Thomas Jefferson University

Ulrich Rodeck

TitleAssoc Prof CHP
InstitutionThomas Jefferson University
DepartmentNursing - Undergraduate
Address233 S. 10th Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jenkins KA, Park M, Pederzoli-Ribeil M, Eskiocak U, Johnson P, Guzman W, McLaughlin M, Moore-Lai D, O'Toole C, Liu Z, Nicholson B, Flesch V, Qiu H, Clackson T, O'Hagan RC, Rodeck U, Karow M, O'Neil J, Williams JC. XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer. J Immunother Cancer. 2023 12 12; 11(12). PMID: 38164757.
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    2. Luginbuhl AJ, Johnson JM, Harshyne LA, Linnenbach AJ, Shukla SK, Alnemri A, Kumar G, Cognetti DM, Curry JM, Kotlov N, Antysheva Z, Degryse S, Mannion K, Gibson MK, Netterville J, Brown B, Axelrod R, Zinner R, Tuluc M, Gargano S, Leiby BE, Shimada A, Mahoney MG, Martinez-Outschoorn U, Rodeck U, Kim YJ, South AP, Argiris A. Tadalafil Enhances Immune Signatures in Response to Neoadjuvant Nivolumab in Resectable Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2022 Mar 01; 28(5):915-927. PMID: 34911681.
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    3. Luginbuhl AJ, Hobelmann K, Rodin J, Shukla S, Rodeck U, Linnenbach A. Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue. Laryngoscope. 2021 Oct 28. PMID: 34709651.
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    4. Manukian G, Kivolowitz C, DeAngelis T, Shastri AA, Savage JE, Camphausen K, Rodeck U, Zarif JC, Simone NL. Caloric Restriction Impairs Regulatory T cells Within the Tumor Microenvironment After Radiation and Primes Effector T cells. Int J Radiat Oncol Biol Phys. 2021 Feb 26. PMID: 33647370.
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    5. Merlino DJ, Johnson JM, Tuluc M, Gargano S, Stapp R, Harshyne L, Leiby BE, Flanders A, Zinner R, Axelrod R, Curry J, Cognetti DM, Mannion K, Kim YJ, Rodeck U, Argiris A, Luginbuhl AJ. Discordant Responses Between Primary Head and Neck Tumors and Nodal Metastases Treated With Neoadjuvant Nivolumab: Correlation of Radiographic and Pathologic Treatment Effect. Front Oncol. 2020; 10:566315. PMID: 33344227.
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    6. Knops AM, South A, Rodeck U, Martinez-Outschoorn U, Harshyne LA, Johnson J, Luginbuhl AJ, Curry JM. Cancer-Associated Fibroblast Density, Prognostic Characteristics, and Recurrence in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis. Front Oncol. 2020; 10:565306. PMID: 33330034.
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    7. Wright CM, Shastri AA, Bongiorno E, Palagani A, Rodeck U, Simone NL. Is Host Metabolism the Missing Link to Improving Cancer Outcomes? Cancers (Basel). 2020 Aug 19; 12(9). PMID: 32825010.
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    8. Flemming JP, Hill BL, Haque MW, Raad J, Bonder CS, Harshyne LA, Rodeck U, Luginbuhl A, Wahl JK, Tsai KY, Wermuth PJ, Overmiller AM, Mahoney MG. miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas. J Extracell Vesicles. 2020 Jul 13; 9(1):1790159. PMID: 32944178.
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    9. Nevler A, Brown SZ, Nauheim D, Portocarrero C, Bassig J, Schultz CW, McCarthy G, Lavu H, Yeo TP, Yeo CJ, Brody JR. Effect of Hypercapnia, an Element of Obstructive Respiratory Disorders, on Pancreatic Cancer Chemoresistance and Progression. J Am Coll Surg. 2020 Feb 10. PMID: 32058016.
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    10. Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB. A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation. J Biol Chem. 2020 Jan 21. PMID: 31964716.
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    11. Erkes DA, Cai W, Sanchez IM, Purwin TJ, Rogers C, Field CO, Berger AC, Hartsough EJ, Rodeck U, Alnemri ES, Aplin AE. Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis. Cancer Discov. 2019 Dec 03. PMID: 31796433.
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    12. Amin D, Richa T, Mollaee M, Zhan T, Tassone P, Johnson J, Luginbuhl A, Cognetti D, Martinez-Outschoorn U, Stapp R, Solomides C, Rodeck U, Curry J. Metformin effects on FOXP3+ and CD8+ T cell infiltrates of head and neck squamous cell carcinoma. Laryngoscope. 2019 Oct 08. PMID: 31593308.
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    13. Kumar AT, Knops A, Swendseid B, Martinez-Outschoom U, Harshyne L, Philp N, Rodeck U, Luginbuhl A, Cognetti D, Johnson J, Curry J. Prognostic Significance of Tumor-Associated Macrophage Content in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis. Front Oncol. 2019; 9:656. PMID: 31396482.
