULAR CARTILAGE PRESERVATION AND TRANSPLANTATION
    Role: Principal Investigator
    R01AM019616     (JIMENEZ, SERGIO A)Jul 1, 1978 - Jun 30, 1990
    NIH
    BIOCHEMICAL AND VASCULAR ALTERATIONS IN SCLERODERMA
    Role: Principal Investigator
    R01AR019616     (JIMENEZ, SERGIO A)Jul 1, 1978 - Mar 31, 2012
    NIH
    Biochemical and Vascular Alterations in Scleroderma
    Role: Principal Investigator
    R01HL031650     (JIMENEZ, SERGIO A)Sep 30, 1983 - Sep 29, 1986
    NIH
    CONNECTIVE TISSUE REGULATION IN PULMONARY FIBROSIS
    Role: Principal Investigator
    R01AM032564     (JIMENEZ, SERGIO A)Dec 1, 1984 - Nov 30, 1987
    NIH
    COLLAGEN METABOLISM IN A MODEL FOR SCLERODERMA
    Role: Principal Investigator
    R01AR032564     (JIMENEZ, SERGIO A)Dec 1, 1984 - Jun 30, 2005
    NIH
    COLLAGEN METABOLISM IN A MODEL FOR SCLERODERMA
    Role: Principal Investigator
    R01HL041214     (JIMENEZ, SERGIO A)Jul 1, 1988 - Apr 30, 1994
    NIH
    LUNG FIBROSIS--MECHANISMS OF COLLAGEN GENE EXPRESSION
    Role: Principal Investigator
    P01AR039740     (JIMENEZ, SERGIO A)Dec 1, 1988 - Mar 31, 2008
    NIH
    Molecular Biology of Osteoarthritis
    Role: Principal Investigator
    T32AR007583     (JIMENEZ, SERGIO A)Jul 1, 1994 - Dec 29, 2009
    NIH
    TRAINING IN MOLECULAR RHEUMATOLOGY AND ORTHOPEDICS
    Role: Principal Investigator
    R01AR055660     (JIMENEZ, SERGIO A)Jul 1, 2008 - May 31, 2014
    NIH
    Role of Caveolin in Scleroderma Tissue Fibrosis and Vasculopathy
    Role: Principal Investigator
    R21AR059970     (JIMENEZ, SERGIO A)Aug 9, 2010 - Dec 31, 2012
    NIH
    Identification of Novel Markers for Systemic Sclerosis Employing Proteomics
    Role: Principal Investigator
    R21AR061680     (JIMENEZ, SERGIO A)Sep 24, 2012 - Dec 31, 2014
    NIH
    Role of toll like receptors (TLRs)in Gd contrast agent induced skin fibrosis
    Role: Principal Investigator
    R21AR065638     (JIMENEZ, SERGIO A)Apr 1, 2014 - Mar 31, 2016
    NIH
    Role of TRPV channels in the pathogenesis of Systemic Sclerosis vasculopathy
    Role: Principal Investigator
    R21AR071644     (JIMENEZ, SERGIO A)Apr 10, 2017 - Feb 28, 2019
    NIH
    Serum Exosome MicroRNA in Systemic Sclerosis
    Role: Principal Investigator
    R21AR074016     (JIMENEZ, SERGIO A)Jul 1, 2019 - May 31, 2021
    NIH
    Aptamer Proteomic Analysis of Systemic Sclerosis Serum Exosomes
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Somashekar A, Squires S, Benedetto AV, Griffin TD, Jimenez SA, Mendoza FA. Nodular scleroderma: Characterization of a distinct clinical phenotype. Am J Med Sci. 2025 Apr; 369(4):423-426. PMID: 39326737.
      Citations:    
    2. Piera-Velazquez S, Fortina P, Jimenez SA. Comparison of serum exosome miRNA from patients with Raynaud's phenomenon with positive and negative serum antinuclear antibodies. Clin Exp Rheumatol. 2024 Aug; 42(8):1629-1634. PMID: 39152754.
      Citations:    
    3. Hitraya E, Gaidarova S, Piera-Velazquez S, Jimenez SA. COL1A1 proximal promoter topology regulates its transcriptional response to transforming growth factor ?. Connect Tissue Res. 2024 03; 65(2):161-169. PMID: 38436275.
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    4. Jimenez SA, Piera-Velazquez S. Cellular Transdifferentiation: A Crucial Mechanism of Fibrosis in Systemic Sclerosis. Curr Rheumatol Rev. 2024; 20(4):388-404. PMID: 37921216.
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    5. Mendoza FA, Allawh T, Jimenez SA. Pharmacological treatment of systemic sclerosis-associated interstitial lung disease: an updated review and current approach to patient care. Clin Exp Rheumatol. 2023 Aug; 41(8):1704-1712. PMID: 37382458.
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    6. Jimenez SA, Piera-Velazquez S. Probable role of exosomes in the extension of fibrotic alterations from affected to normal cells in systemic sclerosis. Rheumatology (Oxford). 2023 03 01; 62(3):999-1008. PMID: 35944210.
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    7. Piera-Velazquez S, Dillon ST, Gu X, Libermann TA, Jimenez SA. Aptamer proteomics of serum exosomes from patients with Primary Raynaud's and patients with Raynaud's at risk of evolving into Systemic Sclerosis. PLoS One. 2022; 17(12):e0279461. PMID: 36548367.
      Citations:    
    8. Mendoza FA, DiMarino A, Cohen S, Adkins C, Abdelbaki S, Rattan S, Cao C, Denuna-Rivera S, Jimenez SA. Treatment of Severe Swallowing Dysfunction in Systemic Sclerosis with IVIG: Role of Antimuscarinic Antibodies. J Clin Med. 2022 Nov 10; 11(22). PMID: 36431141.
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    9. Mendoza FA, Jimenez SA. Serine/threonine kinase inhibition as antifibrotic therapy: transforming growth factor-? and Rho kinase inhibitors. Rheumatology (Oxford). 2022 04 11; 61(4):1354-1365. PMID: 34664623.
      Citations:    
    10. Mendoza FA, Bagley J, Gochfeld M, Dalakas MC, Farber JL, Jimenez SA. Progressive multifocal fibrosing neuropathy: description of a novel disease. Acta Neuropathol Commun. 2022 03 16; 10(1):34. PMID: 35296359.
      Citations:    
    11. Piera-Velazquez S, Jimenez SA. Oxidative Stress Induced by Reactive Oxygen Species (ROS) and NADPH Oxidase 4 (NOX4) in the Pathogenesis of the Fibrotic Process in Systemic Sclerosis: A Promising Therapeutic Target. J Clin Med. 2021 Oct 19; 10(20). PMID: 34682914.
      Citations:    
    12. Abignano G, Hermes H, Piera-Velazquez S, Addya S, Del Galdo F, Jimenez SA. Global gene expression analysis of systemic sclerosis myofibroblasts demonstrates a marked increase in the expression of multiple NBPF genes. Sci Rep. 2021 10 14; 11(1):20435. PMID: 34650102.
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    13. Mendoza FA, Piera-Velazquez S, Jimenez SA. Tyrosine kinases in the pathogenesis of tissue fibrosis in systemic sclerosis and potential therapeutic role of their inhibition. Transl Res. 2021 05; 231:139-158. PMID: 33422651.
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    14. Piera-Velazquez S, Mendoza FA, Addya S, Pomante D, Jimenez SA. Increased expression of interferon regulated and antiviral response genes in CD31+/CD102+ lung microvascular endothelial cells from systemic sclerosis patients with end-stage interstitial lung disease. Clin Exp Rheumatol. 2021 Nov-Dec; 39(6):1298-1306. PMID: 33253099.
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    15. Piera-Velazquez S, Wermuth PJ, Gomez-Reino JJ, Varga J, Jimenez SA. Chemical exposure-induced systemic fibrosing disorders: Novel insights into systemic sclerosis etiology and pathogenesis. Semin Arthritis Rheum. 2020 12; 50(6):1226-1237. PMID: 33059296.
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    16. Wermuth PJ, Jimenez SA. Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as "EXOSOMES". Autoimmun Rev. 2020 Oct; 19(10):102644. PMID: 32801042.
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    17. Jaeger VK, Tikly M, Xu D, Siegert E, Hachulla E, Air? P, Valentini G, Matucci Cerinic M, Distler O, Cozzi F, Carreira P, Allanore Y, M?ller-Ladner U, Ananieva LP, Balbir-Gurman A, Distler JHW, Czirj?k L, Li M, Henes J, Jimenez SA, Smith V, Damjanov N, Denton CP, DelGaldo F, Saketkoo LA, Walker UA. Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study. Rheumatology (Oxford). 2020 Jul 01; 59(7):1684-1694. PMID: 31680161.
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    18. Wasson CW, Abignano G, Hermes H, Malaab M, Ross RL, Jimenez SA, Chang HY, Feghali-Bostwick CA, Del Galdo F. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Ann Rheum Dis. 2020 04; 79(4):507-517. PMID: 32041748.
      Citations:    
    19. Henry TW, Mendoza FA, Jimenez SA. Role of microRNA in the pathogenesis of systemic sclerosis tissue fibrosis and vasculopathy. Autoimmun Rev. 2019 Nov; 18(11):102396. PMID: 31520794.
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    20. Mendoza FA, Lee-Ching C, Jimenez SA. Recurrence of progressive skin involvement following discontinuation or dose reduction of Mycophenolate Mofetil treatment in patients with diffuse Systemic Sclerosis. Semin Arthritis Rheum. 2020 02; 50(1):135-139. PMID: 31311679.
      Citations:    
    21. Piera-Velazquez S, Jimenez SA. Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases. Physiol Rev. 2019 04 01; 99(2):1281-1324. PMID: 30864875.
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    22. Wermuth PJ, Mendoza FA, Jimenez SA. Abrogation of transforming growth factor-?-induced tissue fibrosis in mice with a global genetic deletion of Nox4. Lab Invest. 2019 04; 99(4):470-482. PMID: 30470772.
      Citations:    
    23. Wermuth PJ, Piera-Velazquez S, Jimenez SA. Identification of novel systemic sclerosis biomarkers employing aptamer proteomic analysis. Rheumatology (Oxford). 2018 10 01; 57(10):1698-1706. PMID: 29140474.
      Citations:    
    24. Piera-Velazquez S, Jimenez SA. Simultaneous inhibition of c-Abl and Src kinases abrogates the exaggerated expression of profibrotic genes in cultured systemic sclerosis dermal fibroblasts. Clin Exp Rheumatol. 2018 Jul-Aug; 36 Suppl 113(4):36-44. PMID: 30277861.
      Citations:    
    25. Wermuth PJ, Piera-Velazquez S, Rosenbloom J, Jimenez SA. Existing and novel biomarkers for precision medicine in systemic sclerosis. Nat Rev Rheumatol. 2018 07; 14(7):421-432. PMID: 29789665.
      Citations:    
    26. Wermuth PJ, Jimenez SA. Abrogation of transforming growth factor-?-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib). PLoS One. 2018; 13(5):e0196559. PMID: 29718973.
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    27. Sacchetti C, Bai Y, Stanford SM, Di Benedetto P, Cipriani P, Santelli E, Piera-Velazquez S, Chernitskiy V, Kiosses WB, Ceponis A, Kaestner KH, Boin F, Jimenez SA, Giacomelli R, Zhang ZY, Bottini N. PTP4A1 promotes TGF? signaling and fibrosis in systemic sclerosis. Nat Commun. 2017 10 20; 8(1):1060. PMID: 29057934.
      Citations:    
    28. Wermuth PJ, Carney KR, Mendoza FA, Piera-Velazquez S, Jimenez SA. Endothelial cell-specific activation of transforming growth factor-? signaling in mice induces cutaneous, visceral, and microvascular fibrosis. Lab Invest. 2017 07; 97(7):806-818. PMID: 28346399.
      Citations:    
    29. Cox LA, Webster GF, Piera-Velazquez S, Jimenez SA. Multiplex assessment of serum cytokine and chemokine levels in idiopathic morphea and vitamin K1-induced morphea. Clin Rheumatol. 2017 May; 36(5):1173-1178. PMID: 28220270.
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    30. Kumar S, Singh J, Rattan S, DiMarino AJ, Cohen S, Jimenez SA. Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. Aliment Pharmacol Ther. 2017 04; 45(7):883-898. PMID: 28185291.
