Miki Fujioka

TitleInstructor
InstitutionThomas Jefferson University
DepartmentBiochemistry & Molecular Biology - Thomas Jefferson University
Address1020 Locust Street
Philadelphia PA 19107
Phone2155034774
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Fujioka M, Ke W, Schedl P, Jaynes JB. The homie insulator has sub-elements with different insulating and long-range pairing properties. Genetics. 2025 Feb 25. PMID: 39999387.
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    2. Fujioka M, Ke W, Schedl P, Jaynes JB. The homie insulator has sub-elements with different insulating and long-range pairing properties. bioRxiv. 2025 Jan 26. PMID: 39896478.
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    3. Fujioka M, Nezdyur A, Jaynes JB. An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference. PLoS Genet. 2021 Apr; 17(4):e1009536. PMID: 33901190.
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    4. Yamamoto H, Ueshima K, Saito M, Ikoma K, Ishida M, Goto T, Hayashi S, Ikegami A, Fujioka M, Mazda O, Kubo T. Evaluation of femoral perfusion using dynamic contrast-enhanced MRI after simultaneous initiation of electrical stimulation and steroid treatment in an osteonecrosis model. Electromagn Biol Med. 2018; 37(2):84-94. PMID: 29708772.
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    5. Fujioka M, Mistry H, Schedl P, Jaynes JB. Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. PLoS Genet. 2016 Feb; 12(2):e1005889. PMID: 26910731.
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    6. Saito M, Ueshima K, Fujioka M, Ishida M, Goto T, Arai Y, Ikoma K, Fujiwara H, Fukushima W, Kubo T. Corticosteroid administration within 2 weeks after renal transplantation affects the incidence of femoral head osteonecrosis. Acta Orthop. 2014 Jun; 85(3):266-70. PMID: 24786907.
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    7. Fujioka M, Sun G, Jaynes JB. The Drosophila eve Insulator Homie Promotes eve Expression and Protects the Adjacent Gene from Repression by Polycomb Spreading. PLoS Genet. 2013 Oct; 9(10):e1003883. PMID: 24204298.
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    8. Fujioka M, Gebelein B, Cofer ZC, Mann RS, Jaynes JB. Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired. Dev Biol. 2012 Jun 15; 366(2):382-92. PMID: 22537495.
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    9. Fujioka M, Jaynes JB. Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers. Dev Biol. 2012 Feb 15; 362(2):309-19. PMID: 22178246.
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    10. Johnston DM, Sedkov Y, Petruk S, Riley KM, Fujioka M, Jaynes JB, Mazo A. Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development. Mol Cell. 2011 Oct 7; 44(1):51-61. PMID: 21981918.
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    11. Goto T, Fujioka M, Ishida M, Kuribayashi M, Ueshima K, Kubo T. Noninvasive up-regulation of angiopoietin-2 and fibroblast growth factor-2 in bone marrow by pulsed electromagnetic field therapy. J Orthop Sci. 2010 Sep; 15(5):661-5. PMID: 20953928.
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    12. Kuribayashi M, Fujioka M, Takahashi KA, Arai Y, Ishida M, Goto T, Kubo T. Vitamin E prevents steroid-induced osteonecrosis in rabbits. Acta Orthop. 2010 Feb; 81(1):154-60. PMID: 20146637.
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    13. Fujioka M, Wu X, Jaynes JB. A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication. Development. 2009 Sep; 136(18):3077-87. PMID: 19675129.
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    14. Kido K, Fujioka M, Takahashi K, Ueshima K, Goto T, Kubo T. Short-term results of the S-ROM-A femoral prosthesis operative strategies for Asian patients with osteoarthritis. J Arthroplasty. 2009 Dec; 24(8):1193-9. PMID: 19369026.
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    15. Fujioka M, Yusibova GL, Zhou J, Jaynes JB. The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site. Development. 2008 Dec; 135(24):4131-9. PMID: 19029043.
