Thomas Jefferson University

Peter Le Roux

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19023
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    K08NS001975     (LE ROUX, PETER D)Jul 23, 1997 - Jun 30, 2003
    NIH
    ASTROCYTE MEDIATED NEURON SURVIVAL AND PROCESS GROWTH
    Role: Principal Investigator
    R01NS061860     (MADDEN, CHRISTOPHER)Sep 30, 2009 - Aug 31, 2014
    NIH
    Phase II, randomized controlled trial of brain tissue oxygen monitoring
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Susa S, Rahmani R, Conover D, Carr S, Ellens N, Proper D, Le Roux P, Catapano J, Srinivasan V, Bhalla T. Safety of the Mobile Stroke Unit: A Descriptive Review and Results of Radiation Monitoring. Stroke. 2021 08; 52(8):e497-e498. PMID: 34082572.
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    2. Le Roux P. Evolution of neurocritical care. Curr Opin Crit Care. 2020 04; 26(2):83-86. PMID: 32022728.
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    3. Bhalla T, Rahmani R, Le Roux P. Mobile stroke units: taking stroke care to the patient. Curr Opin Crit Care. 2020 04; 26(2):87-96. PMID: 32068579.
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    4. Vitt JR, Sun CH, Le Roux PD, Hemphill JC. Minimally invasive surgery for intracerebral hemorrhage. Curr Opin Crit Care. 2020 04; 26(2):129-136. PMID: 32004194.
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    5. Merck LH, Yeatts SD, Silbergleit R, Manley GT, Pauls Q, Palesch Y, Conwit R, Le Roux P, Miller J, Frankel M, Wright DW. The Effect of Goal-Directed Therapy on Patient Morbidity and Mortality After Traumatic Brain Injury: Results From the Progesterone for the Treatment of Traumatic Brain Injury III Clinical Trial. Crit Care Med. 2019 05; 47(5):623-631. PMID: 30730438.
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    6. Jaja BNR, Schweizer TA, Claassen J, Le Roux P, Mayer SA, Macdonald RL. The SAFARI Score to Assess the Risk of Convulsive Seizure During Admission for Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2018 06 01; 82(6):887-893. PMID: 28973169.
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    7. Doerfler S, Faerber J, McKhann GM, Elliott JP, Winn HR, Kumar M, Levine J, Le Roux PD. The Incidence and Impact of Secondary Cerebral Insults on Outcome After Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2018 Jun; 114:e483-e494. PMID: 29574224.
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    8. Jaja BNR, Saposnik G, Lingsma HF, Macdonald E, Thorpe KE, Mamdani M, Steyerberg EW, Molyneux A, Manoel ALO, Schatlo B, Hanggi D, Hasan D, Wong GKC, Etminan N, Fukuda H, Torner J, Schaller KL, Suarez JI, Stienen MN, Vergouwen MDI, Rinkel GJE, Spears J, Cusimano MD, Todd M, Le Roux P, Kirkpatrick P, Pickard J, van den Bergh WM, Murray G, Johnston SC, Yamagata S, Mayer S, Schweizer TA, Macdonald RL. Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study. BMJ. 2018 01 18; 360:j5745. PMID: 29348138.
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    9. Kumar MA, Levine J, Faerber J, Elliott JP, Winn HR, Doerfler S, Le Roux P. The Effects of Red Blood Cell Transfusion on Functional Outcome after Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2017 Dec; 108:807-816. PMID: 29038077.
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    10. Hutchinson PJ, Jalloh I, Helmy A, Carpenter KL, Rostami E, Bellander BM, Boutelle MG, Chen JW, Claassen J, Dahyot-Fizelier C, Enblad P, Gallagher CN, Helbok R, Hillered L, Le Roux PD, Magnoni S, Mangat HS, Menon DK, Nordstr?m CH, O'Phelan KH, Oddo M, Perez Barcena J, Robertson C, Ronne-Engstr?m E, Sahuquillo J, Smith M, Stocchetti N, Belli A, Carpenter TA, Coles JP, Czosnyka M, Dizdar N, Goodman JC, Gupta AK, Nielsen TH, Marklund N, Montcriol A, O'Connell MT, Poca MA, Sarrafzadeh A, Shannon RJ, Skj?th-Rasmussen J, Smielewski P, Stover JF, Timofeev I, Vespa P, Zavala E, Ungerstedt U. Consensus statement from the 2014 International Microdialysis Forum. Intensive Care Med. 2015 Sep; 41(9):1517-28. PMID: 26194024.
