Anshul Bhardwaj

TitleAssoc Prof CHP
InstitutionThomas Jefferson University
DepartmentNursing - Undergraduate
Address233 S. 10th Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Komolov KE, Sulon SM, Bhardwaj A, van Keulen SC, Duc NM, Laurinavichyute DK, Lou HJ, Turk BE, Chung KY, Dror RO, Benovic JL. Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Mol Cell. 2020 Dec 09. PMID: 33321095.
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    2. Yoo SM, Bhardwaj A, Benovic JL. Arresting Developments in Biased Signaling. Trends Pharmacol Sci. 2020 Apr 30. PMID: 32362341.
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    3. Thangavel C, Boopathi E, Liu Y, McNair C, Haber A, Perepelyuk M, Bhardwaj A, Addya S, Ertel A, Shoyele S, Birbe R, Salvino JM, Dicker AP, Knudsen KE, Den RB. Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer. Clin Cancer Res. 2018 Mar 15; 24(6):1402-1414. PMID: 29311118.
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    4. Khasnis MD, Halkidis K, Bhardwaj A, Root MJ. Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer. PLoS Pathog. 2016 Dec; 12(12):e1006098. PMID: 27992602.
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    5. Thangavel C, Boopathi E, Liu Y, Haber A, Ertel A, Bhardwaj A, Addya S, Williams N, Ciment S, Cotzia P, Dean JL, Snook AE, McNair C, Price MA, Hernandez JR, Zhao SG, Birbe R, McCarthy JB, Turely EA, Pienta KJ, Feng FY, Dicker AP, Knudsen KE, Den RB. RB loss promotes prostate cancer metastasis. Cancer Res. 2016 Dec 06. PMID: 27923835.
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    6. Bhardwaj A, Sankhala RS, Olia AS, Brooke D, Casjens SR, Taylor DJ, Prevelige PE, Cingolani G. Structural Plasticity of the Protein Plug That Traps Newly Packaged Genomes in Podoviridae Virions. J Biol Chem. 2016 Jan 1; 291(1):215-26. PMID: 26574546.
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    7. Lokareddy RK, Hapsari RA, van Rheenen M, Pumroy RA, Bhardwaj A, Steen A, Veenhoff LM, Cingolani G. Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure. 2015 Jul 7; 23(7):1305-16. PMID: 26051712.
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    8. Komolov KE, Bhardwaj A, Benovic JL. Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases. J Biol Chem. 2015 Aug 21; 290(34):20629-47. PMID: 26032409.
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    9. Ronzone E, Wesolowski J, Bauler LD, Bhardwaj A, Hackstadt T, Paumet F. An a-Helical Core Encodes the Dual Functions of the Chlamydial Protein IncA. J Biol Chem. 2014 Nov 28; 289(48):33469-80. PMID: 25324548.
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    10. Bhardwaj A, Casjens SR, Cingolani G. Exploring the atomic structure and conformational flexibility of a 320 Ă… long engineered viral fiber using X-ray crystallography. Acta Crystallogr D Biol Crystallogr. 2014 Feb; 70(Pt 2):342-53. PMID: 24531468.
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    11. Bhardwaj A, Olia AS, Cingolani G. Architecture of viral genome-delivery molecular machines. Curr Opin Struct Biol. 2014 Apr; 25C:1-8. PMID: 24878339.
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    12. Leavitt JC, Gogokhia L, Gilcrease EB, Bhardwaj A, Cingolani G, Casjens SR. The tip of the tail needle affects the rate of DNA delivery by bacteriophage p22. PLoS One. 2013; 8(8):e70936. PMID: 23951045.
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    13. Fertala J, Steplewski A, Kostas J, Beredjiklian P, Williams G, Arnold W, Abboud J, Bhardwaj A, Hou C, Fertala A. Engineering and Characterization of the Chimeric Antibody That Targets the C-terminal Telopeptide of the a2 Chain of Human Collagen I: A Next Step in the Quest to Reduce Localized Fibrosis. Connect Tissue Res. 2013; 54(3):187-96. PMID: 23586407.
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    14. Lokareddy RK, Bhardwaj A, Cingolani G. Atomic Structure of Dual-Specificity Phosphatase 26, a Novel p53 Phosphatase. Biochemistry. 2013 Feb 5; 52(5):938-48. PMID: 23298255.
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    15. Roy A, Bhardwaj A, Datta P, Lander GC, Cingolani G. Small terminase couples viral DNA binding to genome-packaging ATPase activity. Structure. 2012 Aug 8; 20(8):1403-13. PMID: 22771211.
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    16. Bhardwaj A, Molineux IJ, Casjens SR, Cingolani G. Atomic structure of bacteriophage Sf6 tail needle knob. J Biol Chem. 2011 Sep 2; 286(35):30867-77. PMID: 21705802.
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    17. Lott K, Bhardwaj A, Sims PJ, Cingolani G. A minimal nuclear localization signal (NLS) in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin alpha1. J Biol Chem. 2011 Aug 12; 286(32):28160-9. PMID: 21690087.
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    18. Roy A, Bhardwaj A, Cingolani G. Crystallization of the nonameric small terminase subunit of bacteriophage P22. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jan 1; 67(Pt 1):104-10. PMID: 21206037.
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    19. Bhardwaj A, Cingolani G. Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta. Biochemistry. 2010 Jun 22; 49(24):5042-7. PMID: 20476751.
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    20. Lott K, Bhardwaj A, Mitrousis G, Pante N, Cingolani G. The importin beta binding domain modulates the avidity of importin beta for the nuclear pore complex. J Biol Chem. 2010 Apr 30; 285(18):13769-80. PMID: 20197273.
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    21. Bhardwaj A, Walker-Kopp N, Casjens SR, Cingolani G. An evolutionarily conserved family of virion tail needles related to bacteriophage P22 gp26: correlation between structural stability and length of the alpha-helical trimeric coiled coil. J Mol Biol. 2009 Aug 7; 391(1):227-45. PMID: 19482036.
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    22. Bhardwaj A, Walker-Kopp N, Wilkens S, Cingolani G. Foldon-guided self-assembly of ultra-stable protein fibers. Protein Sci. 2008 Sep; 17(9):1475-85. PMID: 18535304.
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    23. Olia AS, Bhardwaj A, Joss L, Casjens S, Cingolani G. Role of gene 10 protein in the hierarchical assembly of the bacteriophage P22 portal vertex structure. Biochemistry. 2007 Jul 31; 46(30):8776-84. PMID: 17620013.
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    24. Bhardwaj A, Olia AS, Walker-Kopp N, Cingolani G. Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22. J Mol Biol. 2007 Aug 10; 371(2):374-87. PMID: 17574574.
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    25. Bhardwaj A, Welfle K, Misselwitz R, Ayora S, Alonso JC, Welfle H. Conformation and stability of the Streptococcus pyogenes pSM19035-encoded site-specific beta recombinase, and identification of a folding intermediate. Biol Chem. 2006 May; 387(5):525-33. PMID: 16740123.
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