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    31. Wermuth PJ, Piera-Velazquez S, Jimenez SA. Exosomes isolated from serum of systemic sclerosis patients display alterations in their content of profibrotic and antifibrotic microRNA and induce a profibrotic phenotype in cultured normal dermal fibroblasts. Clin Exp Rheumatol. 2017 Sep-Oct; 35 Suppl 106(4):21-30. PMID: 28094758.
      Citations:    
    32. Rosenbloom J, Macarak E, Piera-Velazquez S, Jimenez SA. Human Fibrotic Diseases: Current Challenges in Fibrosis Research. Methods Mol Biol. 2017; 1627:1-23. PMID: 28836191.
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    33. Wermuth PJ, Li Z, Mendoza FA, Jimenez SA. Stimulation of Transforming Growth Factor-?1-Induced Endothelial-To-Mesenchymal Transition and Tissue Fibrosis by Endothelin-1 (ET-1): A Novel Profibrotic Effect of ET-1. PLoS One. 2016; 11(9):e0161988. PMID: 27583804.
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    34. Kumar S, Singh J, Kedika R, Mendoza F, Jimenez SA, Blomain ES, DiMarino AJ, Cohen S, Rattan S. Role of muscarinic-3 receptor antibody in systemic sclerosis: correlation with disease duration and effects of IVIG. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G1052-60. PMID: 27173508.
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    35. Piera-Velazquez S, Mendoza FA, Jimenez SA. Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases. J Clin Med. 2016 Apr 11; 5(4). PMID: 27077889.
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    36. Jimenez SA, Piera-Velazquez S. Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality? Matrix Biol. 2016 04; 51:26-36. PMID: 26807760.
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    37. Mendoza FA, Mansoor M, Jimenez SA. Treatment of Rapidly Progressive Systemic Sclerosis: Current and Futures Perspectives. Expert Opin Orphan Drugs. 2016; 4(1):31-47. PMID: 27812432.
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    38. Mendoza FA, Bai R, Kebede AG, Jimenez SA. Severe eosinophilic fasciitis: comparison of treatment with D-penicillamine plus corticosteroids vs. corticosteroids alone. Scand J Rheumatol. 2016; 45(2):129-34. PMID: 26525956.
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    39. Londin E, Loher P, Telonis AG, Quann K, Clark P, Jing Y, Hatzimichael E, Kirino Y, Honda S, Lally M, Ramratnam B, Comstock CE, Knudsen KE, Gomella L, Spaeth GL, Hark L, Katz LJ, Witkiewicz A, Rostami A, Jimenez SA, Hollingsworth MA, Yeh JJ, Shaw CA, McKenzie SE, Bray P, Nelson PT, Zupo S, Van Roosbroeck K, Keating MJ, Calin GA, Yeo C, Jimbo M, Cozzitorto J, Brody JR, Delgrosso K, Mattick JS, Fortina P, Rigoutsos I. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):E1106-15. PMID: 25713380.
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    40. Carriba P, Jimenez S, Navarro V, Moreno-Gonzalez I, Barneda-Zahonero B, Moubarak RS, Lopez-Soriano J, Gutierrez A, Vitorica J, Comella JX. Amyloid-? reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFa from neuronal protection to death. Cell Death Dis. 2015 Feb 12; 6:e1639. PMID: 25675299.
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    41. Wermuth PJ, Jimenez SA. The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases. Clin Transl Med. 2015; 4:2. PMID: 25852818.
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    42. Piera-Velazquez S, Jimenez SA. Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis. Curr Rheumatol Rep. 2015 Jan; 17(1):473. PMID: 25475596.
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    43. Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Air? P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Balbir Gurman A, Braun-Moscovici Y, Damjanov N, Ananieva LP, Scorza R, Jimenez S, Busquets J, Li M, M?ller-Ladner U, Kahan A, Distler O, Allanore Y. A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study. Ann Rheum Dis. 2016 Jan; 75(1):163-9. PMID: 25342760.
      Citations:    
    44. Dumit VI, K?ttner V, K?ppler J, Piera-Velazquez S, Jimenez SA, Bruckner-Tuderman L, Uitto J, Dengjel J. Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts. J Invest Dermatol. 2014 Sep; 134(9):2321-2330. PMID: 24496236.
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    45. Wermuth PJ, Jimenez SA. Induction of a type I interferon signature in normal human monocytes by gadolinium-based contrast agents: comparison of linear and macrocyclic agents. Clin Exp Immunol. 2014 Jan; 175(1):113-25. PMID: 24111526.
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    46. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, M?ller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Ellen Csuka M, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE. 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative. Ann Rheum Dis. 2013 Nov; 72(11):1747-55. PMID: 24092682.
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    47. Manne J, Markova M, Siracusa LD, Jimenez SA. Collagen content in skin and internal organs of the tight skin mouse: an animal model of scleroderma. Biochem Res Int. 2013; 2013:436053. PMID: 24260716.
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    48. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, M?ller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Csuka ME, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE. 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum. 2013 Nov; 65(11):2737-47. PMID: 24122180.
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    49. Jimenez SA. Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis. ISRN Rheumatol. 2013 Sep 23; 2013:835948. PMID: 24175099.
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    50. Jimenez SA, Piera-Velazquez S. Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of systemic sclerosis and Sj?gren's syndrome. Autoimmun Rev. 2013 Sep; 12(11):1046-51. PMID: 23684698.
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    51. Busquets J, Lee Y, Santamarina L, Federman JL, Abel A, Del Galdo F, Eagle RC, Jimenez SA. Acute retinal artery occlusion in systemic sclerosis: a rare manifestation of systemic sclerosis fibroproliferative vasculopathy. Semin Arthritis Rheum. 2013 Oct; 43(2):204-8. PMID: 23433487.
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    52. Manterola L, Hernando-Rodr?guez M, Ruiz A, Apraiz A, Arrizabalaga O, Vell?n L, Alberdi E, Cavaliere F, Lacerda HM, Jimenez S, Parada LA, Matute C, Zugaza JL. 1-42 ?-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death. Transl Psychiatry. 2013 Jan 22; 3:e219. PMID: 23340502.
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    53. Rosenbloom J, Mendoza FA, Jimenez SA. Strategies for anti-fibrotic therapies. Biochim Biophys Acta. 2013 Jul; 1832(7):1088-103. PMID: 23266403.
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    54. Mendoza FA, Purohit S, Kenyon L, Jimenez SA. Severe eosinophilic syndrome associated with the use of probiotic supplements: a new entity? Case Rep Rheumatol. 2012; 2012:934324. PMID: 23259129.
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    55. Li Z, Wermuth PJ, Benn BS, Lisanti MP, Jimenez SA. Caveolin-1 deficiency induces spontaneous endothelial-to-mesenchymal transition in murine pulmonary endothelial cells in vitro. Am J Pathol. 2013 Feb; 182(2):325-31. PMID: 23195429.
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    56. Marc?n R, Jimenez S, Fern?ndez A, Galeano C, Villafruela JJ, Burgos FJ, Quereda C. The effects of mineral metabolism markers on renal transplant outcomes. Transplant Proc. 2012 Nov; 44(9):2567-9. PMID: 23146456.
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    57. Singh J, Cohen S, Mehendiratta V, Mendoza F, Jimenez SA, Dimarino AJ, Rattan S. Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function. Gastroenterology. 2012 Nov; 143(5):1308-1318. PMID: 22864255.
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    58. Lee CG, Herzog EL, Ahangari F, Zhou Y, Gulati M, Lee CM, Peng X, Feghali-Bostwick C, Jimenez SA, Varga J, Elias JA. Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-?1 signaling. J Immunol. 2012 Sep 01; 189(5):2635-44. PMID: 22826322.
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    59. Mendoza FA, Keyes-Elstein LL, Jimenez SA. Systemic sclerosis disease modification clinical trials design: quo vadis? Arthritis Care Res (Hoboken). 2012 Jul; 64(7):945-54. PMID: 22422541.
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    60. Piera-Velazquez S, Jimenez SA. Molecular mechanisms of endothelial to mesenchymal cell transition (EndoMT) in experimentally induced fibrotic diseases. Fibrogenesis Tissue Repair. 2012; 5(Suppl 1):S7. PMID: 23259736.
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    61. Wermuth PJ, Jimenez SA. Gadolinium compounds signaling through TLR4 and TLR7 in normal human macrophages: establishment of a proinflammatory phenotype and implications for the pathogenesis of nephrogenic systemic fibrosis. J Immunol. 2012 Jul 01; 189(1):318-27. PMID: 22649203.
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    62. Mendoza FA, Nagle SJ, Lee JB, Jimenez SA. A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. J Rheumatol. 2012 Jun; 39(6):1241-7. PMID: 22467932.
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    63. Fransen J, Johnson SR, van den Hoogen F, Baron M, Allanore Y, Carreira PE, Czirj?k L, Denton CP, Distler O, Furst DE, Gabrielli A, Herrick A, Inanc M, Kahaleh B, Kowal-Bielecka O, Medsger TA, Mueller-Ladner U, Riemekasten G, Sierakowski S, Valentini G, Veale D, Vonk MC, Walker U, Chung L, Clements PJ, Collier DH, Csuka ME, Jimenez S, Merkel PA, Seibold JR, Silver R, Steen V, Tyndall A, Matucci-Cerinic M, Pope JE, Khanna D. Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise. Arthritis Care Res (Hoboken). 2012 Mar; 64(3):351-7. PMID: 22052558.
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    64. Derk CT, Huaman G, Littlejohn J, Otieno F, Jimenez S. Predictors of early mortality in systemic sclerosis: a case-control study comparing early versus late mortality in systemic sclerosis. Rheumatol Int. 2012 Dec; 32(12):3841-4. PMID: 22193226.
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    65. Tsou PS, Talia NN, Pinney AJ, Kendzicky A, Piera-Velazquez S, Jimenez SA, Seibold JR, Phillips K, Koch AE. Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts. Arthritis Rheum. 2012 Jun; 64(6):1978-89. PMID: 22161819.
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    66. Wermuth PJ, Addya S, Jimenez SA. Effect of protein kinase C delta (PKC-d) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro. PLoS One. 2011; 6(11):e27110. PMID: 22096525.
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    67. Fernandez AM, Jimenez S, Mecha M, D?vila D, Guaza C, Vitorica J, Torres-Aleman I. Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology. Mol Psychiatry. 2012 Jul; 17(7):705-18. PMID: 22005929.
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    68. Lee YH, Sahu J, O'Brien MS, D'Agati VD, Jimenez SA. Scleroderma renal crisis-like acute renal failure associated with mucopolysaccharide accumulation in renal vessels in a patient with scleromyxedema. J Clin Rheumatol. 2011 Sep; 17(6):318-22. PMID: 21869708.
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    69. Li Z, Jimenez SA. Protein kinase Cd and c-Abl kinase are required for transforming growth factor ? induction of endothelial-mesenchymal transition in vitro. Arthritis Rheum. 2011 Aug; 63(8):2473-83. PMID: 21425122.
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    70. Piera-Velazquez S, Li Z, Jimenez SA. Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders. Am J Pathol. 2011 Sep; 179(3):1074-80. PMID: 21763673.
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    71. Velasco G, Savarese V, Sandorfi N, Jimenez SA, Jabbour S. 46, XX SRY-positive male syndrome presenting with primary hypogonadism in the setting of scleroderma. Endocr Pract. 2011 Jan-Feb; 17(1):95-8. PMID: 20841307.
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    72. Del Galdo F, Wermuth PJ, Addya S, Fortina P, Jimenez SA. NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of nephrogenic systemic fibrosis. Ann Rheum Dis. 2010 Nov; 69(11):2024-33. PMID: 20959327.
      Citations:    
    73. Roman-Blas J, Dion AS, Seghatoleslami MR, Giunta K, Oca P, Jimenez SA, Williams CJ. MED and PSACH COMP mutations affect chondrogenesis in chicken limb bud micromass cultures. J Cell Physiol. 2010 Sep; 224(3):817-26. PMID: 20578249.
      Citations:    
    74. Del Galdo F, Shaw MA, Jimenez SA. Proteomic analysis identification of a pattern of shared alterations in the secretome of dermal fibroblasts from systemic sclerosis and nephrogenic systemic fibrosis. Am J Pathol. 2010 Oct; 177(4):1638-46. PMID: 20724591.
      Citations:    
    75. Piera-Velazquez S, Louneva N, Fertala J, Wermuth PJ, Del Galdo F, Jimenez SA. Persistent activation of dermal fibroblasts from patients with gadolinium-associated nephrogenic systemic fibrosis. Ann Rheum Dis. 2010 Nov; 69(11):2017-23. PMID: 20570839.
