Thomas Jefferson University

Karl Doghramji

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentPsychiatry
Address1025 Walnut St.
Philadelphia PA 19107
Phone215-955-8285
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    Board Certified Sleep Specialist
    Program Director, fellowship in sleep medicine


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Owens S, Doghramji K. Effect of telemonitoring and as-needed patient support on positive airway pressure therapy adherence. J Am Assoc Nurse Pract. 2024 Feb 29. PMID: 38421277.
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    2. Tekumalla S, Plawecki A, Kaffenberger T, Alapati R, Doghramji K, Boon M, Huntley C. The relationship between positive airway pressure tolerance and adherence: defining a new metric. J Clin Sleep Med. 2024 Feb 02. PMID: 38305783.
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    3. Rosenberg R, Thorpy MJ, Doghramji K, Morse AM. Brain fog in central disorders of hypersomnolence: a review. J Clin Sleep Med. 2024 Jan 13. PMID: 38217475.
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    4. Kaffenberger TM, Chandna M, Kaki P, Corr AM, Plawecki A, Doghramji K, Boon M, Huntley C. Reduced usage of upper airway stimulation therapy in patients with comorbid insomnia and obstructive sleep apnea. J Clin Sleep Med. 2023 Aug 17. PMID: 37589148.
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    5. Benca RM, Krystal A, Chepke C, Doghramji K. Recognition and Management of Obstructive Sleep Apnea in Psychiatric Practice. J Clin Psychiatry. 2023 Jan 23; 84(2). PMID: 36700835.
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    6. Reilly EK, Boon MS, Vimawala S, Chitguppi C, Patel J, Murphy K, Doghramji K, Nyquist GG, Rosen MR, Rabinowitz MR, Huntley CT. Tolerance of Continuous Positive Airway Pressure After Sinonasal Surgery. Laryngoscope. 2020 Sep 16. PMID: 32936959.
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    7. Larsen C, Boyd C, Villwock M, Steffen A, Heiser C, Boon M, Huntley C, Doghramji K, Soose RJ, Kominsky A, Waters T, Withrow K, Parker N, Thaler E, Dhanda Patil R, Green KK, Chio E, Suurna M, Schell A, Strohl K. Evaluation of Surgical Learning Curve Effect on Obstructive Sleep Apnea Outcomes in Upper Airway Stimulation. Ann Otol Rhinol Laryngol. 2020 Sep 13; 3489420958733. PMID: 32924533.
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    8. Mehra R, Steffen A, Heiser C, Hofauer B, Withrow K, Doghramji K, Boon M, Huntley C, Soose RJ, Stevens S, Larsen C, Maurer JT, Waters T, Walia HK, Kominsky AH, Trask D, Schwab RJ, Thaler ER, Strollo PJ. Upper Airway Stimulation versus Untreated Comparators in Positive Airway Pressure Treatment Refractory Obstructive Sleep Apnea. Ann Am Thorac Soc. 2020 Jul 14. PMID: 32663043.
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    9. Zabrecky G, Shahrampour S, Whitely C, Alizadeh M, Conklin C, Wintering N, Doghramji K, Zhan T, Mohamed F, Newberg A, Monti D. An fMRI Study of the Effects of Vibroacoustic Stimulation on Functional Connectivity in Patients with Insomnia. Sleep Disord. 2020; 2020:7846914. PMID: 32089894.
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    10. Tanielian M, Doghramji K, Certa K. Obstructive Sleep Apnea in Psychiatric Inpatients. J Nerv Ment Dis. 2020 Jan 11. PMID: 31929464.
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    11. Thaler E, Schwab R, Maurer J, Soose R, Larsen C, Stevens S, Stevens D, Boon M, Huntley C, Doghramji K, Waters T, Kominsky A, Steffen A, Kezirian E, Hofauer B, Sommer U, Withrow K, Strohl K, Heiser C. Results of the ADHERE upper airway stimulation registry and predictors of therapy efficacy. Laryngoscope. 2019 Sep 14. PMID: 31520484.
