Thomas Jefferson University

Michael Sperling

TitleFaculty Physician
InstitutionThomas Jefferson University
DepartmentNeurology - Thomas Jefferson University
Address900 Walnut Street
Philadelphia PA 19107
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    HOSPITAL APPOINTMENTS
    Graduate Hospital, Philadelphia, PA
    Director, Neurophysiology Laboratory, 1985 - 1997
    Director, Epilepsy Monitoring Unit 1985 - 1997
    Director, Comprehensive Epilepsy Center, 1995- 1997
    Thomas Jefferson University Hospital, Philadelphia, PA
    Director, Jefferson Comprehensive Epilepsy Center, 1997 - present
    Director, Clinical Neurophysiology Laboratory, 1997 - present

    PROFESSIONAL ACTIVITIES

    1999-2000 President of American Clinical Neurophysiology Society
    2002-2003 President of Philadelphia Neurological Society
    Fellow, American Academy of Neurology
    Member, American Neurological Association
    Member, American Epilepsy Society
    Member, American Clinical Neurophysiology Society

    EDUCATIONAL

    Director of Fellowship Program in Epilepsy and Clinical Neurophysiology, Thomas Jefferson University Hospital
    Medical student and resident lectures and teaching
    Weekly morning report

    CLINICAL
    1. Developed epilepsy program at the Graduate Hospital, including design and development of the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), contributing to development of experimental antiepileptic drug program, and clinical research program.
    2. Developed the Comprehensive Epilepsy Center at Thomas Jefferson University, including designing and developing the epilepsy monitoring unit and EEG laboratory, epilepsy surgical program (with Dr. Michael O'Connor), experimental antiepileptic drug program, and clinical research program.
    3. Developed intraoperative brain mapping program at Thomas Jefferson University Hospital


    EDITORIAL POSITIONS
    Associate Editor: Epilepsia 2007 - present
    Member, Editorial Board: Journal of Epilepsy, 1991-1999, Epilepsy Advances, 1993-95, 1996-1998, Epilepsy Research, 1999-2007.

    Reviewer: Electroencephalography and Clinical Neurophysiology, Annals of Neurology, Neurology, Epilepsia, Journal of Clinical Neurophysiology, Neuroradiology, Journal of Neurological Sciences, Archives of Neurology, JAMA, New England Journal of Medicine, Lancet




    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dimakopoulos V, Gotman J, Klimes P, von Ellenrieder N, Tan SB, Smith G, Gliske SV, Maltseva M, Manalo MK, Pail M, Brazdil M, van Blooijs D, van 't Klooster MA, Johnson S, Laboy S, Ledergerber D, Imbach L, Papadelis C, Sperling MR, Zijlmans M, Cimbalnik J, Jacobs J, Stacey WC, Frauscher B, Sarnthein J. Multicentre analysis of seizure outcome predicted by removal of high-frequency oscillations. Brain. 2025 May 13; 148(5):1769-1777. PMID: 39530262.
      Citations:    
    2. Dave H, McCreary M, Guerra A, Sperling MR. Factors influencing seizure induction in patients with intracranial EEG recording. Epilepsia. 2025 Jun; 66(6):2089-2098. PMID: 40019472.
      Citations:    
    3. Loushy I, Goldstein L, Devlin K, Volski A, Fletman E, Alcala-Zermeno JL, Porreca L, Sperling MR. Real-world use of cenobamate in adults: Efficacy and predictors of treatment response. Epilepsia. 2025 May; 66(5):1492-1504. PMID: 39932255.
      Citations:    
    4. Lin K, Eyal S, Demarchi IG, Ben-Shushan T, Auvin S, Khoo CS, Al-Baradie R, Sen A, Newton C, Ngwende GW, Candez NM, Sperling M, Brigo F, Jette N, Wiebe S. Prioritizing questions and topics for the development of guidelines and consensus-based recommendations supported by ILAE: A scoping review and proposal of prioritization criteria. Epilepsia. 2025 May; 66(5):1406-1416. PMID: 39878760.
      Citations:    
    5. Myers P, Gunnarsdottir KM, Li A, Razskazovskiy V, Craley J, Chandler A, Wyeth D, Wyeth E, Zaghloul KA, Inati SK, Hopp JL, Haridas B, Gonzalez-Martinez J, Bag?c A, Kang JY, Sperling MR, Barot N, Sarma SV, Husari KS. Diagnosing Epilepsy with Normal Interictal EEG Using Dynamic Network Models. Ann Neurol. 2025 05; 97(5):907-918. PMID: 39817338.
      Citations:    
    6. Alcala-Zermeno JL, Romozzi M, Sperling MR. The effect of epilepsy surgery on tonic-clonic seizures. Epilepsia. 2025 Apr; 66(4):1048-1058. PMID: 39754525.
      Citations:    
    7. Weiss SA, Sperling MR, Engel J, Liu A, Fried I, Wu C, Doyle W, Mikell C, Mofakham S, Salamon N, Sim MS, Bragin A, Staba R. Simulated resections and responsive neurostimulator placement can optimize postoperative seizure outcomes when guided by fast ripple networks. Brain Commun. 2024; 6(5):fcae367. PMID: 39464217.
      Citations:    
    8. Zhang Q, Hudgins S, Struck AF, Ankeeta A, Javidi SS, Sperling MR, Hermann BP, Tracy JI. Association of Normative and Non-Normative Brain Networks With Cognitive Function in Patients With Temporal Lobe Epilepsy. Neurology. 2024 Oct 08; 103(7):e209800. PMID: 39250744.
      Citations:    
    9. Gill S, Devlin KN, Yuan H, Mintzer S, Skidmore C, Wu C, Sperling MR, Nei M. Long-Term Seizure Outcome With or Without Vagal Nerve Stimulation Therapy. Neurol Clin Pract. 2024 Dec; 14(6):e200358. PMID: 39185099.
      Citations:    
    10. Weiss SA, Sperling MR, Engel J, Staba R. To plan efficacious epilepsy surgery. Brain. 2024 Aug 01; 147(8):e55-e57. PMID: 38758083.
      Citations:    
    11. Sperling MR. Farewell from the Editor-in-Chief. Epilepsia. 2024 Aug; 65(8):2183-2184. PMID: 39082246.
      Citations:    
    12. Sawczuk N, Rubinstein DY, Sperling MR, Wendel-Mitoraj K, Djuric P, Slezak DF, Kamienkowski J, Weiss SA. High-gamma and beta bursts in the Left Supramarginal Gyrus can accurately differentiate verbal memory states and performance. medRxiv. 2024 Jun 28. PMID: 38853875.
      Citations:    
    13. Sperling MR. An interview with Marwa Elamin, 2024 Epilepsia prize winner for basic science research. Epilepsia. 2024 Aug; 65(8):2499-2500. PMID: 38881435.
      Citations:    
    14. Sperling MR. An interview with Benjamin D. Wissel, 2024 Epilepsia Prize winner for clinical research. Epilepsia. 2024 Aug; 65(8):2497-2498. PMID: 38881425.
      Citations:    
    15. Javidi SS, He X, Ankeeta A, Zhang Q, Citro S, Sperling MR, Tracy JI. Edge-wise analysis reveals white matter connectivity associated with focal to bilateral tonic-clonic seizures. Epilepsia. 2024 Jun; 65(6):1756-1767. PMID: 38517477.
      Citations:    
    16. Wang Z, Sperling MR, Wyeth D, Guez A. Automated Seizure Detection Based on State-Space Model Identification. Sensors (Basel). 2024 Mar 16; 24(6). PMID: 38544166.
      Citations:    
    17. Sathe AV, Alizadeh M, Johannan E, Raimondo C, Sperling M, Sharan A, Kogan M. Stereotactic Electroencephalogram Recordings in Temporal Lobectomy Patients Demonstrates the Predictive Value of Interictal Cross-Frequency Correlations: A Retrospective Study. Brain Sci. 2024 Feb 26; 14(3). PMID: 38539601.
      Citations:    
    18. Perucca E, French JA, Aljandeel G, Balestrini S, Braga P, Burneo JG, Felli AC, Cross JH, Galanopoulou AS, Jain S, Jiang Y, K?lvi?inen R, Lim SH, Meador KJ, Mogal Z, Nabbout R, Sofia F, Somerville E, Sperling MR, Triki C, Trinka E, Walker MC, Wiebe S, Wilmshurst JM, Wirrell E, Yacubian EM, Kapur J. Which terms should be used to describe medications used in the treatment of seizure disorders? An ILAE position paper. Epilepsia. 2024 Mar; 65(3):533-541. PMID: 38279786.
      Citations:    
    19. Ezzyat Y, Kragel JE, Solomon EA, Lega BC, Aronson JP, Jobst BC, Gross RE, Sperling MR, Worrell GA, Sheth SA, Wanda PA, Rizzuto DS, Kahana MJ. Functional and anatomical connectivity predict brain stimulation's mnemonic effects. Cereb Cortex. 2024 01 14; 34(1). PMID: 38041253.
      Citations:    
    20. Misra SN, Sperling MR, Rao VR, Peters JM, Penovich P, Wheless J, Hogan RE, Davis CS, Carrazana E, Rabinowicz AL. Analyses of patients who self-administered diazepam nasal spray for acute treatment of seizure clusters. Epilepsy Behav Rep. 2024; 25:100644. PMID: 38274142.
      Citations:    
    21. Hadady L, Sperling MR, Alcala-Zermeno JL, French JA, Dugan P, Jehi L, Fab? D, Kliv?nyi P, Rubboli G, Beniczky S. Prediction tools and risk stratification in epilepsy surgery. Epilepsia. 2024 Feb; 65(2):414-421. PMID: 38060351.
      Citations:    
    22. Weiss SA, Fried I, Engel J, Bragin A, Wang S, Sperling MR, Wong RKS, Nir Y, Staba RJ. Pathological neurons generate ripples at the UP-DOWN transition disrupting information transfer. Epilepsia. 2024 02; 65(2):362-377. PMID: 38041560.
      Citations:    
    23. Sperling MR, Wu C, Kang J, Makhalova J, Bartolomei F, Southwell D. The Temporal Lobe Club: Newer Approaches to Treat Temporal Lobe Epilepsy. Epilepsy Curr. 2024 Jan-Feb; 24(1):10-15. PMID: 38327532.
      Citations:    
    24. Richter H, Verlemann C, Jeibmann A, Martin LF, Luebke AM, Karol A, Sperling M, Radbruch A, Karst U. Elemental Bioimaging of Sheep Bone and Articular Cartilage After Single Application of Gadolinium-Based Contrast Agents. Invest Radiol. 2024 04 01; 59(4):287-292. PMID: 37747456.
      Citations:    
    25. Weiss SA, Fried I, Engel J, Sperling MR, Wong RKS, Nir Y, Staba RJ. Fast ripples reflect increased excitability that primes epileptiform spikes. Brain Commun. 2023; 5(5):fcad242. PMID: 37869578.
      Citations:    
    26. Wilmshurst JM, Sperling MR. Equity in access to antiseizure medications: Who has the right to decide and what are the consequences of crisis decisions? Epilepsia. 2023 08; 64(8):2011-2013. PMID: 37326490.
      Citations:    
    27. Youngerman BE, Banu MA, Khan F, McKhann GM, Schevon CA, Jagid JR, Cajigas I, Theodotou CB, Ko A, Buckley R, Ojemann JG, Miller JW, Laxton AW, Couture DE, Popli GS, Buch VP, Halpern CH, Le S, Sharan AD, Sperling MR, Mehta AD, Englot DJ, Neimat JS, Konrad PE, Sheth SA, Neal EG, Vale FL, Holloway KL, Air EL, Schwalb JM, D'Haese PF, Wu C. Long-term outcomes of mesial temporal laser interstitial thermal therapy for drug-resistant epilepsy and subsequent surgery for seizure recurrence: a multi-centre cohort study. J Neurol Neurosurg Psychiatry. 2023 11; 94(11):879-886. PMID: 37336643.
      Citations:    
    28. Rosenfeld WE, Ferrari L, Kerr WT, Sperling MR. Sudden unexpected death in epilepsy during cenobamate clinical development. Epilepsia. 2023 08; 64(8):2108-2115. PMID: 37219391.
      Citations:    
    29. Sperling MR. An interview with Brad Kamitaki, 2023 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2023 08; 64(8):2212-2213. PMID: 37195246.
      Citations:    
    30. Sperling MR. An interview with Riccardo De Feo, 2023 Epilepsia Prize winner for Basic Science Research. Epilepsia. 2023 08; 64(8):2214-2215. PMID: 37195247.
      Citations:    
    31. Rubinstein DY, Weidemann CT, Sperling MR, Kahana MJ. Direct brain recordings suggest a causal subsequent-memory effect. Cereb Cortex. 2023 05 24; 33(11):6891-6901. PMID: 36702495.
      Citations:    
    32. Richter H, Koke A, Soschinski PN, Martin LF, B?cker P, Sperling M, Karst U, Radbruch A, Witten A, Jeibmann A. Elemental bioimaging and transcriptomics reveal unchanged gene expression in mouse cerebellum following a single injection of Gadolinium-based contrast agents. Sci Rep. 2023 04 26; 13(1):6844. PMID: 37100846.
      Citations:    
    33. Weiss SA, Fried I, Engel J, Sperling MR, Wong RKS, Nir Y, Staba RJ. Fast ripples reflect increased excitability that primes epileptiform spikes. medRxiv. 2023 Apr 19. PMID: 37034609.
      Citations:    
    34. Rehman M, Higdon LM, Sperling MR. Long-Term Home EEG Recording: Wearable and Implantable Devices. J Clin Neurophysiol. 2024 Mar 01; 41(3):200-206. PMID: 38436387.
      Citations:    
    35. Klein P, Krauss GL, Steinhoff BJ, Devinsky O, Sperling MR. Failure to use new breakthrough treatments for epilepsy. Epilepsia. 2023 06; 64(6):1458-1465. PMID: 36855241.
      Citations:    
    36. Herweg NA, Kunz L, Schonhaut D, Brandt A, Wanda PA, Sharan AD, Sperling MR, Schulze-Bonhage A, Kahana MJ. A Learned Map for Places and Concepts in the Human Medial Temporal Lobe. J Neurosci. 2023 05 10; 43(19):3538-3547. PMID: 37001991.
      Citations:    
    37. Hinds W, Modi S, Ankeeta A, Sperling MR, Pustina D, Tracy JI. Pre-surgical features of intrinsic brain networks predict single and joint epilepsy surgery outcomes. Neuroimage Clin. 2023; 38:103387. PMID: 37023491.
      Citations:    
    38. Weiss SA, Eliashiv D, Stern J, Rubinstein D, Fried I, Wu C, Sharan A, Engel J, Staba R, Sperling MR. Stimulation better targets fast-ripple generating networks in super responders to the responsive neurostimulator system. Epilepsia. 2023 05; 64(5):e48-e55. PMID: 36906958.
      Citations:    
    39. Weiss SA, Fried I, Wu C, Sharan A, Rubinstein D, Engel J, Sperling MR, Staba RJ. Graph theoretical measures of fast ripple networks improve the accuracy of post-operative seizure outcome prediction. Sci Rep. 2023 01 07; 13(1):367. PMID: 36611059.
      Citations:    
    40. Kanner AM, Saporta AS, Kim DH, Barry JJ, Altalib H, Omotola H, Jette N, O'Brien TJ, Nadkarni S, Winawer MR, Sperling M, French JA, Abou-Khalil B, Alldredge B, Bebin M, Cascino GD, Cole AJ, Cook MJ, Detyniecki K, Devinsky O, Dlugos D, Faught E, Ficker D, Fields M, Gidal B, Gelfand M, Glynn S, Halford JJ, Haut S, Hegde M, Holmes MG, Kalviainen R, Kang J, Klein P, Knowlton RC, Krishnamurthy K, Kuzniecky R, Kwan P, Lowenstein DH, Marcuse L, Meador KJ, Mintzer S, Pardoe HR, Park K, Penovich P, Singh RK, Somerville E, Szabo CA, Szaflarski JP, Lin Thio KL, Trinka E, Burneo JG. Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity. Neurology. 2023 03 14; 100(11):e1123-e1134. PMID: 36539302.
      Citations:    
    41. Perucca P, Stanley K, Harris N, McIntosh AM, Asadi-Pooya AA, Mikati MA, Andrade DM, Dugan P, Depondt C, Choi H, Heinzen EL, Cavalleri GL, Buono RJ, Devinsky O, Sperling MR, Berkovic SF, Delanty N, Goldstein DB, O'Brien TJ. Rare Genetic Variation and Outcome of Surgery for Mesial Temporal Lobe Epilepsy. Ann Neurol. 2022 Dec 19. PMID: 36534060.
      Citations:    
    42. Weiss SA, Sheybani L, Seenarine N, Fried I, Wu C, Sharan A, Engel J, Sperling MR, Nir Y, Staba RJ. Delta oscillation coupled propagating fast ripples precede epileptiform discharges in patients with focal epilepsy. Neurobiol Dis. 2022 12; 175:105928. PMID: 36403895.
      Citations:    
    43. He X, Caciagli L, Parkes L, Stiso J, Karrer TM, Kim JZ, Lu Z, Menara T, Pasqualetti F, Sperling MR, Tracy JI, Bassett DS. Uncovering the biological basis of control energy: Structural and metabolic correlates of energy inefficiency in temporal lobe epilepsy. Sci Adv. 2022 Nov 11; 8(45):eabn2293. PMID: 36351015.
      Citations:    
    44. Funke SKI, Factor C, Rasschaert M, Robert P, van Dijk NWM, Hu?ock M, Sperling M, Karst U. Elemental Imaging of Long-term Gadolinium Retention in Rodent Femur. Radiology. 2023 Feb; 306(2):e213107. PMID: 36194115.
      Citations:    
    45. Nascimento FA, Jing J, Strowd R, Sheikh IS, Weber D, Gavvala JR, Maheshwari A, Tanner A, Ng M, Vinayan KP, Sinha SR, Yacubian EM, Rao VR, Perry MS, Fountain NB, Karakis I, Wirrell E, Yuan F, Friedman D, Tankisi H, Rampp S, Fasano R, Wilmshurst JM, O'Donovan C, Schomer D, Kaplan PW, Sperling MR, Benbadis S, Westover MB, Beniczky S. Competency-based EEG education: a list of "must-know" EEG findings for adult and child neurology residents Epileptic Disord. 2022 10 01; 24(5):979-982. PMID: 35904042.
      Citations:    
    46. Angus-Leppan H, Sperling MR, Villanueva V. Antiseizure medications (antiepileptic drugs) in adults: starting, monitoring and stopping. J Neurol. 2023 Jan; 270(1):573-581. PMID: 36153467.
      Citations:    
    47. Wheless JW, Friedman D, Krauss GL, Rao VR, Sperling MR, Carrazana E, Rabinowicz AL. Future opportunities for research in rescue treatments. Epilepsia. 2022 09; 63 Suppl 1:S55-S68. PMID: 35822912.
      Citations:    
    48. Sperling MR. From the Editor-in-Chief. Epilepsia. 2022 Sep; 63(9):2171. PMID: 35979604.
      Citations:    
    49. Misra SN, Sperling MR, Rao VR, Peters JM, Davis C, Carrazana E, Rabinowicz AL. Significant improvements in SEIzure interVAL (time between seizure clusters) across time in patients treated with diazepam nasal spray as intermittent rescue therapy for seizure clusters. Epilepsia. 2022 10; 63(10):2684-2693. PMID: 35975599.
      Citations:    
    50. Simpson HD, Schulze-Bonhage A, Cascino GD, Fisher RS, Jobst BC, Sperling MR, Lundstrom BN. Practical considerations in epilepsy neurostimulation. Epilepsia. 2022 10; 63(10):2445-2460. PMID: 35700144.
      Citations:    
    51. Jehi L, Jette N, Kwon CS, Josephson CB, Burneo JG, Cendes F, Sperling MR, Baxendale S, Busch RM, Triki CC, Cross JH, Ekstein D, Englot DJ, Luan G, Palmini A, Rios L, Wang X, Roessler K, Rydenhag B, Ramantani G, Schuele S, Wilmshurst JM, Wilson S, Wiebe S. Timing of referral to evaluate for epilepsy surgery: Expert Consensus Recommendations from the Surgical Therapies Commission of the International League Against Epilepsy. Epilepsia. 2022 10; 63(10):2491-2506. PMID: 35842919.
