Thomas Jefferson University

Charles Antzelevitch

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19023
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Burashnikov A, Antzelevitch C. The efficacy of INa block to cardiovert atrial fibrillation is enhanced by inhibition of IK1. J Cardiovasc Pharmacol. 2024 Jul 29. PMID: 39115816.
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    2. Duan HY, Barajas-Martinez H, Antzelevitch C, Hu D. The potential anti-arrhythmic effect of SGLT2 inhibitors. Cardiovasc Diabetol. 2024 07 15; 23(1):252. PMID: 39010053.
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    3. Zhang ZH, Barajas-Martinez H, Jiang H, Huang CX, Antzelevitch C, Xia H, Hu D. Gene and stem cell therapy for inherited cardiac arrhythmias. Pharmacol Ther. 2024 Apr; 256:108596. PMID: 38301770.
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    4. Burashnikov A, Di Diego JM, Patocskai B, Echt DS, Belardinelli L, Antzelevitch C. Effect of Flecainide and Ibutilide Alone and in Combination to Terminate and Prevent Recurrence of Atrial Fibrillation. Circ Arrhythm Electrophysiol. 2023 Dec 26; e012454. PMID: 38146652.
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    5. Huang Y, Wang LL, Liu ZB, Chen C, Ren X, Luo AT, Ma JH, Antzelevitch C, Barajas-Mart?nez H, Hu D. Underlying mechanism of atrial fibrillation-associated Nppa-I137T mutation and cardiac effect of potential drug therapy. Heart Rhythm. 2024 02; 21(2):184-196. PMID: 37924963.
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    6. Burashnikov A, Antzelevitch C. Mild elevation of extracellular potassium greatly potentiates the effect of sodium channel block to cardiovert atrial fibrillation: The Lankenau approach. Heart Rhythm. 2023 May 09. PMID: 37169158.
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    7. Di Diego JM, Barajas-Martinez H, Cox R, Robinson VM, Jung J, Fouda M, Patocskai B, Abdelsayed M, Ruben PC, Antzelevitch C. Mechanisms underlying the antiarrhythmic effect of ARumenamide-787 in experimental models of the J wave syndromes and hypothermia. PLoS One. 2023; 18(5):e0281977. PMID: 37159454.
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    8. Hasdemir C, Kocabas U, Kilic S, Kose S, Kilic S, Gunduz R, Ulucan C, Yagmur B, Sahin H, Celen C, Orman MN, Yuksel A, Aydin M, Payzin S, Juang JJ, Antzelevitch C. Premature Atrial Contraction-Induced Cardiomyopathy: Recognition of a Distinct Phenotype of Arrhythmia-Induced Cardiomyopathy in Humans. Am J Cardiol. 2023 06 15; 197:65-67. PMID: 37164875.
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    9. Hu D, Barajas-Martinez H, Zhang ZH, Duan HY, Zhao QY, Bao MW, Du YM, Burashnikov A, Monasky MM, Pappone C, Huang CX, Antzelevitch C, Jiang H. Advances in basic and translational research in atrial fibrillation. Philos Trans R Soc Lond B Biol Sci. 2023 Jun 19; 378(1879):20220174. PMID: 37122214.
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    10. Zeng B, Zhang X, Schimpf R, Powers A, Glikson M, Antzelevitch C, Hu D, Barajas-Martinez H. Functional identification of hot-spot mutations in cardiac calcium channel genes associated with the J wave syndromes. Philos Trans R Soc Lond B Biol Sci. 2023 06 19; 378(1879):20220286. PMID: 37122210.
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    11. Chen GX, Barajas-Mart?nez H, Ciconte G, Wu CI, Monasky MM, Xia H, Li B, Capra JA, Guo K, Zhang ZH, Chen X, Yang B, Jiang H, Tse G, Mak CM, Aizawa Y, Gollob MH, Antzelevitch C, Wilde AAM, Pappone C, Hu D. Clinical characteristics and electrophysiologic properties of SCN5A variants in fever-induced Brugada syndrome. EBioMedicine. 2023 Jan; 87:104388. PMID: 36516610.
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    12. Ye D, Zhou W, Hamrick SK, Tester DJ, Kim CSJ, Barajas-Martinez H, Hu D, Giudicessi JR, Antzelevitch C, Ackerman MJ. Acacetin, a Potent Transient Outward Current Blocker, May Be a Novel Therapeutic for KCND3-Encoded Kv4.3 Gain-of-Function-Associated J-Wave Syndromes. Circ Genom Precis Med. 2022 Oct; 15(5):e003238. PMID: 35861988.
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    13. Hasdemir C, Sahin H, Duran G, Orman MN, Kocabas U, Payzin S, Aydin M, Antzelevitch C. Electrocardiographic variables associated with underlying Brugada syndrome or drug-induced Type 1 Brugada pattern in patients with slow/fast atrioventricular nodal reentrant tachycardia. J Arrhythm. 2022 Aug; 38(4):633-641. PMID: 35936048.
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    14. Barc J, Tadros R, Glinge C, Chiang DY, Jouni M, Simonet F, Jurgens SJ, Baudic M, Nicastro M, Potet F, Offerhaus JA, Walsh R, Choi SH, Verkerk AO, Mizusawa Y, Anys S, Minois D, Arnaud M, Duchateau J, Wijeyeratne YD, Muir A, Papadakis M, Castelletti S, Torchio M, Ortu?o CG, Lacunza J, Giachino DF, Cerrato N, Martins RP, Campuzano O, Van Dooren S, Thollet A, Kyndt F, Mazzanti A, Cl?menty N, Bisson A, Corveleyn A, Stallmeyer B, Dittmann S, Saenen J, No?l A, Honarbakhsh S, Rudic B, Marzak H, Rowe MK, Federspiel C, Le Page S, Placide L, Milhem A, Barajas-Martinez H, Beckmann BM, Krapels IP, Steinfurt J, Winkel BG, Jabbari R, Shoemaker MB, Boukens BJ, ?koric-Milosavljevic D, Bikker H, Manevy F, Lichtner P, Ribas?s M, Meitinger T, M?ller-Nurasyid M, Veldink JH, van den Berg LH, Van Damme P, Cusi D, Lanzani C, Rigade S, Charpentier E, Baron E, Bonnaud S, Lecointe S, Donnart A, Le Marec H, Chatel S, Karakachoff M, B?zieau S, London B, Tfelt-Hansen J, Roden D, Odening KE, Cerrone M, Chinitz LA, Volders PG, van de Berg MP, Laurent G, Faivre L, Antzelevitch C, K??b S, Arnaout AA, Dupuis JM, Pasquie JL, Billon O, Roberts JD, Jesel L, Borggrefe M, Lambiase PD, Mansourati J, Loeys B, Leenhardt A, Guicheney P, Maury P, Schulze-Bahr E, Robyns T, Breckpot J, Babuty D, Priori SG, Napolitano C, de Asmundis C, Brugada P, Brugada R, Arbelo E, Brugada J, Mabo P, Behar N, Giustetto C, Molina MS, Gimeno JR, Hasdemir C, Schwartz PJ, Crotti L, McKeown PP, Sharma S, Behr ER, Haissaguerre M, Sacher F, Rooryck C, Tan HL, Remme CA, Postema PG, Delmar M, Ellinor PT, Lubitz SA, Gourraud JB, Tanck MW, George AL, MacRae CA, Burridge PW, Dina C, Probst V, Wilde AA, Schott JJ, Redon R, Bezzina CR. Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nat Genet. 2022 May; 54(5):735. PMID: 35474365.
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    15. Robinson VM, Di Diego JM, Bowes MT, Kowey PR, Antzelevitch C, Venetucci L. Increased susceptibility to ventricular arrhythmia at low-normal and moderately low levels of extracellular potassium in catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm. 2022 08; 19(8):1389-1391. PMID: 35429650.
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    16. Barc J, Tadros R, Glinge C, Chiang DY, Jouni M, Simonet F, Jurgens SJ, Baudic M, Nicastro M, Potet F, Offerhaus JA, Walsh R, Choi SH, Verkerk AO, Mizusawa Y, Anys S, Minois D, Arnaud M, Duchateau J, Wijeyeratne YD, Muir A, Papadakis M, Castelletti S, Torchio M, Ortu?o CG, Lacunza J, Giachino DF, Cerrato N, Martins RP, Campuzano O, Van Dooren S, Thollet A, Kyndt F, Mazzanti A, Cl?menty N, Bisson A, Corveleyn A, Stallmeyer B, Dittmann S, Saenen J, No?l A, Honarbakhsh S, Rudic B, Marzak H, Rowe MK, Federspiel C, Le Page S, Placide L, Milhem A, Barajas-Martinez H, Beckmann BM, Krapels IP, Steinfurt J, Winkel BG, Jabbari R, Shoemaker MB, Boukens BJ, ?koric-Milosavljevic D, Bikker H, Manevy F, Lichtner P, Ribas?s M, Meitinger T, M?ller-Nurasyid M, Veldink JH, van den Berg LH, Van Damme P, Cusi D, Lanzani C, Rigade S, Charpentier E, Baron E, Bonnaud S, Lecointe S, Donnart A, Le Marec H, Chatel S, Karakachoff M, B?zieau S, London B, Tfelt-Hansen J, Roden D, Odening KE, Cerrone M, Chinitz LA, Volders PG, van de Berg MP, Laurent G, Faivre L, Antzelevitch C, K??b S, Arnaout AA, Dupuis JM, Pasquie JL, Billon O, Roberts JD, Jesel L, Borggrefe M, Lambiase PD, Mansourati J, Loeys B, Leenhardt A, Guicheney P, Maury P, Schulze-Bahr E, Robyns T, Breckpot J, Babuty D, Priori SG, Napolitano C, de Asmundis C, Brugada P, Brugada R, Arbelo E, Brugada J, Mabo P, Behar N, Giustetto C, Molina MS, Gimeno JR, Hasdemir C, Schwartz PJ, Crotti L, McKeown PP, Sharma S, Behr ER, Haissaguerre M, Sacher F, Rooryck C, Tan HL, Remme CA, Postema PG, Delmar M, Ellinor PT, Lubitz SA, Gourraud JB, Tanck MW, George AL, MacRae CA, Burridge PW, Dina C, Probst V, Wilde AA, Schott JJ, Redon R, Bezzina CR. Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nat Genet. 2022 03; 54(3):232-239. PMID: 35210625.
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    17. Robinson VM, Alsalahat I, Freeman S, Antzelevitch C, Barajas-Martinez H, Venetucci L. A carvedilol analogue, VK-II-86, prevents hypokalaemia-induced ventricular arrhythmia through novel multi-channel effects. Br J Pharmacol. 2022 06; 179(11):2713-2732. PMID: 34877651.
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    18. Huang Y, Chen XM, Barajas-Martinez H, Jiang H, Antzelevitch C, Hu D. Common variants in SCN10A gene associated with Brugada syndrome. Hum Mol Genet. 2021 12 27; 31(2):157-165. PMID: 34312669.
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    19. Zhang ZH, Barajas-Mart?nez H, Xia H, Li B, Capra JA, Clatot J, Chen GX, Chen X, Yang B, Jiang H, Tse G, Aizawa Y, Gollob MH, Scheinman M, Antzelevitch C, Hu D. Distinct Features of Probands With Early Repolarization and Brugada Syndromes Carrying SCN5A Pathogenic Variants. J Am Coll Cardiol. 2021 10 19; 78(16):1603-1617. PMID: 34649698.
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    20. Burashnikov A, Barajas-Martinez H, Cox R, Demitrack MA, Fossler MJ, Kramer M, Kleiman RB, Kowey P, Antzelevitch C. Intracellular uptake of agents that block the hERG channel can confound the assessment of QT interval prolongation and arrhythmic risk. Heart Rhythm. 2021 12; 18(12):2177-2186. PMID: 34481984.
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    21. Antzelevitch C, Di Diego JM. J wave syndromes: What's new? Trends Cardiovasc Med. 2022 08; 32(6):350-363. PMID: 34256120.
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    22. Chen X, Barajas-Mart?nez H, Xia H, Zhang Z, Chen G, Yang B, Jiang H, Antzelevitch C, Hu D. Clinical and Functional Genetic Characterization of the Role of Cardiac Calcium Channel Variants in the Early Repolarization Syndrome. Front Cardiovasc Med. 2021; 8:680819. PMID: 34222376.
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    23. Sarica AS, Bor S, Orman MN, Barajas-Martinez H, Juang JJ, Antzelevitch C, Hasdemir C. Frequency of Irritable Bowel Syndrome in Patients with Brugada Syndrome and Drug-Induced Type 1 Brugada Pattern. Am J Cardiol. 2021 07 15; 151:51-56. PMID: 34034907.
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    24. Sarcon A, Hsia H, Postema PG, Wilde AAM, Patocskai B, Di Diego JM, Antzelevitch C, Scheinman M. Fractionated Epicardial Electrograms: Implication for Mechanism of the Brugada Pattern. JACC Clin Electrophysiol. 2021 02; 7(2):258-270. PMID: 33602410.
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    25. Di Diego JM, Patocskai B, Barajas-Martinez H, Borb?th V, Ackerman MJ, Burashnikov A, Clatot J, Li GR, Robinson VM, Hu D, Antzelevitch C. Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes. PLoS One. 2020; 15(11):e0242747. PMID: 33232375.
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    26. Hasdemir C, Gokcay F, Orman MN, Kocabas U, Payzin S, Sahin H, Nyholt DR, Antzelevitch C. Recognition and clinical implications of high prevalence of migraine in patients with Brugada syndrome and drug-induced type 1 Brugada pattern. J Cardiovasc Electrophysiol. 2020 12; 31(12):3311-3317. PMID: 33058326.
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    27. Walsh R, Lahrouchi N, Tadros R, Kyndt F, Glinge C, Postema PG, Amin AS, Nannenberg EA, Ware JS, Whiffin N, Mazzarotto F, ?koric-Milosavljevic D, Krijger C, Arbelo E, Babuty D, Barajas-Martinez H, Beckmann BM, B?zieau S, Bos JM, Breckpot J, Campuzano O, Castelletti S, Celen C, Clauss S, Corveleyn A, Crotti L, Dagradi F, de Asmundis C, Denjoy I, Dittmann S, Ellinor PT, Ortu?o CG, Giustetto C, Gourraud JB, Hazeki D, Horie M, Ishikawa T, Itoh H, Kaneko Y, Kanters JK, Kimoto H, Kotta MC, Krapels IPC, Kurabayashi M, Lazarte J, Leenhardt A, Loeys BL, Lundin C, Makiyama T, Mansourati J, Martins RP, Mazzanti A, M?rner S, Napolitano C, Ohkubo K, Papadakis M, Rudic B, Molina MS, Sacher F, Sahin H, Sarquella-Brugada G, Sebastiano R, Sharma S, Sheppard MN, Shimamoto K, Shoemaker MB, Stallmeyer B, Steinfurt J, Tanaka Y, Tester DJ, Usuda K, van der Zwaag PA, Van Dooren S, Van Laer L, Winbo A, Winkel BG, Yamagata K, Zumhagen S, Volders PGA, Lubitz SA, Antzelevitch C, Platonov PG, Odening KE, Roden DM, Roberts JD, Skinner JR, Tfelt-Hansen J, van den Berg MP, Olesen MS, Lambiase PD, Borggrefe M, Hayashi K, Rydberg A, Nakajima T, Yoshinaga M, Saenen JB, K??b S, Brugada P, Robyns T, Giachino DF, Ackerman MJ, Brugada R, Brugada J, Gimeno JR, Hasdemir C, Guicheney P, Priori SG, Schulze-Bahr E, Makita N, Schwartz PJ, Shimizu W, Aiba T, Schott JJ, Redon R, Ohno S, Probst V, Behr ER, Barc J, Bezzina CR. Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls. Genet Med. 2021 01; 23(1):47-58. PMID: 32893267.
