Thomas Jefferson University

Laurence Eisenlohr

TitleAssoc Prof CHP
InstitutionThomas Jefferson University
DepartmentNursing - Undergraduate
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-4540
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    Collapse Research 
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    T32CA009683     (EISENLOHR, LAURENCE CRANE)Feb 5, 1993 - Jul 31, 2009
    NIH
    TRAINING PROGRAM IN CANCER IMMUNOLOGY
    Role: Principal Investigator
    R01AI036331     (EISENLOHR, LAURENCE CRANE)Apr 1, 1995 - Apr 30, 2010
    NIH
    Class II Processing Delineated by Flu Glycoproteins
    Role: Principal Investigator
    R01AI039501     (EISENLOHR, LAURENCE CRANE)Jun 1, 1997 - Dec 31, 2012
    NIH
    Accessing the MHC Class I Processing Pathway
    Role: Principal Investigator
    R01AI046511     (EISENLOHR, LAURENCE CRANE)Apr 1, 2000 - Mar 31, 2005
    NIH
    IMPACT OF EPITOPE DENSITY ON TCD8, ACTIVATION AND MEMORY
    Role: Principal Investigator
    R21AI063065     (EISENLOHR, LAURENCE CRANE)Apr 1, 2006 - Mar 31, 2009
    NIH
    The Role of the RET Receptor in Autoimmune Disease
    Role: Principal Investigator
    R01AI069192     (EISENLOHR, LAURENCE CRANE)Jan 8, 2007 - Dec 31, 2011
    NIH
    The Basis for MHC Class II-restricted proteasome-dependent epitopes
    Role: Principal Investigator
    R21AI077053     (EISENLOHR, LAURENCE CRANE)Sep 1, 2007 - Aug 31, 2009
    NIH
    Dissecting 3 processing pathways that generate class II-restricted flu epitopes
    Role: Principal Investigator
    R21AI079526     (EISENLOHR, LAURENCE CRANE)Jun 20, 2008 - May 31, 2011
    NIH
    Non-proteasomal protease(s) that define C-termini of MHC class I epitopes
    Role: Principal Investigator
    R21CA135602     (EISENLOHR, LAURENCE CRANE)Jul 1, 2008 - Dec 31, 2011
    NIH
    Dynamics of tolerance induction to tumor associated antigens
    Role: Principal Investigator
    R01AI100561     (EISENLOHR, LAURENCE CRANE)Feb 1, 2012 - Sep 30, 2017
    NIH
    Antigen stability as a parameter in rational T(CD8+)-targeting vaccine design
    Role: Principal Investigator
    R21AI101929     (EISENLOHR, LAURENCE CRANE)Jul 3, 2012 - Jun 30, 2015
    NIH
    The RET/PTC3 Oncogene: Antigenic and Inflammatory Properties
    Role: Principal Investigator
    R56AI101134     (EISENLOHR, LAURENCE CRANE)Aug 1, 2013 - Jul 31, 2015
    NIH
    Alternative Pathways for CD4+ T Cell Epitope Generation from Influenza Antigens
    Role: Principal Investigator
    R01AI113286     (EISENLOHR, LAURENCE CRANE)Jun 15, 2014 - May 31, 2021
    NIH
    Alternative MHCII Processing of Influenza Virus Proteins
    Role: Principal Investigator
    R21AI110848     (EISENLOHR, LAURENCE CRANE)Dec 1, 2014 - Nov 30, 2017
    NIH
    Class II Processing and Presentation During Secondary Responses to Influenza
    Role: Principal Investigator
    R01AI110542     (EISENLOHR, LAURENCE CRANE)Jul 15, 2015 - Dec 31, 2020
    NIH
    MHCII Cross-presentation as a Driver of CD4+ T Cell Responses to Poxviruses
    Role: Principal Investigator
    R21AI135567     (EISENLOHR, LAURENCE CRANE)Dec 13, 2017 - Nov 30, 2020
    NIH
    Major contribution of non-classical antigen processing to Salmonella Typhimurium-specific CD4+ T cell responses
    Role: Principal Investigator
