David Strayer

TitleProfessor
InstitutionThomas Jefferson University
DepartmentPathology & Genomic Medicine
Address1020 Locust St.
Philadelphia PA 19107
Phone215-503-1087
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dennie D, Louboutin JP, Strayer DS. Migration of bone marrow progenitor cells in the adult brain of rats and rabbits. World J Stem Cells. 2016 Apr 26; 8(4):136-57. PMID: 27114746.
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    2. Steiner JP, Bachani M, Wolfson-Stofko B, Lee MH, Wang T, Wang T, Li G, Li W, Strayer D, Haughey NJ, Nath A. Interaction of paroxetine with mitochondrial proteins mediates neuroprotection. Neurotherapeutics. 2015 Jan; 12(1):200-16. PMID: 25404050.
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    3. Louboutin JP, Strayer D. Role of Oxidative Stress in HIV-1-Associated Neurocognitive Disorder and Protection by Gene Delivery of Antioxidant Enzymes. Antioxidants (Basel). 2014 Nov 18; 3(4):770-97. PMID: 26785240.
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    4. Strayer DR, Carter WA, Stouch BC, Stittelaar KJ, Thoolen RJ, Osterhaus AD, Mitchell WM. Protection from pulmonary tissue damage associated with infection of cynomolgus macaques by highly pathogenic avian influenza virus (H5N1) by low dose natural human IFN-a administered to the buccal mucosa. Antiviral Res. 2014 Oct; 110:175-80. PMID: 25111905.
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    5. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. Oxidative Stress Is Associated with Neuroinflammation in Animal Models of HIV-1 Tat Neurotoxicity. Antioxidants (Basel). 2014 May 16; 3(2):414-38. PMID: 26784879.
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    6. Mitchell WM, Nicodemus CF, Carter WA, Horvath JC, Strayer DR. Discordant biological and toxicological species responses to TLR3 activation. Am J Pathol. 2014 Apr; 184(4):1062-1072. PMID: 24486326.
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    7. Louboutin JP, Strayer DS. Relationship between the chemokine receptor CCR5 and microglia in neurological disorders: consequences of targeting CCR5 on neuroinflammation, neuronal death and regeneration in a model of epilepsy. CNS Neurol Disord Drug Targets. 2013 Sep; 12(6):815-29. PMID: 24047524.
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    8. Strayer DS. Raphael Rubin, 1956-2011. Alcohol Clin Exp Res. 2012 Nov; 36(11):1835-6. PMID: 22998597.
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    9. Kang S, Louboutin JP, Datta P, Landel CP, Martinez D, Zervos AS, Strayer DS, Fernandes-Alnemri T, Alnemri ES. Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging. Cell Death Differ. 2013 Feb; 20(2):259-69. PMID: 22976834.
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    10. Louboutin JP, Marusich E, Gao E, Agrawal L, Koch WJ, Strayer DS. Ethanol protects from injury due to ischemia and reperfusion by increasing vascularity via vascular endothelial growth factor. Alcohol. 2012 Aug; 46(5):441-54. PMID: 22560293.
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    11. Louboutin JP, Agrawal L, Reyes BA, van Bockstaele EJ, Strayer DS. Gene delivery of antioxidant enzymes inhibits human immunodeficiency virus type 1 gp120-induced expression of caspases. Neuroscience. 2012 Jul 12; 214:68-77. PMID: 22531373.
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    12. Louboutin JP, Strayer DS. Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications. ScientificWorldJournal. 2012; 2012:482575. PMID: 22448134.
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    13. Strayer DR, Carter WA. Recombinant and natural human interferons: analysis of the incidence and clinical impact of neutralizing antibodies. J Interferon Cytokine Res. 2012 Mar; 32(3):95-102. PMID: 22132684.
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    14. Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy. Eur J Neurosci. 2011 Dec; 34(12):2015-23. PMID: 22092673.
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    15. Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis. 2012 Feb; 45(2):657-70. PMID: 22036626.
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    16. Louboutin JP, Chekmasova AA, Reyes BA, Van Bockstaele EJ, Strayer DS. Bone marrow-derived cells migrate to line the vessels of the CNS: opportunities for gene delivery to CNS vasculature. Neuroscience. 2011 Nov 10; 195:215-23. PMID: 21906658.
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    17. Marusich E, Louboutin JP, Chekmasova AA, Strayer DS. Lymphocyte adhesion to CCR5 ligands is reduced by anti-CCR5 gene delivery. J Neurol Sci. 2011 Sep 15; 308(1-2):25-7. PMID: 21741662.
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    18. Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. Intracisternal rSV40 administration provides effective pan-CNS transgene expression. Gene Ther. 2012 Jan; 19(1):114-8. PMID: 21614027.
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    19. Louboutin JP, Marusich E, Fisher-Perkins J, Dufour JP, Bunnell BA, Strayer DS. Gene transfer to the rhesus monkey brain using SV40-derived vectors is durable and safe. Gene Ther. 2011 Jul; 18(7):682-91. PMID: 21368898.
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    20. Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. Gene transfer to the cerebellum. Cerebellum. 2010 Dec; 9(4):587-97. PMID: 20700772.
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    21. Louboutin JP, Chekmasova AA, Marusich E, Chowdhury JR, Strayer DS. Efficient CNS gene delivery by intravenous injection. Nat Methods. 2010 Nov; 7(11):905-7. PMID: 20953176.