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    28. Barajas-Martinez H, Smith M, Hu D, Goodrow RJ, Puleo C, Hasdemir C, Antzelevitch C, Pfeiffer R, Treat JA, Cordeiro JM. Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes. Stem Cells Int. 2020; 2020:8842398. PMID: 32952569.
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    29. Burashnikov A, Barajas-Martinez H, Hu D, Robinson VM, Grunnet M, Antzelevitch C. The Small Conductance Calcium-Activated Potassium Channel Inhibitors NS8593 and UCL1684 Prevent the Development of Atrial Fibrillation Through Atrial-Selective Inhibition of Sodium Channel Activity. J Cardiovasc Pharmacol. 2020 08; 76(2):164-172. PMID: 32453071.
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    30. Clatot J, Neyroud N, Cox R, Souil C, Huang J, Guicheney P, Antzelevitch C. Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies. Int J Mol Sci. 2020 Jul 17; 21(14). PMID: 32709127.
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    31. Schwartz PJ, Ackerman MJ, Antzelevitch C, Bezzina CR, Borggrefe M, Cuneo BF, Wilde AAM. Inherited cardiac arrhythmias. Nat Rev Dis Primers. 2020 07 16; 6(1):58. PMID: 32678103.
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    32. Juang JJ, Binda A, Lee SJ, Hwang JJ, Chen WJ, Liu YB, Lin LY, Yu CC, Ho LT, Huang HC, Chen CJ, Lu TP, Lai LC, Yeh SS, Lai LP, Chuang EY, Rivolta I, Antzelevitch C. GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death. EBioMedicine. 2020 Jul; 57:102843. PMID: 32645615.
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    33. Lahrouchi N, Tadros R, Crotti L, Mizusawa Y, Postema PG, Beekman L, Walsh R, Hasegawa K, Barc J, Ernsting M, Turkowski KL, Mazzanti A, Beckmann BM, Shimamoto K, Diamant UB, Wijeyeratne YD, Kucho Y, Robyns T, Ishikawa T, Arbelo E, Christiansen M, Winbo A, Jabbari R, Lubitz SA, Steinfurt J, Rudic B, Loeys B, Shoemaker MB, Weeke PE, Pfeiffer R, Davies B, Andorin A, Hofman N, Dagradi F, Pedrazzini M, Tester DJ, Bos JM, Sarquella-Brugada G, Campuzano ?, Platonov PG, Stallmeyer B, Zumhagen S, Nannenberg EA, Veldink JH, van den Berg LH, Al-Chalabi A, Shaw CE, Shaw PJ, Morrison KE, Andersen PM, M?ller-Nurasyid M, Cusi D, Barlassina C, Galan P, Lathrop M, Munter M, Werge T, Ribas?s M, Aung T, Khor CC, Ozaki M, Lichtner P, Meitinger T, van Tintelen JP, Hoedemaekers Y, Denjoy I, Leenhardt A, Napolitano C, Shimizu W, Schott JJ, Gourraud JB, Makiyama T, Ohno S, Itoh H, Krahn AD, Antzelevitch C, Roden DM, Saenen J, Borggrefe M, Odening KE, Ellinor PT, Tfelt-Hansen J, Skinner JR, van den Berg MP, Olesen MS, Brugada J, Brugada R, Makita N, Breckpot J, Yoshinaga M, Behr ER, Rydberg A, Aiba T, K??b S, Priori SG, Guicheney P, Tan HL, Newton-Cheh C, Ackerman MJ, Schwartz PJ, Schulze-Bahr E, Probst V, Horie M, Wilde AA, Tanck MWT, Bezzina CR. Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome. Circulation. 2020 07 28; 142(4):324-338. PMID: 32429735.
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    34. Hu D, Hu D, Liu L, Barr D, Liu Y, Balderrabano-Saucedo N, Wang B, Zhu F, Xue Y, Wu S, Song B, McManus H, Murphy K, Loes K, Adler A, Monserrat L, Antzelevitch C, Gollob MH, Elliott PM, Barajas-Martinez H. Identification, clinical manifestation and structural mechanisms of mutations in AMPK associated cardiac glycogen storage disease. EBioMedicine. 2020 Apr; 54:102723. PMID: 32259713.
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    35. Musa H, Marcou CA, Herron TJ, Makara MA, Tester DJ, O'Connell RP, Rosinski B, Guerrero-Serna G, Milstein ML, Monteiro da Rocha A, Ye D, Crotti L, Nesterenko VV, Castelletti S, Torchio M, Kotta MC, Dagradi F, Antzelevitch C, Mohler PJ, Schwartz PJ, Ackerman MJ, Anumonwo JM. Abnormal myocardial expression of SAP97 is associated with arrhythmogenic risk. Am J Physiol Heart Circ Physiol. 2020 06 01; 318(6):H1357-H1370. PMID: 32196358.
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    36. Antzelevitch C. Tpeak-tend interval as a marker of arrhythmic risk in early repolarization syndrome. J Cardiovasc Electrophysiol. 2019 10; 30(10):2106-2107. PMID: 31432584.
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    37. Nof E, Vysochek L, Meisel E, Burashnikov E, Antzelevitch C, Clatot J, Beinart R, Luria D, Glikson M, Oz S. Mutations in NaV1.5 Reveal Calcium-Calmodulin Regulation of Sodium Channel. Front Physiol. 2019; 10:700. PMID: 31231243.
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    38. Argenziano MA, Doss MX, Tabler M, Sachinidis A, Antzelevitch C. Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis. PLoS One. 2019; 14(5):e0216928. PMID: 31083689.
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    39. Li X, Sacher F, Kusano KF, Barajas-Martinez H, Liu N, Li Y, Gao Y, Liu T, Shang H, Antzelevitch C, Hu D, Xing Y. Pooled Analysis of Risk Stratification of Spontaneous Type 1 Brugada ECG: Focus on the Influence of Gender and EPS. Front Physiol. 2018; 9:1951. PMID: 30766491.
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    40. Antzelevitch C, Di Diego JM. Reply to the Editor- Tpeak-Tend is alive and well. Heart Rhythm. 2019 06; 16(6):e49-e50. PMID: 30682432.
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    41. Antzelevitch C, Di Diego JM. Tpeak-Tend interval as a marker of arrhythmic risk. Heart Rhythm. 2019 06; 16(6):954-955. PMID: 30660560.
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    42. Chen CJ, Lu TP, Lin LY, Liu YB, Ho LT, Huang HC, Lai LP, Hwang JJ, Yeh SS, Wu CK, Juang JJ, Antzelevitch C. Impact of Ancestral Differences and Reassessment of the Classification of Previously Reported Pathogenic Variants in Patients With Brugada Syndrome in the Genomic Era: A SADS-TW BrS Registry. Front Genet. 2018; 9:680. PMID: 30662450.
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    43. Di Diego JM, Antzelevitch C. Inferolateral J-wave syndromes: A reflection of abnormal repolarization, depolarization, or both? Heart Rhythm. 2019 05; 16(5):791-792. PMID: 30465906.
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    44. Sicouri S, Belardinelli L, Antzelevitch C. Effect of autonomic influences to induce triggered activity in muscular sleeves extending into the coronary sinus of the canine heart and its suppression by ranolazine. J Cardiovasc Electrophysiol. 2019 02; 30(2):230-238. PMID: 30302862.
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    45. Burashnikov A, Antzelevitch C. Is extensive atrial fibrosis in the setting of heart failure associated with a reduced atrial fibrillation burden? Pacing Clin Electrophysiol. 2018 10; 41(10):1289-1297. PMID: 30152017.
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    46. Yoon N, Patocskai B, Antzelevitch C. Epicardial Substrate as a Target for Radiofrequency Ablation in an Experimental Model of Early Repolarization Syndrome. Circ Arrhythm Electrophysiol. 2018 09; 11(9):e006511. PMID: 30354293.
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    47. Castro Hevia J, Dorantes Sanchez M, Martinez Lopez F, Casta?eda Chirino O, Falcon Rodriguez R, Puga Bravo M, de Zayas Galguera J, Antzelevitch C. Multiple serial ECGs aid with the diagnosis and prognosis of Brugada syndrome. Int J Cardiol. 2019 Feb 15; 277:130-135. PMID: 30195842.
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    48. Sicouri S, Antzelevitch C. Mechanisms Underlying the Actions of Antidepressant and Antipsychotic Drugs That Cause Sudden Cardiac Arrest. Arrhythm Electrophysiol Rev. 2018 Aug; 7(3):199-209. PMID: 30416734.
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    49. Hasdemir C, Juang JJ, Kose S, Kocabas U, Orman MN, Payzin S, Sahin H, Celen C, Ozcan EE, Chen CJ, Gunduz R, Turan OE, Senol O, Burashnikov E, Antzelevitch C. Coexistence of atrioventricular accessory pathways and drug-induced type 1 Brugada pattern. Pacing Clin Electrophysiol. 2018 09; 41(9):1078-1092. PMID: 29953624.
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    50. Di Diego JM, Antzelevitch C. J wave syndromes as a cause of malignant cardiac arrhythmias. Pacing Clin Electrophysiol. 2018 07; 41(7):684-699. PMID: 29870068.
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    51. Argenziano M, Antzelevitch C. Recent advances in the treatment of Brugada syndrome. Expert Rev Cardiovasc Ther. 2018 Jun; 16(6):387-404. PMID: 29757020.
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    52. Kawada S, Morita H, Antzelevitch C, Morimoto Y, Nakagawa K, Watanabe A, Nishii N, Nakamura K, Ito H. Shanghai Score System for Diagnosis of Brugada Syndrome: Validation of the Score System and System and Reclassification of the Patients. JACC Clin Electrophysiol. 2018 06; 4(6):724-730. PMID: 29929664.
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    53. Savio-Galimberti E, Argenziano M, Antzelevitch C. Cardiac Arrhythmias Related to Sodium Channel Dysfunction. Handb Exp Pharmacol. 2018; 246:331-354. PMID: 28965168.
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    54. Antzelevitch C, Di Diego JM, Argenziano M. Tpeak-Tend as a predictor of ventricular arrhythmogenesis. Int J Cardiol. 2017 12 15; 249:75-76. PMID: 29121761.
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    55. Antzelevitch C, Viskin S. Should theophylline be added to the J wave syndrome therapeutic armamentarium? Pacing Clin Electrophysiol. 2018 05; 41(5):439-440. PMID: 29148067.
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    56. Viskin S, Havakuk O, Antzelevitch C, Rosso R. Theophylline: The forgotten antiarrhythmic drug? now for malignant early repolarization. Pacing Clin Electrophysiol. 2018 05; 41(5):441-443. PMID: 29148055.
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    57. Antzelevitch C, Patocskai B. Ajmaline-Induced Slowing of Conduction in the Right Ventricular Outflow Tract Cannot Account for ST Elevation in Patients With Type I Brugada ECG. Circ Arrhythm Electrophysiol. 2017 10; 10(10). PMID: 29038108.
      Citations:    
    58. Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, Gussak I, Hasdemir C, Horie M, Huikuri H, Ma C, Morita H, Nam GB, Sacher F, Shimizu W, Viskin S, Wilde AAM. J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. Europace. 2017 04 01; 19(4):665-694. PMID: 28431071.
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    59. Krych M, Biernacka EK, Poninska J, Kukla P, Filipecki A, Gajda R, Hasdemir C, Antzelevitch C, Kosiec A, Szperl M, Ploski R, Trusz-Gluza M, Mizia-Stec K, Hoffman P. Andersen-Tawil syndrome: Clinical presentation and predictors of symptomatic arrhythmias - Possible role of polymorphisms K897T in KCNH2 and H558R in SCN5A gene. J Cardiol. 2017 Nov; 70(5):504-510. PMID: 28336205.
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    60. Burashnikov A, Antzelevitch C. Effectiveness of Late INa Versus Peak INa Block in the Setting of Ventricular Fibrillation. Circ Arrhythm Electrophysiol. 2017 03; 10(3). PMID: 28314847.
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    61. Hu D, Li Y, Zhang J, Pfeiffer R, Gollob MH, Healey J, Harrell DT, Makita N, Abe H, Sun Y, Guo J, Zhang L, Yan G, Mah D, Walsh EP, Leopold HB, Giustetto C, Gaita F, Zienciuk-Krajka A, Mazzanti A, Priori SG, Antzelevitch C, Barajas-Martinez H. The Phenotypic Spectrum of a Mutation?Hotspot Responsible for the?Short QT Syndrome. JACC Clin Electrophysiol. 2017 07; 3(7):727-743. PMID: 29759541.
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    62. Patocskai B, Yoon N, Antzelevitch C. Mechanisms Underlying Epicardial Radiofrequency Ablation to Suppress Arrhythmogenesis in Experimental Models of Brugada Syndrome. JACC Clin Electrophysiol. 2017 04; 3(4):353-363. PMID: 28948234.
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    63. Chorin E, Hu D, Antzelevitch C, Hochstadt A, Belardinelli L, Zeltser D, Barajas-Martinez H, Rozovski U, Rosso R, Adler A, Benhorin J, Viskin S. Ranolazine for Congenital Long-QT Syndrome Type III: Experimental and Long-Term Clinical Data. Circ Arrhythm Electrophysiol. 2016 Oct; 9(10). PMID: 27733495.
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    64. Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, Gussak I, Hasdemir C, Horie M, Huikuri H, Ma C, Morita H, Nam GB, Sacher F, Shimizu W, Viskin S, Wilde AA. J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. J Arrhythm. 2016 Oct; 32(5):315-339. PMID: 27761155.
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    65. Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, Gussak I, Hasdemir C, Horie M, Huikuri H, Ma C, Morita H, Nam GB, Sacher F, Shimizu W, Viskin S, Wilde AA. J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. Heart Rhythm. 2016 10; 13(10):e295-324. PMID: 27423412.
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    66. Veltmann C, Barajas-Martinez H, Wolpert C, Borggrefe M, Schimpf R, Pfeiffer R, C?ceres G, Burashnikov E, Antzelevitch C, Hu D. Further Insights in the Most Common SCN5A Mutation Causing Overlapping Phenotype of Long QT Syndrome, Brugada Syndrome, and Conduction Defect. J Am Heart Assoc. 2016 07 05; 5(7). PMID: 27381756.
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    67. Enriquez A, Antzelevitch C, Bismah V, Baranchuk A. Atrial fibrillation in inherited cardiac channelopathies: From mechanisms to management. Heart Rhythm. 2016 09; 13(9):1878-84. PMID: 27291509.
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    68. Sutphin BS, Boczek NJ, Barajas-Mart?nez H, Hu D, Ye D, Tester DJ, Antzelevitch C, Ackerman MJ. Molecular and Functional Characterization of Rare CACNA1C Variants in Sudden Unexplained Death in the Young. Congenit Heart Dis. 2016 Dec; 11(6):683-692. PMID: 27218670.
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    69. Mizusawa Y, Morita H, Adler A, Havakuk O, Thollet A, Maury P, Wang DW, Hong K, Gandjbakhch E, Sacher F, Hu D, Amin AS, Lahrouchi N, Tan HL, Antzelevitch C, Probst V, Viskin S, Wilde AA. Prognostic significance of fever-induced Brugada syndrome. Heart Rhythm. 2016 07; 13(7):1515-20. PMID: 27033637.
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    70. Patocskai B, Barajas-Martinez H, Hu D, Gurabi Z, Koncz I, Antzelevitch C. Cellular and ionic mechanisms underlying the effects of cilostazol, milrinone, and isoproterenol to suppress arrhythmogenesis in an experimental model of early repolarization syndrome. Heart Rhythm. 2016 06; 13(6):1326-34. PMID: 26820510.
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    71. Sroubek J, Probst V, Mazzanti A, Delise P, Hevia JC, Ohkubo K, Zorzi A, Champagne J, Kostopoulou A, Yin X, Napolitano C, Milan DJ, Wilde A, Sacher F, Borggrefe M, Ellinor PT, Theodorakis G, Nault I, Corrado D, Watanabe I, Antzelevitch C, Allocca G, Priori SG, Lubitz SA. Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis. Circulation. 2016 Feb 16; 133(7):622-30. PMID: 26797467.