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    14. DeRita RM, Sayeed A, Garcia V, Krishn SR, Shields CD, Sarker S, Friedman A, McCue P, Molugu SK, Rodeck U, Dicker AP, Languino LR. Tumor-Derived Extracellular Vesicles Require ß1 Integrins to Promote Anchorage-Independent Growth. iScience. 2019 Apr 26; 14:199-209. PMID: 30981115.
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    15. Topf MC, Harshyne L, Tuluc M, Mardekian S, Vimawala S, Cognetti DM, Curry JM, Rodeck U, Luginbuhl A. Loss of CD169+ Subcapsular Macrophages during Metastatic Spread of Head and Neck Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2019 Feb 12; 194599819829741. PMID: 30744470.
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    16. Curry JM, Johnson J, Mollaee M, Tassone P, Amin D, Knops A, Whitaker-Menezes D, Mahoney MG, South A, Rodeck U, Zhan T, Harshyne L, Philp N, Luginbuhl A, Cognetti D, Tuluc M, Martinez-Outschoorn U. Metformin Clinical Trial in HPV+ and HPV- Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate. Front Oncol. 2018; 8:436. PMID: 30364350.
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    17. Gubbiotti MA, Seifert E, Rodeck U, Hoek JB, Iozzo RV. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. J Biol Chem. 2018 Oct 26; 293(43):16940-16950. PMID: 30049794.
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    18. Flickinger JC, Rodeck U, Snook AE. Listeria monocytogenes as a Vector for Cancer Immunotherapy: Current Understanding and Progress. Vaccines (Basel). 2018 Jul 25; 6(3). PMID: 30044426.
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    19. Maranto C, Udhane V, Hoang DT, Gu L, Alexeev V, Malas K, Cardenas K, Brody JR, Rodeck U, Bergom C, Iczkowski KA, Jacobsohn K, See W, Schmitt SM, Nevalainen MT. STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation through Inhibition of RAD51 and DNA Repair. Clin Cancer Res. 2018 Feb 26. PMID: 29483142.
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    20. Alfego D, Rodeck U, Kriete A. Global mapping of transcription factor motifs in human aging. PLoS One. 2018; 13(1):e0190457. PMID: 29293662.
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    21. Curry J, Tassone P, Gill K, Tuluc M, BarAd V, Mollaee M, Whitaker-Menezes D, Rodeck U, Luginbuhl A, Cognetti D, Keane W, Martinez-Outschoorn U. Tumor Metabolism in the Microenvironment of Nodal Metastasis in Oral Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2017 Jun 01; 194599817709224. PMID: 28608777.
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    22. Yalamanchili N, Kriete A, Alfego D, Danowski KM, Kari C, Rodeck U. Distinct Cell Stress Responses Induced by ATP Restriction in Quiescent Human Fibroblasts. Front Genet. 2016; 7:171. PMID: 27757122.
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    23. Sayeed A, Lu H, Liu Q, Deming D, Duffy A, McCue P, Dicker AP, Davis RJ, Gabrilovich D, Rodeck U, Altieri DC, Languino LR. ß1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation. Oncotarget. 2016 Aug 16; 7(33):52618-52630. PMID: 27438371.
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    24. Chan TO, Zhang J, Tiegs BC, Blumhof B, Yan L, Keny N, Penny M, Li X, Pascal JM, Armen RS, Rodeck U, Penn RB. Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response. Biochem J. 2015 Oct 1; 471(1):37-51. PMID: 26201515.
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    25. Goldman DC, Alexeev V, Lash E, Guha C, Rodeck U, Fleming WH. The Triterpenoid RTA 408 is a Robust Mitigator of Hematopoietic Acute Radiation Syndrome in Mice. Radiat Res. 2015 Mar; 183(3):338-44. PMID: 25738896.
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    26. Alexeev V, Lash E, Aguillard A, Corsini L, Bitterman A, Ward K, Dicker AP, Linnenbach A, Rodeck U. Radiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound. Mol Cancer Ther. 2014 Dec; 13(12):2968-77. PMID: 25398830.
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    27. Lacouture ME, Rodeck U. Skinflammation and drug toxicity--a delicate balance. Sci Transl Med. 2013 Aug 21; 5(199):199fs33. PMID: 23966298.
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    28. Belum VR, Fontanilla Patel H, Lacouture ME, Rodeck U. Skin toxicity of targeted cancer agents: mechanisms and intervention. Future Oncol. 2013 Aug; 9(8):1161-70. PMID: 23902247.
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    29. Le K, Blomain ES, Rodeck U, Aplin AE. Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells. Pigment Cell Melanoma Res. 2013 Jul; 26(4):509-17. PMID: 23490205.
