Thomas Jefferson University

David Abraham

TitleAssoc Dean
InstitutionThomas Jefferson University
DepartmentSKMC - Senior Administration
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-8917
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Navi A, Patel H, Shiwen X, Baker D, Abraham D, Tsui J. Role of toll-like receptor 4 in skeletal muscle damage in chronic limb-threatening ischemia. JVS Vasc Sci. 2024; 5:100194. PMID: 38510939.
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    2. Moezinia C, Wong V, Watson J, Nagib L, Lopez Garces S, Zhang S, Ahmed Abdi B, Newton F, Abraham D, Stratton R. Autoantibodies Which Bind to and Activate Keratinocytes in Systemic Sclerosis. Cells. 2023 10 20; 12(20). PMID: 37887334.
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    3. Ryan NM, Hess JA, Robertson EJ, Tricoche N, Turner C, Davis J, Petrovsky N, Ferguson M, Rinaldi WJ, Wong VM, Shimada A, Zhan B, Bottazzi ME, Makepeace BL, Gray SA, Carter D, Lustigman S, Abraham D. Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates. Vaccines (Basel). 2023 Jul 06; 11(7). PMID: 37515028.
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    4. Hess JA, Eberhard ML, Segura-Lepe M, Grundner-Culemann K, Kracher B, Shryock J, Harrington J, Abraham D. A rodent model for Dirofilaria immitis, canine heartworm: parasite growth, development, and drug sensitivity in NSG mice. Sci Rep. 2023 01 18; 13(1):976. PMID: 36653420.
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    5. Herbert DR, Stoltzfus JDC, Rossi HL, Abraham D. Is Strongyloides stercoralis hyperinfection induced by glucocorticoids a result of both suppressed host immunity and altered parasite genetics? Mol Biochem Parasitol. 2022 09; 251:111511. PMID: 36007683.
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    6. Luu L, Bah GS, Okah-Nnane NH, Hartley CS, Glover AF, Walsh TR, Lian LY, Zhan B, Bottazzi ME, Abraham D, Petrovsky N, Bayang N, Tangwa B, Ayiseh RB, Mbah GE, Ekale DD, Tanya VN, Lustigman S, Makepeace BL, Graham-Brown J. Co-Administration of Adjuvanted Recombinant Ov-103 and Ov-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine Onchocerca ochengi Infection Model of Human Onchocerciasis. Vaccines (Basel). 2022 May 27; 10(6). PMID: 35746469.
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    7. Berg K, Wilson A, Day K, Abraham D, Herrine S. Progression Toward a Competency-Based Assessment Paradigm. Acad Med. 2021 11 01; 96(11S):S176-S177. PMID: 34705674.
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    8. Abraham D, Graham-Brown J, Carter D, Gray SA, Hess JA, Makepeace BL, Lustigman S. Development of a recombinant vaccine against human onchocerciasis. Expert Rev Vaccines. 2021 Nov; 20(11):1459-1470. PMID: 34488533.
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    9. Springer LE, Patton JB, Zhan T, Rabson AB, Lin HC, Manser T, Lok JB, Hess JA, Abraham D. Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth. PLoS Negl Trop Dis. 2021 07; 15(7):e0009559. PMID: 34314415.
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    10. Tam AYY, Horwell AL, Trinder SL, Khan K, Xu S, Ong V, Denton CP, Norman JT, Holmes AM, Bou-Gharios G, Abraham DJ. Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension. Int J Biochem Cell Biol. 2021 05; 134:105961. PMID: 33662577.
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    11. Ryan NM, Hess JA, de Villena FP, Leiby BE, Shimada A, Yu L, Yarmahmoodi A, Petrovsky N, Zhan B, Bottazzi ME, Makepeace BL, Lustigman S, Abraham D. Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice. NPJ Vaccines. 2021 Jan 26; 6(1):17. PMID: 33500417.
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    12. Dykie A, Wijesinghe T, Rabson AB, Madugula K, Farinas C, Wilson S, Abraham D, Jain P. Human T-cell Leukemia Virus Type 1 and Strongyloides stercoralis: Partners in Pathogenesis. Pathogens. 2020 Oct 29; 9(11). PMID: 33137906.
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    13. Portou MJ, Yu R, Baker D, Xu S, Abraham D, Tsui J. Hyperglycaemia and Ischaemia Impair Wound Healing via Toll-like Receptor 4 Pathway Activation in vitro and in an Experimental Murine Model. Eur J Vasc Endovasc Surg. 2020 Jan; 59(1):117-127. PMID: 31732468.
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    14. George PJ, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans. PLoS Negl Trop Dis. 2019 09; 13(9):e0007730. PMID: 31525197.