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    16. Khan FS, Fujioka M, Datta P, Fernandes-Alnemri T, Jaynes JB, Alnemri ES. The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila. Cell Death Differ. 2008 Jun; 15(6):1073-83. PMID: 18259196.
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    17. Fujioka M, Wessells RJ, Han Z, Liu J, Fitzgerald K, Yusibova GL, Zamora M, Ruiz-Lozano P, Bodmer R, Jaynes JB. Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan. Circ Res. 2005 Nov 25; 97(11):1108-14. PMID: 16239588.
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    18. Jaynes JB, Fujioka M. Drawing lines in the sand: even skipped et al. and parasegment boundaries. Dev Biol. 2004 May 15; 269(2):609-22. PMID: 15110723.
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    19. Fujioka M, Lear BC, Landgraf M, Yusibova GL, Zhou J, Riley KM, Patel NH, Jaynes JB. Even-skipped, acting as a repressor, regulates axonal projections in Drosophila. Development. 2003 Nov; 130(22):5385-400. PMID: 13129849.
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    20. Kobayashi M, Fujioka M, Tolkunova EN, Deka D, Abu-Shaar M, Mann RS, Jaynes JB. Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila. Development. 2003 Feb; 130(4):741-51. PMID: 12506004.
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    21. Fujioka M, Yusibova GL, Patel NH, Brown SJ, Jaynes JB. The repressor activity of Even-skipped is highly conserved, and is sufficient to activate engrailed and to regulate both the spacing and stability of parasegment boundaries. Development. 2002 Oct; 129(19):4411-21. PMID: 12223400.
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    22. Srinivasula SM, Datta P, Kobayashi M, Wu JW, Fujioka M, Hegde R, Zhang Z, Mukattash R, Fernandes-Alnemri T, Shi Y, Jaynes JB, Alnemri ES. sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Curr Biol. 2002 Jan 22; 12(2):125-30. PMID: 11818063.
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    23. Kobayashi M, Goldstein RE, Fujioka M, Paroush Z, Jaynes JB. Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries. Development. 2001 May; 128(10):1805-15. PMID: 11311161.
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    24. Fujioka M, Jaynes JB, Bejsovec A, Weir M. Production of transgenic Drosophila. Methods Mol Biol. 2000; 136:353-63. PMID: 10840724.
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    25. Sackerson C, Fujioka M, Goto T. The even-skipped locus is contained in a 16-kb chromatin domain. Dev Biol. 1999 Jul 01; 211(1):39-52. PMID: 10373303.
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    26. Tillib S, Petruk S, Sedkov Y, Kuzin A, Fujioka M, Goto T, Mazo A. Trithorax- and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences. Mol Cell Biol. 1999 Jul; 19(7):5189-202. PMID: 10373568.
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    27. Fujioka M, Emi-Sarker Y, Yusibova GL, Goto T, Jaynes JB. Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients. Development. 1999 Jun; 126(11):2527-38. PMID: 10226011.
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    28. Tolkunova EN, Fujioka M, Kobayashi M, Deka D, Jaynes JB. Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genes. Mol Cell Biol. 1998 May; 18(5):2804-14. PMID: 9566899.
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    29. Fujioka M, Miskiewicz P, Raj L, Gulledge AA, Weir M, Goto T. Drosophila Paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain. Development. 1996 Sep; 122(9):2697-707. PMID: 8787744.
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    30. Fujioka M, Yusibova GL, Sackerson CM, Tillib S, Mazo A, Satake M, Goto T. Runt domain partner proteins enhance DNA binding and transcriptional repression in cultured Drosophila cells. Genes Cells. 1996 Aug; 1(8):741-54. PMID: 9077443.
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    31. Fujioka M, Jaynes JB, Goto T. Early even-skipped stripes act as morphogenetic gradients at the single cell level to establish engrailed expression. Development. 1995 Dec; 121(12):4371-82. PMID: 8575337.
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