Bruno Calabretta

TitleProfessor
InstitutionThomas Jefferson University
DepartmentCancer Biology
Address233 S. 10th Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Porazzi P, Petruk S, Pagliaroli L, De Dominici M, Deming D, Puccetti MV, Kushinsky S, Kumar G, Minieri V, Barbieri E, Deliard S, Grande A, Trizzino M, Gardini A, Canaani E, Palmisiano N, Porcu P, Ertel A, Fortina P, Eischen CM, Mazo A, Calabretta B. Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression. Cancer Res. 2022 02 01; 82(3):458-471. PMID: 34903608.
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    2. Pagliaroli L, Porazzi P, Curtis AT, Scopa C, Mikkers HMM, Freund C, Daxinger L, Deliard S, Welsh SA, Offley S, Ott CA, Calabretta B, Brugmann SA, Santen GWE, Trizzino M. Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders. Nat Commun. 2021 11 09; 12(1):6469. PMID: 34753942.
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    3. Porazzi P, De Dominici M, Salvino J, Calabretta B. Targeting the CDK6 Dependence of Ph+ Acute Lymphoblastic Leukemia. Genes (Basel). 2021 Aug 29; 12(9). PMID: 34573335.
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    4. Silvestri G, Trotta R, Stramucci L, Ellis JJ, Harb JG, Neviani P, Wang S, Eisfeld AK, Walker CJ, Zhang B, Srutova K, Gambacorti-Passerini C, Pineda G, Jamieson CHM, Stagno F, Vigneri P, Nteliopoulos G, May PC, Reid AG, Garzon R, Roy DC, Moutuou MM, Guimond M, Hokland P, Deininger MW, Fitzgerald G, Harman C, Dazzi F, Milojkovic D, Apperley JF, Marcucci G, Qi J, Polakova KM, Zou Y, Fan X, Baer MR, Calabretta B, Perrotti D. Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions. Blood Cancer Discov. 2020 Jul; 1(1):48-67. PMID: 32974613.
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    5. De Dominici M, Porazzi P, Xiao Y, Chao A, Tang HY, Kumar G, Fortina P, Spinelli O, Rambaldi A, Peterson LF, Petruk S, Barletta C, Mazo A, Cingolani G, Salvino JM, Calabretta B. Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and independent effects by CDK6-specific PROTACs. Blood. 2020 Feb 07. PMID: 32040545.
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    6. Minieri V, De Dominici M, Nevalainen MT, Calabretta B. Targeting the STAT5 pathway in Ph+ acute lymphoblastic leukemia. Oncotarget. 2018 Dec 04; 9(95):36726-36727. PMID: 30613358.
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    7. D'Aguanno S, Valentini E, Tupone MG, Desideri M, Di Martile M, Spagnuolo M, Buglioni S, Ercolani C, Falcone I, De Dominici M, Milella M, Rizzo MG, Calabretta B, Cota C, Anichini A, Trisciuoglio D, Del Bufalo D. Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb. J Exp Clin Cancer Res. 2018 Nov 19; 37(1):278. PMID: 30454024.
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    8. Minieri V, De Dominici M, Porazzi P, Mariani SA, Spinelli O, Rambaldi A, Peterson LF, Porcu P, Nevalainen MT, Calabretta B. Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia. Cancer Res. 2018 Oct 15; 78(20):5793-5807. PMID: 30154155.
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    9. Spagnuolo M, Regazzo G, De Dominici M, Sacconi A, Pelosi A, Korita E, Marchesi F, Pisani F, Magenta A, Lulli V, Cordone I, Mengarelli A, Strano S, Blandino G, Rizzo MG, Calabretta B. Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. Haematologica. 2018 Aug 03. PMID: 30076175.
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    10. Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A. Targeted Enhancer Activation by a Subunit of the Integrator Complex. Mol Cell. 2018 Jul 05; 71(1):103-116.e7. PMID: 30008316.
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    11. Parenti S, Montorsi L, Fantini S, Mammoli F, Gemelli C, Atene CG, Losi L, Frassineti C, Calabretta B, Tagliafico E, Ferrari S, Zanocco-Marani T, Grande A. KLF4 mediates the effect of 5-ASA on the ß-catenin pathway in colon cancer cells. Cancer Prev Res (Phila). 2018 May 24. PMID: 29794245.
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    12. De Dominici M, Porazzi P, Soliera AR, Mariani SA, Addya S, Fortina P, Peterson LF, Spinelli O, Rambaldi A, Martinelli G, Ferrari A, Iacobucci I, Calabretta B. Targeting CDK6 and BCL2 Exploits the "MYB Addiction" of Ph+ Acute Lymphoblastic Leukemia. Cancer Res. 2018 Feb 15; 78(4):1097-1109. PMID: 29233926.
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    13. Mitchell R, Hopcroft LEM, Baquero P, Allan EK, Hewit K, James D, Hamilton G, Mukhopadhyay A, O'Prey J, Hair A, Melo JV, Chan E, Ryan KM, Maguer-Satta V, Druker BJ, Clark RE, Mitra S, Herzyk P, Nicolini FE, Salomoni P, Shanks E, Calabretta B, Holyoake TL, Helgason GV. Targeting BCR-ABL-Independent TKI Resistance in Chronic Myeloid Leukemia by mTOR and Autophagy Inhibition. J Natl Cancer Inst. 2017 Nov 20. PMID: 29165716.
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    14. Petruk S, Cai J, Sussman R, Sun G, Kovermann SK, Mariani SA, Calabretta B, McMahon SB, Brock HW, Iacovitti L, Mazo A. Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation. Mol Cell. 2017 Apr 20; 66(2):247-257.e5. PMID: 28410996.
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    15. Petruk S, Mariani SA, De Dominici M, Porazzi P, Minieri V, Cai J, Iacovitti L, Flomenberg N, Calabretta B, Mazo A. Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification. Cell Rep. 2017 Apr 11; 19(2):295-306. PMID: 28402853.
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    16. Riva B, De Dominici M, Gnemmi I, Mariani SA, Minassi A, Minieri V, Salomoni P, Canonico PL, Genazzani AA, Calabretta B, Condorelli F. Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of ß-catenin and mTORC1/2. Oncotarget. 2016 Dec 06; 7(49):81555-81570. PMID: 27835591.
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    17. Montorsi L, Parenti S, Losi L, Ferrarini F, Gemelli C, Rossi A, Manco G, Ferrari S, Calabretta B, Tagliafico E, Zanocco-Marani T, Grande A. Expression of µ-protocadherin is negatively regulated by the activation of the ß-catenin signaling pathway in normal and cancer colorectal enterocytes. Cell Death Dis. 2016; 7:e2263. PMID: 27310872.
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    18. Karvela M, Baquero P, Kuntz EM, Mukhopadhyay A, Mitchell R, Allan EK, Chan E, Kranc KR, Calabretta B, Salomoni P, Gottlieb E, Holyoake TL, Helgason GV. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016 Jun 2; 12(6):936-48. PMID: 27168493.
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    19. Mariani SA, Minieri V, De Dominici M, Iacobucci I, Peterson LF, Calabretta B. CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia. Leukemia. 2016 Aug; 30(8):1682-90. PMID: 27125204.
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    20. Manzotti G, Parenti S, Ferrari-Amorotti G, Soliera AR, Cattelani S, Montanari M, Cavalli D, Ertel A, Grande A, Calabretta B. Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database. Cell Cycle. 2015 Aug 18; 14(16):2578-89. PMID: 26102293.
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    21. Liao Z, Gu L, Vergalli J, Mariani SA, De Dominici M, Lokareddy RK, Dagvadorj A, Purushottamachar P, McCue PA, Trabulsi E, Lallas CD, Gupta S, Ellsworth E, Blackmon S, Ertel A, Fortina P, Leiby B, Xia G, Rui H, Hoang DT, Gomella LG, Cingolani G, Njar V, Pattabiraman N, Calabretta B, Nevalainen MT. Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia. Mol Cancer Ther. 2015 Aug; 14(8):1777-93. PMID: 26026053.
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    22. Ferrari-Amorotti G, Chiodoni C, Shen F, Cattelani S, Soliera AR, Manzotti G, Grisendi G, Dominici M, Rivasi F, Colombo MP, Fatatis A, Calabretta B. Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity. Neoplasia. 2014 Dec; 16(12):1047-58. PMID: 25499218.
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    23. Helgason GV, Mukhopadhyay A, Karvela M, Salomoni P, Calabretta B, Holyoake TL. Autophagy in chronic myeloid leukaemia: stem cell survival and implication in therapy. Curr Cancer Drug Targets. 2013 Sep; 13(7):724-34. PMID: 23941517.
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    24. Mariani SA, Calabretta B. Leukemia stem cells: Old concepts and new perspectives. Mol Aspects Med. 2014 Oct; 39:102-9. PMID: 23820118.
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    25. Ferrari-Amorotti G, Fragliasso V, Esteki R, Prudente Z, Soliera AR, Cattelani S, Manzotti G, Grisendi G, Dominici M, Pieraccioli M, Raschellà G, Chiodoni C, Colombo MP, Calabretta B. Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion. Cancer Res. 2013 Jan 1; 73(1):235-45. PMID: 23054398.