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    30. Igoucheva O, Grazzini M, Pidich A, Kemp DM, Larijani M, Farber M, Lorton J, Rodeck U, Alexeev V. Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine. Gene Ther. 2013 Sep; 20(9):939-48. PMID: 23552473.
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    31. Fertig EJ, Ren Q, Cheng H, Hatakeyama H, Dicker AP, Rodeck U, Considine M, Ochs MF, Chung CH. Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma. BMC Genomics. 2012; 13:160. PMID: 22549044.
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    32. Uitto J, Rodeck U. Integration of investigative dermatology into the global biomedical research enterprise: past, present, and future. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):1029-32. PMID: 22330270.
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    33. Chan TO, Pascal JM, Armen RS, Rodeck U. Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases. Cell Cycle. 2012 Feb 1; 11(3):475-8. PMID: 22262182.
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    34. Chan TO, Zhang J, Rodeck U, Pascal JM, Armen RS, Spring M, Dumitru CD, Myers V, Li X, Cheung JY, Feldman AM. Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):E1120-7. PMID: 22031698.
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    35. Cheng H, Kari G, Dicker AP, Rodeck U, Koch WJ, Force T. A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity. Circ Res. 2011 Dec 9; 109(12):1401-9. PMID: 21998323.
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    36. Sadri K, Ren Q, Zhang K, Paudyal B, Devadhas D, Rodeck U, Thakur M. PET imaging of EGFR expression in nude mice bearing MDA-MB-468, a human breast adenocarcinoma. Nucl Med Commun. 2011 Jul; 32(7):563-9. PMID: 21572364.
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    37. Davidson WR, Kari C, Ren Q, Daroczi B, Dicker AP, Rodeck U. Differential regulation of p53 function by the N-terminal ?Np53 and ?113p53 isoforms in zebrafish embryos. BMC Dev Biol. 2010; 10:102. PMID: 20929554.
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    38. Zhou Z, Joslin S, Dellinger A, Ehrich M, Brooks B, Ren Q, Rodeck U, Lenk R, Kepley CL. A novel class of compounds with cutaneous wound healing properties. J Biomed Nanotechnol. 2010 Oct; 6(5):605-11. PMID: 21329053.
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    39. Uitto J, McGrath JA, Rodeck U, Bruckner-Tuderman L, Robinson EC. Progress in epidermolysis bullosa research: toward treatment and cure. J Invest Dermatol. 2010 Jul; 130(7):1778-84. PMID: 20393479.
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    40. Donaldson JM, Kari C, Fragoso RC, Rodeck U, Williams JC. Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies. Cancer Biol Ther. 2009 Nov; 8(22):2147-52. PMID: 19783899.
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    41. Daroczi B, Kari G, Ren Q, Dicker AP, Rodeck U. Nuclear factor kappaB inhibitors alleviate and the proteasome inhibitor PS-341 exacerbates radiation toxicity in zebrafish embryos. Mol Cancer Ther. 2009 Sep; 8(9):2625-34. PMID: 19723885.
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    42. Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR. Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice. Cancer Res. 2009 Jul 15; 69(14):5643-7. PMID: 19584274.
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    43. Lightcap CM, Kari G, Arias-Romero LE, Chernoff J, Rodeck U, Williams JC. Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development. PLoS One. 2009; 4(6):e6025. PMID: 19557173.
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    44. Rodeck U. Skin toxicity caused by EGFR antagonists-an autoinflammatory condition triggered by deregulated IL-1 signaling? J Cell Physiol. 2009 Jan; 218(1):32-4. PMID: 18781585.
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    45. Rodeck U, Williams JC. Nature's design: A blueprint for engineered therapeutic antibodies. Cancer Biol Ther. 2008 Nov; 7(11):1751-2. PMID: 18981729.
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    46. Lightcap CM, Sun S, Lear JD, Rodeck U, Polenova T, Williams JC. Biochemical and structural characterization of the Pak1-LC8 interaction. J Biol Chem. 2008 Oct 3; 283(40):27314-24. PMID: 18650427.
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    47. Kriete A, Mayo KL, Yalamanchili N, Beggs W, Bender P, Kari C, Rodeck U. Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity. Immun Ageing. 2008; 5:5. PMID: 18631391.
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    48. Hintze V, Steplewski A, Ito H, Jensen DA, Rodeck U, Fertala A. Cells expressing partially unfolded R789C/p.R989C type II procollagen mutant associated with spondyloepiphyseal dysplasia undergo apoptosis. Hum Mutat. 2008 Jun; 29(6):841-51. PMID: 18383211.
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    49. Kamat V, Donaldson JM, Kari C, Quadros MR, Lelkes PI, Chaiken I, Cocklin S, Williams JC, Papazoglou E, Rodeck U. Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425. Cancer Biol Ther. 2008 May; 7(5):726-33. PMID: 18424917.
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    50. Davidson W, Ren Q, Kari G, Kashi O, Dicker AP, Rodeck U. Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos. Cell Cycle. 2008 May 1; 7(9):1224-30. PMID: 18418056.