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    72. Hu D, Barajas-Mart?nez H, Burashnikov A, Panama BK, Cordeiro JM, Antzelevitch C. Mechanisms underlying atrial-selective block of sodium channels by Wenxin Keli: Experimental and theoretical analysis. Int J Cardiol. 2016 Mar 15; 207:326-34. PMID: 26820362.
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    73. Viskin S, Havakuk O, Antzelevitch C, Rosso R. Malignant early repolarization: It's the T-wave, stupid?. Heart Rhythm. 2016 Apr; 13(4):903-4. PMID: 26690063.
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    74. Xing Y, Hu D, Zhang T, Antzelevitch C. Traditional Chinese Medicine and Vascular Disease. Evid Based Complement Alternat Med. 2015; 2015:430818. PMID: 26576194.
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    75. Adler A, Rosso R, Chorin E, Havakuk O, Antzelevitch C, Viskin S. Risk stratification in Brugada syndrome: Clinical characteristics, electrocardiographic parameters, and auxiliary testing. Heart Rhythm. 2016 Jan; 13(1):299-310. PMID: 26341603.
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    76. Macfarlane PW, Antzelevitch C, Haissaguerre M, Huikuri HV, Potse M, Rosso R, Sacher F, Tikkanen JT, Wellens H, Yan GX. The Early Repolarization Pattern: A Consensus Paper. J Am Coll Cardiol. 2015 Jul 28; 66(4):470-7. PMID: 26205599.
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    77. Viskin S, Antzelevitch C, Rosso R. Call "the Cleaners": How to Treat Drug-Induced Torsades de Pointes. JACC Clin Electrophysiol. 2015 Aug; 1(4):323-325. PMID: 29759320.
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    78. Antzelevitch C, Patocskai B. Brugada Syndrome: Clinical, Genetic, Molecular, Cellular, and Ionic Aspects. Curr Probl Cardiol. 2016 Jan; 41(1):7-57. PMID: 26671757.
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    79. Hasdemir C, Payzin S, Kocabas U, Sahin H, Yildirim N, Alp A, Aydin M, Pfeiffer R, Burashnikov E, Wu Y, Antzelevitch C. High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia. Heart Rhythm. 2015 Jul; 12(7):1584-94. PMID: 25998140.
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    80. Patocskai B, Antzelevitch C. Novel Therapeutic Strategies for the Management of Ventricular Arrhythmias Associated with the Brugada Syndrome. Expert Opin Orphan Drugs. 2015; 3(6):633-651. PMID: 27559494.
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    81. Antzelevitch C, Yan GX. J-wave syndromes: Brugada and early repolarization syndromes. Heart Rhythm. 2015 Aug; 12(8):1852-66. PMID: 25869754.
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    82. Giustetto C, Scrocco C, Schimpf R, Maury P, Mazzanti A, Levetto M, Anttonen O, Dalmasso P, Cerrato N, Gribaudo E, Wolpert C, Giachino D, Antzelevitch C, Borggrefe M, Gaita F. Usefulness of exercise test in the diagnosis of short QT syndrome. Europace. 2015 Apr; 17(4):628-34. PMID: 25833882.
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    83. Burashnikov A, Di Diego JM, Goodrow RJ, Belardinelli L, Antzelevitch C. Atria are More Sensitive Than Ventricles to GS-458967-Induced Inhibition of Late Sodium Current. J Cardiovasc Pharmacol Ther. 2015 Sep; 20(5):501-8. PMID: 25652294.
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    84. Obeyesekere MN, Antzelevitch C, Krahn AD. Management of ventricular arrhythmias in suspected channelopathies. Circ Arrhythm Electrophysiol. 2015 Feb; 8(1):221-31. PMID: 25691556.
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    85. Betzenhauser MJ, Pitt GS, Antzelevitch C. Calcium Channel Mutations in Cardiac Arrhythmia Syndromes. Curr Mol Pharmacol. 2015; 8(2):133-42. PMID: 25981977.
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    86. Burashnikov A, Belardinelli L, Antzelevitch C. Inhibition of IKr potentiates development of atrial-selective INa block leading to effective suppression of atrial fibrillation. Heart Rhythm. 2015 Apr; 12(4):836-44. PMID: 25546810.
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    87. Boczek NJ, Miller EM, Ye D, Nesterenko VV, Tester DJ, Antzelevitch C, Czosek RJ, Ackerman MJ, Ware SM. Novel Timothy syndrome mutation leading to increase in CACNA1C window current. Heart Rhythm. 2015 Jan; 12(1):211-9. PMID: 25260352.
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    88. Hennessey JA, Boczek NJ, Jiang YH, Miller JD, Patrick W, Pfeiffer R, Sutphin BS, Tester DJ, Barajas-Martinez H, Ackerman MJ, Antzelevitch C, Kanter R, Pitt GS. A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis. PLoS One. 2014; 9(9):e106982. PMID: 25184293.
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    89. Hu D, Barajas-Mart?nez H, Pfeiffer R, Dezi F, Pfeiffer J, Buch T, Betzenhauser MJ, Belardinelli L, Kahlig KM, Rajamani S, DeAntonio HJ, Myerburg RJ, Ito H, Deshmukh P, Marieb M, Nam GB, Bhatia A, Hasdemir C, Ha?ssaguerre M, Veltmann C, Schimpf R, Borggrefe M, Viskin S, Antzelevitch C. Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome. J Am Coll Cardiol. 2014 Jul 08; 64(1):66-79. PMID: 24998131.
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    90. Burashnikov A, Di Diego JM, Barajas-Mart?nez H, Hu D, Zygmunt AC, Cordeiro JM, Moise NS, Kornreich BG, Belardinelli L, Antzelevitch C. Ranolazine effectively suppresses atrial fibrillation in the setting of heart failure. Circ Heart Fail. 2014 Jul; 7(4):627-33. PMID: 24874201.
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    91. T?l?men E, Giustetto C, Wolpert C, Maury P, Anttonen O, Probst V, Blanc JJ, Sbragia P, Scrocco C, Rudic B, Veltmann C, Sun Y, Gaita F, Antzelevitch C, Borggrefe M, Schimpf R. Reply to the Editor--PQ-segment depression in short QT syndrome patients: a novel marker for diagnosing short QT syndrome? Heart Rhythm. 2014 Jul; 11(7):e8. PMID: 24768854.
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    92. Sz?l T, Antzelevitch C. Abnormal repolarization as the basis for late potentials and fractionated electrograms recorded from epicardium in experimental models of Brugada syndrome. J Am Coll Cardiol. 2014 May 20; 63(19):2037-45. PMID: 24657694.
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    93. T?l?men E, Giustetto C, Wolpert C, Maury P, Anttonen O, Probst V, Blanc JJ, Sbragia P, Scrocco C, Rudic B, Veltmann C, Sun Y, Gaita F, Antzelevitch C, Borggrefe M, Schimpf R. PQ segment depression in patients with short QT syndrome: a novel marker for diagnosing short QT syndrome? Heart Rhythm. 2014 Jun; 11(6):1024-30. PMID: 24589867.
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    94. Di Diego JM, Antzelevitch C. Acute myocardial ischemia: cellular mechanisms underlying ST segment elevation. J Electrocardiol. 2014 Jul-Aug; 47(4):486-90. PMID: 24742586.
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    95. Gurabi Z, Koncz I, Patocskai B, Nesterenko VV, Antzelevitch C. Cellular mechanism underlying hypothermia-induced ventricular tachycardia/ventricular fibrillation in the setting of early repolarization and the protective effect of quinidine, cilostazol, and milrinone. Circ Arrhythm Electrophysiol. 2014 Feb; 7(1):134-42. PMID: 24429494.
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    96. Burashnikov A, Di Diego JM, Sicouri S, Doss MX, Sachinidis A, Barajas-Mart?nez H, Hu D, Minoura Y, Sydney Moise N, Kornreich BG, Chi L, Belardinelli L, Antzelevitch C. A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure. Eur J Heart Fail. 2014 Mar; 16(3):271-80. PMID: 24464846.
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    97. Hu D, Barajas-Mart?nez H, Terzic A, Park S, Pfeiffer R, Burashnikov E, Wu Y, Borggrefe M, Veltmann C, Schimpf R, Cai JJ, Nam GB, Deshmukh P, Scheinman M, Preminger M, Steinberg J, L?pez-Izquierdo A, Ponce-Balbuena D, Wolpert C, Ha?ssaguerre M, S?nchez-Chapula JA, Antzelevitch C. ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene. Int J Cardiol. 2014 Feb 15; 171(3):431-42. PMID: 24439875.
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    98. Antzelevitch C, Nesterenko V, Shryock JC, Rajamani S, Song Y, Belardinelli L. The role of late I Na in development of cardiac arrhythmias. Handb Exp Pharmacol. 2014; 221:137-68. PMID: 24737235.
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    99. Koncz I, Gurabi Z, Patocskai B, Panama BK, Sz?l T, Hu D, Barajas-Mart?nez H, Antzelevitch C. Mechanisms underlying the development of the electrocardiographic and arrhythmic manifestations of early repolarization syndrome. J Mol Cell Cardiol. 2014 Mar; 68:20-8. PMID: 24378566.
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    100. Barajas-Mart?nez H, Hu D, Antzelevitch C. [Genetic and molecular basis for sodium channel-mediated Brugada syndrome]. Arch Cardiol Mex. 2013 Oct-Dec; 83(4):295-302. PMID: 24269159.
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    101. Barajas-Mart?nez H, Hu D, Goodrow RJ, Joyce F, Antzelevitch C. Electrophysiologic characteristics and pharmacologic response of human cardiomyocytes isolated from a patient with hypertrophic cardiomyopathy. Pacing Clin Electrophysiol. 2013 Dec; 36(12):1512-5. PMID: 24117780.
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    102. Cordeiro JM, Panama BK, Goodrow R, Zygmunt AC, White C, Treat JA, Zeina T, Nesterenko VV, Di Diego JM, Burashnikov A, Antzelevitch C. Developmental changes in expression and biophysics of ion channels in the canine ventricle. J Mol Cell Cardiol. 2013 Nov; 64:79-89. PMID: 24035801.
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    103. Antzelevitch C. J wave syndromes: molecular and cellular mechanisms. J Electrocardiol. 2013 Nov-Dec; 46(6):510-8. PMID: 24011992.
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    104. Sz?l T, Koncz I, Antzelevitch C. Cellular mechanisms underlying the effects of milrinone and cilostazol to suppress arrhythmogenesis associated with Brugada syndrome. Heart Rhythm. 2013 Nov; 10(11):1720-7. PMID: 23911896.
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    105. Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, K??b S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, B?zieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R. Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet. 2013 Sep; 45(9):1044-9. PMID: 23872634.
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    106. Adler A, Topaz G, Heller K, Zeltser D, Ohayon T, Rozovski U, Halkin A, Rosso R, Ben-Shachar S, Antzelevitch C, Viskin S. Fever-induced Brugada pattern: how common is it and what does it mean? Heart Rhythm. 2013 Sep; 10(9):1375-82. PMID: 23872691.
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    107. Shryock JC, Song Y, Rajamani S, Antzelevitch C, Belardinelli L. The arrhythmogenic consequences of increasing late INa in the cardiomyocyte. Cardiovasc Res. 2013 Sep 01; 99(4):600-11. PMID: 23752976.
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    108. Liu Y, Bai R, Wang L, Zhang C, Zhao R, Wan D, Chen X, Caceres G, Barr D, Barajas-Martinez H, Antzelevitch C, Hu D. Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure. PLoS One. 2013; 8(5):e64603. PMID: 23741347.
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    109. Calloe K, Goodrow R, Olesen SP, Antzelevitch C, Cordeiro JM. Tissue-specific effects of acetylcholine in the canine heart. Am J Physiol Heart Circ Physiol. 2013 Jul 01; 305(1):H66-75. PMID: 23645460.
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    110. Raba AE, Cordeiro JM, Antzelevitch C, Beaumont J. Extending the conditions of application of an inversion of the Hodgkin-Huxley gating model. Bull Math Biol. 2013 May; 75(5):752-73. PMID: 23595789.
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    111. Cordeiro JM, Nesterenko VV, Sicouri S, Goodrow RJ, Treat JA, Desai M, Wu Y, Doss MX, Antzelevitch C, Di Diego JM. Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2013 Jul; 60:36-46. PMID: 23542310.
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    112. Sicouri S, Belardinelli L, Antzelevitch C. Antiarrhythmic effects of the highly selective late sodium channel current blocker GS-458967. Heart Rhythm. 2013 Jul; 10(7):1036-43. PMID: 23524321.
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    113. Aizawa Y, Takatsuki S, Kimura T, Nishiyama N, Fukumoto K, Tanimoto Y, Tanimoto K, Miyoshi S, Suzuki M, Yokoyama Y, Chinushi M, Watanabe I, Ogawa S, Aizawa Y, Antzelevitch C, Fukuda K. Ventricular fibrillation associated with complete right bundle branch block. Heart Rhythm. 2013 Jul; 10(7):1028-35. PMID: 23499623.
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    114. Minoura Y, Panama BK, Nesterenko VV, Betzenhauser M, Barajas-Mart?nez H, Hu D, Di Diego JM, Antzelevitch C. Effect of Wenxin Keli and quinidine to suppress arrhythmogenesis in an experimental model of Brugada syndrome. Heart Rhythm. 2013 Jul; 10(7):1054-62. PMID: 23499631.
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    115. Gussak I, Antzelevitch C. Early repolarization syndrome: a decade of progress. J Electrocardiol. 2013 Mar-Apr; 46(2):110-3. PMID: 23498751.
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    116. Jesty SA, Jung SW, Cordeiro JM, Gunn TM, Di Diego JM, Hemsley S, Kornreich BG, Hooker G, Antzelevitch C, Mo?se NS. Cardiomyocyte calcium cycling in a naturally occurring German shepherd dog model of inherited ventricular arrhythmia and sudden cardiac death. J Vet Cardiol. 2013 Mar; 15(1):5-14. PMID: 23434243.
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    117. Burashnikov A, Antzelevitch C. Role of late sodium channel current block in the management of atrial fibrillation. Cardiovasc Drugs Ther. 2013 Feb; 27(1):79-89. PMID: 23108433.
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    118. Antzelevitch C, Gussak I. Author's response to letter to the editor from Perez and Froelicher. J Electrocardiol. 2013 Mar-Apr; 46(2):116; discussion 117. PMID: 23375132.
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    119. Di Diego JM, Sicouri S, Myles RC, Burton FL, Smith GL, Antzelevitch C. Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations. J Mol Cell Cardiol. 2013 Jan; 54:53-64. PMID: 23142540.
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    120. Nathan AT, Antzelevitch C, Montenegro LM, Vetter VL. Case scenario: anesthesia-related cardiac arrest in a child with Timothy syndrome. Anesthesiology. 2012 Nov; 117(5):1117-26. PMID: 23011317.
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    121. Tomita M, Kitazawa H, Sato M, Okabe M, Antzelevitch C, Aizawa Y. A complete right bundle-branch block masking Brugada syndrome. J Electrocardiol. 2012 Nov-Dec; 45(6):780-2. PMID: 22832153.
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    122. Doss MX, Di Diego JM, Goodrow RJ, Wu Y, Cordeiro JM, Nesterenko VV, Barajas-Mart?nez H, Hu D, Urrutia J, Desai M, Treat JA, Sachinidis A, Antzelevitch C. Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr). PLoS One. 2012; 7(7):e40288. PMID: 22815737.
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    123. Burashnikov A, Barajas-Martinez H, Hu D, Nof E, Blazek J, Antzelevitch C. Atrial-selective prolongation of refractory period with AVE0118 is due principally to inhibition of sodium channel activity. J Cardiovasc Pharmacol. 2012 Jun; 59(6):539-46. PMID: 22370957.