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    26. Pelosi A, Careccia S, Lulli V, Romania P, Marziali G, Testa U, Lavorgna S, Lo-Coco F, Petti MC, Calabretta B, Levrero M, Piaggio G, Rizzo MG. miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia. Oncogene. 2013 Aug 1; 32(31):3648-54. PMID: 22964640.
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    27. Cattelani S, Ferrari-Amorotti G, Galavotti S, Defferrari R, Tanno B, Cialfi S, Vergalli J, Fragliasso V, Guerzoni C, Manzotti G, Soliera AR, Menin C, Bertorelle R, McDowell HP, Inserra A, Belli ML, Varesio L, Tweddle D, Tonini GP, Altavista P, Dominici C, Raschellà G, Calabretta B. The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform. Neoplasia. 2012 Jul; 14(7):634-43. PMID: 22904680.
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    28. Manzotti G, Mariani SA, Corradini F, Bussolari R, Cesi V, Vergalli J, Ferrari-Amorotti G, Fragliasso V, Soliera AR, Cattelani S, Raschellà G, Holyoake TL, Calabretta B. Expression of p89(c-Mybex9b), an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells. Blood Cancer J. 2012 May; 2(5):e71. PMID: 22829973.
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    29. Fragliasso V, Chiodo Y, Ferrari-Amorotti G, Soliera AR, Manzotti G, Cattelani S, Candini O, Grisendi G, Vergalli J, Mariani SA, Guerzoni C, Calabretta B. Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPa in K562 cells. J Cell Biochem. 2012 May; 113(5):1704-13. PMID: 22212957.
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    30. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
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    31. Soliera AR, Mariani SA, Audia A, Lidonnici MR, Addya S, Ferrari-Amorotti G, Cattelani S, Manzotti G, Fragliasso V, Peterson L, Perini G, Holyoake TL, Calabretta B. Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1. Leukemia. 2012 Jul; 26(7):1555-63. PMID: 22285998.
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    32. Calabretta B, Salomoni P. Suppression of autophagy by BCR/ABL. Front Biosci (Schol Ed). 2012; 4:453-60. PMID: 22202070.
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    33. Cesi V, Casciati A, Sesti F, Tanno B, Calabretta B, Raschellà G. TGFß-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells. Cell Cycle. 2011 Dec 1; 10(23):4149-61. PMID: 22101269.
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    34. Waldron T, De Dominici M, Soliera AR, Audia A, Iacobucci I, Lonetti A, Martinelli G, Zhang Y, Martinez R, Hyslop T, Bender TP, Calabretta B. c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells. Leukemia. 2012 Apr; 26(4):644-53. PMID: 21960247.
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    35. Calabretta B, Salomoni P. Inhibition of autophagy: a new strategy to enhance sensitivity of chronic myeloid leukemia stem cells to tyrosine kinase inhibitors. Leuk Lymphoma. 2011 Feb; 52 Suppl 1:54-9. PMID: 21250825.
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    36. La Rocca G, Shi B, Audia A, Ferrari-Amorotti G, Mellert HS, Calabretta B, McMahon SB, Sepp-Lorenzino L, Baserga R. Regulation of microRNA-145 by growth arrest and differentiation. Exp Cell Res. 2011 Feb 15; 317(4):488-95. PMID: 21111732.
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    37. Lidonnici MR, Audia A, Soliera AR, Prisco M, Ferrari-Amorotti G, Waldron T, Donato N, Zhang Y, Martinez RV, Holyoake TL, Calabretta B. Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells. Cancer Res. 2010 Oct 15; 70(20):7949-59. PMID: 20924107.
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    38. Ferrari-Amorotti G, Mariani SA, Novi C, Cattelani S, Pecorari L, Corradini F, Soliera AR, Manzotti G, Fragliasso V, Zhang Y, Martinez RV, Lam EW, Guerzoni C, Calabretta B. The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain. J Biol Chem. 2010 Oct 1; 285(40):30837-50. PMID: 20659895.
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    39. Tanno B, Sesti F, Cesi V, Bossi G, Ferrari-Amorotti G, Bussolari R, Tirindelli D, Calabretta B, Raschellà G. Expression of Slug is regulated by c-Myb and is required for invasion and bone marrow homing of cancer cells of different origin. J Biol Chem. 2010 Sep 17; 285(38):29434-45. PMID: 20622260.
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    40. Vitali R, Mancini C, Cesi V, Tanno B, Piscitelli M, Mancuso M, Sesti F, Pasquali E, Calabretta B, Dominici C, Raschellà G. Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. Int J Cancer. 2009 Dec 1; 125(11):2547-55. PMID: 19623650.
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    41. Salomoni P, Calabretta B. Targeted therapies and autophagy: new insights from chronic myeloid leukemia. Autophagy. 2009 Oct; 5(7):1050-1. PMID: 19713759.
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    42. Pecorari L, Marin O, Silvestri C, Candini O, Rossi E, Guerzoni C, Cattelani S, Mariani SA, Corradini F, Ferrari-Amorotti G, Cortesi L, Bussolari R, Raschellà G, Federico MR, Calabretta B. Elongation Factor 1 alpha interacts with phospho-Akt in breast cancer cells and regulates their proliferation, survival and motility. Mol Cancer. 2009; 8:58. PMID: 19646290.
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    43. Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, Galavotti S, Young KW, Selmi T, Yacobi R, Van Etten RA, Donato N, Hunter A, Dinsdale D, Tirrò E, Vigneri P, Nicotera P, Dyer MJ, Holyoake T, Salomoni P, Calabretta B. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest. 2009 May; 119(5):1109-23. PMID: 19363292.
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    44. Vitali R, Mancini C, Cesi V, Tanno B, Mancuso M, Bossi G, Zhang Y, Martinez RV, Calabretta B, Dominici C, Raschellà G. Slug (SNAI2) down-regulation by RNA interference facilitates apoptosis and inhibits invasive growth in neuroblastoma preclinical models. Clin Cancer Res. 2008 Jul 15; 14(14):4622-30. PMID: 18628477.
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    45. Soliera AR, Lidonnici MR, Ferrari-Amorotti G, Prisco M, Zhang Y, Martinez RV, Donato NJ, Calabretta B. Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells. Blood. 2008 Sep 1; 112(5):1942-50. PMID: 18550858.
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    46. Cattelani S, Defferrari R, Marsilio S, Bussolari R, Candini O, Corradini F, Ferrari-Amorotti G, Guerzoni C, Pecorari L, Menin C, Bertorelle R, Altavista P, McDowell HP, Boldrini R, Dominici C, Tonini GP, Raschellà G, Calabretta B. Impact of a single nucleotide polymorphism in the MDM2 gene on neuroblastoma development and aggressiveness: results of a pilot study on 239 patients. Clin Cancer Res. 2008 Jun 1; 14(11):3248-53. PMID: 18519749.
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    47. Lidonnici MR, Corradini F, Waldron T, Bender TP, Calabretta B. Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis. Blood. 2008 May 1; 111(9):4771-9. PMID: 18227349.
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    48. Vitali R, Cesi V, Tanno B, Ferrari-Amorotti G, Dominici C, Calabretta B, Raschellà G. Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide. Biochem Biophys Res Commun. 2008 Apr 4; 368(2):350-6. PMID: 18230339.
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    49. Schwab R, Bussolari R, Corvetta D, Chayka O, Santilli G, Kwok JM, Ferrari-Amorotti G, Amorotti GF, Tonini GP, Iacoviello L, Bertorelle R, Menin C, Hubank M, Calabretta B, Sala A. Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk. Oncogene. 2008 May 1; 27(20):2929-33. PMID: 18026132.
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    50. Corradini F, Bussolari R, Cerioli D, Lidonnici MR, Calabretta B. A degradation-resistant c-Myb mutant cooperates with Bcl-2 in enhancing proliferative potential and survival of hematopoietic cells. Blood Cells Mol Dis. 2007 Nov-Dec; 39(3):292-6. PMID: 17644012.
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    51. Chang JS, Santhanam R, Trotta R, Neviani P, Eiring AM, Briercheck E, Ronchetti M, Roy DC, Calabretta B, Caligiuri MA, Perrotti D. High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation. Blood. 2007 Aug 1; 110(3):994-1003. PMID: 17475908.
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    52. Liu M, Tu X, Ferrari-Amorotti G, Calabretta B, Baserga R. Downregulation of the upstream binding factor1 by glycogen synthase kinase3beta in myeloid cells induced to differentiate. J Cell Biochem. 2007 Apr 1; 100(5):1154-69. PMID: 17063482.
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    53. Iotti G, Ferrari-Amorotti G, Rosafio C, Corradini F, Lidonnici MR, Ronchetti M, Bardini M, Zhang Y, Martinez R, Blasi F, Calabretta B. Expression of CCL9/MIP-1gamma is repressed by BCR/ABL and its restoration suppresses in vivo leukemogenesis of 32D-BCR/ABL cells. Oncogene. 2007 May 24; 26(24):3482-91. PMID: 17160016.