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    51. Rodeck U, Uitto J. Recessive dystrophic epidermolysis bullosa-associated squamous-cell carcinoma: an enigmatic entity with complex pathogenesis. J Invest Dermatol. 2007 Oct; 127(10):2295-6. PMID: 17853916.
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    52. Rodeck U, Fertala A, Uitto J. Anchorless keratinocyte survival: an emerging pathogenic mechanism for squamous cell carcinoma in recessive dystrophic epidermolysis bullosa. Exp Dermatol. 2007 Jun; 16(6):465-7. PMID: 17518985.
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    53. Kari G, Rodeck U, Dicker AP. Zebrafish: an emerging model system for human disease and drug discovery. Clin Pharmacol Ther. 2007 Jul; 82(1):70-80. PMID: 17495877.
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    54. Brennan D, Hu Y, Joubeh S, Choi YW, Whitaker-Menezes D, O'Brien T, Uitto J, Rodeck U, Mahoney MG. Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes. J Cell Sci. 2007 Mar 1; 120(Pt 5):758-71. PMID: 17284515.
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    55. Chung CH, Parker J, Levy S, Slebos RJ, Dicker AP, Rodeck U. Gene expression profiles as markers of aggressive disease-EGFR as a factor. Int J Radiat Oncol Biol Phys. 2007; 69(2 Suppl):S102-5. PMID: 17848272.
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    56. Daroczi B, Kari G, McAleer MF, Wolf JC, Rodeck U, Dicker AP. In vivo radioprotection by the fullerene nanoparticle DF-1 as assessed in a zebrafish model. Clin Cancer Res. 2006 Dec 1; 12(23):7086-91. PMID: 17145832.
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    57. Bellone G, Carbone A, Smirne C, Scirelli T, Buffolino A, Novarino A, Stacchini A, Bertetto O, Palestro G, Sorio C, Scarpa A, Emanuelli G, Rodeck U. Cooperative induction of a tolerogenic dendritic cell phenotype by cytokines secreted by pancreatic carcinoma cells. J Immunol. 2006 Sep 1; 177(5):3448-60. PMID: 16920987.
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    58. McAleer MF, Duffy KT, Davidson WR, Kari G, Dicker AP, Rodeck U, Wickstrom E. Antisense inhibition of cyclin D1 expression is equivalent to flavopiridol for radiosensitization of zebrafish embryos. Int J Radiat Oncol Biol Phys. 2006 Oct 1; 66(2):546-51. PMID: 16904844.
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    59. Ren Q, Kari C, Quadros MR, Burd R, McCue P, Dicker AP, Rodeck U. Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling. Cancer Res. 2006 May 15; 66(10):5209-15. PMID: 16707445.
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    60. Quadros MR, Connelly S, Kari C, Abrams MT, Wickstrom E, Rodeck U. EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities. Cancer Biol Ther. 2006 May; 5(5):498-504. PMID: 16582597.
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    61. Zhang W, Alt-Holland A, Margulis A, Shamis Y, Fusenig NE, Rodeck U, Garlick JA. E-cadherin loss promotes the initiation of squamous cell carcinoma invasion through modulation of integrin-mediated adhesion. J Cell Sci. 2006 Jan 15; 119(Pt 2):283-91. PMID: 16390868.
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    62. Duffy KT, McAleer MF, Davidson WR, Kari L, Kari C, Liu CG, Farber SA, Cheng KC, Mest JR, Wickstrom E, Dicker AP, Rodeck U. Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids. Nucleic Acids Res. 2005; 33(15):4914-21. PMID: 16284195.
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    63. Dicker AP, Rodeck U. Predicting the future from trials of the past: epidermal growth factor receptor expression and outcome of fractionated radiation therapy trials. J Clin Oncol. 2005 Aug 20; 23(24):5437-9. PMID: 16110005.
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    64. Carbone A, Rodeck U, Mauri FA, Sozzi M, Gaspari F, Smirne C, Prati A, Addeo A, Novarino A, Robecchi A, Bertetto O, Emanuelli G, Bellone G. Human pancreatic carcinoma cells secrete bioactive interleukin-18 after treatment with 5-fluorouracil: implications for anti-tumor immune response. Cancer Biol Ther. 2005 Feb; 4(2):231-41. PMID: 15684607.
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    65. Jost M, Rodeck U. Keratinocyte culture in the absence of substrate attachment. Methods Mol Biol. 2005; 289:23-8. PMID: 15502166.
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    66. McAleer MF, Davidson C, Davidson WR, Yentzer B, Farber SA, Rodeck U, Dicker AP. Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers. Int J Radiat Oncol Biol Phys. 2005 Jan 1; 61(1):10-3. PMID: 15629588.