      Citations:    
    76. Busquets J, Del Galdo F, Kissin EY, Jimenez SA. Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: an objective outcome measure for clinical trials? Rheumatology (Oxford). 2010 Jun; 49(6):1069-75. PMID: 20202926.
      Citations:    
    77. Rosenbloom J, Castro SV, Jimenez SA. Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies. Ann Intern Med. 2010 Feb 02; 152(3):159-66. PMID: 20124232.
      Citations:    
    78. Castro SV, Jimenez SA. Biomarkers in systemic sclerosis. Biomark Med. 2010 Feb; 4(1):133-47. PMID: 20387310.
      Citations:    
    79. Hou Y, Rabquer BJ, Gerber ML, Del Galdo F, Jimenez SA, Haines GK, Barr WG, Massa MC, Seibold JR, Koch AE. Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion. Ann Rheum Dis. 2010 Jan; 69(1):249-54. PMID: 19153103.
      Citations:    
    80. Newton BB, Jimenez SA. Mechanism of NSF: New evidence challenging the prevailing theory. J Magn Reson Imaging. 2009 Dec; 30(6):1277-83. PMID: 19937925.
      Citations:    
    81. Gaudet P, Lane L, Fey P, Bridge A, Poux S, Auchincloss A, Axelsen K, Braconi Quintaje S, Boutet E, Brown P, Coudert E, Datta RS, de Lima WC, de Oliveira Lima T, Duvaud S, Farriol-Mathis N, Ferro Rojas S, Feuermann M, Gateau A, Hinz U, Hulo C, James J, Jimenez S, Jungo F, Keller G, Lemercier P, Lieberherr D, Moinat M, Nikolskaya A, Pedruzzi I, Rivoire C, Roechert B, Schneider M, Stanley E, Tognolli M, Sj?lander K, Bougueleret L, Chisholm RL, Bairoch A. Collaborative annotation of genes and proteins between UniProtKB/Swiss-Prot and dictyBase. Database (Oxford). 2009; 2009:bap016. PMID: 20157489.
      Citations:    
    82. Singh J, Mehendiratta V, Del Galdo F, Jimenez SA, Cohen S, DiMarino AJ, Rattan S. Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1206-13. PMID: 19779020.
      Citations:    
    83. Schulz SW, O'Brien M, Maqsood M, Sandorfi N, Del Galdo F, Jimenez SA. Improvement of severe systemic sclerosis-associated gastric antral vascular ectasia following immunosuppressive treatment with intravenous cyclophosphamide. J Rheumatol. 2009 Aug; 36(8):1653-6. PMID: 19605670.
      Citations:    
    84. Herrero-Beaumont G, Roman-Blas JA, Casta?eda S, Jimenez SA. Primary osteoarthritis no longer primary: three subsets with distinct etiological, clinical, and therapeutic characteristics. Semin Arthritis Rheum. 2009 Oct; 39(2):71-80. PMID: 19589561.
      Citations:    
    85. Rabquer BJ, Hou Y, Del Galdo F, Kenneth Haines G, Gerber ML, Jimenez SA, Seibold JR, Koch AE. The proadhesive phenotype of systemic sclerosis skin promotes myeloid cell adhesion via ICAM-1 and VCAM-1. Rheumatology (Oxford). 2009 Jul; 48(7):734-40. PMID: 19439502.
      Citations:    
    86. Sotgia F, Del Galdo F, Casimiro MC, Bonuccelli G, Mercier I, Whitaker-Menezes D, Daumer KM, Zhou J, Wang C, Katiyar S, Xu H, Bosco E, Quong AA, Aronow B, Witkiewicz AK, Minetti C, Frank PG, Jimenez SA, Knudsen ES, Pestell RG, Lisanti MP. Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts. Am J Pathol. 2009 Mar; 174(3):746-61. PMID: 19234134.
      Citations:    
    87. Schulz SW, Bober M, Johnson C, Braverman N, Jimenez SA. Maternal mixed connective tissue disease and offspring with chondrodysplasia punctata. Semin Arthritis Rheum. 2010 Apr; 39(5):410-6. PMID: 19110299.
      Citations:    
    88. Del Galdo F, Lisanti MP, Jimenez SA. Caveolin-1, transforming growth factor-beta receptor internalization, and the pathogenesis of systemic sclerosis. Curr Opin Rheumatol. 2008 Nov; 20(6):713-9. PMID: 18949888.
      Citations:    
    89. Derk CT, Huaman G, Jimenez SA. A retrospective randomly selected cohort study of D-penicillamine treatment in rapidly progressive diffuse cutaneous systemic sclerosis of recent onset. Br J Dermatol. 2008 May; 158(5):1063-8. PMID: 18284395.
      Citations:    
    90. Roman-Blas JA, Jimenez SA. Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis. Int Rev Immunol. 2008; 27(5):351-74. PMID: 18853343.
      Citations:    
    91. Kypriotou M, Beauchef G, Chadjichristos C, Widom R, Renard E, Jimenez SA, Korn J, Maquart FX, Oddos T, Von Stetten O, Pujol JP, Gal?ra P. Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors. J Biol Chem. 2007 Nov 02; 282(44):32000-14. PMID: 17698844.
      Citations:    
    92. Roman-Blas JA, Stokes DG, Jimenez SA. Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. Osteoarthritis Cartilage. 2007 Dec; 15(12):1367-77. PMID: 17604656.
      Citations:    
    93. Otieno FG, Lopez AM, Jimenez SA, Gentiletti J, Artlett CM. Allograft inflammatory factor-1 and tumor necrosis factor single nucleotide polymorphisms in systemic sclerosis. Tissue Antigens. 2007 Jun; 69(6):583-91. PMID: 17498268.
      Citations:    
    94. Shah RM, Jimenez S, Wechsler R. Significance of ground-glass opacity on HRCT in long-term follow-up of patients with systemic sclerosis. J Thorac Imaging. 2007 May; 22(2):120-4. PMID: 17527113.
      Citations:    
    95. Piera-Velazquez S, Hawkins DF, Whitecavage MK, Colter DC, Stokes DG, Jimenez SA. Regulation of the human SOX9 promoter by Sp1 and CREB. Exp Cell Res. 2007 Apr 01; 313(6):1069-79. PMID: 17289023.
      Citations:    
    96. Del Galdo F, Artlett CM, Jimenez SA. The role of allograft inflammatory factor 1 in systemic sclerosis. Curr Opin Rheumatol. 2006 Nov; 18(6):588-93. PMID: 17053503.
      Citations:    
    97. Roman-Blas JA, Jimenez SA. NF-kappaB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis. Osteoarthritis Cartilage. 2006 Sep; 14(9):839-48. PMID: 16730463.
      Citations:    
    98. Derk CT, Rasheed M, Artlett CM, Jimenez SA. A cohort study of cancer incidence in systemic sclerosis. J Rheumatol. 2006 Jun; 33(6):1113-6. PMID: 16622904.
      Citations:    
    99. Derk CT, Jimenez SA. Acute myocardial infarction in systemic sclerosis patients: a case series. Clin Rheumatol. 2007 Jun; 26(6):965-8. PMID: 16521051.
      Citations:    
    100. Mendoza FA, Artlett CM, Sandorfi N, Latinis K, Piera-Velazquez S, Jimenez SA. Description of 12 cases of nephrogenic fibrosing dermopathy and review of the literature. Semin Arthritis Rheum. 2006 Feb; 35(4):238-49. PMID: 16461069.
      Citations:    
    101. Derk CT, Artlett CM, Jimenez SA. Morbidity and mortality of patients diagnosed with systemic sclerosis after the age of 75: a nested case-control study. Clin Rheumatol. 2006 Nov; 25(6):831-4. PMID: 16435160.
      Citations:    
    102. Pritzker KP, Gay S, Jimenez SA, Ostergaard K, Pelletier JP, Revell PA, Salter D, van den Berg WB. Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis Cartilage. 2006 Jan; 14(1):13-29. PMID: 16242352.
      Citations:    
    103. Steplewski A, Brittingham R, Jimenez SA, Fertala A. Single amino acid substitutions in the C-terminus of collagen II alter its affinity for collagen IX. Biochem Biophys Res Commun. 2005 Sep 30; 335(3):749-55. PMID: 16087158.
      Citations:    
    104. Derk CT, Jimenez SA. Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? Autoimmun Rev. 2006 Jan; 5(1):25-32. PMID: 16338208.
      Citations:    
    105. Gentiletti J, McCloskey LJ, Artlett CM, Peters J, Jimenez SA, Christner PJ. Demonstration of autoimmunity in the tight skin-2 mouse: a model for scleroderma. J Immunol. 2005 Aug 15; 175(4):2418-26. PMID: 16081813.
      Citations:    
    106. Sandorfi N, Louneva N, Hitraya E, Hajnoczky G, Saitta B, Jimenez SA. Inhibition of collagen gene expression in systemic sclerosis dermal fibroblasts by mithramycin. Ann Rheum Dis. 2005 Dec; 64(12):1685-91. PMID: 15901633.
      Citations:    
    107. Colter DC, Piera-Velazquez S, Hawkins DF, Whitecavage MK, Jimenez SA, Stokes DG. Regulation of the human Sox9 promoter by the CCAAT-binding factor. Matrix Biol. 2005 May; 24(3):185-97. PMID: 15908194.
      Citations:    
    108. Taylor RA, Levine JM, Jimenez SA. Case 35-2004: nephrogenic fibrosing dermopathy. N Engl J Med. 2005 Apr 21; 352(16):1723-4; author reply 1723-4. PMID: 15843679.
      Citations:    
    109. Derk CT, Rasheed M, Spiegel JR, Jimenez SA. Increased incidence of carcinoma of the tongue in patients with systemic sclerosis. J Rheumatol. 2005 Apr; 32(4):637-41. PMID: 15801018.
      Citations:    
    110. Sandorfi N, Jimenez SA. Scleroderma fibroblast survival in Aktion. J Invest Dermatol. 2005 Feb; 124(2):viii-xi. PMID: 15675944.
      Citations:    
    111. Jimenez SA, Artlett CM. Microchimerism and systemic sclerosis. Curr Opin Rheumatol. 2005 Jan; 17(1):86-90. PMID: 15604910.
      Citations:    
    112. Markova MS, Zeskand J, McEntee B, Rothstein J, Jimenez SA, Siracusa LD. A role for the androgen receptor in collagen content of the skin. J Invest Dermatol. 2004 Dec; 123(6):1052-6. PMID: 15610513.
      Citations:    
    113. Steplewski A, Ito H, Rucker E, Brittingham RJ, Alabyeva T, Gandhi M, Ko FK, Birk DE, Jimenez SA, Fertala A. Position of single amino acid substitutions in the collagen triple helix determines their effect on structure of collagen fibrils. J Struct Biol. 2004 Dec; 148(3):326-37. PMID: 15522781.
      Citations:    
    114. Christner PJ, Jimenez SA. Animal models of systemic sclerosis: insights into systemic sclerosis pathogenesis and potential therapeutic approaches. Curr Opin Rheumatol. 2004 Nov; 16(6):746-52. PMID: 15577614.
      Citations:    
    115. Levine JM, Taylor RA, Elman LB, Bird SJ, Lavi E, Stolzenberg ED, McGarvey ML, Asbury AK, Jimenez SA. Involvement of skeletal muscle in dialysis-associated systemic fibrosis (nephrogenic fibrosing dermopathy). Muscle Nerve. 2004 Nov; 30(5):569-77. PMID: 15389718.
      Citations:    
    116. Sawaya HH, Jimenez SA, Artlett CM. Quantification of fetal microchimeric cells in clinically affected and unaffected skin of patients with systemic sclerosis. Rheumatology (Oxford). 2004 Aug; 43(8):965-8. PMID: 15199216.
      Citations:    
    117. Heyt GJ, Oh MK, Alemzadeh N, Rivera S, Jimenez SA, Rattan S, Cohen S, Dimarino AJ. Impaired rectoanal inhibitory response in scleroderma (systemic sclerosis): an association with fecal incontinence. Dig Dis Sci. 2004 Jun; 49(6):1040-5. PMID: 15309898.
      Citations:    
    118. Steplewski A, Majsterek I, McAdams E, Rucker E, Brittingham RJ, Ito H, Hirai K, Adachi E, Jimenez SA, Fertala A. Thermostability gradient in the collagen triple helix reveals its multi-domain structure. J Mol Biol. 2004 May 14; 338(5):989-98. PMID: 15111062.
