Irwin Levitan

TitleProfessor & Chair JMC
InstitutionThomas Jefferson University
DepartmentChair SKMC
Address900 Walnut Street
Philadelphia PA 19107
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    R01NS017910     (LEVITAN, IRWIN B)Jul 1, 1982 - Aug 31, 2011
    NIH
    Regulation of ion channels in nerve cells
    Role: Principal Investigator

    R13NS023383     (LEVITAN, IRWIN B)Apr 1, 1986 - Mar 31, 1987
    NIH
    ION CHANNELS IN MUSCLE &OTHER EXCITABLE MEMBRANES
    Role: Principal Investigator

    R01NS025366     (LEVITAN, IRWIN B)Feb 1, 1988 - Jan 31, 1993
    NIH
    REGULATION OF SYNAPTIC SPECIFICITY
    Role: Principal Investigator

    T32MH019929     (GRIFFITH, LESLIE C)Sep 30, 1994 - Jun 30, 2024
    NIH
    Neuroscience: From Channels to Behavior
    Role: Co-Principal Investigator

    R01GM053942     (LEVITAN, IRWIN B)May 1, 1997 - Apr 30, 2002
    NIH
    MODULATION OF VOLTAGE DEPENDENT POTASSIUM CHANNELS
    Role: Principal Investigator