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    15. Patton JB, Bennuru S, Eberhard ML, Hess JA, Torigian A, Lustigman S, Nutman TB, Abraham D. Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. PLoS Negl Trop Dis. 2018 12; 12(12):e0006977. PMID: 30540742.
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    16. Patton JB, Bonne-Ann?e S, Deckman J, Hess JA, Torigian A, Nolan TJ, Wang Z, Kliewer SA, Durham AC, Lee JJ, Eberhard ML, Mangelsdorf DJ, Lok JB, Abraham D. Methylprednisolone acetate induces, and ?7-dafachronic acid suppresses, Strongyloides stercoralis hyperinfection in NSG mice. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):204-209. PMID: 29203662.
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    17. Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME. Onchocerca volvulus: The Road from Basic Biology to a Vaccine. Trends Parasitol. 2018 01; 34(1):64-79. PMID: 28958602.
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    18. Bennuru S, Lustigman S, Abraham D, Nutman TB. Metabolite profiling of infection-associated metabolic markers of onchocerciasis. Mol Biochem Parasitol. 2017 07; 215:58-69. PMID: 28188804.
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    19. Ahadome SD, Abraham DJ, Rayapureddi S, Saw VP, Saban DR, Calder VL, Norman JT, Ponticos M, Daniels JT, Dart JK. Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring. JCI Insight. 2016 08 04; 1(12):e87001. PMID: 27699226.
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    20. Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice. PLoS Negl Trop Dis. 2016 07; 10(7):e0004797. PMID: 27387453.
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    21. Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004586. PMID: 27045170.
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    22. Breloer M, Abraham D. Strongyloides infection in rodents: immune response and immune regulation. Parasitology. 2017 03; 144(3):295-315. PMID: 26905057.
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    23. Behmoaras J, Diaz AG, Venda L, Ko JH, Srivastava P, Montoya A, Faull P, Webster Z, Moyon B, Pusey CD, Abraham DJ, Petretto E, Cook TH, Aitman TJ. Macrophage epoxygenase determines a profibrotic transcriptome signature. J Immunol. 2015 May 15; 194(10):4705-4716. PMID: 25840911.
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    24. Hotez PJ, Bottazzi ME, Zhan B, Makepeace BL, Klei TR, Abraham D, Taylor DW, Lustigman S. The Onchocerciasis Vaccine for Africa--TOVA--Initiative. PLoS Negl Trop Dis. 2015 Jan; 9(1):e0003422. PMID: 25634641.
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    25. Arumugam S, Wei J, Ward D, Abraham D, Lustigman S, Zhan B, Klei TR. Vaccination with a genetically modified Brugia malayi cysteine protease inhibitor-2 reduces adult parasite numbers and affects the fertility of female worms following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae. Int J Parasitol. 2014 Sep; 44(10):675-9. PMID: 24929131.
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    26. Hess JA, Zhan B, Bonne-Ann?e S, Deckman JM, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model. Int J Parasitol. 2014 Aug; 44(9):637-46. PMID: 24907553.
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    27. Bonne-Ann?e S, Kerepesi LA, Hess JA, Wesolowski J, Paumet F, Lok JB, Nolan TJ, Abraham D. Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis. Microbes Infect. 2014 Jun; 16(6):502-11. PMID: 24642003.
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    28. Arumugam S, Zhan B, Abraham D, Ward D, Lustigman S, Klei TR. Vaccination with recombinant Brugia malayi cystatin proteins alters worm migration, homing and final niche selection following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae. Parasit Vectors. 2014 Jan 22; 7:43. PMID: 24450869.
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    29. Derrett-Smith EC, Dooley A, Gilbane AJ, Trinder SL, Khan K, Baliga R, Holmes AM, Hobbs AJ, Abraham D, Denton CP. Endothelial injury in a transforming growth factor ?-dependent mouse model of scleroderma induces pulmonary arterial hypertension. Arthritis Rheum. 2013 Nov; 65(11):2928-39. PMID: 23839959.
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    30. Bonne-Ann?e S, Kerepesi LA, Hess JA, O'Connell AE, Lok JB, Nolan TJ, Abraham D. Human and mouse macrophages collaborate with neutrophils to kill larval Strongyloides stercoralis. Infect Immun. 2013 Sep; 81(9):3346-55. PMID: 23798541.
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    31. Krolewiecki AJ, Lammie P, Jacobson J, Gabrielli AF, Levecke B, Socias E, Arias LM, Sosa N, Abraham D, Cimino R, Echaz? A, Crudo F, Vercruysse J, Albonico M. A public health response against Strongyloides stercoralis: time to look at soil-transmitted helminthiasis in full. PLoS Negl Trop Dis. 2013; 7(5):e2165. PMID: 23675541.