      Citations:    
    119. Barnes KC, Caraballo L, Mu?oz M, Zambelli-Weiner A, Ehrlich E, Burki M, Jimenez S, Mathias RA, Stockton ML, Deindl P, Mendoza L, Hershey GK, Nickel R, Wills-Karp M. A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations. Clin Exp Allergy. 2004 May; 34(5):736-44. PMID: 15144465.
      Citations:    
    120. Coimbra IB, Jimenez SA, Hawkins DF, Piera-Velazquez S, Stokes DG. Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes. Osteoarthritis Cartilage. 2004 Apr; 12(4):336-45. PMID: 15023385.
      Citations:    
    121. Cicchillitti L, Jimenez SA, Sala A, Saitta B. B-Myb acts as a repressor of human COL1A1 collagen gene expression by interacting with Sp1 and CBF factors in scleroderma fibroblasts. Biochem J. 2004 Mar 01; 378(Pt 2):609-16. PMID: 14613485.
      Citations:    
    122. Jimenez SA, Derk CT. Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis. Ann Intern Med. 2004 Jan 06; 140(1):37-50. PMID: 14706971.
      Citations:    
    123. Derk CT, Conway RT, Jimenez SA. Primary B-cell lymphoma of the tongue in a patient with systemic sclerosis. Oral Oncol. 2004 Jan; 40(1):103-6. PMID: 14662423.
      Citations:    
    124. Williams CJ, Jimenez SA. Skeletal dysplasias and the osteoarthritic phenotype. Best Pract Res Clin Rheumatol. 2003 Dec; 17(6):1005-18. PMID: 15123048.
      Citations:    
    125. Derk CT, Sakkas LI, Rasheed M, Artlett C, Jimenez SA. Autoantibodies in patients with systemic sclerosis and cancer: a case-control study. J Rheumatol. 2003 Sep; 30(9):1994-6. PMID: 12966604.
      Citations:    
    126. Louneva N, Saitta B, Herrick DJ, Jimenez SA. Transcriptional inhibition of type I collagen gene expression in scleroderma fibroblasts by the antineoplastic drug ecteinascidin 743. J Biol Chem. 2003 Oct 10; 278(41):40400-7. PMID: 12881530.
      Citations:    
    127. Derk CT, Jimenez SA. Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature. J Rheumatol. 2003 Jul; 30(7):1616-20. PMID: 12858467.
      Citations:    
    128. Atamas SP, Luzina IG, Choi J, Tsymbalyuk N, Carbonetti NH, Singh IS, Trojanowska M, Jimenez SA, White B. Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts. Am J Respir Cell Mol Biol. 2003 Dec; 29(6):743-9. PMID: 12805086.
      Citations:    
    129. Derk CT, Jimenez SA. Systemic sclerosis: current views of its pathogenesis. Autoimmun Rev. 2003 Jun; 2(4):181-91. PMID: 12848944.
      Citations:    
    130. Dodge GR, Jimenez SA. Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes. Osteoarthritis Cartilage. 2003 Jun; 11(6):424-32. PMID: 12801482.
      Citations:    
    131. Cox LA, Ramos RC, Dennis TN, Jimenez SA, Smith JB, Artlett CM. Detection of microchimeric cells in the peripheral blood of nonpregnant women is enhanced by magnetic cell sorting before PCR. Clin Chem. 2003 Feb; 49(2):309-12. PMID: 12560357.
      Citations:    
    132. Jimenez SA, Christner PJ. Murine animal models of systemic sclerosis. Curr Opin Rheumatol. 2002 Nov; 14(6):671-80. PMID: 12410090.
      Citations:    
    133. Zhang P, Jimenez SA, Stokes DG. Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9. J Biol Chem. 2003 Jan 03; 278(1):117-23. PMID: 12399468.
      Citations:    
    134. Arita M, Li SW, Kopen G, Adachi E, Jimenez SA, Fertala A. Skeletal abnormalities and ultrastructural changes of cartilage in transgenic mice expressing a collagen II gene (COL2A1) with a Cys for Arg-alpha1-519 substitution. Osteoarthritis Cartilage. 2002 Oct; 10(10):808-15. PMID: 12359167.
      Citations:    
    135. Artlett CM, Cox LA, Ramos RC, Dennis TN, Fortunato RA, Hummers LK, Jimenez SA, Smith JB. Increased microchimeric CD4+ T lymphocytes in peripheral blood from women with systemic sclerosis. Clin Immunol. 2002 Jun; 103(3 Pt 1):303-8. PMID: 12173305.
      Citations:    
    136. Sakkas LI, Xu B, Artlett CM, Lu S, Jimenez SA, Platsoucas CD. Oligoclonal T cell expansion in the skin of patients with systemic sclerosis. J Immunol. 2002 Apr 01; 168(7):3649-59. PMID: 11907131.
      Citations:    
    137. Artlett CM, Rasheed M, Russo-Stieglitz KE, Sawaya HH, Jimenez SA. Influence of prior pregnancies on disease course and cause of death in systemic sclerosis. Ann Rheum Dis. 2002 Apr; 61(4):346-50. PMID: 11874839.
      Citations:    
    138. Piera-Velazquez S, Jimenez SA, Stokes D. Increased life span of human osteoarthritic chondrocytes by exogenous expression of telomerase. Arthritis Rheum. 2002 Mar; 46(3):683-93. PMID: 11920404.
      Citations:    
    139. Agha B, Rasheed M, Kenyon L, Jimenez SA. Hepatitis C virus infection, inflammatory myopathy, and pulmonary fibrosis: are they related? J Clin Rheumatol. 2002 Feb; 8(1):44-9. PMID: 17039200.
      Citations:    
    140. Fertala A, Sieron AL, Adachi E, Jimenez SA. Collagen II containing a Cys substitution for Arg-alpha1-519: abnormal interactions of the mutated molecules with collagen IX. Biochemistry. 2001 Dec 04; 40(48):14422-8. PMID: 11724554.
      Citations:    
    141. Stokes DG, Liu G, Dharmavaram R, Hawkins D, Piera-Velazquez S, Jimenez SA. Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors. Biochem J. 2001 Dec 01; 360(Pt 2):461-70. PMID: 11716775.
      Citations:    
    142. Jimenez SA, Gaidarova S, Saitta B, Sandorfi N, Herrich DJ, Rosenbloom JC, Kucich U, Abrams WR, Rosenbloom J. Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts. J Clin Invest. 2001 Nov; 108(9):1395-403. PMID: 11696585.
      Citations:    
    143. Estrada LE, Dodge GR, Richardson DW, Farole A, Jimenez SA. Characterization of a biomaterial with cartilage-like properties expressing type X collagen generated in vitro using neonatal porcine articular and growth plate chondrocytes. Osteoarthritis Cartilage. 2001 Feb; 9(2):169-77. PMID: 11237664.
      Citations:    
    144. Saitta B, Gaidarova S, Cicchillitti L, Jimenez SA. CCAAT binding transcription factor binds and regulates human COL1A1 promoter activity in human dermal fibroblasts: demonstration of increased binding in systemic sclerosis fibroblasts. Arthritis Rheum. 2000 Oct; 43(10):2219-29. PMID: 11037881.
      Citations:    
    145. Rider LG, Artlett CM, Foster CB, Ahmed A, Neeman T, Chanock SJ, Jimenez SA, Miller FW. Polymorphisms in the IL-1 receptor antagonist gene VNTR are possible risk factors for juvenile idiopathic inflammatory myopathies. Clin Exp Immunol. 2000 Jul; 121(1):47-52. PMID: 10886238.
      Citations:    
    146. Rosenbloom J, Saitta B, Gaidarova S, Sandorfi N, Rosenbloom JC, Abrams WR, Hamilton AD, Sebti SM, Kucich U, Jimenez SA. Inhibition of type I collagen gene expression in normal and systemic sclerosis fibroblasts by a specific inhibitor of geranylgeranyl transferase I. Arthritis Rheum. 2000 Jul; 43(7):1624-32. PMID: 10902768.
      Citations:    
    147. Artlett CM, Cox LA, Jimenez SA. Detection of cellular microchimerism of male or female origin in systemic sclerosis patients by polymerase chain reaction analysis of HLA-Cw antigens. Arthritis Rheum. 2000 May; 43(5):1062-7. PMID: 10817560.
      Citations:    
    148. Kipnes JR, Xu L, Han F, Rallapalli R, Jimenez S, Hall DJ, Tuan RS, Li Y. Molecular cloning and expression patterns of mouse cartilage oligomeric matrix protein gene. Osteoarthritis Cartilage. 2000 May; 8(3):236-9. PMID: 10806052.
      Citations:    
    149. Shapiro M, Jimenez S, Werth VP. Pemphigus vulgaris induced by D-penicillamine therapy in a patient with systemic sclerosis. J Am Acad Dermatol. 2000 Feb; 42(2 Pt 1):297-9. PMID: 10642693.
      Citations:    
    150. Medsger TA, Silman AJ, Steen VD, Black CM, Akesson A, Bacon PA, Harris CA, Jablonska S, Jayson MI, Jimenez SA, Krieg T, Leroy EC, Maddison PJ, Russell ML, Schachter RK, Wollheim FA, Zacharaie H. A disease severity scale for systemic sclerosis: development and testing. J Rheumatol. 1999 Oct; 26(10):2159-67. PMID: 10529133.
      Citations:    
    151. Artlett CM, Smith JB, Jimenez SA. New perspectives on the etiology of systemic sclerosis. Mol Med Today. 1999 Feb; 5(2):74-8. PMID: 10200948.
      Citations:    
    152. Jimenez SA, Saitta B. Alterations in the regulation of expression of the alpha 1(I) collagen gene (COL1A1) in systemic sclerosis (scleroderma). Springer Semin Immunopathol. 1999; 21(4):397-414. PMID: 10945033.
      Citations:    
    153. Siracusa LD, McGrath R, Fisher JK, Jimenez SA. The mouse tight skin (Tsk) phenotype is not dependent on the presence of mature T and B lymphocytes. Mamm Genome. 1998 Nov; 9(11):907-9. PMID: 9799844.
      Citations:    
    154. Dodge GR, Hawkins D, Boesler E, Sakai L, Jimenez SA. Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts. Osteoarthritis Cartilage. 1998 Nov; 6(6):435-40. PMID: 10343777.
      Citations:    
    155. Artlett CM, Chen SJ, Varga J, Jimenez SA. Modulation of basal expression of the human alpha1(I) procollagen gene (COL1A1) by tandem NF-1/Sp1 promoter elements in normal human dermal fibroblasts. Matrix Biol. 1998 Oct; 17(6):425-34. PMID: 9840444.
      Citations:    
    156. Chen SJ, Artlett CM, Jimenez SA, Varga J. Modulation of human alpha1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro. Gene. 1998 Jul 17; 215(1):101-10. PMID: 9666093.
      Citations:    
    157. V?rai G, Earle L, Jimenez SA, Steiner RM, Varga J. A pilot study of intermittent intravenous cyclophosphamide for the treatment of systemic sclerosis associated lung disease. J Rheumatol. 1998 Jul; 25(7):1325-9. PMID: 9676764.
      Citations:    
    158. Diaz A, Chepenik KP, Korn JH, Reginato AM, Jimenez SA. Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts. Exp Cell Res. 1998 May 25; 241(1):222-9. PMID: 9633531.
      Citations:    
    159. Artlett CM, Smith JB, Jimenez SA. Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis. N Engl J Med. 1998 Apr 23; 338(17):1186-91. PMID: 9554859.
      Citations:    
    160. Wigley FM, Korn JH, Csuka ME, Medsger TA, Rothfield NF, Ellman M, Martin R, Collier DH, Weinstein A, Furst DE, Jimenez SA, Mayes MD, Merkel PA, Gruber B, Kaufman L, Varga J, Bell P, Kern J, Marrott P, White B, Simms RW, Phillips AC, Seibold JR. Oral iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis: a multicenter, placebo-controlled, double-blind study. Arthritis Rheum. 1998 Apr; 41(4):670-7. PMID: 9550476.
      Citations:    
    161. Kielty CM, Raghunath M, Siracusa LD, Sherratt MJ, Peters R, Shuttleworth CA, Jimenez SA. The Tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils. J Cell Biol. 1998 Mar 09; 140(5):1159-66. PMID: 9490728.
      Citations:    
    162. Reginato AM, Bashey RI, Rosselot G, Leach RM, Gay CV, Jimenez SA. Type X collagen biosynthesis and expression in avian tibial dyschondroplasia. Osteoarthritis Cartilage. 1998 Mar; 6(2):125-36. PMID: 9692067.