      Citations:    
    52. Camarillo-Rodriguez L, Leenen I, Waldman Z, Serruya M, Wanda PA, Herweg NA, Kahana MJ, Rubinstein D, Orosz I, Lega B, Podkorytova I, Gross RE, Worrell G, Davis KA, Jobst BC, Sheth SA, Weiss SA, Sperling MR. Temporal lobe interictal spikes disrupt encoding and retrieval of verbal memory: A subregion analysis. Epilepsia. 2022 09; 63(9):2325-2337. PMID: 35708911.
      Citations:    
    53. Funke SKI, Factor C, Rasschaert M, Lezius L, Sperling M, Karst U, Robert P. Long-term Gadolinium Retention in the Healthy Rat Brain: Comparison between Gadopiclenol, Gadobutrol, and Gadodiamide. Radiology. 2022 10; 305(1):179-189. PMID: 35727155.
      Citations:    
    54. Dimakopoulos V, Gotman J, Stacey W, von Ellenrieder N, Jacobs J, Papadelis C, Cimbalnik J, Worrell G, Sperling MR, Zijlmans M, Imbach L, Frauscher B, Sarnthein J. Protocol for multicentre comparison of interictal high-frequency oscillations as a predictor of seizure freedom. Brain Commun. 2022; 4(3):fcac151. PMID: 35770134.
      Citations:    
    55. Abou-Khalil B, Aboumatar S, Klein P, Krauss GL, Sperling MR, Rosenfeld WE. Efficacy of cenobamate for uncontrolled focal seizures in patients with previous epilepsy-related surgery: Post hoc analysis of a phase 3, multicenter, open-label study. Epilepsy Res. 2022 08; 184:106952. PMID: 35671632.
      Citations:    
    56. Nehlig A, Sperling MR. The debate on the treatment of neonatal seizures: Introductory remarks. Epilepsia. 2022 07; 63(7):1862. PMID: 35524449.
      Citations:    
    57. Hirsch E, French J, Scheffer IE, Bogacz A, Alsaadi T, Sperling MR, Abdulla F, Zuberi SM, Trinka E, Specchio N, Somerville E, Samia P, Riney K, Nabbout R, Jain S, Wilmshurst JM, Auvin S, Wiebe S, Perucca E, Mosh? SL, Tinuper P, Wirrell EC. ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions. Epilepsia. 2022 06; 63(6):1475-1499. PMID: 35503716.
      Citations:    
    58. Weiss SA, Pastore T, Orosz I, Rubinstein D, Gorniak R, Waldman Z, Fried I, Wu C, Sharan A, Slezak D, Worrell G, Engel J, Sperling MR, Staba RJ. Graph theoretical measures of fast ripples support the epileptic network hypothesis. Brain Commun. 2022; 4(3):fcac101. PMID: 35620169.
      Citations:    
    59. Cascino GD, Tarquinio D, Wheless JW, Hogan RE, Sperling MR, Desai J, Vazquez B, Samara E, Misra SN, Carrazana E, Rabinowicz AL. Lack of clinically relevant differences in safety and pharmacokinetics after second-dose administration of intranasal diazepam within 4?h for acute treatment of seizure clusters: A population analysis. Epilepsia. 2022 07; 63(7):1714-1723. PMID: 35377464.
      Citations:    
    60. Nehlig A, Sperling MR. An interview with Margherita Contento, 2022 Epilepsia Prize winner for clinical research. Epilepsia. 2022 05; 63(5):1021-1022. PMID: 35315063.
      Citations:    
    61. Nehlig A, Sperling MR. An interview with Carmen De Caro, 2022 Epilepsia Prize?Winner for Basic Science. Epilepsia. 2022 05; 63(5):1023-1024. PMID: 35315134.
      Citations:    
    62. Klodowski DA, George BJ, Sperling MR. Seizure latency and epilepsy localization as predictors of recurrence following epilepsy surgery. Epilepsia. 2022 05; 63(5):1074-1080. PMID: 35286721.
      Citations:    
    63. Isaac E, Ney D, Serruya M, Keith S, Lippa C, Sperling MR. Tolerability of memantine monotherapy versus adding memantine as combination therapy. J Natl Med Assoc. 2022 Jun; 114(3):308-313. PMID: 35272847.
      Citations:    
    64. Klein P, McCarter R, Sperling MR. Comments on the Evaluation of Suicidality Risk of Newer Antiseizure Medications-Reply. JAMA Neurol. 2022 03 01; 79(3):310-311. PMID: 35099505.
      Citations:    
    65. Sperling MR, Wheless JW, Hogan RE, Dlugos D, Cascino GD, Liow K, Rabinowicz AL, Carrazana E. Use of second doses of Valtoco? (diazepam nasal spray) across 24?hours after the initial dose for out-of-hospital seizure clusters: Results from a phase 3, open-label, repeat-dose safety study. Epilepsia. 2022 04; 63(4):836-843. PMID: 35112342.
      Citations:    
    66. Steriade C, Sperling MR, DiVentura B, Lozano M, Shellhaas RA, Kessler SK, Dlugos D, French J. Proposal for an updated seizure classification framework in clinical trials. Epilepsia. 2022 03; 63(3):565-572. PMID: 34997581.
      Citations:    
    67. Begasse De Dhaem O, Aldana SI, Kanner AM, Sperling M, French J, Nadkarni SS, Hope OA, O'Brien T, Morrison C, Winawer M, Minen MT. Association Between Migraine Comorbidity and Psychiatric Symptoms Among People With Newly Diagnosed Focal Epilepsy. J Neuropsychiatry Clin Neurosci. 2022; 34(2):182-187. PMID: 34961330.
      Citations:    
    68. Hadady L, Kliv?nyi P, Perucca E, Rampp S, Fab? D, Bereczki C, Rubboli G, Asadi-Pooya AA, Sperling MR, Beniczky S. Web-based decision support system for patient-tailored selection of antiseizure medication in adolescents and adults: An external validation study. Eur J Neurol. 2022 02; 29(2):382-389. PMID: 34741372.
      Citations:    
    69. Asadi-Pooya AA, Beniczky S, Rubboli G, Sperling MR, Rampp S, Perucca E. The EpiPick algorithm to select appropriate antiseizure medications in patients with epilepsy: Validation studies and updates. Epilepsia. 2022 01; 63(1):254-255. PMID: 34797915.
      Citations:    
    70. Weiss SA, Staba RJ, Sharan A, Wu C, Rubinstein D, Das S, Waldman Z, Orosz I, Worrell G, Engel J, Sperling MR. Accuracy of high-frequency oscillations recorded intraoperatively for classification of epileptogenic regions. Sci Rep. 2021 11 01; 11(1):21388. PMID: 34725412.
      Citations:    
    71. Modi S, He X, Chaudhary K, Hinds W, Crow A, Beloor-Suresh A, Sperling MR, Tracy JI. Multiple-brain systems dynamically interact during tonic and phasic states to support language integrity in temporal lobe epilepsy. Neuroimage Clin. 2021; 32:102861. PMID: 34688143.
      Citations:    
    72. Rosenfeld WE, Abou-Khalil B, Aboumatar S, Bhatia P, Biton V, Krauss GL, Sperling MR, Vossler DG, Klein P, Wechsler R. Post hoc analysis of a phase 3, multicenter, open-label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications. Epilepsia. 2021 12; 62(12):3016-3028. PMID: 34633074.
      Citations:    
    73. Sperling MR, Abou-Khalil B, Aboumatar S, Bhatia P, Biton V, Klein P, Krauss GL, Vossler DG, Wechsler R, Ferrari L, Grall M, Rosenfeld WE. Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open-label study. Epilepsia. 2021 12; 62(12):3005-3015. PMID: 34633084.
      Citations:    
    74. Richter H, B?cker P, Martin LF, Dunker C, Fingerhut S, Xia A, Karol A, Sperling M, Karst U, Radbruch A, Jeibmann A. Gadolinium Tissue Distribution in a Large-Animal Model after a Single Dose of Gadolinium-based Contrast Agents. Radiology. 2021 12; 301(3):637-642. PMID: 34546128.
      Citations:    
    75. Tarighati Rasekhi R, Devlin KN, Sperling MR, Nei M. Response: SUDEP-7 Inventory: Validation in a retrospective cohort study. Epilepsia. 2021 11; 62(11):2873-2874. PMID: 34545575.
      Citations:    
    76. Buono RJ, Bradfield JP, Wei Z, Sperling MR, Dlugos DJ, Privitera MD, French JA, Lo W, Cossette P, Schachter SC, Basehore H, Lohoff FW, Grant SFA, Ferraro TN, Hakonarson H. Genetic Variation in PADI6-PADI4 on 1p36.13 Is Associated with Common Forms of Human Generalized Epilepsy. Genes (Basel). 2021 09 18; 12(9). PMID: 34573423.
      Citations:    
    77. Quon RJ, Camp EJ, Meisenhelter S, Song Y, Steimel SA, Testorf ME, Andrew AS, Gross RE, Lega BC, Sperling MR, Kahana MJ, Jobst BC. Features of intracranial interictal epileptiform discharges associated with memory encoding. Epilepsia. 2021 11; 62(11):2615-2626. PMID: 34486107.
      Citations:    
    78. Klein P, Devinsky O, French J, Harden C, Krauss GL, McCarter R, Sperling MR. Suicidality Risk of Newer Antiseizure Medications: A Meta-analysis. JAMA Neurol. 2021 09 01; 78(9):1118-1127. PMID: 34338718.
      Citations:    
    79. Beniczky S, Asadi-Pooya AA, Perucca E, Rubboli G, Tartara E, Meritam Larsen P, Ebrahimi S, Farzinmehr S, Rampp S, Sperling MR. A web-based algorithm to rapidly classify seizures for the purpose of drug selection. Epilepsia. 2021 10; 62(10):2474-2484. PMID: 34420206.
      Citations:    
    80. Solomon EA, Sperling MR, Sharan AD, Wanda PA, Levy DF, Lyalenko A, Pedisich I, Rizzuto DS, Kahana MJ. Theta-burst stimulation entrains frequency-specific oscillatory responses. Brain Stimul. 2021 Sep-Oct; 14(5):1271-1284. PMID: 34428553.
      Citations:    
    81. Wheless JW, Miller I, Hogan RE, Dlugos D, Biton V, Cascino GD, Sperling MR, Liow K, Vazquez B, Segal EB, Tarquinio D, Mauney W, Desai J, Rabinowicz AL, Carrazana E. Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy. Epilepsia. 2021 10; 62(10):2485-2495. PMID: 34418086.
      Citations:    
    82. Bjellvi J, Cross JH, Gogou M, Leclercq M, Rheims S, Ryvlin P, Sperling MR, Rydenhag B, Malmgren K. Classification of complications of epilepsy surgery and invasive diagnostic procedures: A proposed protocol and feasibility study. Epilepsia. 2021 11; 62(11):2685-2696. PMID: 34405890.
      Citations:    
    83. Higdon LM, Sperling MR. A review of a diazepam nasal spray for the treatment of acute seizure clusters and prolonged seizures. Expert Rev Neurother. 2021 11; 21(11):1207-1212. PMID: 34374629.
      Citations:    
    84. Gross RE, Fisher RS, Sperling MR, Giftakis JE, Stypulkowski PH. Analysis of Deep Brain Stimulation Lead Targeting in the Stimulation of Anterior Nucleus of the Thalamus for Epilepsy Clinical Trial. Neurosurgery. 2021 08 16; 89(3):406-412. PMID: 34161589.
      Citations:    
    85. Kang JY, Yenokyan G, Sperling MR, Nei M. Response: "Low statistical power in a study predicting seizure outcome". Epilepsia. 2021 10; 62(10):2567. PMID: 34350989.
      Citations:    
    86. Kragel JE, Ezzyat Y, Lega BC, Sperling MR, Worrell GA, Gross RE, Jobst BC, Sheth SA, Zaghloul KA, Stein JM, Kahana MJ. Distinct cortical systems reinstate the content and context of episodic memories. Nat Commun. 2021 07 21; 12(1):4444. PMID: 34290240.
      Citations:    
    87. Kandregula S, Matias CM, Malla BR, Sperling MR, Wu C, Sharan AD. Accuracy of Electrode Insertion Using Frame-Based With Robot Guidance Technique in Stereotactic Electroencephalography: Supine Versus Lateral Position. World Neurosurg. 2021 10; 154:e325-e332. PMID: 34284161.
      Citations:    
    88. French JA, Chung SS, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Kamin M. Long-term safety of adjunctive cenobamate in patients with uncontrolled focal seizures: Open-label extension of a randomized clinical study. Epilepsia. 2021 09; 62(9):2142-2150. PMID: 34254673.
      Citations:    
    89. Nehlig A, Sperling MR. An interview with Shruthi Iyer, 2021 Epilepsia Prize Winner for Basic Science Research. Epilepsia. 2021 08; 62(8):1761-1762. PMID: 34231915.
      Citations:    
    90. Sperling MR, Nehlig A. An interview with Christian Meisel, 2021 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2021 08; 62(8):1763-1764. PMID: 34231879.
      Citations:    
    91. Velagapudi L, Matias CM, Ambrose TM, Sperling MR, Nei M, Wu C, Sharan AD. Alternate Seizure Spread with Agenesis of the Corpus Callosum. J Epilepsy Res. 2021 Jun; 11(1):100-105. PMID: 34395230.
      Citations:    
    92. Tarighati Rasekhi R, Devlin KN, Mass JA, Donmez M, Asma B, Sperling MR, Nei M. Improving prediction of sudden unexpected death in epilepsy: From SUDEP-7 to SUDEP-3. Epilepsia. 2021 07; 62(7):1536-1545. PMID: 34086290.
      Citations:    
    93. Miller I, Wheless JW, Hogan RE, Dlugos D, Biton V, Cascino GD, Sperling MR, Liow K, Vazquez B, Segal EB, Tarquinio D, Mauney W, Desai J, Rabinowicz AL, Carrazana E. Consistent safety and tolerability of Valtoco? (diazepam nasal spray) in relationship to usage frequency in patients with seizure clusters: Interim results from a phase 3, long-term, open-label, repeat-dose safety study. Epilepsia Open. 2021 09; 6(3):504-512. PMID: 34033266.
      Citations:    
    94. Segal EB, Tarquinio D, Miller I, Wheless JW, Dlugos D, Biton V, Cascino GD, Desai J, Hogan RE, Liow K, Sperling MR, Vazquez B, Cook DF, Rabinowicz AL, Carrazana E. Evaluation of diazepam nasal spray in patients with epilepsy concomitantly using maintenance benzodiazepines: An interim subgroup analysis from a phase 3, long-term, open-label safety study. Epilepsia. 2021 06; 62(6):1442-1450. PMID: 33942315.
      Citations:    
    95. Cascino GD, Tarquinio D, Wheless JW, Hogan RE, Sperling MR, Liow K, Desai J, Davis C, Rabinowicz AL, Carrazana E. Lack of observed tolerance to diazepam nasal spray (Valtoco?) after long-term rescue therapy in patients with epilepsy: Interim results from a phase 3, open-label, repeat-dose safety study. Epilepsy Behav. 2021 07; 120:107983. PMID: 33957437.
      Citations:    
    96. Tantawi M, Miao J, Matias C, Skidmore CT, Sperling MR, Sharan AD, Wu C. Gray Matter Sampling Differences Between Subdural Electrodes and Stereoelectroencephalography Electrodes. Front Neurol. 2021; 12:669406. PMID: 33986721.
      Citations:    
    97. Halford JJ, Sperling MR, Arkilo D, Asgharnejad M, Zinger C, Xu R, During M, French JA. A phase 1b/2a study of soticlestat as adjunctive therapy in participants with developmental and/or epileptic encephalopathies. Epilepsy Res. 2021 08; 174:106646. PMID: 33940389.
      Citations:    
    98. Salanova V, Sperling MR, Gross RE, Irwin CP, Vollhaber JA, Giftakis JE, Fisher RS. The SANT? study at 10 years of follow-up: Effectiveness, safety, and sudden unexpected death in epilepsy. Epilepsia. 2021 06; 62(6):1306-1317. PMID: 33830503.
      Citations:    
    99. Doyle GA, Reiner BC, Crist RC, Rao AM, Ojeah NS, Arauco-Shapiro G, Levinson RN, Shah LD, Sperling MR, Ferraro TN, Buono RJ, Berrettini WH. Investigation of long interspersed element-1 retrotransposons as potential risk factors for idiopathic temporal lobe epilepsy. Epilepsia. 2021 06; 62(6):1329-1342. PMID: 33826137.
      Citations:    
    100. Heron SE, Regan BM, Harris RV, Gardner AE, Coleman MJ, Bennett MF, Grinton BE, Helbig KL, Sperling MR, Haut S, Geller EB, Widdess-Walsh P, Pelekanos JT, Bahlo M, Petrovski S, Heinzen EL, Hildebrand MS, Corbett MA, Scheffer IE, G?cz J, Berkovic SF. Association of SLC32A1 Missense Variants With Genetic Epilepsy With Febrile Seizures Plus. Neurology. 2021 05 04; 96(18):e2251-e2260. PMID: 34038384.
      Citations:    
    101. Meisenhelter S, Quon RJ, Steimel SA, Testorf ME, Camp EJ, Moein P, Culler GW, Gross RE, Lega BC, Sperling MR, Kahana MJ, Jobst BC. Interictal Epileptiform Discharges are Task Dependent and are Associated with Lasting Electrocorticographic Changes. Cereb Cortex Commun. 2021; 2(2):tgab019. PMID: 34296164.
      Citations:    
    102. Kang JY, Pickard AA, Bronder J, Yenokyan G, Chen M, Anderson WS, Sperling MR, Nei M. Magnetic resonance-guided laser interstitial thermal therapy: Correlations with seizure outcome. Epilepsia. 2021 05; 62(5):1085-1091. PMID: 33713425.
      Citations:    
    103. Tracy JI, Chaudhary K, Modi S, Crow A, Kumar A, Weinstein D, Sperling MR. Computational support, not primacy, distinguishes compensatory memory reorganization in epilepsy. Brain Commun. 2021; 3(2):fcab025. PMID: 34222865.
      Citations:    
    104. Goldstein L, Dehghan Harati M, Devlin K, Tracy J, Nei M, Skidmore C, Matias CM, Sharan AD, Wu C, Mintzer S, Gorniak R, Sperling MR. Consequences of mesial temporal sparing temporal lobe surgery in medically refractory epilepsy. Epilepsy Behav. 2021 02; 115:107642. PMID: 33360404.
      Citations:    
    105. Quon RJ, Meisenhelter S, Adamovich-Zeitlin RH, Song Y, Steimel SA, Camp EJ, Testorf ME, MacKenzie TA, Gross RE, Lega BC, Sperling MR, Kahana MJ, Jobst BC. Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy. Epilepsia. 2021 02; 62(2):481-491. PMID: 33332586.
      Citations:    
    106. Beniczky S, Rampp S, Asadi-Pooya AA, Rubboli G, Perucca E, Sperling MR. Optimal choice of antiseizure medication: Agreement among experts and validation of a web-based decision support application. Epilepsia. 2021 01; 62(1):220-227. PMID: 33280100.
      Citations:    
    107. Rubinstein DY, Camarillo-Rodriguez L, Serruya MD, Herweg NA, Waldman ZJ, Wanda PA, Sharan AD, Weiss SA, Sperling MR. Contribution of left supramarginal and angular gyri to episodic memory encoding: An intracranial EEG study. Neuroimage. 2021 01 15; 225:117514. PMID: 33137477.
      Citations:    
    108. Umbach G, Kantak P, Jacobs J, Kahana M, Pfeiffer BE, Sperling M, Lega B. Time cells in the human hippocampus and entorhinal cortex support episodic memory. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28463-28474. PMID: 33109718.
      Citations:    
    109. Goldstein L, Margiotta M, Guina ML, Sperling MR, Nei M. Long-term video-EEG monitoring and interictal epileptiform abnormalities. Epilepsy Behav. 2020 12; 113:107523. PMID: 33099258.
