Thomas Jefferson University

Howard Krein

TitleProfessor
InstitutionThomas Jefferson University
DepartmentOtolaryngology
Address925 Chestnut Street
Philadelphia PA 19107
Phone215-955-6760
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Garg N, Xu V, Mandloi S, DeKloe J, Kumar A, McCann A, Chandna M, Tekumalla S, Krein H, Heffelfinger R. Ergonomics in Facial Plastic and Reconstructive Surgery: A National Evaluation. Facial Plast Surg Aesthet Med. 2024 Dec 20. PMID: 39699657.
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    2. Garg N, Mandloi S, Queenan N, Trivedi J, McCann A, Xu V, Amin D, Krein H, Heffelfinger R. Patient-Reported Outcome Measures for Mohs Reconstruction: A Systematic Review. OTO Open. 2024 Oct-Dec; 8(4):e70054. PMID: 39697816.
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    3. Garg N, Xu V, Mandloi S, Kumar A, Chandna M, Tekumalla S, McCann A, Krein H, Heffelfinger R. Ergonomics in Facial Plastic and Reconstructive Surgery: A Clinical Evaluation. Laryngoscope. 2024 Oct 19. PMID: 39425600.
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    4. Garg N, Campbell DJ, Yang A, McCann A, Moroco AE, Estephan LE, Palmer WJ, Krein H, Heffelfinger R. Chatbots as Patient Education Resources for Aesthetic Facial Plastic Surgery: Evaluation of ChatGPT and Google Bard Responses. Facial Plast Surg Aesthet Med. 2024 Jul 01. PMID: 38946595.
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    5. Chandna M, Kumar A, Crippen M, Sakkal M, Guler M, Garg N, Tekumalla S, Barbarite E, Krein H, Heffelfinger R. Factors Predicting Discharge Disposition Following Head and Neck Free Flap Reconstruction. Laryngoscope. 2023 Dec 14. PMID: 38098138.
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    6. Wagoner SF, Sagalow ES, Chandna M, Kumar AT, Gill K, Amin D, Banoub R, Barbarite E, Alapati R, Stanek J, Baer S, Krein H, Heffelfinger R. The Impact of Surgical and Nonsurgical Interventions on Overall Oral, Palpebral Fissure, and Brow Height Symmetry in a Patient with Facial Synkinesis. Facial Plast Surg Aesthet Med. 2023 Dec 11. PMID: 38079235.
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    7. Agarwal A, Philips R, Fiorella M, Amin DR, Krein H, Heffelfinger R. Complications and Functional Outcomes After Esophageal Reconstruction with an Intact Larynx. Laryngoscope. 2023 Sep 15. PMID: 37712564.
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    8. Philips R, Best KA, Agarwal A, Sagheer H, Selman Y, Sweeney L, Wax M, Krein H, Heffelfinger R, Luginbuhl A, Curry J. A Survey of Microvascular Technique Preferences Among American Head Neck Society Members. Laryngoscope. 2023 Aug 23. PMID: 37610286.
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    9. Schlegel L, Malani E, Belko S, Kumar A, Barbarite E, Krein H, Hefelfnger R, Hutchinson M, Pugliese R. Correction to: Design, printing optimization, and material testing of a 3D-printed nasal osteotomy task trainer. 3D Print Med. 2023 Aug 21; 9(1):23. PMID: 37603078.
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    10. Schlegel L, Malani E, Belko S, Kumar A, Barbarite E, Krein H, Heffelfinger R, Hutchinson M, Pugliese R. Design, printing optimization, and material testing of a 3D-printed nasal osteotomy task trainer. 3D Print Med. 2023 Jul 13; 9(1):20. PMID: 37439899.
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    11. Sagalow ES, Estephan LE, Kumar AT, Hwang M, Krein H, Heffelfinger R. Recovery Benefit With Total Intravenous Anesthesia in Patients Receiving Rhinoplasty. Otolaryngol Head Neck Surg. 2023 Mar 11. PMID: 36906818.
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    12. Elliot ZT, Lu JS, Campbell D, Xiao KB, Christopher V, Krein H, Heffelfinger R. Evaluating YouTube Videos on Facelift Surgery for Facial Rejuvenation as a Resource for Patients. Ann Otol Rhinol Laryngol. 2023 Feb 14; 34894231154410. PMID: 36788443.