      Citations:    
    54. Bussolari R, Candini O, Colomer D, Corradini F, Guerzoni C, Mariani SA, Cattelani S, Silvestri C, Pecorari L, Iacobucci I, Soverini S, Fasano T, Martinelli G, Cervantes F, Calabretta B. Coding sequence and intron-exon junctions of the c-myb gene are intact in the chronic phase and blast crisis stages of chronic myeloid leukemia patients. Leuk Res. 2007 Feb; 31(2):163-7. PMID: 16797705.
      Citations:    
    55. Guerzoni C, Ferrari-Amorotti G, Bardini M, Mariani SA, Calabretta B. Effects of C/EBPalpha and C/EBPbeta in BCR/ABL-expressing cells: differences and similarities. Cell Cycle. 2006 Jun; 5(12):1254-7. PMID: 16760662.
      Citations:    
    56. Ferrari-Amorotti G, Keeshan K, Zattoni M, Guerzoni C, Iotti G, Cattelani S, Donato NJ, Calabretta B. Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha. Blood. 2006 Aug 15; 108(4):1353-62. PMID: 16670262.
      Citations:    
    57. Guerzoni C, Bardini M, Mariani SA, Ferrari-Amorotti G, Neviani P, Panno ML, Zhang Y, Martinez R, Perrotti D, Calabretta B. Inducible activation of CEBPB, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells. Blood. 2006 May 15; 107(10):4080-9. PMID: 16418324.
      Citations:    
    58. Corradini F, Cesi V, Bartella V, Pani E, Bussolari R, Candini O, Calabretta B. Enhanced proliferative potential of hematopoietic cells expressing degradation-resistant c-Myb mutants. J Biol Chem. 2005 Aug 26; 280(34):30254-62. PMID: 15927960.
      Citations:    
    59. Tanno B, Cesi V, Vitali R, Sesti F, Giuffrida ML, Mancini C, Calabretta B, Raschellà G. Silencing of endogenous IGFBP-5 by micro RNA interference affects proliferation, apoptosis and differentiation of neuroblastoma cells. Cell Death Differ. 2005 Mar; 12(3):213-23. PMID: 15618969.
      Citations:    
    60. Cesi V, Giuffrida ML, Vitali R, Tanno B, Mancini C, Calabretta B, Raschellà G. C/EBP alpha and beta mimic retinoic acid activation of IGFBP-5 in neuroblastoma cells by a mechanism independent from binding to their site. Exp Cell Res. 2005 Apr 15; 305(1):179-89. PMID: 15777798.
      Citations:    
    61. Prisco M, Maiorana A, Guerzoni C, Calin G, Calabretta B, Voit R, Grummt I, Baserga R. Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells. Mol Cell Biol. 2004 Jun; 24(12):5421-33. PMID: 15169904.
      Citations:    
    62. Perrotti D, Calabretta B. Translational regulation by the p210 BCR/ABL oncoprotein. Oncogene. 2004 Apr 19; 23(18):3222-9. PMID: 15094772.
      Citations:    
    63. Calabretta B, Perrotti D. The biology of CML blast crisis. Blood. 2004 Jun 1; 103(11):4010-22. PMID: 14982876.
      Citations:    
    64. Perrotti D, Trotta R, Calabretta B. Altered mRNA translation: possible mechanism for CML disease progression. Cell Cycle. 2003 May-Jun; 2(3):177-80. PMID: 12734417.
      Citations:    
    65. Keeshan K, Santilli G, Corradini F, Perrotti D, Calabretta B. Transcription activation function of C/EBPalpha is required for induction of granulocytic differentiation. Blood. 2003 Aug 15; 102(4):1267-75. PMID: 12702500.
      Citations:    
    66. Trotta R, Vignudelli T, Candini O, Intine RV, Pecorari L, Guerzoni C, Santilli G, Byrom MW, Goldoni S, Ford LP, Caligiuri MA, Maraia RJ, Perrotti D, Calabretta B. BCR/ABL activates mdm2 mRNA translation via the La antigen. Cancer Cell. 2003 Feb; 3(2):145-60. PMID: 12620409.
      Citations:    
    67. Perrotti D, Calabretta B. Post-transcriptional mechanisms in BCR/ABL leukemogenesis: role of shuttling RNA-binding proteins. Oncogene. 2002 Dec 9; 21(56):8577-83. PMID: 12476304.
      Citations:    
    68. Cesi V, Tanno B, Vitali R, Mancini C, Giuffrida ML, Calabretta B, Raschellà G. Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation. Cell Death Differ. 2002 Nov; 9(11):1232-9. PMID: 12404122.
      Citations:    
    69. Rosen K, Shi W, Calabretta B, Filmus J. Cell detachment triggers p38 mitogen-activated protein kinase-dependent overexpression of Fas ligand. A novel mechanism of Anoikis of intestinal epithelial cells. J Biol Chem. 2002 Nov 29; 277(48):46123-30. PMID: 12356751.
      Citations:    
    70. Tanno B, Negroni A, Vitali R, Pirozzoli MC, Cesi V, Mancini C, Calabretta B, Raschellà G. Expression of insulin-like growth factor-binding protein 5 in neuroblastoma cells is regulated at the transcriptional level by c-Myb and B-Myb via direct and indirect mechanisms. J Biol Chem. 2002 Jun 28; 277(26):23172-80. PMID: 11973331.
      Citations:    
    71. Iervolino A, Santilli G, Trotta R, Guerzoni C, Cesi V, Bergamaschi A, Gambacorti-Passerini C, Calabretta B, Perrotti D. hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis. Mol Cell Biol. 2002 Apr; 22(7):2255-66. PMID: 11884611.
      Citations:    
    72. Kim BC, Mamura M, Choi KS, Calabretta B, Kim SJ. Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells. Mol Cell Biol. 2002 Mar; 22(5):1369-78. PMID: 11839804.
      Citations:    
    73. Perrotti D, Cesi V, Trotta R, Guerzoni C, Santilli G, Campbell K, Iervolino A, Condorelli F, Gambacorti-Passerini C, Caligiuri MA, Calabretta B. BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2. Nat Genet. 2002 Jan; 30(1):48-58. PMID: 11753385.
      Citations:    
    74. Powzaniuk MA, Trotta R, Loza MJ, Harth A, Iozzo RV, Eisenlohr LC, Perussia B, Calabretta B. B-Myb overexpression results in activation and increased Fas/Fas ligand-mediated cytotoxicity of T and NK cells. J Immunol. 2001 Jul 1; 167(1):242-9. PMID: 11418655.
      Citations:    
    75. Condorelli F, Salomoni P, Cotteret S, Cesi V, Srinivasula SM, Alnemri ES, Calabretta B. Caspase cleavage enhances the apoptosis-inducing effects of BAD. Mol Cell Biol. 2001 May; 21(9):3025-36. PMID: 11287608.
      Citations:    
    76. Biroccio A, Benassi B, D'Agnano I, D'Angelo C, Buglioni S, Mottolese M, Ricciotti A, Citro G, Cosimelli M, Ramsay RG, Calabretta B, Zupi G. c-Myb and Bcl-x overexpression predicts poor prognosis in colorectal cancer: clinical and experimental findings. Am J Pathol. 2001 Apr; 158(4):1289-99. PMID: 11290547.
      Citations:    
    77. Dahéron L, Zenz T, Siracusa LD, Brenner C, Calabretta B. Molecular cloning of Ian4: a BCR/ABL-induced gene that encodes an outer membrane mitochondrial protein with GTP-binding activity. Nucleic Acids Res. 2001 Mar 15; 29(6):1308-16. PMID: 11238997.
      Citations:    
    78. Amendola R, Martinez R, Negroni A, Venturelli D, Tanno B, Calabretta B, Raschellà G. DR-nm23 expression affects neuroblastoma cell differentiation, integrin expression, and adhesion characteristics. Med Pediatr Oncol. 2001 Jan; 36(1):93-6. PMID: 11464913.
      Citations:    
    79. Cirinnà M, Trotta R, Salomoni P, Kossev P, Wasik M, Perrotti D, Calabretta B. Bcl-2 expression restores the leukemogenic potential of a BCR/ABL mutant defective in transformation. Blood. 2000 Dec 1; 96(12):3915-21. PMID: 11090078.
      Citations:    
    80. Fernandes MJ, Iscove NN, Gingras G, Calabretta B. Identification and characterization of the gene for a novel C-type lectin (CLECSF7) that maps near the natural killer gene complex on human chromosome 12. Genomics. 2000 Oct 15; 69(2):263-70. PMID: 11031109.
      Citations:    
    81. Negroni A, Venturelli D, Tanno B, Amendola R, Ransac S, Cesi V, Calabretta B, Raschellà G. Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis. Cell Death Differ. 2000 Sep; 7(9):843-50. PMID: 11042679.
      Citations:    
    82. Perrotti D, Iervolino A, Cesi V, Cirinná M, Lombardini S, Grassilli E, Bonatti S, Claudio PP, Calabretta B. BCR-ABL prevents c-jun-mediated and proteasome-dependent FUS (TLS) proteolysis through a protein kinase CbetaII-dependent pathway. Mol Cell Biol. 2000 Aug; 20(16):6159-69. PMID: 10913197.