      Citations:    
    110. Kang JY, Yenokyan G, Hwang BY, Chen M, Penn R, Mampre D, Sperling MR, Kamath V. Odor identification predicts postoperative seizure control following magnetic resonance-guided laser interstitial thermal therapy. Epilepsia. 2020 09; 61(9):1949-1957. PMID: 32944948.
      Citations:    
    111. Caciagli L, Allen LA, He X, Trimmel K, Vos SB, Centeno M, Galovic M, Sidhu MK, Thompson PJ, Bassett DS, Winston GP, Duncan JS, Koepp MJ, Sperling MR. Thalamus and focal to bilateral seizures: A multiscale cognitive imaging study. Neurology. 2020 10 27; 95(17):e2427-e2441. PMID: 32847951.
      Citations:    
    112. Beniczky S, Rubboli G, Covanis A, Sperling MR. Absence-to-bilateral-tonic-clonic seizure: A generalized seizure type. Neurology. 2020 10 06; 95(14):e2009-e2015. PMID: 32817392.
      Citations:    
    113. Asadi-Pooya AA, Beniczky S, Rubboli G, Sperling MR, Rampp S, Perucca E. A pragmatic algorithm to select appropriate antiseizure medications in patients with epilepsy. Epilepsia. 2020 08; 61(8):1668-1677. PMID: 32697354.
      Citations:    
    114. Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ. Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Neurology. 2020 09 01; 95(9):e1244-e1256. PMID: 32690786.
      Citations:    
    115. Nehlig A, Sperling MR. An interview with Benjamin Tolchin, 2020 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2020 10; 61(10):2065-2066. PMID: 32608502.
      Citations:    
    116. Nehlig A, Sperling M. An interview with Lyndsey Anderson, 2020 Epilepsia Prize Winner for Basic Science Research. Epilepsia. 2020 10; 61(10):2061-2062. PMID: 32608509.
      Citations:    
    117. Mohan UR, Watrous AJ, Miller JF, Lega BC, Sperling MR, Worrell GA, Gross RE, Zaghloul KA, Jobst BC, Davis KA, Sheth SA, Stein JM, Das SR, Gorniak R, Wanda PA, Rizzuto DS, Kahana MJ, Jacobs J. The effects of direct brain stimulation in humans depend on frequency, amplitude, and white-matter proximity. Brain Stimul. 2020 Sep - Oct; 13(5):1183-1195. PMID: 32446925.
      Citations:    
    118. Goyal A, Miller J, Qasim SE, Watrous AJ, Zhang H, Stein JM, Inman CS, Gross RE, Willie JT, Lega B, Lin JJ, Sharan A, Wu C, Sperling MR, Sheth SA, McKhann GM, Smith EH, Schevon C, Jacobs J. Functionally distinct high and low theta oscillations in the human hippocampus. Nat Commun. 2020 05 18; 11(1):2469. PMID: 32424312.
      Citations:    
    119. Sperling MR, Gross RE, Alvarez GE, McKhann GM, Salanova V, Gilmore J. Stereotactic Laser Ablation for Mesial Temporal Lobe Epilepsy: A prospective, multicenter, single-arm study. Epilepsia. 2020 06; 61(6):1183-1189. PMID: 32412094.
      Citations:    
    120. Chung SS, French JA, Kowalski J, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Mizne S, Kamin M. Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures. Neurology. 2020 06 02; 94(22):e2311-e2322. PMID: 32409485.
      Citations:    
    121. Sperling MR, Klein P, Aboumatar S, Gelfand M, Halford JJ, Krauss GL, Rosenfeld WE, Vossler DG, Wechsler R, Borchert L, Kamin M. Cenobamate (YKP3089) as adjunctive treatment for uncontrolled focal seizures in a large, phase 3, multicenter, open-label safety study. Epilepsia. 2020 06; 61(6):1099-1108. PMID: 32396252.
      Citations:    
    122. Bruno E, Viana PF, Sperling MR, Richardson MP. Seizure detection at home: Do devices on the market match the needs of people living with epilepsy and their?caregivers? Epilepsia. 2020 11; 61 Suppl 1:S11-S24. PMID: 32385909.
      Citations:    
    123. Hogan RE, Tarquinio D, Sperling MR, Klein P, Miller I, Segal EB, Rabinowicz AL, Carrazana E. Pharmacokinetics and safety of VALTOCO (NRL-1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri-ictal) and nonseizure (interictal) conditions: A phase 1, open-label study. Epilepsia. 2020 05; 61(5):935-943. PMID: 32338380.
      Citations:    
    124. Weiss SA, Song I, Leng M, Pastore T, Slezak D, Waldman Z, Orosz I, Gorniak R, Donmez M, Sharan A, Wu C, Fried I, Sperling MR, Bragin A, Engel J, Nir Y, Staba R. Ripples Have Distinct Spectral Properties and Phase-Amplitude Coupling With Slow Waves, but Indistinct Unit Firing, in Human Epileptogenic Hippocampus. Front Neurol. 2020; 11:174. PMID: 32292384.
      Citations:    
    125. El Hamrani D, Vives V, Buchholz R, M?me W, Factor C, Fingerhut S, Sperling M, Karst U, Robert P, M?me S. Effect of Long-Term Retention of Gadolinium on Metabolism of Deep Cerebellar Nuclei After Repeated Injections of Gadodiamide in Rats. Invest Radiol. 2020 02; 55(2):120-128. PMID: 31876627.
      Citations:    
    126. Herweg NA, Sharan AD, Sperling MR, Brandt A, Schulze-Bonhage A, Kahana MJ. Reactivated Spatial Context Guides Episodic Recall. J Neurosci. 2020 03 04; 40(10):2119-2128. PMID: 31974207.
      Citations:    
    127. Tsitsiklis M, Miller J, Qasim SE, Inman CS, Gross RE, Willie JT, Smith EH, Sheth SA, Schevon CA, Sperling MR, Sharan A, Stein JM, Jacobs J. Single-Neuron Representations of Spatial Targets in Humans. Curr Biol. 2020 01 20; 30(2):245-253.e4. PMID: 31902728.
      Citations:    
    128. He X, Chaitanya G, Asma B, Caciagli L, Bassett DS, Tracy JI, Sperling MR. Disrupted basal ganglia-thalamocortical loops in focal to bilateral tonic-clonic seizures. Brain. 2020 01 01; 143(1):175-190. PMID: 31860076.
      Citations:    
    129. Surges R, Sperling MR, DeGiorgio CM. Editorial: Sudden Unexpected Death in Epilepsy: Bio-markers, Mechanisms, Risk Identification and Prevention. Front Neurol. 2019; 10:1277. PMID: 31866931.
      Citations:    
    130. Chaitanya G, Hinds W, Kragel J, He X, Sideman N, Ezzyat Y, Sperling MR, Sharan A, Tracy JI. Tonic Resting State Hubness Supports High Gamma Activity Defined Verbal Memory Encoding Network in Epilepsy. Neuroscience. 2020 01 15; 425:194-216. PMID: 31786346.
      Citations:    
    131. Saboo KV, Varatharajah Y, Berry BM, Kremen V, Sperling MR, Davis KA, Jobst BC, Gross RE, Lega B, Sheth SA, Worrell GA, Iyer RK, Kucewicz MT. Unsupervised machine-learning classification of electrophysiologically active electrodes during human cognitive task performance. Sci Rep. 2019 11 22; 9(1):17390. PMID: 31758077.
      Citations:    
    132. Solomon EA, Lega BC, Sperling MR, Kahana MJ. Hippocampal theta codes for distances in semantic and temporal spaces. Proc Natl Acad Sci U S A. 2019 11 26; 116(48):24343-24352. PMID: 31723043.
      Citations:    
    133. Goldstein HE, Smith EH, Gross RE, Jobst BC, Lega BC, Sperling MR, Worrell GA, Zaghloul KA, Wanda PA, Kahana MJ, Rizzuto DS, Schevon CA, McKhann GM, Sheth SA. Risk of seizures induced by intracranial research stimulation: analysis of 770 stimulation sessions. J Neural Eng. 2019 11 11; 16(6):066039. PMID: 31509808.
      Citations:    
    134. Qasim SE, Miller J, Inman CS, Gross RE, Willie JT, Lega B, Lin JJ, Sharan A, Wu C, Sperling MR, Sheth SA, McKhann GM, Smith EH, Schevon C, Stein JM, Jacobs J. Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex. Nat Neurosci. 2019 12; 22(12):2078-2086. PMID: 31712776.
      Citations:    
    135. Fisher RS, Cross H, D'Souza C, French JA, Haut S, Higurashi N, Hirsch E, Jansen FE, Peltola J, Moshe SL, Perucca E, Lagae L, Roulet-Perez E, Schulze-Bonhage A, Scheffer IE, Somerville E, Sperling MR, Wiebe S, Yacubian EM, Zuberi S. Classification as autonomic versus sensory seizures. Epilepsia. 2019 09; 60(9):2003-2005. PMID: 31353460.
      Citations:    
    136. Khambhati AN, Kahn AE, Costantini J, Ezzyat Y, Solomon EA, Gross RE, Jobst BC, Sheth SA, Zaghloul KA, Worrell G, Seger S, Lega BC, Weiss S, Sperling MR, Gorniak R, Das SR, Stein JM, Rizzuto DS, Kahana MJ, Lucas TH, Davis KA, Tracy JI, Bassett DS. Functional control of electrophysiological network architecture using direct neurostimulation in humans. Netw Neurosci. 2019; 3(3):848-877. PMID: 31410383.
      Citations:    
    137. Asadi-Pooya AA, Sperling MR. Normal Awake, Drowsy, and Sleep EEG Patterns That Might Be Overinterpreted as Abnormal. J Clin Neurophysiol. 2019 Jul; 36(4):250-256. PMID: 31274687.
      Citations:    
    138. Nehlig A, Sperling M. An interview with Nicholas Couturier, 2019 Epilepsia Prize Winner for Basic Science Research. Epilepsia. 2019 07; 60(7):1273-1274. PMID: 31162637.
      Citations:    
    139. Nehlig A, Sperling M. An interview with Suejen Perani, 2019 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2019 07; 60(7):1277-1278. PMID: 31162627.
      Citations:    
    140. Wu C, Jermakowicz WJ, Chakravorti S, Cajigas I, Sharan AD, Jagid JR, Matias CM, Sperling MR, Buckley R, Ko A, Ojemann JG, Miller JW, Youngerman B, Sheth SA, McKhann GM, Laxton AW, Couture DE, Popli GS, Smith A, Mehta AD, Ho AL, Halpern CH, Englot DJ, Neimat JS, Konrad PE, Neal E, Vale FL, Holloway KL, Air EL, Schwalb J, Dawant BM, D'Haese PF. Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: A multicenter study of 234 patients. Epilepsia. 2019 06; 60(6):1171-1183. PMID: 31112302.
      Citations:    
    141. Fisher RS, Cross H, D'Souza C, French JA, Haut S, Higurashi N, Hirsch E, Jansen FE, Peltola J, Mosh? SL, Perucca E, Lagae L, Roulet-Perez E, Schulze-Bonhage A, Scheffer IE, Somerville E, Sperling MR, Wiebe S, Yacubian EM, Zuberi S. 2017 International League Against Epilepsy classifications of seizures and epilepsy are steps in the right direction. Epilepsia. 2019 06; 60(6):1040-1044. PMID: 31074833.
      Citations:    
    142. Jobst BC, Ben-Menachem E, Chapman KE, Fu A, Goldman A, Hirsch LJ, Jehi LE, Kossoff EH, Plueger M, Rho JM, Schevon CA, Shinnar S, Sperling MR, Simeone TA, Wagner JL, Lado F. Highlights From the Annual Meeting of the American Epilepsy Society 2018. Epilepsy Curr. 2019 May-Jun; 19(3):152-158. PMID: 31050308.
      Citations:    
    143. Weiss SA, Waldman Z, Raimondo F, Slezak D, Donmez M, Worrell G, Bragin A, Engel J, Staba R, Sperling M. Localizing epileptogenic regions using high-frequency oscillations and machine learning. Biomark Med. 2019 04; 13(5):409-418. PMID: 31044598.
      Citations:    
    144. Shimamoto S, Wu C, Sperling MR. Laser interstitial thermal therapy in drug-resistant epilepsy. Curr Opin Neurol. 2019 04; 32(2):237-245. PMID: 30694919.
      Citations:    
    145. Solomon EA, Stein JM, Das S, Gorniak R, Sperling MR, Worrell G, Inman CS, Tan RJ, Jobst BC, Rizzuto DS, Kahana MJ. Dynamic Theta Networks in the Human Medial Temporal Lobe Support Episodic Memory. Curr Biol. 2019 04 01; 29(7):1100-1111.e4. PMID: 30905609.
      Citations:    
    146. Gurrell R, Gorman D, Whitlock M, Ogden A, Reynolds DS, DiVentura B, Abou-Khalil B, Gelfand M, Pollard J, Hogan RE, Krauss G, Sperling M, Vazquez B, Wechsler RT, Friedman D, Butt RP, French J. Photosensitive epilepsy: Robust clinical efficacy of a selective GABA potentiator. Neurology. 2019 04 09; 92(15):e1786-e1795. PMID: 30877186.
      Citations:    
    147. Kucewicz MT, Saboo K, Berry BM, Kremen V, Miller LR, Khadjevand F, Inman CS, Wanda P, Sperling MR, Gorniak R, Davis KA, Jobst BC, Lega B, Sheth SA, Rizzuto DS, Iyer RK, Kahana MJ, Worrell GA. Human Verbal Memory Encoding Is Hierarchically Distributed in a Continuous Processing Stream. eNeuro. 2019 Jan-Feb; 6(1). PMID: 30847390.
      Citations:    
    148. Weidemann CT, Kragel JE, Lega BC, Worrell GA, Sperling MR, Sharan AD, Jobst BC, Khadjevand F, Davis KA, Wanda PA, Kadel A, Rizzuto DS, Kahana MJ. Neural activity reveals interactions between episodic and semantic memory systems during retrieval. J Exp Psychol Gen. 2019 Jan; 148(1):1-12. PMID: 30596439.
      Citations:    
    149. Gifford AM, Sperling MR, Sharan A, Gorniak RJ, Williams RB, Davis K, Kahana MJ, Cohen YE. Neuronal phase consistency tracks dynamic changes in acoustic spectral regularity. Eur J Neurosci. 2019 05; 49(10):1268-1287. PMID: 30402926.
      Citations:    
    150. Weiss SA, Staba R, Bragin A, Moxon K, Sperling M, Avoli M, Engel J. "Interneurons and principal cell firing in human limbic areas at focal seizure onset". Neurobiol Dis. 2019 04; 124:183-188. PMID: 30471414.
      Citations:    
    151. Clases D, Fingerhut S, Jeibmann A, Sperling M, Doble P, Karst U. LA-ICP-MS/MS improves limits of detection in elemental bioimaging of gadolinium deposition originating from MRI contrast agents in skin and brain tissues. J Trace Elem Med Biol. 2019 Jan; 51:212-218. PMID: 30466933.
      Citations:    
    152. Solomon EA, Kragel JE, Gross R, Lega B, Sperling MR, Worrell G, Sheth SA, Zaghloul KA, Jobst BC, Stein JM, Das S, Gorniak R, Inman CS, Seger S, Rizzuto DS, Kahana MJ. Medial temporal lobe functional connectivity predicts stimulation-induced theta power. Nat Commun. 2018 10 25; 9(1):4437. PMID: 30361627.
      Citations:    
    153. Elahian B, Lado NE, Mankin E, Vangala S, Misra A, Moxon K, Fried I, Sharan A, Yeasin M, Staba R, Bragin A, Avoli M, Sperling MR, Engel J, Weiss SA. Low-voltage fast seizures in humans begin with increased interneuron firing. Ann Neurol. 2018 10; 84(4):588-600. PMID: 30179277.
      Citations:    
    154. Waldman ZJ, Camarillo-Rodriguez L, Chervenova I, Berry B, Shimamoto S, Elahian B, Kucewicz M, Ganne C, He XS, Davis LA, Stein J, Das S, Gorniak R, Sharan AD, Gross R, Inman CS, Lega BC, Zaghloul K, Jobst BC, Davis KA, Wanda P, Khadjevand M, Tracy J, Rizzuto DS, Worrell G, Sperling M, Weiss SA. Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding. Epilepsy Behav. 2018 11; 88:33-40. PMID: 30216929.
      Citations:    
    155. Hinds WA, Misra A, Sperling MR, Sharan A, Tracy JI, Moxon KA. Enhanced co-registration methods to improve intracranial electrode contact localization. Neuroimage Clin. 2018; 20:398-406. PMID: 30128278.
      Citations:    
    156. Weiss SA, Berry B, Chervoneva I, Waldman Z, Guba J, Bower M, Kucewicz M, Brinkmann B, Kremen V, Khadjevand F, Varatharajah Y, Guragain H, Sharan A, Wu C, Staba R, Engel J, Sperling M, Worrell G. Visually validated semi-automatic high-frequency oscillation detection aides the delineation of epileptogenic regions during intra-operative electrocorticography. Clin Neurophysiol. 2018 10; 129(10):2089-2098. PMID: 30077870.
      Citations:    
    157. Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, N?then MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtim?ki T, Wedenoja J, Buring JE, Sch?rks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Veps?l?inen S, Martin NG, Montgomery GW, Kurki MI, H?m?l?inen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, G?bel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono RJ, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, K?lvi?inen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, M?ller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Juli? A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, S?nchez-Mora C, Ribas?s M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, B?rglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, et al. Analysis of shared heritability in common disorders of the brain. Science. 2018 06 22; 360(6395). PMID: 29930110.
      Citations:    
    158. Miller J, Watrous AJ, Tsitsiklis M, Lee SA, Sheth SA, Schevon CA, Smith EH, Sperling MR, Sharan A, Asadi-Pooya AA, Worrell GA, Meisenhelter S, Inman CS, Davis KA, Lega B, Wanda PA, Das SR, Stein JM, Gorniak R, Jacobs J. Lateralized hippocampal oscillations underlie distinct aspects of human spatial memory and navigation. Nat Commun. 2018 06 21; 9(1):2423. PMID: 29930307.
      Citations:    
    159. Robert P, Fingerhut S, Factor C, Vives V, Letien J, Sperling M, Rasschaert M, Santus R, Ballet S, Id?e JM, Corot C, Karst U. One-year Retention of Gadolinium in the Brain: Comparison of Gadodiamide and Gadoterate Meglumine in a Rodent Model. Radiology. 2018 08; 288(2):424-433. PMID: 29786486.
      Citations:    
    160. Sperling M, Nehlig A. An interview with Divyanshu Dubey, 2018 Epilepsia Prize winner for clinical research. Epilepsia. 2018 06; 59(6):1094-1095. PMID: 29782048.
      Citations:    
    161. Nehlig A, Sperling M. An interview with Kyle Thomson, 2018 Epilepsia Prize Winner for Basic Science Research. Epilepsia. 2018 06; 59(6):1091-1092. PMID: 29782056.
      Citations:    
    162. Fingerhut S, Sperling M, Holling M, Niederstadt T, Allkemper T, Radbruch A, Heindel W, Paulus W, Jeibmann A, Karst U. Gadolinium-based contrast agents induce gadolinium deposits in cerebral vessel walls, while the neuropil is not affected: an autopsy study. Acta Neuropathol. 2018 07; 136(1):127-138. PMID: 29748901.
      Citations:    
    163. He X, Bassett DS, Chaitanya G, Sperling MR, Kozlowski L, Tracy JI. Disrupted dynamic network reconfiguration of the language system in temporal lobe epilepsy. Brain. 2018 05 01; 141(5):1375-1389. PMID: 29554279.
      Citations:    
    164. Goyal A, Miller J, Watrous AJ, Lee SA, Coffey T, Sperling MR, Sharan A, Worrell G, Berry B, Lega B, Jobst BC, Davis KA, Inman C, Sheth SA, Wanda PA, Ezzyat Y, Das SR, Stein J, Gorniak R, Jacobs J. Electrical Stimulation in Hippocampus and Entorhinal Cortex Impairs Spatial and Temporal Memory. J Neurosci. 2018 05 09; 38(19):4471-4481. PMID: 29636396.