    R21AI141110     (EISENLOHR, LAURENCE CRANE)Aug 15, 2018 - Jul 31, 2021
    NIH
    Defining the MHC-II processing and presentation landscape of HIV-1
    Role: Principal Investigator
    R21AI153978     (EISENLOHR, LAURENCE CRANE)Jun 1, 2020 - May 31, 2022
    NIH
    Delineating the non-conventional MHC class I and class II peptidome of influenza
    Role: Principal Investigator
    R21AI160063     (EISENLOHR, LAURENCE CRANE)Mar 5, 2021 - Feb 28, 2023
    NIH
    Targeting of RAG-dependent and -independent innate immune responses by the Ectromelia C15 protein
    Role: Principal Investigator
    R01AI182049     (EISENLOHR, LAURENCE CRANE)Feb 6, 2024 - Dec 31, 2028
    NIH
    The B22 family of orthopoxvirus virulence factors: Investigating structure/function of these potent, multifaceted immunoevasins
    Role: Principal Investigator
    R01AI180250     (EISENLOHR, LAURENCE CRANE)Jun 1, 2024 - Apr 30, 2029
    NIH
    Defining the four major routes of MHC class II antigen processing and presentation with influenza antigens
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Goodwin E, Gibbs JS, Yewdell JW, Eisenlohr LC, Hensley SE. Influenza virus antibodies inhibit antigen-specific de novo B cell responses in mice. J Virol. 2024 Aug 28; e0076624. PMID: 39194245.
      Citations:    
    2. Clements RL, Kennedy EA, Song D, Campbell A, An HH, Amses KR, Miller-Ensminger T, Addison MM, Eisenlohr LC, Chou ST, Jurado KA. Human erythroid progenitors express antigen presentation machinery. bioRxiv. 2024 Jul 01. PMID: 39005276.
      Citations:    
    3. Goodwin E, Gibbs JS, Yewdell JW, Eisenlohr LC, Hensley SE. Influenza virus antibodies inhibit antigen-specific de novo B cell responses in mice. bioRxiv. 2024 Apr 15. PMID: 38659819.
      Citations:    
    4. Liao H, Barra C, Zhou Z, Peng X, Woodhouse I, Tailor A, Parker R, Carr? A, Borrow P, Hogan MJ, Paes W, Eisenlohr LC, Mallone R, Nielsen M, Ternette N. MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer. Nat Commun. 2024 Jan 22; 15(1):661. PMID: 38253617.
      Citations:    
    5. Yarmarkovich M, Marshall QF, Warrington JM, Premaratne R, Farrel A, Groff D, Li W, di Marco M, Runbeck E, Truong H, Toor JS, Tripathi S, Nguyen S, Shen H, Noel T, Church NL, Weiner A, Kendsersky N, Martinez D, Weisberg R, Christie M, Eisenlohr L, Bosse KR, Dimitrov DS, Stevanovic S, Sgourakis NG, Kiefel BR, Maris JM. Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature. 2023 Nov 08. PMID: 37938785.
      Citations:    
    6. Yarmarkovich M, Marshall QF, Warrington JM, Premaratne R, Farrel A, Groff D, Li W, di Marco M, Runbeck E, Truong H, Toor JS, Tripathi S, Nguyen S, Shen H, Noel T, Church NL, Weiner A, Kendsersky N, Martinez D, Weisberg R, Christie M, Eisenlohr L, Bosse KR, Dimitrov DS, Stevanovic S, Sgourakis NG, Kiefel BR, Maris JM. Targeting of intracellular oncoproteins with peptide-centric CARs. Nature. 2023 Nov; 623(7988):820-827. PMID: 37938771.
      Citations:    
    7. Dar AA, Kim DD, Gordon SM, Klinzing K, Rosen S, Guha I, Porter N, Ortega Y, Forsyth KS, Roof J, Fazelinia H, Spruce LA, Eisenlohr LC, Behrens EM, Oliver PM. c-Myc uses Cul4b to preserve genome integrity and promote antiviral CD8+ T cell immunity. Nat Commun. 2023 Nov 04; 14(1):7098. PMID: 37925424.