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    32. Sonnylal S, Xu S, Jones H, Tam A, Sreeram VR, Ponticos M, Norman J, Agrawal P, Abraham D, de Crombrugghe B. Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro. J Cell Sci. 2013 May 15; 126(Pt 10):2164-75. PMID: 23525012.
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    33. Bonne-Ann?e S, Hess JA, Abraham D. Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model. Immunol Res. 2011 Dec; 51(2-3):205-14. PMID: 22101674.
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    34. Colombo MJ, Abraham D, Shibuya A, Alugupalli KR. B1b lymphocyte-derived antibodies control Borrelia hermsii independent of Fca/? receptor and in the absence of host cell contact. Immunol Res. 2011 Dec; 51(2-3):249-56. PMID: 22139824.
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    35. Abraham D, Hess JA, Mejia R, Nolan TJ, Lok JB, Lustigman S, Nutman TB. Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice. Vaccine. 2011 Oct 19; 29(45):8134-40. PMID: 21856350.
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    36. Ramanathan R, Varma S, Ribeiro JM, Myers TG, Nolan TJ, Abraham D, Lok JB, Nutman TB. Microarray-based analysis of differential gene expression between infective and noninfective larvae of Strongyloides stercoralis. PLoS Negl Trop Dis. 2011 May 03; 5(5):e1039. PMID: 21572524.
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    37. O'Connell AE, Hess JA, Santiago GA, Nolan TJ, Lok JB, Lee JJ, Abraham D. Major basic protein from eosinophils and myeloperoxidase from neutrophils are required for protective immunity to Strongyloides stercoralis in mice. Infect Immun. 2011 Jul; 79(7):2770-8. PMID: 21482685.
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    38. O'Connell AE, Redding KM, Hess JA, Lok JB, Nolan TJ, Abraham D. Soluble extract from the nematode Strongyloides stercoralis induces CXCR2 dependent/IL-17 independent neutrophil recruitment. Microbes Infect. 2011 Jun; 13(6):536-44. PMID: 21315175.
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    39. McCann MR, Monemdjou R, Ghassemi-Kakroodi P, Fahmi H, Perez G, Liu S, Shi-Wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M. mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis. Arthritis Res Ther. 2011; 13(1):R6. PMID: 21266028.
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    40. Liu S, Shi-wen X, Abraham DJ, Leask A. CCN2 is required for bleomycin-induced skin fibrosis in mice. Arthritis Rheum. 2011 Jan; 63(1):239-46. PMID: 20936632.
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    41. Liu S, Xu SW, Blumbach K, Eastwood M, Denton CP, Eckes B, Krieg T, Abraham DJ, Leask A. Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo. J Cell Sci. 2010 Nov 01; 123(Pt 21):3674-82. PMID: 20940256.
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    42. Krolewiecki AJ, Ramanathan R, Fink V, McAuliffe I, Cajal SP, Won K, Juarez M, Di Paolo A, Tapia L, Acosta N, Lee R, Lammie P, Abraham D, Nutman TB. Improved diagnosis of Strongyloides stercoralis using recombinant antigen-based serologies in a community-wide study in northern Argentina. Clin Vaccine Immunol. 2010 Oct; 17(10):1624-30. PMID: 20739501.
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    43. Hoyles RK, Derrett-Smith EC, Khan K, Shiwen X, Howat SL, Wells AU, Abraham DJ, Denton CP. An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor ? receptor. Am J Respir Crit Care Med. 2011 Jan 15; 183(2):249-61. PMID: 20709822.
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    44. Sonnylal S, Shi-Wen X, Leoni P, Naff K, Van Pelt CS, Nakamura H, Leask A, Abraham D, Bou-Gharios G, de Crombrugghe B. Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. Arthritis Rheum. 2010 May; 62(5):1523-32. PMID: 20213804.
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    45. Derrett-Smith EC, Dooley A, Khan K, Shi-wen X, Abraham D, Denton CP. Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma. Arthritis Res Ther. 2010; 12(2):R69. PMID: 20398328.
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    46. O'Connell AE, Kerepesi LA, Vandergrift GL, Herbert DR, VAN Winkle TJ, Hooper DC, Pearce EJ, Abraham D. IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages. Parasite Immunol. 2009 Dec; 31(12):741-9. PMID: 19891612.
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    47. Liu S, Kapoor M, Denton CP, Abraham DJ, Leask A. Loss of beta1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model. Arthritis Rheum. 2009 Sep; 60(9):2817-21. PMID: 19714619.
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    48. Kapoor M, McCann M, Liu S, Huh K, Denton CP, Abraham DJ, Leask A. Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis. Arthritis Rheum. 2009 Sep; 60(9):2822-9. PMID: 19714649.