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    22. Louboutin JP, Chekmasova A, Marusich E, Agrawal L, Strayer DS. Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage. FASEB J. 2011 Feb; 25(2):737-53. PMID: 20940264.
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    23. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. J Neuropathol Exp Neurol. 2010 Aug; 69(8):801-16. PMID: 20613638.
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    24. Strayer DS, Mitchell C, Maier DA, Nichols CN. Production of SV40-derived vectors. Cold Spring Harb Protoc. 2010 Jun; 2010(6):pdb.prot5436. PMID: 20516174.
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    25. Strayer DS, Mitchell C, Maier DA, Nichols CN. Titering replication-defective rSV40 vectors. Cold Spring Harb Protoc. 2010 Jun; 2010(6):pdb.prot5437. PMID: 20516175.
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    26. Louboutin JP, Reyes BA, Agrawal L, Maxwell CR, Van Bockstaele EJ, Strayer DS. Blood-brain barrier abnormalities caused by exposure to HIV-1 gp120--protection by gene delivery of antioxidant enzymes. Neurobiol Dis. 2010 May; 38(2):313-25. PMID: 20219678.
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    27. Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes. Exp Neurol. 2010 Jan; 221(1):231-45. PMID: 19913017.
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    28. Mueller C, Strayer MS, Sirninger J, Braag S, Branco F, Louboutin JP, Flotte TR, Strayer DS. In vitro and in vivo functional characterization of gutless recombinant SV40-derived CFTR vectors. Gene Ther. 2010 Feb; 17(2):227-37. PMID: 19890354.
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    29. Agrawal L, Louboutin JP, Marusich E, Reyes BA, Van Bockstaele EJ, Strayer DS. Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res. 2010 Jan 08; 1306:116-30. PMID: 19815008.
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    30. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. A rat model of human immunodeficiency virus 1 encephalopathy using envelope glycoprotein gp120 expression delivered by SV40 vectors. J Neuropathol Exp Neurol. 2009 May; 68(5):456-73. PMID: 19525894.
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    31. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 gp120 neurotoxicity proximally and at a distance from the point of exposure: protection by rSV40 delivery of antioxidant enzymes. Neurobiol Dis. 2009 Jun; 34(3):462-76. PMID: 19327399.
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    32. Agrawal L, Maxwell CR, Peters PJ, Clapham PR, Liu SM, Mackay CR, Strayer DS. Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia. J Gen Virol. 2009 Mar; 90(Pt 3):710-722. PMID: 19218218.
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    33. Chan K, Behling E, Strayer DS, Kocher WS, Dessain SK. Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report. J Med Case Rep. 2008 Dec 04; 2:367. PMID: 19055804.
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    34. Louboutin JP, Agrawal L, Liu B, Strayer DS. In vivo gene transfer to the CNS using recombinant SV40-derived vectors. Expert Opin Biol Ther. 2008 Sep; 8(9):1319-35. PMID: 18694352.
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    35. Alton E, Ferrari S, Griesenbach U, Aiuti A, Bachoud-L?vi AC, Blesch A, Brenner MK, Cattaneo F, Chiocca EA, Gao G, High KA, Leen AM, Lemoine NR, McNeish IA, Meneguzzi G, Peschanski M, Roncarolo MG, Strayer DS, Tuszynski MH, Waxman DJ, Wilson JM. Progress and prospects: gene therapy clinical trials (part 2). Gene Ther. 2007 Nov; 14(22):1555-63. PMID: 17984995.
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    36. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. Protecting neurons from HIV-1 gp120-induced oxidant stress using both localized intracerebral and generalized intraventricular administration of antioxidant enzymes delivered by SV40-derived vectors. Gene Ther. 2007 Dec; 14(23):1650-61. PMID: 17914406.
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    37. Louboutin JP, Liu B, Chekmasova AA, Reyes BA, van Bockstaele EJ, Strayer DS. Delivering genes to the organ-localized immune system: long-term results of direct intramarrow transduction. J Gene Med. 2007 Oct; 9(10):843-51. PMID: 17694566.
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    38. Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele E, Strayer DS. Strategies for CNS-directed gene delivery: in vivo gene transfer to the brain using SV40-derived vectors. Gene Ther. 2007 Jun; 14(12):939-49. PMID: 17443215.
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    39. Agrawal L, Louboutin JP, Strayer DS. Preventing HIV-1 Tat-induced neuronal apoptosis using antioxidant enzymes: mechanistic and therapeutic implications. Virology. 2007 Jul 05; 363(2):462-72. PMID: 17336361.
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    40. Strayer DS, Agrawal L, Cordelier P, Liu B, Louboutin JP, Marusich E, McKee HJ, Ren CN, Strayer MS. Long-term gene expression in dividing and nondividing cells using SV40-derived vectors. Mol Biotechnol. 2006 Oct; 34(2):257-70. PMID: 17172671.
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    41. Cordelier P, Bienvenu C, Lulka H, Marrache F, Bouisson M, Openheim A, Strayer DS, Vaysse N, Pradayrol L, Buscail L. Replication-deficient rSV40 mediate pancreatic gene transfer and long-term inhibition of tumor growth. Cancer Gene Ther. 2007 Jan; 14(1):19-29. PMID: 16990845.
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    42. Louboutin JP, Liu B, Reyes BA, Van Bockstaele EJ, Strayer DS. Rat bone marrow progenitor cells transduced in situ by rSV40 vectors differentiate into multiple central nervous system cell lineages. Stem Cells. 2006 Dec; 24(12):2801-9. PMID: 16960137.