      Citations:    
    8. Hogan MJ, Maheshwari N, Begg BE, Nicastri A, Hedgepeth EJ, Muramatsu H, Pardi N, Miller MA, Reilly SP, Brossay L, Lynch KW, Ternette N, Eisenlohr LC. Cryptic MHC-E epitope from influenza elicits a potent cytolytic T cell response. Nat Immunol. 2023 Oct 12. PMID: 37828378.
      Citations:    
    9. Peauroi EM, Carro SD, Pei L, Reynoso GV, Hickman HD, Eisenlohr LC. The ectromelia virus virulence factor C15 facilitates early viral spread by inhibiting NK cell contact. iScience. 2022 Dec 22; 25(12):105510. PMID: 36425759.
      Citations:    
    10. Addison MM, Ellis GI, Leslie GJ, Zawadzky NB, Riley JL, Hoxie JA, Eisenlohr LC. HIV-1-Infected CD4+ T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing. J Immunol. 2022 09 01; 209(5):864-873. PMID: 36130133.
      Citations:    
    11. Ghosh D, Pham TD, Nanaware PP, Sengupta D, Adler LN, Li CG, He X, O'Mara ME, Kantor AB, Nguyen KD, Yang Y, Eisenlohr LC, Jensen PE, Herzenberg LA, Stern LJ, Boyd SD, Ghosn EEB, Mellins ED. Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells. Cell Rep. 2022 01 25; 38(4):110200. PMID: 35081339.
      Citations:    
    12. Yarmarkovich M, Marshall QF, Warrington JM, Premaratne R, Farrel A, Groff D, Li W, di Marco M, Runbeck E, Truong H, Toor JS, Tripathi S, Nguyen S, Shen H, Noel T, Church NL, Weiner A, Kendsersky N, Martinez D, Weisberg R, Christie M, Eisenlohr L, Bosse KR, Dimitrov DS, Stevanovic S, Sgourakis NG, Kiefel BR, Maris JM. Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature. 2021 11; 599(7885):477-484. PMID: 34732890.
      Citations:    
    13. Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993. PMID: 34183650.
      Citations:    
    14. Lederer K, Castaño D, Gómez Atria D, Oguin TH, Wang S, Manzoni TB, Muramatsu H, Hogan MJ, Amanat F, Cherubin P, Lundgreen KA, Tam YK, Fan SHY, Eisenlohr LC, Maillard I, Weissman D, Bates P, Krammer F, Sempowski GD, Pardi N, Locci M. SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation. Immunity. 2020 12 15; 53(6):1281-1295.e5. PMID: 33296685.
      Citations:    
    15. Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020 10; 22(10):1197-1210. PMID: 32989251.
      Citations:    
    16. Forsyth KS, Roy NH, Peauroi E, DeHaven BC, Wold ED, Hersperger AR, Burkhardt JK, Eisenlohr LC. Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+ T cells post peptide loading. PLoS Pathog. 2020 Aug; 16(8):e1008685. PMID: 32745153.
      Citations:    
    17. Laczkó D, Hogan MJ, Toulmin SA, Hicks P, Lederer K, Gaudette BT, Castaño D, Amanat F, Muramatsu H, Oguin TH, Ojha A, Zhang L, Mu Z, Parks R, Manzoni TB, Roper B, Strohmeier S, Tombácz I, Arwood L, Nachbagauer R, Karikó K, Greenhouse J, Pessaint L, Porto M, Putman-Taylor T, Strasbaugh A, Campbell TA, Lin PJC, Tam YK, Sempowski GD, Farzan M, Choe H, Saunders KO, Haynes BF, Andersen H, Eisenlohr LC, Weissman D, Krammer F, Bates P, Allman D, Locci M, Pardi N. A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity. 2020 Jul 30. PMID: 32783919.
      Citations:    
    18. Cosma GL, Lobby JL, Fay EJ, Siciliano NA, Langlois RA, Eisenlohr LC. Kinetically distinct processing pathways diversify the CD8+ T cell response to a single viral epitope. Proc Natl Acad Sci U S A. 2020 Aug 11; 117(32):19399-19407. PMID: 32719124.