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    49. Stein LH, Redding KM, Lee JJ, Nolan TJ, Schad GA, Lok JB, Abraham D. Eosinophils utilize multiple chemokine receptors for chemotaxis to the parasitic nematode Strongyloides stercoralis. J Innate Immun. 2009; 1(6):618-30. PMID: 20375616.
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    50. Ponticos M, Holmes AM, Shi-wen X, Leoni P, Khan K, Rajkumar VS, Hoyles RK, Bou-Gharios G, Black CM, Denton CP, Abraham DJ, Leask A, Lindahl GE. Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen. Arthritis Rheum. 2009 Jul; 60(7):2142-55. PMID: 19565505.
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    51. Alugupalli KR, Abraham D. B cell multitasking is required to control nematode infection. Immunity. 2009 Mar 20; 30(3):317-9. PMID: 19303384.
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    52. Kapoor M, Liu S, Shi-wen X, Huh K, McCann M, Denton CP, Woodgett JR, Abraham DJ, Leask A. GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism. J Clin Invest. 2008 Oct; 118(10):3279-90. PMID: 18802478.
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    53. Liu S, Kapoor M, Shi-wen X, Kennedy L, Denton CP, Glogauer M, Abraham DJ, Leask A. Role of Rac1 in a bleomycin-induced scleroderma model using fibroblast-specific Rac1-knockout mice. Arthritis Rheum. 2008 Jul; 58(7):2189-95. PMID: 18576327.
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    54. Hoyles RK, Khan K, Shiwen X, Howat SL, Lindahl GE, Leoni P, du Bois RM, Wells AU, Black CM, Abraham DJ, Denton CP. Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model. Arthritis Rheum. 2008 Apr; 58(4):1175-88. PMID: 18383385.
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    55. Padigel UM, Hess JA, Lee JJ, Lok JB, Nolan TJ, Schad GA, Abraham D. Eosinophils act as antigen-presenting cells to induce immunity to Strongyloides stercoralis in mice. J Infect Dis. 2007 Dec 15; 196(12):1844-51. PMID: 18190266.
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    56. Sinagra A, Luna C, Abraham D, Iannella Mdel C, Riarte A, Krolewiecki AJ. The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis in the golden hamster model. Rev Soc Bras Med Trop. 2007 Nov-Dec; 40(6):627-30. PMID: 18200413.
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    57. Krolewiecki AJ, Romero HD, Cajal SP, Abraham D, Mimori T, Matsumoto T, Juarez M, Taranto NJ. A randomized clinical trial comparing oral azithromycin and meglumine antimoniate for the treatment of American cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis. Am J Trop Med Hyg. 2007 Oct; 77(4):640-6. PMID: 17978064.
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    58. Padigel UM, Stein L, Redding K, Lee JJ, Nolan TJ, Schad GA, Birnbaumer L, Abraham D. Signaling through Galphai2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. J Leukoc Biol. 2007 Apr; 81(4):1120-6. PMID: 17242370.
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    59. Kennedy L, Liu S, Shi-Wen X, Chen Y, Eastwood M, Sabetkar M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res. 2007 Mar 10; 313(5):952-64. PMID: 17239853.
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    60. Kerepesi LA, Hess JA, Leon O, Nolan TJ, Schad GA, Abraham D. Toll-like receptor 4 (TLR4) is required for protective immunity to larval Strongyloides stercoralis in mice. Microbes Infect. 2007 Jan; 9(1):28-34. PMID: 17196865.
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    61. Galioto AM, Hess JA, Nolan TJ, Schad GA, Lee JJ, Abraham D. Role of eosinophils and neutrophils in innate and adaptive protective immunity to larval strongyloides stercoralis in mice. Infect Immun. 2006 Oct; 74(10):5730-8. PMID: 16988250.
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    62. Padigel UM, Lee JJ, Nolan TJ, Schad GA, Abraham D. Eosinophils can function as antigen-presenting cells to induce primary and secondary immune responses to Strongyloides stercoralis. Infect Immun. 2006 Jun; 74(6):3232-8. PMID: 16714550.
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    63. Kerepesi LA, Hess JA, Nolan TJ, Schad GA, Abraham D. Complement component C3 is required for protective innate and adaptive immunity to larval strongyloides stercoralis in mice. J Immunol. 2006 Apr 01; 176(7):4315-22. PMID: 16547268.
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    64. Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem. 2006 Apr 21; 281(16):10715-26. PMID: 16484225.
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    65. Kerepesi LA, Leon O, Lustigman S, Abraham D. Protective immunity to the larval stages of onchocerca volvulus is dependent on Toll-like receptor 4. Infect Immun. 2005 Dec; 73(12):8291-7. PMID: 16299326.