      Citations:    
    165. Altalib HH, Berg AT, Cong X, Vickrey BG, Sperling MR, Shinnar S, Langfitt JT, Walczak TS, Bazil CW, Sukumar N, Devinsky O. Presurgical depression and anxiety are not associated with worse epilepsy surgery outcome five years postoperatively. Epilepsy Behav. 2018 06; 83:7-12. PMID: 29631157.
      Citations:    
    166. Kucewicz MT, Berry BM, Miller LR, Khadjevand F, Ezzyat Y, Stein JM, Kremen V, Brinkmann BH, Wanda P, Sperling MR, Gorniak R, Davis KA, Jobst BC, Gross RE, Lega B, Van Gompel J, Stead SM, Rizzuto DS, Kahana MJ, Worrell GA. Evidence for verbal memory enhancement with electrical brain stimulation in the lateral temporal cortex. Brain. 2018 04 01; 141(4):971-978. PMID: 29324988.
      Citations:    
    167. Goldenholz DM, Moss R, Jost DA, Crone NE, Krauss G, Picard R, Caborni C, Cavazos JE, Hixson J, Loddenkemper T, Salazar TD, Lubbers L, Harte-Hargrove LC, Whittemore V, Duun-Henriksen J, Dolan E, Kasturia N, Oberemk M, Cook MJ, Lehmkuhle M, Sperling MR, Shafer PO. Common data elements for epilepsy mobile health systems. Epilepsia. 2018 05; 59(5):1020-1026. PMID: 29604050.
      Citations:    
    168. Sideman N, Chaitanya G, He X, Doucet G, Kim NY, Sperling MR, Sharan AD, Tracy JI. Task activation and functional connectivity show concordant memory laterality in temporal lobe epilepsy. Epilepsy Behav. 2018 04; 81:70-78. PMID: 29499551.
      Citations:    
    169. Vakharia VN, Sparks R, Li K, O'Keeffe AG, Miserocchi A, McEvoy AW, Sperling MR, Sharan A, Ourselin S, Duncan JS, Wu C. Automated trajectory planning for laser interstitial thermal therapy in mesial temporal lobe epilepsy. Epilepsia. 2018 04; 59(4):814-824. PMID: 29528488.
      Citations:    
    170. Lee SA, Miller JF, Watrous AJ, Sperling MR, Sharan A, Worrell GA, Berry BM, Aronson JP, Davis KA, Gross RE, Lega B, Sheth S, Das SR, Stein JM, Gorniak R, Rizzuto DS, Jacobs J. Electrophysiological Signatures of Spatial Boundaries in the Human Subiculum. J Neurosci. 2018 03 28; 38(13):3265-3272. PMID: 29467145.
      Citations:    
    171. Pazdera L, Sperling MR, Harvey JH, Sam MC, Strom LA, Blum D, Grinnell T, Cheng H. Efficacy and safety of eslicarbazepine acetate monotherapy in patients converting from carbamazepine. Epilepsia. 2018 03; 59(3):704-714. PMID: 29450890.
      Citations:    
    172. Misra A, Long X, Sperling MR, Sharan AD, Moxon KA. Increased neuronal synchrony prepares mesial temporal networks for seizures of neocortical origin. Epilepsia. 2018 03; 59(3):636-649. PMID: 29442363.
      Citations:    
    173. Ezzyat Y, Wanda PA, Levy DF, Kadel A, Aka A, Pedisich I, Sperling MR, Sharan AD, Lega BC, Burks A, Gross RE, Inman CS, Jobst BC, Gorenstein MA, Davis KA, Worrell GA, Kucewicz MT, Stein JM, Gorniak R, Das SR, Rizzuto DS, Kahana MJ. Closed-loop stimulation of temporal cortex rescues functional networks and improves memory. Nat Commun. 2018 02 06; 9(1):365. PMID: 29410414.
      Citations:    
    174. Kucewicz MT, Berry BM, Kremen V, Miller LR, Khadjevand F, Ezzyat Y, Stein JM, Wanda P, Sperling MR, Gorniak R, Davis KA, Jobst BC, Gross RE, Lega B, Stead SM, Rizzuto DS, Kahana MJ, Worrell GA. Electrical Stimulation Modulates High ? Activity and Human Memory Performance. eNeuro. 2018 Jan-Feb; 5(1). PMID: 29404403.
      Citations:    
    175. Ryvlin P, So EL, Gordon CM, Hesdorffer DC, Sperling MR, Devinsky O, Bunker MT, Olin B, Friedman D. Long-term surveillance of SUDEP in drug-resistant epilepsy patients treated with VNS therapy. Epilepsia. 2018 03; 59(3):562-572. PMID: 29336017.
      Citations:    
    176. Solomon EA, Kragel JE, Sperling MR, Sharan A, Worrell G, Kucewicz M, Inman CS, Lega B, Davis KA, Stein JM, Jobst BC, Zaghloul KA, Sheth SA, Rizzuto DS, Kahana MJ. Widespread theta synchrony and high-frequency desynchronization underlies enhanced cognition. Nat Commun. 2017 11 22; 8(1):1704. PMID: 29167419.
      Citations:    
    177. Shimamoto S, Waldman ZJ, Orosz I, Song I, Bragin A, Fried I, Engel J, Staba R, Sharan A, Wu C, Sperling MR, Weiss SA. Utilization of independent component analysis for accurate pathological ripple detection in intracranial EEG recordings recorded extra- and intra-operatively. Clin Neurophysiol. 2018 01; 129(1):296-307. PMID: 29113719.
      Citations:    
    178. Waldman ZJ, Shimamoto S, Song I, Orosz I, Bragin A, Fried I, Engel J, Staba R, Sperling MR, Weiss SA. A method for the topographical identification and quantification of high frequency oscillations in intracranial electroencephalography recordings. Clin Neurophysiol. 2018 01; 129(1):308-318. PMID: 29122445.
      Citations:    
    179. Fingerhut S, Niehoff AC, Sperling M, Jeibmann A, Paulus W, Niederstadt T, Allkemper T, Heindel W, Holling M, Karst U. Spatially resolved quantification of gadolinium deposited in the brain of a patient treated with gadolinium-based contrast agents. J Trace Elem Med Biol. 2018 Jan; 45:125-130. PMID: 29173468.
      Citations:    
    180. Halford JJ, Sperling MR, Nair DR, Dlugos DJ, Tatum WO, Harvey J, French JA, Pollard JR, Faught E, Noe KH, Henry TR, Jetter GM, Lie OV, Morgan LC, Girouard MR, Cardenas DP, Whitmire LE, Cavazos JE. Detection of generalized tonic-clonic seizures using surface electromyographic monitoring. Epilepsia. 2017 11; 58(11):1861-1869. PMID: 28980702.
      Citations:    
    181. Song I, Orosz I, Chervoneva I, Waldman ZJ, Fried I, Wu C, Sharan A, Salamon N, Gorniak R, Dewar S, Bragin A, Engel J, Sperling MR, Staba R, Weiss SA. Bimodal coupling of ripples and slower oscillations during sleep in patients with focal epilepsy. Epilepsia. 2017 11; 58(11):1972-1984. PMID: 28948998.
      Citations:    
    182. Asadi-Pooya AA, Dlugos D, Skidmore C, Sperling MR. Atlas of Electroencephalography, 3rd Edition. Epileptic Disord. 2017 Sep 01; 19(3):384. PMID: 28872032.
      Citations:    
    183. Kang JY, Sperling MR. Epileptologist's view: Laser interstitial thermal ablation for treatment of temporal lobe epilepsy. Epilepsy Res. 2018 05; 142:149-152. PMID: 28774708.
      Citations:    
    184. Fisher RS, Helen Cross J, D'Souza C, French JA, Haut S, Higurashi N, Hirsch E, Jansen FE, Lagae L, Moshe SL, Korey SR, Purpura DP, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Response to the numbering of seizure types. Epilepsia. 2017 07; 58(7):1300-1301. PMID: 28677853.
      Citations:    
    185. Nehlig A, Sperling M, Mathern G. An interview with Tiwalade Sobayo, 2017 Epilepsia Prize Winner for Basic Science Research. Epilepsia. 2017 07; 58(7):1115-1116. PMID: 28677858.
      Citations:    
    186. Nehlig A, Sperling M, Mathern G. An interview with Sarah Weckhuysen, 2017 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2017 07; 58(7):1119-1120. PMID: 28677854.
      Citations:    
    187. He X, Doucet GE, Pustina D, Sperling MR, Sharan AD, Tracy JI. Presurgical thalamic "hubness" predicts surgical outcome in temporal lobe epilepsy. Neurology. 2017 Jun 13; 88(24):2285-2293. PMID: 28515267.
      Citations:    
    188. Asadi-Pooya AA, Sperling MR, Chung S, Klein P, Diaz A, Elmoufti S, Schiemann J, Whitesides J. Erratum to "Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: A post-hoc study" [Epilepsy Res. 131 (2017) 70-75]. Epilepsy Res. 2017 11; 137:165-166. PMID: 28501260.
      Citations:    
    189. Kucewicz MT, Berry BM, Kremen V, Brinkmann BH, Sperling MR, Jobst BC, Gross RE, Lega B, Sheth SA, Stein JM, Das SR, Gorniak R, Stead SM, Rizzuto DS, Kahana MJ, Worrell GA. Dissecting gamma frequency activity during human memory processing. Brain. 2017 May 01; 140(5):1337-1350. PMID: 28335018.
      Citations:    
    190. Ezzyat Y, Kragel JE, Burke JF, Levy DF, Lyalenko A, Wanda P, O'Sullivan L, Hurley KB, Busygin S, Pedisich I, Sperling MR, Worrell GA, Kucewicz MT, Davis KA, Lucas TH, Inman CS, Lega BC, Jobst BC, Sheth SA, Zaghloul K, Jutras MJ, Stein JM, Das SR, Gorniak R, Rizzuto DS, Kahana MJ. Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans. Curr Biol. 2017 May 08; 27(9):1251-1258. PMID: 28434860.
      Citations:    
    191. Aschner M, Palinski C, Sperling M, Karst U, Schwerdtle T, Bornhorst J. Imaging metals in Caenorhabditis elegans. Metallomics. 2017 04 19; 9(4):357-364. PMID: 28054081.
      Citations:    
    192. Kragel JE, Ezzyat Y, Sperling MR, Gorniak R, Worrell GA, Berry BM, Inman C, Lin JJ, Davis KA, Das SR, Stein JM, Jobst BC, Zaghloul KA, Sheth SA, Rizzuto DS, Kahana MJ. Similar patterns of neural activity predict memory function during encoding and retrieval. Neuroimage. 2017 07 15; 155:60-71. PMID: 28377210.
      Citations:    
    193. Long NM, Sperling MR, Worrell GA, Davis KA, Gross RE, Lega BC, Jobst BC, Sheth SA, Zaghloul K, Stein JM, Kahana MJ. Contextually Mediated Spontaneous Retrieval Is Specific to the Hippocampus. Curr Biol. 2017 Apr 03; 27(7):1074-1079. PMID: 28343962.
      Citations:    
    194. Ngo L, Sperling MR, Skidmore C, Mintzer S, Nei M. Absolute spike frequency as a predictor of surgical outcome in temporal lobe epilepsy. Seizure. 2017 Apr; 47:83-86. PMID: 28342319.
      Citations:    
    195. Fisher RS, Cross JH, D'Souza C, French JA, Haut SR, Higurashi N, Hirsch E, Jansen FE, Lagae L, Mosh? SL, Peltola J, Roulet Perez E, Scheffer IE, Schulze-Bonhage A, Somerville E, Sperling M, Yacubian EM, Zuberi SM. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia. 2017 04; 58(4):531-542. PMID: 28276064.
      Citations:    
    196. Asadollahi M, Sperling MR, Rabiei AH, Asadi-Pooya AA. Drug-resistant parietal lobe epilepsy: clinical manifestations and surgery outcome. Epileptic Disord. 2017 Mar 01; 19(1):35-39. PMID: 28256447.
      Citations:    
    197. Asadi-Pooya AA, Sperling MR, Chung S, Klein P, Diaz A, Elmoufti S, Schiemann J, Whitesides J. Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: A post-hoc study. Epilepsy Res. 2017 Mar; 131:70-75. PMID: 28279891.
      Citations:    
    198. Sperling MR, Klein P, Tsai J. Randomized, double-blind, placebo-controlled phase 2 study of ganaxolone as add-on therapy in adults with uncontrolled partial-onset seizures. Epilepsia. 2017 04; 58(4):558-564. PMID: 28230252.
      Citations:    
    199. Doucet GE, He X, Sperling MR, Sharan A, Tracy JI. From "rest" to language task: Task activation selects and prunes from broader resting-state network. Hum Brain Mapp. 2017 05; 38(5):2540-2552. PMID: 28195438.
      Citations:    
    200. Asadi-Pooya AA, Nei M, Centurion EE, Lorenzo M, Sperling MR. Postsurgical outcome in patients with olfactory auras and drug-resistant epilepsy. Epilepsy Behav. 2017 03; 68:8-10. PMID: 28109994.
      Citations:    
    201. Weiss SA, Asadi-Pooya AA, Vangala S, Moy S, Wyeth DH, Orosz I, Gibbs M, Schrader L, Lerner J, Cheng CK, Chang E, Rajaraman R, Keselman I, Churchman P, Bower-Baca C, Numis AL, Ho MG, Rao L, Bhat A, Suski J, Asadollahi M, Ambrose T, Fernandez A, Nei M, Skidmore C, Mintzer S, Eliashiv DS, Mathern GW, Nuwer MR, Sperling M, Engel J, Stern JM. AR2, a novel automatic muscle artifact reduction software method for ictal EEG interpretation: Validation and comparison of performance with commercially available software. F1000Res. 2017; 6:30. PMID: 28491280.
      Citations:    
    202. Kang JY, Sperling MR. Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Treatment of Drug-Resistant Epilepsy. Neurotherapeutics. 2017 01; 14(1):176-181. PMID: 27905093.
      Citations:    
    203. Merkow MB, Burke JF, Ramayya AG, Sharan AD, Sperling MR, Kahana MJ. Stimulation of the human medial temporal lobe between learning and recall selectively enhances forgetting. Brain Stimul. 2017 May - Jun; 10(3):645-650. PMID: 28073638.
      Citations:    
    204. Asadi-Pooya AA, Wyeth D, Nei M, Sharan AD, Sperling MR. Postsurgical outcome in patients with auditory auras and drug-resistant epilepsy. Epilepsy Behav. 2017 01; 66:49-52. PMID: 28033545.
      Citations:    
    205. Carre?o M, Bien CG, Asadi-Pooya AA, Sperling M, Marusic P, Elisak M, Pimentel J, Wehner T, Mohanraj R, Uranga J, G?mez-Ib??ez A, Villanueva V, Gil F, Donaire A, Bargall? N, Rumi? J, Rold?n P, Setoain X, Pintor L, Boget T, Bailles E, Falip M, Aparicio J, Dalmau J, Graus F. Epilepsy surgery in drug resistant temporal lobe epilepsy associated with neuronal antibodies. Epilepsy Res. 2017 01; 129:101-105. PMID: 28043058.
      Citations:    
    206. Horak PC, Meisenhelter S, Song Y, Testorf ME, Kahana MJ, Viles WD, Bujarski KA, Connolly AC, Robbins AA, Sperling MR, Sharan AD, Worrell GA, Miller LR, Gross RE, Davis KA, Roberts DW, Lega B, Sheth SA, Zaghloul KA, Stein JM, Das SR, Rizzuto DS, Jobst BC. Interictal epileptiform discharges impair word recall in multiple brain areas. Epilepsia. 2017 03; 58(3):373-380. PMID: 27935031.
      Citations:    
    207. Jacobs J, Miller J, Lee SA, Coffey T, Watrous AJ, Sperling MR, Sharan A, Worrell G, Berry B, Lega B, Jobst BC, Davis K, Gross RE, Sheth SA, Ezzyat Y, Das SR, Stein J, Gorniak R, Kahana MJ, Rizzuto DS. Direct Electrical Stimulation of the Human Entorhinal Region and Hippocampus Impairs Memory. Neuron. 2016 Dec 07; 92(5):983-990. PMID: 27930911.
      Citations:    
    208. Kinney MO, Sperling MR, Barshow S, Nei M, Asadi-Pooya AA. A reappraisal of mortality after epilepsy surgery. Neurology. 2016 11 08; 87(19):2067. PMID: 27821566.
      Citations:    
    209. Gutierrez C, Asadi-Pooya AA, Skidmore CT, Tobochnik SD, LoPinto-Khoury C, Sperling MR. Clinical features and postoperative seizure outcome in patients with drug-resistant gelastic seizures without hypothalamic hamartoma. Epilepsy Behav. 2016 11; 64(Pt A):90-93. PMID: 27736662.
      Citations:    
    210. Asadi-Pooya AA, Asadollahi M, Bujarski K, Rabiei AH, Aminian N, Wyeth D, Sperling MR. Ictal verbal help-seeking: Occurrence and the underlying etiology. Epilepsy Behav. 2016 11; 64(Pt A):15-17. PMID: 27723496.
      Citations:    
    211. Bhamidipati D, Goldhammer JE, Sperling MR, Torjman MC, McCarey MM, Whellan DJ. Cognitive Outcomes After Coronary Artery Bypass Grafting. J Cardiothorac Vasc Anesth. 2017 04; 31(2):707-718. PMID: 28094177.
      Citations:    
    212. Atsina KB, Sharan AD, Wu C, Evans JJ, Sperling MR, Skidmore CT, Gorniak RJ. JOURNAL CLUB: Longitudinal Qualitative Characterization of MRI Features After Laser Interstitial Thermal Therapy in Drug-Resistant Epilepsy. AJR Am J Roentgenol. 2017 Jan; 208(1):48-56. PMID: 27657929.
      Citations:    
    213. Robinson LF, He X, Barnett P, Doucet GE, Sperling MR, Sharan A, Tracy JI. The Temporal Instability of Resting State Network Connectivity in Intractable Epilepsy. Hum Brain Mapp. 2017 01; 38(1):528-540. PMID: 27628031.
      Citations:    
    214. Moseley BD, Sperling MR, Asadi-Pooya AA, Diaz A, Elmouft S, Schiemann J, Whitesides J. Efficacy, safety, and tolerability of adjunctive brivaracetam for secondarily generalized tonic-clonic seizures: Pooled results from three Phase III studies. Epilepsy Res. 2016 Nov; 127:179-185. PMID: 27608437.
      Citations:    
    215. Asadi-Pooya AA, Rabiei AH, Gracely EJ, Sperling MR. Remote preoperative tonic-clonic seizures do not influence outcome after surgery for temporal lobe epilepsy. J Neurol Sci. 2016 Oct 15; 369:330-332. PMID: 27653919.
      Citations:    
    216. Asadi-Pooya AA, Asadollahi M, Tinker J, Nei M, Sperling MR. Post-epilepsy surgery psychogenic nonepileptic seizures. Epilepsia. 2016 Oct; 57(10):1691-1696. PMID: 27554951.
      Citations:    
    217. Schmidt RF, Wu C, Lang MJ, Soni P, Williams KA, Boorman DW, Evans JJ, Sperling MR, Sharan AD. Complications of subdural and depth electrodes in 269 patients undergoing 317 procedures for invasive monitoring in epilepsy. Epilepsia. 2016 Oct; 57(10):1697-1708. PMID: 27549686.
      Citations:    
    218. Nehlig A, Sperling M, Mathern G. An interview with Saadet Mahmutoglu, 2016 Epilepsia prize winner for Clinical Research. Epilepsia. 2016 09; 57(9):1343-4. PMID: 27522448.
      Citations:    
    219. Nehlig A, Sperling M, Mathern G. Interview with Lena Nguyen, 2016 Epilepsia prize winner for Basic Science Research. Epilepsia. 2016 09; 57(9):1347-8. PMID: 27522480.
      Citations:    
    220. Asadi-Pooya AA, Nei M, Sharan A, Sperling MR. Seizure clusters in drug-resistant focal epilepsy. Epilepsia. 2016 09; 57(9):e187-90. PMID: 27417685.
      Citations:    
    221. Finamore JM, Sperling MR, Zhan T, Nei M, Skidmore CT, Mintzer S. Seizure outcome after switching antiepileptic drugs: A matched, prospective study. Epilepsia. 2016 08; 57(8):1294-300. PMID: 27396435.