      Citations:    
    19. Cho KJ, Ishido S, Eisenlohr LC, Roche PA. Activation of Dendritic Cells Alters the Mechanism of MHC Class II Antigen Presentation to CD4 T Cells. J Immunol. 2020 Jan 29. PMID: 31996461.
      Citations:    
    20. Lang JF, Toulmin SA, Brida KL, Eisenlohr LC, Davidson BL. Standard screening methods underreport AAV-mediated transduction and gene editing. Nat Commun. 2019 Jul 30; 10(1):3415. PMID: 31363095.
      Citations:    
    21. Cosma GL, Eisenlohr LC. Impact of epitope density on CD8+ T cell development and function. Mol Immunol. 2019 Apr 01. PMID: 30948189.
      Citations:    
    22. Forsyth KS, DeHaven B, Mendonca M, Paul S, Sette A, Eisenlohr LC. Poor Antigen Processing of Poxvirus Particles Limits CD4+ T Cell Recognition and Impacts Immunogenicity of the Inactivated Vaccine. J Immunol. 2019 Mar 01; 202(5):1340-1349. PMID: 30700590.
      Citations:    
    23. Forsyth KS, Addison MM, Eisenlohr LC. Recombinant Poxviruses: Versatile Tools for Immunological Assays. Methods Mol Biol. 2019; 1988:217-248. PMID: 31147943.
      Citations:    
    24. Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. J Exp Med. 2018 Jun 04; 215(6):1571-1588. PMID: 29739835.
      Citations:    
    25. Cosma G, Eisenlohr L. CD8 + T-cell responses in vaccination: reconsidering targets and function in the context of chronic antigen stimulation. F1000Res. 2018; 7. PMID: 29770202.
      Citations:    
    26. Frey TR, Forsyth KS, Sheehan MM, De Haven BC, Pevarnik JG, Hand ES, Pizzorno MC, Eisenlohr LC, Hersperger AR. Ectromelia virus lacking the E3L ortholog is replication-defective and nonpathogenic but does induce protective immunity in a mouse strain susceptible to lethal mousepox. Virology. 2018 05; 518:335-348. PMID: 29602068.
      Citations:    
    27. Tomov VT, Palko O, Lau CW, Pattekar A, Sun Y, Tacheva R, Bengsch B, Manne S, Cosma GL, Eisenlohr LC, Nice TJ, Virgin HW, Wherry EJ. Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche. Immunity. 2017 Oct 17; 47(4):723-738.e5. PMID: 29031786.
      Citations:    
    28. Babushok DV, Duke JL, Xie HM, Stanley N, Atienza J, Perdigones N, Nicholas P, Ferriola D, Li Y, Huang H, Ye W, Morrissette JJD, Kearns J, Porter DL, Podsakoff GM, Eisenlohr LC, Biegel JA, Chou ST, Monos DS, Bessler M, Olson TS. Somatic HLA Mutations Expose the Role of Class I-Mediated Autoimmunity in Aplastic Anemia and its Clonal Complications. Blood Adv. 2017 Oct 10; 1(22):1900-1910. PMID: 28971166.
      Citations:    
    29. Veerappan Ganesan AP, Eisenlohr LC. The elucidation of non-classical MHC class II antigen processing through the study of viral antigens. Curr Opin Virol. 2017 Feb; 22:71-76. PMID: 28081485.
      Citations:    
    30. Norbury CC, Eisenlohr LC. Editorial overview: Antigen processing. Curr Opin Immunol. 2016 Jun; 40:v-vi. PMID: 27178764.
      Citations:    
    31. Forsyth KS, Eisenlohr LC. Giving CD4+ T cells the slip: viral interference with MHC class II-restricted antigen processing and presentation. Curr Opin Immunol. 2016 Jun; 40:123-9. PMID: 27115617.
      Citations:    
    32. Miller MA, Ganesan AP, Luckashenak N, Mendonca M, Eisenlohr LC. Endogenous antigen processing drives the primary CD4(+) T cell response to influenza. Nat Med. 2015 Oct; 21(10):1216-22. PMID: 26413780.