      Citations:    
    83. Salomoni P, Condorelli F, Sweeney SM, Calabretta B. Versatility of BCR/ABL-expressing leukemic cells in circumventing proapoptotic BAD effects. Blood. 2000 Jul 15; 96(2):676-84. PMID: 10887134.
      Citations:    
    84. Cervellera M, Raschella G, Santilli G, Tanno B, Ventura A, Mancini C, Sevignani C, Calabretta B, Sala A. Direct transactivation of the anti-apoptotic gene apolipoprotein J (clusterin) by B-MYB. J Biol Chem. 2000 Jul 14; 275(28):21055-60. PMID: 10770937.
      Citations:    
    85. Venturelli D, Cesi V, Ransac S, Engelhard A, Perrotti D, Calabretta B. The nucleoside diphosphate kinase activity of DRnm23 is not required for inhibition of differentiation and induction of apoptosis in 32Dcl3 myeloid precursor cells. Exp Cell Res. 2000 Jun 15; 257(2):265-71. PMID: 10837140.
      Citations:    
    86. Manzella L, Gualdi R, Perrotti D, Nicolaides NC, Girlando G, Giuffrida MA, Messina A, Calabretta B. The interferon regulatory factors 1 and 2 bind to a segment of the human c-myb first intron: possible role in the regulation of c-myb expression. Exp Cell Res. 2000 Apr 10; 256(1):248-56. PMID: 10739671.
      Citations:    
    87. Pagnan G, Stuart DD, Pastorino F, Raffaghello L, Montaldo PG, Allen TM, Calabretta B, Ponzoni M. Delivery of c-myb antisense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD(2)-targeted immunoliposomes: antitumor effects. J Natl Cancer Inst. 2000 Feb 2; 92(3):253-61. PMID: 10655443.
      Citations:    
    88. De Falco G, Bagella L, Claudio PP, De Luca A, Fu Y, Calabretta B, Sala A, Giordano A. Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation. Oncogene. 2000 Jan 20; 19(3):373-9. PMID: 10656684.
      Citations:    
    89. Engelhard A, Campbell K, Calabretta B. B-myb alters the response of myeloid precursor cells to G-CSF. Exp Cell Res. 2000 Jan 10; 254(1):153-62. PMID: 10623475.
      Citations:    
    90. Sevignani C, Cranston A, Iozzo RV, Fishel R, Calabretta B. Spontaneous and mutagen-induced transformation of primary cultures of Msh2-/- p53-/- colonocytes. Cancer Res. 1999 Dec 1; 59(23):5882-6. PMID: 10606228.
      Citations:    
    91. Peruzzi F, Prisco M, Dews M, Salomoni P, Grassilli E, Romano G, Calabretta B, Baserga R. Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis. Mol Cell Biol. 1999 Oct; 19(10):7203-15. PMID: 10490655.
      Citations:    
    92. Raschellà G, Cesi V, Amendola R, Negroni A, Tanno B, Altavista P, Tonini GP, De Bernardi B, Calabretta B. Expression of B-myb in neuroblastoma tumors is a poor prognostic factor independent from MYCN amplification. Cancer Res. 1999 Jul 15; 59(14):3365-8. PMID: 10416595.
      Citations:    
    93. Majewski M, Nieborowska-Skorska M, Salomoni P, Slupianek A, Reiss K, Trotta R, Calabretta B, Skorski T. Activation of mitochondrial Raf-1 is involved in the antiapoptotic effects of Akt. Cancer Res. 1999 Jun 15; 59(12):2815-9. PMID: 10383138.
      Citations:    
    94. Fernandes MJ, Finnegan AA, Siracusa LD, Brenner C, Iscove NN, Calabretta B. Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells. Cancer Res. 1999 Jun 1; 59(11):2709-17. PMID: 10363996.
      Citations:    
    95. Grassilli E, Salomoni P, Perrotti D, Franceschi C, Calabretta B. Resistance to apoptosis in CTLL-2 cells overexpressing B-Myb is associated with B-Myb-dependent bcl-2 induction. Cancer Res. 1999 May 15; 59(10):2451-6. PMID: 10344757.
      Citations:    
    96. Nieborowska-Skorska M, Wasik MA, Slupianek A, Salomoni P, Kitamura T, Calabretta B, Skorski T. Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis. J Exp Med. 1999 Apr 19; 189(8):1229-42. PMID: 10209040.
      Citations:    
    97. Iozzo RV, Chakrani F, Perrotti D, McQuillan DJ, Skorski T, Calabretta B, Eichstetter I. Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):3092-7. PMID: 10077642.
      Citations:    
    98. Skorski T, Wlodarski P, Daheron L, Salomoni P, Nieborowska-Skorska M, Majewski M, Wasik M, Calabretta B. BCR/ABL-mediated leukemogenesis requires the activity of the small GTP-binding protein Rac. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11858-62. PMID: 9751755.
      Citations:    
    99. Perrotti D, Bonatti S, Trotta R, Martinez R, Skorski T, Salomoni P, Grassilli E, Lozzo RV, Cooper DR, Calabretta B. TLS/FUS, a pro-oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL-mediated leukemogenesis. EMBO J. 1998 Aug 3; 17(15):4442-55. PMID: 9687511.
      Citations:    
    100. Salomoni P, Wasik MA, Riedel RF, Reiss K, Choi JK, Skorski T, Calabretta B. Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant. J Exp Med. 1998 Jun 15; 187(12):1995-2007. PMID: 9625759.
      Citations:    
    101. de Fabritiis P, Petti MC, Montefusco E, De Propris MS, Sala R, Bellucci R, Mancini M, Lisci A, Bonetto F, Geiser T, Calabretta B, Mandelli F. BCR-ABL antisense oligodeoxynucleotide in vitro purging and autologous bone marrow transplantation for patients with chronic myelogenous leukemia in advanced phase. Blood. 1998 May 1; 91(9):3156-62. PMID: 9558370.
      Citations:    
    102. Raschellà G, Tanno B, Bonetto F, Negroni A, Claudio PP, Baldi A, Amendola R, Calabretta B, Giordano A, Paggi MG. The RB-related gene Rb2/p130 in neuroblastoma differentiation and in B-myb promoter down-regulation. Cell Death Differ. 1998 May; 5(5):401-7. PMID: 10200489.
      Citations:    
    103. Wlodarski P, Wasik M, Ratajczak MZ, Sevignani C, Hoser G, Kawiak J, Gewirtz AM, Calabretta B, Skorski T. Role of p53 in hematopoietic recovery after cytotoxic treatment. Blood. 1998 Apr 15; 91(8):2998-3006. PMID: 9531612.
      Citations:    
    104. Sevignani C, Wlodarski P, Kirillova J, Mercer WE, Danielson KG, Iozzo RV, Calabretta B. Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene. J Clin Invest. 1998 Apr 15; 101(8):1572-80. PMID: 9541486.
      Citations:    
    105. Ratajczak MZ, Perrotti D, Melotti P, Powzaniuk M, Calabretta B, Onodera K, Kregenow DA, Machalinski B, Gewirtz AM. Myb and ets proteins are candidate regulators of c-kit expression in human hematopoietic cells. Blood. 1998 Mar 15; 91(6):1934-46. PMID: 9490676.
      Citations:    
    106. Skorski T, Nieborowska-Skorska M, Wlodarski P, Wasik M, Trotta R, Kanakaraj P, Salomoni P, Antonyak M, Martinez R, Majewski M, Wong A, Perussia B, Calabretta B. The SH3 domain contributes to BCR/ABL-dependent leukemogenesis in vivo: role in adhesion, invasion, and homing. Blood. 1998 Jan 15; 91(2):406-18. PMID: 9427693.
      Citations:    
    107. Citro G, D'Agnano I, Leonetti C, Perini R, Bucci B, Zon G, Calabretta B, Zupi G. c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice. Cancer Res. 1998 Jan 15; 58(2):283-9. PMID: 9443406.
      Citations:    
    108. Skorski T, Bellacosa A, Nieborowska-Skorska M, Majewski M, Martinez R, Choi JK, Trotta R, Wlodarski P, Perrotti D, Chan TO, Wasik MA, Tsichlis PN, Calabretta B. Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J. 1997 Oct 15; 16(20):6151-61. PMID: 9321394.
      Citations:    
    109. Amendola R, Martinez R, Negroni A, Venturelli D, Tanno B, Calabretta B, Raschellà G. DR-nm23 gene expression in neuroblastoma cells: relationship to integrin expression, adhesion characteristics, and differentiation. J Natl Cancer Inst. 1997 Sep 3; 89(17):1300-10. PMID: 9293921.
      Citations:    
    110. Bellon T, Perrotti D, Calabretta B. Granulocytic differentiation of normal hematopoietic precursor cells induced by transcription factor PU.1 correlates with negative regulation of the c-myb promoter. Blood. 1997 Sep 1; 90(5):1828-39. PMID: 9292515.