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    67. Quadros MR, Peruzzi F, Kari C, Rodeck U. Complex regulation of signal transducers and activators of transcription 3 activation in normal and malignant keratinocytes. Cancer Res. 2004 Jun 1; 64(11):3934-9. PMID: 15173005.
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    68. Bellone G, Ferrero D, Carbone A, De Quadros MR, Gramigni C, Prati A, Davidson W, Mioli P, Dughera L, Emanuelli G, Rodeck U. Inhibition of cell survival and invasive potential of colorectal carcinoma cells by the tyrosine kinase inhibitor STI571. Cancer Biol Ther. 2004 Apr; 3(4):385-92. PMID: 14726674.
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    69. Dicker AP, Rodeck U. Targeting the EGFR in neoplasia--more questions than answers. Int J Radiat Oncol Biol Phys. 2004 Mar 1; 58(3):899-902. PMID: 14967449.
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    70. Rodeck U. Extracellular matrix composition modulates cell cycle checkpoint control: a new twist to radiation sensitivity. Cancer Biol Ther. 2004 Jan; 3(1):54. PMID: 14726701.
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    71. Rouan F, Lo CW, Fertala A, Wahl M, Jost M, Rodeck U, Uitto J, Richard G. Divergent effects of two sequence variants of GJB3 (G12D and R32W) on the function of connexin 31 in vitro. Exp Dermatol. 2003 Apr; 12(2):191-7. PMID: 12702148.
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    72. Kari C, Chan TO, Rocha de Quadros M, Rodeck U. Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. Cancer Res. 2003 Jan 1; 63(1):1-5. PMID: 12517767.
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    73. Emrich JG, Brady LW, Quang TS, Class R, Miyamoto C, Black P, Rodeck U. Radioiodinated (I-125) monoclonal antibody 425 in the treatment of high grade glioma patients: ten-year synopsis of a novel treatment. Am J Clin Oncol. 2002 Dec; 25(6):541-6. PMID: 12477994.
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    74. Pistritto G, Jost M, Srinivasula SM, Baffa R, Poyet JL, Kari C, Lazebnik Y, Rodeck U, Alnemri ES. Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. Cell Death Differ. 2002 Sep; 9(9):995-1006. PMID: 12181750.
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    75. Wahl ML, Owen JA, Burd R, Herlands RA, Nogami SS, Rodeck U, Berd D, Leeper DB, Owen CS. Regulation of intracellular pH in human melanoma: potential therapeutic implications. Mol Cancer Ther. 2002 Jun; 1(8):617-28. PMID: 12479222.
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    76. Aho S, Levänsuo L, Montonen O, Kari C, Rodeck U, Uitto J. Specific sequences in p120ctn determine subcellular distribution of its multiple isoforms involved in cellular adhesion of normal and malignant epithelial cells. J Cell Sci. 2002 Apr 1; 115(Pt 7):1391-402. PMID: 11896187.
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    77. Mahoney MG, Simpson A, Jost M, Noé M, Kari C, Pepe D, Choi YW, Uitto J, Rodeck U. Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytes. Oncogene. 2002 Mar 28; 21(14):2161-70. PMID: 11948399.
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    78. Chan TO, Rodeck U, Chan AM, Kimmelman AC, Rittenhouse SE, Panayotou G, Tsichlis PN. Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit. Cancer Cell. 2002 Mar; 1(2):181-91. PMID: 12086876.
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    79. Shin I, Bakin AV, Rodeck U, Brunet A, Arteaga CL. Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1. Mol Biol Cell. 2001 Nov; 12(11):3328-39. PMID: 11694570.
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    80. Graeven U, Rodeck U, Karpinski S, Jost M, Philippou S, Schmiegel W. Modulation of angiogenesis and tumorigenicity of human melanocytic cells by vascular endothelial growth factor and basic fibroblast growth factor. Cancer Res. 2001 Oct 1; 61(19):7282-90. PMID: 11585767.
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    81. Simpson A, Uitto J, Rodeck U, Mahoney MG. Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3. Gene. 2001 Jul 25; 273(1):29-39. PMID: 11483358.
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    82. Jost M, Gasparro FP, Jensen PJ, Rodeck U. Keratinocyte apoptosis induced by ultraviolet B radiation and CD95 ligation -- differential protection through epidermal growth factor receptor activation and Bcl-x(L) expression. J Invest Dermatol. 2001 Jun; 116(6):860-6. PMID: 11407972.
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    83. Jost M, Huggett TM, Kari C, Rodeck U. Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway. Mol Biol Cell. 2001 May; 12(5):1519-27. PMID: 11359940.
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    84. Bellone G, Carbone A, Sibona N, Bosco O, Tibaudi D, Smirne C, Martone T, Gramigni C, Camandona M, Emanuelli G, Rodeck U. Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. Cancer Res. 2001 Mar 1; 61(5):2200-6. PMID: 11280787.