      Citations:    
    33. Eisenlohr LC, Denzin LK. Cretaceous collegiality. Mol Immunol. 2015 Dec; 68(2 Pt A):67. PMID: 26359187.
      Citations:    
    34. Siciliano NA, Hersperger AR, Lacuanan AM, Xu RH, Sidney J, Sette A, Sigal LJ, Eisenlohr LC. Impact of Distinct Poxvirus Infections on the Specificities and Functionalities of CD4+ T Cell Responses. J Virol. 2014 Sep 1; 88(17):10078-91. PMID: 24965457.
      Citations:    
    35. Hersperger AR, Siciliano NA, DeHaven BC, Snook AE, Eisenlohr LC. Epithelial Immunization Induces Polyfunctional CD8+ T Cells and Optimal Mousepox Protection. J Virol. 2014 Aug 15; 88(16):9472-5. PMID: 24899206.
      Citations:    
    36. Walline CC, Deffit SN, Wang N, Guindon LM, Crotzer VL, Liu J, Hollister K, Eisenlohr LC, Brutkiewicz RR, Kaplan MH, Blum JS. Virus-encoded ectopic CD74 enhances poxvirus vaccine efficacy. Immunology. 2014 Apr; 141(4):531-9. PMID: 24205828.
      Citations:    
    37. Goodenough E, Robinson TM, Zook MB, Flanigan KM, Atkins JF, Howard MT, Eisenlohr LC. Cryptic MHC class I-binding peptides are revealed by aminoglycoside-induced stop codon read-through into the 3' UTR. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5670-5. PMID: 24706797.
      Citations:    
    38. Davies ML, Sei JJ, Siciliano NA, Xu RH, Roscoe F, Sigal LJ, Eisenlohr LC, Norbury CC. MyD88-Dependent Immunity to a Natural Model of Vaccinia Virus Infection Does Not Involve Toll-Like Receptor 2. J Virol. 2014 Mar; 88(6):3557-67. PMID: 24403581.
      Citations:    
    39. Miller MA, Ganesan AP, Eisenlohr LC. Toward a Network Model of MHC Class II-Restricted Antigen Processing. Front Immunol. 2013; 4:464. PMID: 24379819.
      Citations:    
    40. Siciliano NA, Huang L, Eisenlohr LC. Recombinant poxviruses: versatile tools for immunological assays. Methods Mol Biol. 2013; 960:219-45. PMID: 23329491.
      Citations:    
    41. Eisenlohr LC. Alternative generation of MHC class II-restricted epitopes: Not so exceptional? Mol Immunol. 2013 Sep; 55(2):169-71. PMID: 23200635.
      Citations:    
    42. Fang M, Siciliano NA, Hersperger AR, Roscoe F, Hu A, Ma X, Shamsedeen AR, Eisenlohr LC, Sigal LJ. Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):9983-8. PMID: 22665800.
      Citations:    
    43. Hersperger AR, Siciliano NA, Eisenlohr LC. Comparable polyfunctionality of ectromelia virus- and vaccinia virus-specific murine T cells despite markedly different in vivo replication and pathogenicity. J Virol. 2012 Jul; 86(13):7298-309. PMID: 22532670.
      Citations:    
    44. Wixted JH, Rothstein JL, Eisenlohr LC. Identification of functionally distinct TRAF proinflammatory and phosphatidylinositol 3-kinase/mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (PI3K/MEK) transforming activities emanating from RET/PTC fusion oncoprotein. J Biol Chem. 2012 Feb 3; 287(6):3691-703. PMID: 22158616.
      Citations:    
    45. Eisenlohr LC, Luckashenak N, Apcher S, Miller MA, Sinnathamby G. Beyond the classical: influenza virus and the elucidation of alternative MHC class II-restricted antigen processing pathways. Immunol Res. 2011 Dec; 51(2-3):237-48. PMID: 22101673.
      Citations:    
    46. Comber JD, Robinson TM, Siciliano NA, Snook AE, Eisenlohr LC. Functional macroautophagy induction by influenza A virus without a contribution to major histocompatibility complex class II-restricted presentation. J Virol. 2011 Jul; 85(13):6453-63. PMID: 21525345.
