Thomas Jefferson University

Margaret Kasner

TitleProfessor
InstitutionThomas Jefferson University
DepartmentMedical Oncology
Address834 Chestnut Street
Philadelphia PA 19107
Phone215-955-8874
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    Hematological malignancies & BMT

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kasner M, Fritsche AH, Leong MC, Cameron K, Lee CB, Lin TL, Lee JH, Brogan F, Kovak MR, Honeycutt H, Shaw K, George TJ. North American Cancer Center Clinical Research Capacity and Benchmarking in the Postpandemic Era. JCO Oncol Pract. 2024 Jul 01; OP2400164. PMID: 38950320.
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    2. Palmisiano N, Jeschke G, Wilde L, Alpdogan O, Carabasi M, Filicko-O'Hara J, Grosso D, Klumpp T, Martinez U, Wagner J, Carroll MP, Perl A, Kasner M. A Phase I Trial of Sirolimus with "7&3" Induction Chemotherapy in Patients with Newly Diagnosed Acute Myeloid Leukemia. Cancers (Basel). 2023 Oct 25; 15(21). PMID: 37958304.
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    3. Jamy OH, Kasner M, Wall S, Ingram S, Dent D', Dudley WN, Dudley L, Scott JM, Wujcik D. Integrating electronic geriatric assessment and frailty screening for adults with acute myeloid leukemia to drive personalized treatment decisions. Leuk Res. 2023 Sep 23; 134:107393. PMID: 37801913.
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    4. Wilde L, Porazzi P, Trotta R, De Dominici M, Palmisiano N, Keiffer G, Rancani K, Yingling K, Calabretta B, Kasner M. A phase I study of the combination of palbociclib and dexamethasone for the treatment of relapsed or refractory B-cell acute lymphoblastic leukemia. Leuk Res. 2023 Apr 06; 129:107075. PMID: 37079999.
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    5. Rosenberg M, Thapa S, Jeurkar C, Kasner M. Copper Deficiency Mimicking Myelodysplastic Syndrome: Zinc Supplementation in the Setting of COVID-19. Case Rep Oncol. 2023 Jan-Dec; 16(1):55-61. PMID: 36761368.
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    6. Benton C, Grunwald MR, Safah H, Kasner M. Co-management strategies for acute myeloid leukemia patients in the community setting. Front Oncol. 2022; 12:1060912. PMID: 36578924.
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    7. Kasner MT. Editorial:?Novel mechanisms for the treatment of AML before and after transplant. Front Oncol. 2022; 12:1063307. PMID: 36387087.
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    8. Edirisuriya C, Jeurkar C, Nazir B, Belovsky M, Kasner M. Immunophenotypic Differences in Cerebrospinal Fluid and Peripheral Blood Demonstrating Cancer Heterogenicity in Acute Myeloid Leukemia Patient. Case Rep Oncol. 2022 Sep-Dec; 15(3):874-880. PMID: 36825101.
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    9. Grosso D, Leiby B, Wilde L, Carabasi M, Filicko-O'Hara J, O'Hara W, Wagner JL, Mateja G, Alpdogan O, Binder A, Kasner M, Keiffer G, Klumpp T, Martinez UO, Palmisiano N, Porcu P, Gergis U, Flomenberg N. A Prospective, Randomized Trial Examining the Use of G-CSF Versus No G-CSF in Patients Post-Autologous Transplantation. Transplant Cell Ther. 2022 12; 28(12):831.e1-831.e7. PMID: 36167307.
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    10. Elliott ZT, Goldberg Z, Philips R, Johnson JM, Kasner MT, Kelly WK, Osipowicz S, Dampman R, Curry JM. Accrual-Monitoring Practices for Various Disease Trials among AACI Member Cancer Centers. Clin Pract. 2022 Aug 31; 12(5):692-700. PMID: 36136866.
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    11. Kasner MT, Halloran MB, Pan J, Ritchie EK, Fetterly GJ, Kramer D, Hangauer DG, Thompson JE. A phase Ib dose escalation study of oral monotherapy with KX2-391 in elderly patients with acute myeloid leukemia. Invest New Drugs. 2022 May 17. PMID: 35579731.
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    12. Wilde L, Kasner M. Whom should we treat with novel agents? Specific indications for specific and challenging populations. Hematology Am Soc Hematol Educ Program. 2021 12 10; 2021(1):24-29. PMID: 34889407.
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    13. Jeurkar C, Wilde L, Leiby BE, Banks J, Kasner M, Keiffer G, Filicko-O'Hara J, Palmisiano N. Inpatient versus outpatient hypomethylating agent induction for acute myeloid leukemia as a predictor for survival. Leuk Res. 2021 Apr; 103:106533. PMID: 33621825.