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    43. Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. Antioxidant enzyme gene delivery to protect from HIV-1 gp120-induced neuronal apoptosis. Gene Ther. 2006 Dec; 13(23):1645-56. PMID: 16871233.
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    44. Cordelier P, Strayer DS. Using gene delivery to protect HIV-susceptible CNS cells: inhibiting HIV replication in microglia. Virus Res. 2006 Jun; 118(1-2):87-97. PMID: 16414141.
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    45. Liu B, Daviau J, Nichols CN, Strayer DS. In vivo gene transfer into rat bone marrow progenitor cells using rSV40 viral vectors. Blood. 2005 Oct 15; 106(8):2655-62. PMID: 15994284.
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    46. Strayer DS, Akkina R, Bunnell BA, Dropulic B, Planelles V, Pomerantz RJ, Rossi JJ, Zaia JA. Current status of gene therapy strategies to treat HIV/AIDS. Mol Ther. 2005 Jun; 11(6):823-42. PMID: 15922953.
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    47. Strayer DS, Cordelier P, Kondo R, Liu B, Matskevich AA, McKee HJ, Nichols CN, Mitchell CB, Geverd DA, White MK, Strayer MS. What they are, how they work and why they do what they do? The story of SV40-derived gene therapy vectors and what they have to offer. Curr Gene Ther. 2005 Apr; 5(2):151-65. PMID: 15853724.
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    48. Marusich EI, Parveen Z, Strayer D, Mukhtar M, Dornburg RC, Pomerantz RJ. Spleen necrosis virus-based vector delivery of anti-HIV-1 genes potently protects human hematopoietic cells from HIV-1 infection. Virology. 2005 Feb 05; 332(1):258-71. PMID: 15661158.
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    49. Strayer DS, Feitelson M, Sun B, Matskevich AA. Paradigms for conditional expression of RNA interference molecules for use against viral targets. Methods Enzymol. 2005; 392:227-41. PMID: 15644185.
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    50. Sun BS, Pan J, Clayton MM, Liu J, Yan X, Matskevich AA, Strayer DS, Gerber M, Feitelson MA. Hepatitis C virus replication in stably transfected HepG2 cells promotes hepatocellular growth and tumorigenesis. J Cell Physiol. 2004 Dec; 201(3):447-58. PMID: 15389552.
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    51. Cordelier P, Kulkowsky JW, Ko C, Matskevitch AA, McKee HJ, Rossi JJ, Bouhamdan M, Pomerantz RJ, Kari G, Strayer DS. Protecting from R5-tropic HIV: individual and combined effectiveness of a hammerhead ribozyme and a single-chain Fv antibody that targets CCR5. Gene Ther. 2004 Nov; 11(22):1627-37. PMID: 15295615.
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    52. Vera M, Prieto J, Strayer DS, Fortes P. Factors influencing the production of recombinant SV40 vectors. Mol Ther. 2004 Oct; 10(4):780-91. PMID: 15451462.
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    53. Duan YY, Wu J, Zhu JL, Liu SL, Ozaki I, Strayer DS, Zern MA. Gene therapy for human alpha1-antitrypsin deficiency in an animal model using SV40-derived vectors. Gastroenterology. 2004 Oct; 127(4):1222-32. PMID: 15480999.
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    54. McKee HJ, T'sao PY, Vera M, Fortes P, Strayer DS. Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15. Genet Vaccines Ther. 2004 Aug 23; 2(1):10. PMID: 15324456.
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    55. Strayer DS. New technologies in research and diagnosis: implications and opportunities for Human Pathology, its authors, and its readership. Hum Pathol. 2004 Jan; 35(1):1-2. PMID: 14745717.
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    56. Cordelier P, Strayer DS. Conditional expression of alpha1-antitrypsin delivered by recombinant SV40 vectors protects lymphocytes against HIV. Gene Ther. 2003 Dec; 10(26):2153-6. PMID: 14625571.
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    57. Matskevich AA, Cordelier P, Strayer DS. Conditional expression of IFN-alpha and IFN-gamma activated by HBV as genetic therapy for hepatitis B. J Interferon Cytokine Res. 2003 Dec; 23(12):709-21. PMID: 14769147.
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    58. Matskevich AA, Strayer DS. Exploiting hepatitis C virus activation of NFkappaB to deliver HCV-responsive expression of interferons alpha and gamma. Gene Ther. 2003 Oct; 10(22):1861-73. PMID: 14502215.
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    59. Cordelier P, Calarota SA, Pomerantz RJ, Xiaoshan J, Strayer DS. Inhibition of HIV-1 in the central nervous system by IFN-alpha2 delivered by an SV40 vector. J Interferon Cytokine Res. 2003 Sep; 23(9):477-88. PMID: 14565857.
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    60. Cordelier P, Strayer DS. Mechanisms of alpha1-antitrypsin inhibition of cellular serine proteases and HIV-1 protease that are essential for HIV-1 morphogenesis. Biochim Biophys Acta. 2003 Jul 30; 1638(3):197-207. PMID: 12878320.
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    61. Cordelier P, Van Bockstaele E, Calarota SA, Strayer DS. Inhibiting AIDS in the central nervous system: gene delivery to protect neurons from HIV. Mol Ther. 2003 Jun; 7(6):801-10. PMID: 12788654.
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    62. Cordelier P, Zern MA, Strayer DS. HIV-1 proprotein processing as a target for gene therapy. Gene Ther. 2003 Mar; 10(6):467-77. PMID: 12621451.