    R01AG032279     (LEVITAN, IRWIN B)Apr 1, 2009 - Mar 31, 2015
    NIH
    Mechanisms underlying Abeta42-induced neuronal dysfunction and degeneration
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Barber KR, Hruska M, Bush KM, Martinez JA, Fei H, Levitan IB, Dalva MB, Wairkar YP. Levels of Par-1 kinase determine the localization of Bruchpilot at the Drosophila neuromuscular junction synapses. Sci Rep. 2018 Oct 31; 8(1):16099. PMID: 30382129.
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    2. Levitan IB. Sugar and spice and potassium channel modulation. Channels (Austin). 2017 Jan 24; 1-2. PMID: 28118079.
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    3. Jepson JE, Shahidullah M, Liu D, le Marchand SJ, Liu S, Wu MN, Levitan IB, Dalva MB, Koh K. Regulation of synaptic development and function by the Drosophila PDZ protein Dyschronic. Development. 2014 Dec; 141(23):4548-57. PMID: 25359729.
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    4. Shahidullah M, Le Marchand SJ, Fei H, Zhang J, Pandey UB, Dalva MB, Pasinelli P, Levitan IB. Defects in Synapse Structure and Function Precede Motor Neuron Degeneration in Drosophila Models of FUS-Related ALS. J Neurosci. 2013 Dec 11; 33(50):19590-8. PMID: 24336723.
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    5. Jepson J, Sheldon A, Shahidullah M, Fei H, Koh K, Levitan IB. Cell-specific fine-tuning of neuronal excitability by differential expression of modulator protein isoforms. J Neurosci. 2013 Oct 16; 33(42):16767-77. PMID: 24133277.
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    6. Sheldon AL, Zhang J, Fei H, Levitan IB. SLOB, a SLOWPOKE channel binding protein, regulates insulin pathway signaling and metabolism in Drosophila. PLoS One. 2011; 6(8):e23343. PMID: 21850269.
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    7. Ma H, Zhang J, Levitan IB. Slob, a Slowpoke channel-binding protein, modulates synaptic transmission. J Gen Physiol. 2011 Feb; 137(2):225-38. PMID: 21282401.
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    8. Crocker A, Shahidullah M, Levitan IB, Sehgal A. Identification of a neural circuit that underlies the effects of octopamine on sleep:wake behavior. Neuron. 2010 Mar 11; 65(5):670-81. PMID: 20223202.
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    9. Shahidullah M, Reddy S, Fei H, Levitan IB. In vivo role of a potassium channel-binding protein in regulating neuronal excitability and behavior. J Neurosci. 2009 Oct 21; 29(42):13328-37. PMID: 19846720.
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    10. Levitan IB. miXED messages in ion channel modulation. Neuron. 2008 Jul 31; 59(2):188-9. PMID: 18667146.
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    11. Gao L, Fei H, Connors NC, Zhang J, Levitan IB. Drosophila ortholog of succinyl-CoA synthetase {beta} subunit: a novel modulator of Drosophila KCNQ channels. J Neurophysiol. 2008 May; 99(5):2736-40. PMID: 18385479.
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    12. Zeng H, Weiger TM, Fei H, Levitan IB. Mechanisms of two modulatory actions of the channel-binding protein Slob on the Drosophila Slowpoke calcium-dependent potassium channel. J Gen Physiol. 2006 Nov; 128(5):583-91. PMID: 17074977.
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    13. Levitan IB. Signaling protein complexes associated with neuronal ion channels. Nat Neurosci. 2006 Mar; 9(3):305-10. PMID: 16498425.
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    14. Jaramillo AM, Zeng H, Fei H, Zhou Y, Levitan IB. Expression and function of variants of slob, slowpoke channel binding protein, in Drosophila. J Neurophysiol. 2006 Mar; 95(3):1957-65. PMID: 16339006.
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    15. Wen H, Weiger TM, Ferguson TS, Shahidullah M, Scott SS, Levitan IB. A Drosophila KCNQ channel essential for early embryonic development. J Neurosci. 2005 Nov 2; 25(44):10147-56. PMID: 16267222.
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    16. Shahidullah M, Santarelli LC, Wen H, Levitan IB. Expression of a calmodulin-binding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability. Proc Natl Acad Sci U S A. 2005 Nov 8; 102(45):16454-9. PMID: 16263935.
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    17. Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB. MONaKA, a novel modulator of the plasma membrane Na,K-ATPase. J Neurosci. 2005 Aug 31; 25(35):7934-43. PMID: 16135750.
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    18. Zeng H, Weiger TM, Fei H, Jaramillo AM, Levitan IB. The amino terminus of Slob, Slowpoke channel binding protein, critically influences its modulation of the channel. J Gen Physiol. 2005 Jun; 125(6):631-40. PMID: 15897294.
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    19. Cibulsky SM, Fei H, Levitan IB. Syntaxin-1A binds to and modulates the Slo calcium-activated potassium channel via an interaction that excludes syntaxin binding to calcium channels. J Neurophysiol. 2005 Mar; 93(3):1393-405. PMID: 15496493.
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    20. Zeng H, Fei H, Levitan IB. The slowpoke channel binding protein Slob from Drosophila melanogaster exhibits regulatable protein kinase activity. Neurosci Lett. 2004 Jul 15; 365(1):33-8. PMID: 15234468.
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    21. Levitan IB. Cell biology. A well-stocked pool. Science. 2004 Apr 16; 304(5669):394-5. PMID: 15087533.
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    22. Jaramillo AM, Zheng X, Zhou Y, Amado DA, Sheldon A, Sehgal A, Levitan IB. Pattern of distribution and cycling of SLOB, Slowpoke channel binding protein, in Drosophila. BMC Neurosci. 2004 Jan 27; 5:3. PMID: 15005796.
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    23. Zhou Y, Fei H, Levitan IB. An interaction domain in Slob necessary for its binding to the slowpoke calcium-dependent potassium channel. Neuropharmacology. 2003 Nov; 45(6):714-9. PMID: 14529710.
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    24. Zhou Y, Reddy S, Murrey H, Fei H, Levitan IB. Monomeric 14-3-3 protein is sufficient to modulate the activity of the Drosophila slowpoke calcium-dependent potassium channel. J Biol Chem. 2003 Mar 21; 278(12):10073-80. PMID: 12529354.
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    25. Wen H, Levitan IB. Calmodulin is an auxiliary subunit of KCNQ2/3 potassium channels. J Neurosci. 2002 Sep 15; 22(18):7991-8001. PMID: 12223552.
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    26. Jin P, Weiger TM, Levitan IB. Reciprocal modulation between the alpha and beta 4 subunits of hSlo calcium-dependent potassium channels. J Biol Chem. 2002 Nov 15; 277(46):43724-9. PMID: 12223479.
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    27. Zhou Y, Wang J, Wen H, Kucherovsky O, Levitan IB. Modulation of Drosophila slowpoke calcium-dependent potassium channel activity by bound protein kinase a catalytic subunit. J Neurosci. 2002 May 15; 22(10):3855-63. PMID: 12019304.
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    28. Weiger TM, Hermann A, Levitan IB. Modulation of calcium-activated potassium channels. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2002 Mar; 188(2):79-87. PMID: 11919690.
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    29. Jin P, Weiger TM, Wu Y, Levitan IB. Phosphorylation-dependent functional coupling of hSlo calcium-dependent potassium channel and its hbeta 4 subunit. J Biol Chem. 2002 Mar 22; 277(12):10014-20. PMID: 11790768.
      Citations:    
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