Lawrence Kenyon

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentPathology
Address132 S. 10th St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Prosniak M, Harshyne LA, Gorky J, Curtis MT, Kenyon LC, Schwaber JS, Lebrun A, Kean RB, Andrews DW, Hooper DC. Systemic Immune Bias Delineates Malignant Astrocytoma Survival Cohorts. J Immunol. 2021 Apr 01; 206(7):1483-1492. PMID: 33685995.
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    2. Andrews DW, Judy KD, Scott CB, Garcia S, Harshyne LA, Kenyon L, Talekar K, Flanders A, Atsina KB, Kim L, Martinez N, Shi W, Werner-Wasik M, Liu H, Prosniak M, Curtis M, Kean R, Ye DY, Bongiorno E, Sauma S, Exley MA, Pigott K, Hooper DC. Phase Ib Clinical Trial of IGV-001 for Patients with Newly Diagnosed Glioblastoma. Clin Cancer Res. 2021 Apr 01; 27(7):1912-1922. PMID: 33500356.
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    3. Fernandez C, Hoeltzel G, Werner-Wasik M, Kenyon LC, Shi W. Definitive radiotherapy for meningeal brainstem melanocytoma: a case report. Br J Neurosurg. 2020 Dec 26; 1-4. PMID: 33356599.
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    4. Fernandez C, Cappelli L, Chapin S, Kenyon L, Farrell CJ, Shi W. Breast carcinoma metastasis in a resected meningioma with early diagnosis of oligometastatic disease: a case report. Chin Clin Oncol. 2020 Oct; 9(5):71. PMID: 33161726.
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    5. Chakravarty D, Saadi F, Kundu S, Bose A, Khan R, Dine K, Kenyon LC, Shindler KS, Das Sarma J. CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation. J Virol. 2020 Jul 01; 94(14). PMID: 32404525.
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    6. Norton EJ, Bridges LR, Kenyon LC, Esiri MM, Bennett DC, Hainsworth AH. Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older. J Neuropathol Exp Neurol. 2019 Aug 28. PMID: 31553444.
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    7. D'Almeida Costa F, Dias TM, Lombardo KA, Raghunathan A, Giannini C, Kenyon L, Saad AG, Gokden M, Burger PC, Montgomery EA, Rodriguez FJ. Intracranial Cellular Schwannomas: A Clinicopathologic Study of 20 Cases. Histopathology. 2019 Aug 04. PMID: 31379028.
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    8. Singh M, Kishore A, Maity D, Sunanda P, Krishnarjuna B, Vappala S, Raghothama S, Kenyon LC, Pal D, Das Sarma J. A proline insertion-deletion in the spike glycoprotein fusion peptide of mouse hepatitis virus strongly alters neuropathology. J Biol Chem. 2019 Mar 01. PMID: 30824541.
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    9. Lee Ching C, Kenyon L, Berk M, Park C. Rheumatoid meningitis sine arthritis. J Neuroimmunol. 2019 Mar 15; 328:73-75. PMID: 30597393.
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    10. Lin R, Cai J, Kenyon L, Iozzo R, Rosenwasser R, Iacovitti L. Systemic Factors Trigger Vasculature Cells to Drive Notch Signaling and Neurogenesis in Neural Stem Cells in the Adult Brain. Stem Cells. 2018 Nov 15. PMID: 30431198.
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    11. Li Z, Curtis B, Layser R, Selvarajan SK, Harrop J, Kenyon LC, Parsons T, Rubin A. Intraosseous hemangioblastoma of the cervical spine: case report. J Neurosurg Spine. 2017 Jun 30; 1-4. PMID: 28665246.
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    12. Biswas K, Chatterjee D, Addya S, Khan RS, Kenyon LC, Choe A, Cohrs RJ, Shindler KS, Das Sarma J. Demyelinating strain of mouse hepatitis virus infection bridging innate and adaptive immune response in the induction of demyelination. Clin Immunol. 2016 Sep; 170:9-19. PMID: 27394164.
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    13. Kenyon LC, Biswas K, Shindler KS, Nabar M, Stout M, Hingley ST, Grinspan JB, Das Sarma J. Gliopathy of Demyelinating and Non-Demyelinating Strains of Mouse Hepatitis Virus. Front Cell Neurosci. 2015; 9:488. PMID: 26733813.
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    14. Sharma P, Panebra A, Pera T, Tiegs BC, Hershfeld A, Kenyon LC, Deshpande DA. Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2016 Feb 15; 310(4):L365-76. PMID: 26684251.
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    15. Harshyne LA, Nasca BJ, Kenyon LC, Andrews DW, Hooper DC. Serum exosomes and cytokines promote a T-helper cell type 2 environment in the peripheral blood of glioblastoma patients. Neuro Oncol. 2016 Feb; 18(2):206-15. PMID: 26180083.