      Citations:    
    222. Asadi-Pooya AA, Asadollahi M, Sperling MR. Ictal pain: occurrence, clinical features, and underlying etiologies. Epilepsy Behav. 2016 08; 61:59-62. PMID: 27315133.
      Citations:    
    223. Fuertinger S, Simonyan K, Sperling MR, Sharan AD, Hamzei-Sichani F. High-frequency brain networks undergo modular breakdown during epileptic seizures. Epilepsia. 2016 07; 57(7):1097-108. PMID: 27221325.
      Citations:    
    224. Lhatoo SD, Nei M, Raghavan M, Sperling M, Zonjy B, Lacuey N, Devinsky O. Nonseizure SUDEP: Sudden unexpected death in epilepsy without preceding epileptic seizures. Epilepsia. 2016 07; 57(7):1161-8. PMID: 27221596.
      Citations:    
    225. Asadi-Pooya AA, Asadollahi M, Shimamoto S, Lorenzo M, Sperling MR. Spike voltage topography in temporal lobe epilepsy. J Neurol Sci. 2016 Jul 15; 366:209-212. PMID: 27288809.
      Citations:    
    226. Doucet GE, He X, Sperling M, Sharan A, Tracy JI. Gray Matter Abnormalities in Temporal Lobe Epilepsy: Relationships with Resting-State Functional Connectivity and Episodic Memory Performance. PLoS One. 2016; 11(5):e0154660. PMID: 27171178.
      Citations:    
    227. Isojarvi J, Lee D, Peng G, Sperling MR. Clobazam-treated patients with Lennox-Gastaut syndrome experienced fewer seizure-related injuries than placebo patients during trial OV-1012. Epilepsia. 2016 Jun; 57(6):e113-6. PMID: 27145465.
      Citations:    
    228. Sperling MR, Barshow S, Nei M, Asadi-Pooya AA. A reappraisal of mortality after epilepsy surgery. Neurology. 2016 05 24; 86(21):1938-44. PMID: 27164679.
      Citations:    
    229. Asadi-Pooya AA, Wyeth D, Sperling MR. Ictal crying. Epilepsy Behav. 2016 06; 59:1-3. PMID: 27084975.
      Citations:    
    230. Asadi-Pooya AA, Nei M, Sharan A, Sperling MR. Patient Historical Risk Factors Associated with Seizure Outcome After Surgery for Drug-Resistant Nonlesional Temporal Lobe Epilepsy. World Neurosurg. 2016 Jul; 91:205-9. PMID: 27086259.
      Citations:    
    231. Mintzer S, Miller R, Shah K, Chervoneva I, Nei M, Skidmore C, Sperling MR. Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. Epilepsy Behav. 2016 05; 58:127-32. PMID: 27074299.
      Citations:    
    232. Hansen M, Scheltema MJ, Sonne DP, Hansen JS, Sperling M, Rehfeld JF, Holst JJ, Vilsb?ll T, Knop FK. Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion. Diabetes Obes Metab. 2016 06; 18(6):571-80. PMID: 26888164.
      Citations:    
    233. Asadi-Pooya AA, Nei M, Sharan A, Sperling MR. Auras in patients with temporal lobe epilepsy and mesial temporal sclerosis. J Neurol Sci. 2016 May 15; 364:24-6. PMID: 27084209.
      Citations:    
    234. Sperling MR, French J, Jacobson MP, Pazdera L, Gough M, Cheng H, Grinnell T, Blum D. Conversion to eslicarbazepine acetate monotherapy: A pooled analysis of 2 phase III studies. Neurology. 2016 Mar 22; 86(12):1095-102. PMID: 26911639.
      Citations:    
    235. Nei M, Mintzer S, Skidmore C, Sperling MR, Ho RT. Heart rate and blood pressure in sudden unexpected death in epilepsy (SUDEP). Epilepsy Res. 2016 May; 122:44-6. PMID: 26921856.
      Citations:    
    236. Asadi-Pooya AA, Nei M, Sharan A, Sperling MR. Historical Risk Factors Associated with Seizure Outcome After Surgery for Drug-Resistant Mesial Temporal Lobe Epilepsy. World Neurosurg. 2016 May; 89:78-83. PMID: 26875655.
      Citations:    
    237. Asadi-Pooya AA, Nei M, Rostami C, Sperling MR. Mesial temporal lobe epilepsy with childhood febrile seizure. Acta Neurol Scand. 2017 Jan; 135(1):88-91. PMID: 26861129.
      Citations:    
    238. Kang JY, Wu C, Tracy J, Lorenzo M, Evans J, Nei M, Skidmore C, Mintzer S, Sharan AD, Sperling MR. Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy. Epilepsia. 2016 Feb; 57(2):325-34. PMID: 26697969.
      Citations:    
    239. Asadi-Pooya AA, Rostami C, Rabiei AH, Sperling MR. Factors associated with tonic-clonic seizures in patients with drug-resistant mesial temporal epilepsy. J Neurol Sci. 2015 Dec 15; 359(1-2):452-4. PMID: 26490320.
      Citations:    
    240. Klein P, Schiemann J, Sperling MR, Whitesides J, Liang W, Stalvey T, Brandt C, Kwan P. A randomized, double-blind, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy and safety of adjunctive brivaracetam in adult patients with uncontrolled partial-onset seizures. Epilepsia. 2015 Dec; 56(12):1890-8. PMID: 26471380.
      Citations:    
    241. Osipowicz K, Sperling MR, Sharan AD, Tracy JI. Functional MRI, resting state fMRI, and DTI for predicting verbal fluency outcome following resective surgery for temporal lobe epilepsy. J Neurosurg. 2016 Apr; 124(4):929-37. PMID: 26406797.
      Citations:    
    242. Asadi-Pooya AA, Nei M, Sperling MR. Seasonality of birth in patients with temporal lobe epilepsy. Acta Neurol Scand. 2016 Jul; 134(1):87-9. PMID: 26392391.
      Citations:    
    243. Doucet GE, He X, Sperling M, Sharan A, Tracy JI. Frontal gray matter abnormalities predict seizure outcome in refractory temporal lobe epilepsy patients. Neuroimage Clin. 2015; 9:458-66. PMID: 26594628.
      Citations:    
    244. Jehi L, Friedman D, Carlson C, Cascino G, Dewar S, Elger C, Engel J, Knowlton R, Kuzniecky R, McIntosh A, O'Brien TJ, Spencer D, Sperling MR, Worrell G, Bingaman B, Gonzalez-Martinez J, Doyle W, French J. The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia. Epilepsia. 2015 Oct; 56(10):1526-33. PMID: 26250432.
      Citations:    
    245. Pustina D, Avants B, Sperling M, Gorniak R, He X, Doucet G, Barnett P, Mintzer S, Sharan A, Tracy J. Predicting the laterality of temporal lobe epilepsy from PET, MRI, and DTI: A multimodal study. Neuroimage Clin. 2015; 9:20-31. PMID: 26288753.
      Citations:    
    246. Asadi-Pooya AA, Nei M, Sharan A, Sperling MR. Type of preoperative aura may predict postsurgical outcome in patients with temporal lobe epilepsy and mesial temporal sclerosis. Epilepsy Behav. 2015 Sep; 50:98-100. PMID: 26209944.
      Citations:    
    247. He X, Doucet GE, Sperling M, Sharan A, Tracy JI. Reduced thalamocortical functional connectivity in temporal lobe epilepsy. Epilepsia. 2015 Oct; 56(10):1571-9. PMID: 26193910.
      Citations:    
    248. Diamond M, Mathern G, Nehlig A, Sperling M. Interview with Matthew Diamond, 2014 Epilepsia prize winner. Epilepsia. 2015 Jul; 56(7):987-8. PMID: 26041101.
      Citations:    
    249. Asadi-Pooya AA, Sperling MR. Age at onset in patients with medically refractory temporal lobe epilepsy and mesial temporal sclerosis: impact on clinical manifestations and postsurgical outcome. Seizure. 2015 Aug; 30:42-5. PMID: 26216683.
      Citations:    
    250. King-Stephens D, Mirro E, Weber PB, Laxer KD, Van Ness PC, Salanova V, Spencer DC, Heck CN, Goldman A, Jobst B, Shields DC, Bergey GK, Eisenschenk S, Worrell GA, Rossi MA, Gross RE, Cole AJ, Sperling MR, Nair DR, Gwinn RP, Park YD, Rutecki PA, Fountain NB, Wharen RE, Hirsch LJ, Miller IO, Barkley GL, Edwards JC, Geller EB, Berg MJ, Sadler TL, Sun FT, Morrell MJ. Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography. Epilepsia. 2015 Jun; 56(6):959-67. PMID: 25988840.
      Citations:    
    251. Asadi-Pooya AA, Sperling MR. Epidemiology of psychogenic nonepileptic seizures. Epilepsy Behav. 2015 May; 46:60-5. PMID: 25882323.
      Citations:    
    252. Herzog AG, Fowler KM, Sperling MR, Massaro JM. Distribution of seizures across the menstrual cycle in women with epilepsy. Epilepsia. 2015 May; 56(5):e58-62. PMID: 25823700.
      Citations:    
    253. Appel S, Sharan AD, Tracy JI, Evans J, Sperling MR. A comparison of occipital and temporal lobe epilepsies. Acta Neurol Scand. 2015 Oct; 132(4):284-90. PMID: 25809072.
      Citations:    
    254. Doucet GE, Rider R, Taylor N, Skidmore C, Sharan A, Sperling M, Tracy JI. Presurgery resting-state local graph-theory measures predict neurocognitive outcomes after brain surgery in temporal lobe epilepsy. Epilepsia. 2015 Apr; 56(4):517-26. PMID: 25708625.
      Citations:    
    255. Sperling MR, Harvey J, Grinnell T, Cheng H, Blum D. Efficacy and safety of conversion to monotherapy with eslicarbazepine acetate in adults with uncontrolled partial-onset seizures: a randomized historical-control phase III study based in North America. Epilepsia. 2015 Apr; 56(4):546-55. PMID: 25689448.
      Citations:    
    256. Strozzi I, Nolan SJ, Sperling MR, Wingerchuk DM, Sirven J. Early versus late antiepileptic drug withdrawal for people with epilepsy in remission. Cochrane Database Syst Rev. 2015 Feb 11; (2):CD001902. PMID: 25922863.
      Citations:    
    257. Salanova V, Witt T, Worth R, Henry TR, Gross RE, Nazzaro JM, Labar D, Sperling MR, Sharan A, Sandok E, Handforth A, Stern JM, Chung S, Henderson JM, French J, Baltuch G, Rosenfeld WE, Garcia P, Barbaro NM, Fountain NB, Elias WJ, Goodman RR, Pollard JR, Tr?ster AI, Irwin CP, Lambrecht K, Graves N, Fisher R. Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy. Neurology. 2015 Mar 10; 84(10):1017-25. PMID: 25663221.
      Citations:    
    258. Larsen DP, Butler AC, Aung WY, Corboy JR, Friedman DI, Sperling MR. The effects of test-enhanced learning on long-term retention in AAN annual meeting courses. Neurology. 2015 Feb 17; 84(7):748-54. PMID: 25609761.
      Citations:    
    259. Sperling MR, Abou-Khalil B, Harvey J, Rogin JB, Biraben A, Galimberti CA, Kowacs PA, Hong SB, Cheng H, Blum D, Nunes T, Soares-da-Silva P. Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial-onset seizures: Results of a phase III, double-blind, randomized, placebo-controlled trial. Epilepsia. 2015 Feb; 56(2):244-53. PMID: 25528898.
      Citations:    
    260. Doucet GE, Pustina D, Skidmore C, Sharan A, Sperling MR, Tracy JI. Resting-state functional connectivity predicts the strength of hemispheric lateralization for language processing in temporal lobe epilepsy and normals. Hum Brain Mapp. 2015 Jan; 36(1):288-303. PMID: 25187327.
      Citations:    
    261. Sperling MR, Haas KF, Krauss G, Seif Eddeine H, Henney HR, Rabinowicz AL, Bream G, Squillacote D, Carrazana EJ. Dosing feasibility and tolerability of intranasal diazepam in adults with epilepsy. Epilepsia. 2014 Oct; 55(10):1544-50. PMID: 25154625.
      Citations:    
    262. Burke JF, Sharan AD, Sperling MR, Ramayya AG, Evans JJ, Healey MK, Beck EN, Davis KA, Lucas TH, Kahana MJ. Theta and high-frequency activity mark spontaneous recall of episodic memories. J Neurosci. 2014 Aug 20; 34(34):11355-65. PMID: 25143616.
      Citations:    
    263. Pustina D, Doucet G, Sperling M, Sharan A, Tracy J. Increased microstructural white matter correlations in left, but not right, temporal lobe epilepsy. Hum Brain Mapp. 2015 Jan; 36(1):85-98. PMID: 25137314.
      Citations:    
    264. Pustina D, Doucet G, Evans J, Sharan A, Sperling M, Skidmore C, Tracy J. Distinct types of white matter changes are observed after anterior temporal lobectomy in epilepsy. PLoS One. 2014; 9(8):e104211. PMID: 25089698.
      Citations:    
    265. Pustina D, Doucet G, Skidmore C, Sperling M, Tracy J. Contralateral interictal spikes are related to tapetum damage in left temporal lobe epilepsy. Epilepsia. 2014 Sep; 55(9):1406-14. PMID: 25041176.
      Citations:    
    266. Sperling MR, Rosenow F, Faught E, Hebert D, Doty P, Isoj?rvi J. Efficacy of lacosamide by focal seizure subtype. Epilepsy Res. 2014 Oct; 108(8):1392-8. PMID: 25082395.
      Citations:    
    267. Doucet GE, Sharan A, Pustina D, Skidmore C, Sperling MR, Tracy JI. Early and late age of seizure onset have a differential impact on brain resting-state organization in temporal lobe epilepsy. Brain Topogr. 2015 Jan; 28(1):113-26. PMID: 24881003.
      Citations:    
    268. Mathern G, Nehlig A, Sperling M. Cannabidiol and medical marijuana for the treatment of epilepsy. Epilepsia. 2014 Jun; 55(6):781-2. PMID: 24854631.
      Citations:    
    269. Henney HR, Sperling MR, Rabinowicz AL, Bream G, Carrazana EJ. Assessment of pharmacokinetics and tolerability of intranasal diazepam relative to rectal gel in healthy adults. Epilepsy Res. 2014 Sep; 108(7):1204-11. PMID: 24934774.
      Citations:    
    270. Nei M, Ngo L, Sirven JI, Sperling MR. Ketogenic diet in adolescents and adults with epilepsy. Seizure. 2014 Jun; 23(6):439-42. PMID: 24675110.
      Citations:    
    271. Doucet GE, Skidmore C, Evans J, Sharan A, Sperling MR, Pustina D, Tracy JI. Temporal lobe epilepsy and surgery selectively alter the dorsal, not the ventral, default-mode network. Front Neurol. 2014; 5:23. PMID: 24653713.
      Citations:    
    272. Misra A, Burke JF, Ramayya AG, Jacobs J, Sperling MR, Moxon KA, Kahana MJ, Evans JJ, Sharan AD. Methods for implantation of micro-wire bundles and optimization of single/multi-unit recordings from human mesial temporal lobe. J Neural Eng. 2014 Apr; 11(2):026013. PMID: 24608589.
      Citations:    
    273. Geller AS, Burke JF, Sperling MR, Sharan AD, Litt B, Baltuch GH, Lucas TH, Kahana MJ. Eye closure causes widespread low-frequency power increase and focal gamma attenuation in the human electrocorticogram. Clin Neurophysiol. 2014 Sep; 125(9):1764-73. PMID: 24631141.
      Citations:    
    274. Hamid H, Blackmon K, Cong X, Dziura J, Atlas LY, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Devinsky O. Mood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery. Neurology. 2014 Mar 11; 82(10):887-94. PMID: 24489129.
      Citations:    
    275. Brown FC, Westerveld M, Langfitt JT, Hamberger M, Hamid H, Shinnar S, Sperling MR, Devinsky O, Barr W, Tracy J, Masur D, Bazil CW, Spencer SS. Influence of anxiety on memory performance in temporal lobe epilepsy. Epilepsy Behav. 2014 Feb; 31:19-24. PMID: 24291525.
      Citations:    
    276. Asadi-Pooya AA, Emami Y, Emami M, Sperling MR. Prolonged psychogenic nonepileptic seizures or pseudostatus. Epilepsy Behav. 2014 Feb; 31:304-6. PMID: 24262782.
      Citations:    
    277. Biton V, Berkovic SF, Abou-Khalil B, Sperling MR, Johnson ME, Lu S. Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double-blind, placebo-controlled trial. Epilepsia. 2014 Jan; 55(1):57-66. PMID: 24446953.
      Citations:    
    278. Lopinto-Khoury C, Sperling MR. Autoimmune status epilepticus. Curr Treat Options Neurol. 2013 Oct; 15(5):545-56. PMID: 23852708.
      Citations:    
    279. Doucet GE, Skidmore C, Sharan AD, Sperling MR, Tracy JI. Functional connectivity abnormalities vary by amygdala subdivision and are associated with psychiatric symptoms in unilateral temporal epilepsy. Brain Cogn. 2013 Nov; 83(2):171-82. PMID: 24036129.
      Citations:    
    280. Kasperaviciute D, Catarino CB, Matarin M, Leu C, Novy J, Tostevin A, Leal B, Hessel EV, Hallmann K, Hildebrand MS, Dahl HH, Ryten M, Trabzuni D, Ramasamy A, Alhusaini S, Doherty CP, Dorn T, Hansen J, Kr?mer G, Steinhoff BJ, Zumsteg D, Duncan S, K?lvi?inen RK, Eriksson KJ, Kantanen AM, Pandolfo M, Gruber-Sedlmayr U, Schlachter K, Reinthaler EM, Stogmann E, Zimprich F, Th??tre E, Smith C, O'Brien TJ, Meng Tan K, Petrovski S, Robbiano A, Paravidino R, Zara F, Striano P, Sperling MR, Buono RJ, Hakonarson H, Chaves J, Costa PP, Silva BM, da Silva AM, de Graan PN, Koeleman BP, Becker A, Schoch S, von Lehe M, Reif PS, Rosenow F, Becker F, Weber Y, Lerche H, R?ssler K, Buchfelder M, Hamer HM, Kobow K, Coras R, Blumcke I, Scheffer IE, Berkovic SF, Weale ME, Delanty N, Depondt C, Cavalleri GL, Kunz WS, Sisodiya SM. Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. Brain. 2013 Oct; 136(Pt 10):3140-50. PMID: 24014518.
      Citations:    
    281. Burneo JG, Sirven JI, Kiesel LW, Vecht CJ, Jehi L, Chung SS, Uhm J, Politsky JM, Chang EF, Husain AM, Tatum WO, Meador KJ, Noe K, Hesdorffer DC, Herman ST, Wiebe S, Engel J, Schrader S, Parko KL, Dichter MA, Kwan P, Kossoff E, Sperling MR. Managing common complex symptomatic epilepsies: tumors and trauma: american epilepsy society - 2012 annual course summary. Epilepsy Curr. 2013 Sep; 13(5):232-5. PMID: 24348117.
      Citations:    
    282. Asadi-Pooya AA, Razavizadegan SM, Abdi-Ardekani A, Sperling MR. Adjunctive use of verapamil in patients with refractory temporal lobe epilepsy: a pilot study. Epilepsy Behav. 2013 Oct; 29(1):150-4. PMID: 23973639.
      Citations:    
    283. Jacobs J, Weidemann CT, Miller JF, Solway A, Burke JF, Wei XX, Suthana N, Sperling MR, Sharan AD, Fried I, Kahana MJ. Direct recordings of grid-like neuronal activity in human spatial navigation. Nat Neurosci. 2013 Sep; 16(9):1188-90. PMID: 23912946.
      Citations:    
    284. Urtecho J, Snapp M, Sperling M, Maltenfort M, Vibbert M, Athar MK, McBride W, Moussouttas M, Bell R, Jallo J, Rincon F. Hospital mortality in primary admissions of septic patients with status epilepticus in the United States*. Crit Care Med. 2013 Aug; 41(8):1853-62. PMID: 23782964.