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    11. Chesnut RM, Bleck TP, Citerio G, Classen J, Cooper DJ, Coplin WM, Diringer MN, Gr?nde PO, Hemphill JC, Hutchinson PJ, Le Roux P, Mayer SA, Menon DK, Myburgh JA, Okonkwo DO, Robertson CS, Sahuquillo J, Stocchetti N, Sung G, Temkin N, Vespa PM, Videtta W, Yonas H. A Consensus-Based Interpretation of the Benchmark Evidence from South American Trials: Treatment of Intracranial Pressure Trial. J Neurotrauma. 2015 Nov 15; 32(22):1722-4. PMID: 26061135.
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    12. Citerio G, Park S, Schmidt JM, Moberg R, Suarez JI, Le Roux PD. Data collection and interpretation. Neurocrit Care. 2015 Jun; 22(3):360-8. PMID: 25846711.
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    13. Stocchetti N, Taccone FS, Citerio G, Pepe PE, Le Roux PD, Oddo M, Polderman KH, Stevens RD, Barsan W, Maas AI, Meyfroidt G, Bell MJ, Silbergleit R, Vespa PM, Faden AI, Helbok R, Tisherman S, Zanier ER, Valenzuela T, Wendon J, Menon DK, Vincent JL. Neuroprotection in acute brain injury: an up-to-date review. Crit Care. 2015 Apr 21; 19:186. PMID: 25896893.
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    14. Chesnut R, Videtta W, Vespa P, Le Roux P. Intracranial pressure monitoring: fundamental considerations and rationale for monitoring. Neurocrit Care. 2014 Dec; 21 Suppl 2:S64-84. PMID: 25208680.
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    15. Le Roux P, Menon DK, Citerio G, Vespa P, Bader MK, Brophy GM, Diringer MN, Stocchetti N, Videtta W, Armonda R, Badjatia N, B?esel J, Chesnut R, Chou S, Claassen J, Czosnyka M, De Georgia M, Figaji A, Fugate J, Helbok R, Horowitz D, Hutchinson P, Kumar M, McNett M, Miller C, Naidech A, Oddo M, Olson D, O'Phelan K, Provencio JJ, Puppo C, Riker R, Robertson C, Schmidt M, Taccone F. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Neurocrit Care. 2014 Dec; 21 Suppl 2:S1-26. PMID: 25208678.
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    16. Le Roux P, Menon DK, Citerio G, Vespa P, Bader MK, Brophy G, Diringer MN, Stocchetti N, Videtta W, Armonda R, Badjatia N, B?sel J, Chesnut R, Chou S, Claassen J, Czosnyka M, De Georgia M, Figaji A, Fugate J, Helbok R, Horowitz D, Hutchinson P, Kumar M, McNett M, Miller C, Naidech A, Oddo M, Olson D, O'Phelan K, Provencio JJ, Puppo C, Riker R, Roberson C, Schmidt M, Taccone F. The International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: a list of recommendations and additional conclusions: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Neurocrit Care. 2014 Dec; 21 Suppl 2:S282-96. PMID: 25501689.
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    17. Jaja BN, Attalla D, Macdonald RL, Schweizer TA, Cusimano MD, Etminan N, Hanggi D, Hasan D, Johnston SC, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Noble A, Quinn A, Schenk T, Spears J, Singh J, Todd M, Torner J, Tseng M, van den Bergh W, Vergouwen MD, Wong GK. The Subarachnoid Hemorrhage International Trialists (SAHIT) Repository: advancing clinical research in subarachnoid hemorrhage. Neurocrit Care. 2014 Dec; 21(3):551-9. PMID: 24865271.
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    18. Le Roux P, Menon DK, Citerio G, Vespa P, Bader MK, Brophy G, Diringer MN, Stocchetti N, Videtta W, Armonda R, Badjatia N, B?sel J, Chesnut R, Chou S, Claassen J, Czosnyka M, De Georgia M, Figaji A, Fugate J, Helbok R, Horowitz D, Hutchinson P, Kumar M, McNett M, Miller C, Naidech A, Oddo M, Olson D, O'Phelan K, Provencio JJ, Puppo C, Riker R, Roberson C, Schmidt M, Taccone F. The International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: evidentiary tables: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Neurocrit Care. 2014 Dec; 21 Suppl 2:S297-361. PMID: 25608916.