      Citations:    
    47. Huang L, Kuhls MC, Eisenlohr LC. Hydrophobicity as a driver of MHC class I antigen processing. EMBO J. 2011 Apr 20; 30(8):1634-44. PMID: 21378750.
      Citations:    
    48. Huang L, Marvin JM, Tatsis N, Eisenlohr LC. Cutting Edge: Selective role of ubiquitin in MHC class I antigen presentation. J Immunol. 2011 Feb 15; 186(4):1904-8. PMID: 21239720.
      Citations:    
    49. Testa JS, Apcher GS, Comber JD, Eisenlohr LC. Exosome-driven antigen transfer for MHC class II presentation facilitated by the receptor binding activity of influenza hemagglutinin. J Immunol. 2010 Dec 1; 185(11):6608-16. PMID: 21048109.
      Citations:    
    50. Fernandes-Alnemri T, Yu JW, Juliana C, Solorzano L, Kang S, Wu J, Datta P, McCormick M, Huang L, McDermott E, Eisenlohr L, Landel CP, Alnemri ES. The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol. 2010 May; 11(5):385-93. PMID: 20351693.
      Citations:    
    51. Snook AE, Li P, Stafford BJ, Faul EJ, Huang L, Birbe RC, Bombonati A, Schulz S, Schnell MJ, Eisenlohr LC, Waldman SA. Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease. Cancer Res. 2009 Apr 15; 69(8):3537-44. PMID: 19351847.
      Citations:    
    52. Snook AE, Huang L, Schulz S, Eisenlohr LC, Waldman SA. Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens. Clin Transl Sci. 2008 Dec; 1(3):263-4. PMID: 19956776.
      Citations:    
    53. Snook AE, Stafford BJ, Li P, Tan G, Huang L, Birbe R, Schulz S, Schnell MJ, Thakur M, Rothstein JL, Eisenlohr LC, Waldman SA. Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity. J Natl Cancer Inst. 2008 Jul 2; 100(13):950-61. PMID: 18577748.
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    54. Plesa G, Snook AE, Waldman SA, Eisenlohr LC. Derivation and fluidity of acutely induced dysfunctional CD8+ T cells. J Immunol. 2008 Apr 15; 180(8):5300-8. PMID: 18390711.
      Citations:    
    55. Snook AE, Stafford BJ, Eisenlohr LC, Rothstein JL, Waldman SA. Mucosally restricted antigens as novel immunological targets for antitumor therapy. Biomark Med. 2007 Jun; 1(1):187-202. PMID: 20477468.
      Citations:    
    56. Eisenlohr LC, Huang L, Golovina TN. Rethinking peptide supply to MHC class I molecules. Nat Rev Immunol. 2007 May; 7(5):403-10. PMID: 17457346.
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    57. Tang J, Murtadha M, Schnell M, Eisenlohr LC, Hooper J, Flomenberg P. Human T-cell responses to vaccinia virus envelope proteins. J Virol. 2006 Oct; 80(20):10010-20. PMID: 17005679.
      Citations:    
    58. Plesa G, McKenna PM, Schnell MJ, Eisenlohr LC. Immunogenicity of cytopathic and noncytopathic viral vectors. J Virol. 2006 Jul; 80(13):6259-66. PMID: 16775313.
      Citations:    
    59. Zook MB, Howard MT, Sinnathamby G, Atkins JF, Eisenlohr LC. Epitopes derived by incidental translational frameshifting give rise to a protective CTL response. J Immunol. 2006 Jun 1; 176(11):6928-34. PMID: 16709853.
      Citations:    
    60. Eisenlohr LC, Rothstein JL. Oncogenic inflammation and autoimmune disease. Autoimmun Rev. 2006 Dec; 6(2):107-14. PMID: 17138254.
      Citations:    
    61. Tang J, Olive M, Pulmanausahakul R, Schnell M, Flomenberg N, Eisenlohr L, Flomenberg P. Human CD8+ cytotoxic T cell responses to adenovirus capsid proteins. Virology. 2006 Jul 5; 350(2):312-22. PMID: 16499941.