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    63. Cordelier P, Morse B, Strayer DS. Targeting CCR5 with siRNAs: using recombinant SV40-derived vectors to protect macrophages and microglia from R5-tropic HIV. Oligonucleotides. 2003; 13(5):281-94. PMID: 15000819.
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    64. White MK, Strayer DS. Survival signaling in type II pneumocytes activated by surfactant protein-A. Exp Cell Res. 2002 Nov 01; 280(2):270-9. PMID: 12413892.
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    65. McKee HJ, Strayer DS. Immune responses against SIV envelope glycoprotein, using recombinant SV40 as a vaccine delivery vector. Vaccine. 2002 Oct 04; 20(29-30):3613-25. PMID: 12297408.
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    66. Cordelier P, Calarota SA, Strayer DS. Trans-activated interferon-alpha2 delivered to T cells by SV40 inhibits early stages in the HIV-1 replicative cycle. J Hematother Stem Cell Res. 2002 Oct; 11(5):817-28. PMID: 12427288.
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    67. Strayer D, Branco F, Zern MA, Yam P, Calarota SA, Nichols CN, Zaia JA, Rossi J, Li H, Parashar B, Ghosh S, Chowdhury JR. Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors. Mol Ther. 2002 Aug; 6(2):227-37. PMID: 12161189.
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    68. Strayer DS, Zern MA, Chowdhury JR. What can SV40-derived vectors do for gene therapy? Curr Opin Mol Ther. 2002 Aug; 4(4):313-23. PMID: 12222869.
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    69. Goldstein H, Pettoello-Mantovani M, Anderson CM, Cordelier P, Pomerantz RJ, Strayer DS. Gene therapy using a simian virus 40-derived vector inhibits the development of in vivo human immunodeficiency virus type 1 infection of severe combined immunodeficiency mice implanted with human fetal thymic and liver tissue. J Infect Dis. 2002 May 15; 185(10):1425-30. PMID: 11992277.
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    70. Strayer DS, Branco F, Landr? J, BouHamdan M, Shaheen F, Pomerantz RJ. Combination genetic therapy to inhibit HIV-1. Mol Ther. 2002 Jan; 5(1):33-41. PMID: 11786043.
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    71. Jayan GC, Cordelier P, Patel C, BouHamdan M, Johnson RP, Lisziewicz J, Pomerantz RJ, Strayer DS. SV40-derived vectors provide effective transgene expression and inhibition of HIV-1 using constitutive, conditional,and pol III promoters. Gene Ther. 2001 Jul; 8(13):1033-42. PMID: 11438838.
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    72. BouHamdan M, Strayer DS, Wei D, Mukhtar M, Duan LX, Hoxie J, Pomerantz RJ. Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4. Gene Ther. 2001 Mar; 8(5):408-18. PMID: 11313818.
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    73. White MK, Baireddy V, Strayer DS. Natural protection from apoptosis by surfactant protein A in type II pneumocytes. Exp Cell Res. 2001 Feb 15; 263(2):183-92. PMID: 11161717.
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    74. Strayer DS, Lamothe M, Wei D, Milano J, Kondo R. Generation of recombinant SV40 vectors for gene transfer. Methods Mol Biol. 2001; 165:103-17. PMID: 11217380.
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    75. Sauter BV, Parashar B, Chowdhury NR, Kadakol A, Ilan Y, Singh H, Milano J, Strayer DS, Chowdhury JR. A replication-deficient rSV40 mediates liver-directed gene transfer and a long-term amelioration of jaundice in gunn rats. Gastroenterology. 2000 Nov; 119(5):1348-57. PMID: 11054394.
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    76. Strayer DS. SV40-based gene therapy vectors: turning an adversary into a friend. Curr Opin Mol Ther. 2000 Oct; 2(5):570-8. PMID: 11249759.
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    77. Strayer DS, Korutla L. Activation of surfactant protein-B transcription: signaling through the SP-A receptor utilizing the PI3 kinase pathway. J Cell Physiol. 2000 Aug; 184(2):229-38. PMID: 10867648.
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    78. Strayer DS, Pomerantz RJ, Yu M, Rosenzweig M, BouHamdan M, Yurasov S, Johnson RP, Goldstein H. Efficient gene transfer to hematopoietic progenitor cells using SV40-derived vectors. Gene Ther. 2000 May; 7(10):886-95. PMID: 10845727.
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    79. White MK, Strayer DS. Surfactant protein A regulates pulmonary surfactant secretion via activation of phosphatidylinositol 3-kinase in type II alveolar cells. Exp Cell Res. 2000 Feb 25; 255(1):67-76. PMID: 10666335.
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    80. Strayer DS. Effective gene transfer using viral vectors based on SV40. Methods Mol Biol. 2000; 133:61-74. PMID: 10561831.
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    81. Strayer DS. Gene therapy using SV40-derived vectors: what does the future hold? J Cell Physiol. 1999 Dec; 181(3):375-84. PMID: 10528223.
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    82. Strayer DS. Gene delivery to human hematopoietic progenitor cells to address inherited defects in the erythroid cellular lineage. J Hematother Stem Cell Res. 1999 Dec; 8(6):573-4. PMID: 10645762.
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    83. Strayer DS, Hoek JB, Thomas AP, White MK. Cellular activation by Ca2+ release from stores in the endoplasmic reticulum but not by increased free Ca2+ in the cytosol. Biochem J. 1999 Nov 15; 344 Pt 1:39-46. PMID: 10548531.