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    13. Schlegel L, Kumar A, Christopher V, Belko S, Barbarite E, Pugliese R, Krein H, Hutchinson M, Heffelfinger R. Tap-Tap: Learning Endonasal and Percutaneous Nasal Osteotomy Techniques on 3D-Printed Midface Models. Otolaryngol Head Neck Surg. 2023 Jan 30. PMID: 36939489.
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    14. Agarwal A, Philips R, Landers K, Savitch S, Barbarite E, Krein H, Heffelfinger R. Functional and Symmetry Outcomes After Forehead Flap Reconstruction of Medial Peri-Ocular Defects. Laryngoscope. 2023 Jan 16. PMID: 36644993.
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    15. Elliott ZT, Bheemreddy A, Fiorella M, Martin AM, Christopher V, Krein H, Heffelfinger R. Artificial intelligence for objectively measuring years regained after facial rejuvenation surgery. Am J Otolaryngol. 2022 Dec 26; 44(2):103775. PMID: 36706713.
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    16. Sagalow ES, Stewart M, Estephan L, Rodin J, Ananth A, Curcio B, Krein H, Heffelfinger R, Thaler A, Hunt P, Boon M, Huntley C. Assessing Postoperative Recovery With Volatile Gas Versus Total Intravenous Anesthesia in Patients With and Without Obstructive Sleep Apnea. Ann Otol Rhinol Laryngol. 2022 Jul 14; 34894221112501. PMID: 35833578.
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    17. Sagalow ES, Christopher V, Banoub RG, Gill KS, Xu V, Jain N, Malkani K, Elmer N, Zhan T, Stanek JJ, Hwang M, Krein HD, Heffelfinger RN. Rate of Fat Graft Volume Loss After Parotidectomy. J Craniofac Surg. 2022 Mar 08. PMID: 35258011.
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    18. Sagalow ES, Givens AK, Gill K, Malkani K, Xu V, Elmer N, Ganti R, Zhan T, Stanek J, Hwang MS, Krein H, Heffelfinger R. Impact of great auricular nerve sacrifice on sensory disturbance after parotidectomy. Am J Otolaryngol. 2022 Feb 02; 43(2):103387. PMID: 35149344.
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    19. Sussman S, Gill K, Wagoner S, Stanek J, Heffelfinger R, Krein H. A randomized control trial employing infraorbital nerve stimulation as a neural distractor during nasopharyngeal swab. Ear Nose Throat J. 2022 Jan 28; 1455613211069344. PMID: 35089070.
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    20. Sagheer SH, Yan BM, Bovenzi CD, Nwagu U, Cognetti D, Krein H, Heffelfinger R. Postoperative Opioid-Prescribing Practices in Nasal Surgery: A Prospective Study. Facial Plast Surg Aesthet Med. 2021 Jun 25. PMID: 34171976.
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    21. Xu V, Gill KS, Goldfarb J, Bovenzi C, Moayer R, Krein H, Heffelfinger R. First Bite Syndrome After Parotidectomy: A Case Series and Review of Literature. Ear Nose Throat J. 2020 Dec 14; 145561320980179. PMID: 33314982.
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    22. Ho M, Goldfarb J, Moayer R, Nwagu U, Ganti R, Krein H, Heffelfinger R, Hutchinson ML. Design and Printing of a Low-Cost 3D-Printed Nasal Osteotomy Training Model: Development and Feasibility Study. JMIR Med Educ. 2020 Nov 17; 6(2):e19792. PMID: 33200998.
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    23. Sweeny L, Curry J, Crawley M, Cave T, Stewart M, Luginbuhl A, Heffelfinger R, Krein H, Petrisor D, Bender-Heine A, Wax MK. Factors impacting successful salvage of the failing free flap. Head Neck. 2020 Aug 26. PMID: 32844522.
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    24. Hjelm N, Goldfarb J, Krein H, Heffelfinger RN, Pribitkin E. Sonic Rhinoplasty: Review and Updated Uses. Facial Plast Surg. 2020 Aug 24. PMID: 32838439.
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    25. Bovenzi CD, Manges KA, Krein H, Heffelfinger R. Online Ratings of Facial Plastic Surgeons: Worthwhile Additions to Conventional Patient Experience Surveys. Facial Plast Surg Aesthet Med. 2020 Jul 22. PMID: 32716653.