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    66. Kerepesi LA, Keiser PB, Nolan TJ, Schad GA, Abraham D, Nutman TB. DNA immunization with Na+-K+ ATPase (Sseat-6) induces protective immunity to larval Strongyloides stercoralis in mice. Infect Immun. 2005 Apr; 73(4):2298-305. PMID: 15784574.
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    67. Denton CP, Abraham DJ. Transgenic analysis of scleroderma: understanding key pathogenic events in vivo. Autoimmun Rev. 2004 Jun; 3(4):285-93. PMID: 15246024.
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    68. Kerepesi LA, Nolan TJ, Schad GA, Lustigman S, Herbert DR, Keiser PB, Nutman TB, Krolewiecki AJ, Abraham D. Human immunoglobulin G mediates protective immunity and identifies protective antigens against larval Strongyloides stercoralis in mice. J Infect Dis. 2004 Apr 01; 189(7):1282-90. PMID: 15031798.
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    69. Abraham D, Leon O, Schnyder-Candrian S, Wang CC, Galioto AM, Kerepesi LA, Lee JJ, Lustigman S. Immunoglobulin E and eosinophil-dependent protective immunity to larval Onchocerca volvulus in mice immunized with irradiated larvae. Infect Immun. 2004 Feb; 72(2):810-7. PMID: 14742524.
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    70. MacDonald AJ, Tawe W, Leon O, Cao L, Liu J, Oksov Y, Abraham D, Lustigman S. Ov-ASP-1, the Onchocerca volvulus homologue of the activation associated secreted protein family is immunostimulatory and can induce protective anti-larval immunity. Parasite Immunol. 2004 Jan; 26(1):53-62. PMID: 15198646.
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    71. Ligas JA, Kerepesi LA, Galioto AM, Lustigman S, Nolan TJ, Schad GA, Abraham D. Specificity and mechanism of immunoglobulin M (IgM)- and IgG-dependent protective immunity to larval Strongyloides stercoralis in mice. Infect Immun. 2003 Dec; 71(12):6835-43. PMID: 14638770.
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    72. Lustigman S, MacDonald AJ, Abraham D. CD4+-dependent immunity to Onchocerca volvulus third-stage larvae in humans and the mouse vaccination model: common ground and distinctions. Int J Parasitol. 2003 Sep 30; 33(11):1161-71. PMID: 13678632.
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    73. Ong VH, Evans LA, Shiwen X, Fisher IB, Rajkumar V, Abraham DJ, Black CM, Denton CP. Monocyte chemoattractant protein 3 as a mediator of fibrosis: Overexpression in systemic sclerosis and the type 1 tight-skin mouse. Arthritis Rheum. 2003 Jul; 48(7):1979-91. PMID: 12847692.
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    74. Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B. Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice. J Biol Chem. 2003 Jul 04; 278(27):25109-19. PMID: 12707256.
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    75. Krolewiecki A, Leon S, Scott P, Abraham D. Activity of azithromycin against Leishmania major in vitro and in vivo. Am J Trop Med Hyg. 2002 Sep; 67(3):273-7. PMID: 12408666.
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    76. Abraham D, Lucius R, Trees AJ. Immunity to Onchocerca spp. in animal hosts. Trends Parasitol. 2002 Apr; 18(4):164-71. PMID: 11998704.
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    77. Lustigman S, James ER, Tawe W, Abraham D. Towards a recombinant antigen vaccine against Onchocerca volvulus. Trends Parasitol. 2002 Mar; 18(3):135-41. PMID: 11854092.
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    78. Nolan TJ, Bhopale VM, Rotman HL, Abraham D, Schad GA. Strongyloides stercoralis: high worm population density leads to autoinfection in the jird (Meriones unguiculatus). Exp Parasitol. 2002 Mar; 100(3):173-8. PMID: 12173402.
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    79. Herbert DR, Nolan TJ, Schad GA, Abraham D. The role of B cells in immunity against larval Strongyloides stercoralis in mice. Parasite Immunol. 2002 Feb; 24(2):95-101. PMID: 11874564.
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    80. Herbert DR, Nolan TJ, Schad GA, Lustigman S, Abraham D. Immunoaffinity-isolated antigens induce protective immunity against larval Strongyloides stercoralis in mice. Exp Parasitol. 2002 Feb; 100(2):112-20. PMID: 12054701.
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    81. McCarthy JS, Wieseman M, Tropea J, Kaslow D, Abraham D, Lustigman S, Tuan R, Guderian RH, Nutman TB. Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans. Infect Immun. 2002 Feb; 70(2):851-8. PMID: 11796620.