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    84. Wali A, Strayer DS. Infection with vaccinia virus alters regulation of cell cycle progression. DNA Cell Biol. 1999 Nov; 18(11):837-43. PMID: 10595397.
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    85. Wali A, Strayer DS. Comparative effects of virulent and avirulent poxviruses on cell cycle progression. Exp Mol Pathol. 1999 Apr; 66(1):31-8. PMID: 10331962.
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    86. BouHamdan M, Duan LX, Pomerantz RJ, Strayer DS. Inhibition of HIV-1 by an anti-integrase single-chain variable fragment (SFv): delivery by SV40 provides durable protection against HIV-1 and does not require selection. Gene Ther. 1999 Apr; 6(4):660-6. PMID: 10476226.
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    87. Korutla L, Strayer DS. SP-A as a cytokine: surfactant protein-A-regulated transcription of surfactant proteins and other genes. J Cell Physiol. 1999 Mar; 178(3):379-86. PMID: 9989784.
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    88. Strayer DS, Foster CS, Gorstein F. Whither human pathology? Hum Pathol. 1999 Jan; 30(1):1-2. PMID: 9923918.
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    89. Zern MA, Ozaki I, Duan L, Pomerantz R, Liu SL, Strayer DS. A novel SV40-based vector successfully transduces and expresses an alpha 1-antitrypsin ribozyme in a human hepatoma-derived cell line. Gene Ther. 1999 Jan; 6(1):114-20. PMID: 10341883.
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    90. Strayer DS, Zern MA. Gene delivery to the liver using simian virus 40-derived vectors. Semin Liver Dis. 1999; 19(1):71-81. PMID: 10349685.
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    91. Chen Q, Fisher AB, Strayer DS, Bates SR. Mechanism for secretagogue-induced surfactant protein A binding to lung epithelial cells. Am J Physiol. 1998 07; 275(1):L38-46. PMID: 9688933.
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    92. Strayer DS. Viral vectors for gene therapy: past, present and future. Drug News Perspect. 1998 Jun; 11(5):277-86. PMID: 15616647.
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    93. Kondo R, Feitelson MA, Strayer DS. Use of SV40 to immunize against hepatitis B surface antigen: implications for the use of SV40 for gene transduction and its use as an immunizing agent. Gene Ther. 1998 May; 5(5):575-82. PMID: 9797861.
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    94. Milano J, Strayer DS. Effects of overexpression of Ran/TC4 mammalian cells in vitro. Exp Cell Res. 1998 Feb 25; 239(1):31-9. PMID: 9511722.
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    95. Herting E, Strayer DS, Jarstrand C, Sun B, Robertson B. Lung function and bacterial proliferation in experimental neonatal pneumonia in ventilated rabbits exposed to monoclonal antibody to surfactant protein A. Lung. 1998; 176(2):123-31. PMID: 9500297.
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    96. Strayer DS, Schwarting R. Recognition of normal, neoplastic, and fetal airway epithelial cell membranes by two monoclonal antibodies. Hum Pathol. 1997 Jul; 28(7):840-6. PMID: 9224754.
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    97. Strayer DS, Duan LX, Ozaki I, Milano J, Bobraski LE, Bagasra O. Titering replication-defective virus for use in gene transfer. Biotechniques. 1997 Mar; 22(3):447-50. PMID: 9067019.
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    98. Strayer DS, Kondo R, Milano J, Duan LX. Use of SV40-based vectors to transduce foreign genes to normal human peripheral blood mononuclear cells. Gene Ther. 1997 Mar; 4(3):219-25. PMID: 9135735.
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    99. Strayer DS, Korutla L, Thomas AP. Surfactant protein-A receptor-mediated inhibition of calcium signaling in alveolar type II cells. Recept Signal Transduct. 1997; 7(2):111-20. PMID: 9392439.
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    100. Strayer DS. SV40 as an effective gene transfer vector in vivo. J Biol Chem. 1996 Oct 04; 271(40):24741-6. PMID: 8798743.
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    101. Wali A, Strayer DS. Regulation of p53 gene expression by a poxviral transcription factor. Virology. 1996 Oct 01; 224(1):63-72. PMID: 8862400.
      Citations:    
    102. Strayer DS, Pinder R, Chander A. Receptor-mediated regulation of pulmonary surfactant secretion. Exp Cell Res. 1996 Jul 10; 226(1):90-7. PMID: 8660943.
      Citations:    
    103. Strayer DS, Milano J. SV40 mediates stable gene transfer in vivo. Gene Ther. 1996 Jul; 3(7):581-7. PMID: 8818644.
      Citations:    
    104. Strayer DS, Herting E, Sun B, Robertson B. Antibody to surfactant protein A increases sensitivity of pulmonary surfactant to inactivation by fibrinogen in vivo. Am J Respir Crit Care Med. 1996 Mar; 153(3):1116-22. PMID: 8630554.
      Citations:    
    105. Luzi P, Anceschi M, Strayer DS. The upstream region of the SP-B gene: intrinsic promoter activity and glucocorticoid responsiveness related to a new DNA-binding protein. Gene. 1995 Nov 20; 165(2):285-90. PMID: 8522191.
      Citations:    
    106. Luzi P, Strayer DS. DNA binding proteins that amplify surfactant protein B gene expression: isolation and characterization. Biochem Biophys Res Commun. 1995 Mar 08; 208(1):153-60. PMID: 7887923.