      Citations:    
    111. Calabretta B, Skorski T. Targeting c-myc in leukemia. Anticancer Drug Des. 1997 Jul; 12(5):373-81. PMID: 9236853.
      Citations:    
    112. Santra M, Mann DM, Mercer EW, Skorski T, Calabretta B, Iozzo RV. Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. J Clin Invest. 1997 Jul 1; 100(1):149-57. PMID: 9202067.
      Citations:    
    113. Sorio C, Melotti P, D'Arcangelo D, Mendrola J, Calabretta B, Croce CM, Huebner K. Receptor protein tyrosine phosphatase gamma, Ptp gamma, regulates hematopoietic differentiation. Blood. 1997 Jul 1; 90(1):49-57. PMID: 9207437.
      Citations:    
    114. de Fabritiis P, Skorski T, De Propris MS, Paggi MG, Nieborowska-Skorska M, Lisci A, Buffolino S, Campbell K, Geiser T, Calabretta B. Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells. Leukemia. 1997 Jun; 11(6):811-9. PMID: 9177433.
      Citations:    
    115. Skorski T, Perrotti D, Nieborowska-Skorska M, Gryaznov S, Calabretta B. Antileukemia effect of c-myc N3'-->P5' phosphoramidate antisense oligonucleotides in vivo. Proc Natl Acad Sci U S A. 1997 Apr 15; 94(8):3966-71. PMID: 9108088.
      Citations:    
    116. DeRocco SE, Iozzo R, Ma XP, Schwarting R, Peterson D, Calabretta B. Ectopic expression of A-myb in transgenic mice causes follicular hyperplasia and enhanced B lymphocyte proliferation. Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7):3240-4. PMID: 9096377.
      Citations:    
    117. Salomoni P, Perrotti D, Martinez R, Franceschi C, Calabretta B. Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity. Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7):3296-301. PMID: 9096387.
      Citations:    
    118. Martinez R, Venturelli D, Perrotti D, Veronese ML, Kastury K, Druck T, Huebner K, Calabretta B. Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family. Cancer Res. 1997 Mar 15; 57(6):1180-7. PMID: 9067290.
      Citations:    
    119. Sala A, Kundu M, Casella I, Engelhard A, Calabretta B, Grasso L, Paggi MG, Giordano A, Watson RJ, Khalili K, Peschle C. Activation of human B-MYB by cyclins. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):532-6. PMID: 9012818.
      Citations:    
    120. Skorski T, Nieborowska-Skorska M, Wlodarski P, Perrotti D, Hoser G, Kawiak J, Majewski M, Christensen L, Iozzo RV, Calabretta B. Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides. J Natl Cancer Inst. 1997 Jan 15; 89(2):124-33. PMID: 8998181.
      Citations:    
    121. Calabretta B, Skorski T. Gene regulatory mechanisms operative on hematopoietic cells: proliferation, differentiation, and neoplasia. Crit Rev Eukaryot Gene Expr. 1997; 7(1-2):117-24. PMID: 9034718.
      Citations:    
    122. Scarpa S, Negroni A, Amendola R, Signorelli P, Calabretta B, Modesti A, Raschellà G. Phenotypic and morphological characterization of neuroblastoma cells constitutively expressing B-myb. J Neurooncol. 1997 Jan; 31(1-2):107-14. PMID: 9049836.
      Citations:    
    123. Skorski T, Nieborowska-Skorska M, Wlodarski P, Perrotti D, Martinez R, Wasik MA, Calabretta B. Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):13137-42. PMID: 8917557.
      Citations:    
    124. Perrotti D, Bellón T, Trotta R, Martinez R, Calabretta B. A cell proliferation-dependent multiprotein complex NC-3A positively regulates the CD34 promoter via a TCATTT-containing element. Blood. 1996 Nov 1; 88(9):3336-48. PMID: 8896398.
      Citations:    
    125. Calabretta B, Skorski T. BCR/ABL regulation of PI-3 kinase activity. Leuk Lymphoma. 1996 Nov; 23(5-6):473-6. PMID: 9031078.
      Citations:    
    126. Cucco C, Calabretta B. In vitro and in vivo reversal of multidrug resistance in a human leukemia-resistant cell line by mdr1 antisense oligodeoxynucleotides. Cancer Res. 1996 Oct 1; 56(19):4332-7. PMID: 8813118.
      Citations:    
    127. Del Bufalo D, Cucco C, Leonetti C, Citro G, D'Agnano I, Benassi M, Geiser T, Zon G, Calabretta B, Zupi G. Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo. Br J Cancer. 1996 Aug; 74(3):387-93. PMID: 8695353.
      Citations:    
    128. Skorski T, Nieborowska-Skorska M, Wlodarski P, Zon G, Iozzo RV, Calabretta B. Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice. Blood. 1996 Aug 1; 88(3):1005-12. PMID: 8704208.
      Citations:    
    129. Melotti P, Calabretta B. The transcription factors c-myb and GATA-2 act independently in the regulation of normal hematopoiesis. Proc Natl Acad Sci U S A. 1996 May 28; 93(11):5313-8. PMID: 8643572.
      Citations:    
    130. Sala A, Casella I, Bellon T, Calabretta B, Watson RJ, Peschle C. B-myb promotes S phase and is a downstream target of the negative regulator p107 in human cells. J Biol Chem. 1996 Apr 19; 271(16):9363-7. PMID: 8621601.
      Citations:    
    131. Gryaznov S, Skorski T, Cucco C, Nieborowska-Skorska M, Chiu CY, Lloyd D, Chen JK, Koziolkiewicz M, Calabretta B. Oligonucleotide N3'-->P5' phosphoramidates as antisense agents. Nucleic Acids Res. 1996 Apr 15; 24(8):1508-14. PMID: 8628685.
      Citations:    
    132. Leonetti C, D'Agnano I, Lozupone F, Valentini A, Geiser T, Zon G, Calabretta B, Citro G C, Zupi G. Antitumor effect of c-myc antisense phosphorothioate oligodeoxynucleotides on human melanoma cells in vitro and and in mice. J Natl Cancer Inst. 1996 Apr 3; 88(7):419-29. PMID: 8618233.
      Citations:    
    133. Melotti P, Calabretta B. Induction of hematopoietic commitment and erythromyeloid differentiation in embryonal stem cells constitutively expressing c-myb. Blood. 1996 Mar 15; 87(6):2221-34. PMID: 8630382.
      Citations:    
    134. Fidanza V, Melotti P, Yano T, Nakamura T, Bradley A, Canaani E, Calabretta B, Croce CM. Double knockout of the ALL-1 gene blocks hematopoietic differentiation in vitro. Cancer Res. 1996 Mar 15; 56(6):1179-83. PMID: 8640793.
      Citations:    
    135. Raschellà G, Negroni A, Pucci S, Amendola R, Valeri S, Calabretta B. B-myb transcriptional regulation and mRNA stability during differentiation of neuroblastoma cells. Exp Cell Res. 1996 Feb 1; 222(2):395-9. PMID: 8598228.
      Citations:    
    136. Calabretta B, Skorski T, Ratajczak MZ, Gewirtz AM. Antisense strategies in the treatment of leukemias. Semin Oncol. 1996 Feb; 23(1):78-87. PMID: 8607034.
      Citations:    
    137. Nieborowska-Skórska M, Bialek AP, Nicolaides NC, Iozzo RV, Kawalec M, Calabretta B, Kawiak J, Marlicz K, Skórski T. The influence of phosphorothioate oligodeoxynucleotides on various organs in vivo. Folia Histochem Cytobiol. 1996; 34(2):69-73. PMID: 8875213.
      Citations:    
    138. Szczylik C, Skórski T, Malaguarnera L, Hetman J, Chen ST, Calabretta B. Inhibition of in vitro proliferation of chronic myelogenous leukemia progenitor cells by c-myb antisense oligodeoxynucleotides. Folia Histochem Cytobiol. 1996; 34(3-4):129-34. PMID: 8967957.
      Citations:    
    139. Skorski T, Nieborowska-Skorska M, Campbell K, Iozzo RV, Zon G, Darzynkiewicz Z, Calabretta B. Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes. J Exp Med. 1995 Dec 1; 182(6):1645-53. PMID: 7500009.
      Citations:    
    140. Perrotti D, Melotti P, Skorski T, Casella I, Peschle C, Calabretta B. Overexpression of the zinc finger protein MZF1 inhibits hematopoietic development from embryonic stem cells: correlation with negative regulation of CD34 and c-myb promoter activity. Mol Cell Biol. 1995 Nov; 15(11):6075-87. PMID: 7565760.
      Citations:    
    141. Sala A, Bellon T, Melotti P, Peschle C, Calabretta B. Inhibition of erythro-myeloid differentiation by constitutive expression of a DNA binding-deficient c-myb mutant: implication for c-myb function. Blood. 1995 Nov 1; 86(9):3404-12. PMID: 7579444.