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    124. Antzelevitch C. Genetic, molecular and cellular mechanisms underlying the J wave syndromes. Circ J. 2012; 76(5):1054-65. PMID: 22498570.
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    125. Giudicessi JR, Ye D, Kritzberger CJ, Nesterenko VV, Tester DJ, Antzelevitch C, Ackerman MJ. Novel mutations in the KCND3-encoded Kv4.3 K+ channel associated with autopsy-negative sudden unexplained death. Hum Mutat. 2012 Jun; 33(6):989-97. PMID: 22457051.
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    126. Cordeiro JM, Calloe K, Moise NS, Kornreich B, Giannandrea D, Di Diego JM, Olesen SP, Antzelevitch C. Physiological consequences of transient outward K+ current activation during heart failure in the canine left ventricle. J Mol Cell Cardiol. 2012 Jun; 52(6):1291-8. PMID: 22434032.
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    127. Sicouri S, Blazek J, Belardinelli L, Antzelevitch C. Electrophysiological characteristics of canine superior vena cava sleeve preparations: effect of ranolazine. Circ Arrhythm Electrophysiol. 2012 Apr; 5(2):371-9. PMID: 22407414.
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    128. Conesa C, Doss MX, Antzelevitch C, Sachinidis A, Sancho J, Carrodeguas JA. Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening. Stem Cell Rev Rep. 2012 Mar; 8(1):116-27. PMID: 21617963.
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    129. Crotti L, Hu D, Barajas-Martinez H, De Ferrari GM, Oliva A, Insolia R, Pollevick GD, Dagradi F, Guerchicoff A, Greco F, Schwartz PJ, Viskin S, Antzelevitch C. Torsades de pointes following acute myocardial infarction: evidence for a deadly link with a common genetic variant. Heart Rhythm. 2012 Jul; 9(7):1104-12. PMID: 22338672.
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    130. Burashnikov A, Pourrier M, Gibson JK, Lynch JJ, Antzelevitch C. Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol. Circ Arrhythm Electrophysiol. 2012 Apr; 5(2):400-8. PMID: 22322366.
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    131. Adler A, van der Werf C, Postema PG, Rosso R, Bhuiyan ZA, Kalman JM, Vohra JK, Guevara-Valdivia ME, Marquez MF, Halkin A, Benhorin J, Antzelevitch C, Wilde AA, Viskin S. The phenomenon of "QT stunning": the abnormal QT prolongation provoked by standing persists even as the heart rate returns to normal in patients with long QT syndrome. Heart Rhythm. 2012 Jun; 9(6):901-8. PMID: 22300664.
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    132. Schimpf R, Veltmann C, Papavassiliu T, Rudic B, G?ksu T, Kuschyk J, Wolpert C, Antzelevitch C, Ebner A, Borggrefe M, Brandt C. Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide. Heart Rhythm. 2012 May; 9(5):776-81. PMID: 22245794.
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    133. Hu D, Barajas-Mart?nez H, Medeiros-Domingo A, Crotti L, Veltmann C, Schimpf R, Urrutia J, Alday A, Casis O, Pfeiffer R, Burashnikov E, Caceres G, Tester DJ, Wolpert C, Borggrefe M, Schwartz P, Ackerman MJ, Antzelevitch C. A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents. Heart Rhythm. 2012 May; 9(5):760-9. PMID: 22155597.
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    134. Gillis J, Burashnikov E, Antzelevitch C, Blaser S, Gross G, Turner L, Babul-Hirji R, Chitayat D. Long QT, syndactyly, joint contractures, stroke and novel CACNA1C mutation: expanding the spectrum of Timothy syndrome. Am J Med Genet A. 2012 Jan; 158A(1):182-7. PMID: 22106044.
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    135. Kanter RJ, Pfeiffer R, Hu D, Barajas-Martinez H, Carboni MP, Antzelevitch C. Brugada-like syndrome in infancy presenting with rapid ventricular tachycardia and intraventricular conduction delay. Circulation. 2012 Jan 03; 125(1):14-22. PMID: 22090166.
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    136. Barajas-Mart?nez H, Hu D, Ferrer T, Onetti CG, Wu Y, Burashnikov E, Boyle M, Surman T, Urrutia J, Veltmann C, Schimpf R, Borggrefe M, Wolpert C, Ibrahim BB, S?nchez-Chapula JA, Winters S, Ha?ssaguerre M, Antzelevitch C. Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8. Heart Rhythm. 2012 Apr; 9(4):548-55. PMID: 22056721.
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    137. Burashnikov A, Antzelevitch C. Ranolazine versus amiodarone for prevention of postoperative atrial fibrillation. Future Cardiol. 2011 Nov; 7(6):733-7. PMID: 22050058.
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    138. Minoura Y, Di Diego JM, Barajas-Mart?nez H, Zygmunt AC, Hu D, Sicouri S, Antzelevitch C. Ionic and cellular mechanisms underlying the development of acquired Brugada syndrome in patients treated with antidepressants. J Cardiovasc Electrophysiol. 2012 Apr; 23(4):423-32. PMID: 22034916.
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    139. Sicouri S, Pourrier M, Gibson JK, Lynch JJ, Antzelevitch C. Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations. Heart Rhythm. 2012 Mar; 9(3):422-9. PMID: 22019863.
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    140. Burashnikov A, Belardinelli L, Antzelevitch C. Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone. J Pharmacol Exp Ther. 2012 Jan; 340(1):161-8. PMID: 22005044.
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    141. Antzelevitch C, Yan GX. J-wave syndromes. from cell to bedside. J Electrocardiol. 2011 Nov-Dec; 44(6):656-61. PMID: 21908004.
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    142. Calloe K, Schmitt N, Grubb S, Pfeiffer R, David JP, Kanter R, Cordeiro JM, Antzelevitch C. Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A. Can J Physiol Pharmacol. 2011 Oct; 89(10):723-36. PMID: 21895525.
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    143. Burashnikov A, Petroski A, Hu D, Barajas-Martinez H, Antzelevitch C. Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation. Heart Rhythm. 2012 Jan; 9(1):125-31. PMID: 21884675.
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    144. Burashnikov A, Antzelevitch C. Novel pharmacological targets for the rhythm control management of atrial fibrillation. Pharmacol Ther. 2011 Dec; 132(3):300-13. PMID: 21867730.
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    145. Nesterenko VV, Zygmunt AC, Rajamani S, Belardinelli L, Antzelevitch C. Mechanisms of atrial-selective block of Na? channels by ranolazine: II. Insights from a mathematical model. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1615-24. PMID: 21821780.
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    146. Zygmunt AC, Nesterenko VV, Rajamani S, Hu D, Barajas-Martinez H, Belardinelli L, Antzelevitch C. Mechanisms of atrial-selective block of Na? channels by ranolazine: I. Experimental analysis of the use-dependent block. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1606-14. PMID: 21821778.
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    147. Nattel S, Antzelevitch C, Noble D. Resolving the M-cell debate: why and how. Heart Rhythm. 2011 Aug; 8(8):1293-5. PMID: 21787998.
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    148. Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, Fink M, Fischmeister R, Franz MR, Garny A, Giles WR, Hannes T, Harding SE, Hunter PJ, Iribe G, Jalife J, Johnson CR, Kass RS, Kodama I, Koren G, Lord P, Markhasin VS, Matsuoka S, McCulloch AD, Mirams GR, Morley GE, Nattel S, Noble D, Olesen SP, Panfilov AV, Trayanova NA, Ravens U, Richard S, Rosenbaum DS, Rudy Y, Sachs F, Sachse FB, Saint DA, Schotten U, Solovyova O, Taggart P, Tung L, Varr? A, Volders PG, Wang K, Weiss JN, Wettwer E, White E, Wilders R, Winslow RL, Kohl P. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Prog Biophys Mol Biol. 2011 Oct; 107(1):4-10. PMID: 21745496.
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    149. Di Diego JM, Antzelevitch C. Ischemic ventricular arrhythmias: experimental models and their clinical relevance. Heart Rhythm. 2011 Dec; 8(12):1963-8. PMID: 21740880.
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    150. Gaw AC, Lee B, Gervacio-Domingo G, Antzelevitch C, Divinagracia R, Jocano F. Unraveling the Enigma of Bangungut: Is Sudden Unexplained Nocturnal Death Syndrome (SUNDS) in the Philippines a Disease Allelic to the Brugada Syndrome? Philipp J Intern Med. 2011 Jul; 49(3):165-176. PMID: 22844180.
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    151. Nof E, Barajas-Martinez H, Eldar M, Urrutia J, Caceres G, Rosenfeld G, Bar-Lev D, Feinberg M, Burashnikov E, Casis O, Hu D, Glikson M, Antzelevitch C. LQT5 masquerading as LQT2: a dominant negative effect of KCNE1-D85N rare polymorphism on KCNH2 current. Europace. 2011 Oct; 13(10):1478-83. PMID: 21712262.
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    152. Estes NA, Sacco RL, Al-Khatib SM, Ellinor PT, Bezanson J, Alonso A, Antzelevitch C, Brockman RG, Chen PS, Chugh SS, Curtis AB, DiMarco JP, Ellenbogen KA, Epstein AE, Ezekowitz MD, Fayad P, Gage BF, Go AS, Hlatky MA, Hylek EM, Jerosch-Herold M, Konstam MA, Lee R, Packer DL, Po SS, Prystowsky EN, Redline S, Rosenberg Y, Van Wagoner DR, Wood KA, Yue L, Benjamin EJ. American Heart Association atrial fibrillation research summit: a conference report from the American Heart Association. Circulation. 2011 Jul 19; 124(3):363-72. PMID: 21709057.
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    153. Murphy L, Renodin D, Antzelevitch C, Di Diego JM, Cordeiro JM. Extracellular proton depression of peak and late Na? current in the canine left ventricle. Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3):H936-44. PMID: 21685271.
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    154. Nof E, Belhassen B, Arad M, Bhuiyan ZA, Antzelevitch C, Rosso R, Fogelman R, Luria D, El-Ani D, Mannens MM, Viskin S, Eldar M, Wilde AA, Glikson M. Postpacing abnormal repolarization in catecholaminergic polymorphic ventricular tachycardia associated with a mutation in the cardiac ryanodine receptor gene. Heart Rhythm. 2011 Oct; 8(10):1546-52. PMID: 21699856.
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    155. Antzelevitch C, Yan GX, Viskin S. Rationale for the use of the terms J-wave syndromes and early repolarization. J Am Coll Cardiol. 2011 Apr 12; 57(15):1587-90. PMID: 21474038.
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    156. Calloe K, Nof E, Jespersen T, Di Diego JM, Chlus N, Olesen SP, Antzelevitch C, Cordeiro JM. Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes. J Cardiovasc Electrophysiol. 2011 Sep; 22(9):1057-66. PMID: 21457383.
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    157. Antzelevitch C, Burashnikov A, Sicouri S, Belardinelli L. Electrophysiologic basis for the antiarrhythmic actions of ranolazine. Heart Rhythm. 2011 Aug; 8(8):1281-90. PMID: 21421082.
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    158. Templin C, Ghadri JR, Rougier JS, Baumer A, Kaplan V, Albesa M, Sticht H, Rauch A, Puleo C, Hu D, Barajas-Martinez H, Antzelevitch C, L?scher TF, Abriel H, Duru F. Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). Eur Heart J. 2011 May; 32(9):1077-88. PMID: 21383000.
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    159. Napolitano C, Antzelevitch C. Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channel. Circ Res. 2011 Mar 04; 108(5):607-18. PMID: 21372292.
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    160. Antzelevitch C, Burashnikov A. Overview of Basic Mechanisms of Cardiac Arrhythmia. Card Electrophysiol Clin. 2011 Mar 01; 3(1):23-45. PMID: 21892379.
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    161. Wang D, Yan GX, Antzelevitch C. The J Wave Syndromes and their Role in Sudden Cardiac Death. Card Electrophysiol Clin. 2011 Mar 01; 3(1):47-56. PMID: 21499517.
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    162. Burashnikov A, Antzelevitch C. Advances in the Pharmacologic Management of Atrial Fibrillation. Card Electrophysiol Clin. 2011 Mar; 3(1):157-167. PMID: 21731596.
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    163. Giudicessi JR, Ye D, Tester DJ, Crotti L, Mugione A, Nesterenko VV, Albertson RM, Antzelevitch C, Schwartz PJ, Ackerman MJ. Transient outward current (I(to)) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome. Heart Rhythm. 2011 Jul; 8(7):1024-32. PMID: 21349352.
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    164. Sicouri S, Gianetti B, Zygmunt AC, Cordeiro JM, Antzelevitch C. Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations. J Am Coll Cardiol. 2011 Feb 22; 57(8):986-93. PMID: 21329846.
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    165. Sicouri S, Cordeiro JM, Talarico M, Antzelevitch C. Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations. J Cardiovasc Electrophysiol. 2011 Jun; 22(6):698-705. PMID: 21159010.
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    166. Barajas-Martinez H, Hu D, Ontiveros G, Caceres G, Desai M, Burashnikov E, Scaglione J, Antzelevitch C. Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry. Circ Cardiovasc Genet. 2011 Feb; 4(1):51-7. PMID: 21148745.
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    167. Cordeiro JM, Perez GJ, Schmitt N, Pfeiffer R, Nesterenko VV, Burashnikov E, Veltmann C, Borggrefe M, Wolpert C, Schimpf R, Antzelevitch C. Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2. Can J Physiol Pharmacol. 2010 Dec; 88(12):1181-90. PMID: 21164565.
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    168. Laish-Farkash A, Glikson M, Brass D, Marek-Yagel D, Pras E, Dascal N, Antzelevitch C, Nof E, Reznik H, Eldar M, Luria D. A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews. J Cardiovasc Electrophysiol. 2010 Dec; 21(12):1365-72. PMID: 20662977.
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    169. Burashnikov E, Pfeiffer R, Barajas-Martinez H, Delp?n E, Hu D, Desai M, Borggrefe M, H?issaguerre M, Kanter R, Pollevick GD, Guerchicoff A, Lai?o R, Marieb M, Nademanee K, Nam GB, Robles R, Schimpf R, Stapleton DD, Viskin S, Winters S, Wolpert C, Zimmern S, Veltmann C, Antzelevitch C. Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death. Heart Rhythm. 2010 Dec; 7(12):1872-82. PMID: 20817017.
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    170. Burashnikov A, Sicouri S, Di Diego JM, Belardinelli L, Antzelevitch C. Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation. J Am Coll Cardiol. 2010 Oct 05; 56(15):1216-24. PMID: 20883928.
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    171. Sicouri S, Antzelevitch C. Pulmonary Vein Sleeves as a Pharmacologic Model for the Study of Atrial Fibrillation. Electrofisiol Arritm. 2010 Oct; 3(4):108-113. PMID: 24999375.
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    172. Antzelevitch C, Barajas-Martinez H. A gain-of-function I(K-ATP) mutation and its role in sudden cardiac death associated with J-wave syndromes. Heart Rhythm. 2010 Oct; 7(10):1472-4. PMID: 20736095.
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    173. Patel C, Yan GX, Antzelevitch C. Short QT syndrome: from bench to bedside. Circ Arrhythm Electrophysiol. 2010 Aug; 3(4):401-8. PMID: 20716721.
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    174. Wilde AA, Postema PG, Di Diego JM, Viskin S, Morita H, Fish JM, Antzelevitch C. The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization. J Mol Cell Cardiol. 2010 Oct; 49(4):543-53. PMID: 20659475.
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    175. Burashnikov A, Zygmunt AC, Di Diego JM, Linhardt G, Carlsson L, Antzelevitch C. AZD1305 exerts atrial predominant electrophysiological actions and is effective in suppressing atrial fibrillation and preventing its reinduction in the dog. J Cardiovasc Pharmacol. 2010 Jul; 56(1):80-90. PMID: 20386458.