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    14. Yee K, Papayannidis C, Vey N, Dickinson MJ, Kelly KR, Assouline S, Kasner M, Seiter K, Drummond MW, Yoon SS, Lee JH, Blotner S, Jukofsky L, Pierceall WE, Zhi J, Simon S, Higgins B, Nichols G, Monnet A, Muehlbauer S, Ott M, Chen LC, Martinelli G. Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study?. Leuk Res. 2020 Dec 01; 100:106489. PMID: 33302031.
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    15. Wilde L, Isidori A, Keiffer G, Palmisiano N, Kasner M. Caring for AML Patients During the COVID-19 Crisis: An American and Italian Experience. Front Oncol. 2020; 10:1689. PMID: 32984046.
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    16. Wilde L, Ramanathan S, Kasner M. B-cell lymphoma-2 inhibition and resistance in acute myeloid leukemia. World J Clin Oncol. 2020 Aug 24; 11(8):528-540. PMID: 32879842.
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    17. Grosso D, Carabasi M, Filicko-O'Hara J, Wagner JL, O'Hara W, Sun M, Colombe B, Shi W, Werner-Wasik M, Rudolph S, Alpdogan O, Binder A, Kasner M, Klumpp T, Martinez-Outschoorn U, Palmisiano N, Wilde L, Porcu P, Gergis U, Flomenberg N. Low Nonrelapse Mortality after HLA-Matched Related 2-Step Hematopoietic Stem Cell Transplantation Using Cyclophosphamide for Graft-versus-Host Disease Prophylaxis and the Potential Impact of Non- Cyclophosphamide-Exposed T Cells on Outcomes. Biol Blood Marrow Transplant. 2020 Jul 03. PMID: 32629157.
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    18. Kasner MT. Outpatient administration of liposomal daunorubicin and cytarabine (Vyxeos) in patients with secondary acute myeloid leukemia. Clin Adv Hematol Oncol. 2019 Nov; 17(11):604-606. PMID: 31851160.
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    19. Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Paolini S, Montesinos P, Baer MR, Larson RA, Ustun C, Fabbiano F, Erba HP, Di Stasi A, Stuart R, Olin R, Kasner M, Ciceri F, Chou WC, Podoltsev N, Recher C, Yokoyama H, Hosono N, Yoon SS, Lee JH, Pardee T, Fathi AT, Liu C, Hasabou N, Liu X, Bahceci E, Levis MJ. Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML. N Engl J Med. 2019 10 31; 381(18):1728-1740. PMID: 31665578.
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    20. Ross NA, Osley KL, Sahu J, Kasner M, Hess B. Mycobacterium haemophilum: a challenging treatment dilemma in an immunocompromised patient. Cutis. 2019 Sep; 104(3):E7-E10. PMID: 31675403.
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    21. Chen J, Pan J, Zhan T, Tuazon S, Saini N, O'Hara W, Filicko-O'Hara J, Klumpp T, Kasner M, Carabasi M, Porcu P, Wagner JL. Autologous Stem Cell Transplantation for Multiple Myeloma: Growth Factor Matters. Biol Blood Marrow Transplant. 2019 Jun 04. PMID: 31173899.
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    22. McBride A, Houtmann S, Wilde L, Vigil C, Eischen CM, Kasner M, Palmisiano N. The Role of Inhibition of Apoptosis in Acute Leukemias and Myelodysplastic Syndrome. Front Oncol. 2019; 9:192. PMID: 30972300.
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    23. Kasner MT, Mick R, Jeschke GR, Carabasi M, Filicko-O'Hara J, Flomenberg N, Frey NV, Hexner EO, Luger SM, Loren AW, Mangan JK, Wagner JL, Weiss M, Carroll M, Perl AE. Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition. Invest New Drugs. 2018 Apr 02. PMID: 29607465.
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    24. Hannon M, Wilde L, Nwaoduah N, Kasner M. Chronic myelomonocytic leukemia with central nervous system involvement. Leuk Lymphoma. 2018 Jan 11; 1-2. PMID: 29322838.
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    25. Chen J, Pan J, Filicko-O'Hara J, Kasner M, Flomenberg P. Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient. IDCases. 2017; 9:73-76. PMID: 28706856.
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    26. Reis B, Jukofsky L, Chen G, Martinelli G, Zhong H, So WV, Dickinson MJ, Drummond M, Assouline S, Hashemyan M, Theron M, Blotner S, Lee JH, Kasner M, Yoon SS, Rueger R, Seiter K, Middleton SA, Kelly KR, Vey N, Yee K, Nichols G, Chen LC, Pierceall WE. Acute myeloid leukemia patients' clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts. Haematologica. 2016 May; 101(5):e185-8. PMID: 26869629.