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    85. Bellone G, Carbone A, Tibaudi D, Mauri F, Ferrero I, Smirne C, Suman F, Rivetti C, Migliaretti G, Camandona M, Palestro G, Emanuelli G, Rodeck U. Differential expression of transforming growth factors-beta1, -beta2 and -beta3 in human colon carcinoma. Eur J Cancer. 2001 Jan; 37(2):224-33. PMID: 11166150.
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    86. Jost M, Huggett TM, Kari C, Boise LH, Rodeck U. Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway. J Biol Chem. 2001 Mar 2; 276(9):6320-6. PMID: 11098053.
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    87. Jost M, Kari C, Rodeck U. The EGF receptor - an essential regulator of multiple epidermal functions. Eur J Dermatol. 2000 Oct-Nov; 10(7):505-10. PMID: 11056418.
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    88. Graeven U, Rodeck U, Karpinski S, Jost M, Andre N, Schmiegel W. Expression patterns of placenta growth factor in human melanocytic cell lines. J Invest Dermatol. 2000 Jul; 115(1):118-23. PMID: 10886518.
      Citations:    
    89. Bellone G, Smirne C, Carbone A, Mareschi K, Dughera L, Farina EC, Alabiso O, Valente G, Emanuelli G, Rodeck U. Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma. Clin Cancer Res. 2000 Jun; 6(6):2448-55. PMID: 10873098.
      Citations:    
    90. Graeven U, Fiedler W, Karpinski S, Ergün S, Kilic N, Rodeck U, Schmiegel W, Hossfeld DK. Melanoma-associated expression of vascular endothelial growth factor and its receptors FLT-1 and KDR. J Cancer Res Clin Oncol. 1999 Nov; 125(11):621-9. PMID: 10541969.
      Citations:    
    91. Basu A, Rodeck U, Prendergast GC, Howe CC. Loss of insulin-like growth factor I receptor-dependent expression of p107 and cyclin A in cells that lack the extracellular matrix protein secreted protein acidic and rich in cysteine. Cell Growth Differ. 1999 Nov; 10(11):721-8. PMID: 10593648.
      Citations:    
    92. Bellone G, Turletti A, Artusio E, Mareschi K, Carbone A, Tibaudi D, Robecchi A, Emanuelli G, Rodeck U. Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients. Am J Pathol. 1999 Aug; 155(2):537-47. PMID: 10433946.
      Citations:    
    93. Jost M, Class R, Kari C, Jensen PJ, Rodeck U. A central role of Bcl-X(L) in the regulation of keratinocyte survival by autocrine EGFR ligands. J Invest Dermatol. 1999 Apr; 112(4):443-9. PMID: 10201527.
      Citations:    
    94. Rodeck U, Nishiyama T, Mauviel A. Independent regulation of growth and SMAD-mediated transcription by transforming growth factor beta in human melanoma cells. Cancer Res. 1999 Feb 1; 59(3):547-50. PMID: 9973198.
      Citations:    
    95. Endresz V, Kari L, Berencsi K, Kari C, Gyulai Z, Jeney C, Pincus S, Rodeck U, Méric C, Plotkin SA, Gönczöl E. Induction of human cytomegalovirus (HCMV)-glycoprotein B (gB)-specific neutralizing antibody and phosphoprotein 65 (pp65)-specific cytotoxic T lymphocyte responses by naked DNA immunization. Vaccine. 1999 Jan; 17(1):50-8. PMID: 10078607.
      Citations:    
    96. Boxhorn HK, Smith JG, Chang YJ, Guerry D, Lee WM, Rodeck U, Turka LA, Eck SL. Adenoviral transduction of melanoma cells with B7-1: antitumor immunity and immunosuppressive factors. Cancer Immunol Immunother. 1998 Jul; 46(5):283-92. PMID: 9690457.
      Citations:    
    97. Rauscher FJ, Morris JF, Fredericks WJ, Lopez-Guisa J, Balakrishnan C, Jost M, Herlyn M, Rodeck U. Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein. Hybridoma. 1998 Apr; 17(2):191-8. PMID: 9627060.
      Citations:    
    98. Jost M, Kari C, Rodeck U. An episomal vector for stable tetracycline-regulated gene expression. Nucleic Acids Res. 1997 Aug 1; 25(15):3131-4. PMID: 9224615.
      Citations:    
    99. Bellone G, Silvestri S, Artusio E, Tibaudi D, Turletti A, Geuna M, Giachino C, Valente G, Emanuelli G, Rodeck U. Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1. J Cell Physiol. 1997 Jul; 172(1):1-11. PMID: 9207920.
      Citations:    
    100. Rodeck U, Jost M, DuHadaway J, Kari C, Jensen PJ, Risse B, Ewert DL. Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor. Proc Natl Acad Sci U S A. 1997 May 13; 94(10):5067-72. PMID: 9144191.