      Citations:    
    107. Strayer DS, Merritt TA, Hallman M. Levels of SP-A-anti-SP-A immune complexes in neonatal respiratory distress syndrome correlate with subsequent development of bronchopulmonary dysplasia. Acta Paediatr. 1995 Feb; 84(2):128-31. PMID: 7756795.
      Citations:    
    108. Luzi P, Anceschi M, Strayer DS. Glucocorticoid responsiveness conferred by a cloned DNA binding protein. Receptor. 1995; 5(2):93-103. PMID: 7580940.
      Citations:    
    109. Strayer DS. The viruses don't always read the books: engineered vaccines and gene therapy using viral vectors. Lab Invest. 1994 Sep; 71(3):319-23. PMID: 7933983.
      Citations:    
    110. Gillespie D, Hubbell HR, Carter WA, Midgette P, Elsasser W, Mullaney R, Strayer DR. Synergistic inhibition of AZT-resistant HIV by AZT combined with poly(I):poly(C12U), without synergistic toxicity to bone marrow progenitor cell elements. In Vivo. 1994 May-Jun; 8(3):375-81. PMID: 7803722.
      Citations:    
    111. Spragg RG, Gilliard N, Richman P, Smith RM, Hite RD, Pappert D, Robertson B, Curstedt T, Strayer D. Acute effects of a single dose of porcine surfactant on patients with the adult respiratory distress syndrome. Chest. 1994 Jan; 105(1):195-202. PMID: 8031347.
      Citations:    
    112. Strayer DS, Yang S, Schwartz MS. Epidermal growth factor-like growth factors. I. Breast malignancies and other epithelial proliferations in transgenic mice. Lab Invest. 1993 Dec; 69(6):660-73. PMID: 8264229.
      Citations:    
    113. Strayer DS. Effect of virus infection on levels of transcripts for cellular genes. Virus Res. 1993 Dec; 30(3):259-69. PMID: 8109159.
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    114. Strayer DS, Yang S, Jerng HH. Surfactant protein A-binding proteins. Characterization and structures. J Biol Chem. 1993 Sep 05; 268(25):18679-84. PMID: 8360162.
      Citations:    
    115. Strayer DS, Mathew J. A 34-kd protein with strong homology to ras-like proteins inhibits epidermal growth factor activity. Am J Pathol. 1993 Apr; 142(4):1141-53. PMID: 8475991.
      Citations:    
    116. Strayer DS, Jerng HH. Sequence and analysis of the BamHI "D" fragment of Shope fibroma virus: comparison with similar regions of related poxviruses. Virus Res. 1992 Sep 01; 25(1-2):117-32. PMID: 1329373.
      Citations:    
    117. Opgenorth A, Graham K, Nation N, Strayer D, McFadden G. Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factor. J Virol. 1992 Aug; 66(8):4720-31. PMID: 1629952.
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    118. Robertson B, Curstedt T, Tubman R, Strayer D, Berggren P, Kok J, Koppe J, van Sonderen L, Halliday H, McClure G, et al. A 2-year follow up of babies enrolled in a European multicentre trial of porcine surfactant replacement for severe neonatal respiratory distress syndrome. Collaborative European Multicentre Study Group. Eur J Pediatr. 1992 May; 151(5):372-6. PMID: 1396894.
      Citations:    
    119. Strayer DS, Robertson B. Surfactant as an immunogen: implications for therapy of respiratory distress syndrome. Acta Paediatr. 1992 May; 81(5):446-7. PMID: 1498516.
      Citations:    
    120. Strayer DS. Applications of anti-curosurf antibodies to understanding the biology of alveolar surfactant. Biol Neonate. 1992; 61 Suppl 1:2-14. PMID: 1327194.
      Citations:    
    121. Strayer DS. Determinants of virus-related suppression of immune responses as observed during infection with an oncogenic poxvirus. Prog Med Virol. 1992; 39:228-55. PMID: 1317599.
      Citations:    
    122. Opgenorth A, Strayer D, Upton C, McFadden G. Deletion of the growth factor gene related to EGF and TGF alpha reduces virulence of malignant rabbit fibroma virus. Virology. 1992 Jan; 186(1):175-91. PMID: 1309274.
      Citations:    
    123. Strayer DS, Jerng HH, O'Connor K. Sequence and analysis of a portion of the genomes of Shope fibroma virus and malignant rabbit fibroma virus that is important for viral replication in lymphocytes. Virology. 1991 Dec; 185(2):585-95. PMID: 1660196.
      Citations:    
    124. Eijking EP, Strayer DS, van Daal GJ, Tenbrinck R, Merritt TA, Hannappel E, Lachmann B. In vivo and in vitro inactivation of bovine surfactant by an anti-surfactant monoclonal antibody. Eur Respir J. 1991 Nov; 4(10):1245-50. PMID: 1804672.
      Citations:    
    125. Strayer DS. Identification of a cell membrane protein that binds alveolar surfactant. Am J Pathol. 1991 May; 138(5):1085-95. PMID: 1850959.
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    126. Strayer DS, Hallman M, Merritt TA. Immunogenicity of surfactant. I. Human alveolar surfactant. Clin Exp Immunol. 1991 Jan; 83(1):35-40. PMID: 1988229.
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    127. Strayer DS, Hallman M, Merritt TA. Immunogenicity of surfactant. II. Porcine and bovine surfactants. Clin Exp Immunol. 1991 Jan; 83(1):41-6. PMID: 1988231.
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    128. Eijking EP, Strayer DS, van Daal GJ, Lachmann B. Effects of antisurfactant antibodies on the course of mild respiratory distress syndrome. Pathobiology. 1991; 59(2):96-101. PMID: 1907454.
