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Margaret Kasner

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentMedical Oncology
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    Collapse Overview 
    Collapse overview
    Hematological malignancies & BMT


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yee K, Papayannidis C, Vey N, Dickinson MJ, Kelly KR, Assouline S, Kasner M, Seiter K, Drummond MW, Yoon SS, Lee JH, Blotner S, Jukofsky L, Pierceall WE, Zhi J, Simon S, Higgins B, Nichols G, Monnet A, Muehlbauer S, Ott M, Chen LC, Martinelli G. Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study?. Leuk Res. 2020 Dec 01; 100:106489. PMID: 33302031.
      View in: PubMed
    2. Wilde L, Isidori A, Keiffer G, Palmisiano N, Kasner M. Caring for AML Patients During the COVID-19 Crisis: An American and Italian Experience. Front Oncol. 2020; 10:1689. PMID: 32984046.
      View in: PubMed
    3. Wilde L, Ramanathan S, Kasner M. B-cell lymphoma-2 inhibition and resistance in acute myeloid leukemia. World J Clin Oncol. 2020 Aug 24; 11(8):528-540. PMID: 32879842.
      View in: PubMed
    4. Grosso D, Carabasi M, Filicko-O'Hara J, Wagner JL, O'Hara W, Sun M, Colombe B, Shi W, Werner-Wasik M, Rudolph S, Alpdogan O, Binder A, Kasner M, Klumpp T, Martinez-Outschoorn U, Palmisiano N, Wilde L, Porcu P, Gergis U, Flomenberg N. Low Nonrelapse Mortality after HLA-Matched Related 2-Step Hematopoietic Stem Cell Transplantation Using Cyclophosphamide for Graft-versus-Host Disease Prophylaxis and the Potential Impact of Non- Cyclophosphamide-Exposed T Cells on Outcomes. Biol Blood Marrow Transplant. 2020 Jul 03. PMID: 32629157.
      View in: PubMed
    5. Kasner MT. Outpatient administration of liposomal daunorubicin and cytarabine (Vyxeos) in patients with secondary acute myeloid leukemia. Clin Adv Hematol Oncol. 2019 Nov; 17(11):604-606. PMID: 31851160.
      View in: PubMed
    6. Perl AE, Martinelli G, Cortes JE, Neubauer A, Berman E, Paolini S, Montesinos P, Baer MR, Larson RA, Ustun C, Fabbiano F, Erba HP, Di Stasi A, Stuart R, Olin R, Kasner M, Ciceri F, Chou WC, Podoltsev N, Recher C, Yokoyama H, Hosono N, Yoon SS, Lee JH, Pardee T, Fathi AT, Liu C, Hasabou N, Liu X, Bahceci E, Levis MJ. Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML. N Engl J Med. 2019 10 31; 381(18):1728-1740. PMID: 31665578.
      View in: PubMed
    7. Ross NA, Osley KL, Sahu J, Kasner M, Hess B. Mycobacterium haemophilum: a challenging treatment dilemma in an immunocompromised patient. Cutis. 2019 Sep; 104(3):E7-E10. PMID: 31675403.
      View in: PubMed
    8. Chen J, Pan J, Zhan T, Tuazon S, Saini N, O'Hara W, Filicko-O'Hara J, Klumpp T, Kasner M, Carabasi M, Porcu P, Wagner JL. Autologous Stem Cell Transplantation for Multiple Myeloma: Growth Factor Matters. Biol Blood Marrow Transplant. 2019 Jun 04. PMID: 31173899.
      View in: PubMed
    9. McBride A, Houtmann S, Wilde L, Vigil C, Eischen CM, Kasner M, Palmisiano N. The Role of Inhibition of Apoptosis in Acute Leukemias and Myelodysplastic Syndrome. Front Oncol. 2019; 9:192. PMID: 30972300.
      View in: PubMed
    10. Kasner MT, Mick R, Jeschke GR, Carabasi M, Filicko-O'Hara J, Flomenberg N, Frey NV, Hexner EO, Luger SM, Loren AW, Mangan JK, Wagner JL, Weiss M, Carroll M, Perl AE. Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition. Invest New Drugs. 2018 Apr 02. PMID: 29607465.
      View in: PubMed
    11. Hannon M, Wilde L, Nwaoduah N, Kasner M. Chronic myelomonocytic leukemia with central nervous system involvement. Leuk Lymphoma. 2018 Jan 11; 1-2. PMID: 29322838.
      View in: PubMed
    12. Chen J, Pan J, Filicko-O'Hara J, Kasner M, Flomenberg P. Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient. IDCases. 2017; 9:73-76. PMID: 28706856.