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    19. Vespa P, Menon D, Le Roux P. The International Multi-disciplinary Consensus Conference on Multimodality Monitoring: future directions and emerging technologies. Neurocrit Care. 2014 Dec; 21 Suppl 2:S270-81. PMID: 25208681.
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    20. Helbok R, Olson DM, Le Roux PD, Vespa P. Intracranial pressure and cerebral perfusion pressure monitoring in non-TBI patients: special considerations. Neurocrit Care. 2014 Dec; 21 Suppl 2:S85-94. PMID: 25208677.
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    21. Le Roux P, Menon DK, Citerio G, Vespa P, Bader MK, Brophy GM, Diringer MN, Stocchetti N, Videtta W, Armonda R, Badjatia N, B?esel J, Chesnut R, Chou S, Claassen J, Czosnyka M, De Georgia M, Figaji A, Fugate J, Helbok R, Horowitz D, Hutchinson P, Kumar M, McNett M, Miller C, Naidech A, Oddo M, Olson D, O'Phelan K, Provencio JJ, Puppo C, Riker R, Robertson C, Schmidt M, Taccone F. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care : a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine. Intensive Care Med. 2014 Sep; 40(9):1189-209. PMID: 25138226.
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    22. Le Roux P, Pollack CV, Milan M, Schaefer A. Race against the clock: overcoming challenges in the management of anticoagulant-associated intracerebral hemorrhage. J Neurosurg. 2014 Aug; 121 Suppl:1-20. PMID: 25081496.
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    23. Syre P, Bohman LE, Baltuch G, Le Roux P, Welch WC. Cerebrospinal fluid leaks and their management after anterior cervical discectomy and fusion: a report of 13 cases and a review of the literature. Spine (Phila Pa 1976). 2014 Jul 15; 39(16):E936-43. PMID: 25010015.
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    24. Deschildre A, Pin I, El Abd K, Belmin-Larrar S, El Mourad S, Thumerelle C, Le Roux P, Langlois C, de Blic J. Asthma control assessment in a pediatric population: comparison between GINA/NAEPP guidelines, Childhood Asthma Control Test (C-ACT), and physician's rating. Allergy. 2014 Jun; 69(6):784-90. PMID: 24725204.
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    25. Le Roux P. Intracranial pressure after the BEST TRIP trial: a call for more monitoring. Curr Opin Crit Care. 2014 Apr; 20(2):141-7. PMID: 24584171.
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    26. Le Roux PD, Oddo M. Parenchymal brain oxygen monitoring in the neurocritical care unit. Neurosurg Clin N Am. 2013 Jul; 24(3):427-39. PMID: 23809036.
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    27. Le Roux P. Physiological monitoring of the severe traumatic brain injury patient in the intensive care unit. Curr Neurol Neurosci Rep. 2013 Mar; 13(3):331. PMID: 23328942.
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    28. Jaja BN, Cusimano MD, Etminan N, Hanggi D, Hasan D, Ilodigwe D, Lantigua H, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Quinn A, Schweizer TA, Schenk T, Spears J, Todd M, Torner J, Vergouwen MD, Wong GK, Singh J, Macdonald RL. Clinical prediction models for aneurysmal subarachnoid hemorrhage: a systematic review. Neurocrit Care. 2013 Feb; 18(1):143-53. PMID: 23138544.
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    29. Stocchetti N, Le Roux P, Vespa P, Oddo M, Citerio G, Andrews PJ, Stevens RD, Sharshar T, Taccone FS, Vincent JL. Clinical review: neuromonitoring - an update. Crit Care. 2013 Jan 15; 17(1):201. PMID: 23320763.
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    30. Macdonald RL, Jaja B, Cusimano MD, Etminan N, Hanggi D, Hasan D, Ilodigwe D, Lantigua H, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Quinn A, Schweizer TA, Schenk T, Spears J, Todd M, Torner J, Vergouwen MD, Wong GK, Singh J. SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. Transl Stroke Res. 2013 Jun; 4(3):286-96. PMID: 24323299.
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    31. Macdonald RL, Cusimano MD, Etminan N, Hanggi D, Hasan D, Ilodigwe D, Jaja B, Lantigua H, Le Roux P, Lo B, Louffat-Olivares A, Mayer S, Molyneux A, Quinn A, Schweizer TA, Schenk T, Spears J, Todd M, Torner J, Vergouwen MD, Wong GK. Subarachnoid Hemorrhage International Trialists data repository (SAHIT). World Neurosurg. 2013 Mar-Apr; 79(3-4):418-22. PMID: 23295631.