      Citations:    
    142. Venturelli D, Martinez R, Melotti P, Casella I, Peschle C, Cucco C, Spampinato G, Darzynkiewicz Z, Calabretta B. Overexpression of DR-nm23, a protein encoded by a member of the nm23 gene family, inhibits granulocyte differentiation and induces apoptosis in 32Dc13 myeloid cells. Proc Natl Acad Sci U S A. 1995 Aug 1; 92(16):7435-9. PMID: 7638209.
      Citations:    
    143. Santra M, Skorski T, Calabretta B, Lattime EC, Iozzo RV. De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells. Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15):7016-20. PMID: 7624361.
      Citations:    
    144. Skorski T, Kanakaraj P, Nieborowska-Skorska M, Ratajczak MZ, Wen SC, Zon G, Gewirtz AM, Perussia B, Calabretta B. Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells. Blood. 1995 Jul 15; 86(2):726-36. PMID: 7606002.
      Citations:    
    145. de Fabritiis P, Calabretta B. Antisense oligodeoxynucleotides for the treatment of chronic myelogenous leukemia: are they still a promise? Haematologica. 1995 Jul-Aug; 80(4):295-9. PMID: 7590496.
      Citations:    
    146. Skorski T, Nieborowska-Skorska M, Szczylik C, Kanakaraj P, Perrotti D, Zon G, Gewirtz A, Perussia B, Calabretta B. C-RAF-1 serine/threonine kinase is required in BCR/ABL-dependent and normal hematopoiesis. Cancer Res. 1995 Jun 1; 55(11):2275-8. PMID: 7757976.
      Citations:    
    147. Raschellà G, Negroni A, Sala A, Pucci S, Romeo A, Calabretta B. Requirement of b-myb function for survival and differentiative potential of human neuroblastoma cells. J Biol Chem. 1995 Apr 14; 270(15):8540-5. PMID: 7721753.
      Citations:    
    148. de Fabritis P, Amadori S, Petti MC, Mancini M, Montefusco E, Picardi A, Geiser T, Campbell K, Calabretta B, Mandelli F. In vitro purging with BCR-ABL antisense oligodeoxynucleotides does not prevent haematologic reconstitution after autologous bone marrow transplantation. Leukemia. 1995 Apr; 9(4):662-4. PMID: 7536864.
      Citations:    
    149. Wen SC, Ku DH, De Luca A, Claudio PP, Giordano A, Calabretta B. ets-2 regulates cdc2 kinase activity in mammalian cells: coordinated expression of cdc2 and cyclin A. Exp Cell Res. 1995 Mar; 217(1):8-14. PMID: 7867724.
      Citations:    
    150. Azzoni L, Anegon I, Calabretta B, Perussia B. Ligand binding to Fc gamma R induces c-myc-dependent apoptosis in IL-2-stimulated NK cells. J Immunol. 1995 Jan 15; 154(2):491-9. PMID: 7814862.
      Citations:    
    151. Fertala J, Nieborowska-Skórska M, Calabretta B, Skórski T. The diverse effect of topoisomerase I specific inhibitor (camptothecin) on normal and BCR/ABL-dependent hematopoietic cells proliferation: therapeutic implications. Folia Histochem Cytobiol. 1995; 33(3):187-92. PMID: 8612872.
      Citations:    
    152. Ma XP, Calabretta B. DNA binding and transactivation activity of A-myb, a c-myb-related gene. Cancer Res. 1994 Dec 15; 54(24):6512-6. PMID: 7987850.
      Citations:    
    153. Claudio PP, Howard CM, Baldi A, De Luca A, Fu Y, Condorelli G, Sun Y, Colburn N, Calabretta B, Giordano A. p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107. Cancer Res. 1994 Nov 1; 54(21):5556-60. PMID: 7923196.
      Citations:    
    154. Melotti P, Calabretta B. Ets-2 and c-Myb act independently in regulating expression of the hematopoietic stem cell antigen CD34. J Biol Chem. 1994 Oct 14; 269(41):25303-9. PMID: 7523384.
      Citations:    
    155. Skorski T, Kanakaraj P, Ku DH, Nieborowska-Skorska M, Canaani E, Zon G, Perussia B, Calabretta B. Negative regulation of p120GAP GTPase promoting activity by p210bcr/abl: implication for RAS-dependent Philadelphia chromosome positive cell growth. J Exp Med. 1994 Jun 1; 179(6):1855-65. PMID: 8195713.
      Citations:    
    156. Skorski T, Nieborowska-Skorska M, Nicolaides NC, Szczylik C, Iversen P, Iozzo RV, Zon G, Calabretta B. Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4504-8. PMID: 8183938.
      Citations:    
    157. Soddu S, Blandino G, Citro G, Scardigli R, Piaggio G, Ferber A, Calabretta B, Sacchi A. Wild-type p53 gene expression induces granulocytic differentiation of HL-60 cells. Blood. 1994 Apr 15; 83(8):2230-7. PMID: 8161788.
      Citations:    
    158. Raschella G, Romeo A, Negroni A, Pucci S, Dominici C, Castello MA, Bevilacqua P, Felsani A, Calabretta B. Lack of correlation between N-myc and MAX expression in neuroblastoma tumors and in cell lines: implication for N-myc-MAX complex formation. Cancer Res. 1994 Apr 15; 54(8):2251-5. PMID: 8174135.
      Citations:    
    159. Sala A, Nicolaides NC, Engelhard A, Bellon T, Lawe DC, Arnold A, Graña X, Giordano A, Calabretta B. Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells. Cancer Res. 1994 Mar 15; 54(6):1402-6. PMID: 8137237.
      Citations:    
    160. Citro G, Szczylik C, Ginobbi P, Zupi G, Calabretta B. Inhibition of leukaemia cell proliferation by folic acid-polylysine-mediated introduction of c-myb antisense oligodeoxynucleotides into HL-60 cells. Br J Cancer. 1994 Mar; 69(3):463-7. PMID: 8123474.
      Citations:    
    161. Melotti P, Ku DH, Calabretta B. Regulation of the expression of the hematopoietic stem cell antigen CD34: role of c-myb. J Exp Med. 1994 Mar 1; 179(3):1023-8. PMID: 7509358.
      Citations:    
    162. Smetsers TF, Skorski T, van de Locht LT, Wessels HM, Pennings AH, de Witte T, Calabretta B, Mensink EJ. Antisense BCR-ABL oligonucleotides induce apoptosis in the Philadelphia chromosome-positive cell line BV173. Leukemia. 1994 Jan; 8(1):129-40. PMID: 8289478.
      Citations:    
    163. Nieborowska-Skórska M, Nakashima M, Ratajczak M, Steplewski Z, Calabretta B, Skórski T. Oncogene-targeted antisense oligodeoxynucleotides combined with chemotherapy or immunotherapy: a new approach for tumor treatment? Folia Histochem Cytobiol. 1994; 32(1):35-40. PMID: 8026602.
      Citations:    
    164. Piacentini M, Raschellá G, Calabretta B, Melino G. c-myb down regulation is associated with apoptosis in human neuroblastoma cells. Cell Death Differ. 1994; 1(2):85-92. PMID: 17180021.
      Citations:    
    165. Nieborowska-Skórska M, Ratajczak MZ, Calabretta B, Skórski T. The role of c-Myc protooncogene in chronic myelogenous leukemia. Folia Histochem Cytobiol. 1994; 32(4):231-4. PMID: 7758616.
      Citations:    
    166. Skorski T, Kanakaraj P, Nieborowska-Skorska M, Ratajczak M, Szczylik C, Zon G, Arlinghaus RB, Gewirtz A, Perussia B, Calabretta B. p120 GAP requirement in normal and malignant human hematopoiesis. J Exp Med. 1993 Dec 1; 178(6):1923-33. PMID: 8245773.
      Citations:    
    167. de Fabritiis P, Amadori S, Calabretta B, Mandelli F. Elimination of clonogenic Philadelphia-positive cells using BCR-ABL antisense oligodeoxynucleotides. Bone Marrow Transplant. 1993 Sep; 12(3):261-5. PMID: 8241986.
      Citations:    
    168. Szczylik C, Skorski T, Ku DH, Nicolaides NC, Wen SC, Rudnicka L, Bonati A, Malaguarnera L, Calabretta B. Regulation of proliferation and cytokine expression of bone marrow fibroblasts: role of c-myb. J Exp Med. 1993 Sep 1; 178(3):997-1005. PMID: 7688794.
      Citations:    
    169. Rizzo MG, Soddu S, Tibursi G, Calabretta B, Sacchi A. Wild-type p53 differentially affects tumorigenic and metastatic potential of murine metastatic cell variants. Clin Exp Metastasis. 1993 Sep; 11(5):368-76. PMID: 8375112.
      Citations:    
    170. Skorski T, Nieborowska-Skorska M, Barletta C, Malaguarnera L, Szcyzlik C, Chen ST, Lange B, Calabretta B. Highly efficient elimination of Philadelphia leukemic cells by exposure to bcr/abl antisense oligodeoxynucleotides combined with mafosfamide. J Clin Invest. 1993 Jul; 92(1):194-202. PMID: 8325984.