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    82. Wang C, Chiarelli LR, Bianchi P, Abraham DJ, Galizzi A, Mattevi A, Zanella A, Valentini G. Human erythrocyte pyruvate kinase: characterization of the recombinant enzyme and a mutant form (R510Q) causing nonspherocytic hemolytic anemia. Blood. 2001 Nov 15; 98(10):3113-20. PMID: 11698298.
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    83. Krolewiecki AJ, Leon S, Scott PA, Nolan TJ, Schad GA, Abraham D. Effect of chronic ethanol consumption on protective T-helper 1 and T-helper 2 immune responses against the parasites Leishmania major and Strongyloides stercoralis in mice. Alcohol Clin Exp Res. 2001 Apr; 25(4):571-8. PMID: 11329498.
      Citations:    
    84. Wang CC, Nolan TJ, Schad GA, Abraham D. Infection of mice with the helminth Strongyloides stercoralis suppresses pulmonary allergic responses to ovalbumin. Clin Exp Allergy. 2001 Mar; 31(3):495-503. PMID: 11260163.
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    85. Abraham D, Leon O, Leon S, Lustigman S. Development of a recombinant antigen vaccine against infection with the filarial worm Onchocerca volvulus. Infect Immun. 2001 Jan; 69(1):262-70. PMID: 11119514.
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    86. Kamishima T, Schweitzer ME, Awaya H, Abraham D. Utilization of "used" vials: cost-effective technique for MR arthrography. J Magn Reson Imaging. 2000 Dec; 12(6):953-5. PMID: 11105035.
      Citations:    
    87. Herbert DR, Lee JJ, Lee NA, Nolan TJ, Schad GA, Abraham D. Role of IL-5 in innate and adaptive immunity to larval Strongyloides stercoralis in mice. J Immunol. 2000 Oct 15; 165(8):4544-51. PMID: 11035095.
      Citations:    
    88. Ko TP, Safo MK, Musayev FN, Di Salvo ML, Wang C, Wu SH, Abraham DJ. Structure of human erythrocyte catalase. Acta Crystallogr D Biol Crystallogr. 2000 Feb; 56(Pt 2):241-5. PMID: 10666617.
      Citations:    
    89. Herkowitz HN, Abraham DJ, Albert TJ. Management of degenerative disc disease above an L5-S1 segment requiring arthrodesis. Spine (Phila Pa 1976). 1999 Jun 15; 24(12):1268-70. PMID: 10382258.
      Citations:    
    90. Johnson EH, Schynder-Candrian S, Rajan TV, Nelson FK, Lustigman S, Abraham D. Immune responses to third stage larvae of Onchocerca volvulus in interferon-gamma and interleukin-4 knockout mice. Parasite Immunol. 1998 Jul; 20(7):319-24. PMID: 9717193.
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    91. Resnicoff M, Valentinis B, Herbert D, Abraham D, Friesen PD, Alnemri ES, Baserga R. The baculovirus anti-apoptotic p35 protein promotes transformation of mouse embryo fibroblasts. J Biol Chem. 1998 Apr 24; 273(17):10376-80. PMID: 9553094.
      Citations:    
    92. Brigandi RA, Rotman HL, Leon O, Nolan TJ, Schad GA, Abraham D. Strongyloides stercoralis host-adapted third-stage larvae are the target of eosinophil-associated immune-mediated killing in mice. J Parasitol. 1998 Apr; 84(2):440-5. PMID: 9576523.
      Citations:    
    93. Resnicoff M, Huang Z, Herbert D, Abraham D, Baserga R. A novel class of peptides that induce apoptosis and abrogate tumorigenesis in vivo. Biochem Biophys Res Commun. 1997 Nov 07; 240(1):208-12. PMID: 9367911.
      Citations:    
    94. Brigandi RA, Rotman HL, Nolan TJ, Schad GA, Abraham D. Chronicity in Strongyloides stercoralis infections: dichotomy of the protective immune response to infective and autoinfective larvae in a mouse model. Am J Trop Med Hyg. 1997 Jun; 56(6):640-6. PMID: 9230796.
      Citations:    
    95. Abraham DJ, Vaccaro AR, Albert TJ, Cotler JM. Gas in the spinal canal associated with injury of the cervical spinal cord: a diagnostic dilemma. A case report. J Bone Joint Surg Am. 1997 Apr; 79(4):591-3. PMID: 9111407.
      Citations:    
    96. Rotman HL, Schnyder-Candrian S, Scott P, Nolan TJ, Schad GA, Abraham D. IL-12 eliminates the Th-2 dependent protective immune response of mice to larval Strongyloides stercoralis. Parasite Immunol. 1997 Jan; 19(1):29-39. PMID: 9121838.
