Harumitsu Hirata

TitleAssoc Prof CHP
InstitutionThomas Jefferson University
DepartmentNursing - Undergraduate
Address900 Walnut Street
Philadelphia PA 19107
Phone401-248-3983
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ivakhnitskaia E, Souboch V, Dallacasagrande V, Mizerska K, Souboch E, Sarkar J, Guaiquil VH, Tseng KY, Hirata H, Rosenblatt MI. Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity. Ocul Surf. 2022 10; 26:88-96. PMID: 35934279.
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    2. Hirata H, Dallacasagrande V, Mizerska K, Ivakhnitskaia E, Rosenblatt MI. Ambient Air Currents Activate Corneal Nerves During Ocular Desiccation in Rats: Simultaneous Recordings of Neural Activity and Corneal Temperature. Invest Ophthalmol Vis Sci. 2018 Aug 01; 59(10):4031-4043. PMID: 30098191.
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    3. Hirata H, Mizerska K, Dallacasagrande V, Guaiquil VH, Rosenblatt MI. Acute corneal epithelial debridement unmasks the corneal stromal nerve responses to ocular stimulation in rats: implications for abnormal sensations of the eye. J Neurophysiol. 2017 May 01; 117(5):1935-1947. PMID: 28250152.
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    4. Hirata H, Mizerska K, Dallacasagrande V, Rosenblatt MI. Estimating the Osmolarities of Tears During Evaporation Through the "Eyes" of the Corneal Nerves. Invest Ophthalmol Vis Sci. 2017 Jan 01; 58(1):168-178. PMID: 28114576.
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    5. Hirata H, Mizerska K, Marfurt CF, Rosenblatt MI. Hyperosmolar Tears Induce Functional and Structural Alterations of Corneal Nerves: Electrophysiological and Anatomical Evidence Toward Neurotoxicity. Invest Ophthalmol Vis Sci. 2015 Dec 1; 56(13):8125-40. PMID: 26720465.
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    6. Hirata H, Rosenblatt MI. Hyperosmolar tears enhance cooling sensitivity of the corneal nerves in rats: possible neural basis for cold-induced dry eye pain. Invest Ophthalmol Vis Sci. 2014; 55(9):5821-33. PMID: 25139732.
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    7. Hirata H, Fried N, Oshinsky ML. Quantitative characterization reveals three types of dry-sensitive corneal afferents: pattern of discharge, receptive field, and thermal and chemical sensitivity. J Neurophysiol. 2012 Nov; 108(9):2481-93. PMID: 22914652.
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    8. Hirata H, Oshinsky ML. Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels. J Neurophysiol. 2012 Feb; 107(4):1199-209. PMID: 22114162.
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    9. Hirata H, Meng ID. Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: implications for dry eye disease. Invest Ophthalmol Vis Sci. 2010 Aug; 51(8):3969-76. PMID: 20335617.
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    10. Bereiter DA, Okamoto K, Tashiro A, Hirata H. Endotoxin-induced uveitis causes long-term changes in trigeminal subnucleus caudalis neurons. J Neurophysiol. 2005 Dec; 94(6):3815-25. PMID: 16049140.
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    11. Hirata H, Okamoto K, Tashiro A, Bereiter DA. A novel class of neurons at the trigeminal subnucleus interpolaris/caudalis transition region monitors ocular surface fluid status and modulates tear production. J Neurosci. 2004 Apr 28; 24(17):4224-32. PMID: 15115818.
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    12. Hirata H, Okamoto K, Bereiter DA. GABA(A) receptor activation modulates corneal unit activity in rostral and caudal portions of trigeminal subnucleus caudalis. J Neurophysiol. 2003 Nov; 90(5):2837-49. PMID: 12890797.
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