      Citations:    
    163. Dodge GR, Diaz A, Sanz-Rodriguez C, Reginato AM, Jimenez SA. Effects of interferon-gamma and tumor necrosis factor alpha on the expression of the genes encoding aggrecan, biglycan, and decorin core proteins in cultured human chondrocytes. Arthritis Rheum. 1998 Feb; 41(2):274-83. PMID: 9485085.
      Citations:    
    164. Wooley PH, Sud S, Langendorfer A, Calkins C, Christner PJ, Peters J, Jimenez SA. T cells infiltrating the skin of Tsk2 scleroderma-like mice exhibit T cell receptor bias. Autoimmunity. 1998; 27(2):91-8. PMID: 9583740.
      Citations:    
    165. Dharmavaram RM, Liu G, Mowers SD, Jimenez SA. Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation. J Biol Chem. 1997 Oct 24; 272(43):26918-25. PMID: 9341126.
      Citations:    
    166. Jimenez SA, Ala-Kokko L, Prockop DJ, Merryman CF, Shepard N, Dodge GR. Characterization of human type II procollagen and collagen-specific antibodies and their application to the study of human type II collagen processing and ultrastructure. Matrix Biol. 1997 Apr; 16(1):29-39. PMID: 9181552.
      Citations:    
    167. Caraballo L, Puerta L, Jimenez S, Martinez B, Mercado D, Avjiouglu A, Marsh D. Cloning and IgE binding of a recombinant allergen from the mite Blomia tropicalis, homologous with fatty acid-binding proteins. Int Arch Allergy Immunol. 1997 Apr; 112(4):341-7. PMID: 9104789.
      Citations:    
    168. Artlett CM, Welsh KI, Black CM, Jimenez SA. Fetal-maternal HLA compatibility confers susceptibility to systemic sclerosis. Immunogenetics. 1997; 47(1):17-22. PMID: 9382916.
      Citations:    
    169. Hitraya EG, Jimenez SA, Ludwicka A, Silver RM, Varga J. Increased activity of the alpha 1(I) procollagen promoter in skin fibroblasts from patients with chronic eosinophilia-myalgia syndrome. Int J Biochem Cell Biol. 1997 Jan; 29(1):135-41. PMID: 9076948.
      Citations:    
    170. Jimenez SA, Hitraya E, Varga J. Pathogenesis of scleroderma. Collagen. Rheum Dis Clin North Am. 1996 Nov; 22(4):647-74. PMID: 8923589.
      Citations:    
    171. Mori K, Hatamochi A, Ueki H, Olsen A, Jimenez SA. The transcription of human alpha 1(I) procollagen gene (COL1A1) is suppressed by tumour necrosis factor-alpha through proximal short promoter elements: evidence for suppression mechanisms mediated by two nuclear-factorbinding sites. Biochem J. 1996 Nov 01; 319 ( Pt 3):811-6. PMID: 8920984.
      Citations:    
    172. Christner PJ, Siracusa LD, Hawkins DF, McGrath R, Betz JK, Ball ST, Jimenez SA, Peters J. A high-resolution linkage map of the tight skin 2 (Tsk2) locus: a mouse model for scleroderma (SSc) and other cutaneous fibrotic diseases. Mamm Genome. 1996 Aug; 7(8):610-2. PMID: 8678985.
      Citations:    
    173. Wechsler RJ, Steiner RM, Spirn PW, Rubin S, Salazar AM, Shah R, Russell K, Jimenez S, Varga J. The relationship of thoracic lymphadenopathy to pulmonary interstitial disease in diffuse and limited systemic sclerosis: CT findings. AJR Am J Roentgenol. 1996 Jul; 167(1):101-4. PMID: 8659350.
      Citations:    
    174. Christner P, Yankowski RL, Benditt M, Jimenez SA. Alteration in the conformational stability of collagen caused by the incorporation of the lysine analogue S-2-aminoethylcysteine. Biochim Biophys Acta. 1996 May 02; 1294(1):37-47. PMID: 8639712.
      Citations:    
    175. Kane GC, Varga J, Conant EF, Spirn PW, Jimenez S, Fish JE. Lung involvement in systemic sclerosis (scleroderma): relation to classification based on extent of skin involvement or autoantibody status. Respir Med. 1996 Apr; 90(4):223-30. PMID: 8736656.
      Citations:    
    176. Siracusa LD, McGrath R, Ma Q, Moskow JJ, Manne J, Christner PJ, Buchberg AM, Jimenez SA. A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation. Genome Res. 1996 Apr; 6(4):300-13. PMID: 8723723.
      Citations:    
    177. Kahari L, Jimenez SA. Increased expression of transforming growth factor-beta1, fibronectin, and Types I, III, and VI collagen genes in fascial fibroblasts from patients with diffuse fasciitis with eosinophilia. J Rheumatol. 1996 Mar; 23(3):482-6. PMID: 8832987.
      Citations:    
    178. Kr?ling BM, Juhasz I, Freundlich B, Maul GG, Jimenez SA. Transplantation of systemic sclerosis (SSc) skin grafts into severe combined immunodeficient mice: increased presence of SSc leukocytes in SSc skin grafts and autoantibody production following autologous leukocyte transfer. Pathobiology. 1996; 64(2):99-114. PMID: 8888275.
      Citations:    
    179. Batuman OA, Ferrero A, Cupp C, Jimenez SA, Khalili K. Differential regulation of transforming growth factor beta-1 gene expression by glucocorticoids in human T and glial cells. J Immunol. 1995 Nov 01; 155(9):4397-405. PMID: 7594600.
      Citations:    
    180. Dodge GR, Boesler EW, Jimenez SA. Expression of the basement membrane heparan sulfate proteoglycan (perlecan) in human synovium and in cultured human synovial cells. Lab Invest. 1995 Nov; 73(5):649-57. PMID: 7474938.
      Citations:    
    181. Li L, Artlett CM, Jimenez SA, Hall DJ, Varga J. Positive regulation of human alpha 1 (I) collagen promoter activity by transcription factor Sp1. Gene. 1995 Oct 27; 164(2):229-34. PMID: 7590335.
      Citations:    
    182. Heimer R, Bashey RI, Kyle J, Jimenez SA. TGF-beta modulates the synthesis of proteoglycans by myocardial fibroblasts in culture. J Mol Cell Cardiol. 1995 Oct; 27(10):2191-8. PMID: 8576935.
      Citations:    
    183. Hitraya EG, Tan EM, Rudnicka L, Jimenez SA. Expression of extracellular matrix genes in adult human dermal microvascular endothelial cells and their regulation by heparin and endothelial cell mitogens. Lab Invest. 1995 Sep; 73(3):393-402. PMID: 7564272.
      Citations:    
    184. Kaufman LD, Varga J, Gomez-Reino JJ, Jimenez S, Targoff IN. Autoantibodies in sera from patients with L-tryptophan-associated eosinophilia-myalgia syndrome. Demonstration of unique antigen-antibody specificities. Clin Immunol Immunopathol. 1995 Aug; 76(2):115-9. PMID: 7542184.
      Citations:    
    185. Cox D, Earle L, Jimenez SA, Leiferman KM, Gleich GJ, Varga J. Elevated levels of eosinophil major basic protein in the sera of patients with systemic sclerosis. Arthritis Rheum. 1995 Jul; 38(7):939-45. PMID: 7612043.
      Citations:    
    186. Hitraya EG, Varga J, Jimenez SA. Heat shock of human synovial and dermal fibroblasts induces delayed up-regulation of collagenase-gene expression. Biochem J. 1995 Jun 15; 308 ( Pt 3):743-7. PMID: 8948427.
      Citations:    
    187. Reginato AM, Sanz-Rodriguez C, Jimenez SA. Biosynthesis and characterization of type X collagen in human fetal epiphyseal growth plate cartilage. Osteoarthritis Cartilage. 1995 Jun; 3(2):105-16. PMID: 7584316.
      Citations:    
    188. Marcos JC, Arturi AS, Babini C, Jimenez S, Knowlton R, Reginato AJ. Familial Hydroxyapatite Chondrocalcinosis with Spondyloepiphyseal Dysplasia: Clinical Course and Absence of Genetic Linkage to the Type II Procollagen Gene. J Clin Rheumatol. 1995 Jun; 1(3):171-8. PMID: 19077971.
      Citations:    
    189. Cox D, Conant E, Earle L, Newman J, Kahaleh B, Jimenez S, Varga J. Sarcoidosis in systemic sclerosis: report of 7 cases. J Rheumatol. 1995 May; 22(5):881-5. PMID: 8587076.
      Citations:    
    190. Williams CJ, Jimenez SA. Heritable diseases of cartilage caused by mutations in collagen genes. J Rheumatol Suppl. 1995 Feb; 43:28-33. PMID: 7752129.
      Citations:    
    191. Van de Water J, Jimenez SA, Gershwin ME. Animal models of scleroderma: contrasts and comparisons. Int Rev Immunol. 1995; 12(2-4):201-16. PMID: 7544386.
      Citations:    
    192. Varga J, Jimenez SA. Modulation of collagen gene expression: its relation to fibrosis in systemic sclerosis and other disorders. Ann Intern Med. 1995 Jan 01; 122(1):60-2. PMID: 7985897.
      Citations:    
    193. Rudnicka L, Diaz A, Varga J, Christiano A, Uitto J, Jimenez SA. Use of spontaneously mutated human DNA as competitive internal standard for nucleic acid quantification by reverse transcription-polymerase chain reaction (RT-PCR). Arch Immunol Ther Exp (Warsz). 1995; 43(2):111-5. PMID: 8744725.
      Citations:    
    194. Jimenez SA, Diaz A, Khalili K. Retroviruses and the pathogenesis of systemic sclerosis. Int Rev Immunol. 1995; 12(2-4):159-75. PMID: 7650419.
      Citations:    
    195. Kr?ling BM, Maul GG, Jimenez SA. Mononuclear cellular infiltrates in clinically involved skin from patients with systemic sclerosis of recent onset predominantly consist of monocytes/macrophages. Pathobiology. 1995; 63(1):48-56. PMID: 7546275.
      Citations:    
    196. Jimenez SA, Dharmavaram RM. Genetic aspects of familial osteoarthritis. Ann Rheum Dis. 1994 Dec; 53(12):789-97. PMID: 7864685.
      Citations:    
    197. Goldstein C, Liaw P, Jimenez SA, Buchberg AM, Siracusa LD. Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome. Mamm Genome. 1994 Nov; 5(11):696-700. PMID: 7873879.
      Citations:    
    198. Kr?ling BM, Jimenez SA, Sorger T, Maul GG. Isolation and characterization of microvascular endothelial cells from the adult human dermis and from skin biopsies of patients with systemic sclerosis. Lab Invest. 1994 Nov; 71(5):745-54. PMID: 7967526.
      Citations:    
    199. Reginato AM, Iozzo RV, Jimenez SA. Formation of nodular structures resembling mature articular cartilage in long-term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate. Arthritis Rheum. 1994 Sep; 37(9):1338-49. PMID: 7945499.
      Citations:    
    200. Philips N, Bashey RI, Jimenez SA. Collagen and fibronectin expression in cardiac fibroblasts from hypertensive rats. Cardiovasc Res. 1994 Sep; 28(9):1342-7. PMID: 7954643.
      Citations:    
    201. Chepenik KP, Diaz A, Jimenez SA. Epidermal growth factor coordinately regulates the expression of prostaglandin G/H synthase and cytosolic phospholipase A2 genes in embryonic mouse cells. J Biol Chem. 1994 Aug 26; 269(34):21786-92. PMID: 8063822.
      Citations:    
    202. Reginato AJ, Passano GM, Neumann G, Falasca GF, Diaz-Valdez M, Jimenez SA, Williams CJ. Familial spondyloepiphyseal dysplasia tarda, brachydactyly, and precocious osteoarthritis associated with an arginine 75-->cysteine mutation in the procollagen type II gene in a kindred of Chiloe Islanders. I. Clinical, radiographic, and pathologic findings. Arthritis Rheum. 1994 Jul; 37(7):1078-86. PMID: 8024616.
      Citations:    
    203. Troshinsky MB, Kane GC, Varga J, Cater JR, Fish JE, Jimenez SA, Castell DO. Pulmonary function and gastroesophageal reflux in systemic sclerosis. Ann Intern Med. 1994 Jul 01; 121(1):6-10. PMID: 8198350.