      Citations:    
    97. Resnicoff M, Tjuvajev J, Rotman HL, Abraham D, Curtis M, Aiken R, Baserga R. Regression of C6 rat brain tumors by cells expressing an antisense insulin-like growth factor I receptor RNA. J Exp Ther Oncol. 1996 Nov; 1(6):385-9. PMID: 9414429.
      Citations:    
    98. Rotman HL, Yutanawiboonchai W, Brigandi RA, Leon O, Gleich GJ, Nolan TJ, Schad GA, Abraham D. Strongyloides stercoralis: eosinophil-dependent immune-mediated killing of third stage larvae in BALB/cByJ mice. Exp Parasitol. 1996 Apr; 82(3):267-78. PMID: 8631378.
      Citations:    
    99. Brigandi RA, Rotman HL, Yutanawiboonchai W, Leon O, Nolan TJ, Schad GA, Abraham D. Strongyloides stercoralis: role of antibody and complement in immunity to the third stage of larvae in BALB/cByJ mice. Exp Parasitol. 1996 Apr; 82(3):279-89. PMID: 8631379.
      Citations:    
    100. Yutanawiboonchai W, Brigandi RA, Rotman HL, Abraham D. Structural and molecular specificity of antibody responses in mice immune to third stage larvae of Onchocerca volvulus. Parasite Immunol. 1996 Feb; 18(2):95-102. PMID: 9223162.
      Citations:    
    101. Nolan TJ, Rotman HL, Bhopale VM, Schad GA, Abraham D. Immunity to a challenge infection of Strongyloides stercoralis third-stage larvae in the jird. Parasite Immunol. 1995 Nov; 17(11):599-604. PMID: 8817607.
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    102. Resnicoff M, Burgaud JL, Rotman HL, Abraham D, Baserga R. Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptors. Cancer Res. 1995 Sep 01; 55(17):3739-41. PMID: 7641185.
      Citations:    
    103. Rotman HL, Yutanawiboonchai W, Brigandi RA, Leon O, Nolan TJ, Schad GA, Abraham D. Strongyloides stercoralis: complete life cycle in SCID mice. Exp Parasitol. 1995 Aug; 81(1):136-9. PMID: 7628561.
      Citations:    
    104. Resnicoff M, Abraham D, Yutanawiboonchai W, Rotman HL, Kajstura J, Rubin R, Zoltick P, Baserga R. The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo. Cancer Res. 1995 Jun 01; 55(11):2463-9. PMID: 7758000.
      Citations:    
    105. Abraham D, Rotman HL, Haberstroh HF, Yutanawiboonchai W, Brigandi RA, Leon O, Nolan TJ, Schad GA. Strongyloides stercoralis: protective immunity to third-stage larvae inBALB/cByJ mice. Exp Parasitol. 1995 Mar; 80(2):297-307. PMID: 7895840.
      Citations:    
    106. Abraham D, Bou-Gharios G, Tulip G, Sumner H, Olsen I. Regulation of CD2-mediated heterotypic interactions of murine T lymphocytes. Cell Immunol. 1994 Jul; 156(2):342-56. PMID: 7912994.
      Citations:    
    107. Lange AM, Yutanawiboonchai W, Scott P, Abraham D. IL-4- and IL-5-dependent protective immunity to Onchocerca volvulus infective larvae in BALB/cBYJ mice. J Immunol. 1994 Jul 01; 153(1):205-11. PMID: 8207236.
      Citations:    
    108. Lange AM, Yutanawiboonchai W, Lok JB, Trpis M, Abraham D. Induction of protective immunity against larval Onchocerca volvulus in a mouse model. Am J Trop Med Hyg. 1993 Dec; 49(6):783-8. PMID: 8279644.
      Citations:    
    109. Abraham D, Lange AM, Yutanawiboonchai W, Trpis M, Dickerson JW, Swenson B, Eberhard ML. Survival and development of larval Onchocerca volvulus in diffusion chambers implanted in primate and rodent hosts. J Parasitol. 1993 Aug; 79(4):571-82. PMID: 8331478.
      Citations:    
    110. Abraham D, Eberhard ML, Lange AM, Yutanawiboonchai W, Perler FB, Lok JB. Identification of surrogate rodent hosts for larval Onchocerca lienalis and induction of protective immunity in a model system. J Parasitol. 1992 Jun; 78(3):447-53. PMID: 1597787.
      Citations:    
    111. Lok JB, Abraham D. Animal models for the study of immunity in human filariasis. Parasitol Today. 1992 May; 8(5):168-71. PMID: 15463607.
      Citations:    
    112. Tuan RS, Shepley KJ, Mulligan MM, Abraham D, Perler FB. Histochemical localization of gene expression in Onchocerca volvulus: in situ DNA histohybridization and immunocytochemistry. Mol Biochem Parasitol. 1991 Dec; 49(2):191-203. PMID: 1775163.