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    12. Kezirian EJ, Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose RJ, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen CG, Hsia J, Mehra R, Waters T, Strohl K. Previous Surgery and Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2019 Jun 25; 194599819856339. PMID: 31234734.
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    13. Huntley C, Vasconcellos A, Mullen M, Chou DW, Geosits H, Doghramji K, Boon M. The Impact of Upper Airway Stimulation on Swallowing Function. Ear Nose Throat J. 2019 May 29; 145561319853519. PMID: 31142163.
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    14. Heiser C, Steffen A, Boon M, Hofauer B, Doghramji K, Maurer JT, Sommer JU, Soose R, Strollo PJ, Schwab R, Thaler E, Withrow K, Kominsky A, Larsen C, Kezirian EJ, Hsia J, Chia S, Harwick J, Strohl K, Mehra R. Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry. Eur Respir J. 2019 Jan; 53(1). PMID: 30487205.
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    15. Doghramji K, Tanielian M, Certa K, Zhan T. Severity, Prevalence, Predictors, and Rate of Identification of Insomnia Symptoms in a Sample of Hospitalized Psychiatric Patients. J Nerv Ment Dis. 2018 Oct; 206(10):765-769. PMID: 30273272.
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    16. Huntley C, Topf MC, Christopher V, Doghramji K, Curry J, Boon M. Comparing Upper Airway Stimulation to Transoral Robotic Base of Tongue Resection for Treatment of Obstructive Sleep Apnea. Laryngoscope. 2018 Sep 12. PMID: 30208214.
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    17. Huntley C, Steffen A, Doghramji K, Hofauer B, Heiser C, Boon M. Upper Airway Stimulation in Patients With Obstructive Sleep Apnea and an Elevated Body Mass Index: A Multi-institutional Review. Laryngoscope. 2018 Oct; 128(10):2425-2428. PMID: 30098035.
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    18. Huntley C, Vasconcellos A, Doghramji K, Hofauer B, Heiser C, Boon M. Upper Airway Stimulation in Patients Who Have Undergone Unsuccessful Prior Palate Surgery: An Initial Evaluation. Otolaryngol Head Neck Surg. 2018 Aug 07; 194599818792191. PMID: 30081738.
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    19. Huntley C, Chou DW, Doghramji K, Boon M. Comparing Upper Airway Stimulation to Expansion Sphincter Pharyngoplasty: A Single University Experience. Ann Otol Rhinol Laryngol. 2018 Jun; 127(6):379-383. PMID: 29707958.
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    20. Boon M, Huntley C, Steffen A, Maurer JT, Sommer JU, Schwab R, Thaler E, Soose R, Chou C, Strollo P, Kezirian EJ, Chia S, Withrow K, Weidenbecher M, Strohl K, Doghramji K, Hofauer B, Heiser C. Upper Airway Stimulation for Obstructive Sleep Apnea: Results from the ADHERE Registry. Otolaryngol Head Neck Surg. 2018 Mar 01; 194599818764896. PMID: 29557280.
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    21. Huntley C, Kaffenberger T, Doghramji K, Soose R, Boon M. Upper Airway Stimulation for Treatment of Obstructive Sleep Apnea: An Evaluation and Comparison of Outcomes at Two Academic Centers. J Clin Sleep Med. 2017 Sep 15; 13(9):1075-1079. PMID: 28728614.
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    22. Huntley C, Chou D, Doghramji K, Boon M. Preoperative Drug Induced Sleep Endoscopy Improves the Surgical Approach to Treatment of Obstructive Sleep Apnea. Ann Otol Rhinol Laryngol. 2017 Jun; 126(6):478-482. PMID: 28397553.
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    23. Sharpless BA, Doghramji K. Commentary: How to Make the Ghosts in my Bedroom Disappear? Focused-Attention Meditation Combined with Muscle Relaxation (MR Therapy)-A Direct Treatment Intervention for Sleep Paralysis. Front Psychol. 2017; 8:506. PMID: 28421022.