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    32. Nangunoori R, Maloney-Wilensky E, Stiefel M, Park S, Andrew Kofke W, Levine JM, Yang W, Le Roux PD. Brain tissue oxygen-based therapy and outcome after severe traumatic brain injury: a systematic literature review. Neurocrit Care. 2012 Aug; 17(1):131-8. PMID: 21845489.
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    33. Oddo M, Levine JM, Kumar M, Iglesias K, Frangos S, Maloney-Wilensky E, Le Roux PD. Anemia and brain oxygen after severe traumatic brain injury. Intensive Care Med. 2012 Sep; 38(9):1497-504. PMID: 22584800.
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    34. Katsnelson M, Mackenzie L, Frangos S, Oddo M, Levine JM, Pukenas B, Faerber J, Dong C, Kofke WA, le Roux PD. Are initial radiographic and clinical scales associated with subsequent intracranial pressure and brain oxygen levels after severe traumatic brain injury? Neurosurgery. 2012 May; 70(5):1095-105; discussion 1105. PMID: 22076531.
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    35. Rohlwink UK, Zwane E, Fieggen AG, Argent AC, le Roux PD, Figaji AA. The relationship between intracranial pressure and brain oxygenation in children with severe traumatic brain injury. Neurosurgery. 2012 May; 70(5):1220-30; discussion 1231. PMID: 22134142.
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    36. Kramer AH, Le Roux P. Red Blood Cell Transfusion and Transfusion Alternatives in Traumatic Brain Injury. Curr Treat Options Neurol. 2012 04; 14(2):150-163. PMID: 22314930.
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    37. Le Roux PD, Cooper J, Guntupalli KK, Silbergleit R, Daily J, Geocadin R, Wijman CA, Suarez JI. The critical care research networks experience. Neurocrit Care. 2012 Feb; 16(1):20-8. PMID: 21796493.
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    38. Hall CE, Mirski M, Palesch YY, Diringer MN, Qureshi AI, Robertson CS, Geocadin R, Wijman CA, Le Roux PD, Suarez JI. Clinical trial design in the neurocritical care unit. Neurocrit Care. 2012 Feb; 16(1):6-19. PMID: 21792753.
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    39. Suarez JI, Geocadin R, Hall C, Le Roux PD, Smirnakis S, Wijman CA, Zaidat OO. The neurocritical care research network: NCRN. Neurocrit Care. 2012 Feb; 16(1):29-34. PMID: 21792751.
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    40. Olson DM, McNett MM, Livesay S, Le Roux PD, Suarez JI, Bautista C. Neurocritical care nursing research priorities. Neurocrit Care. 2012 Feb; 16(1):55-62. PMID: 21786045.
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    41. Wijman CA, Smirnakis SM, Vespa P, Szigeti K, Ziai WC, Ning MM, Rosand J, Hanley DF, Geocadin R, Hall C, Le Roux PD, Suarez JI, Zaidat OO. Research and technology in neurocritical care. Neurocrit Care. 2012 Feb; 16(1):42-54. PMID: 21796494.
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    42. Larach DB, Kofke WA, Le Roux P. Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature. Neurocrit Care. 2011 Dec; 15(3):609-22. PMID: 21336786.
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    43. Diringer MN, Bleck TP, Claude Hemphill J, Menon D, Shutter L, Vespa P, Bruder N, Connolly ES, Citerio G, Gress D, H?nggi D, Hoh BL, Lanzino G, Le Roux P, Rabinstein A, Schmutzhard E, Stocchetti N, Suarez JI, Treggiari M, Tseng MY, Vergouwen MD, Wolf S, Zipfel G. Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. Neurocrit Care. 2011 Sep; 15(2):211-40. PMID: 21773873.
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    44. Le Roux PD. Anemia and transfusion after subarachnoid hemorrhage. Neurocrit Care. 2011 Sep; 15(2):342-53. PMID: 21769459.
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    45. Bohman LE, Heuer GG, Macyszyn L, Maloney-Wilensky E, Frangos S, Le Roux PD, Kofke A, Levine JM, Stiefel MF. Medical management of compromised brain oxygen in patients with severe traumatic brain injury. Neurocrit Care. 2011 Jun; 14(3):361-9. PMID: 21394543.
