Thomas Jefferson University

Jing Chen-Roetling

TitleAssoc Prof CHP
InstitutionThomas Jefferson University
DepartmentNursing - Undergraduate
Address1020 Sansom St.
Philadelphia PA 19107
Phone215-955-6844
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yamazaki S, Valekunja UK, Chen-Roetling J, Reddy AB. Heat Shock Factor 1 Governs Sleep-Wake Cycles Across Species. bioRxiv. 2024 Nov 17. PMID: 39605613.
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    2. Chen-Roetling J, Li Y, Cao Y, Yan Z, Lu X, Regan RF. Effect of hemopexin treatment on outcome after intracerebral hemorrhage in mice. Brain Res. 2021 Apr 28; 1765:147507. PMID: 33930375.
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    3. Chen-Roetling J, Cao Y, Peng D, Regan RF. Rapid Loss of Perihematomal Cell Viability in the Collagenase Intracerebral Hemorrhage Model. Brain Res. 2019 Jan 10. PMID: 30639124.
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    4. Chen-Roetling J, Regan KA, Regan RF. Protective effect of vitreous against hemoglobin neurotoxicity. Biochem Biophys Res Commun. 2018 Jun 06. PMID: 29859185.
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    5. Chen-Roetling J, Ma SK, Cao Y, Shah A, Regan RF. Hemopexin Increases the Neurotoxicity of Hemoglobin When Haptoglobin is Absent. J Neurochem. 2018 Mar 03. PMID: 29500821.
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    6. Chen-Roetling J, Kamalapathy P, Cao Y, Song W, Schipper HM, Regan RF. Astrocyte heme oxygenase-1 reduces mortality and improves outcome after collagenase-induced intracerebral hemorrhage. Neurobiol Dis. 2017 Jun; 102:140-146. PMID: 28323022.
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    7. Chen-Roetling J, Regan RF. Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage. Curr Pharm Des. 2016 Oct 27. PMID: 27799046.
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    8. Chen-Roetling J, Regan RF. Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin. J Neurochem. 2016 Nov; 139(4):586-595. PMID: 27364920.
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    9. Chen-Roetling J, Song W, Schipper HM, Regan CS, Regan RF. Astrocyte overexpression of heme oxygenase-1 improves outcome after intracerebral hemorrhage. Stroke. 2015 Apr; 46(4):1093-8. PMID: 25690543.
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    10. Chen-Roetling J, Lu X, Regan RF. Targeting heme oxygenase after intracerebral hemorrhage. Ther Targets Neurol Dis. 2015 Jan 03; 2(1). PMID: 25642455.
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    11. Chen-Roetling J, Cai Y, Regan RF. Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage. BMC Res Notes. 2014; 7(1):561. PMID: 25149897.
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    12. Lu X, Chen-Roetling J, Regan RF. Systemic hemin therapy attenuates blood-brain barrier disruption after intracerebral hemorrhage. Neurobiol Dis. 2014 Oct; 70:245-51. PMID: 24952361.
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    13. Chen-Roetling J, Cai Y, Lu X, Regan RF. Hemin uptake and release by neurons and glia. Free Radic Res. 2014 Feb; 48(2):200-5. PMID: 24164169.
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    14. Chen-Roetling J, Lu X, Regan KA, Regan RF. A rapid fluorescent method to quantify neuronal loss after experimental intracerebral hemorrhage. J Neurosci Methods. 2013 Jun 15; 216(2):128-36. PMID: 23583700.
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    15. Chen-Roetling J, Sinanan J, Regan RF. Effect of iron chelators on methemoglobin and thrombin preconditioning. Transl Stroke Res. 2012 Dec; 3(4):452-9. PMID: 23585819.
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    16. Chen-Roetling J, Liu W, Regan RF. Hemopexin decreases hemin accumulation and catabolism by neural cells. Neurochem Int. 2012 Apr; 60(5):488-94. PMID: 22342655.
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    17. Chen-Roetling J, Liu W, Regan RF. Iron accumulation and neurotoxicity in cortical cultures treated with holotransferrin. Free Radic Biol Med. 2011 Dec 1; 51(11):1966-74. PMID: 21939754.
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    18. Chen L, Zhang X, Chen-Roetling J, Regan RF. Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice. J Neurosurg. 2011 Apr; 114(4):1159-67. PMID: 21128737.
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    19. Chen-Roetling J, Chen L, Regan RF. Apotransferrin protects cortical neurons from hemoglobin toxicity. Neuropharmacology. 2011 Feb-Mar; 60(2-3):423-31. PMID: 21034753.
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    20. Jaremko KM, Chen-Roetling J, Chen L, Regan RF. Accelerated hemolysis and neurotoxicity in neuron-glia-blood clot co-cultures. J Neurochem. 2010 Aug; 114(4):1063-73. PMID: 20497302.
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    21. Chen M, Awe OO, Chen-Roetling J, Regan RF. Iron regulatory protein-2 knockout increases perihematomal ferritin expression and cell viability after intracerebral hemorrhage. Brain Res. 2010 Jun 14; 1337:95-103. PMID: 20399759.
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    22. Chen-Roetling J, Chen L, Regan RF. Minocycline attenuates iron neurotoxicity in cortical cell cultures. Biochem Biophys Res Commun. 2009 Aug 21; 386(2):322-6. PMID: 19523448.
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    23. Li Z, Chen-Roetling J, Regan RF. Increasing expression of H- or L-ferritin protects cortical astrocytes from hemin toxicity. Free Radic Res. 2009 Jun; 43(6):613-21. PMID: 19513908.
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    24. Chen-Roetling J, Li Z, Chen M, Awe OO, Regan RF. Heme oxygenase activity and hemoglobin neurotoxicity are attenuated by inhibitors of the MEK/ERK pathway. Neuropharmacology. 2009 Apr; 56(5):922-8. PMID: 19371583.
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    25. Chen-Roetling J, Li Z, Regan RF. Hemoglobin neurotoxicity is attenuated by inhibitors of the protein kinase CK2 independent of heme oxygenase activity. Curr Neurovasc Res. 2008 Aug; 5(3):193-8. PMID: 18691077.
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    26. Regan RF, Li Z, Chen M, Zhang X, Chen-Roetling J. Iron regulatory proteins increase neuronal vulnerability to hydrogen peroxide. Biochem Biophys Res Commun. 2008 Oct 10; 375(1):6-10. PMID: 18655771.
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    27. Regan RF, Chen M, Li Z, Zhang X, Benvenisti-Zarom L, Chen-Roetling J. Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobin. Neurobiol Dis. 2008 Aug; 31(2):242-9. PMID: 18571425.
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    28. Qu Y, Chen-Roetling J, Benvenisti-Zarom L, Regan RF. Attenuation of oxidative injury after induction of experimental intracerebral hemorrhage in heme oxygenase-2 knockout mice. J Neurosurg. 2007 Mar; 106(3):428-35. PMID: 17367065.
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    29. Chen-Roetling J, Regan RF. Effect of heme oxygenase-1 on the vulnerability of astrocytes and neurons to hemoglobin. Biochem Biophys Res Commun. 2006 Nov 10; 350(1):233-7. PMID: 16999934.
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    30. Benvenisti-Zarom L, Chen-Roetling J, Regan RF. Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury. Neurosci Lett. 2006 May 8; 398(3):230-4. PMID: 16443326.
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    31. Chen-Roetling J, Benvenisti-Zarom L, Regan RF. Cultured astrocytes from heme oxygenase-1 knockout mice are more vulnerable to heme-mediated oxidative injury. J Neurosci Res. 2005 Dec 15; 82(6):802-10. PMID: 16273550.
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