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    26. Swendseid B, Philips R, Rimmer R, Goldman RA, Luginbuhl AJ, Curry J, Krein H, Heffelfinger R. Postoperative Anatomic Position of Mandibular Free Flap Neocondyles Affects Patient Symptoms. Facial Plast Surg Aesthet Med. 2020 Jul 02. PMID: 32614617.
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    27. Swendseid B, Kumar A, Sweeny L, Zhan T, Goldman RA, Krein H, Heffelfinger RN, Luginbuhl AJ, Curry JM. Natural History and Consequences of Nonunion in Mandibular and Maxillary Free Flaps. Otolaryngol Head Neck Surg. 2020 Jun 16; 194599820931069. PMID: 32539525.
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    28. Swendseid B, Kumar A, Sweeny L, Wax MK, Zhan T, Goldman RA, Krein H, Heffelfinger RN, Luginbuhl AJ, Curry JM. Long-Term Complications of Osteocutaneous Free Flaps in Head and Neck Reconstruction. Otolaryngol Head Neck Surg. 2020 Mar 24; 194599820912727. PMID: 32204662.
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    29. Bovenzi CD, Ciolek P, Crippen M, Curry JM, Krein H, Heffelfinger R. Reconstructive trends and complications following parotidectomy: incidence and predictors in 11,057 cases. J Otolaryngol Head Neck Surg. 2019 Nov 19; 48(1):64. PMID: 31744535.
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    30. Philips R, Topf MC, Graf A, Krein H, Heffelfinger R, Luginbuhl A, Curry J. Orbital outcomes after orbit-sparing surgery and free flap reconstruction. Oral Oncol. 2019 Sep 25; 98:78-84. PMID: 31563040.
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    31. Hjelm N, Sanan A, Krein H, Heffelfinger RN. Safety of Concurrent Endoscopic Browlift and Blepharoplasty. Facial Plast Surg. 2019 Sep 10. PMID: 31505687.
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    32. Crawley MB, Sweeny L, Ravipati P, Heffelfinger R, Krein H, Luginbuhl A, Goldman R, Curry J. Factors Associated with Free Flap Failures in Head and Neck Reconstruction. Otolaryngol Head Neck Surg. 2019 Aug 06; 194599819860809. PMID: 31382816.
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    33. Sweeny L, Topf M, Wax MK, Rosenthal EL, Greene BJ, Heffelfinger R, Krein H, Luginbuhl A, Petrisor D, Troob SH, Hughley B, Hong S, Zhan T, Curry J. Shift in the timing of microvascular free tissue transfer failures in head and neck reconstruction. Laryngoscope. 2019 Jul 09. PMID: 31287566.
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    34. Hjelm N, Ortlip TE, Topf M, Luginbuhl A, Curry J, Krein H, Heffelfinger R. Functional outcomes of temporomandibular joint reconstruction with vascularized tissue. Am J Otolaryngol. 2019 Sep - Oct; 40(5):691-695. PMID: 31227259.
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    35. Sanan A, Hjelm N, Tassone P, Krein H, Heffelfinger RN. Thermistor-controlled subdermal skin tightening for the aging face: Clinical outcomes and efficacy. Laryngoscope Investig Otolaryngol. 2019 Feb; 4(1):18-23. PMID: 30828614.
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    36. Tassone P, Gill KS, Hsu D, Nyquist G, Krein H, Bilyk JR, Murchison AP, Evans JJ, Heffelfinger RN, Curry JM. Naso- or Orbitocutaneous Fistulas after Free Flap Reconstruction of Orbital Exenteration Defects: Retrospective Study, Systematic Review, and Meta-Analysis. J Neurol Surg B Skull Base. 2017 Aug; 78(4):337-345. PMID: 28725521.
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    37. Mitchell CA, Goldman RA, Curry JM, Cognetti DM, Krein H, Heffelfinger R, Luginbuhl A. Morbidity and Survival in Elderly Patients Undergoing Free Flap Reconstruction: A Retrospective Cohort Study. Otolaryngol Head Neck Surg. 2017 Jul; 157(1):42-47. PMID: 28319459.
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    38. Gill KS, Hsu D, Tassone P, Pluta J, Nyquist G, Krein H, Bilyk J, Murchison AP, Iloreta A, Evans JJ, Heffelfinger RN, Curry JM. Postoperative cerebrospinal fluid leak after microvascular reconstruction of craniofacial defects with orbital exenteration. Laryngoscope. 2017 Apr; 127(4):835-841. PMID: 27601262.