      Citations:    
    171. Calabretta B, Skorski T, Szczylik C, Zon G. Prospects for gene-directed therapy with antisense oligodeoxynucleotides. Cancer Treat Rev. 1993 Apr; 19(2):169-79. PMID: 8481928.
      Citations:    
    172. Ku DH, Wen SC, Engelhard A, Nicolaides NC, Lipson KE, Marino TA, Calabretta B. c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene. J Biol Chem. 1993 Jan 25; 268(3):2255-9. PMID: 8420994.
      Citations:    
    173. Nieborowska-Skórska M, Skórski T, Ratajczak MZ, Szczylik C, Malaguarnera L, Calabretta B. Successful mafosfamide purging of bone marrow from chronic myelogenous leukemia (CML) cells. Folia Histochem Cytobiol. 1993; 31(4):161-7. PMID: 8137996.
      Citations:    
    174. Calabretta B, Venturelli D, Gewirtz AM. Functional significance of c-myb expression in normal and leukemic hematopoiesis. Cancer Invest. 1993; 11(2):191-7. PMID: 8462020.
      Citations:    
    175. Calabretta B, Skorski T, Zon G. Antisense oligonucleotides. Semin Cancer Biol. 1992 Dec; 3(6):391-8. PMID: 1286160.
      Citations:    
    176. Sala A, Calabretta B. Regulation of BALB/c 3T3 fibroblast proliferation by B-myb is accompanied by selective activation of cdc2 and cyclin D1 expression. Proc Natl Acad Sci U S A. 1992 Nov 1; 89(21):10415-9. PMID: 1438227.
      Citations:    
    177. Calabretta B, Skorski T, Szczylik C, Caracciolo D, Valtieri M, Venturelli D. Protooncogenes in the regulation of normal hematopoiesis. An antisense approach. Ann N Y Acad Sci. 1992 Oct 28; 660:117-23. PMID: 1285069.
      Citations:    
    178. Nicolaides NC, Correa I, Casadevall C, Travali S, Soprano KJ, Calabretta B. The Jun family members, c-Jun and JunD, transactivate the human c-myb promoter via an Ap1-like element. J Biol Chem. 1992 Sep 25; 267(27):19665-72. PMID: 1527086.
      Citations:    
    179. Citro G, Perrotti D, Cucco C, D'Agnano I, Sacchi A, Zupi G, Calabretta B. Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligodeoxynucleotides. Proc Natl Acad Sci U S A. 1992 Aug 1; 89(15):7031-5. PMID: 1495997.
      Citations:    
    180. Raschellà G, Negroni A, Skorski T, Pucci S, Nieborowska-Skorska M, Romeo A, Calabretta B. Inhibition of proliferation by c-myb antisense RNA and oligodeoxynucleotides in transformed neuroectodermal cell lines. Cancer Res. 1992 Aug 1; 52(15):4221-6. PMID: 1638535.
      Citations:    
    181. Skorski T, Szczylik C, Ratajczak MZ, Malaguarnera L, Gewirtz AM, Calabretta B. Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides. J Exp Med. 1992 Mar 1; 175(3):743-50. PMID: 1371302.
      Citations:    
    182. Skórski T, Nieborowska-Skórska M, Calabretta B. A model of Ph' positive chronic myeloid leukemia-blast crisis cell line growth in immunodeficient SCID mice. Folia Histochem Cytobiol. 1992; 30(3):91-6. PMID: 1286728.
      Citations:    
    183. Calabretta B, Nicolaides NC. c-myb and growth control. Crit Rev Eukaryot Gene Expr. 1992; 2(3):225-35. PMID: 1511186.
      Citations:    
    184. Nicolaides NC, Gualdi R, Casadevall C, Manzella L, Calabretta B. Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene. Mol Cell Biol. 1991 Dec; 11(12):6166-76. PMID: 1944282.
      Citations:    
    185. Calabretta B. Inhibition of protooncogene expression by antisense oligodeoxynucleotides: biological and therapeutic implications. Cancer Res. 1991 Sep 1; 51(17):4505-10. PMID: 1873794.
      Citations:    
    186. Reiss K, Travali S, Calabretta B, Baserga R. Growth regulated expression of B-myb in fibroblasts and hematopoietic cells. J Cell Physiol. 1991 Sep; 148(3):338-43. PMID: 1717494.
      Citations:    
    187. Szczylik C, Skorski T, Nicolaides NC, Manzella L, Malaguarnera L, Venturelli D, Gewirtz AM, Calabretta B. Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides. Science. 1991 Aug 2; 253(5019):562-5. PMID: 1857987.
      Citations:    
    188. Barletta C, Druck T, LaForgia S, Calabretta B, Drabkin H, Patterson D, Croce CM, Huebner K. Chromosome locations of the MYB related genes, AMYB and BMYB. Cancer Res. 1991 Jul 15; 51(14):3821-4. PMID: 2065336.
      Citations:    
    189. Travali S, Ferber A, Reiss K, Sell C, Koniecki J, Calabretta B, Baserga R. Effect of the myb gene product on expression of the PCNA gene in fibroblasts. Oncogene. 1991 Jun; 6(6):887-94. PMID: 1712444.
      Citations:    
    190. Melani C, Rivoltini L, Parmiani G, Calabretta B, Colombo MP. Inhibition of proliferation by c-myb antisense oligodeoxynucleotides in colon adenocarcinoma cell lines that express c-myb. Cancer Res. 1991 Jun 1; 51(11):2897-901. PMID: 2032228.
      Citations:    
    191. Calabretta B, Sims RB, Valtieri M, Caracciolo D, Szczylik C, Venturelli D, Ratajczak M, Beran M, Gewirtz AM. Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2351-5. PMID: 2006173.
      Citations:    
    192. Valtieri M, Venturelli D, Caré A, Fossati C, Pelosi E, Labbaye C, Mattia G, Gewirtz AM, Calabretta B, Peschle C. Antisense myb inhibition of purified erythroid progenitors in development and differentiation is linked to cycling activity and expression of DNA polymerase alpha. Blood. 1991 Mar 15; 77(6):1181-90. PMID: 1705831.
      Citations:    
    193. Travali S, Reiss K, Ferber A, Petralia S, Mercer WE, Calabretta B, Baserga R. Constitutively expressed c-myb abrogates the requirement for insulinlike growth factor 1 in 3T3 fibroblasts. Mol Cell Biol. 1991 Feb; 11(2):731-6. PMID: 1990279.
      Citations:    
    194. Gewirtz AM, Calabretta B. Role of the c-myb and c-abl protooncogenes in human hematopoiesis. Ann N Y Acad Sci. 1991; 628:63-73. PMID: 2069323.
      Citations:    
    195. Skórski T, Szczylik C, Malaguarnera L, Calabretta B. Gene-targeted specific inhibition of chronic myeloid leukemia cell growth by BCR-ABL antisense oligodeoxynucleotides. Folia Histochem Cytobiol. 1991; 29(3):85-9. PMID: 1794439.
      Citations:    
    196. Venturelli D, Mariano MT, Szczylik C, Valtieri M, Lange B, Crist W, Link M, Calabretta B. Down-regulated c-myb expression inhibits DNA synthesis of T-leukemia cells in most patients. Cancer Res. 1990 Nov 15; 50(22):7371-5. PMID: 2224864.
      Citations:    
    197. Venturelli D, Travali S, Calabretta B. Inhibition of T-cell proliferation by a MYB antisense oligomer is accompanied by selective down-regulation of DNA polymerase alpha expression. Proc Natl Acad Sci U S A. 1990 Aug; 87(15):5963-7. PMID: 1696013.
      Citations:    
    198. Valtieri M, Gabbianelli M, Pelosi E, Testa U, Labbaye C, Mattia G, Fossati C, Venturelli D, Gewirtz AM, Calabretta B, et al. Molecular mechanisms underlying erythropoiesis: cycling activity of adult BFU-e relates to their requirement for c-myb function and potential for HbF synthesis. Int J Cell Cloning. 1990 Jan; 8 Suppl 1:314-34. PMID: 1691249.
      Citations:    
    199. Caracciolo D, Venturelli D, Valtieri M, Peschle C, Gewirtz AM, Calabretta B. Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis. J Clin Invest. 1990 Jan; 85(1):55-61. PMID: 2404028.
      Citations:    
    200. Caracciolo D, Valtieri M, Venturelli D, Peschle C, Gewirtz AM, Calabretta B. Lineage-specific requirement of c-abl function in normal hematopoiesis. Science. 1989 Sep 8; 245(4922):1107-10. PMID: 2672339.
      Citations:    
    201. Palumbo AP, Pileri A, Dianzani U, Massaia M, Boccadoro M, Calabretta B. Altered expression of growth-regulated protooncogenes in human malignant plasma cells. Cancer Res. 1989 Sep 1; 49(17):4701-4. PMID: 2667753.
      Citations:    
    202. Gewirtz AM, Anfossi G, Venturelli D, Valpreda S, Sims R, Calabretta B. G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb. Science. 1989 Jul 14; 245(4914):180-3. PMID: 2665077.
      Citations:    
    203. Ku DH, Travali S, Calabretta B, Huebner K, Baserga R. Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20. Somat Cell Mol Genet. 1989 Jul; 15(4):297-307. PMID: 2569765.