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    16. McCormick EM, Kenyon L, Falk MJ. Desmin common mutation is associated with multi-systemic disease manifestations and depletion of mitochondria and mitochondrial DNA. Front Genet. 2015; 6:199. PMID: 26097489.
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    17. Harshyne LA, Hooper KM, Andrews EG, Nasca BJ, Kenyon LC, Andrews DW, Hooper DC. Glioblastoma exosomes and IGF-1R/AS-ODN are immunogenic stimuli in a translational research immunotherapy paradigm. Cancer Immunol Immunother. 2015 Mar; 64(3):299-309. PMID: 25391690.
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    18. Chatterjee D, Addya S, Khan RS, Kenyon LC, Choe A, Cohrs RJ, Shindler KS, Sarma JD. Mouse hepatitis virus infection upregulates genes involved in innate immune responses. PLoS One. 2014; 9(10):e111351. PMID: 25360880.
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    19. Mehta JM, Miller JL, Cannon AJ, Mardekian SK, Kenyon LC, Jabbour SA. Ovarian leydig cell hyperplasia: an unusual case of virilization in a postmenopausal woman. Case Rep Endocrinol. 2014; 2014:762745. PMID: 25045549.
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    20. Jamal SE, Li S, Bajaj R, Wang Z, Kenyon L, Glass J, Pang CS, Bhagavathi S, Peiper SC, Gong JZ. Primary central nervous system Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly: a clinicopathologic study of five cases. Brain Tumor Pathol. 2014 Oct; 31(4):265-73. PMID: 24399201.
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    21. Kishore A, Kanaujia A, Nag S, Rostami AM, Kenyon LC, Shindler KS, Das Sarma J. Different mechanisms of inflammation induced in virus and autoimmune-mediated models of multiple sclerosis in C57BL6 mice. Biomed Res Int. 2013; 2013:589048. PMID: 24083230.
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    22. Prosniak M, Harshyne LA, Andrews DW, Kenyon LC, Bedelbaeva K, Apanasovich TV, Heber-Katz E, Curtis MT, Cotzia P, Hooper DC. Glioma grade is associated with the accumulation and activity of cells bearing m2 monocyte markers. Clin Cancer Res. 2013 Jul 15; 19(14):3776-86. PMID: 23741072.
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    23. Salas SJ, McFalls JM, Senders ZJ, Kenyon LC, Harrop JS. Intradural cervical nerve root traumatic neuroma without a history of direct trauma. Clin Neurol Neurosurg. 2013 Sep; 115(9):1879-81. PMID: 23639732.
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    24. Mendoza FA, Purohit S, Kenyon L, Jimenez SA. Severe eosinophilic syndrome associated with the use of probiotic supplements: a new entity? Case Report Rheumatol. 2012; 2012:934324. PMID: 23259129.
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    25. Teufack S, Campbell P, Sharma P, Lachman T, Kenyon L, Harrop J, Prasad S. Thoracic myelopathy due to an intramedullary herniated nucleus pulposus: first case report and review of the literature. Neurosurgery. 2012 Jul; 71(1):E199-202. PMID: 22517252.
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    26. Wernicke AG, Dicker AP, Whiton M, Ivanidze J, Hyslop T, Hammond EH, Perry A, Andrews DW, Kenyon L. Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma. Radiat Oncol. 2010; 5:46. PMID: 20509969.
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    27. Yadia S, Randazzo CG, Malik S, Gressen E, Chasky M, Kenyon LC, Ratliff JK. Pilomatrix carcinoma of the thoracic spine: case report and review of the literature. J Spinal Cord Med. 2010; 33(3):272-7. PMID: 20737803.
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    28. Das Sarma J, Kenyon LC, Hingley ST, Shindler KS. Mechanisms of primary axonal damage in a viral model of multiple sclerosis. J Neurosci. 2009 Aug 19; 29(33):10272-80. PMID: 19692601.
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    29. Moulding HD, Friedman DP, Curtis M, Kenyon L, Flanders AE, Paek SH, Andrews DW. Revisiting anaplastic astrocytomas I: an expansive growth pattern is associated with a better prognosis. J Magn Reson Imaging. 2008 Dec; 28(6):1311-21. PMID: 19025897.
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    30. Buccafusca R, Venditti CP, Kenyon LC, Johanson RA, Van Bockstaele E, Ren J, Pagliardini S, Minarcik J, Golden JA, Coady MJ, Greer JJ, Berry GT. Characterization of the null murine sodium/myo-inositol cotransporter 1 (Smit1 or Slc5a3) phenotype: myo-inositol rescue is independent of expression of its cognate mitochondrial ribosomal protein subunit 6 (Mrps6) gene and of phosphatidylinositol levels in neonatal brain. Mol Genet Metab. 2008 Sep-Oct; 95(1-2):81-95. PMID: 18675571.
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    31. Singh H, Irwin S, Falowski S, Rosen M, Kenyon L, Jungkind D, Evans J. Curvularia fungi presenting as a large cranial base meningioma: case report. Neurosurgery. 2008 Jul; 63(1):E177; discussion E177. PMID: 18728558.