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    24. Ishii LE, Tollefson TT, Basura GJ, Rosenfeld RM, Abramson PJ, Chaiet SR, Davis KS, Doghramji K, Farrior EH, Finestone SA, Ishman SL, Murphy RX, Park JG, Setzen M, Strike DJ, Walsh SA, Warner JP, Nnacheta LC. Clinical Practice Guideline: Improving Nasal Form and Function after Rhinoplasty Executive Summary. Otolaryngol Head Neck Surg. 2017 Feb; 156(2):205-219. PMID: 28145848.
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    25. Ishii LE, Tollefson TT, Basura GJ, Rosenfeld RM, Abramson PJ, Chaiet SR, Davis KS, Doghramji K, Farrior EH, Finestone SA, Ishman SL, Murphy RX, Park JG, Setzen M, Strike DJ, Walsh SA, Warner JP, Nnacheta LC. Clinical Practice Guideline: Improving Nasal Form and Function after Rhinoplasty. Otolaryngol Head Neck Surg. 2017 Feb; 156(2_suppl):S1-S30. PMID: 28145823.
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    26. Doghramji K, Jangro WC. Adverse Effects of Psychotropic Medications on Sleep. Sleep Med Clin. 2016 Dec; 11(4):503-514. PMID: 28118873.
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    27. Doghramji K, Boon M. The role of upper airway stimulation therapy in the multidisciplinary management approach of obstructive sleep apnea in the adult patient. Laryngoscope. 2016 Sep; 126 Suppl 7:S9-S11. PMID: 27572121.
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    28. Doghramji K, Jangro WC. Adverse Effects of Psychotropic Medications on Sleep. Psychiatr Clin North Am. 2016 Sep; 39(3):487-502. PMID: 27514301.
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    29. Khoury J, Doghramji K. Primary Sleep Disorders. Psychiatr Clin North Am. 2015 Dec; 38(4):683-704. PMID: 26600103.
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    30. Herdman C, Marzio DH, Shah P, Denuna-Rivera S, Doghramji K, Cohen S, Dimarino AJ. Sleep disorders and the prevalence of asymptomatic nocturnal acid and non-acid reflux. Ann Gastroenterol. 2013; 26(3):220-225. PMID: 24714269.
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    31. Doghramji K. Sleep Extension in Sleepy Individuals Reduces Pain Sensitivity: New Evidence Regarding the Complex, Reciprocal Relationship between Sleep and Pain. Sleep. 2012; 35(12):1587-8. PMID: 23204599.
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    32. Vasu TS, Grewal R, Doghramji K. Obstructive sleep apnea syndrome and perioperative complications: a systematic review of the literature. J Clin Sleep Med. 2012 Apr 15; 8(2):199-207. PMID: 22505868.
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    33. Roth T, Bogan RK, Culpepper L, Doghramji K, Doghramji P, Drake C, Grauke JH, Knoepflmacher P, Sateia M, Silvershein D, Thorpy MJ. Excessive sleepiness: under-recognized and essential marker for sleep/wake disorder management. Curr Med Res Opin. 2010 Dec; 26 Suppl 2:S3-24; quiz S25-7. PMID: 21077746.
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    34. Vasu TS, Doghramji K, Cavallazzi R, Grewal R, Hirani A, Leiby B, Markov D, Reiter D, Kraft WK, Witkowski T. Obstructive sleep apnea syndrome and postoperative complications: clinical use of the STOP-BANG questionnaire. Arch Otolaryngol Head Neck Surg. 2010 Oct; 136(10):1020-4. PMID: 20956751.
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    35. Doghramji K. The evaluation and management of insomnia. Clin Chest Med. 2010 Jun; 31(2):327-39. PMID: 20488291.
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    36. Gagliardi GS, Shah AP, Goldstein M, Denua-Rivera S, Doghramji K, Cohen S, Dimarino AJ. Effect of zolpidem on the sleep arousal response to nocturnal esophageal acid exposure. Clin Gastroenterol Hepatol. 2009 Sep; 7(9):948-52. PMID: 19426833.