      Citations:    
    101. Menssen HD, Renkl HJ, Rodeck U, Kari C, Schwartz S, Thiel E. Detection by monoclonal antibodies of the Wilms' tumor (WT1) nuclear protein in patients with acute leukemia. Int J Cancer. 1997 Mar 4; 70(5):518-23. PMID: 9052749.
      Citations:    
    102. Kumar-Singh S, Segers K, Rodeck U, Backhovens H, Bogers J, Weyler J, Van Broeckhoven C, Van Marck E. WT1 mutation in malignant mesothelioma and WT1 immunoreactivity in relation to p53 and growth factor receptor expression, cell-type transition, and prognosis. J Pathol. 1997 Jan; 181(1):67-74. PMID: 9072005.
      Citations:    
    103. Rodeck U, Jost M, Kari C, Shih DT, Lavker RM, Ewert DL, Jensen PJ. EGF-R dependent regulation of keratinocyte survival. J Cell Sci. 1997 Jan; 110 ( Pt 2):113-21. PMID: 9044042.
      Citations:    
    104. Simon HG, Risse B, Jost M, Oppenheimer S, Kari C, Rodeck U. Identification of differentially expressed messenger RNAs in human melanocytes and melanoma cells. Cancer Res. 1996 Jul 1; 56(13):3112-7. PMID: 8674069.
      Citations:    
    105. Sion-Vardy N, Vardy D, Rodeck U, Kari C, Levin RM, Malkowicz SB. Antiproliferative effects of tyrosine kinase inhibitors (tyrphostins) on human bladder and renal carcinoma cells. J Surg Res. 1995 Dec; 59(6):675-80. PMID: 8538164.
      Citations:    
    106. Bellone G, Aste-Amezaga M, Trinchieri G, Rodeck U. Regulation of NK cell functions by TGF-beta 1. J Immunol. 1995 Aug 1; 155(3):1066-73. PMID: 7636180.
      Citations:    
    107. Vardy DA, Kari C, Lazarus GS, Jensen PJ, Zilberstein A, Plowman GD, Rodeck U. Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor-1. J Cell Physiol. 1995 May; 163(2):257-65. PMID: 7706370.
      Citations:    
    108. Amin KM, Litzky LA, Smythe WR, Mooney AM, Morris JM, Mews DJ, Pass HI, Kari C, Rodeck U, Rauscher FJ, et al. Wilms' tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma. Am J Pathol. 1995 Feb; 146(2):344-56. PMID: 7856747.
      Citations:    
    109. Chen CS, Lavker RM, Rodeck U, Risse B, Jensen PJ. Use of a serum-free epidermal culture model to show deleterious effects of epidermal growth factor on morphogenesis and differentiation. J Invest Dermatol. 1995 Jan; 104(1):107-12. PMID: 7798626.
      Citations:    
    110. Rodeck U, Bossler A, Kari C, Humphreys CW, Györfi T, Maurer J, Thiel E, Menssen HD. Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes. Int J Cancer. 1994 Oct 1; 59(1):78-82. PMID: 7927908.
      Citations:    
    111. Rodeck U, Bossler A, Graeven U, Fox FE, Nowell PC, Knabbe C, Kari C. Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells. Cancer Res. 1994 Jan 15; 54(2):575-81. PMID: 8275496.
      Citations:    
    112. Rodeck U. Growth factor independence and growth regulatory pathways in human melanoma development. Cancer Metastasis Rev. 1993 Sep; 12(3-4):219-26. PMID: 8281609.
      Citations:    
    113. Jensen PJ, Rodeck U. Autocrine/paracrine regulation of keratinocyte urokinase plasminogen activator through the TGF-alpha/EGF receptor. J Cell Physiol. 1993 May; 155(2):333-9. PMID: 8482725.
      Citations:    
    114. Schmiegel W, Roeder C, Schmielau J, Rodeck U, Kalthoff H. Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells. Proc Natl Acad Sci U S A. 1993 Feb 1; 90(3):863-7. PMID: 8430098.
      Citations:    
    115. Becker D, Lee PL, Rodeck U, Herlyn M. Inhibition of the fibroblast growth factor receptor 1 (FGFR-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation. Oncogene. 1992 Nov; 7(11):2303-13. PMID: 1437152.
      Citations:    
    116. Valyi-Nagy I, Jensen PJ, Albelda SM, Rodeck U. Cytokine-induced expression of transforming growth factor-alpha and the epidermal growth factor receptor in neonatal skin explants. J Invest Dermatol. 1992 Sep; 99(3):350-6. PMID: 1512472.
      Citations:    
    117. Derui L, Woo DV, Emrich J, Steplewski Z, Rodeck U, Herlyn D, Koprowski H, Miyamoto C, Brady LW. Radiotoxicity of 125I-labeled monoclonal antibody 425 against cancer cells containing epidermal growth factor receptor. Am J Clin Oncol. 1992 Aug; 15(4):288-94. PMID: 1514524.