      Citations:    
    204. Ferrari S, Tagliafico E, Ceccherelli G, Selleri L, Calabretta B, Donelli A, Temperani P, Sarti M, Sacchi S, Emilia G, et al. Expression of the myeloperoxidase gene in acute and chronic myeloid leukemias: relationship to the expression of cell cycle-related genes. Leukemia. 1989 Jun; 3(6):423-30. PMID: 2542700.
      Citations:    
    205. Travali S, Ku DH, Rizzo MG, Ottavio L, Baserga R, Calabretta B. Structure of the human gene for the proliferating cell nuclear antigen. J Biol Chem. 1989 May 5; 264(13):7466-72. PMID: 2565339.
      Citations:    
    206. Gewirtz AM, Calabretta B, Rucinski B, Niewiarowski S, Xu WY. Inhibition of human megakaryocytopoiesis in vitro by platelet factor 4 (PF4) and a synthetic COOH-terminal PF4 peptide. J Clin Invest. 1989 May; 83(5):1477-86. PMID: 2523411.
      Citations:    
    207. Anfossi G, Gewirtz AM, Calabretta B. An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proc Natl Acad Sci U S A. 1989 May; 86(9):3379-83. PMID: 2541445.
      Citations:    
    208. Ferrari S, Calabretta B, Selleri L, Ceccherelli G, Torelli G, Torelli U. Expression of oncogenes and cell cycle related genes in acute and chronic leukemias. Leukemia. 1988 Dec; 2(12 Suppl):160S-166S. PMID: 3199878.
      Citations:    
    209. Jaskulski D, Gatti C, Travali S, Calabretta B, Baserga R. Regulation of the proliferating cell nuclear antigen cyclin and thymidine kinase mRNA levels by growth factors. J Biol Chem. 1988 Jul 25; 263(21):10175-9. PMID: 2899075.
      Citations:    
    210. Jaskulski D, deRiel JK, Mercer WE, Calabretta B, Baserga R. Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin. Science. 1988 Jun 10; 240(4858):1544-6. PMID: 2897717.
      Citations:    
    211. Venturelli D, Lange B, Narni F, Selleri L, Mariano MT, Torelli U, Gewirtz AM, Calabretta B. Prognostic significance of "short-term" effects of chemotherapy on MYC and histone H3 mRNA levels in acute leukemia patients. Proc Natl Acad Sci U S A. 1988 May; 85(10):3590-4. PMID: 3285345.
      Citations:    
    212. Baserga R, Calabretta B, Travali S, Jaskulski D, Lipson KE, deRiel JK. Regulation of the expression of cell cycle genes. Ann N Y Acad Sci. 1988; 551:283-9. PMID: 2907721.
      Citations:    
    213. Ferrari S, Calabretta B, Battini R, Cosenza SC, Owen TA, Soprano KJ, Baserga R. Expression of c-myc and induction of DNA synthesis by platelet-poor plasma in human diploid fibroblasts. Exp Cell Res. 1988 Jan; 174(1):25-33. PMID: 2446899.
      Citations:    
    214. Kaczmarek L, Calabretta B, Elfenbein IB, Mercer WE. Cell cycle analysis of human peripheral blood T lymphocytes in long-term culture. Exp Cell Res. 1987 Nov; 173(1):70-9. PMID: 2445595.
      Citations:    
    215. Torelli G, Venturelli D, Coló A, Zanni C, Selleri L, Moretti L, Calabretta B, Torelli U. Expression of c-myb protooncogene and other cell cycle-related genes in normal and neoplastic human colonic mucosa. Cancer Res. 1987 Oct 15; 47(20):5266-9. PMID: 3652034.
      Citations:    
    216. Calabretta B, Mercer WE. TPA-induction of c-fos mRNA during the cell cycle of WI-38 human fibroblasts. Biochem Biophys Res Commun. 1987 Sep 15; 147(2):716-23. PMID: 3632695.
      Citations:    
    217. Kaczmarek L, Calabretta B, Ferrari S, de Riel JK. Cell-cycle-dependent expression of human ornithine decarboxylase. J Cell Physiol. 1987 Sep; 132(3):545-51. PMID: 3308908.
      Citations:    
    218. Ferrari S, Calabretta B, deRiel JK, Battini R, Ghezzo F, Lauret E, Griffin C, Emanuel BS, Gurrieri F, Baserga R. Structural and functional analysis of a growth-regulated gene, the human calcyclin. J Biol Chem. 1987 Jun 15; 262(17):8325-32. PMID: 3036810.
      Citations:    
    219. Battini R, Ferrari S, Kaczmarek L, Calabretta B, Chen ST, Baserga R. Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated. J Biol Chem. 1987 Mar 25; 262(9):4355-9. PMID: 3031073.
      Citations:    
    220. Kaczmarek L, Calabretta B, Kao HT, Heintz N, Nevins J, Baserga R. Control of hsp70 RNA levels in human lymphocytes. J Cell Biol. 1987 Feb; 104(2):183-7. PMID: 3492498.
      Citations:    
    221. Calabretta B. Dissociation of c-fos induction from macrophage differentiation in human myeloid leukemic cell lines. Mol Cell Biol. 1987 Feb; 7(2):769-74. PMID: 3547082.
      Citations:    
    222. Ferrari S, Battini R, Kaczmarek L, Rittling S, Calabretta B, de Riel JK, Philiponis V, Wei JF, Baserga R. Coding sequence and growth regulation of the human vimentin gene. Mol Cell Biol. 1986 Nov; 6(11):3614-20. PMID: 3467175.
      Citations:    
    223. Calabretta B, Kaczmarek L, Selleri L, Torelli G, Ming PM, Ming SC, Mercer WE. Growth-dependent expression of human Mr 53,000 tumor antigen messenger RNA in normal and neoplastic cells. Cancer Res. 1986 Nov; 46(11):5738-42. PMID: 3019534.
      Citations:    
    224. Ferrari S, Narni F, Mars W, Kaczmarek L, Venturelli D, Anderson B, Calabretta B. Expression of growth-regulated genes in human acute leukemias. Cancer Res. 1986 Oct; 46(10):5162-6. PMID: 3756869.
      Citations:    
    225. Calabretta B, Battini R, Kaczmarek L, de Riel JK, Baserga R. Molecular cloning of the cDNA for a growth factor-inducible gene with strong homology to S-100, a calcium-binding protein. J Biol Chem. 1986 Sep 25; 261(27):12628-32. PMID: 3755724.
      Citations:    
    226. Gibson CW, Rittling SR, Hirschhorn RR, Kaczmarek L, Calabretta B, Stiles CD, Baserga R. Cell cycle dependent genes inducible by different mitogens in cells from different species. Mol Cell Biochem. 1986 Jun; 71(1):61-9. PMID: 3755218.
      Citations:    
    227. Calabretta B, Venturelli D, Kaczmarek L, Narni F, Talpaz M, Anderson B, Beran M, Baserga R. Altered expression of G1-specific genes in human malignant myeloid cells. Proc Natl Acad Sci U S A. 1986 Mar; 83(5):1495-8. PMID: 3513178.
      Citations:    
    228. Kaczmarek L, Calabretta B, Baserga R. Effect of interleukin-2 on the expression of cell cycle genes in human T lymphocytes. Biochem Biophys Res Commun. 1985 Dec 17; 133(2):410-6. PMID: 3878709.
      Citations:    
    229. Kaczmarek L, Calabretta B, Baserga R. Expression of cell-cycle-dependent genes in phytohemagglutinin-stimulated human lymphocytes. Proc Natl Acad Sci U S A. 1985 Aug; 82(16):5375-9. PMID: 2410921.
      Citations:    
    230. Calabretta B, Kaczmarek L, Mars W, Ochoa D, Gibson CW, Hirschhorn RR, Baserga R. Cell-cycle-specific genes differentially expressed in human leukemias. Proc Natl Acad Sci U S A. 1985 Jul; 82(13):4463-7. PMID: 3859871.
      Citations:    
    231. Torelli U, Torelli G, Narni F, Donelli A, Ferrari S, Franchini G, Calabretta B. Different frequency classes of sequences in heterogeneous nuclear RNA of normal promyelocytes and lymphoblasts and of leukemic blast cells of circulating blood and of the HL60 line. Haematol Blood Transfus. 1981; 26:517-9. PMID: 7319295.
      Citations:    
    232. Torelli UL, Ferrari S, Franchini G, Donelli A, Narni F, Calabretta B, Torelli G. Immunological evidence for the presence of double-stranded RNA regions in intact nuclei of normal human lymphocytes. Haematologica. 1979 Dec; 64(6):681-5. PMID: 121083.
      Citations:    
    233. Torelli G, Narni F, Franchini G, Donelli A, Ferrari S, Calabretta B, Torelli U, Bosi P. Kinetics of hybridization to human DNA of heterogeneous nuclear RNA isolated from normal human lymphoblasts and acute leukemia blast cells. Mol Biol Rep. 1979 Aug 31; 5(3):181-4. PMID: 290855.
      Citations:    
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