      Citations:    
    113. Abraham DJ, Bou-Gharios G, Beauchamp JR, Plater-Zyberk C, Maini RN, Olsen I. Function and regulation of the murine lymphocyte CD2 receptor. J Leukoc Biol. 1991 Apr; 49(4):329-41. PMID: 1672140.
      Citations:    
    114. Abraham D, Grieve RB. Passive transfer of protective immunity to larval Dirofilaria immitis from dogs to BALB/c mice. J Parasitol. 1991 Apr; 77(2):254-7. PMID: 2010857.
      Citations:    
    115. Abraham D, Grieve RB. Genetic control of murine immune responses to larval Dirofilaria immitis. J Parasitol. 1990 Aug; 76(4):523-8. PMID: 2380861.
      Citations:    
    116. Abraham D, Grieve RB, Oaks JA. Dirofilaria immitis: molting process of third-stage larvae. Exp Parasitol. 1990 Apr; 70(3):314-22. PMID: 2311713.
      Citations:    
    117. Arasu P, Nutman TB, Steel C, Mulligan MM, Abraham D, Tuan RS, Perler FB. Human T-cell stimulation, molecular characterization and in situ mRNA localization of a Brugia malayi recombinant antigen. Mol Biochem Parasitol. 1989 Oct; 36(3):223-31. PMID: 2797061.
      Citations:    
    118. Abraham D, Grieve RB, Holy JM, Christensen BM. Immunity to larval Brugia malayi in BALB/c mice: protective immunity and inhibition of larval development. Am J Trop Med Hyg. 1989 Jun; 40(6):598-604. PMID: 2662785.
      Citations:    
    119. Mok M, Grieve RB, Abraham D, Rudin W. Solubilization of epicuticular antigen from Dirofilaria immitis third-stage larvae. Mol Biochem Parasitol. 1988 Nov; 31(2):173-82. PMID: 3054543.
      Citations:    
    120. Grieve RB, Abraham D, Mika-Grieve M, Seibert BP. Induction of protective immunity in dogs to infection with Dirofilaria immitis using chemically-abbreviated infections. Am J Trop Med Hyg. 1988 Oct; 39(4):373-9. PMID: 3189698.
      Citations:    
    121. Bou-Gharios G, Moss J, Abraham D, Partridge T, Olsen I. Ultrastructural studies of a lysosomal enzyme during lymphocyte activation. Br J Exp Pathol. 1988 Oct; 69(5):661-70. PMID: 3264180.
      Citations:    
    122. Abraham D, Grieve RB, Mika-Grieve M. Dirofilaria immitis: surface properties of third- and fourth-stage larvae. Exp Parasitol. 1988 Apr; 65(2):157-67. PMID: 2450771.
      Citations:    
    123. Abraham D, Grieve RB, Mika-Grieve M, Seibert BP. Active and passive immunization of mice against larval Dirofilaria immitis. J Parasitol. 1988 Apr; 74(2):275-82. PMID: 3357118.
      Citations:    
    124. Abraham D, Mok M, Mika-Grieve M, Grieve RB. In vitro culture of Dirofilaria immitis third- and fourth-stage larvae under defined conditions. J Parasitol. 1987 Apr; 73(2):377-83. PMID: 3585632.
      Citations:    
    125. Abraham D, Lauria S, Mika-Grieve M, Lok JB, Grieve RB. Survival and viability of Dirofilaria immitis microfilariae in defined and undefined culture media. J Parasitol. 1986 Oct; 72(5):776-7. PMID: 3806326.
      Citations:    
    126. Abraham D, Weiner DJ, Farrell JP. Cellular and humoral immune responses of jirds resistant to Dipetalonema viteae infection. Infect Immun. 1986 Jun; 52(3):742-7. PMID: 3710584.
      Citations:    
    127. Mok M, Abraham D, Grieve RB, Thomas CB. Thermotaxis in third and fourth-stage Dirofilaria immitis larvae. J Helminthol. 1986 Mar; 60(1):61-4. PMID: 3701022.
      Citations:    
    128. Abraham D, Weiner DJ, Farrell JP. Protective immune responses of the jird to larval Dipetalonema viteae. Immunology. 1986 Jan; 57(1):165-9. PMID: 3943876.
      Citations:    
    129. Weiner DJ, Abraham D, D'Antonio R. Litomosoides carinii in jirds (Meriones unguiculatus): ability to retard development of challenge larvae can be transferred with cells and serum. J Helminthol. 1984 Jun; 58(2):129-37. PMID: 6747255.
      Citations:    
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