      Citations:    
    129. Strayer DS, Laybourn KA, Heard HK. Determinants of the ability of malignant fibroma virus to induce immune dysfunction and tumor dissemination in vivo. Microb Pathog. 1990 Sep; 9(3):173-89. PMID: 1964998.
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    130. Laybourn KA, Hiserodt JC, Hunt JM, Sell S, Strayer DS. Natural cell-mediated immunity in the rabbit. Cell Immunol. 1990 Sep; 129(2):519-27. PMID: 2383903.
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    131. Heard HK, O'Connor K, Strayer DS. Molecular analysis of immunosuppression induced by virus replication in lymphocytes. J Immunol. 1990 May 15; 144(10):3992-9. PMID: 2159037.
      Citations:    
    132. Strayer DS, Merritt TA, Makunike C, Hallman M. Antigenicity of low molecular weight surfactant species. Am J Pathol. 1989 Apr; 134(4):723-32. PMID: 2705504.
      Citations:    
    133. Strayer DS, Merritt TA, Hallman M. Surfactant replacement: immunological considerations. Eur Respir J Suppl. 1989 Mar; 3:91s-96s. PMID: 2742687.
      Citations:    
    134. Strayer DS, Dombrowski J. Immunosuppression during viral oncogenesis. V. Resistance to virus-induced immunosuppressive factor. J Immunol. 1988 Jul 01; 141(1):347-51. PMID: 2837511.
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    135. Merritt TA, Strayer DS, Hallman M, Spragg RD, Wozniak P. Immunologic consequences of exogenous surfactant administration. Semin Perinatol. 1988 Jul; 12(3):221-30. PMID: 3041605.
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    136. Strayer DS, Mulloy J, Leibowitz JL. Lymphocyte-virus interactions. Identification of a restriction fragment permitting virus replication in lymphocytes. J Immunol. 1988 Mar 15; 140(6):2060-7. PMID: 2894396.
      Citations:    
    137. Strayer DS, Korber K, Dombrowski J. Immunosuppression during viral oncogenesis. IV. Generation of soluble virus-induced immunologic suppressor molecules. J Immunol. 1988 Mar 15; 140(6):2051-9. PMID: 2831278.
      Citations:    
    138. Strayer DS, Leibowitz JL. Inhibition of epidermal growth factor-induced cellular proliferation. Am J Pathol. 1987 Aug; 128(2):203-9. PMID: 3039847.
      Citations:    
    139. Strayer DS, Skaletsky E, Leibowitz JL, Dombrowski J. Growth of malignant rabbit fibroma virus in lymphoid cells. Virology. 1987 May; 158(1):147-57. PMID: 3033886.
      Citations:    
    140. Strayer DS, Leibowitz JL. Virus-lymphocyte interactions during the course of immunosuppressive virus infection. J Gen Virol. 1987 Feb; 68 ( Pt 2):463-72. PMID: 3029285.
      Citations:    
    141. Strayer DS, Horowitz M, Leibowitz JL. Immunosuppression in viral oncogenesis. III. Effects of virus infection on interleukin 1 and interleukin 2 generation and responsiveness. J Immunol. 1986 Dec 01; 137(11):3632-8. PMID: 3023485.
      Citations:    
    142. Strayer DS, Skaletsky E, Leibowitz JL. Inhibition of virus replication does not alter malignant rabbit fibroma virus-induced immunosuppression. Clin Exp Immunol. 1986 Oct; 66(1):25-36. PMID: 3026700.
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    143. Cabirac GF, Mulloy JJ, Strayer DS, Sell S, Leibowitz JL. Transcriptional mapping of early RNA from regions of the Shope fibroma and malignant rabbit fibroma virus genomes. Virology. 1986 Aug; 153(1):53-69. PMID: 3016986.
      Citations:    
    144. Merritt TA, Hallman M, Holcomb K, Strayer D, Bloom B, Revak S, Cochrane CG. Human surfactant treatment of severe respiratory distress syndrome: pulmonary effluent indicators of lung inflammation. J Pediatr. 1986 May; 108(5 Pt 1):741-8. PMID: 3486264.
      Citations:    
    145. Strayer DS, Leibowitz JL. Reversal of virus-induced immune suppression. J Immunol. 1986 Apr 01; 136(7):2649-53. PMID: 3005416.
      Citations:    
    146. Strayer DS, Merritt TA, Lwebuga-Mukasa J, Hallman M. Surfactant-anti-surfactant immune complexes in infants with respiratory distress syndrome. Am J Pathol. 1986 Feb; 122(2):353-62. PMID: 3511728.
      Citations:    
    147. Sell S, Strayer D, Skaletsky E, Corbeil L, Cabirac G, Leibowitz J. Leporine acquired immune deficiency disease. Symp Fundam Cancer Res. 1986; 38:97-111. PMID: 3018882.
      Citations:    
    148. Strayer DS, Skaletsky E, Leibowitz JL. In vitro growth of two related leporipoxviruses in lymphoid cells. Virology. 1985 Sep; 145(2):330-4. PMID: 2992155.
      Citations:    
    149. Strayer DS, Sell S, Leibowitz JL. Malignant rabbit fibroma syndrome. A possible model for acquired immunodeficiency syndrome (AIDS). Am J Pathol. 1985 Jul; 120(1):170-1. PMID: 2990222.