      Citations:    
    285. Rodriguez Merzagora A, Coffey TJ, Sperling MR, Sharan A, Litt B, Baltuch G, Jacobs J. Repeated stimuli elicit diminished high-gamma electrocorticographic responses. Neuroimage. 2014 Jan 15; 85 Pt 2:844-52. PMID: 23867555.
      Citations:    
    286. Burke JF, Long NM, Zaghloul KA, Sharan AD, Sperling MR, Kahana MJ. Human intracranial high-frequency activity maps episodic memory formation in space and time. Neuroimage. 2014 Jan 15; 85 Pt 2:834-43. PMID: 23827329.
      Citations:    
    287. Sperling MR. Commentary on Standardized computer-based organized reporting of EEG: SCORE. Epilepsia. 2013 Jun; 54(6):1135-6. PMID: 23731402.
      Citations:    
    288. Riviello JJ, Claassen J, LaRoche SM, Sperling MR, Alldredge B, Bleck TP, Glauser T, Shutter L, Treiman DM, Vespa PM, Bell R, Brophy GM. Treatment of status epilepticus: an international survey of experts. Neurocrit Care. 2013 Apr; 18(2):193-200. PMID: 23097138.
      Citations:    
    289. Hesdorffer DC, French JA, Posner K, DiVentura B, Pollard JR, Sperling MR, Harden CL, Krauss GL, Kanner AM. Suicidal ideation and behavior screening in intractable focal epilepsy eligible for drug trials. Epilepsia. 2013 May; 54(5):879-87. PMID: 23448169.
      Citations:    
    290. van Gerven MA, Maris E, Sperling M, Sharan A, Litt B, Anderson C, Baltuch G, Jacobs J. Decoding the memorization of individual stimuli with direct human brain recordings. Neuroimage. 2013 Apr 15; 70:223-32. PMID: 23298746.
      Citations:    
    291. Burke JF, Zaghloul KA, Jacobs J, Williams RB, Sperling MR, Sharan AD, Kahana MJ. Synchronous and asynchronous theta and gamma activity during episodic memory formation. J Neurosci. 2013 Jan 02; 33(1):292-304. PMID: 23283342.
      Citations:    
    292. Doucet G, Osipowicz K, Sharan A, Sperling MR, Tracy JI. Hippocampal functional connectivity patterns during spatial working memory differ in right versus left temporal lobe epilepsy. Brain Connect. 2013; 3(4):398-406. PMID: 23705755.
      Citations:    
    293. Asadi-Pooya AA, Emami M, Sperling MR. A clinical study of syndromes of idiopathic (genetic) generalized epilepsy. J Neurol Sci. 2013 Jan 15; 324(1-2):113-7. PMID: 23149265.
      Citations:    
    294. Wu C, Evans JJ, Skidmore C, Sperling MR, Sharan AD. Impedance variations over time for a closed-loop neurostimulation device: early experience with chronically implanted electrodes. Neuromodulation. 2013 Jan-Feb; 16(1):46-50; discussion 50. PMID: 23136991.
      Citations:    
    295. Wu C, Sperling MR, Falowski SM, Chitale AV, Werner-Wasik M, Evans JJ, Andrews DW, Sharan AD. Radiosurgery for the treatment of dominant hemisphere periventricular heterotopia and intractable epilepsy in a series of three patients. Epilepsy Behav Case Rep. 2013; 1:1-6. PMID: 25688044.
      Citations:    
    296. Tracy JI, Hernandez RN, Mayekar S, Osipowicz K, Corbett B, Pascua M, Sperling MR, Sharan AD. The functional anatomy of non-verbal (pitch memory) function in left and right anterior temporal lobectomy patients. Clin Neurol Neurosurg. 2013 Jul; 115(7):934-43. PMID: 23031747.
      Citations:    
    297. Tracy JI, Osipowicz K, Spechler P, Sharan A, Skidmore C, Doucet G, Sperling MR. Functional connectivity evidence of cortico-cortico inhibition in temporal lobe epilepsy. Hum Brain Mapp. 2014 Jan; 35(1):353-66. PMID: 22987774.
      Citations:    
    298. Tracy JI, Osipowicz K, Godofsky S, Shah A, Khan W, Sharan A, Sperling MR. An investigation of implicit memory through left temporal lobectomy for epilepsy. Neurobiol Learn Mem. 2012 Oct; 98(3):272-83. PMID: 22981890.
      Citations:    
    299. Wang SP, Mintzer S, Skidmore CT, Zhan T, Stuckert E, Nei M, Sperling MR. Seizure recurrence and remission after switching antiepileptic drugs. Epilepsia. 2013 Jan; 54(1):187-93. PMID: 22931161.
      Citations:    
    300. Morton NW, Kahana MJ, Rosenberg EA, Baltuch GH, Litt B, Sharan AD, Sperling MR, Polyn SM. Category-specific neural oscillations predict recall organization during memory search. Cereb Cortex. 2013 Oct; 23(10):2407-22. PMID: 22875859.
      Citations:    
    301. Brophy GM, Bell R, Claassen J, Alldredge B, Bleck TP, Glauser T, Laroche SM, Riviello JJ, Shutter L, Sperling MR, Treiman DM, Vespa PM. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care. 2012 Aug; 17(1):3-23. PMID: 22528274.
      Citations:    
    302. Holtkamp M, Sharan A, Sperling MR. Intracranial EEG in predicting surgical outcome in frontal lobe epilepsy. Epilepsia. 2012 Oct; 53(10):1739-45. PMID: 22813424.
      Citations:    
    303. Manning JR, Sperling MR, Sharan A, Rosenberg EA, Kahana MJ. Spontaneously reactivated patterns in frontal and temporal lobe predict semantic clustering during memory search. J Neurosci. 2012 Jun 27; 32(26):8871-8. PMID: 22745488.
      Citations:    
    304. Nei M, Sperling MR, Mintzer S, Ho RT. Long-term cardiac rhythm and repolarization abnormalities in refractory focal and generalized epilepsy. Epilepsia. 2012 Aug; 53(8):e137-40. PMID: 22709423.
      Citations:    
    305. Mintzer S, Skidmore CT, Sperling MR. B-vitamin deficiency in patients treated with antiepileptic drugs. Epilepsy Behav. 2012 Jul; 24(3):341-4. PMID: 22658435.
      Citations:    
    306. Herzog AG, Fowler KM, Smithson SD, Kalayjian LA, Heck CN, Sperling MR, Liporace JD, Harden CL, Dworetzky BA, Pennell PB, Massaro JM. Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial. Neurology. 2012 Jun 12; 78(24):1959-66. PMID: 22649214.
      Citations:    
    307. Nguyen QD, Schachar RA, Nduaka CI, Sperling M, Basile AS, Klamerus KJ, Chi-Burris K, Yan E, Paggiarino DA, Rosenblatt I, Khan A, Aitchison R, Erlich SS. Phase 1 dose-escalation study of a siRNA targeting the RTP801 gene in age-related macular degeneration patients. Eye (Lond). 2012 Aug; 26(8):1099-105. PMID: 22627477.
      Citations:    
    308. Asadi-Pooya AA, Emami M, Sperling MR. Age of onset in idiopathic (genetic) generalized epilepsies: clinical and EEG findings in various age groups. Seizure. 2012 Jul; 21(6):417-21. PMID: 22560254.
      Citations:    
    309. Penn DL, Wu C, Skidmore C, Sperling MR, Sharan AD. Twiddler's syndrome in a patient with epilepsy treated with deep brain stimulation. Epilepsia. 2012 Jul; 53(7):e119-21. PMID: 22554113.
      Citations:    
    310. Doucet G, Osipowicz K, Sharan A, Sperling MR, Tracy JI. Extratemporal functional connectivity impairments at rest are related to memory performance in mesial temporal epilepsy. Hum Brain Mapp. 2013 Sep; 34(9):2202-16. PMID: 22505284.
      Citations:    
    311. Engel J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012 Mar 07; 307(9):922-30. PMID: 22396514.
      Citations:    
    312. LoPinto-Khoury C, Sperling MR, Skidmore C, Nei M, Evans J, Sharan A, Mintzer S. Surgical outcome in PET-positive, MRI-negative patients with temporal lobe epilepsy. Epilepsia. 2012 Feb; 53(2):342-8. PMID: 22192050.
      Citations:    
    313. Krauss GL, Sperling MR. Treating patients with medically resistant epilepsy. Neurol Clin Pract. 2011 Dec; 1(1):14-23. PMID: 23634355.
      Citations:    
    314. Mintzer S, Skidmore CT, Rankin SJ, Chervoneva I, Pequinot E, Capuzzi DM, Sperling MR. Conversion from enzyme-inducing antiepileptic drugs to topiramate: effects on lipids and C-reactive protein. Epilepsy Res. 2012 Jan; 98(1):88-93. PMID: 22119637.
      Citations:    
    315. Hamid H, Liu H, Cong X, Devinsky O, Berg AT, Vickrey BG, Sperling MR, Shinnar S, Langfitt JT, Walczak TS, Barr WB, Dziura J, Bazil CW, Spencer SS. Long-term association between seizure outcome and depression after resective epilepsy surgery. Neurology. 2011 Nov 29; 77(22):1972-6. PMID: 22094480.
      Citations:    
    316. Herzog AG, Fowler KM, Sperling MR, Liporace JD, Kalayjian LA, Heck CN, Krauss GL, Dworetzky BA, Pennell PB. Variation of seizure frequency with ovulatory status of menstrual cycles. Epilepsia. 2011 Oct; 52(10):1843-8. PMID: 21756250.
      Citations:    
    317. Zarroli K, Tracy JI, Nei M, Sharan A, Sperling MR. Employment after anterior temporal lobectomy. Epilepsia. 2011 May; 52(5):925-31. PMID: 21561447.
      Citations:    
    318. Hamid H, Devinsky O, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Spencer SS. Suicide outcomes after resective epilepsy surgery. Epilepsy Behav. 2011 Mar; 20(3):462-4. PMID: 21334984.
      Citations:    
    319. Sperling MR, Korczyn AD. Editorial comments. J Neural Transm (Vienna). 2011 Feb; 118(2):181. PMID: 21350942.
      Citations:    
    320. Asadi-Pooya AA, Sperling MR. Depression and anxiety in patients with epilepsy, with or without other chronic disorders. Iran Red Crescent Med J. 2011 Feb; 13(2):112-6. PMID: 22737444.
      Citations:    
    321. Sperling MR. Special section: from the American Epilepsy Society 2009 Annual Course. Introduction. Epilepsy Behav. 2011 Feb; 20(2):155. PMID: 21262588.
      Citations:    
    322. Sharan A, Ooi YC, Langfitt J, Sperling MR. Intracarotid amobarbital procedure for epilepsy surgery. Epilepsy Behav. 2011 Feb; 20(2):209-13. PMID: 21190900.
      Citations:    
    323. Jenssen S, Roberts CM, Gracely EJ, Dlugos DJ, Sperling MR. Focal seizure propagation in the intracranial EEG. Epilepsy Res. 2011 Jan; 93(1):25-32. PMID: 21130604.
      Citations:    
    324. Chung S, Ben-Menachem E, Sperling MR, Rosenfeld W, Fountain NB, Benbadis S, Hebert D, Isoj?rvi J, Doty P. Examining the clinical utility of lacosamide: pooled analyses of three phase II/III clinical trials. CNS Drugs. 2010 Dec; 24(12):1041-54. PMID: 21090838.
      Citations:    
    325. Benbadis SR, Faught RE, Sirven J, Slater JD, Sperling MR, Hirsch LJ. The pervasive influence of conflicts of interest: a personal perspective. Neurology. 2010 Nov 30; 75(22):2045-6. PMID: 21158001.
      Citations:    
    326. Murray RC, Powell D, Curry JM, Sperling MR, Evans JJ, Spiegel JR. Epileptic laryngospasm presenting as a primary sleep disturbance. Arch Otolaryngol Head Neck Surg. 2010 Oct; 136(10):1025-7. PMID: 20956752.
      Citations:    
    327. Buckingham SE, Chervoneva I, Sharan A, Zangaladze A, Mintzer S, Skidmore C, Nei M, Evans J, Pequignot E, Sperling MR. Latency to first seizure after temporal lobectomy predicts long-term outcome. Epilepsia. 2010 Oct; 51(10):1987-93. PMID: 21069902.
      Citations:    
    328. Engel J, McDermott MP, Wiebe S, Langfitt JT, Erba G, Gardiner I, Stern J, Dewar S, Sperling MR, Jacobs M, Kieburtz K. Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy. Epilepsia. 2010 Oct; 51(10):1978-86. PMID: 20550556.
      Citations:    
    329. Osipowicz K, Rickards T, Shah A, Sharan A, Sperling M, Kahn W, Tracy J. A test of the role of the medial temporal lobe in single-word decoding. Neuroimage. 2011 Jan 15; 54(2):1455-64. PMID: 20884357.
      Citations:    
    330. Benbadis SR, Faught RE, Hirsch L, Sperling M, Slater J, Sirven J. Open letter (and invitation) to the pharmaceutical industry: "no, we cannot just present your slide deck ?". Epilepsy Behav. 2010 Nov; 19(3):544-5. PMID: 20833110.
      Citations:    
    331. Helbig KL, Bernhardt BA, Conway LJ, Valverde KD, Helbig I, Sperling MR. Genetic risk perception and reproductive decision making among people with epilepsy. Epilepsia. 2010 Sep; 51(9):1874-7. PMID: 20163441.
      Citations:    
    332. Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, Oommen K, Osorio I, Nazzaro J, Labar D, Kaplitt M, Sperling M, Sandok E, Neal J, Handforth A, Stern J, DeSalles A, Chung S, Shetter A, Bergen D, Bakay R, Henderson J, French J, Baltuch G, Rosenfeld W, Youkilis A, Marks W, Garcia P, Barbaro N, Fountain N, Bazil C, Goodman R, McKhann G, Babu Krishnamurthy K, Papavassiliou S, Epstein C, Pollard J, Tonder L, Grebin J, Coffey R, Graves N. Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia. 2010 May; 51(5):899-908. PMID: 20331461.
      Citations:    
    333. Chung S, Sperling MR, Biton V, Krauss G, Hebert D, Rudd GD, Doty P. Lacosamide as adjunctive therapy for partial-onset seizures: a randomized controlled trial. Epilepsia. 2010 Jun; 51(6):958-67. PMID: 20132285.
      Citations:    
    334. Zangaladze A, Asadi-Pooya AA, Ashkenazi A, Sperling MR. Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation. Epilepsy Behav. 2010 Feb; 17(2):293-5. PMID: 20071244.
      Citations:    
    335. Asbury AK, Sperling MR, Aguirre GK, Liu GT. Selected contributions to neurology by Philadelphia neurologists since 1980. Rev Neurol Dis. 2010; 7(4):140-9. PMID: 21206430.
      Citations:    
    336. Sperling MR, Greenspan A, Cramer JA, Kwan P, K?lvi?inen R, Halford JJ, Schmitt J, Yuen E, Cook T, Haas M, Novak G. Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials. Epilepsia. 2010 Mar; 51(3):333-43. PMID: 19863578.
      Citations:    
    337. Asadi-Pooya AA, Sperling MR. Clinical features of sudden unexpected death in epilepsy. J Clin Neurophysiol. 2009 Oct; 26(5):297-301. PMID: 19713869.
      Citations:    
    338. Kwan P, Sperling MR. Refractory seizures: try additional antiepileptic drugs (after two have failed) or go directly to early surgery evaluation? Epilepsia. 2009 Sep; 50 Suppl 8:57-62. PMID: 19702735.
      Citations:    
    339. Mechanic-Hamilton D, Korczykowski M, Yushkevich PA, Lawler K, Pluta J, Glynn S, Tracy JI, Wolf RL, Sperling MR, French JA, Detre JA. Hippocampal volumetry and functional MRI of memory in temporal lobe epilepsy. Epilepsy Behav. 2009 Sep; 16(1):128-38. PMID: 19674939.
      Citations:    
    340. Mintzer S, Skidmore CT, Abidin CJ, Morales MC, Chervoneva I, Capuzzi DM, Sperling MR. Effects of antiepileptic drugs on lipids, homocysteine, and C-reactive protein. Ann Neurol. 2009 Apr; 65(4):448-56. PMID: 19296463.
      Citations:    
    341. Tracy JI, Waldron B, Glosser D, Sharan A, Mintzer S, Zangaladze A, Skidmore C, Siddiqui I, Caris E, Sperling MR. Hemispheric lateralization and language skill coherence in temporal lobe epilepsy. Cortex. 2009 Nov-Dec; 45(10):1178-89. PMID: 19286172.
      Citations:    
    342. Bower CM, Hays RD, Devinsky O, Spencer SS, Sperling MR, Haut S, Vassar S, Vickrey BG. Expectations prior to epilepsy surgery: an exploratory comparison of men and women. Seizure. 2009 Apr; 18(3):228-31. PMID: 18926728.
      Citations:    
    343. Asadi-Pooya AA, Nei M, Sharan AD, Mintzer S, Zangaladze A, Evans JG, Skidmore C, Sperling MR. Antiepileptic drugs and relapse after epilepsy surgery. Epileptic Disord. 2008 Sep; 10(3):193-8. PMID: 18782687.
      Citations:    
    344. Bujarski K, Sperling MR. Post-ictal hyperfamiliarity syndrome in focal epilepsy. Epilepsy Behav. 2008 Oct; 13(3):567-9. PMID: 18588998.
      Citations:    
    345. Asadi-Pooya AA, Sharan A, Nei M, Sperling MR. Corpus callosotomy. Epilepsy Behav. 2008 Aug; 13(2):271-8. PMID: 18539083.
      Citations:    
    346. Asadi-Pooya AA, Mintzer S, Sperling MR. Nutritional supplements, foods, and epilepsy: is there a relationship? Epilepsia. 2008 Nov; 49(11):1819-27. PMID: 18503556.
      Citations:    
    347. Zangaladze A, Nei M, Liporace JD, Sperling MR. Characteristics and clinical significance of subclinical seizures. Epilepsia. 2008 Dec; 49(12):2016-21. PMID: 18503561.
      Citations:    
    348. Matheny ME, Sequist TD, Seger AC, Fiskio JM, Sperling M, Bugbee D, Bates DW, Gandhi TK. A randomized trial of electronic clinical reminders to improve medication laboratory monitoring. J Am Med Inform Assoc. 2008 Jul-Aug; 15(4):424-9. PMID: 18436905.
      Citations:    
    349. Mintzer S, Sperling MR. When should a resection sparing mesial structures be considered for temporal lobe epilepsy? Epilepsy Behav. 2008 Jul; 13(1):7-11. PMID: 18359666.
      Citations:    
    350. Chandrasekar T, Sharan AD, Sperling MR. Postoperative auras and the risk of recurrent seizures. Epilepsy Res. 2008 Feb; 78(2-3):195-200. PMID: 18221856.
      Citations:    
    351. Sperling MR, Nei M, Zangaladze A, Sharan AD, Mintzer SE, Skidmore C, Evans JG, Schilling CA, Asadi-Pooya AA. Prognosis after late relapse following epilepsy surgery. Epilepsy Res. 2008 Jan; 78(1):77-81. PMID: 18077135.
      Citations:    
    352. Sperling MR, Schilling CA, Glosser D, Tracy JI, Asadi-Pooya AA. Self-perception of seizure precipitants and their relation to anxiety level, depression, and health locus of control in epilepsy. Seizure. 2008 Jun; 17(4):302-7. PMID: 17977026.
      Citations:    
    353. Asadi-Pooya AA, Sperling MR. Strategies for surgical treatment of epilepsies in developing countries. Epilepsia. 2008 Mar; 49(3):381-5. PMID: 17941843.
      Citations:    
    354. Asadi-Pooya AA, Sperling MR. Do foods precipitate seizures? A cross-cultural comparison. Epilepsy Behav. 2007 Nov; 11(3):450-3. PMID: 17905669.
      Citations:    
    355. Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Haut S, Langfitt JT, Walczak TS, Devinsky O. Health-related quality of life over time since resective epilepsy surgery. Ann Neurol. 2007 Oct; 62(4):327-34. PMID: 17567854.
      Citations:    
    356. Asadi-Pooya AA, Schilling CA, Glosser D, Tracy JI, Sperling MR. Health locus of control in patients with epilepsy and its relationship to anxiety, depression, and seizure control. Epilepsy Behav. 2007 Nov; 11(3):347-50. PMID: 17904913.