      Citations:    
    204. Jimenez SA, Christner P. Animal models of systemic sclerosis. Clin Dermatol. 1994 Jul-Sep; 12(3):425-36. PMID: 7954200.
      Citations:    
    205. Jimenez SA, Varga J, Olsen A, Li L, Diaz A, Herhal J, Koch J. Functional analysis of human alpha 1(I) procollagen gene promoter. Differential activity in collagen-producing and -nonproducing cells and response to transforming growth factor beta 1. J Biol Chem. 1994 Apr 29; 269(17):12684-91. PMID: 8175678.
      Citations:    
    206. Rudnicka L, Varga J, Christiano AM, Iozzo RV, Jimenez SA, Uitto J. Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. J Clin Invest. 1994 Apr; 93(4):1709-15. PMID: 7512991.
      Citations:    
    207. Jimenez SA. New insights into the pathogenesis of interstitial pulmonary fibrosis. Thorax. 1994 Mar; 49(3):193-5. PMID: 8202871.
      Citations:    
    208. Dharmavaram RM, Elberson MA, Peng M, Kirson LA, Kelley TE, Jimenez SA. Identification of a mutation in type X collagen in a family with Schmid metaphyseal chondrodysplasia. Hum Mol Genet. 1994 Mar; 3(3):507-9. PMID: 8012364.
      Citations:    
    209. Varga J, Li L, Mauviel A, Jeffrey J, Jimenez SA. L-Tryptophan in supraphysiologic concentrations stimulates collagenase gene expression in human skin fibroblasts. Lab Invest. 1994 Feb; 70(2):183-91. PMID: 8139260.
      Citations:    
    210. Wigley FM, Wise RA, Seibold JR, McCloskey DA, Kujala G, Medsger TA, Steen VD, Varga J, Jimenez S, Mayes M, Clements PJ, Weiner SR, Porter J, Ellman M, Wise C, Kaufman LD, Williams J, Dole W. Intravenous iloprost infusion in patients with Raynaud phenomenon secondary to systemic sclerosis. A multicenter, placebo-controlled, double-blind study. Ann Intern Med. 1994 Feb 01; 120(3):199-206. PMID: 7506013.
      Citations:    
    211. Cho MM, Jimenez SA, Johnson BA, Harlow LA, Burrows JC, Koch AE. In vitro cytokine modulation of intercellular adhesion molecule-1 expression on systemic sclerosis dermal fibroblasts. Pathobiology. 1994; 62(2):73-81. PMID: 7945915.
      Citations:    
    212. Oehlmann R, Summerville GP, Yeh G, Weaver EJ, Jimenez SA, Knowlton RG. Genetic linkage mapping of multiple epiphyseal dysplasia to the pericentromeric region of chromosome 19. Am J Hum Genet. 1994 Jan; 54(1):3-10. PMID: 8279467.
      Citations:    
    213. Varga J, Jimenez SA. Chemical exposure-induced cutaneous fibrosis. Lessons from 'experiments of nature'. Arch Dermatol. 1994 Jan; 130(1):97-100. PMID: 8285747.
      Citations:    
    214. Reginato AM, Tuan RS, Ono T, Jimenez SA, Jacenko O. Effects of calcium deficiency on chondrocyte hypertrophy and type X collagen expression in chick embryonic sternum. Dev Dyn. 1993 Dec; 198(4):284-95. PMID: 8130376.
      Citations:    
    215. Williams CJ, Considine EL, Knowlton RG, Reginato A, Neumann G, Harrison D, Buxton P, Jimenez S, Prockop DJ. Spondyloepiphyseal dysplasia and precocious osteoarthritis in a family with an Arg75-->Cys mutation in the procollagen type II gene (COL2A1). Hum Genet. 1993 Nov; 92(5):499-505. PMID: 8244341.
      Citations:    
    216. Reginato AM, Sanz-Rodriguez C, Diaz A, Dharmavaram RM, Jimenez SA. Transcriptional modulation of cartilage-specific collagen gene expression by interferon gamma and tumour necrosis factor alpha in cultured human chondrocytes. Biochem J. 1993 Sep 15; 294 ( Pt 3):761-9. PMID: 8379931.
      Citations:    
    217. Bashey RI, Sampson PM, Jimenez SA, Heimer R. Glycosaminoglycans and chondroitin/dermatan sulfate proteoglycans in the myocardium of a non-human primate. Matrix. 1993 Sep; 13(5):363-71. PMID: 8246832.
      Citations:    
    218. Siracusa LD, Christner P, McGrath R, Mowers SD, Nelson KK, Jimenez SA. The tight skin (Tsk) mutation in the mouse, a model for human fibrotic diseases, is tightly linked to the beta 2-microglobulin (B2m) gene on chromosome 2. Genomics. 1993 Sep; 17(3):748-51. PMID: 7902327.
      Citations:    
    219. Williams CJ, Jimenez SA. Heredity, genes and osteoarthritis. Rheum Dis Clin North Am. 1993 Aug; 19(3):523-43. PMID: 8210573.
      Citations:    
    220. Varga J, Li L, Jimenez SA. Increased type I collagen gene expression in L-tryptophan associated eosinophilia-myalgia syndrome skin fibroblasts. J Rheumatol. 1993 Aug; 20(8):1303-8. PMID: 8230009.
      Citations:    
    221. Miller LS, Liu JB, Klenn PJ, Holahan MP, Varga J, Feld RI, Troshinsky M, Jimenez SA, Castell DO, Goldberg BB. Endoluminal ultrasonography of the distal esophagus in systemic sclerosis. Gastroenterology. 1993 Jul; 105(1):31-9. PMID: 8514059.
      Citations:    
    222. Bashey RI, Philips N, Insinga F, Jimenez SA. Increased collagen synthesis and increased content of type VI collagen in myocardium of tight skin mice. Cardiovasc Res. 1993 Jun; 27(6):1061-5. PMID: 8221765.
      Citations:    
    223. Yarze JC, Varga J, Stampfl D, Castell DO, Jimenez SA. Esophageal function in systemic sclerosis: a prospective evaluation of motility and acid reflux in 36 patients. Am J Gastroenterol. 1993 Jun; 88(6):870-6. PMID: 8503383.
      Citations:    
    224. Bocchieri MH, Christner PJ, Henriksen PD, Jimenez SA. Immunological characterization of (tight skin/NZB)F1 hybrid mice with connective tissue and autoimmune features resembling human systemic sclerosis. J Autoimmun. 1993 Jun; 6(3):337-51. PMID: 8397715.
      Citations:    
    225. Diaz A, Munoz E, Johnston R, Korn JH, Jimenez SA. Regulation of human lung fibroblast alpha 1(I) procollagen gene expression by tumor necrosis factor alpha, interleukin-1 beta, and prostaglandin E2. J Biol Chem. 1993 May 15; 268(14):10364-71. PMID: 7683676.
      Citations:    
    226. Dharmavaram RM, Baldwin CT, Reginato AM, Jimenez SA. Amplification of cDNAs for human cartilage-specific types II, IX and XI collagens from chondrocytes and Epstein-Barr virus-transformed lymphocytes. Matrix. 1993 Mar; 13(2):125-33. PMID: 8388073.
      Citations:    
    227. Reitamo S, Remitz A, Varga J, Ceska M, Effenberger F, Jimenez S, Uitto J. Demonstration of interleukin 8 and autoantibodies to interleukin 8 in the serum of patients with systemic sclerosis and related disorders. Arch Dermatol. 1993 Feb; 129(2):189-93. PMID: 8434976.
      Citations:    
    228. Weaver EJ, Summerville GP, Yeh G, Hervada-Page M, Oehlmann R, Rothman R, Jimenez SA, Knowlton RG. Exclusion of type II and type VI procollagen gene mutations in a five-generation family with multiple epiphyseal dysplasia. Am J Med Genet. 1993 Feb 01; 45(3):345-52. PMID: 8094597.
      Citations:    
    229. Varga J, Jimenez SA, Uitto J. L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis. J Invest Dermatol. 1993 Jan; 100(1):97S-105S. PMID: 8423409.
      Citations:    
    230. Jimenez SA, Batuman O. Immunopathogenesis of systemic sclerosis: possible role of retroviruses. Autoimmunity. 1993; 16(3):225-33. PMID: 8003618.
      Citations:    
    231. Varga J, Matsuoka LY, Hashimoto K, Di Leonardo M, Jimenez SA. Papular mucinosis (scleromyxoedema) complicating diffuse systemic sclerosis: clinical features and electron microscope observations. Br J Rheumatol. 1992 Nov; 31(11):779-82. PMID: 1450804.
      Citations:    
    232. Taylor JP, Cupp C, Diaz A, Chowdhury M, Khalili K, Jimenez SA, Amini S. Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Proc Natl Acad Sci U S A. 1992 Oct 15; 89(20):9617-21. PMID: 1409674.
      Citations:    
    233. Freundlich B, Jimenez SA, Steen VD, Medsger TA, Szkolnicki M, Jaffe HS. Treatment of systemic sclerosis with recombinant interferon-gamma. A phase I/II clinical trial. Arthritis Rheum. 1992 Oct; 35(10):1134-42. PMID: 1418004.
      Citations:    
    234. Dharmavaram RM, Peng M, Strawbridge RR, Jimenez SA. Polymerase chain reaction--amplification of the coding sequence of the type X collagen gene from genomic DNA and identification of a polymorphism that changes Gly to Arg at position 545 by single-strand conformation polymorphism analysis. Biochem Biophys Res Commun. 1992 Aug 31; 187(1):420-4. PMID: 1520329.
      Citations:    
    235. Bashey RI, Donnelly M, Insinga F, Jimenez SA. Growth properties and biochemical characterization of collagens synthesized by adult rat heart fibroblasts in culture. J Mol Cell Cardiol. 1992 Jul; 24(7):691-700. PMID: 1404409.
      Citations:    
    236. Diaz A, Reginato AM, Jimenez SA. Alternative splicing of human prostaglandin G/H synthase mRNA and evidence of differential regulation of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha. J Biol Chem. 1992 May 25; 267(15):10816-22. PMID: 1587858.
      Citations:    
    237. Bashey RI, Martinez-Hernandez A, Jimenez SA. Isolation, characterization, and localization of cardiac collagen type VI. Associations with other extracellular matrix components. Circ Res. 1992 May; 70(5):1006-17. PMID: 1568294.
      Citations:    
    238. Uitto J, Varga J, Peltonen J, Jimenez SA. Eosinophilia-myalgia syndrome. Int J Dermatol. 1992 Apr; 31(4):223-8. PMID: 1634285.
      Citations:    
    239. Sollberg S, Peltonen J, Uitto J, Jimenez SA. Elevated expression of beta 1 and beta 2 integrins, intercellular adhesion molecule 1, and endothelial leukocyte adhesion molecule 1 in the skin of patients with systemic sclerosis of recent onset. Arthritis Rheum. 1992 Mar; 35(3):290-8. PMID: 1371389.
      Citations:    
    240. Rook AH, Freundlich B, Jegasothy BV, Perez MI, Barr WG, Jimenez SA, Rietschel RL, Wintroub B, Kahaleh MB, Varga J, et al. Treatment of systemic sclerosis with extracorporeal photochemotherapy. Results of a multicenter trial. Arch Dermatol. 1992 Mar; 128(3):337-46. PMID: 1550365.
      Citations:    
    241. Varga J, Uitto J, Jimenez SA. The cause and pathogenesis of the eosinophilia-myalgia syndrome. Ann Intern Med. 1992 Jan 15; 116(2):140-7. PMID: 1727618.
      Citations:    
    242. Varga J, Maul GG, Jimenez SA. Autoantibodies to nuclear lamin C in the eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Arthritis Rheum. 1992 Jan; 35(1):106-9. PMID: 1290474.
      Citations:    
    243. Jimenez SA, Varga J. The eosinophilia-myalgia syndrome and eosinophilic fasciitis. Curr Opin Rheumatol. 1991 Dec; 3(6):986-94. PMID: 1772754.
      Citations:    
    244. AyanlarBatuman O, Ferrero AP, Diaz A, Jimenez SA. Regulation of transforming growth factor-beta 1 gene expression by glucocorticoids in normal human T lymphocytes. J Clin Invest. 1991 Nov; 88(5):1574-80. PMID: 1939646.
      Citations:    
    245. Caraballo L, Marrugo J, Jimenez S, Angelini G, Ferrara GB. Frequency of DPB1*0401 is significantly decreased in patients with allergic asthma in a mulatto population. Hum Immunol. 1991 Nov; 32(3):157-61. PMID: 1774196.