      Citations:    
    150. Cabirac GF, Strayer DS, Sell S, Leibowitz JL. Characterization, molecular cloning, and physical mapping of the Shope fibroma virus genome. Virology. 1985 Jun; 143(2):663-70. PMID: 2998033.
      Citations:    
    151. Strayer DS, Skaletsky E, Sell S. Strain differences in Shope fibroma virus. An immunopathologic study. Am J Pathol. 1984 Aug; 116(2):342-58. PMID: 6087669.
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    152. Skaletsky E, Sharp PA, Sell S, Strayer DS. Immunologic dysfunction during viral oncogenesis. II. Inhibition of cellular immunity to viral antigens by malignant rabbit fibroma virus. Cell Immunol. 1984 Jun; 86(1):64-74. PMID: 6327086.
      Citations:    
    153. Strayer DS, Sell S, Skaletsky E, Leibowitz JL. Immunologic dysfunction during viral oncogenesis. I. Nonspecific immunosuppression caused by malignant rabbit fibroma virus. J Immunol. 1983 Nov; 131(5):2595-600. PMID: 6195270.
      Citations:    
    154. Merritt TA, Cochrane CG, Holcomb K, Bohl B, Hallman M, Strayer D, Edwards DK, Gluck L. Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasia. J Clin Invest. 1983 Aug; 72(2):656-66. PMID: 6603478.
      Citations:    
    155. Strayer D, Heintz N, Roeder R, Gillespie D. Three organizations of human DNA. Proc Natl Acad Sci U S A. 1983 Aug; 80(15):4770-4. PMID: 6576359.
      Citations:    
    156. Strayer DS, Sell S. Immunohistology of malignant rabbit fibroma virus--a comparative study with rabbit myxoma virus. J Natl Cancer Inst. 1983 Jul; 71(1):105-16. PMID: 6306322.
      Citations:    
    157. Strayer DS, Cabirac G, Sell S, Leibowitz JL. Malignant rabbit fibroma virus: observations on the culture and histopathologic characteristics of a new virus-induced rabbit tumor. J Natl Cancer Inst. 1983 Jul; 71(1):91-104. PMID: 6306326.
      Citations:    
    158. Merritt TA, Cochrane CG, Hallman M, Holcomb KE, Strayer D, Mannino F, Edwards DK, Gluck L. Reduction of lung injury by human surfactant treatment in respiratory distress syndrome. Chest. 1983 May; 83(5 Suppl):27S-31S. PMID: 6601570.
      Citations:    
    159. Corbeil LB, Strayer DS, Skaletsky E, Wunderlich A, Sell S. Immunity to pasteurellosis in compromised rabbits. Am J Vet Res. 1983 May; 44(5):845-50. PMID: 6307088.
      Citations:    
    160. Strayer DS, Skaletsky E, Cabirac GF, Sharp PA, Corbeil LB, Sell S, Leibowitz JL. Malignant rabbit fibroma virus causes secondary immunosuppression in rabbits. J Immunol. 1983 Jan; 130(1):399-404. PMID: 6292305.
      Citations:    
    161. Santa Cruz DJ, Strayer DS. The histologic spectrum of the cutaneous mycobacterioses. Hum Pathol. 1982 May; 13(5):485-95. PMID: 6804365.
      Citations:    
    162. Gillespie D, Gaspari M, Strayer D. Addition of deoxynucleotides to an RNA primer by a DNA polymerase in human platelets. Biochem Biophys Res Commun. 1981 Apr 30; 99(4):1191-8. PMID: 6167266.
      Citations:    
    163. Gillespie D, Pequignot E, Strayer D. An ancestral amplification of DNA in primates. Gene. 1980 Dec; 12(1-2):103-11. PMID: 7215800.
      Citations:    
    164. Nelkin B, Strayer D, Vogelstein B. Divergence of primate ribosomal RNA genes as assayed by restriction enzyme analysis. Gene. 1980 Oct; 11(1-2):89-96. PMID: 6254856.
      Citations:    
    165. Kapp JA, Strayer DS, Robbins PF, Perlmutter RM. Insulin-specific murine antibodies of limited heterogeneity. I. Genetic control of spectrotypes. J Immunol. 1979 Jul; 123(1):109-14. PMID: 448141.
      Citations:    
    166. Strayer DS, Kissane JM. Dysplasia of the kidneys, liver, and pancreas: report of a variant of Ivemark's syndrome. Hum Pathol. 1979 Mar; 10(2):228-34. PMID: 422192.
      Citations:    
    167. Kapp JA, Strayer DS. H-2 linked Ir gene control of antibody responses to porcine insulin. I. Development of insulin-specific antibodies in some but not all nonresponder strains injected with proinsulin. J Immunol. 1978 Sep; 121(3):978-82. PMID: 690445.
      Citations:    
    168. Strayer DS, Lee WM, Rowley DA, K?hler H. Anti-receptor antibody. II. Induction of long-term unresponsiveness in neonatal mice. J Immunol. 1975 Feb; 114(2 pt 2):728-33. PMID: 46888.
      Citations:    
    169. K?hler H, Kaplan DR, Strayer DS. Clonal depletion in neonatal tolerance. Science. 1974 Nov 15; 186(4164):643-4. PMID: 4137580.
      Citations:    
    170. Strayer DS, Cosenza H, Lee WM, Rowley DA, K?hler H. Neonatal tolerance induced by antibody against antigen-specific receptor. Science. 1974 Nov 15; 186(4164):640-3. PMID: 4137861.
      Citations:    
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