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    176. Burashnikov A, Belardinelli L, Antzelevitch C. Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria. Heart Rhythm. 2010 Sep; 7(9):1273-9. PMID: 20478403.
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    177. Bloch Thomsen PE, Johannessen A, Jons C, Hansen TF, Kanters JK, Haarbo J, Hansen J, Christiansen LK, Sogaard P, Saermark K, Antzelevitch C. The role of local voltage potentials in outflow tract ectopy. Europace. 2010 Jun; 12(6):850-60. PMID: 20413613.
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    178. Sicouri S, Carlsson L, Antzelevitch C. Electrophysiologic and antiarrhythmic effects of AZD1305 in canine pulmonary vein sleeves. J Pharmacol Exp Ther. 2010 Jul; 334(1):255-9. PMID: 20360353.
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    179. Antzelevitch C. M cells in the human heart. Circ Res. 2010 Mar 19; 106(5):815-7. PMID: 20299671.
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    180. Burashnikov A, Antzelevitch C. New developments in atrial antiarrhythmic drug therapy. Nat Rev Cardiol. 2010 Mar; 7(3):139-48. PMID: 20179721.
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    181. Nof E, Cordeiro JM, P?rez GJ, Scornik FS, Calloe K, Love B, Burashnikov E, Caceres G, Gunsburg M, Antzelevitch C. A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death. Circ Cardiovasc Genet. 2010 Apr; 3(2):199-206. PMID: 20181576.
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    182. Antzelevitch C, Burashnikov A. Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation. Ann N Y Acad Sci. 2010 Feb; 1188:78-86. PMID: 20201889.
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    183. Viskin S, Postema PG, Bhuiyan ZA, Rosso R, Kalman JM, Vohra JK, Guevara-Valdivia ME, Marquez MF, Kogan E, Belhassen B, Glikson M, Strasberg B, Antzelevitch C, Wilde AA. The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome. J Am Coll Cardiol. 2010 May 04; 55(18):1955-61. PMID: 20116193.
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    184. Gunaseeli I, Doss MX, Antzelevitch C, Hescheler J, Sachinidis A. Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery. Curr Med Chem. 2010; 17(8):759-66. PMID: 20088756.
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    185. Burashnikov A, Antzelevitch C. Advances in the Pharmacological Treatment of Atrial Fibrillation. Curr Med Lit Cardiol. 2010 Jan 01; 29(1):1-5. PMID: 21152111.
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    186. Chamberland C, Barajas-Martinez H, Haufe V, Fecteau MH, Delabre JF, Burashnikov A, Antzelevitch C, Lesur O, Chraibi A, Sarret P, Dumaine R. Modulation of canine cardiac sodium current by Apelin. J Mol Cell Cardiol. 2010 Apr; 48(4):694-701. PMID: 20036246.
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    187. Hu D, Barajas-Martinez H, Nesterenko VV, Pfeiffer R, Guerchicoff A, Cordeiro JM, Curtis AB, Pollevick GD, Wu Y, Burashnikov E, Antzelevitch C. Dual variation in SCN5A and CACNB2b underlies the development of cardiac conduction disease without Brugada syndrome. Pacing Clin Electrophysiol. 2010 Mar; 33(3):274-85. PMID: 20025708.
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    188. Antzelevitch C, Yan GX. J wave syndromes. Heart Rhythm. 2010 Apr; 7(4):549-58. PMID: 20153265.
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    189. Sicouri S, Burashnikov A, Belardinelli L, Antzelevitch C. Synergistic electrophysiologic and antiarrhythmic effects of the combination of ranolazine and chronic amiodarone in canine atria. Circ Arrhythm Electrophysiol. 2010 Feb; 3(1):88-95. PMID: 19952329.
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    190. Sicouri S, Glass A, Ferreiro M, Antzelevitch C. Transseptal dispersion of repolarization and its role in the development of Torsade de Pointes arrhythmias. J Cardiovasc Electrophysiol. 2010 Apr; 21(4):441-7. PMID: 19909385.
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    191. Nam GB, Ko KH, Kim J, Park KM, Rhee KS, Choi KJ, Kim YH, Antzelevitch C. Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs. Brugada syndrome. Eur Heart J. 2010 Feb; 31(3):330-9. PMID: 19880418.
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    192. Nof E, Burashnikov A, Antzelevitch C. Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy. Heart Rhythm. 2010; 7(2):251-7. PMID: 20042373.
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    193. Wu J, Shimizu W, Ding WG, Ohno S, Toyoda F, Itoh H, Zang WJ, Miyamoto Y, Kamakura S, Matsuura H, Nademanee K, Brugada J, Brugada P, Brugada R, Vatta M, Towbin JA, Antzelevitch C, Horie M. KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders. Heart Rhythm. 2010; 7(2):199-205. PMID: 20042375.
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    194. Kapplinger JD, Tester DJ, Alders M, Benito B, Berthet M, Brugada J, Brugada P, Fressart V, Guerchicoff A, Harris-Kerr C, Kamakura S, Kyndt F, Koopmann TT, Miyamoto Y, Pfeiffer R, Pollevick GD, Probst V, Zumhagen S, Vatta M, Towbin JA, Shimizu W, Schulze-Bahr E, Antzelevitch C, Salisbury BA, Guicheney P, Wilde AA, Brugada R, Schott JJ, Ackerman MJ. An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. Heart Rhythm. 2010 Jan; 7(1):33-46. PMID: 20129283.
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    195. Nof E, Antzelevitch C, Glikson M. The Contribution of HCN4 to normal sinus node function in humans and animal models. Pacing Clin Electrophysiol. 2010 Jan; 33(1):100-6. PMID: 19796353.
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    196. Antzelevitch C, Burashnikov A. Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation. J Electrocardiol. 2009 Nov-Dec; 42(6):543-8. PMID: 19698954.
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    197. Calloe K, Soltysinska E, Jespersen T, Lundby A, Antzelevitch C, Olesen SP, Cordeiro JM. Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle. J Mol Cell Cardiol. 2010 Jan; 48(1):191-200. PMID: 19632239.
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    198. Viskin S, Rosso R, M?rquez MF, Antzelevitch C. The acquired Brugada syndrome and the paradox of choice. Heart Rhythm. 2009 Sep; 6(9):1342-4. PMID: 19716090.
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    199. Burashnikov A, Antzelevitch C. New pharmacological strategies for the treatment of atrial fibrillation. Ann Noninvasive Electrocardiol. 2009 Jul; 14(3):290-300. PMID: 19614642.
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    200. Burashnikov A, Antzelevitch C. Atrial-selective sodium channel block for the treatment of atrial fibrillation. Expert Opin Emerg Drugs. 2009 Jun; 14(2):233-49. PMID: 19466903.
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    201. Cordeiro JM, Marieb M, Pfeiffer R, Calloe K, Burashnikov E, Antzelevitch C. Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome. J Mol Cell Cardiol. 2009 May; 46(5):695-703. PMID: 19358333.
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    202. Hu D, Barajas-Martinez H, Burashnikov E, Springer M, Wu Y, Varro A, Pfeiffer R, Koopmann TT, Cordeiro JM, Guerchicoff A, Pollevick GD, Antzelevitch C. A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype. Circ Cardiovasc Genet. 2009 Jun; 2(3):270-8. PMID: 20031595.
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    203. Nof E, Glikson M, Antzelevitch C. Genetics and Sinus Node Dysfunction. J Atr Fibrillation. 2009 Apr-May; 1(6):151. PMID: 28496616.
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    204. Sicouri S, Belardinelli L, Carlsson L, Antzelevitch C. Potent antiarrhythmic effects of chronic amiodarone in canine pulmonary vein sleeve preparations. J Cardiovasc Electrophysiol. 2009 Jul; 20(7):803-10. PMID: 19298559.
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    205. Patel C, Burke JF, Patel H, Gupta P, Kowey PR, Antzelevitch C, Yan GX. Is there a significant transmural gradient in repolarization time in the intact heart? Cellular basis of the T wave: a century of controversy. Circ Arrhythm Electrophysiol. 2009 Feb; 2(1):80-8. PMID: 19808446.
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    206. Calloe K, Cordeiro JM, Di Diego JM, Hansen RS, Grunnet M, Olesen SP, Antzelevitch C. A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome. Cardiovasc Res. 2009 Mar 01; 81(4):686-94. PMID: 19073629.
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    207. Viskin S, Wilde AA, Tan HL, Antzelevitch C, Shimizu W, Belhassen B. Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry. Heart Rhythm. 2009 Mar; 6(3):401-4. PMID: 19251219.
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    208. P?rez Riera AR, Filho CF, Uchida AH, Zhang L, Antzelevitch C, Schapachnik E, Dubner S, Ferreira C. Study of the extent of the information of cardiologists from S?o Paulo city, Brazil, regarding a low-prevalence entity: Brugada syndrome. Ann Noninvasive Electrocardiol. 2008 Oct; 13(4):352-63. PMID: 18973492.
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    209. Burashnikov A, Di Diego JM, Sicouri S, Ferreiro M, Carlsson L, Antzelevitch C. Atrial-selective effects of chronic amiodarone in the management of atrial fibrillation. Heart Rhythm. 2008 Dec; 5(12):1735-42. PMID: 19084813.
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    210. Wu L, Guo D, Li H, Hackett J, Yan GX, Jiao Z, Antzelevitch C, Shryock JC, Belardinelli L. Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine. Heart Rhythm. 2008 Dec; 5(12):1726-34. PMID: 19084812.
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    211. Antzelevitch C, Nof E. Brugada syndrome: recent advances and controversies. Curr Cardiol Rep. 2008 Sep; 10(5):376-83. PMID: 18715534.
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    212. Burashnikov A, Antzelevitch C. Can inhibition of IKur promote atrial fibrillation? Heart Rhythm. 2008 Sep; 5(9):1304-9. PMID: 18774108.
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    213. Delp?n E, Cordeiro JM, N??ez L, Thomsen PE, Guerchicoff A, Pollevick GD, Wu Y, Kanters JK, Larsen CT, Hofman-Bang J, Burashnikov E, Christiansen M, Antzelevitch C. Functional effects of KCNE3 mutation and its role in the development of Brugada syndrome. Circ Arrhythm Electrophysiol. 2008 Aug; 1(3):209-18. PMID: 19122847.
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    214. Burashnikov A, Antzelevitch C. Atrial-selective sodium channel blockers: do they exist? J Cardiovasc Pharmacol. 2008 Aug; 52(2):121-8. PMID: 18670368.
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    215. Burashnikov A, Shimizu W, Antzelevitch C. Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-QT Conditions. Circ Arrhythm Electrophysiol. 2008 Aug; 1(3):202-8. PMID: 19649147.
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    216. Wolpert C, Veltmann C, Schimpf R, Antzelevitch C, Gussak I, Borggrefe M. Is a narrow and tall QRS complex an ECG marker for sudden death? Heart Rhythm. 2008 Sep; 5(9):1339-45. PMID: 18774114.
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    217. Barajas-Mart?nez HM, Hu D, Cordeiro JM, Wu Y, Kovacs RJ, Meltser H, Kui H, Elena B, Brugada R, Antzelevitch C, Dumaine R. Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel. Circ Res. 2008 Aug 15; 103(4):396-404. PMID: 18599870.
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    218. Nof E, Antzelevitch C. Risk stratification [corrected] of Brugada syndrome revisited. Isr Med Assoc J. 2008 Jun; 10(6):462-4. PMID: 18669148.
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    219. Nam GB, Kim YH, Antzelevitch C. Augmentation of J waves and electrical storms in patients with early repolarization. N Engl J Med. 2008 May 08; 358(19):2078-9. PMID: 18463391.
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    220. Cordeiro JM, Mazza M, Goodrow R, Ulahannan N, Antzelevitch C, Di Diego JM. Functionally distinct sodium channels in ventricular epicardial and endocardial cells contribute to a greater sensitivity of the epicardium to electrical depression. Am J Physiol Heart Circ Physiol. 2008 Jul; 295(1):H154-62. PMID: 18456729.
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    221. Patel C, Antzelevitch C. Pharmacological approach to the treatment of long and short QT syndromes. Pharmacol Ther. 2008 Apr; 118(1):138-51. PMID: 18378319.
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    222. Francis J, Antzelevitch C. Atrial fibrillation and Brugada syndrome. J Am Coll Cardiol. 2008 Mar 25; 51(12):1149-53. PMID: 18355651.
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    223. Sicouri S, Glass A, Belardinelli L, Antzelevitch C. Antiarrhythmic effects of ranolazine in canine pulmonary vein sleeve preparations. Heart Rhythm. 2008 Jul; 5(7):1019-26. PMID: 18598958.
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    224. Antzelevitch C. Ranolazine: a new antiarrhythmic agent for patients with non-ST-segment elevation acute coronary syndromes? Nat Clin Pract Cardiovasc Med. 2008 May; 5(5):248-9. PMID: 18332892.
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    225. Sicouri S, Antzelevitch C. Sudden cardiac death secondary to antidepressant and antipsychotic drugs. Expert Opin Drug Saf. 2008 Mar; 7(2):181-94. PMID: 18324881.
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    226. Burashnikov A, Di Diego JM, Zygmunt AC, Belardinelli L, Antzelevitch C. Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation. Ann N Y Acad Sci. 2008 Mar; 1123:105-12. PMID: 18375582.
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    227. Ravn LS, Aizawa Y, Pollevick GD, Hofman-Bang J, Cordeiro JM, Dixen U, Jensen G, Wu Y, Burashnikov E, Haunso S, Guerchicoff A, Hu D, Svendsen JH, Christiansen M, Antzelevitch C. Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation. Heart Rhythm. 2008 Mar; 5(3):427-35. PMID: 18313602.
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    228. Patel C, Antzelevitch C. Cellular basis for arrhythmogenesis in an experimental model of the SQT1 form of the short QT syndrome. Heart Rhythm. 2008 Apr; 5(4):585-90. PMID: 18362027.
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    229. Antzelevitch C. Drug-induced spatial dispersion of repolarization. Cardiol J. 2008; 15(2):100-21. PMID: 18651395.
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    230. Burashnikov A, Antzelevitch C. How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation? J Atr Fibrillation. 2008; 1(2):98-107. PMID: 21057583.
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    231. Fish JM, Antzelevitch C. Cellular mechanism and arrhythmogenic potential of T-wave alternans in the Brugada syndrome. J Cardiovasc Electrophysiol. 2008 Mar; 19(3):301-8. PMID: 18031511.
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    232. Wu L, Rajamani S, Shryock JC, Li H, Ruskin J, Antzelevitch C, Belardinelli L. Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone. Cardiovasc Res. 2008 Feb 01; 77(3):481-8. PMID: 18006430.
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    233. Glass A, Sicouri S, Antzelevitch C. Development of a coronary-perfused interventricular septal preparation as a model for studying the role of the septum in arrhythmogenesis. J Electrocardiol. 2007 Nov-Dec; 40(6 Suppl):S142-4. PMID: 17993311.
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    234. Hu D, Viskin S, Oliva A, Cordeiro JM, Guerchicoff A, Pollevick GD, Antzelevitch C. Genetic predisposition and cellular basis for ischemia-induced ST-segment changes and arrhythmias. J Electrocardiol. 2007 Nov-Dec; 40(6 Suppl):S26-9. PMID: 17993325.
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    235. Schimpf R, Antzelevitch C, Haghi D, Giustetto C, Pizzuti A, Gaita F, Veltmann C, Wolpert C, Borggrefe M. Electromechanical coupling in patients with the short QT syndrome: further insights into the mechanoelectrical hypothesis of the U wave. Heart Rhythm. 2008 Feb; 5(2):241-5. PMID: 18242547.
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    236. Cordeiro JM, Malone JE, Di Diego JM, Scornik FS, Aistrup GL, Antzelevitch C, Wasserstrom JA. Cellular and subcellular alternans in the canine left ventricle. Am J Physiol Heart Circ Physiol. 2007 Dec; 293(6):H3506-16. PMID: 17906109.