      Citations:    
    246. Jimenez SA, Sigal SH. A 15-year prospective study of treatment of rapidly progressive systemic sclerosis with D-penicillamine [see comment]. J Rheumatol. 1991 Oct; 18(10):1496-503. PMID: 1765974.
      Citations:    
    247. Ala-Kokko L, Hyland J, Smith C, Kivirikko KI, Jimenez SA, Prockop DJ. Expression of a human cartilage procollagen gene (COL2A1) in mouse 3T3 cells. J Biol Chem. 1991 Aug 05; 266(22):14175-8. PMID: 1860834.
      Citations:    
    248. Ahmad NN, Ala-Kokko L, Knowlton RG, Jimenez SA, Weaver EJ, Maguire JI, Tasman W, Prockop DJ. Stop codon in the procollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy). Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6624-7. PMID: 1677770.
      Citations:    
    249. Matsuoka LY, Dannenberg MJ, Wortsman J, Hollis BW, Jimenez SA, Varga J. Cutaneous vitamin D3 formation in progressive systemic sclerosis. J Rheumatol. 1991 Aug; 18(8):1196-8. PMID: 1658323.
      Citations:    
    250. Varga J, Haustein UF, Creech RH, Dwyer JP, Jimenez SA. Exaggerated radiation-induced fibrosis in patients with systemic sclerosis. JAMA. 1991 Jun 26; 265(24):3292-5. PMID: 2046111.
      Citations:    
    251. Bocchieri MH, Henriksen PD, Kasturi KN, Muryoi T, Bona CA, Jimenez SA. Evidence for autoimmunity in the tight skin mouse model of systemic sclerosis. Arthritis Rheum. 1991 May; 34(5):599-605. PMID: 1851010.
      Citations:    
    252. Bashey RI, Iannotti JP, Rao VH, Reginato AM, Jimenez SA. Comparison of morphological and biochemical characteristics of cultured chondrocytes isolated from proliferative and hypertrophic zones of bovine growth plate cartilage. Differentiation. 1991 Apr; 46(3):199-207. PMID: 1916066.
      Citations:    
    253. Constantinou CD, Jimenez SA. Structure of cDNAs encoding the triple-helical domain of murine alpha 2 (VI) collagen chain and comparison to human and chick homologues. Use of polymerase chain reaction and partially degenerate oligonucleotide for generation of novel cDNA clones. Matrix. 1991 Feb; 11(1):1-9. PMID: 1709252.
      Citations:    
    254. Varga J, Griffin R, Newman JH, Jimenez SA. Eosinophilic fasciitis is clinically distinguishable from the eosinophilia-myalgia syndrome and is not associated with L-tryptophan use. J Rheumatol. 1991 Feb; 18(2):259-63. PMID: 2023221.
      Citations:    
    255. Jimenez SA. Molecular biological approaches to the study of heritable osteoarthritis. J Rheumatol Suppl. 1991 Feb; 27:7-9. PMID: 1674006.
      Citations:    
    256. Reginato AM, Jimenez SA. Biochemical characterization of the native tissue form of type X collagen from embryonic chick sternal cartilage and identification of a chymotrypsin-sensitive site within its triple-helical domain. Biochem J. 1991 Jan 15; 273(Pt 2):333-8. PMID: 1991034.
      Citations:    
    257. Peltonen J, Varga J, Sollberg S, Uitto J, Jimenez SA. Elevated expression of the genes for transforming growth factor-beta 1 and type VI collagen in diffuse fasciitis associated with the eosinophilia-myalgia syndrome. J Invest Dermatol. 1991 Jan; 96(1):20-5. PMID: 1702819.
      Citations:    
    258. Jimenez SA. The eosinophilia-myalgia syndrome and eosinophilic fasciitis. Curr Opin Rheumatol. 1990 Dec; 2(6):960-6. PMID: 2083164.
      Citations:    
    259. Peltonen J, K?h?ri L, Uitto J, Jimenez SA. Increased expression of type VI collagen genes in systemic sclerosis. Arthritis Rheum. 1990 Dec; 33(12):1829-35. PMID: 2261003.
      Citations:    
    260. Varga J, Olsen A, Herhal J, Constantine G, Rosenbloom J, Jimenez SA. Interferon-gamma reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor-beta in normal human fibroblasts. Eur J Clin Invest. 1990 Oct; 20(5):487-93. PMID: 2124978.
      Citations:    
    261. Varga J, Jimenez SA. Augmentation mammoplasty and scleroderma. Is there an association? Arch Dermatol. 1990 Sep; 126(9):1220-2. PMID: 2396840.
      Citations:    
    262. Jimenez SA, Varga J. The eosinophilia-myalgia syndrome. West J Med. 1990 Sep; 153(3):322-3. PMID: 2219901.
      Citations:    
    263. Varga J, Heiman-Patterson TD, Emery DL, Griffin R, Lally EV, Uitto JJ, Jimenez SA. Clinical spectrum of the systemic manifestations of the eosinophilia-myalgia syndrome. Semin Arthritis Rheum. 1990 Jun; 19(6):313-28. PMID: 2164712.
      Citations:    
    264. Lally EV, Jimenez SA. Erectile failure in systemic sclerosis. N Engl J Med. 1990 May 10; 322(19):1398-9. PMID: 2325743.
      Citations:    
    265. Fam AG, Schumacher HR, Clayburne G, Villanueva T, Baker D, Jimenez SA. Effect of joint motion on experimental calcium pyrophosphate dihydrate crystal induced arthritis. J Rheumatol. 1990 May; 17(5):644-55. PMID: 2162961.
      Citations:    
    266. Uitto J, Jimenez S. Fibrotic skin diseases. Clinical presentations, etiologic considerations, and treatment options. Arch Dermatol. 1990 May; 126(5):661-4. PMID: 2185697.
      Citations:    
    267. Varga J, Peltonen J, Uitto J, Jimenez S. Development of diffuse fasciitis with eosinophilia during L-tryptophan treatment: demonstration of elevated type I collagen gene expression in affected tissues. A clinicopathologic study of four patients. Ann Intern Med. 1990 Mar 01; 112(5):344-51. PMID: 2306063.
      Citations:    
    268. Peltonen J, K?h?ri L, Jaakkola S, K?h?ri VM, Varga J, Uitto J, Jimenez SA. Evaluation of transforming growth factor beta and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization. J Invest Dermatol. 1990 Mar; 94(3):365-71. PMID: 2307855.
      Citations:    
    269. Knowlton RG, Katzenstein PL, Moskowitz RW, Weaver EJ, Malemud CJ, Pathria MN, Jimenez SA, Prockop DJ. Genetic linkage of a polymorphism in the type II procollagen gene (COL2A1) to primary osteoarthritis associated with mild chondrodysplasia. N Engl J Med. 1990 Feb 22; 322(8):526-30. PMID: 2300123.
      Citations:    
    270. Bocchieri MH, Jimenez SA. Animal models of fibrosis. Rheum Dis Clin North Am. 1990 Feb; 16(1):153-67. PMID: 2406805.
      Citations:    
    271. Jimenez SA. Other fibrosing syndromes. Curr Opin Rheumatol. 1989 Dec; 1(4):516-22. PMID: 2702055.
      Citations:    
    272. Knowlton RG, Weaver EJ, Struyk AF, Knobloch WH, King RA, Norris K, Shamban A, Uitto J, Jimenez SA, Prockop DJ. Genetic linkage analysis of hereditary arthro-ophthalmopathy (Stickler syndrome) and the type II procollagen gene. Am J Hum Genet. 1989 Nov; 45(5):681-8. PMID: 2573273.
      Citations:    
    273. Maul GG, Jimenez SA, Riggs E, Ziemnicka-Kotula D. Determination of an epitope of the diffuse systemic sclerosis marker antigen DNA topoisomerase I: sequence similarity with retroviral p30gag protein suggests a possible cause for autoimmunity in systemic sclerosis. Proc Natl Acad Sci U S A. 1989 Nov; 86(21):8492-6. PMID: 2479024.
      Citations:    
    274. Sarra-Carbonell S, Jimenez SA. Ehlers-Danlos syndrome associated with acute pancreatitis. J Rheumatol. 1989 Oct; 16(10):1390-4. PMID: 2810267.
      Citations:    
    275. Varga J, Schumacher HR, Jimenez SA. Systemic sclerosis after augmentation mammoplasty with silicone implants. Ann Intern Med. 1989 Sep 01; 111(5):377-83. PMID: 2669593.
      Citations:    
    276. Baldwin CT, Reginato AM, Smith C, Jimenez SA, Prockop DJ. Structure of cDNA clones coding for human type II procollagen. The alpha 1(II) chain is more similar to the alpha 1(I) chain than two other alpha chains of fibrillar collagens. Biochem J. 1989 Sep 01; 262(2):521-8. PMID: 2803268.
      Citations:    
    277. Diaz A, Varga J, Jimenez SA. Transforming growth factor-beta stimulation of lung fibroblast prostaglandin E2 production. J Biol Chem. 1989 Jul 15; 264(20):11554-7. PMID: 2745404.
      Citations:    
    278. Bashey RI, Leach RM, Gay CV, Jimenez SA. Type X collagen in avian tibial dyschondroplasia. Lab Invest. 1989 Jan; 60(1):106-12. PMID: 2911181.
      Citations:    
    279. Lally EV, Jimenez SA. Vocal cord palsy in systemic sclerosis. J Rheumatol. 1988 Dec; 15(12):1876-7. PMID: 3230575.
      Citations:    
    280. Lally EV, Jimenez SA, Kaplan SR. Progressive systemic sclerosis: mode of presentation, rapidly progressive disease course, and mortality based on an analysis of 91 patients. Semin Arthritis Rheum. 1988 Aug; 18(1):1-13. PMID: 3187542.
      Citations:    
    281. Reginato AM, Shapiro IM, Lash JW, Jimenez SA. Type X collagen alterations in rachitic chick epiphyseal growth cartilage. J Biol Chem. 1988 Jul 15; 263(20):9938-45. PMID: 3133372.
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    282. Varga J, Rosenbloom J, Jimenez SA. Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. Biochem J. 1987 Nov 01; 247(3):597-604. PMID: 3501287.
      Citations:    
    283. Varga J, Diaz-Perez A, Rosenbloom J, Jimenez SA. PGE2 causes a coordinate decrease in the steady state levels of fibronectin and types I and III procollagen mRNAs in normal human dermal fibroblasts. Biochem Biophys Res Commun. 1987 Sep 30; 147(3):1282-8. PMID: 3478047.
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    284. Freundlich B, Jimenez SA. Phenotype of peripheral blood lymphocytes in patients with progressive systemic sclerosis: activated T lymphocytes and the effect of D-penicillamine therapy. Clin Exp Immunol. 1987 Aug; 69(2):375-84. PMID: 3498592.
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    285. Varga J, Jimenez SA. Cutaneous sclerosis localized to one limb after immobilization in a patient with CREST syndrome. J Rheumatol. 1987 Jun; 14(3):637-8. PMID: 3625655.
      Citations:    
    286. Elias JA, Jimenez SA, Freundlich B. Recombinant gamma, alpha, and beta interferon regulation of human lung fibroblast proliferation. Am Rev Respir Dis. 1987 Jan; 135(1):62-5. PMID: 3099617.
      Citations:    
    287. Katzka DA, Reynolds JC, Saul SH, Plotkin A, Lang CA, Ouyang A, Jimenez S, Cohen S. Barrett's metaplasia and adenocarcinoma of the esophagus in scleroderma. Am J Med. 1987 Jan; 82(1):46-52. PMID: 3799692.
      Citations:    
    288. Ntoso KA, Tomaszewski JE, Jimenez SA, Neilson EG. Penicillamine-induced rapidly progressive glomerulonephritis in patients with progressive systemic sclerosis: successful treatment of two patients and a review of the literature. Am J Kidney Dis. 1986 Sep; 8(3):159-63. PMID: 3752071.
      Citations:    
    289. Varga J, Jimenez SA. Development of severe limited scleroderma in complicated Raynaud's phenomenon after limb immobilization: report of two cases and study of collagen biosynthesis. Arthritis Rheum. 1986 Sep; 29(9):1160-5. PMID: 3753543.
      Citations:    
    290. Jimenez SA, Feldman G, Bashey RI, Bienkowski R, Rosenbloom J. Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts. Biochem J. 1986 Aug 01; 237(3):837-43. PMID: 3800922.