      Citations:    
    357. Zangaladze A, Sharan A, Evans J, Wyeth DH, Wyeth EG, Tracy JI, Chervoneva I, Sperling MR. The effectiveness of low-frequency stimulation for mapping cortical function. Epilepsia. 2008 Mar; 49(3):481-7. PMID: 17868054.
      Citations:    
    358. Tracy JI, Lippincott C, Mahmood T, Waldron B, Kanauss K, Glosser D, Sperling MR. Are depression and cognitive performance related in temporal lobe epilepsy? Epilepsia. 2007 Dec; 48(12):2327-35. PMID: 17697111.
      Citations:    
    359. So NK, Sperling MR. Ictal asystole and SUDEP. Neurology. 2007 Jul 31; 69(5):423-4. PMID: 17664399.
      Citations:    
    360. Chin PS, Berg AT, Spencer SS, Sperling MR, Haut SR, Langfitt JT, Bazil CW, Walczak TS, Pacia SV, Vickrey BG. Employment outcomes following resective epilepsy surgery. Epilepsia. 2007 Dec; 48(12):2253-7. PMID: 17645537.
      Citations:    
    361. Harden CL, Maroof DA, Nikolov B, Fowler K, Sperling M, Liporace J, Pennell P, Labar D, Herzog A. The effect of seizure severity on quality of life in epilepsy. Epilepsy Behav. 2007 Sep; 11(2):208-11. PMID: 17604229.
      Citations:    
    362. Langfitt JT, Westerveld M, Hamberger MJ, Walczak TS, Cicchetti DV, Berg AT, Vickrey BG, Barr WB, Sperling MR, Masur D, Spencer SS. Worsening of quality of life after epilepsy surgery: effect of seizures and memory decline. Neurology. 2007 Jun 05; 68(23):1988-94. PMID: 17548548.
      Citations:    
    363. Langfitt JT, Holloway RG, McDermott MP, Messing S, Sarosky K, Berg AT, Spencer SS, Vickrey BG, Sperling MR, Bazil CW, Shinnar S. Health care costs decline after successful epilepsy surgery. Neurology. 2007 Apr 17; 68(16):1290-8. PMID: 17438219.
      Citations:    
    364. Asadi-Pooya AA, Sperling MR. Potentiation of anti-epileptic drugs effectiveness by pyronaridine in refractory epilepsy. Med Hypotheses. 2007; 69(3):560-3. PMID: 17368747.
      Citations:    
    365. Mitre E, Talaat KR, Sperling MR, Nash TE. Methotrexate as a corticosteroid-sparing agent in complicated neurocysticercosis. Clin Infect Dis. 2007 Feb 15; 44(4):549-53. PMID: 17243058.
      Citations:    
    366. Jenssen S, Sperling MR, Tracy JI, Nei M, Joyce L, David G, O'Connor M. Corpus callosotomy in refractory idiopathic generalized epilepsy. Seizure. 2006 Dec; 15(8):621-9. PMID: 17067824.
      Citations:    
    367. Jenssen S, Gracely E, Mahmood T, Tracy JI, Sperling MR. Subjective somnolence relates mainly to depression among patients in a tertiary care epilepsy center. Epilepsy Behav. 2006 Dec; 9(4):632-5. PMID: 16996802.
      Citations:    
    368. Tracy JI, Dechant V, Sperling MR, Cho R, Glosser D. The association of mood with quality of life ratings in epilepsy. Neurology. 2007 Apr 03; 68(14):1101-7. PMID: 16988068.
      Citations:    
    369. Jenssen S, Gracely EJ, Sperling MR. How long do most seizures last? A systematic comparison of seizures recorded in the epilepsy monitoring unit. Epilepsia. 2006 Sep; 47(9):1499-503. PMID: 16981866.
      Citations:    
    370. Chin PS, Berg AT, Spencer SS, Lee ML, Shinnar S, Sperling MR, Langfitt JT, Walczak TS, Pacia SV, Bazil CW, Vassar S, Vickrey BG. Patient-perceived impact of resective epilepsy surgery. Neurology. 2006 Jun 27; 66(12):1882-7. PMID: 16801655.
      Citations:    
    371. Langfitt JT, Vickrey BG, McDermott MP, Messing S, Berg AT, Spencer SS, Sperling MR, Bazil CW, Shinnar S. Validity and responsiveness of generic preference-based HRQOL instruments in chronic epilepsy. Qual Life Res. 2006 Jun; 15(5):899-914. PMID: 16721649.
      Citations:    
    372. Sperling MR. EEG reading session. J Clin Neurophysiol. 2006 Jun; 23(3):230-7. PMID: 16751723.
      Citations:    
    373. Sperling MR, Ko J. Seizures and brain tumors. Semin Oncol. 2006 Jun; 33(3):333-41. PMID: 16769422.
      Citations:    
    374. Schwartz TH, Jeha L, Tanner A, Bingaman W, Sperling MR. Late seizures in patients initially seizure free after epilepsy surgery. Epilepsia. 2006 Mar; 47(3):567-73. PMID: 16529623.
      Citations:    
    375. Berg AT, Vickrey BG, Langfitt JT, Sperling MR, Shinnar S, Bazil C, Walczak T, Spencer SS. Reduction of AEDs in postsurgical patients who attain remission. Epilepsia. 2006 Jan; 47(1):64-71. PMID: 16417533.
      Citations:    
    376. Nei M, O'Connor M, Liporace J, Sperling MR. Refractory generalized seizures: response to corpus callosotomy and vagal nerve stimulation. Epilepsia. 2006 Jan; 47(1):115-22. PMID: 16417539.
      Citations:    
    377. Pillai J, Sperling MR. Interictal EEG and the diagnosis of epilepsy. Epilepsia. 2006; 47 Suppl 1:14-22. PMID: 17044820.
      Citations:    
    378. Jenssen S, Liporace J, Nei M, O'connor MJ, Sperling MR. Value of non-invasive testing when there are independent bitemporal seizures in the scalp EEG. Epilepsy Res. 2006 Feb; 68(2):115-22. PMID: 16386405.
      Citations:    
    379. Devinsky O, Barr WB, Vickrey BG, Berg AT, Bazil CW, Pacia SV, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Spencer SS. Changes in depression and anxiety after resective surgery for epilepsy. Neurology. 2005 Dec 13; 65(11):1744-9. PMID: 16344516.
      Citations:    
    380. Khoury JS, Winokur RS, Tracy JI, Sperling MR. Predicting seizure frequency after epilepsy surgery. Epilepsy Res. 2005 Dec; 67(3):89-99. PMID: 16256308.
      Citations:    
    381. Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Shinnar S, Langfitt JT, Walczak TS, Pacia SV. Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter study. Neurology. 2005 Sep 27; 65(6):912-8. PMID: 16186534.
      Citations:    
    382. Kulkarni K, Sperling MR, Intenzo C. Positron emission tomography in Dyke-Davidoff-Masson syndrome. Clin Nucl Med. 2005 Sep; 30(9):625-7. PMID: 16100487.
      Citations:    
    383. Lohoff FW, Ferraro TN, Dahl JP, Hildebrandt MA, Scattergood TM, O'Connor MJ, Sperling MR, Dlugos DJ, Berrettini WH, Buono RJ. Lack of association between variations in the brain-derived neurotrophic factor (BDNF) gene and temporal lobe epilepsy. Epilepsy Res. 2005 Aug-Sep; 66(1-3):59-62. PMID: 16105728.
      Citations:    
    384. Siegel AM, Cascino GD, Elger CE, Devinsky O, Laff R, Najjar S, Sperling MR, LoRusso G, Cossu M, Urbach H, Aronica E, Meyer FB, Scheithauer BW, Dubeau F, Andermann F. Adult-onset epilepsy in focal cortical dysplasia of Taylor type. Neurology. 2005 May 24; 64(10):1771-4. PMID: 15911808.
      Citations:    
    385. Paek SH, Audu PB, Sperling MR, Cho J, Andrews DW. Reevaluation of surgery for the treatment of brain metastases: review of 208 patients with single or multiple brain metastases treated at one institution with modern neurosurgical techniques. Neurosurgery. 2005 May; 56(5):1021-34; discussion 1021-34. PMID: 15854250.
      Citations:    
    386. Sperling MR, Harris A, Nei M, Liporace JD, O'Connor MJ. Mortality after epilepsy surgery. Epilepsia. 2005; 46 Suppl 11:49-53. PMID: 16393181.
      Citations:    
    387. Herzog AG, Harden CL, Liporace J, Pennell P, Schomer DL, Sperling M, Fowler K, Nikolov B, Shuman S, Newman M. Frequency of catamenial seizure exacerbation in women with localization-related epilepsy. Ann Neurol. 2004 Sep; 56(3):431-4. PMID: 15349872.
      Citations:    
    388. Del Vecchio N, Liporace J, Nei M, Sperling M, Tracy J. A dissociation between implicit and explicit verbal memory in left temporal lobe epilepsy. Epilepsia. 2004 Sep; 45(9):1124-33. PMID: 15329078.
      Citations:    
    389. Rabin ML, Narayan VM, Kimberg DY, Casasanto DJ, Glosser G, Tracy JI, French JA, Sperling MR, Detre JA. Functional MRI predicts post-surgical memory following temporal lobectomy. Brain. 2004 Oct; 127(Pt 10):2286-98. PMID: 15329352.
      Citations:    
    390. Nei M, Ho RT, Abou-Khalil BW, Drislane FW, Liporace J, Romeo A, Sperling MR. EEG and ECG in sudden unexplained death in epilepsy. Epilepsia. 2004 Apr; 45(4):338-45. PMID: 15030496.
      Citations:    
    391. Sperling MR. The consequences of uncontrolled epilepsy. CNS Spectr. 2004 Feb; 9(2):98-101, 106-9. PMID: 14999166.
      Citations:    
    392. Buono RJ, Lohoff FW, Sander T, Sperling MR, O'Connor MJ, Dlugos DJ, Ryan SG, Golden GT, Zhao H, Scattergood TM, Berrettini WH, Ferraro TN. Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility. Epilepsy Res. 2004 Feb; 58(2-3):175-83. PMID: 15120748.
      Citations:    
    393. Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Shinnar S, Langfitt JT, Walczak TS, Pacia SV, Ebrahimi N, Frobish D. Initial outcomes in the Multicenter Study of Epilepsy Surgery. Neurology. 2003 Dec 23; 61(12):1680-5. PMID: 14694029.
      Citations:    
    394. Berg AT, Vickrey BG, Langfitt JT, Sperling MR, Walczak TS, Shinnar S, Bazil CW, Pacia SV, Spencer SS. The multicenter study of epilepsy surgery: recruitment and selection for surgery. Epilepsia. 2003 Nov; 44(11):1425-33. PMID: 14636351.
      Citations:    
    395. Carran MA, Kohler CG, O'Connor MJ, Bilker WB, Sperling MR. Mania following temporal lobectomy. Neurology. 2003 Sep 23; 61(6):770-4. PMID: 14504319.
      Citations:    
    396. Sperling MR, Guina L. The necessity for sphenoidal electrodes in the presurgical evaluation of temporal lobe epilepsy: pro position. J Clin Neurophysiol. 2003 Sep-Oct; 20(5):299-304. PMID: 14701990.
      Citations:    
    397. Engel J, Wiebe S, French J, Sperling M, Williamson P, Spencer D, Gumnit R, Zahn C, Westbrook E, Enos B. Practice parameter: temporal lobe and localized neocortical resections for epilepsy. Epilepsia. 2003 Jun; 44(6):741-51. PMID: 12790886.
      Citations:    
    398. Engel J, Wiebe S, French J, Sperling M, Williamson P, Spencer D, Gumnit R, Zahn C, Westbrook E, Enos B. Practice parameter: temporal lobe and localized neocortical resections for epilepsy: report of the Quality Standards Subcommittee of the American Academy of Neurology, in association with the American Epilepsy Society and the American Association of Neurological Surgeons. Neurology. 2003 Feb 25; 60(4):538-47. PMID: 12601090.
      Citations:    
    399. Berg AT, Langfitt J, Shinnar S, Vickrey BG, Sperling MR, Walczak T, Bazil C, Pacia SV, Spencer SS. How long does it take for partial epilepsy to become intractable? Neurology. 2003 Jan 28; 60(2):186-90. PMID: 12552028.
      Citations:    
    400. Haut SR, Berg AT, Shinnar S, Cohen HW, Bazil CW, Sperling MR, Langfitt JT, Pacia SV, Walczak TS, Spencer SS. Interrater reliability among epilepsy centers: multicenter study of epilepsy surgery. Epilepsia. 2002 Nov; 43(11):1396-401. PMID: 12423391.
      Citations:    
    401. Sperling MR. More on the Timing and Meaning of FDG-PET Abnormalities in Partial Epilepsy. Epilepsy Curr. 2002 Nov; 2(6):188. PMID: 15309114.
      Citations:    
    402. Begley CE, Beghi E, Beran RG, Heaney D, Langfitt JT, Pachlatko C, Silfvenius H, Sperling MR, Wiebe S. ILAE Commission on the Burden of Epilepsy, Subcommission on the Economic Burden of Epilepsy: Final report 1998-2001. Epilepsia. 2002 Jun; 43(6):668-73. PMID: 12060034.
      Citations:    
    403. Banh HL, Burton ME, Sperling MR. Interpatient and intrapatient variability in phenytoin protein binding. Ther Drug Monit. 2002 Jun; 24(3):379-85. PMID: 12021629.
      Citations:    
    404. Sperling MR, Schnur JK. Temporal lobectomy. Arch Neurol. 2002 Mar; 59(3):482-4. PMID: 11890859.
      Citations:    
    405. Spencer SS, Schramm J, Wyler A, O'Connor M, Orbach D, Krauss G, Sperling M, Devinsky O, Elger C, Lesser R, Mulligan L, Westerveld M. Multiple subpial transection for intractable partial epilepsy: an international meta-analysis. Epilepsia. 2002 Feb; 43(2):141-5. PMID: 11903459.
      Citations:    
    406. Platt M, Sperling MR. A comparison of surgical and medical costs for refractory epilepsy. Epilepsia. 2002; 43 Suppl 4:25-31. PMID: 12059998.
      Citations:    
    407. Liporace J, Hucko D, Morrow R, Barolat G, Nei M, Schnur J, Sperling M. Vagal nerve stimulation: adjustments to reduce painful side effects. Neurology. 2001 Sep 11; 57(5):885-6. PMID: 11552021.
      Citations:    
    408. Sperling MR. Sudden Unexplained Death in Epilepsy. Epilepsy Curr. 2001 Sep; 1(1):21-23. PMID: 15309034.
      Citations:    
    409. Ma X, Liporace J, O'Connor MJ, Sperling MR. Neurosurgical treatment of medically intractable status epilepticus. Epilepsy Res. 2001 Jul; 46(1):33-8. PMID: 11395286.
      Citations:    
    410. Buono RJ, Ferraro TN, O'Connor MJ, Sperling MR, Ryan SG, Scattergood T, Mulholland N, Gilmore J, Lohoff FW, Berrettini WH. Lack of association between an interleukin 1 beta (IL-1beta) gene variation and refractory temporal lobe epilepsy. Epilepsia. 2001 Jun; 42(6):782-4. PMID: 11422336.
      Citations:    
    411. Kohler CG, Carran MA, Bilker W, O'Connor MJ, Sperling MR. Association of fear auras with mood and anxiety disorders after temporal lobectomy. Epilepsia. 2001 May; 42(5):674-81. PMID: 11380577.
      Citations:    
    412. Kohler CG, Moberg PJ, Gur RE, O'Connor MJ, Sperling MR, Doty RL. Olfactory dysfunction in schizophrenia and temporal lobe epilepsy. Neuropsychiatry Neuropsychol Behav Neurol. 2001 Apr-Jun; 14(2):83-8. PMID: 11417670.
      Citations:    
    413. Wieser HG, Blume WT, Fish D, Goldensohn E, Hufnagel A, King D, Sperling MR, L?ders H, Pedley TA. ILAE Commission Report. Proposal for a new classification of outcome with respect to epileptic seizures following epilepsy surgery. Epilepsia. 2001 Feb; 42(2):282-6. PMID: 11240604.
      Citations:    
    414. Sirven JI, Sperling M, Wingerchuk DM. Early versus late antiepileptic drug withdrawal for people with epilepsy in remission. Cochrane Database Syst Rev. 2001; (3):CD001902. PMID: 11687000.
      Citations:    
    415. Newberg AB, Alavi A, Berlin J, Mozley PD, O'Connor M, Sperling M. Ipsilateral and contralateral thalamic hypometabolism as a predictor of outcome after temporal lobectomy for seizures. J Nucl Med. 2000 Dec; 41(12):1964-8. PMID: 11138679.
      Citations:    
    416. Sirven JI, Malamut BL, O'Connor MJ, Sperling MR. Temporal lobectomy outcome in older versus younger adults. Neurology. 2000 Jun 13; 54(11):2166-70. PMID: 10851387.
      Citations:    
    417. Vickrey BG, Berg AT, Sperling MR, Shinnar S, Langfitt JT, Bazil CW, Walczak TS, Pacia S, Kim S, Spencer SS. Relationships between seizure severity and health-related quality of life in refractory localization-related epilepsy. Epilepsia. 2000 Jun; 41(6):760-4. PMID: 10840410.
      Citations:    
    418. Nei M, Ho RT, Sperling MR. EKG abnormalities during partial seizures in refractory epilepsy. Epilepsia. 2000 May; 41(5):542-8. PMID: 10802759.
      Citations:    
    419. Sirven JI, Sperling M, Naritoku D, Schachter S, Labar D, Holmes M, Wilensky A, Cibula J, Labiner DM, Bergen D, Ristanovic R, Harvey J, Dasheiff R, Morris GL, O'Donovan CA, Ojemann L, Scales D, Nadkarni M, Richards B, Sanchez JD. Vagus nerve stimulation therapy for epilepsy in older adults. Neurology. 2000 Mar 14; 54(5):1179-82. PMID: 10720294.
      Citations:    
    420. Berg AT, Vickrey BG, Sperling MR, Langfitt JT, Bazil CW, Shinnar S, Walczak TS, Pacia S, Spencer SS. Driving in adults with refractory localization-related epilepsy. Multi-Center Study of Epilepsy Surgery. Neurology. 2000 Feb 08; 54(3):625-30. PMID: 10680794.
      Citations:    
    421. Buono RJ, Ferraro TN, O'Connor MJ, Sperling MR, Abbey M, Finanger E, Lohoff F, Mulholland N, Berrettini WH. Lack of association between temporal lobe epilepsy and a novel polymorphism in the alpha 2 subunit gene (ATP1A2) of the sodium potassium transporting ATPase. Am J Med Genet. 2000 Feb 07; 96(1):79-83. PMID: 10686557.
      Citations:    
    422. Dlugos DJ, Sperling MR. Propagation of neocortical extratemporal seizures. Adv Neurol. 2000; 84:287-97. PMID: 11091873.
      Citations:    
    423. Glosser G, Zwil AS, Glosser DS, O'Connor MJ, Sperling MR. Psychiatric aspects of temporal lobe epilepsy before and after anterior temporal lobectomy. J Neurol Neurosurg Psychiatry. 2000 Jan; 68(1):53-8. PMID: 10601402.
      Citations:    
    424. Carran MA, Kohler CG, O'Connor MJ, Cloud B, Sperling MR. Marital status after epilepsy surgery. Epilepsia. 1999 Dec; 40(12):1755-60. PMID: 10612340.
      Citations:    
    425. Sirven J, Whedon B, Caplan D, Liporace J, Glosser D, O'Dwyer J, Sperling MR. The ketogenic diet for intractable epilepsy in adults: preliminary results. Epilepsia. 1999 Dec; 40(12):1721-6. PMID: 10612335.
      Citations:    
    426. Sperling MR, Feldman H, Kinman J, Liporace JD, O'Connor MJ. Seizure control and mortality in epilepsy. Ann Neurol. 1999 Jul; 46(1):45-50. PMID: 10401779.
      Citations:    
    427. Dlugos DJ, Jaggi J, O'Connor WM, Ding XS, Reivich M, O'Connor MJ, Sperling MR. Hippocampal cell density and subcortical metabolism in temporal lobe epilepsy. Epilepsia. 1999 Apr; 40(4):408-13. PMID: 10219265.