      Citations:    
    118. Williams NN, Györfi T, Iliopoulos D, Herlyn D, Greenstein D, Linnenbach AJ, Daly JM, Jensen P, Rodeck U, Herlyn M. Growth-factor-independence and invasive properties of colorectal carcinoma cells. Int J Cancer. 1992 Jan 21; 50(2):274-80. PMID: 1730521.
      Citations:    
    119. Bender H, Takahashi H, Adachi K, Belser P, Liang SH, Prewett M, Schrappe M, Sutter A, Rodeck U, Herlyn D. Immunotherapy of human glioma xenografts with unlabeled, 131I-, or 125I-labeled monoclonal antibody 425 to epidermal growth factor receptor. Cancer Res. 1992 Jan 1; 52(1):121-6. PMID: 1727372.
      Citations:    
    120. Adachi K, Belser P, Bender H, Li D, Rodeck U, Benveniste EN, Woo D, Schmiegel WH, Herlyn D. Enhancement of epidermal growth factor receptor expression on glioma cells by recombinant tumor necrosis factor alpha. Cancer Immunol Immunother. 1992; 34(6):370-6. PMID: 1563013.
      Citations:    
    121. Rodeck U, Melber K, Kath R, Menssen HD, Varello M, Atkinson B, Herlyn M. Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes. J Invest Dermatol. 1991 Jul; 97(1):20-6. PMID: 2056188.
      Citations:    
    122. Kath R, Jambrosic JA, Holland L, Rodeck U, Herlyn M. Development of invasive and growth factor-independent cell variants from primary human melanomas. Cancer Res. 1991 Apr 15; 51(8):2205-11. PMID: 2009539.
      Citations:    
    123. Valyi-Nagy I, Rodeck U, Kath R, Mancianti ML, Clark WH, Herlyn M. The human melanocyte system as a model for studies on tumor progression. Basic Life Sci. 1991; 57:315-26; discussion 326-8. PMID: 1814292.
      Citations:    
    124. Murthy U, Rieman DJ, Rodeck U. Inhibition of TGF alpha-induced second messengers by anti-EGF receptor antibody-425. Biochem Biophys Res Commun. 1990 Oct 30; 172(2):471-6. PMID: 2241946.
      Citations:    
    125. Rodeck U, Williams N, Murthy U, Herlyn M. Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha. J Cell Biochem. 1990 Oct; 44(2):69-79. PMID: 2250044.
      Citations:    
    126. Szala S, Kasai Y, Steplewski Z, Rodeck U, Koprowski H, Linnenbach AJ. Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens. Proc Natl Acad Sci U S A. 1990 Sep; 87(17):6833-7. PMID: 2395876.
      Citations:    
    127. Kath R, Rodeck U, Menssen HD, Mancianti ML, Linnenbach AJ, Elder DE, Herlyn M. Tumor progression in the human melanocytic system. Anticancer Res. 1989 Jul-Aug; 9(4):865-72. PMID: 2554787.
      Citations:    
    128. Iliopoulos D, Ernst C, Steplewski Z, Jambrosic JA, Rodeck U, Herlyn M, Clark WH, Koprowski H, Herlyn D. Inhibition of metastases of a human melanoma xenograft by monoclonal antibody to the GD2/GD3 gangliosides. J Natl Cancer Inst. 1989 Mar 15; 81(6):440-4. PMID: 2918552.
      Citations:    
    129. Rakowicz-Szulczynska EM, Otwiaska D, Rodeck U, Koprowski H. Epidermal growth factor (EGF) and monoclonal antibody to cell surface EGF receptor bind to the same chromatin receptor. Arch Biochem Biophys. 1989 Feb 1; 268(2):456-64. PMID: 2783644.
      Citations:    
    130. Mancianti ML, Herlyn M, Weil D, Jambrosic J, Rodeck U, Becker D, Diamond L, Clark WH, Koprowski H. Growth and phenotypic characteristics of human nevus cells in culture. J Invest Dermatol. 1988 Feb; 90(2):134-41. PMID: 2828480.
      Citations:    
    131. Rodeck U, Herlyn M, Herlyn D, Molthoff C, Atkinson B, Varello M, Steplewski Z, Koprowski H. Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects. Cancer Res. 1987 Jul 15; 47(14):3692-6. PMID: 3297307.
      Citations:    
    132. Takahashi H, Herlyn D, Atkinson B, Powe J, Rodeck U, Alavi A, Bruce DA, Koprowski H. Radioimmunodetection of human glioma xenografts by monoclonal antibody to epidermal growth factor receptor. Cancer Res. 1987 Jul 15; 47(14):3847-50. PMID: 3594441.
      Citations:    
    133. Basu A, Murthy U, Rodeck U, Herlyn M, Mattes L, Das M. Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas. Cancer Res. 1987 May 15; 47(10):2531-6. PMID: 2436750.
      Citations:    
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