      Citations:    
    291. Varga J, Jimenez SA. Stimulation of normal human fibroblast collagen production and processing by transforming growth factor-beta. Biochem Biophys Res Commun. 1986 Jul 31; 138(2):974-80. PMID: 3461787.
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    292. Jimenez SA, Rao VH, Reginato AM, Yankowski R. Identification of a disulfide-bonded 70 Kd type X procollagen in embryonic chick sternum cartilage. Biochem Biophys Res Commun. 1986 Jul 31; 138(2):835-41. PMID: 3741436.
      Citations:    
    293. Rosenbloom J, Feldman G, Freundlich B, Jimenez SA. Inhibition of excessive scleroderma fibroblast collagen production by recombinant gamma-interferon. Association with a coordinate decrease in types I and III procollagen messenger RNA levels. Arthritis Rheum. 1986 Jul; 29(7):851-6. PMID: 3091039.
      Citations:    
    294. Maul GG, French BT, van Venrooij WJ, Jimenez SA. Topoisomerase I identified by scleroderma 70 antisera: enrichment of topoisomerase I at the centromere in mouse mitotic cells before anaphase. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5145-9. PMID: 3014535.
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    295. Reginato AM, Lash JW, Jimenez SA. Expression of type X collagen mRNA levels in embryonic chick sternum during development. Biochem Biophys Res Commun. 1986 Jun 30; 137(3):1125-32. PMID: 3524567.
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    296. Jimenez SA, Williams CJ, Myers JC, Bashey RI. Increased collagen biosynthesis and increased expression of type I and type III procollagen genes in tight skin (TSK) mouse fibroblasts. J Biol Chem. 1986 Jan 15; 261(2):657-62. PMID: 2416757.
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    297. Jimenez SA, Yankowski R, Reginato AM. Quantitative analysis of type X-collagen biosynthesis by embryonic-chick sternal cartilage. Biochem J. 1986 Jan 15; 233(2):357-67. PMID: 3954741.
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    298. Wolf B, Bashey RI, Newton CD, Jimenez SA. Development of rheumatoid factors and anti-F(ab')2 antibodies in guinea pigs immunized with type II bovine collagen. Int Arch Allergy Appl Immunol. 1986; 80(2):214-20. PMID: 2940189.
      Citations:    
    299. Jimenez SA, McArthur WM, Bashey RI, Rosenbloom J. Selective inhibition of excessive scleroderma fibroblast collagen production by lymphokines from normal human mononuclear cells. Arthritis Rheum. 1985 May; 28(5):502-10. PMID: 4004960.
      Citations:    
    300. Jimenez SA, Rosenbloom J. Production of collagen synthesis inhibitory lymphokine by human leukemic T-lymphocyte cell lines. Immunol Lett. 1985; 11(2):69-74. PMID: 3878830.
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    301. Remington MC, Bashey RI, Brighton CT, Jimenez SA. Biosynthesis of a disulphide-bonded short-chain collagen by calf growth-plate cartilage. Biochem J. 1984 Nov 15; 224(1):227-33. PMID: 6095816.
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    302. Bashey RI, Millan A, Jimenez SA. Increased biosynthesis of glycosaminoglycans by scleroderma fibroblasts in culture. Arthritis Rheum. 1984 Sep; 27(9):1040-5. PMID: 6477654.
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    303. Jimenez SA, Freundlich B, Rosenbloom J. Selective inhibition of human diploid fibroblast collagen synthesis by interferons. J Clin Invest. 1984 Sep; 74(3):1112-6. PMID: 6432846.
      Citations:    
    304. Rosenbloom J, Feldman G, Freundlich B, Jimenez SA. Transcriptional control of human diploid fibroblast collagen synthesis by gamma-interferon. Biochem Biophys Res Commun. 1984 Aug 30; 123(1):365-72. PMID: 6433919.
      Citations:    
    305. Bomalaski JS, Jimenez SA. Erosive arthritis of the temporomandibular joint in Reiter's syndrome. J Rheumatol. 1984 Jun; 11(3):400-2. PMID: 6737384.
      Citations:    
    306. Lugano EM, Dauber JH, Elias JA, Bashey RI, Jimenez SA, Daniele RP. The regulation of lung fibroblast proliferation by alveolar macrophages in experimental silicosis. Am Rev Respir Dis. 1984 May; 129(5):767-71. PMID: 6721274.
      Citations:    
    307. Jimenez SA, Millan A, Bashey RI. Scleroderma-like alterations in collagen metabolism occurring in the TSK (tight skin) mouse. Arthritis Rheum. 1984 Feb; 27(2):180-5. PMID: 6696773.
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    308. Rosenbloom J, McArthur W, Malamud D, Jimenez S. Characterization of a lymphokine produced by human T cells which inhibits collagen synthesis. Cell Immunol. 1983 Oct 01; 81(1):192-8. PMID: 6604586.
      Citations:    
    309. Bashey RI, Herold RA, Jimenez SA. Biochemical characterization of collagens and of a non-collagenous protein synthesized by guinea pig lung fibroblasts in culture. Connect Tissue Res. 1983; 12(1):17-31. PMID: 6671379.
      Citations:    
    310. McArthur W, Derr K, Dixon M, Jimenez SA, Rosenbloom J. Immune modulation of connective tissue functions: studies on the production of collagen synthesis inhibitory factor by populations of human peripheral blood mononuclear cells. Cell Immunol. 1982 Nov 15; 74(1):126-39. PMID: 6819090.
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    311. Nielson EG, Phillips SM, Jimenez S. Lymphokine modulation of fibroblast proliferation. J Immunol. 1982 Mar; 128(3):1484-6. PMID: 7057039.
      Citations:    
    312. Yoshimura M, Jimenez SA, Kaji A. Effects of viral transformation on synthesis and secretion of collagen and fibronectin-like molecules by embryonic chick chondrocytes in culture. J Biol Chem. 1981 Sep 10; 256(17):9111-7. PMID: 6267062.
      Citations:    
    313. Lally EV, Jimenez SA. Impotence in progressively systemic sclerosis. Ann Intern Med. 1981 Aug; 95(2):150-3. PMID: 6789736.
      Citations:    
    314. Dauber JH, Rossman MD, Pietra GG, Jimenez SA, Daniele RP. Experimental silicosis: morphologic and biochemical abnormalities produced by intratracheal instillation of quartz into guinea pig lungs. Am J Pathol. 1980 Dec; 101(3):595-612. PMID: 6255801.
      Citations:    
    315. Neilson EG, Jimenez SA, Phillips SM. Cell-mediated immunity in interstitial nephritis. III. T lymphocyte-mediated fibroblast proliferation and collagen synthesis: an immune mechanism for renal fibrogenesis. J Immunol. 1980 Oct; 125(4):1708-14. PMID: 6967914.
      Citations:    
    316. Kronick P, Jimenez SA. The size of collagen fibrils that stimulate platelet aggregation in human plasma. Biochem J. 1980 Jan 15; 186(1):5-12. PMID: 7370021.
      Citations:    
    317. Jimenez S, Benditt M, Yankowski R, Christner P. Effect of various aminoacid analogues on chick tendon procollagen synthesis and secretion: selective inhibition by S-2-aminoethyl cysteine. Biochem Biophys Res Commun. 1979 Dec 28; 91(4):1330-6. PMID: 526306.
      Citations:    
    318. Jimenez SA, McArthur W, Rosenbloom J. Inhibition of collagen synthesis by mononuclear cell supernates. J Exp Med. 1979 Dec 01; 150(6):1421-31. PMID: 229188.
      Citations:    
    319. Sampson PM, Jimenez SA, Bashey RI. Isolation and partial characterization of proteoglycans from sheep lung parenchyma. Biochim Biophys Acta. 1979 Nov 15; 588(1):129-41. PMID: 497241.
      Citations:    
    320. Brighton CT, Shadle CA, Jimenez SA, Irwin JT, Lane JM, Lipton M. Articular cartilage preservation and storage. I. Application of tissue culture techniques to the storage of viable articular cartilage. Arthritis Rheum. 1979 Oct; 22(10):1093-101. PMID: 90509.
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    321. Reginato AJ, Schumacher HR, Jimenez S, Maurer K. Synovitis in secondary syphilis. Clinical, light, and electron microscopic studies. Arthritis Rheum. 1979 Feb; 22(2):170-6. PMID: 369568.
      Citations:    
    322. Bashey RI, Bashey HM, Jimenez SA. Characterization of pepsin-solubilized bovine heart-valve collagen. Biochem J. 1978 Sep 01; 173(3):885-94. PMID: 361035.
      Citations:    
    323. Jimenez SA, Bashey RI. Solubilization of bovine heart-value collagen. Biochem J. 1978 Jul 01; 173(1):337-40. PMID: 356854.
      Citations:    
    324. Jimenez SA, Yankowski R, Bashey RI. Identification of two new collagen alpha-chains in extracts of lathyritic chick embryo tendons. Biochem Biophys Res Commun. 1978 Apr 28; 81(4):1298-306. PMID: 666820.
      Citations:    
    325. Howell DS, Woessner JF, Jimenez S, Seda H, Schumacher HR. A view on the pathogenesis of osteoarthritis. Bull Rheum Dis. 1978-1979; 29(8):996-1001. PMID: 754840.
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    326. Jimenez SA, Bashey RI, Benditt M, Yankowski R. Identification of collagen alpha1(I) trimer in embryonic chick tendons and calvaria. Biochem Biophys Res Commun. 1977 Oct 24; 78(4):1354-61. PMID: 562664.
      Citations:    
    327. Bashey RI, Jimenez SA. Increased sensitivity of scleroderma fibroblasts in culture to stimulation of protein and collagen synthesis by serum. Biochem Biophys Res Commun. 1977 Jun 20; 76(4):1214-22. PMID: 901473.
      Citations:    
    328. Jimenez SA, Bashey RI. Collagen synthesis by scleroderma fibroblasts in culture. Arthritis Rheum. 1977 Apr; 20(3):902-3. PMID: 856221.
      Citations:    
    329. Gasic GJ, Gasic TB, Jimenez SA. Platelet aggregating material in mouse tumor cells. Removal and regeneration. Lab Invest. 1977 Apr; 36(4):413-9. PMID: 191695.
      Citations:    
    330. Gibson T, Sims HP, Jimenez SA. Hypouricaemia and increased renal urate clearance associated with hyperparathyroidism. Ann Rheum Dis. 1976 Aug; 35(4):372-6. PMID: 970997.
      Citations:    
    331. Jimenez SA, Yankowski R. Secretion of unhydroxylated chick tendon procollagen. Biochem Biophys Res Commun. 1975 Nov 17; 67(2):735-40. PMID: 1239287.
      Citations:    
    332. Jimenez S, Rosenbloom J. Decreased thermal stability of collagens containing analogs of proline or lysine. Arch Biochem Biophys. 1974 Aug; 163(2):459-65. PMID: 4606409.
      Citations:    
    333. Jimenez SA, Harsch M, Murphy L, Rosenbloom J. Effects of temperature on conformation, hydroxylation, and secretion of chick tendon procollagen. J Biol Chem. 1974 Jul 25; 249(14):4480-6. PMID: 4367217.
      Citations:    
    334. Rosenbloom J, Harsch M, Jimenez S. Hydroxyproline content determines the denaturation temperature of chick tendon collagen. Arch Biochem Biophys. 1973 Oct; 158(2):478-84. PMID: 4592982.
      Citations:    
    335. Ramaley PB, Jimenez SA, Rosenbloom J. Conformation of underhydroxylated collagen synthesized by 3T6 fibroblasts in culture. FEBS Lett. 1973 Jul 01; 33(2):187-91. PMID: 4738097.
      Citations:    
    336. Jimenez S, Harsch M, Rosenbloom J. Hydroxyproline stabilizes the triple helix of chick tendon collagen. Biochem Biophys Res Commun. 1973 May 01; 52(1):106-14. PMID: 4576266.
      Citations:    
    337. Uitto J, Jimenez SA, Dehm P, Prockop DJ. Characterization of the precursor forms of the 1 and 2 chains of collagen from matrix-free tendon cells. Biochim Biophys Acta. 1972 Aug 31; 278(1):198-205. PMID: 4672181.
      Citations:    
    338. Dehm P, Jimenez SA, Olsen BR, Prockop DJ. A transport form of collagen from embryonic tendon: electron microscopic demonstration of an NH 2 -terminal extension and evidence suggesting the presence of cystine in the molecule (chick embryo-tropocollagen-gel filtration). Proc Natl Acad Sci U S A. 1972 Jan; 69(1):60-4. PMID: 4333046.
      Citations:    
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