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    32. Shindler KS, Kenyon LC, Dutt M, Hingley ST, Das Sarma J. Experimental optic neuritis induced by a demyelinating strain of mouse hepatitis virus. J Virol. 2008 Sep; 82(17):8882-6. PMID: 18579591.
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    33. Das Sarma J, Iacono K, Gard L, Marek R, Kenyon LC, Koval M, Weiss SR. Demyelinating and nondemyelinating strains of mouse hepatitis virus differ in their neural cell tropism. J Virol. 2008 Jun; 82(11):5519-26. PMID: 18385249.
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    34. Nathwani RA, Kenyon L, Kowalski T. Rosai-Dorfman disease of the colon. Gastrointest Endosc. 2008 Jul; 68(1):194-6. PMID: 18291397.
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    35. Tang J, Flomenberg P, Harshyne L, Kenyon L, Andrews DW. Glioblastoma patients exhibit circulating tumor-specific CD8+ T cells. Clin Cancer Res. 2005 Jul 15; 11(14):5292-9. PMID: 16033848.
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    36. Fedele M, Pentimalli F, Baldassarre G, Battista S, Klein-Szanto AJ, Kenyon L, Visone R, De Martino I, Ciarmiello A, Arra C, Viglietto G, Croce CM, Fusco A. Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas. Oncogene. 2005 May 12; 24(21):3427-35. PMID: 15735694.
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    37. Mutai H, Kenyon LC, Locke E, Kikuchi N, Oberholtzer JC. Characterization of the chicken inward rectifier K+ channel IRK1/Kir2.1 gene. BMC Genomics. 2004 Nov 29; 5:90. PMID: 15569391.
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    38. Behling E, Birbe R, Veznadaroglu E, Andrews DW, Flanders A, Kenyon LC. Gliosarcoma arising from an anaplastic ependymoma: a case report of a rare entity. Hum Pathol. 2004 Apr; 35(4):512-6. PMID: 15116335.
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    39. Bloomer CW, Kenyon L, Hammond E, Hyslop T, Andrews DW, Curran WJ, Dicker AP. Cyclooxygenase-2 (COX-2) and epidermal growth factor receptor (EGFR) expression in human pituitary macroadenomas. Am J Clin Oncol. 2003 Aug; 26(4):S75-80. PMID: 12902861.
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    40. Lin CC, Kenyon L, Hyslop T, Hammond E, Andrews DW, Curran WJ, Dicker AP. Cyclooxygenase-2 (COX-2) expression in human meningioma as a function of tumor grade. Am J Clin Oncol. 2003 Aug; 26(4):S98-102. PMID: 12902865.
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    41. Tsuiki H, Tnani M, Okamoto I, Kenyon LC, Emlet DR, Holgado-Madruga M, Lanham IS, Joynes CJ, Vo KT, Wong AJ. Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors. Cancer Res. 2003 Jan 1; 63(1):250-5. PMID: 12517805.
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    42. Okamoto I, Kenyon LC, Emlet DR, Mori T, Sasaki J, Hirosako S, Ichikawa Y, Kishi H, Godwin AK, Yoshioka M, Suga M, Matsumoto M, Wong AJ. Expression of constitutively activated EGFRvIII in non-small cell lung cancer. Cancer Sci. 2003 Jan; 94(1):50-6. PMID: 12708474.
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    43. Friedman O, Neff BA, Willcox TO, Kenyon LC, Sataloff RT. Temporal bone hemangiomas involving the facial nerve. Otol Neurotol. 2002 Sep; 23(5):760-6. PMID: 12218631.
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    44. Antonyak MA, Kenyon LC, Godwin AK, James DC, Emlet DR, Okamoto I, Tnani M, Holgado-Madruga M, Moscatello DK, Wong AJ. Elevated JNK activation contributes to the pathogenesis of human brain tumors. Oncogene. 2002 Aug 1; 21(33):5038-46. PMID: 12140754.
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    45. Fedele M, Battista S, Kenyon L, Baldassarre G, Fidanza V, Klein-Szanto AJ, Parlow AF, Visone R, Pierantoni GM, Outwater E, Santoro M, Croce CM, Fusco A. Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas. Oncogene. 2002 May 9; 21(20):3190-8. PMID: 12082634.
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    46. Okamoto I, Tsuiki H, Kenyon LC, Godwin AK, Emlet DR, Holgado-Madruga M, Lanham IS, Joynes CJ, Vo KT, Guha A, Matsumoto M, Ushio Y, Saya H, Wong AJ. Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors. Am J Pathol. 2002 Feb; 160(2):441-7. PMID: 11839564.
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    47. Agha B, Rasheed M, Kenyon L, Jimenez SA. Hepatitis C virus infection, inflammatory myopathy, and pulmonary fibrosis: are they related? J Clin Rheumatol. 2002 Feb; 8(1):44-9. PMID: 17039200.
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