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    46. Kramer AH, Diringer MN, Suarez JI, Naidech AM, Macdonald LR, Le Roux PD. Red blood cell transfusion in patients with subarachnoid hemorrhage: a multidisciplinary North American survey. Crit Care. 2011; 15(1):R30. PMID: 21244675.
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    47. Peace K, Maloney-Wilensky E, Frangos S, Hujcs M, Levine J, Kofke WA, Yang W, Le Roux PD. Portable head CT scan and its effect on intracranial pressure, cerebral perfusion pressure, and brain oxygen. J Neurosurg. 2011 May; 114(5):1479-84. PMID: 21166566.
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    48. Monnerie H, Hsu FC, Coulter DA, Le Roux PD. Role of the NR2A/2B subunits of the N-methyl-D-aspartate receptor in glutamate-induced glutamic acid decarboxylase alteration in cortical GABAergic neurons in vitro. Neuroscience. 2010 Dec 29; 171(4):1075-90. PMID: 20923697.
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    49. Ledwith MB, Bloom S, Maloney-Wilensky E, Coyle B, Polomano RC, Le Roux PD. Effect of body position on cerebral oxygenation and physiologic parameters in patients with acute neurological conditions. J Neurosci Nurs. 2010 Oct; 42(5):280-7. PMID: 20968224.
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    50. Kasner SE, Baren JM, Le Roux PD, Nathanson PG, Lamond K, Rosenberg SL, Karlawish J. Community views on neurologic emergency treatment trials. Ann Emerg Med. 2011 Apr; 57(4):346-354.e6. PMID: 20875693.
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    51. Spiotta AM, Stiefel MF, Gracias VH, Garuffe AM, Kofke WA, Maloney-Wilensky E, Troxel AB, Levine JM, Le Roux PD. Brain tissue oxygen-directed management and outcome in patients with severe traumatic brain injury. J Neurosurg. 2010 Sep; 113(3):571-80. PMID: 20415526.
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    52. Burd I, Bentz AI, Chai J, Gonzalez J, Monnerie H, Le Roux PD, Cohen AS, Yudkoff M, Elovitz MA. Inflammation-induced preterm birth alters neuronal morphology in the mouse fetal brain. J Neurosci Res. 2010 Jul; 88(9):1872-81. PMID: 20155801.
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    53. Magge SN, Chen HI, Ramakrishna R, Cen L, Chen Z, Elliott JP, Winn HR, Le Roux PD. Association of a younger age with an increased risk of angiographic and symptomatic vasospasms following subarachnoid hemorrhage. J Neurosurg. 2010 Jun; 112(6):1208-15. PMID: 19835470.
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    54. Figaji AA, Zwane E, Graham Fieggen A, Argent AC, Le Roux PD, Peter JC. The effect of increased inspired fraction of oxygen on brain tissue oxygen tension in children with severe traumatic brain injury. Neurocrit Care. 2010 Jun; 12(3):430-7. PMID: 20232264.
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    55. Weiner GM, Lacey MR, Mackenzie L, Shah DP, Frangos SG, Grady MS, Kofke A, Levine J, Schuster J, Le Roux PD. Decompressive craniectomy for elevated intracranial pressure and its effect on the cumulative ischemic burden and therapeutic intensity levels after severe traumatic brain injury. Neurosurgery. 2010 Jun; 66(6):1111-8; discussion 1118-9. PMID: 20386136.
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    56. Monnerie H, Tang-Schomer MD, Iwata A, Smith DH, Kim HA, Le Roux PD. Dendritic alterations after dynamic axonal stretch injury in vitro. Exp Neurol. 2010 Aug; 224(2):415-23. PMID: 20478308.
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    57. Figaji AA, Zwane E, Kogels M, Fieggen AG, Argent AC, Le Roux PD, Peter JC. The effect of blood transfusion on brain oxygenation in children with severe traumatic brain injury. Pediatr Crit Care Med. 2010 May; 11(3):325-31. PMID: 19794323.
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    58. Swanson EW, Mascitelli J, Stiefel M, MacMurtrie E, Levine J, Kofke WA, Yang W, Le Roux PD. Patient transport and brain oxygen in comatose patients. Neurosurgery. 2010 May; 66(5):925-31; discussion 931-2. PMID: 20404697.
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    59. Maloney-Wilensky E, Le Roux P. The physiology behind direct brain oxygen monitors and practical aspects of their use. Childs Nerv Syst. 2010 Apr; 26(4):419-30. PMID: 19937246.