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    237. Burashnikov A, Di Diego JM, Zygmunt AC, Belardinelli L, Antzelevitch C. Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine. Circulation. 2007 Sep 25; 116(13):1449-57. PMID: 17785620.
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    238. Antzelevitch C. Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes. Europace. 2007 Sep; 9 Suppl 4:iv4-15. PMID: 17766323.
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    239. Viskin S, Antzelevitch C, M?rquez MF, Belhassen B. Quinidine: a valuable medication joins the list of 'endangered species'. Europace. 2007 Dec; 9(12):1105-6. PMID: 17761793.
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    240. Aizawa Y, Ueda K, Scornik F, Cordeiro JM, Wu Y, Desai M, Guerchicoff A, Nagata Y, Iesaka Y, Kimura A, Hiraoka M, Antzelevitch C. A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome. J Cardiovasc Electrophysiol. 2007 Sep; 18(9):972-7. PMID: 17655673.
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    241. Antzelevitch C. Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2024-38. PMID: 17586620.
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    242. Antzelevitch C, Sicouri S, Di Diego JM, Burashnikov A, Viskin S, Shimizu W, Yan GX, Kowey P, Zhang L. Does Tpeak-Tend provide an index of transmural dispersion of repolarization? Heart Rhythm. 2007 Aug; 4(8):1114-6; author reply 1116-9. PMID: 17675094.
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    243. Shinde R, Rituparna S, Shinde S, Suresh S, Makhale C, Chandrashekhar M, Grant P, Purvez G, Sathe S, Sunil S, Durairaj M, Durairaj M, Lokhandwala Y, Yash L, Di Diego J, DI Diego JM, Antzelevitch C, Charles A. Occurrence of "J waves" in 12-lead ECG as a marker of acute ischemia and their cellular basis. Pacing Clin Electrophysiol. 2007 Jun; 30(6):817-9. PMID: 17547622.
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    244. Hu D, Viskin S, Oliva A, Carrier T, Cordeiro JM, Barajas-Martinez H, Wu Y, Burashnikov E, Sicouri S, Brugada R, Rosso R, Guerchicoff A, Pollevick GD, Antzelevitch C. Novel mutation in the SCN5A gene associated with arrhythmic storm development during acute myocardial infarction. Heart Rhythm. 2007 Aug; 4(8):1072-80. PMID: 17675083.
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    245. Antzelevitch C. Heterogeneity and cardiac arrhythmias: an overview. Heart Rhythm. 2007 Jul; 4(7):964-72. PMID: 17599687.
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    246. Antzelevitch C. Genetic basis of Brugada syndrome. Heart Rhythm. 2007 Jun; 4(6):756-7. PMID: 17556198.
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    247. Antzelevitch C, Pollevick GD, Cordeiro JM, Casis O, Sanguinetti MC, Aizawa Y, Guerchicoff A, Pfeiffer R, Oliva A, Wollnik B, Gelber P, Bonaros EP, Burashnikov E, Wu Y, Sargent JD, Schickel S, Oberheiden R, Bhatia A, Hsu LF, Ha?ssaguerre M, Schimpf R, Borggrefe M, Wolpert C. Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death. Circulation. 2007 Jan 30; 115(4):442-9. PMID: 17224476.
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    248. Sicouri S, Timothy KW, Zygmunt AC, Glass A, Goodrow RJ, Belardinelli L, Antzelevitch C. Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine. Heart Rhythm. 2007 May; 4(5):638-47. PMID: 17467634.
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    249. Antzelevitch C, Wilde A, Eckardt L, Hiraoka M, Corrado D. Diagnostic and genetic aspects of the Brugada and other inherited arrhythmias syndromes. J Electrocardiol. 2007 Jan; 40(1 SUPPLIMENT):S11-S14. PMID: 18509512.
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    250. Cordeiro JM, Barajas-Martinez H, Hong K, Burashnikov E, Pfeiffer R, Orsino AM, Wu YS, Hu D, Brugada J, Brugada P, Antzelevitch C, Dumaine R, Brugada R. Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome. Circulation. 2006 Nov 07; 114(19):2026-33. PMID: 17075016.
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    251. Antzelevitch C. Cellular basis for the repolarization waves of the ECG. Ann N Y Acad Sci. 2006 Oct; 1080:268-81. PMID: 17132789.
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    252. Antzelevitch C. Brugada syndrome. Pacing Clin Electrophysiol. 2006 Oct; 29(10):1130-59. PMID: 17038146.
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    253. Dumaine R, Antzelevitch C. Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome? J Mol Cell Cardiol. 2006 Sep; 41(3):421-3. PMID: 16863649.
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    254. Vernooy K, Sicouri S, Dumaine R, Hong K, Oliva A, Burashnikov E, Timmermans C, Delhaas T, Crijns HJ, Antzelevitch C, Rodriguez LM, Brugada R. Genetic and biophysical basis for bupivacaine-induced ST segment elevation and VT/VF. Anesthesia unmasked Brugada syndrome. Heart Rhythm. 2006 Sep; 3(9):1074-8. PMID: 16945804.
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    255. Antzelevitch C, Belardinelli L. The role of sodium channel current in modulating transmural dispersion of repolarization and arrhythmogenesis. J Cardiovasc Electrophysiol. 2006 May; 17 Suppl 1:S79-S85. PMID: 16686686.
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    256. Liu T, Brown BS, Wu Y, Antzelevitch C, Kowey PR, Yan GX. Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias. Heart Rhythm. 2006 Aug; 3(8):948-56. PMID: 16876745.
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    257. Castro Hevia J, Antzelevitch C, Torn?s B?rzaga F, Dorantes S?nchez M, Dortic?s Balea F, Zayas Molina R, Qui?ones P?rez MA, Fayad Rodr?guez Y. Tpeak-Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricular fibrillation in patients with the Brugada syndrome. J Am Coll Cardiol. 2006 May 02; 47(9):1828-34. PMID: 16682308.
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    258. Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, Moss AJ, Seidman CE, Young JB. Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation. 2006 Apr 11; 113(14):1807-16. PMID: 16567565.
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    259. Scornik FS, Desai M, Brugada R, Guerchicoff A, Pollevick GD, Antzelevitch C, P?rez GJ. Functional expression of "cardiac-type" Nav1.5 sodium channel in canine intracardiac ganglia. Heart Rhythm. 2006 Jul; 3(7):842-50. PMID: 16818219.
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    260. Fish JM, Welchons DR, Kim YS, Lee SH, Ho WK, Antzelevitch C. Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome. Circulation. 2006 Mar 21; 113(11):1393-400. PMID: 16534004.
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    261. Tsuboi M, Antzelevitch C. Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7). Heart Rhythm. 2006 Mar; 3(3):328-35. PMID: 16500306.
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    262. Burashnikov A, Antzelevitch C. Late-phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation. Pacing Clin Electrophysiol. 2006 Mar; 29(3):290-5. PMID: 16606397.
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    263. Vernooy K, Delhaas T, Cremer OL, Di Diego JM, Oliva A, Timmermans C, Volders PG, Prinzen FW, Crijns HJ, Antzelevitch C, Kalkman CJ, Rodriguez LM, Brugada R. Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. Heart Rhythm. 2006 Feb; 3(2):131-7. PMID: 16443524.
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    264. Antzelevitch C, Oliva A. Amplification of spatial dispersion of repolarization underlies sudden cardiac death associated with catecholaminergic polymorphic VT, long QT, short QT and Brugada syndromes. J Intern Med. 2006 Jan; 259(1):48-58. PMID: 16336513.
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    265. Antzelevitch C, Fish JM. Therapy for the Brugada syndrome. Handb Exp Pharmacol. 2006; (171):305-30. PMID: 16610350.
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    266. Fish JM, Brugada J, Antzelevitch C. Potential proarrhythmic effects of biventricular pacing. J Am Coll Cardiol. 2005 Dec 20; 46(12):2340-7. PMID: 16360069.
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    267. Antzelevitch C. Role of transmural dispersion of repolarization in the genesis of drug-induced torsades de pointes. Heart Rhythm. 2005 Nov; 2(2 Suppl):S9-15. PMID: 16253930.
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    268. Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH, Bruneau BG. The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell. 2005 Oct 21; 123(2):347-58. PMID: 16239150.
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    269. Viskin S, Antzelevitch C. The cardiologists' worst nightmare sudden death from "benign" ventricular arrhythmias. J Am Coll Cardiol. 2005 Oct 04; 46(7):1295-7. PMID: 16198846.
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    270. Borggrefe M, Wolpert C, Antzelevitch C, Veltmann C, Giustetto C, Gaita F, Schimpf R. Short QT syndrome. Genotype-phenotype correlations. J Electrocardiol. 2005 Oct; 38(4 Suppl):75-80. PMID: 16226079.
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    271. Di Diego JM, Fish JM, Antzelevitch C. Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences. J Electrocardiol. 2005 Oct; 38(4 Suppl):14-7. PMID: 16226068.
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    272. Antzelevitch C. Cardiac repolarization. The long and short of it. Europace. 2005 Sep; 7 Suppl 2:3-9. PMID: 16102498.
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    273. Viskin S, Rosso R, Rogowski O, Belhassen B, Levitas A, Wagshal A, Katz A, Fourey D, Zeltser D, Oliva A, Pollevick GD, Antzelevitch C, Rozovski U. Provocation of sudden heart rate oscillation with adenosine exposes abnormal QT responses in patients with long QT syndrome: a bedside test for diagnosing long QT syndrome. Eur Heart J. 2006 Feb; 27(4):469-75. PMID: 16105845.
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    274. Antzelevitch C. In vivo human demonstration of phase 2 reentry. Heart Rhythm. 2005 Aug; 2(8):804-6. PMID: 16051113.
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    275. P?rez Riera AR, Antzelevitch C, Schapacknik E, Dubner S, Ferreira C. Is there an overlap between Brugada syndrome and arrhythmogenic right ventricular cardiomyopathy/dysplasia? J Electrocardiol. 2005 Jul; 38(3):260-3. PMID: 16003713.
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    276. Antzelevitch C. Modulation of transmural repolarization. Ann N Y Acad Sci. 2005 Jun; 1047:314-23. PMID: 16093507.
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    277. Burashnikov A, Antzelevitch C. Role of repolarization restitution in the development of coarse and fine atrial fibrillation in the isolated canine right atria. J Cardiovasc Electrophysiol. 2005 Jun; 16(6):639-45. PMID: 15946365.
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    278. Francis J, Antzelevitch C. Brugada syndrome. Int J Cardiol. 2005 May 25; 101(2):173-8. PMID: 15882659.
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    279. Nam GB, Burashnikov A, Antzelevitch C. Cellular mechanisms underlying the development of catecholaminergic ventricular tachycardia. Circulation. 2005 May 31; 111(21):2727-33. PMID: 15911700.
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    280. Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A. Brugada syndrome: report of the second consensus conference. Heart Rhythm. 2005 Apr; 2(4):429-40. PMID: 15898165.
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    281. Wolpert C, Echternach C, Veltmann C, Antzelevitch C, Thomas GP, Spehl S, Streitner F, Kuschyk J, Schimpf R, Haase KK, Borggrefe M. Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome. Heart Rhythm. 2005 Mar; 2(3):254-60. PMID: 15851314.
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    282. Brugada P, Brugada R, Antzelevitch C, Brugada J. The Brugada Syndrome. Arch Mal Coeur Vaiss. 2005 Feb; 98(2):115-22. PMID: 15787302.
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    283. Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A. Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation. 2005 Feb 08; 111(5):659-70. PMID: 15655131.
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    284. Antzelevitch C, Brugada P, Brugada J, Brugada R. Brugada syndrome: from cell to bedside. Curr Probl Cardiol. 2005 Jan; 30(1):9-54. PMID: 15627121.
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    285. Wolpert C, Schimpf R, Giustetto C, Antzelevitch C, Cordeiro J, Dumaine R, Brugada R, Hong K, Bauersfeld U, Gaita F, Borggrefe M. Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG. J Cardiovasc Electrophysiol. 2005 Jan; 16(1):54-8. PMID: 15673388.
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    286. Shimizu W, Aiba T, Antzelevitch C. Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome. Curr Pharm Des. 2005; 11(12):1561-72. PMID: 15892662.
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    287. Hong K, Antzelevitch C, Brugada P, Brugada J, Ohe T, Brugada R. Brugada syndrome: 12 years of progression. Acta Med Okayama. 2004 Dec; 58(6):255-61. PMID: 15762293.
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    288. Extramiana F, Antzelevitch C. Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome. Circulation. 2004 Dec 14; 110(24):3661-6. PMID: 15569843.
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    289. Antzelevitch C. Molecular genetics of arrhythmias and cardiovascular conditions associated with arrhythmias. Heart Rhythm. 2004 Nov; 1(5 Suppl):42C-56C. PMID: 23570107.
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    290. Hong K, Brugada J, Oliva A, Berruezo-Sanchez A, Potenza D, Pollevick GD, Guerchicoff A, Matsuo K, Burashnikov E, Dumaine R, Towbin JA, Nesterenko V, Brugada P, Antzelevitch C, Brugada R. Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations. Circulation. 2004 Nov 09; 110(19):3023-7. PMID: 15520322.
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    291. Kondo M, Nesterenko V, Antzelevitch C. Cellular basis for the monophasic action potential. Which electrode is the recording electrode? Cardiovasc Res. 2004 Sep 01; 63(4):635-44. PMID: 15306219.
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    292. Antzelevitch C, Belardinelli L, Wu L, Fraser H, Zygmunt AC, Burashnikov A, Di Diego JM, Fish JM, Cordeiro JM, Goodrow RJ, Scornik F, Perez G. Electrophysiologic properties and antiarrhythmic actions of a novel antianginal agent. J Cardiovasc Pharmacol Ther. 2004 Sep; 9 Suppl 1:S65-83. PMID: 15378132.
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    293. Antzelevitch C, Belardinelli L, Zygmunt AC, Burashnikov A, Di Diego JM, Fish JM, Cordeiro JM, Thomas G. Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties. Circulation. 2004 Aug 24; 110(8):904-10. PMID: 15302796.
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    294. Fish JM, Antzelevitch C. Link between hypothermia and the Brugada syndrome. J Cardiovasc Electrophysiol. 2004 Aug; 15(8):942-4. PMID: 15333092.
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    295. Fish JM, Antzelevitch C. Role of sodium and calcium channel block in unmasking the Brugada syndrome. Heart Rhythm. 2004 Jul; 1(2):210-7. PMID: 15851155.
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    296. Burashnikov A, Mannava S, Antzelevitch C. Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block. Am J Physiol Heart Circ Physiol. 2004 Jun; 286(6):H2393-400. PMID: 15148061.
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    297. Gaita F, Giustetto C, Bianchi F, Schimpf R, Haissaguerre M, Cal? L, Brugada R, Antzelevitch C, Borggrefe M, Wolpert C. Short QT syndrome: pharmacological treatment. J Am Coll Cardiol. 2004 Apr 21; 43(8):1494-9. PMID: 15093889.
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    298. Fish JM, Di Diego JM, Nesterenko V, Antzelevitch C. Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing. Circulation. 2004 May 04; 109(17):2136-42. PMID: 15078801.
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    299. Antzelevitch C, Francis J. Congenital short QT syndrome. Indian Pacing Electrophysiol J. 2004 Apr 01; 4(2):46-9. PMID: 16943970.
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    300. Fenichel RR, Malik M, Antzelevitch C, Sanguinetti M, Roden DM, Priori SG, Ruskin JN, Lipicky RJ, Cantilena LR. Drug-induced torsades de pointes and implications for drug development. J Cardiovasc Electrophysiol. 2004 Apr; 15(4):475-95. PMID: 15090000.
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    301. Wu L, Shryock JC, Song Y, Li Y, Antzelevitch C, Belardinelli L. Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome. J Pharmacol Exp Ther. 2004 Aug; 310(2):599-605. PMID: 15031300.