      View in: PubMed
    13. Reis B, Jukofsky L, Chen G, Martinelli G, Zhong H, So WV, Dickinson MJ, Drummond M, Assouline S, Hashemyan M, Theron M, Blotner S, Lee JH, Kasner M, Yoon SS, Rueger R, Seiter K, Middleton SA, Kelly KR, Vey N, Yee K, Nichols G, Chen LC, Pierceall WE. Acute myeloid leukemia patients' clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts. Haematologica. 2016 May; 101(5):e185-8. PMID: 26869629.
      View in: PubMed
    14. Palmisiano ND, Kasner MT. Polo-like kinase and its inhibitors: Ready for the match to start? Am J Hematol. 2015 Nov; 90(11):1071-6. PMID: 26294255.
      View in: PubMed
    15. Gaballa S, Palmisiano N, Alpdogan O, Carabasi M, Filicko-O'Hara J, Kasner M, Kraft WK, Leiby B, Martinez-Outschoorn U, O'Hara W, Pro B, Rudolph S, Sharma M, Wagner JL, Weiss M, Flomenberg N, Grosso D. A Two-Step Haploidentical Versus a Two-Step Matched Related Allogeneic Myeloablative Peripheral Blood Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 Jan; 22(1):141-8. PMID: 26415558.
      View in: PubMed
    16. Grosso D, Gaballa S, Alpdogan O, Carabasi M, Filicko-O'Hara J, Kasner M, Martinez-Outschoorn U, Wagner JL, O'Hara W, Rudolph S, Chervoneva I, Colombe B, Farley PC, Flomenberg P, Pro B, Sharma M, Shi W, Weiss M, Flomenberg N. A two-step approach to myeloablative haploidentical transplantation: low nonrelapse mortality and high survival confirmed in patients with earlier stage disease. Biol Blood Marrow Transplant. 2015 Apr; 21(4):646-52. PMID: 25542159.
      View in: PubMed
    17. Bruminhent J, Wang ZX, Hu C, Wagner J, Sunday R, Bobik B, Hegarty S, Keith S, Alpdogan S, Carabasi M, Filicko-O'Hara J, Flomenberg N, Kasner M, Outschoorn UM, Weiss M, Flomenberg P. Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2014 Sep; 20(9):1329-34. PMID: 24792871.
      View in: PubMed
    18. Kasner MT, Weiss M. Treatment of adult ALL: more questions than answers. Oncology (Williston Park). 2012 Sep; 26(9):865, 869-70. PMID: 23061345.
      View in: PubMed
    19. Perl AE, Kasner MT, Shank D, Luger SM, Carroll M. Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy. Clin Cancer Res. 2012 Mar 15; 18(6):1716-25. PMID: 22167413.
      View in: PubMed
    20. Grosso D, Carabasi M, Filicko-O'Hara J, Kasner M, Wagner JL, Colombe B, Cornett Farley P, O'Hara W, Flomenberg P, Werner-Wasik M, Brunner J, Mookerjee B, Hyslop T, Weiss M, Flomenberg N. A 2-step approach to myeloablative haploidentical stem cell transplantation: a phase 1/2 trial performed with optimized T-cell dosing. Blood. 2011 Oct 27; 118(17):4732-9. PMID: 21868572.
      View in: PubMed
    21. Kasner MT. Novel targets for treatment of adult acute lymphocytic leukemia. Curr Hematol Malig Rep. 2010 Oct; 5(4):207-12. PMID: 20680526.
      View in: PubMed
    22. Perl AE, Kasner MT, Tsai DE, Vogl DT, Loren AW, Schuster SJ, Porter DL, Stadtmauer EA, Goldstein SC, Frey NV, Nasta SD, Hexner EO, Dierov JK, Swider CR, Bagg A, Gewirtz AM, Carroll M, Luger SM. A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia. Clin Cancer Res. 2009 Nov 1; 15(21):6732-9. PMID: 19843663.
      View in: PubMed
    23. Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA. The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest. 2009 Jul; 119(7):1888-98. PMID: 19487809.
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    24. Kasner MT, Luger SM. Update on the therapy for myelodysplastic syndrome. Am J Hematol. 2009 Mar; 84(3):177-86. PMID: 19195035.
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    25. Frey NV, Leid CE, Nowell PC, Tomczak E, Strauser HT, Kasner M, Goldstein S, Loren A, Stadtmauer E, Luger S, Hexner E, Hinkle J, Porter DL. Trisomy 8 in an allogeneic stem cell transplant recipient representative of a donor-derived constitutional abnormality. Am J Hematol. 2008 Nov; 83(11):846-9. PMID: 18819096.
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    26. Kasner MT, Laury A, Kasner SE, Carroll M, Luger SM. Increased cerebral blood flow after leukapheresis for acute myelogenous leukemia. Am J Hematol. 2007 Dec; 82(12):1110-2. PMID: 17654677.
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    27. Ky B, Kasner M, Carver JR. von Willebrand disease and coronary artery disease: a contemporary review. J Invasive Cardiol. 2006 Apr; 18(4):178-82. PMID: 16729396.
      View in: PubMed
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