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    37. Doghramji K. Melatonin and its receptors: a new class of sleep-promoting agents. J Clin Sleep Med. 2007 Aug 15; 3(5 Suppl):S17-23. PMID: 17824497.
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    38. Fava M, Thase ME, DeBattista C, Doghramji K, Arora S, Hughes RJ. Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness. Ann Clin Psychiatry. 2007 Jul-Sep; 19(3):153-9. PMID: 17729016.
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    39. Bonnet MH, Doghramji K, Roehrs T, Stepanski EJ, Sheldon SH, Walters AS, Wise M, Chesson AL. The scoring of arousal in sleep: reliability, validity, and alternatives. J Clin Sleep Med. 2007 Mar 15; 3(2):133-45. PMID: 17557423.
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    40. Zammit GK, Corser B, Doghramji K, Fry JM, James S, Krystal A, Mangano RM. Sleep and residual sedation after administration of zaleplon, zolpidem, and placebo during experimental middle-of-the-night awakening. J Clin Sleep Med. 2006 Oct 15; 2(4):417-23. PMID: 17557470.
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    41. Jaffe F, Markov D, Doghramji K. Sleep-disordered breathing: in depression and schizophrenia. Psychiatry (Edgmont). 2006 Jul; 3(7):62-8. PMID: 20975818.
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    42. Markov D, Jaffe F, Doghramji K. Update on parasomnias: a review for psychiatric practice. Psychiatry (Edgmont). 2006 Jul; 3(7):69-76. PMID: 20975819.
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    43. Doghramji K. The epidemiology and diagnosis of insomnia. Am J Manag Care. 2006 May; 12(8 Suppl):S214-20. PMID: 16686591.
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    44. Pinninti NR, Mago R, Townsend J, Doghramji K. Periodic restless legs syndrome associated with quetiapine use: a case report. J Clin Psychopharmacol. 2005 Dec; 25(6):617-8. PMID: 16282854.
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    45. Dimarino Jr AJ, Banwait KS, Eschinger E, Greenberg A, Dimarino M, Doghramji K, Cohen S. The effect of gastro-oesophageal reflux and omeprazole on key sleep parameters. Aliment Pharmacol Ther. 2005 Aug 15; 22(4):325-9. PMID: 16097999.
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    46. Edinger JD, Bonnet MH, Bootzin RR, Doghramji K, Dorsey CM, Espie CA, Jamieson AO, McCall WV, Morin CM, Stepanski EJ. Derivation of research diagnostic criteria for insomnia: report of an American Academy of Sleep Medicine Work Group. Sleep. 2004 Dec 15; 27(8):1567-96. PMID: 15683149.
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    47. Doghramji K. Assessment of excessive sleepiness and insomnia as they relate to circadian rhythm sleep disorders. J Clin Psychiatry. 2004; 65 Suppl 16:17-22. PMID: 15575800.
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    48. DeBattista C, Doghramji K, Menza MA, Rosenthal MH, Fieve RR. Adjunct modafinil for the short-term treatment of fatigue and sleepiness in patients with major depressive disorder: a preliminary double-blind, placebo-controlled study. J Clin Psychiatry. 2003 Sep; 64(9):1057-64. PMID: 14628981.
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    49. Doghramji K. Treatment strategies for sleep disturbance in patients with depression. J Clin Psychiatry. 2003; 64 Suppl 14:24-9. PMID: 14658932.
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    50. Roth T, Zammit G, Kushida C, Doghramji K, Mathias SD, Wong JM, Buysse DJ. A new questionnaire to detect sleep disorders. Sleep Med. 2002 Mar; 3(2):99-108. PMID: 14592227.
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    51. Menefee LA, Frank ED, Doghramji K, Picarello K, Park JJ, Jalali S, Perez-Schwartz L. Self-reported sleep quality and quality of life for individuals with chronic pain conditions. Clin J Pain. 2000 Dec; 16(4):290-7. PMID: 11153783.
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    52. Menefee LA, Cohen MJ, Anderson WR, Doghramji K, Frank ED, Lee H. Sleep disturbance and nonmalignant chronic pain: a comprehensive review of the literature. Pain Med. 2000 Jun; 1(2):156-72. PMID: 15101904.