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    302. Viskin S, Zelster D, Antzelevitch C. When u say "U Waves," what do u mean? Pacing Clin Electrophysiol. 2004 Feb; 27(2):145-7. PMID: 14764163.
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    303. Verrier RL, Antzelevitch C. Autonomic aspects of arrhythmogenesis: the enduring and the new. Curr Opin Cardiol. 2004 Jan; 19(1):2-11. PMID: 14688627.
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    304. Antzelevitch C. Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem? J Electrocardiol. 2004; 37 Suppl:15-24. PMID: 15534788.
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    305. Antzelevitch C. Cellular basis and mechanism underlying normal and abnormal myocardial repolarization and arrhythmogenesis. Ann Med. 2004; 36 Suppl 1:5-14. PMID: 15176418.
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    306. Hong K, Berruezo-Sanchez A, Poungvarin N, Oliva A, Vatta M, Brugada J, Brugada P, Towbin JA, Dumaine R, Pi?ero-Galvez C, Antzelevitch C, Brugada R. Phenotypic characterization of a large European family with Brugada syndrome displaying a sudden unexpected death syndrome mutation in SCN5A:. J Cardiovasc Electrophysiol. 2004 Jan; 15(1):64-9. PMID: 15028074.
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    307. Brugada R, Hong K, Dumaine R, Cordeiro J, Gaita F, Borggrefe M, Menendez TM, Brugada J, Pollevick GD, Wolpert C, Burashnikov E, Matsuo K, Wu YS, Guerchicoff A, Bianchi F, Giustetto C, Schimpf R, Brugada P, Antzelevitch C. Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation. 2004 Jan 06; 109(1):30-5. PMID: 14676148.
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    308. Cordeiro JM, Greene L, Heilmann C, Antzelevitch D, Antzelevitch C. Transmural heterogeneity of calcium activity and mechanical function in the canine left ventricle. Am J Physiol Heart Circ Physiol. 2004 Apr; 286(4):H1471-9. PMID: 14670817.
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    309. Belardinelli L, Antzelevitch C, Vos MA. Assessing predictors of drug-induced torsade de pointes. Trends Pharmacol Sci. 2003 Dec; 24(12):619-25. PMID: 14654302.
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    310. Antzelevitch C. Molecular genetics of arrhythmias and cardiovascular conditions associated with arrhythmias. Pacing Clin Electrophysiol. 2003 Nov; 26(11):2194-208. PMID: 14622329.
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    311. Antzelevitch C. Molecular genetics of arrhythmias and cardiovascular conditions associated with arrhythmias. J Cardiovasc Electrophysiol. 2003 Nov; 14(11):1259-72. PMID: 14678150.
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    312. Di Diego JM, Belardinelli L, Antzelevitch C. Cisapride-induced transmural dispersion of repolarization and torsade de pointes in the canine left ventricular wedge preparation during epicardial stimulation. Circulation. 2003 Aug 26; 108(8):1027-33. PMID: 12912819.
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    313. Francis J, Antzelevitch C. Brugada-like electrocardiographic pattern. Indian Pacing Electrophysiol J. 2003 Jul 01; 3(3):91-2. PMID: 16943906.
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    314. Antzelevitch C. Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects. Expert Rev Cardiovasc Ther. 2003 Jul; 1(2):177-85. PMID: 15030278.
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    315. Antzelevitch C. Androgens and male predominance of the Brugada syndrome phenotype. Pacing Clin Electrophysiol. 2003 Jul; 26(7 Pt 1):1429-31. PMID: 12914617.
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    316. Antzelevitch C, Brugada P, Brugada J, Brugada R, Towbin JA, Nademanee K. Brugada syndrome: 1992-2002: a historical perspective. J Am Coll Cardiol. 2003 May 21; 41(10):1665-71. PMID: 12767644.
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    317. Burashnikov A, Antzelevitch C. Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity. Circulation. 2003 May 13; 107(18):2355-60. PMID: 12695296.
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    318. Medina-Ravell VA, Lankipalli RS, Yan GX, Antzelevitch C, Medina-Malpica NA, Medina-Malpica OA, Droogan C, Kowey PR. Effect of epicardial or biventricular pacing to prolong QT interval and increase transmural dispersion of repolarization: does resynchronization therapy pose a risk for patients predisposed to long QT or torsade de pointes? Circulation. 2003 Feb 11; 107(5):740-6. PMID: 12578878.
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    319. Ramakers C, Vos MA, Doevendans PA, Schoenmakers M, Wu YS, Scicchitano S, Iodice A, Thomas GP, Antzelevitch C, Dumaine R. Coordinated down-regulation of KCNQ1 and KCNE1 expression contributes to reduction of I(Ks) in canine hypertrophied hearts. Cardiovasc Res. 2003 Feb; 57(2):486-96. PMID: 12566121.
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    320. Fish JM, Antzelevitch C. Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes. J Electrocardiol. 2003; 36 Suppl:173-9. PMID: 14716629.
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    321. Di Diego JM, Antzelevitch C. Cellular basis for ST-segment changes observed during ischemia. J Electrocardiol. 2003; 36 Suppl:1-5. PMID: 14716579.
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    322. Thomas GP, Gerlach U, Antzelevitch C. HMR 1556, a potent and selective blocker of slowly activating delayed rectifier potassium current. J Cardiovasc Pharmacol. 2003 Jan; 41(1):140-7. PMID: 12500032.
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    324. Antzelevitch C, Brugada P, Brugada J, Brugada R, Shimizu W, Gussak I, Perez Riera AR. Brugada syndrome: a decade of progress. Circ Res. 2002 Dec 13; 91(12):1114-8. PMID: 12480811.
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    325. Wilde AA, Antzelevitch C, Borggrefe M, Brugada J, Brugada R, Brugada P, Corrado D, Hauer RN, Kass RS, Nademanee K, Priori SG, Towbin JA. Proposed diagnostic criteria for the Brugada syndrome: consensus report. Circulation. 2002 Nov 05; 106(19):2514-9. PMID: 12417552.
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    326. Antzelevitch C, Brugada R. Fever and Brugada syndrome. Pacing Clin Electrophysiol. 2002 Nov; 25(11):1537-9. PMID: 12494608.
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    327. Wilde AA, Antzelevitch C, Borggrefe M, Brugada J, Brugada R, Brugada P, Corrado D, Hauer RN, Kass RS, Nademanee K, Priori SG, Towbin JA. Proposed diagnostic criteria for the Brugada syndrome. Eur Heart J. 2002 Nov; 23(21):1648-54. PMID: 12448445.
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    328. Belhassen B, Viskin S, Antzelevitch C. The Brugada syndrome: is an implantable cardioverter defibrillator the only therapeutic option? Pacing Clin Electrophysiol. 2002 Nov; 25(11):1634-40. PMID: 12494624.
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    329. Di Diego JM, Cordeiro JM, Goodrow RJ, Fish JM, Zygmunt AC, P?rez GJ, Scornik FS, Antzelevitch C. Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males. Circulation. 2002 Oct 08; 106(15):2004-11. PMID: 12370227.
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    330. Antzelevitch C. Sympathetic modulation of the long QT syndrome. Eur Heart J. 2002 Aug; 23(16):1246-52. PMID: 12175662.
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    331. Antzelevitch C. Late potentials and the Brugada syndrome. J Am Coll Cardiol. 2002 Jun 19; 39(12):1996-9. PMID: 12084599.
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    332. Antzelevitch C. Brugada syndrome: historical perspectives and observations. Eur Heart J. 2002 Apr; 23(8):676-8. PMID: 11969284.
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    333. Vatta M, Dumaine R, Antzelevitch C, Brugada R, Li H, Bowles NE, Nademanee K, Brugada J, Brugada P, Towbin JA. Novel mutations in domain I of SCN5A cause Brugada syndrome. Mol Genet Metab. 2002 Apr; 75(4):317-24. PMID: 12051963.
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    334. Akar FG, Yan GX, Antzelevitch C, Rosenbaum DS. Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome. Circulation. 2002 Mar 12; 105(10):1247-53. PMID: 11889021.
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    335. Vatta M, Dumaine R, Varghese G, Richard TA, Shimizu W, Aihara N, Nademanee K, Brugada R, Brugada J, Veerakul G, Li H, Bowles NE, Brugada P, Antzelevitch C, Towbin JA. Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome. Hum Mol Genet. 2002 Feb 01; 11(3):337-45. PMID: 11823453.
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    336. Gussak I, Brugada P, Brugada J, Antzelevitch C, Osbakken M, Bjerregaard P. ECG phenomenon of idiopathic and paradoxical short QT intervals. Card Electrophysiol Rev. 2002 Feb; 6(1-2):49-53. PMID: 11984017.
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    337. Burashnikov A, Antzelevitch C. Prominent I(Ks) in epicardium and endocardium contributes to development of transmural dispersion of repolarization but protects against development of early afterdepolarizations. J Cardiovasc Electrophysiol. 2002 Feb; 13(2):172-7. PMID: 11900293.
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    338. Dumaine R, Antzelevitch C. Molecular mechanisms underlying the long QT syndrome. Curr Opin Cardiol. 2002 Jan; 17(1):36-42. PMID: 11790932.
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    339. Naccarelli GV, Antzelevitch C, Wolbrette DL, Luck JC. The Brugada syndrome. Curr Opin Cardiol. 2002 Jan; 17(1):19-23. PMID: 11790929.
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    340. Antzelevitch C, Shimizu W. Cellular mechanisms underlying the long QT syndrome. Curr Opin Cardiol. 2002 Jan; 17(1):43-51. PMID: 11790933.
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    341. Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P. Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3. Circulation. 2002 Jan 01; 105(1):73-8. PMID: 11772879.
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    342. Emori T, Antzelevitch C. Cellular basis for complex T waves and arrhythmic activity following combined I(Kr) and I(Ks) block. J Cardiovasc Electrophysiol. 2001 Dec; 12(12):1369-78. PMID: 11797994.
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    343. Link MS, Antzelevitch C, Waldo AL, Grant AO, DiMarco JP, Josephson ME, Marchlinski FE, Garan H, Sager PT, Reynolds DW, Denes P, Scheinman MM, Estes NA. Clinical cardiac electrophysiology fellowship teaching objectives for the new millennium. J Cardiovasc Electrophysiol. 2001 Dec; 12(12):1433-43. PMID: 11798006.
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    344. Antzelevitch C, Fish J. Electrical heterogeneity within the ventricular wall. Basic Res Cardiol. 2001 Nov; 96(6):517-27. PMID: 11770069.
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    345. Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF. Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct; 52(1):65-75. PMID: 11557234.
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    346. Zygmunt AC, Eddlestone GT, Thomas GP, Nesterenko VV, Antzelevitch C. Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle. Am J Physiol Heart Circ Physiol. 2001 Aug; 281(2):H689-97. PMID: 11454573.
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    347. Antzelevitch C. T peak-Tend interval as an index of transmural dispersion of repolarization. Eur J Clin Invest. 2001 Jul; 31(7):555-7. PMID: 11454006.
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    349. Antzelevitch C. Molecular basis for the transmural distribution of the transient outward current. J Physiol. 2001 May 15; 533(Pt 1):1. PMID: 11351005.
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    350. Naccarelli GV, Antzelevitch C. The Brugada syndrome: clinical, genetic, cellular, and molecular abnormalities. Am J Med. 2001 May; 110(7):573-81. PMID: 11343671.
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    351. Sun ZQ, Thomas GP, Antzelevitch C. Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes. J Cardiovasc Electrophysiol. 2001 Apr; 12(4):472-8. PMID: 11332571.
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    352. Antzelevitch C. The Brugada syndrome: diagnostic criteria and cellular mechanisms. Eur Heart J. 2001 Mar; 22(5):356-63. PMID: 11207076.
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    353. Antzelevitch C. The Brugada syndrome: ionic basis and arrhythmia mechanisms. J Cardiovasc Electrophysiol. 2001 Feb; 12(2):268-72. PMID: 11232628.
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    354. Antzelevitch C. Basic mechanisms of reentrant arrhythmias. Curr Opin Cardiol. 2001 Jan; 16(1):1-7. PMID: 11124712.
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    355. Antzelevitch C. Molecular biology and cellular mechanisms of Brugada and long QT syndromes in infants and young children. J Electrocardiol. 2001; 34 Suppl:177-81. PMID: 11781953.
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    356. Shimizu W, Antzelevitch C, Suyama K, Kurita T, Taguchi A, Aihara N, Takaki H, Sunagawa K, Kamakura S. Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. J Cardiovasc Electrophysiol. 2000 Dec; 11(12):1320-9. PMID: 11196553.
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    357. Antzelevitch C. Electrical heterogeneity, cardiac arrhythmias, and the sodium channel. Circ Res. 2000 Nov 24; 87(11):964-5. PMID: 11090538.
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    358. Gussak I, Antzelevitch C. Early repolarization syndrome: clinical characteristics and possible cellular and ionic mechanisms. J Electrocardiol. 2000 Oct; 33(4):299-309. PMID: 11099355.
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    359. Shimizu W, Antzelevitch C. Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome. Circulation. 2000 Aug 08; 102(6):706-12. PMID: 10931813.
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    360. Haverkamp W, Breithardt G, Camm AJ, Janse MJ, Rosen MR, Antzelevitch C, Escande D, Franz M, Malik M, Moss A, Shah R. The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology. Eur Heart J. 2000 Aug; 21(15):1216-31. PMID: 10924311.
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    361. Haverkamp W, Breithardt G, Camm AJ, Janse MJ, Rosen MR, Antzelevitch C, Escande D, Franz M, Malik M, Moss A, Shah R. The potential for QT prolongation and pro-arrhythmia by non-anti-arrhythmic drugs: clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology. Cardiovasc Res. 2000 Aug; 47(2):219-33. PMID: 10947683.
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    362. Schwartz PJ, Priori SG, Dumaine R, Napolitano C, Antzelevitch C, Stramba-Badiale M, Richard TA, Berti MR, Bloise R. A molecular link between the sudden infant death syndrome and the long-QT syndrome. N Engl J Med. 2000 Jul 27; 343(4):262-7. PMID: 10911008.
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    363. Zygmunt AC, Goodrow RJ, Antzelevitch C. I(NaCa) contributes to electrical heterogeneity within the canine ventricle. Am J Physiol Heart Circ Physiol. 2000 May; 278(5):H1671-8. PMID: 10775148.
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    364. Burashnikov A, Antzelevitch C. Block of I(Ks) does not induce early afterdepolarization activity but promotes beta-adrenergic agonist-induced delayed afterdepolarization activity. J Cardiovasc Electrophysiol. 2000 Apr; 11(4):458-65. PMID: 10809500.
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    365. Shimizu W, Antzelevitch C. Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome. J Am Coll Cardiol. 2000 Mar 01; 35(3):778-86. PMID: 10716483.
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    366. Weissenburger J, Nesterenko VV, Antzelevitch C. Transmural heterogeneity of ventricular repolarization under baseline and long QT conditions in the canine heart in vivo: torsades de pointes develops with halothane but not pentobarbital anesthesia. J Cardiovasc Electrophysiol. 2000 Mar; 11(3):290-304. PMID: 10749352.
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    367. Brugada R, Brugada J, Antzelevitch C, Kirsch GE, Potenza D, Towbin JA, Brugada P. Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts. Circulation. 2000 Feb 08; 101(5):510-5. PMID: 10662748.
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    368. Antzelevitch C, Yan GX. Cellular and ionic mechanisms responsible for the Brugada syndrome. J Electrocardiol. 2000; 33 Suppl:33-9. PMID: 11265734.
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    369. Dumaine R, Towbin JA, Brugada P, Vatta M, Nesterenko DV, Nesterenko VV, Brugada J, Brugada R, Antzelevitch C. Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent. Circ Res. 1999 Oct 29; 85(9):803-9. PMID: 10532948.