      Citations:    
    428. Kohler C, Norstrand JA, Baltuch G, O'Connor MJ, Gur RE, French JA, Sperling MR. Depression in temporal lobe epilepsy before epilepsy surgery. Epilepsia. 1999 Mar; 40(3):336-40. PMID: 10080515.
      Citations:    
    429. Nei M, Lee JM, Shanker VL, Sperling MR. The EEG and prognosis in status epilepticus. Epilepsia. 1999 Feb; 40(2):157-63. PMID: 9952261.
      Citations:    
    430. Masukawa LM, Burdette LJ, McGonigle P, Wang H, O'Connor W, Sperling MR, O'Connor MJ, Uruno K. Physiological and anatomical correlates of the human dentate gyrus: consequences or causes of epilepsy. Adv Neurol. 1999; 79:781-94. PMID: 10514863.
      Citations:    
    431. Taylor T, Specker B, Robbins J, Sperling M, Ho M, Ain K, Bigos ST, Brierley J, Cooper D, Haugen B, Hay I, Hertzberg V, Klein I, Klein H, Ladenson P, Nishiyama R, Ross D, Sherman S, Maxon HR. Outcome after treatment of high-risk papillary and non-H?rthle-cell follicular thyroid carcinoma. Ann Intern Med. 1998 Oct 15; 129(8):622-7. PMID: 9786809.
      Citations:    
    432. Cooper DS, Specker B, Ho M, Sperling M, Ladenson PW, Ross DS, Ain KB, Bigos ST, Brierley JD, Haugen BR, Klein I, Robbins J, Sherman SI, Taylor T, Maxon HR. Thyrotropin suppression and disease progression in patients with differentiated thyroid cancer: results from the National Thyroid Cancer Treatment Cooperative Registry. Thyroid. 1998 Sep; 8(9):737-44. PMID: 9777742.
      Citations:    
    433. Sayre MR, Kaufmann KH, Chen IW, Sperling M, Sidman RD, Diercks DB, Liu T, Gibler WB. Measurement of cardiac troponin T is an effective method for predicting complications among emergency department patients with chest pain. Ann Emerg Med. 1998 May; 31(5):539-49. PMID: 9581136.
      Citations:    
    434. Schachter SC, Ito M, Wannamaker BB, Rak I, Ruggles K, Matsuo F, Wilner A, Jackel R, Gilliam F, Morris G, Skantz J, Sperling M, Buchhalter J, Drislane FW, Ives J, Schomer DL. Incidence of spikes and paroxysmal rhythmic events in overnight ambulatory computer-assisted EEGs of normal subjects: a multicenter study. J Clin Neurophysiol. 1998 May; 15(3):251-5. PMID: 9681563.
      Citations:    
    435. Swanson TH, Sperling MR, O'Connor MJ. Strong paired pulse depression of dentate granule cells in slices from patients with temporal lobe epilepsy. J Neural Transm (Vienna). 1998; 105(6-7):613-25. PMID: 9826106.
      Citations:    
    436. Sirven JI, Malamut BL, Liporace JD, O'Connor MJ, Sperling MR. Outcome after temporal lobectomy in bilateral temporal lobe epilepsy. Ann Neurol. 1997 Dec; 42(6):873-8. PMID: 9403479.
      Citations:    
    437. King JT, Sperling MR, Justice AC, O'Connor MJ. A cost-effectiveness analysis of anterior temporal lobectomy for intractable temporal lobe epilepsy. J Neurosurg. 1997 Jul; 87(1):20-8. PMID: 9202260.
      Citations:    
    438. Sperling MR, Bucurescu G, Kim B. Epilepsy management. Issues in medical and surgical treatment. Postgrad Med. 1997 Jul; 102(1):102-4, 109-12, 115-8 passim. PMID: 9224482.
      Citations:    
    439. Glosser G, Cole LC, French JA, Saykin AJ, Sperling MR. Predictors of intellectual performance in adults with intractable temporal lobe epilepsy. J Int Neuropsychol Soc. 1997 May; 3(3):252-9. PMID: 9161104.
      Citations:    
    440. Sirven JI, Liporace JD, French JA, O'Connor MJ, Sperling MR. Seizures in temporal lobe epilepsy: I. Reliability of scalp/sphenoidal ictal recording. Neurology. 1997 Apr; 48(4):1041-6. PMID: 9109897.
      Citations:    
    441. Masukawa LM, O'Connor WM, Burdette LJ, McGonigle P, Sperling MR, O'Connor MJ, Uruno K. Mossy fiber reorganization and its possible physiological consequences in the dentate gyrus of epileptic humans. Adv Neurol. 1997; 72:53-68. PMID: 8993684.
      Citations:    
    442. Sperling MR. Clinical challenges in invasive monitoring in epilepsy surgery. Epilepsia. 1997; 38 Suppl 4:S6-12. PMID: 9240235.
      Citations:    
    443. Swinehart JM, Sperling M, Phillips S, Kraus S, Gordon S, McCarty JM, Webster GF, Skinner R, Korey A, Orenberg EK. Intralesional fluorouracil/epinephrine injectable gel for treatment of condylomata acuminata. A phase 3 clinical study. Arch Dermatol. 1997 Jan; 133(1):67-73. PMID: 9006374.
      Citations:    
    444. Sperling MR, O'Connor MJ, Saykin AJ, Plummer C. Temporal lobectomy for refractory epilepsy. JAMA. 1996 Aug 14; 276(6):470-5. PMID: 8691555.
      Citations:    
    445. Detre JA, Alsop DC, Aguirre GK, Sperling MR. Coupling of cortical and thalamic ictal activity in human partial epilepsy: demonstration by functional magnetic resonance imaging. Epilepsia. 1996 Jul; 37(7):657-61. PMID: 8681898.
      Citations:    
    446. Sirven JI, Sperling MR, French JA, O'Connor MJ. Significance of simple partial seizures in temporal lobe epilepsy. Epilepsia. 1996 May; 37(5):450-4. PMID: 8617173.
      Citations:    
    447. O'Connor WM, Masukawa L, Freese A, Sperling MR, French JA, O'Connor MJ. Hippocampal cell distributions in temporal lobe epilepsy: a comparison between patients with and without an early risk factor. Epilepsia. 1996 May; 37(5):440-9. PMID: 8617172.
      Citations:    
    448. Wilson SB, Harner RN, Duffy FH, Tharp BR, Nuwer MR, Sperling MR. Spike detection. I. Correlation and reliability of human experts. Electroencephalogr Clin Neurophysiol. 1996 Mar; 98(3):186-98. PMID: 8631278.
      Citations:    
    449. Saykin AJ, Stafiniak P, Robinson LJ, Flannery KA, Gur RC, O'Connor MJ, Sperling MR. Language before and after temporal lobectomy: specificity of acute changes and relation to early risk factors. Epilepsia. 1995 Nov; 36(11):1071-7. PMID: 7588450.
      Citations:    
    450. Burgerman RS, Sperling MR, French JA, Saykin AJ, O'Connor MJ. Comparison of mesial versus neocortical onset temporal lobe seizures: neurodiagnostic findings and surgical outcome. Epilepsia. 1995 Jul; 36(7):662-70. PMID: 7555982.
      Citations:    
    451. Sperling MR, Alavi A, Reivich M, French JA, O'Connor MJ. False lateralization of temporal lobe epilepsy with FDG positron emission tomography. Epilepsia. 1995 Jul; 36(7):722-7. PMID: 7555991.
      Citations:    
    452. Legido A, Lago P, Chung HJ, Sperling M, Clancy RR. Serum prolactin in neonates with seizures. Epilepsia. 1995 Jul; 36(7):682-6. PMID: 7555985.
      Citations:    
    453. Tatum WO, Sperling MR, O'Connor MJ, Jacobstein JG. Interictal single-photon emission computed tomography in partial epilepsy. Accuracy in localization and prediction of outcome. J Neuroimaging. 1995 Jul; 5(3):142-4. PMID: 7626820.
      Citations:    
    454. Sperling MR, Saykin AJ, Roberts FD, French JA, O'Connor MJ. Occupational outcome after temporal lobectomy for refractory epilepsy. Neurology. 1995 May; 45(5):970-7. PMID: 7746417.
      Citations:    
    455. Laskowitz DT, Sperling MR, French JA, O'Connor MJ. The syndrome of frontal lobe epilepsy: characteristics and surgical management. Neurology. 1995 Apr; 45(4):780-7. PMID: 7723970.
      Citations:    
    456. Sperling MR, Skolnick BE. Cerebral blood flow during spike-wave discharges. Epilepsia. 1995 Feb; 36(2):156-63. PMID: 7821273.
      Citations:    
    457. Crino PB, Sater RA, Sperling M, Katsetos CD. Renal cell carcinomatous meningitis: pathologic and immunohistochemical features. Neurology. 1995 Jan; 45(1):189-91. PMID: 7529900.
      Citations:    
    458. Sperling MR, Saykin AJ, Glosser G, Moran M, French JA, Brooks M, O'Connor MJ. Predictors of outcome after anterior temporal lobectomy: the intracarotid amobarbital test. Neurology. 1994 Dec; 44(12):2325-30. PMID: 7991120.
      Citations:    
    459. Manno EM, Sperling MR, Ding X, Jaggi J, Alavi A, O'Connor MJ, Reivich M. Predictors of outcome after anterior temporal lobectomy: positron emission tomography. Neurology. 1994 Dec; 44(12):2331-6. PMID: 7991121.
      Citations:    
    460. Liporace JD, Sperling MR, Dichter MA. Absence seizures and carbamazepine in adults. Epilepsia. 1994 Sep-Oct; 35(5):1026-8. PMID: 7925146.
      Citations:    
    461. Morrell MJ, Sperling MR, Stecker M, Dichter MA. Sexual dysfunction in partial epilepsy: a deficit in physiologic sexual arousal. Neurology. 1994 Feb; 44(2):243-7. PMID: 8309566.
      Citations:    
    462. Adusumalli VE, Wichmann JK, Kucharczyk N, Kamin M, Sofia RD, French J, Sperling M, Bourgeois B, Devinsky O, Dreifuss FE, et al. Drug concentrations in human brain tissue samples from epileptic patients treated with felbamate. Drug Metab Dispos. 1994 Jan-Feb; 22(1):168-70. PMID: 8149879.
      Citations:    
    463. Sperling MR. Neuroimaging in epilepsy: recent developments in MR imaging, positron-emission tomography, and single-photon emission tomography. Neurol Clin. 1993 Nov; 11(4):883-903. PMID: 8272037.
      Citations:    
    464. O'Rourke DM, Saykin AJ, Gilhool JJ, Harley R, O'Connor MJ, Sperling MR. Unilateral hemispheric memory and hippocampal neuronal density in temporal lobe epilepsy. Neurosurgery. 1993 Apr; 32(4):574-80; discussion 580-1. PMID: 8474648.
      Citations:    
    465. Brooks ML, O'Connor MJ, Sperling MR, Mayer DP. Magnetic resonance imaging in localization of EEG depth electrodes for seizure monitoring. Epilepsia. 1992 Sep-Oct; 33(5):888-91. PMID: 1396431.
      Citations:    
    466. Masukawa LM, Uruno K, Sperling M, O'Connor MJ, Burdette LJ. The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patients. Brain Res. 1992 May 01; 579(1):119-27. PMID: 1623399.
      Citations:    
    467. Sperling MR, O'Connor MJ, Saykin AJ, Phillips CA, Morrell MJ, Bridgman PA, French JA, Gonatas N. A noninvasive protocol for anterior temporal lobectomy. Neurology. 1992 Feb; 42(2):416-22. PMID: 1736176.
      Citations:    
    468. Epstein MA, Sperling MR, O'Connor MJ. Cardiac rhythm during temporal lobe seizures. Neurology. 1992 Jan; 42(1):50-3. PMID: 1734323.
      Citations:    
    469. Morrell MJ, Phillips CA, O'Connor MJ, Sperling MR. Speech during partial seizures: intracranial EEG correlates. Epilepsia. 1991 Nov-Dec; 32(6):886-9. PMID: 1743161.
      Citations:    
    470. Tatum WO, Sperling MR, Jacobstein JG. Epileptic palatal myoclonus. Neurology. 1991 Aug; 41(8):1305-6. PMID: 1823535.
      Citations:    
    471. Kester DB, Saykin AJ, Sperling MR, O'Connor MJ, Robinson LJ, Gur RC. Acute effect of anterior temporal lobectomy on musical processing. Neuropsychologia. 1991; 29(7):703-8. PMID: 1944872.
      Citations:    
    472. Sperling MR. Neuroimaging in epilepsy: contribution of MRI, PET and SPECT. Semin Neurol. 1990 Dec; 10(4):349-56. PMID: 2287829.
      Citations:    
    473. Gzesh D, Goldstein S, Sperling MR, Alavi A. Complex partial epilepsy: the role of neuroimaging in localizing a seizure focus for surgical intervention. J Nucl Med. 1990 Nov; 31(11):1839-43. PMID: 2230998.
      Citations:    
    474. Stafiniak P, Saykin AJ, Sperling MR, Kester DB, Robinson LJ, O'Connor MJ, Gur RC. Acute naming deficits following dominant temporal lobectomy: prediction by age at 1st risk for seizures. Neurology. 1990 Oct; 40(10):1509-12. PMID: 2215940.
      Citations:    
    475. Sperling MR, O'Connor MJ. Auras and subclinical seizures: characteristics and prognostic significance. Ann Neurol. 1990 Sep; 28(3):320-8. PMID: 2241115.
      Citations:    
    476. Sperling MR, Gur RC, Alavi A, Gur RE, Resnick S, O'Connor MJ, Reivich M. Subcortical metabolic alterations in partial epilepsy. Epilepsia. 1990 Mar-Apr; 31(2):145-55. PMID: 2108014.
      Citations:    
    477. Sperling MR, O'Connor MJ. Comparison of depth and subdural electrodes in recording temporal lobe seizures. Neurology. 1989 Nov; 39(11):1497-504. PMID: 2812330.
      Citations:    
    478. Sperling MR, Cahan LD, Brown WJ. Relief of seizures from a predominantly posterior temporal tumor with anterior temporal lobectomy. Epilepsia. 1989 Sep-Oct; 30(5):559-63. PMID: 2792031.
      Citations:    
    479. Bridgman PA, Malamut BL, Sperling MR, Saykin AJ, O'Connor MJ. Memory during subclinical hippocampal seizures. Neurology. 1989 Jun; 39(6):853-6. PMID: 2725883.
      Citations:    
    480. Sperling MR, Lieb JP, Engel J, Crandall PH. Prognostic significance of independent auras in temporal lobe seizures. Epilepsia. 1989 May-Jun; 30(3):322-31. PMID: 2721465.
      Citations:    
    481. Sperling MR, Melmed S, McAllister T, Price TR. Lack of effect of naloxone on prolactin and seizures in electroconvulsive therapy. Epilepsia. 1989 Jan-Feb; 30(1):41-4. PMID: 2912716.
      Citations:    
    482. Brewer K, Sperling MR. Neurosurgical treatment of intractable epilepsy. J Neurosci Nurs. 1988 Dec; 20(6):366-72. PMID: 2975314.
      Citations:    
    483. Schroder T, Chen IW, Sperling M, Bell RH, Brackett K, Joffe SN. Hematoporphyrin derivative uptake and photodynamic therapy in pancreatic carcinoma. J Surg Oncol. 1988 May; 38(1):4-9. PMID: 2967404.
      Citations:    
    484. Sperling MR, Pritchard PB, Engel J, Daniel C, Sagel J. Prolactin in partial epilepsy: an indicator of limbic seizures. Ann Neurol. 1986 Dec; 20(6):716-22. PMID: 3101579.
      Citations:    
    485. Sperling MR, Wilson G, Engel J, Babb TL, Phelps M, Bradley W. Magnetic resonance imaging in intractable partial epilepsy: correlative studies. Ann Neurol. 1986 Jul; 20(1):57-62. PMID: 3488709.
      Citations:    
    486. Lieb JP, Sperling MR, Mendius JR, Skomer CE, Engel J. Visual versus computer evaluation of thiopental-induced EEG changes in temporal lobe epilepsy. Electroencephalogr Clin Neurophysiol. 1986 May; 63(5):395-407. PMID: 2420555.
      Citations:    
    487. Sperling MR, Wilson CL. The effect of limbic and extralimbic electrical stimulations upon prolactin secretion in humans. Brain Res. 1986 Apr 23; 371(2):293-7. PMID: 3697759.
      Citations:    
    488. Enrione EB, Gelfand MJ, Morgan D, Sperling M, Wagner SC, Popp MB. The effects of rate and route of nutrient intake on protein metabolism. J Surg Res. 1986 Apr; 40(4):320-5. PMID: 3084871.
      Citations:    
    489. Sperling MR. Childhood seizures after carbamazepine. N Engl J Med. 1986 Mar 27; 314(13):853. PMID: 3951524.
      Citations:    
    490. Sperling MR, Brown WJ, Crandall PH. Focal burst-suppression induced by thiopental. Electroencephalogr Clin Neurophysiol. 1986 Mar; 63(3):203-8. PMID: 2419076.
      Citations:    
    491. Sperling MR, Engel J. Sphenoidal electrodes. J Clin Neurophysiol. 1986 Jan; 3(1):67-73. PMID: 3949969.
      Citations:    
    492. Sperling MR, Mendius JR, Engel J. Mesial temporal spikes: a simultaneous comparison of sphenoidal, nasopharyngeal, and ear electrodes. Epilepsia. 1986 Jan-Feb; 27(1):81-6. PMID: 3948822.
      Citations:    
    493. Sperling MR, Herrmann C. Syndrome of palatal myoclonus and progressive ataxia: two cases with magnetic resonance imaging. Neurology. 1985 Aug; 35(8):1212-4. PMID: 4022358.
      Citations:    
    494. Sperling MR, Engel J. Electroencephalographic recording from the temporal lobes: a comparison of ear, anterior temporal, and nasopharyngeal electrodes. Ann Neurol. 1985 May; 17(5):510-3. PMID: 4004174.
      Citations:    
    495. Sperling MR. Hypoglycemic activation of focal abnormalities in the EEG of patients considered for temporal lobectomy. Electroencephalogr Clin Neurophysiol. 1984 Dec; 58(6):506-12. PMID: 6209099.
      Citations:    
    496. Kaplan LA, Cline D, Gartside P, Burstein S, Sperling M, Stein EA. Hemoglobin A1 in hemolysates from healthy and insulin-dependent diabetic children, as determined with a temperature-controlled minicolumn assay. Clin Chem. 1982 Jan; 28(1):13-8. PMID: 7034998.
      Citations:    
    497. Artal R, Platt LD, Sperling M, Kammula RK, Jilek J, Nakamura R. I. Maternal cardiovascular and metabolic responses in normal pregnancy. Am J Obstet Gynecol. 1981 May 15; 140(2):123-7. PMID: 7015863.
      Citations:    
    498. Chen IW, David R, Maxon HR, Sperling M, Stein EA. Age-, sex-, and race-related differences in myoglobin concentrations in the serum of healthy persons. Clin Chem. 1980 Dec; 26(13):1864-8. PMID: 7438432.
      Citations:    
    499. Nissley SP, Drash AL, Blizzard RM, Sperling M, Childs B. Comparison of juvenile diabetics with positive and negative organ specific antibody titers. Evidence for genetic heterogeneity. Diabetes. 1973 Jan; 22(1):63-5. PMID: 4683797.
      Citations:    
    500. Sperling M. Spider phobias and spider fantasies. A clinical contribution to the study of symbol and symptom choice. J Am Psychoanal Assoc. 1971 Jul; 19(3):472-98. PMID: 4110859.
      Citations:    
    501. SPERLING M. A FURTHER CONTRIBUTION TO THE PSYCHO-ANALYTIC STUDY OF MIGRAINE AND PSYCHOGENIC HEADACHES. THE RELATION OF MIGRAINE TO DEPRESSION, STATES OF WITHDRAWAL, PETIT MAL, AND EPILEPSY. Int J Psychoanal. 1964 Oct; 45:549-57. PMID: 14236193.
      Citations:    
    Sperling's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (880)
    Explore
    _
    Co-Authors (45)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _