Thomas Jefferson University

Ronald Freudenberger

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address1025 Walnut St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mehta NA, Saqi B, Sabzwari SRA, Gupta R, Vyas A, Gordon J, Cossu S, Nazir T, Freudenberger R, Bozorgnia B. Durability of left bundle branch area pacing. J Cardiovasc Electrophysiol. 2022 07; 33(7):1529-1536. PMID: 35586896.
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    2. Lee TC, Qian M, Liu Y, Graham S, Mann DL, Nakanishi K, Teerlink JR, Lip GYH, Freudenberger RS, Sacco RL, Mohr JP, Labovitz AJ, Ponikowski P, Lok DJ, Matsumoto K, Estol C, Anker SD, Pullicino PM, Buchsbaum R, Levin B, Thompson JLP, Homma S, Di Tullio MR. Cognitive Decline Over Time in Patients With Systolic Heart?Failure: Insights From WARCEF. JACC Heart Fail. 2019 12; 7(12):1042-1053. PMID: 31779926.
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    3. Bettin M, Louis-Jacques A, Romagano MP, Cabrera I, Ahnert A, Freudenberger R, Qui?ones JN. Novel collaborative cardiology and maternal fetal medicine practice - experience at the heart and pregnancy program. J Matern Fetal Neonatal Med. 2021 May; 34(10):1570-1575. PMID: 31269843.
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    4. Shah N, Qian M, Di Tullio MR, Graham S, Mann DL, Sacco RL, Lip GYH, Labovitz AJ, Ponikowski P, Lok DJ, Anker SD, Teerlink JR, Thompson JLP, Homma S, Freudenberger RS. Pulse pressure and prognosis in patients with heart failure with reduced ejection fraction. Eur J Clin Invest. 2019 Jun; 49(6):e13092. PMID: 30801690.
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    5. Lee TC, Qian M, Mu L, Di Tullio MR, Graham S, Mann DL, Nakanishi K, Teerlink JR, Lip GYH, Freudenberger RS, Sacco RL, Mohr JP, Labovitz AJ, Ponikowski P, Lok DJ, Estol C, Anker SD, Pullicino PM, Buchsbaum R, Levin B, Thompson JLP, Homma S, Ye S. Association between mortality and implantable cardioverter-defibrillators by aetiology of heart failure: a propensity-matched analysis of the WARCEF trial. ESC Heart Fail. 2019 Apr; 6(2):297-307. PMID: 30816013.
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    6. Romagano M, Louis-Jacques A, Quinones J, Freudenberger R, Fleming L, Smulian J, Martinez M. Is there a role for cardiac magnetic resonance imaging during pregnancy? J Matern Fetal Neonatal Med. 2020 Feb; 33(4):558-563. PMID: 29973095.
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    7. Patel B, Secheresiu P, Shah M, Racharla L, Alsalem AB, Agarwal M, Tripathi B, Sablani N, Garg L, Patil S, Islam N, Ray D, Ogunniyi MO, Freudenberger R. Trends and Predictors of Palliative Care Referrals in Patients With Acute Heart Failure. Am J Hosp Palliat Care. 2019 Feb; 36(2):147-153. PMID: 30157670.
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    8. Di Tullio MR, Qian M, Thompson JLP, Labovitz AJ, Mann DL, Sacco RL, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Lip GYH, Levin B, Mohr JP, Buchsbaum R, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Homma S. Left atrial volume and cardiovascular outcomes in systolic heart failure: effect of antithrombotic treatment. ESC Heart Fail. 2018 10; 5(5):800-808. PMID: 30015405.
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    9. Lee TC, Qian M, Lip GYH, Di Tullio MR, Graham S, Mann DL, Nakanishi K, Teerlink JR, Freudenberger RS, Sacco RL, Mohr JP, Labovitz AJ, Ponikowski P, Lok DJ, Estol C, Anker SD, Pullicino PM, Buchsbaum R, Levin B, Thompson JLP, Homma S, Ye S. Heart Failure Severity and Quality of Warfarin Anticoagulation Control (From the WARCEF Trial). Am J Cardiol. 2018 09 01; 122(5):821-827. PMID: 30037426.
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    10. Freudenberger RS. Risk Scores-Medical Derivatives. J Am Coll Cardiol. 2018 02 20; 71(7):736-738. PMID: 29447734.
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    11. Teerlink JR, Qian M, Bello NA, Freudenberger RS, Levin B, Di Tullio MR, Graham S, Mann DL, Sacco RL, Mohr JP, Lip GYH, Labovitz AJ, Lee SC, Ponikowski P, Lok DJ, Anker SD, Thompson JLP, Homma S. Aspirin Does Not Increase Heart Failure?Events in Heart Failure Patients: From the WARCEF?Trial. JACC Heart Fail. 2017 08; 5(8):603-610. PMID: 28774396.
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    12. Garg J, Shah N, Krishnamoorthy P, Mehta K, Bozorgnia B, Boyle NG, Freudenberger R, Natale A. Catheter ablation of accessory pathway: 14-year trends in utilization and complications in adults in the United States. Int J Cardiol. 2017 Dec 01; 248:196-200. PMID: 28712558.
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    13. Nakanishi K, Di Tullio MR, Qian M, Thompson JLP, Labovitz AJ, Mann DL, Sacco RL, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Lip GYH, Levin B, Mohr JP, Buchsbaum R, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Homma S. Resting Heart Rate and Ischemic Stroke in Patients with Heart Failure. Cerebrovasc Dis. 2017; 44(1-2):43-50. PMID: 28419982.
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    14. Chaudhary R, Garg J, Krishnamoorthy P, Shah N, Feldman BA, Martinez MW, Freudenberger R. On-X Valve: The Next Generation Aortic Valve. Cardiol Rev. 2017 Mar/Apr; 25(2):77-83. PMID: 28170357.
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    15. Shah N, Chaudhary R, Mehta K, Agarwal V, Garg J, Freudenberger R, Jacobs L, Cox D, Kern KB, Patel N. Reply: Do We Need Individualized Therapeutic Strategies in High-Risk Patients Treated With Hypothermia? JACC Cardiovasc Interv. 2017 01 09; 10(1):105-106. PMID: 28057280.
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    16. Shah N, Chaudhary R, Mehta K, Agarwal V, Garg J, Freudenberger R, Jacobs L, Cox D, Kern KB, Patel N. Therapeutic Hypothermia and Stent?Thrombosis: A Nationwide Analysis. JACC Cardiovasc Interv. 2016 09 12; 9(17):1801-11. PMID: 27609254.
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    17. Ye S, Qian M, Zhao B, Buchsbaum R, Sacco RL, Levin B, Di Tullio MR, Mann DL, Pullicino PM, Freudenberger RS, Teerlink JR, Mohr JP, Graham S, Labovitz AJ, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Lip GY, Thompson JL, Homma S. CHA2 DS2 -VASc score and adverse outcomes in patients with heart failure with reduced ejection fraction and sinus rhythm. Eur J Heart Fail. 2016 Oct; 18(10):1261-1266. PMID: 27444219.
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    18. Di Tullio MR, Qian M, Thompson JL, Labovitz AJ, Mann DL, Sacco RL, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Lip GY, Levin B, Mohr JP, Buchsbaum R, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Homma S. Left Ventricular Ejection Fraction and Risk of Stroke and Cardiac Events in Heart Failure: Data From the Warfarin Versus Aspirin in Reduced Ejection Fraction Trial. Stroke. 2016 08; 47(8):2031-7. PMID: 27354224.
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    19. Shah M, Garg J, Patel B, Guthier J, Freudenberger RS. Can your heart handle the spice: A case of acute myocardial infarction and left ventricular apical thrombus. Int J Cardiol. 2016 Jul 15; 215:129-31. PMID: 27111175.
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    20. Kato TS, Di Tullio MR, Qian M, Wu M, Thompson JL, Mann DL, Sacco RL, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Lip GY, Levin B, Mohr JP, Labovitz AJ, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Homma S. Clinical and Echocardiographic Factors Associated With New-Onset Atrial Fibrillation in Heart Failure - Subanalysis of the WARCEF Trial. Circ J. 2016; 80(3):619-26. PMID: 26804607.
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    21. Bennett CE, Freudenberger R. The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature. Cardiol Res Pract. 2016; 2016:5172308. PMID: 26881173.
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    22. Chaudhary R, Garg J, Krishnamoorthy P, Shah N, Lanier G, Martinez MW, Freudenberger R. Ivabradine: Heart Failure and Beyond. J Cardiovasc Pharmacol Ther. 2016 07; 21(4):335-43. PMID: 26721645.
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    23. Shah N, Agarwal V, Patel N, Deshmukh A, Chothani A, Garg J, Badheka A, Martinez M, Islam N, Freudenberger R. National Trends in Utilization, Mortality, Complications, and Cost of Care After Left Ventricular Assist Device Implantation From 2005 to 2011. Ann Thorac Surg. 2016 Apr; 101(4):1477-84. PMID: 26588867.
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    24. Freudenberger RS, Cheng B, Mann DL, Thompson JL, Sacco RL, Buchsbaum R, Sanford A, Pullicino PM, Levin B, Teerlink JR, Graham S, Mohr JP, Labovitz AJ, Di Tullio MR, Lip GY, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Homma S. The first prognostic model for stroke and death in patients with systolic heart failure. J Cardiol. 2016 08; 68(2):100-3. PMID: 26549533.
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    25. Shah N, Chothani A, Agarwal V, Deshmukh A, Patel N, Garg J, Badheka A, Martinez M, Islam N, Freudenberger R. Impact of Annual Hospital Volume on Outcomes after Left Ventricular Assist Device (LVAD) Implantation in the Contemporary Era. J Card Fail. 2016 Mar; 22(3):232-7. PMID: 26547012.
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    26. Ye S, Cheng B, Lip GY, Buchsbaum R, Sacco RL, Levin B, Di Tullio MR, Qian M, Mann DL, Pullicino PM, Freudenberger RS, Teerlink JR, Mohr JP, Graham S, Labovitz AJ, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Thompson JL, Homma S. Bleeding Risk and Antithrombotic Strategy in Patients With Sinus Rhythm and Heart Failure With Reduced Ejection Fraction Treated With Warfarin or Aspirin. Am J Cardiol. 2015 Sep 15; 116(6):904-12. PMID: 26189039.
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    27. Homma S, Thompson JL, Qian M, Ye S, Di Tullio MR, Lip GY, Mann DL, Sacco RL, Levin B, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Mohr JP, Labovitz AJ, Buchsbaum R, Estol CJ, Lok DJ, Ponikowski P, Anker SD. Quality of anticoagulation control in preventing adverse events in patients with heart failure in sinus rhythm: Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction trial substudy. Circ Heart Fail. 2015 May; 8(3):504-9. PMID: 25850425.
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    28. Muppidi R, Spranklin L, Scialla W, Islam N, Freudenberger R, Malacoff R. Cardiotoxicity of Anticancer Therapies. Rev Cardiovasc Med. 2015; 16(4):225-34. PMID: 26827744.
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    29. Shaffer JA, Thompson JL, Cheng B, Ye S, Lip GY, Mann DL, Sacco RL, Pullicino PM, Freudenberger RS, Graham S, Mohr JP, Labovitz AJ, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Di Tullio MR, Homma S. Association of quality of life with anticoagulant control in patients with heart failure: the Warfarin and Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) trial. Int J Cardiol. 2014 Dec 15; 177(2):715-7. PMID: 25456692.
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    30. Graham S, Ye S, Qian M, Sanford AR, Di Tullio MR, Sacco RL, Mann DL, Levin B, Pullicino PM, Freudenberger RS, Teerlink JR, Mohr JP, Labovitz AJ, Lip GY, Estol CJ, Lok DJ, Ponikowski P, Anker SD, Thompson JL, Homma S. Cognitive function in ambulatory patients with systolic heart failure: insights from the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial. PLoS One. 2014; 9(11):e113447. PMID: 25426862.
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    31. Pullicino PM, Qian M, Sacco RL, Freudenberger R, Graham S, Teerlink JR, Mann D, Di Tullio MR, Ponikowski P, Lok DJ, Anker SD, Lip GY, Estol CJ, Levin B, Mohr JP, Thompson JL, Homma S. Recurrent stroke in the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial. Cerebrovasc Dis. 2014; 38(3):176-81. PMID: 25300706.
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    32. Qui?ones JN, Cox D, Smolinski WJ, Maksimik CA, Coassolo KM, Freudenberger R. Pregnancy in women after coronary revascularization. Obstet Med. 2014 Dec; 7(4):168-70. PMID: 27512447.
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    33. Pullicino PM, Thompson JL, Sacco RL, Sanford AR, Qian M, Teerlink JR, Haddad H, Diek M, Freudenberger RS, Labovitz AJ, Di Tullio MR, Lok DJ, Ponikowski P, Anker SD, Graham S, Mann DL, Mohr JP, Homma S. Stroke in heart failure in sinus rhythm: the Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction trial. Cerebrovasc Dis. 2013; 36(1):74-8. PMID: 23921215.
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    34. Homma S, Thompson JL, Sanford AR, Mann DL, Sacco RL, Levin B, Pullicino PM, Freudenberger RS, Teerlink JR, Graham S, Mohr JP, Massie BM, Labovitz AJ, Di Tullio MR, Gabriel AP, Lip GY, Estol CJ, Lok DJ, Ponikowski P, Anker SD. Benefit of warfarin compared with aspirin in patients with heart failure in sinus rhythm: a subgroup analysis of WARCEF, a randomized controlled trial. Circ Heart Fail. 2013 Sep 01; 6(5):988-97. PMID: 23881846.
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    35. Redeker NS, Adams L, Berkowitz R, Blank L, Freudenberger R, Gilbert M, Walsleben J, Zucker MJ, Rapoport D. Nocturia, sleep and daytime function in stable heart failure. J Card Fail. 2012 Jul; 18(7):569-75. PMID: 22748491.
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    36. Homma S, Thompson JL, Pullicino PM, Levin B, Freudenberger RS, Teerlink JR, Ammon SE, Graham S, Sacco RL, Mann DL, Mohr JP, Massie BM, Labovitz AJ, Anker SD, Lok DJ, Ponikowski P, Estol CJ, Lip GY, Di Tullio MR, Sanford AR, Mejia V, Gabriel AP, del Valle ML, Buchsbaum R. Warfarin and aspirin in patients with heart failure and sinus rhythm. N Engl J Med. 2012 May 17; 366(20):1859-69. PMID: 22551105.
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    37. Shariff N, Aleem A, Levin V, Desai RV, Nanda S, Martinez MW, Smith SJ, Freudenberger R. Venous thromboembolism in patients with heart failure: in-hospital and chronic use of anti-coagulants for prevention. Recent Pat Cardiovasc Drug Discov. 2012 Apr; 7(1):53-8. PMID: 22250920.
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    38. Shariff N, Aleem A, Levin V, Singh M, Islam N, Freudenberger R. Atrial fibrillation in patients with heart failure: Role of catheter ablation therapies. Exp Clin Cardiol. 2012; 17(4):237-42. PMID: 23592943.
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    39. Shariff N, Aleem A, Jacobs LE, Cutitta C, Siddique SM, Martinez MW, Matsumura ME, Freudenberger R. Atrial fibrillation following cardiac surgery: established and emerging strategies of prevention. Recent Pat Cardiovasc Drug Discov. 2011 Sep; 6(3):168-74. PMID: 21834770.
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    40. Shaaraoui M, Freudenberger R, Levin V, Marchlinski FE. Suppression of ventricular tachycardia with dronedarone: a case report. J Cardiovasc Electrophysiol. 2011 Feb; 22(2):201-2. PMID: 20550612.
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    41. Nanda S, Levin V, Martinez MW, Freudenberger R. Ranolazine--treatment of ventricular tachycardia and symptomatic ventricular premature beats in ischemic cardiomyopathy. Pacing Clin Electrophysiol. 2010 Dec; 33(12):e119-20. PMID: 20345626.
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    42. Redeker NS, Muench U, Zucker MJ, Walsleben J, Gilbert M, Freudenberger R, Chen M, Campbell D, Blank L, Berkowitz R, Adams L, Rapoport DM. Sleep disordered breathing, daytime symptoms, and functional performance in stable heart failure. Sleep. 2010 Apr; 33(4):551-60. PMID: 20394325.
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    43. Freudenberger RS, Schumaecker MM, Homma S. What is the appropriate approach to prevention of thromboembolism in heart failure? Thromb Haemost. 2010 Mar; 103(3):489-95. PMID: 20024492.
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    44. Rich DQ, Freudenberger RS, Ohman-Strickland P, Cho Y, Kipen HM. Right heart pressure increases after acute increases in ambient particulate concentration. Environ Health Perspect. 2008 Sep; 116(9):1167-71. PMID: 18795158.
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    45. Hare JM, Mangal B, Brown J, Fisher C, Freudenberger R, Colucci WS, Mann DL, Liu P, Givertz MM, Schwarz RP. Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study. J Am Coll Cardiol. 2008 Jun 17; 51(24):2301-9. PMID: 18549913.
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    46. Ahnert AM, Freudenberger RS. What do we know about anticoagulation in patients with heart failure? Curr Opin Cardiol. 2008 May; 23(3):228-32. PMID: 18382211.
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    47. Freudenberger R, Aaron M, Krueger S, Labeau M, Kleckner K, Klepfer RN. Acute electromechanical effects of atrioventricular coupled pacing in patients with heart failure. J Card Fail. 2008 Feb; 14(1):35-40. PMID: 18226771.
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    48. Skotzko CE, Vrinceanu A, Krueger L, Freudenberger R. Alcohol use and congestive heart failure: incidence, importance, and approaches to improved history taking. Heart Fail Rev. 2009 Mar; 14(1):51-5. PMID: 18034302.
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    49. Freudenberger RS, Wilson AC, Kostis JB. Comparison of rate versus rhythm control for atrial fibrillation in patients with left ventricular dysfunction (from the AFFIRM Study). Am J Cardiol. 2007 Jul 15; 100(2):247-52. PMID: 17631079.
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    50. Naik SD, Freudenberger RS. Beta-blocker contraindications: are there patients or situations where use is inappropriate? Curr Heart Fail Rep. 2007 Jun; 4(2):93-8. PMID: 17521501.
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    51. Freudenberger RS, Hellkamp AS, Halperin JL, Poole J, Anderson J, Johnson G, Mark DB, Lee KL, Bardy GH. Risk of thromboembolism in heart failure: an analysis from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT). Circulation. 2007 May 22; 115(20):2637-41. PMID: 17485579.
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    52. Freudenberger RS, Halperin JL. Should we use anticoagulation for patients with chronic heart failure? Nat Clin Pract Cardiovasc Med. 2006 Nov; 3(11):580-1. PMID: 17063158.
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    53. Ramasamy R, Hildebrandt T, O'Hea E, Patel M, Clemow L, Freudenberger R, Skotzko C. Psychological and social factors that correlate with dyspnea in heart failure. Psychosomatics. 2006 Sep-Oct; 47(5):430-4. PMID: 16959932.
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    54. Pullicino P, Thompson JL, Barton B, Levin B, Graham S, Freudenberger RS. Warfarin versus aspirin in patients with reduced cardiac ejection fraction (WARCEF): rationale, objectives, and design. J Card Fail. 2006 Feb; 12(1):39-46. PMID: 16500579.
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    55. Freudenberger R. A call to disarm: is malignancy higher in post-transplant patients? J Heart Lung Transplant. 2006 Mar; 25(3):368-9. PMID: 16507437.
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    56. Freudenberger RS, Massie BM. Silent cerebral infarction in heart failure: vascular or thromboembolic? J Card Fail. 2005 Sep; 11(7):490-1. PMID: 16198242.
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    57. Freudenberger RS, Wilson AC, Lawrence-Nelson J, Hare JM, Kostis JB. Permanent pacing is a risk factor for the development of heart failure. Am J Cardiol. 2005 Mar 01; 95(5):671-4. PMID: 15721119.
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    58. Kostis JB, Wilson AC, Freudenberger RS, Cosgrove NM, Pressel SL, Davis BR. Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes. Am J Cardiol. 2005 Jan 01; 95(1):29-35. PMID: 15619390.
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    59. Freudenberger R, Cahn SC, Skotzko C. Influence of age, gender, and race on depression in heart failure patients. J Am Coll Cardiol. 2004 Dec 07; 44(11):2254-5; author reply 2255-6. PMID: 15582328.
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    60. Freudenberger RS, Schwarz RP, Brown J, Moore A, Mann D, Givertz MM, Colucci WS, Hare JM. Rationale, design and organisation of an efficacy and safety study of oxypurinol added to standard therapy in patients with NYHA class III - IV congestive heart failure. Expert Opin Investig Drugs. 2004 Nov; 13(11):1509-16. PMID: 15500398.
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    61. Vasseur BG, Anderson MB, Freudenberger RS. Anomalous coronary artery in a transplanted heart: a technical modification. J Heart Lung Transplant. 2004 Aug; 23(8):1008-9. PMID: 15312832.
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    62. Freudenberger RS, Boruchoff SE, Anderson MB. Policies of U.S. heart transplant programs regarding transplantation of human immunodeficiency-positive patients. J Heart Lung Transplant. 2004 Jun; 23(6):785. PMID: 15366446.
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    63. Freudenberger R, Sikora JA, Fisher M, Wilson A, Gold M. Electrocardiogram and clinical characteristics of patients referred for cardiac transplantation: implications for pacing in heart failure. Clin Cardiol. 2004 Mar; 27(3):151-3. PMID: 15049383.
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    64. Naik SD, Freudenberger RS. Ephedra-associated cardiomyopathy. Ann Pharmacother. 2004 Mar; 38(3):400-3. PMID: 14742827.
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    65. Freudenberger RS, Carson JL. Is there an optimal hemoglobin value in the cardiac intensive care unit? Curr Opin Crit Care. 2003 Oct; 9(5):356-61. PMID: 14508147.
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