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    370. Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation. 1999 Oct 12; 100(15):1660-6. PMID: 10517739.
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    371. Burashnikov A, Antzelevitch C. Differences in the electrophysiologic response of four canine ventricular cell types to alpha 1-adrenergic agonists. Cardiovasc Res. 1999 Sep; 43(4):901-8. PMID: 10615417.
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    372. Antzelevitch C, Shimizu W, Yan GX, Sicouri S, Weissenburger J, Nesterenko VV, Burashnikov A, Di Diego J, Saffitz J, Thomas GP. The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart. J Cardiovasc Electrophysiol. 1999 Aug; 10(8):1124-52. PMID: 10466495.
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    373. Antzelevitch C. Ion channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome. Curr Opin Cardiol. 1999 May; 14(3):274-9. PMID: 10358800.
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    374. Thomas GP, Karmazyn M, Zygmunt AC, Antzelevitch C, Narayanan N. The antifungal antibiotic clotrimazole potently inhibits L-type calcium current in guinea-pig ventricular myocytes. Br J Pharmacol. 1999 Apr; 126(7):1531-3. PMID: 10323582.
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    375. Shimizu W, Antzelevitch C. Cellular and ionic basis for T-wave alternans under long-QT conditions. Circulation. 1999 Mar 23; 99(11):1499-507. PMID: 10086976.
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    376. Shimizu W, McMahon B, Antzelevitch C. Sodium pentobarbital reduces transmural dispersion of repolarization and prevents torsades de Pointes in models of acquired and congenital long QT syndrome. J Cardiovasc Electrophysiol. 1999 Feb; 10(2):154-64. PMID: 10090218.
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    377. Gussak I, Antzelevitch C, Bjerregaard P, Towbin JA, Chaitman BR. The Brugada syndrome: clinical, electrophysiologic and genetic aspects. J Am Coll Cardiol. 1999 Jan; 33(1):5-15. PMID: 9935001.
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    378. Shimizu W, Antzelevitch C. Cellular basis for long QT, transmural dispersion of repolarization, and torsade de pointes in the long QT syndrome. J Electrocardiol. 1999; 32 Suppl:177-84. PMID: 10688323.
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    379. Shimizu W, Antzelevitch C. Differential response of transmural dispersion of repolarization and torsade de pointes to beta-adrenergic agonists and antagonists in three models of the long QT syndrome. J Electrocardiol. 1999; 32 Suppl:150. PMID: 10688318.
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    380. Antzelevitch C, Yan GX, Shimizu W. Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome. J Electrocardiol. 1999; 32 Suppl:158-65. PMID: 10688320.
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    381. Shimizu W, Antzelevitch C. Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes. Circulation. 1998 Nov 24; 98(21):2314-22. PMID: 9826320.
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    382. Yan GX, Shimizu W, Antzelevitch C. Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations. Circulation. 1998 Nov 03; 98(18):1921-7. PMID: 9799214.
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    383. Yan GX, Antzelevitch C. Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation. 1998 Nov 03; 98(18):1928-36. PMID: 9799215.
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    384. Burashnikov A, Antzelevitch C. Acceleration-induced action potential prolongation and early afterdepolarizations. J Cardiovasc Electrophysiol. 1998 Sep; 9(9):934-48. PMID: 9786074.
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    385. Antzelevitch C. The Brugada syndrome. J Cardiovasc Electrophysiol. 1998 May; 9(5):513-6. PMID: 9607460.
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    386. Chen Q, Kirsch GE, Zhang D, Brugada R, Brugada J, Brugada P, Potenza D, Moya A, Borggrefe M, Breithardt G, Ortiz-Lopez R, Wang Z, Antzelevitch C, O'Brien RE, Schulze-Bahr E, Keating MT, Towbin JA, Wang Q. Genetic basis and molecular mechanism for idiopathic ventricular fibrillation. Nature. 1998 Mar 19; 392(6673):293-6. PMID: 9521325.
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    387. Antzelevitch C, Shimizu W, Yan GX, Sicouri S. Cellular basis for QT dispersion. J Electrocardiol. 1998; 30 Suppl:168-75. PMID: 9535495.
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    388. Bjerregaard P, Gussak I, Antzelevitch C. The enigmatic ECG manifestation of Brugada syndrome. J Cardiovasc Electrophysiol. 1998 Jan; 9(1):109-12. PMID: 9475586.
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    389. Sicouri S, Antzelevitch D, Heilmann C, Antzelevitch C. Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome. J Cardiovasc Electrophysiol. 1997 Nov; 8(11):1280-90. PMID: 9395171.
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    390. Sicouri S, Moro S, Litovsky S, Elizari MV, Antzelevitch C. Chronic amiodarone reduces transmural dispersion of repolarization in the canine heart. J Cardiovasc Electrophysiol. 1997 Nov; 8(11):1269-79. PMID: 9395170.
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    391. Antzelevitch C. Are M cells present in the ventricular myocardium of the pig? A question of maturity. Cardiovasc Res. 1997 Oct; 36(1):127-8. PMID: 9415281.
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    392. Shimizu W, Antzelevitch C. Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome. Circulation. 1997 Sep 16; 96(6):2038-47. PMID: 9323097.
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    393. Zygmunt AC, Goodrow RJ, Antzelevitch C. Sodium effects on 4-aminopyridine-sensitive transient outward current in canine ventricular cells. Am J Physiol. 1997 Jan; 272(1 Pt 2):H1-11. PMID: 9038916.
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    394. Antzelevitch C, Sun ZQ, Zhang ZQ, Yan GX. Cellular and ionic mechanisms underlying erythromycin-induced long QT intervals and torsade de pointes. J Am Coll Cardiol. 1996 Dec; 28(7):1836-48. PMID: 8962574.
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    395. Lukas A, Antzelevitch C. Phase 2 reentry as a mechanism of initiation of circus movement reentry in canine epicardium exposed to simulated ischemia. Cardiovasc Res. 1996 Sep; 32(3):593-603. PMID: 8881520.
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    396. Di Diego JM, Sun ZQ, Antzelevitch C. I(to) and action potential notch are smaller in left vs. right canine ventricular epicardium. Am J Physiol. 1996 Aug; 271(2 Pt 2):H548-61. PMID: 8770096.
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    397. Sicouri S, Quist M, Antzelevitch C. Evidence for the presence of M cells in the guinea pig ventricle. J Cardiovasc Electrophysiol. 1996 Jun; 7(6):503-11. PMID: 8743756.
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    398. Yan GX, Antzelevitch C. Cellular basis for the electrocardiographic J wave. Circulation. 1996 Jan 15; 93(2):372-9. PMID: 8548912.
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    399. Sicouri S, Antzelevitch C. Electrophysiologic characteristics of M cells in the canine left ventricular free wall. J Cardiovasc Electrophysiol. 1995 Aug; 6(8):591-603. PMID: 8535556.
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    400. Liu DW, Antzelevitch C. Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell. Circ Res. 1995 Mar; 76(3):351-65. PMID: 7859382.
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    401. Antzelevitch C, Nesterenko VV, Yan GX. Role of M cells in acquired long QT syndrome, U waves, and torsade de pointes. J Electrocardiol. 1995; 28 Suppl:131-8. PMID: 8656100.
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    402. Sicouri S, Fish J, Antzelevitch C. Distribution of M cells in the canine ventricle. J Cardiovasc Electrophysiol. 1994 Oct; 5(10):824-37. PMID: 7874328.
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    403. Di Diego JM, Antzelevitch C. High [Ca2+]o-induced electrical heterogeneity and extrasystolic activity in isolated canine ventricular epicardium. Phase 2 reentry. Circulation. 1994 Apr; 89(4):1839-50. PMID: 7511994.
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    404. Antzelevitch C, Sicouri S. Clinical relevance of cardiac arrhythmias generated by afterdepolarizations. Role of M cells in the generation of U waves, triggered activity and torsade de pointes. J Am Coll Cardiol. 1994 Jan; 23(1):259-77. PMID: 8277090.
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    405. Lukas A, Antzelevitch C. Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia. Role of the transient outward current. Circulation. 1993 Dec; 88(6):2903-15. PMID: 8252704.
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    406. Di Diego JM, Antzelevitch C. Pinacidil-induced electrical heterogeneity and extrasystolic activity in canine ventricular tissues. Does activation of ATP-regulated potassium current promote phase 2 reentry? Circulation. 1993 Sep; 88(3):1177-89. PMID: 7689041.
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    407. Ofosu-Appiah W, Ruggiero C, Dzielak DJ, Antzelevitch C. The effects of PEG-interleukin-2 and interleukin-2 on essential hypertension and cellular immune function in the spontaneously hypertensive rat. Clin Exp Hypertens. 1993 Mar; 15(2):435-57. PMID: 8467327.
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    408. Liu DW, Gintant GA, Antzelevitch C. Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle. Circ Res. 1993 Mar; 72(3):671-87. PMID: 8431990.
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    409. Krishnan SC, Antzelevitch C. Flecainide-induced arrhythmia in canine ventricular epicardium. Phase 2 reentry? Circulation. 1993 Feb; 87(2):562-72. PMID: 8425300.
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    410. Sicouri S, Antzelevitch C. Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells (M cells) in the canine heart: quinidine and digitalis. J Cardiovasc Electrophysiol. 1993 Feb; 4(1):48-58. PMID: 8287236.
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    411. Antzelevitch C, Di Diego JM. Role of K+ channel activators in cardiac electrophysiology and arrhythmias. Circulation. 1992 Apr; 85(4):1627-9. PMID: 1555302.
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    412. Antzelevitch C, Sicouri S, Litovsky SH, Lukas A, Krishnan SC, Di Diego JM, Gintant GA, Liu DW. Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ Res. 1991 Dec; 69(6):1427-49. PMID: 1659499.
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    413. Sicouri S, Antzelevitch C. Afterdepolarizations and triggered activity develop in a select population of cells (M cells) in canine ventricular myocardium: the effects of acetylstrophanthidin and Bay K 8644. Pacing Clin Electrophysiol. 1991 Nov; 14(11 Pt 2):1714-20. PMID: 1721163.
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    414. Krishnan SC, Antzelevitch C. Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium. Circ Res. 1991 Aug; 69(2):277-91. PMID: 1650294.
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    415. Sicouri S, Antzelevitch C. A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell. Circ Res. 1991 Jun; 68(6):1729-41. PMID: 2036721.
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    416. Litovsky SH, Antzelevitch C. Differences in the electrophysiological response of canine ventricular subendocardium and subepicardium to acetylcholine and isoproterenol. A direct effect of acetylcholine in ventricular myocardium. Circ Res. 1990 Sep; 67(3):615-27. PMID: 2397572.
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    417. Litovsky SH, Antzelevitch C. Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: role of the transient outward current. J Am Coll Cardiol. 1989 Oct; 14(4):1053-66. PMID: 2551947.
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    418. Lukas A, Antzelevitch C. Reflected reentry, delayed conduction, and electrotonic inhibition in segmentally depressed atrial tissues. Can J Physiol Pharmacol. 1989 Jul; 67(7):757-64. PMID: 2766107.
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    419. Davidenko JM, Cohen L, Goodrow R, Antzelevitch C. Quinidine-induced action potential prolongation, early afterdepolarizations, and triggered activity in canine Purkinje fibers. Effects of stimulation rate, potassium, and magnesium. Circulation. 1989 Mar; 79(3):674-86. PMID: 2917391.
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    420. Litovsky SH, Antzelevitch C. Transient outward current prominent in canine ventricular epicardium but not endocardium. Circ Res. 1988 Jan; 62(1):116-26. PMID: 2826039.
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    421. Moe GK, Antzelevitch C. Reflection as a mechanism of reentrant cardiac arrhythmias. Physiol Bohemoslov. 1987; 36(3):243-53. PMID: 2442783.
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    422. Shen XT, Antzelevitch C. Mechanisms underlying the antiarrhythmic and arrhythmogenic actions of quinidine in a Purkinje fiber-ischemic gap preparation of reflected reentry. Circulation. 1986 Jun; 73(6):1342-53. PMID: 3698260.
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    423. Davidenko JM, Antzelevitch C. Electrophysiological mechanisms underlying rate-dependent changes of refractoriness in normal and segmentally depressed canine Purkinje fibers. The characteristics of post-repolarization refractoriness. Circ Res. 1986 Feb; 58(2):257-68. PMID: 3948343.
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    424. Reiner VS, Antzelevitch C. Phase resetting and annihilation in a mathematical model of sinus node. Am J Physiol. 1985 Dec; 249(6 Pt 2):H1143-53. PMID: 4073283.
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    425. Davidenko J, Antzelevitch C. The effects of milrinone on action potential characteristics, conduction, automaticity, and reflected reentry in isolated myocardial fibers. J Cardiovasc Pharmacol. 1985 Mar-Apr; 7(2):341-9. PMID: 2581090.
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    426. Davidenko JM, Antzelevitch C. The effects of milrinone on conduction, reflection, and automaticity in canine Purkinje fibers. Circulation. 1984 May; 69(5):1026-35. PMID: 6705158.
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    427. Antzelevitch C, Bernstein MJ, Feldman HN, Moe GK. Parasystole, reentry, and tachycardia: a canine preparation of cardiac arrhythmias occurring across inexcitable segments of tissue. Circulation. 1983 Nov; 68(5):1101-15. PMID: 6193902.
      Citations:    
    428. Antzelevitch C, Moe GK. Electrotonic inhibition and summation of impulse conduction in mammalian Purkinje fibers. Am J Physiol. 1983 Jul; 245(1):H42-53. PMID: 6869562.
      Citations:    
    429. Jalife J, Antzelevitch C, Lamanna V, Moe GK. Rate-dependent changes in excitability of depressed cardiac Purkinje fibers as a mechanism of intermittent bundle branch block. Circulation. 1983 Apr; 67(4):912-22. PMID: 6825248.
      Citations:    
    430. Antzelevitch C. Clinical application of new concepts of parasystole, reflection, and tachycardia. Cardiol Clin. 1983 Feb; 1(1):39-50. PMID: 6399992.
      Citations:    
    431. Antzelevitch C, Jalife J, Moe GK. Electrotonic metabolism of pacemaker activity. Further biological and mathematical observations on the behavior of modulated parasystole. Circulation. 1982 Dec; 66(6):1225-32. PMID: 7139901.
      Citations:    
    432. Jalife J, Antzelevitch C, Moe GK. The case for modulated parasystole. Pacing Clin Electrophysiol. 1982 Nov; 5(6):911-26. PMID: 6184694.
      Citations:    
    433. Moe GK, Jalife J, Antzelevitch C. Models of parasystole and reentry in isolated Purkinje fibers. Mayo Clin Proc. 1982 Jul; 57 Suppl:14-9. PMID: 7121077.
      Citations:    
    434. Lamanna V, Antzelevitch C, Moe GK. Effects of lidocaine on conduction through depolarized canine false tendons and on a model of reflected reentry. J Pharmacol Exp Ther. 1982 May; 221(2):353-61. PMID: 7077530.
      Citations:    
    435. Antzelevitch C, Moe GK. Electrotonically mediated delayed conduction and reentry in relation to "slow responses" in mammalian ventricular conducting tissue. Circ Res. 1981 Nov; 49(5):1129-39. PMID: 7296780.
      Citations:    
    436. Jalife J, Antzelevitch C. Pacemaker annihilation: diagnostic and therapeutic implications. Am Heart J. 1980 Jul; 100(1):128-30. PMID: 7386358.
      Citations:    
    437. Antzelevitch C, Jalife J, Moe GK. Characteristics of reflection as a mechanism of reentrant arrhythmias and its relationship to parasystole. Circulation. 1980 Jan; 61(1):182-91. PMID: 7349933.
      Citations:    
    438. Jalife J, Antzelevitch C. Phase resetting and annihilation of pacemaker activity in cardiac tissue. Science. 1979 Nov 09; 206(4419):695-7. PMID: 493975.
      Citations:    
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