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    53. Sateia MJ, Doghramji K, Hauri PJ, Morin CM. Evaluation of chronic insomnia. An American Academy of Sleep Medicine review. Sleep. 2000 Mar 15; 23(2):243-308. PMID: 10737342.
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    54. Doghramji K. The need for flexibility in dosing of hypnotic agents. Sleep. 2000 Feb 1; 23 Suppl 1:S16-20; discussion S21-2. PMID: 10755804.
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    55. Pribitkin EA, Schutte SL, Keane WM, Mao V, Cater JR, Doghramji K, Youakim JM, Rosen MR, Breuninger W. Efficacy of laser-assisted uvulopalatoplasty in obstructive sleep apnea. Otolaryngol Head Neck Surg. 1998 Dec; 119(6):643-7. PMID: 9852540.
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    56. Rosen R, Mahowald M, Chesson A, Doghramji K, Goldberg R, Moline M, Millman R, Zammit G, Mark B, Dement W. The Taskforce 2000 survey on medical education in sleep and sleep disorders. Sleep. 1998 May 1; 21(3):235-8. PMID: 9595601.
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    57. Youakim JM, Doghramji K, Schutte SL. Posttraumatic stress disorder and obstructive sleep apnea syndrome. Psychosomatics. 1998 Mar-Apr; 39(2):168-71. PMID: 9584544.
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    58. Doghramji K, Mitler MM, Sangal RB, Shapiro C, Taylor S, Walsleben J, Belisle C, Erman MK, Hayduk R, Hosn R, O'Malley EB, Sangal JM, Schutte SL, Youakim JM. A normative study of the maintenance of wakefulness test (MWT). Electroencephalogr Clin Neurophysiol. 1997 Nov; 103(5):554-62. PMID: 9402886.
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    59. Doghramji K, Jabourian ZH, Pilla M, Farole A, Lindholm RN. Predictors of outcome for uvulopalatopharyngoplasty. Laryngoscope. 1995 Mar; 105(3 Pt 1):311-4. PMID: 7877422.
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    60. Doghramji K, Browman CP, Gaddy JR, Walsh JK. Triazolam diminishes daytime sleepiness and sleep fragmentation in patients with periodic leg movements in sleep. J Clin Psychopharmacol. 1991 Oct; 11(5):284-90. PMID: 1765571.
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    61. Doghramji K, Gaddy JR, Stewart KT, Rosenthal NE, Brainard GC. 2- versus 4-hour evening phototherapy of seasonal affective disorder. J Nerv Ment Dis. 1990 Apr; 178(4):257-60. PMID: 2319234.
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    62. Doghramji K. Causes, pathogenesis, and management of sleep disorders. Compr Ther. 1990 Mar; 16(3):49-59. PMID: 2180629.
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    63. Byrne B, Nino-Murcia G, Gaddy JR, Doghramji K, Keenan S. Sleep patterns and dexamethasone suppression in nondepressed bulimics. Biol Psychiatry. 1990 Feb 15; 27(4):454-6. PMID: 2178694.
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    64. Gaddy JR, Stewart KT, Byrne B, Doghramji K, Rollag MD, Brainard GC. Light-induced plasma melatonin suppression in seasonal affective disorder. Prog Neuropsychopharmacol Biol Psychiatry. 1990; 14(4):563-8. PMID: 2236583.
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    65. Doghramji K. Sleep disorders: a selective update. Hosp Community Psychiatry. 1989 Jan; 40(1):29-40. PMID: 2643552.
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    66. Ellis DJ, Doghramji K, Bagley DH. Snap-Gauge band versus penile rigidity in impotence assessment. J Urol. 1988 Jul; 140(1):61-3. PMID: 3379699.
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    67. Akhtar S, Byrne JP, Doghramji K. The demographic profile of borderline personality disorder. J Clin Psychiatry. 1986 Apr; 47(4):196-8. PMID: 3957879.
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