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    39. Balceniuk MD, Wingate NA, Krein H, Curry J, Cognetti D, Heffelfiner R, Luginbuhl A. Effects of a Fibrin Sealant on Skin Graft Tissue Adhesion in a Rodent Model. Otolaryngol Head Neck Surg. 2016 Jul; 155(1):76-80. PMID: 26932970.
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    40. Bryant LM, Cognetti D, Baker A, Roy S, Johnston DR, Curry J, Krein H. Esthetic and functional reconstruction after parotidectomy in pediatric patients - A case series. Int J Pediatr Otorhinolaryngol. 2015 Dec; 79(12):2442-5. PMID: 26474834.
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    41. Roy S, Iloreta AM, Bryant LM, Krein HD, Pribitkin EA, Heffelfinger RN. Piriform aperture enlargement for nasal obstruction. Laryngoscope. 2015 Nov; 125(11):2468-71. PMID: 25946485.
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    42. Gordin EA, Luginbuhl AL, Ortlip T, Heffelfinger RN, Krein H. Subcutaneous vs Intramuscular Botulinum Toxin: Split-Face Randomized Study. JAMA Facial Plast Surg. 2014 May 1; 16(3):193-8. PMID: 24699554.
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    43. Parkes WJ, Greywoode J, O'Hara BJ, Heffelfinger RN, Krein H. A preliminary report of percutaneous craniofacial osteoplasty in a rat calvarium. Laryngoscope. 2014 Jul; 124(7):1550-3. PMID: 24122773.
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    44. Heffelfinger R, Murchison AP, Parkes W, Krein H, Curry J, Evans JJ, Bilyk JR. Microvascular free flap reconstruction of orbitocraniofacial defects. Orbit. 2013 Apr; 32(2):95-101. PMID: 23514024.
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    45. Parkes WJ, Krein H, Heffelfinger R, Curry J. Use of the anterolateral thigh in cranio-orbitofacial reconstruction. Plast Surg Int. 2011; 2011:941742. PMID: 22567249.
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    46. Lavasani L, Leventhal D, Constantinides M, Krein H. Management of acute soft tissue injury to the auricle. Facial Plast Surg. 2010 Dec; 26(6):445-50. PMID: 21086230.
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    47. Greywoode JD, Pribitkin EA, Krein H. Management of auricular hematoma and the cauliflower ear. Facial Plast Surg. 2010 Dec; 26(6):451-5. PMID: 21086231.
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    48. Gordin EA, Daniero JJ, Krein H, Boon MS. Parotid gland trauma. Facial Plast Surg. 2010 Dec; 26(6):504-10. PMID: 21086237.
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    49. Ezzat WH, Dahl JP, Luginbuhl A, Gordin E, Krein H, Heffelfinger RN. Recombinant human tissue factor pathway inhibitor prevents thrombosis in a venous tuck model. Laryngoscope. 2010 Nov; 120(11):2172-6. PMID: 20939073.
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    50. Luginbuhl AJ, Pribitkin EA, Krein H, Heffelfinger RN. Assessment of microvascular anastomosis training in otolaryngology residencies: survey of United States program directors. Otolaryngol Head Neck Surg. 2010 Nov; 143(5):633-6. PMID: 20974331.
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    51. Murray RC, Gordin EA, Saigal K, Leventhal D, Krein H, Heffelfinger RN. Reconstruction of the radial forearm free flap donor site using integra artificial dermis. Microsurgery. 2011 Feb; 31(2):104-8. PMID: 20939003.
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    52. Luginbuhl A, Pribitkin E, Krein H, Heffelfinger R. Assessment of microvascular anastomosis training in otolaryngology residencies: survey of United States program directors. Laryngoscope. 2010; 120 Suppl 4:S233. PMID: 21225831.
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    53. Grunebaum LD, Rosen D, Krein HD, Keane WM, Curtis M, Tereschuk DA, Pribitkin EA. Nerve monitoring and stimulation during endoscopic neck surgery in the pig. Laryngoscope. 2005 Apr; 115(4):712-6. PMID: 15805886.
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    54. Krein HD, Greenbaum SS, Reiter D. Color-specific enhancement of digital photographs for identification of the extent of cutaneous malignancy. Arch Facial Plast Surg. 2005 Mar-Apr; 7(2):135-7. PMID: 15781726.
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