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    27. Palmisiano ND, Kasner MT. Polo-like kinase and its inhibitors: Ready for the match to start? Am J Hematol. 2015 Nov; 90(11):1071-6. PMID: 26294255.
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    28. Gaballa S, Palmisiano N, Alpdogan O, Carabasi M, Filicko-O'Hara J, Kasner M, Kraft WK, Leiby B, Martinez-Outschoorn U, O'Hara W, Pro B, Rudolph S, Sharma M, Wagner JL, Weiss M, Flomenberg N, Grosso D. A Two-Step Haploidentical Versus a Two-Step Matched Related Allogeneic Myeloablative Peripheral Blood Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 Jan; 22(1):141-8. PMID: 26415558.
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    29. Grosso D, Gaballa S, Alpdogan O, Carabasi M, Filicko-O'Hara J, Kasner M, Martinez-Outschoorn U, Wagner JL, O'Hara W, Rudolph S, Chervoneva I, Colombe B, Farley PC, Flomenberg P, Pro B, Sharma M, Shi W, Weiss M, Flomenberg N. A two-step approach to myeloablative haploidentical transplantation: low nonrelapse mortality and high survival confirmed in patients with earlier stage disease. Biol Blood Marrow Transplant. 2015 Apr; 21(4):646-52. PMID: 25542159.
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    30. Bruminhent J, Wang ZX, Hu C, Wagner J, Sunday R, Bobik B, Hegarty S, Keith S, Alpdogan S, Carabasi M, Filicko-O'Hara J, Flomenberg N, Kasner M, Outschoorn UM, Weiss M, Flomenberg P. Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2014 Sep; 20(9):1329-34. PMID: 24792871.
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    31. Kasner MT, Weiss M. Treatment of adult ALL: more questions than answers. Oncology (Williston Park). 2012 Sep; 26(9):865, 869-70. PMID: 23061345.
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    32. Perl AE, Kasner MT, Shank D, Luger SM, Carroll M. Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy. Clin Cancer Res. 2012 Mar 15; 18(6):1716-25. PMID: 22167413.
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    33. Grosso D, Carabasi M, Filicko-O'Hara J, Kasner M, Wagner JL, Colombe B, Cornett Farley P, O'Hara W, Flomenberg P, Werner-Wasik M, Brunner J, Mookerjee B, Hyslop T, Weiss M, Flomenberg N. A 2-step approach to myeloablative haploidentical stem cell transplantation: a phase 1/2 trial performed with optimized T-cell dosing. Blood. 2011 Oct 27; 118(17):4732-9. PMID: 21868572.
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    34. Kasner MT. Novel targets for treatment of adult acute lymphocytic leukemia. Curr Hematol Malig Rep. 2010 Oct; 5(4):207-12. PMID: 20680526.
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    35. Perl AE, Kasner MT, Tsai DE, Vogl DT, Loren AW, Schuster SJ, Porter DL, Stadtmauer EA, Goldstein SC, Frey NV, Nasta SD, Hexner EO, Dierov JK, Swider CR, Bagg A, Gewirtz AM, Carroll M, Luger SM. A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia. Clin Cancer Res. 2009 Nov 1; 15(21):6732-9. PMID: 19843663.
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    36. Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA. The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest. 2009 Jul; 119(7):1888-98. PMID: 19487809.
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    37. Kasner MT, Luger SM. Update on the therapy for myelodysplastic syndrome. Am J Hematol. 2009 Mar; 84(3):177-86. PMID: 19195035.
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    38. Frey NV, Leid CE, Nowell PC, Tomczak E, Strauser HT, Kasner M, Goldstein S, Loren A, Stadtmauer E, Luger S, Hexner E, Hinkle J, Porter DL. Trisomy 8 in an allogeneic stem cell transplant recipient representative of a donor-derived constitutional abnormality. Am J Hematol. 2008 Nov; 83(11):846-9. PMID: 18819096.
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    39. Kasner MT, Laury A, Kasner SE, Carroll M, Luger SM. Increased cerebral blood flow after leukapheresis for acute myelogenous leukemia. Am J Hematol. 2007 Dec; 82(12):1110-2. PMID: 17654677.
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    40. Ky B, Kasner M, Carver JR. von Willebrand disease and coronary artery disease: a contemporary review. J Invasive Cardiol. 2006 Apr; 18(4):178-82. PMID: 16729396.
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