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    62. Wherry EJ, Golovina TN, Morrison SE, Sinnathamby G, McElhaugh MJ, Shockey DC, Eisenlohr LC. Re-evaluating the generation of a "proteasome-independent" MHC class I-restricted CD8 T cell epitope. J Immunol. 2006 Feb 15; 176(4):2249-61. PMID: 16455981.
      Citations:    
    63. McGettigan JP, Koser ML, McKenna PM, Smith ME, Marvin JM, Eisenlohr LC, Dietzschold B, Schnell MJ. Enhanced humoral HIV-1-specific immune responses generated from recombinant rhabdoviral-based vaccine vectors co-expressing HIV-1 proteins and IL-2. Virology. 2006 Jan 20; 344(2):363-77. PMID: 16226782.
      Citations:    
    64. Lefebvre JM, Haks MC, Carleton MO, Rhodes M, Sinnathamby G, Simon MC, Eisenlohr LC, Garrett-Sinha LA, Wiest DL. Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection. J Immunol. 2005 May 15; 174(10):6184-94. PMID: 15879115.
      Citations:    
    65. Golovina TN, Morrison SE, Eisenlohr LC. The impact of misfolding versus targeted degradation on the efficiency of the MHC class I-restricted antigen processing. J Immunol. 2005 Mar 1; 174(5):2763-9. PMID: 15728485.
      Citations:    
    66. Tewari MK, Sinnathamby G, Rajagopal D, Eisenlohr LC. A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent. Nat Immunol. 2005 Mar; 6(3):287-94. PMID: 15711549.
      Citations:    
    67. Eisenlohr LC, Rothstein JL. Antigen processing and presentation. Cancer Treat Res. 2005; 123:3-36. PMID: 16211864.
      Citations:    
    68. Sinnathamby G, Maric M, Cresswell P, Eisenlohr LC. Differential requirements for endosomal reduction in the presentation of two H2-E(d)-restricted epitopes from influenza hemagglutinin. J Immunol. 2004 Jun 1; 172(11):6607-14. PMID: 15153475.
      Citations:    
    69. Tatsis N, Sinnathamby G, Eisenlohr LC. Vaccinia virus as a tool for immunologic studies. Methods Mol Biol. 2004; 269:267-88. PMID: 15114021.
      Citations:    
    70. Sinnathamby G, Eisenlohr LC. Presentation by recycling MHC class II molecules of an influenza hemagglutinin-derived epitope that is revealed in the early endosome by acidification. J Immunol. 2003 Apr 1; 170(7):3504-13. PMID: 12646611.
      Citations:    
    71. Spierings E, Brickner AG, Caldwell JA, Zegveld S, Tatsis N, Blokland E, Pool J, Pierce RA, Mollah S, Shabanowitz J, Eisenlohr LC, van Veelen P, Ossendorp F, Hunt DF, Goulmy E, Engelhard VH. The minor histocompatibility antigen HA-3 arises from differential proteasome-mediated cleavage of the lymphoid blast crisis (Lbc) oncoprotein. Blood. 2003 Jul 15; 102(2):621-9. PMID: 12663445.
      Citations:    
    72. Powell DJ, Eisenlohr LC, Rothstein JL. A thyroid tumor-specific antigen formed by the fusion of two self proteins. J Immunol. 2003 Jan 15; 170(2):861-9. PMID: 12517951.
      Citations:    
    73. Olive M, Eisenlohr L, Flomenberg N, Hsu S, Flomenberg P. The adenovirus capsid protein hexon contains a highly conserved human CD4+ T-cell epitope. Hum Gene Ther. 2002 Jul 1; 13(10):1167-78. PMID: 12133270.
      Citations:    
    74. Wherry EJ, McElhaugh MJ, Eisenlohr LC. Generation of CD8(+) T cell memory in response to low, high, and excessive levels of epitope. J Immunol. 2002 May 1; 168(9):4455-61. PMID: 11970989.
      Citations:    
    75. Golovina TN, Wherry EJ, Bullock TN, Eisenlohr LC. Efficient and qualitatively distinct MHC class I-restricted presentation of antigen targeted to the endoplasmic reticulum. J Immunol. 2002 Mar 15; 168(6):2667-75. PMID: 11884431.
      Citations:    
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