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    60. Peace K, Wilensky EM, Frangos S, MacMurtrie E, Shields E, Hujcs M, Levine J, Kofke A, Yang W, Le Roux PD. The use of a portable head CT scanner in the intensive care unit. J Neurosci Nurs. 2010 Apr; 42(2):109-16. PMID: 20422797.
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    61. Oddo M, Frangos S, Maloney-Wilensky E, Andrew Kofke W, Le Roux PD, Levine JM. Effect of shivering on brain tissue oxygenation during induced normothermia in patients with severe brain injury. Neurocrit Care. 2010 Feb; 12(1):10-6. PMID: 19821062.
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    62. Levine J, Kofke A, Cen L, Chen Z, Faerber J, Elliott JP, Winn HR, Le Roux P. Red blood cell transfusion is associated with infection and extracerebral complications after subarachnoid hemorrhage. Neurosurgery. 2010 Feb; 66(2):312-8; discussion 318. PMID: 20042985.
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    63. Figaji AA, Zwane E, Fieggen AG, Argent AC, Le Roux PD, Siesjo P, Peter JC. Pressure autoregulation, intracranial pressure, and brain tissue oxygenation in children with severe traumatic brain injury. J Neurosurg Pediatr. 2009 Nov; 4(5):420-8. PMID: 19877773.
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    64. Burd I, Chai J, Gonzalez J, Ofori E, Monnerie H, Le Roux PD, Elovitz MA. Beyond white matter damage: fetal neuronal injury in a mouse model of preterm birth. Am J Obstet Gynecol. 2009 Sep; 201(3):279.e1-8. PMID: 19733279.
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    65. Del Giudice A, Plaum J, Maloney E, Kasner SE, Le Roux PD, Baren JM. Who will consent to emergency treatment trials for subarachnoid hemorrhage? Acad Emerg Med. 2009 Apr; 16(4):309-15. PMID: 19298620.
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    66. Oddo M, Milby A, Chen I, Frangos S, MacMurtrie E, Maloney-Wilensky E, Stiefel M, Kofke WA, Levine JM, Le Roux PD. Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage. Stroke. 2009 Apr; 40(4):1275-81. PMID: 19265059.
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    67. Ramakrishna R, Stiefel M, Udoetuk J, Spiotta A, Levine JM, Kofke WA, Zager E, Yang W, Le Roux P. Erratum. J Neurosurg. 2009 Mar; 110(3):613. PMID: 28306374.
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    68. Oddo M, Frangos S, Milby A, Chen I, Maloney-Wilensky E, Murtrie EM, Stiefel M, Kofke WA, Le Roux PD, Levine JM. Induced normothermia attenuates cerebral metabolic distress in patients with aneurysmal subarachnoid hemorrhage and refractory Fever. Stroke. 2009 May; 40(5):1913-6. PMID: 19246699.
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    69. Figaji AA, Zwane E, Thompson C, Fieggen AG, Argent AC, Le Roux PD, Peter JC. Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury. Part 1: Relationship with outcome. Childs Nerv Syst. 2009 Oct; 25(10):1325-33. PMID: 19214532.
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    70. Figaji AA, Zwane E, Thompson C, Fieggen AG, Argent AC, Le Roux PD, Peter JC. Brain tissue oxygen tension monitoring in pediatric severe traumatic brain injury. Part 2: Relationship with clinical, physiological, and treatment factors. Childs Nerv Syst. 2009 Oct; 25(10):1335-43. PMID: 19214533.
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    71. Oddo M, Schmidt JM, Carrera E, Badjatia N, Connolly ES, Presciutti M, Ostapkovich ND, Levine JM, Le Roux P, Mayer SA. Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: a microdialysis study. Crit Care Med. 2008 Dec; 36(12):3233-8. PMID: 18936695.
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    72. Figaji AA, Sandler SI, Fieggen AG, Le Roux PD, Peter JC, Argent AC. Continuous monitoring and intervention for cerebral ischemia in tuberculous meningitis. Pediatr Crit Care Med. 2008 Jul; 9(4):e25-30. PMID: 18843248.
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    73. Oddo M, Le Roux P. Brain tissue oxygen monitors: more than an ischemia monitor. Crit Care Med. 2008 Jun; 36(6):1984-5. PMID: 18520668.
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    74. Monnerie H, Le Roux PD. Glutamate alteration of glutamic acid decarboxylase (GAD) in GABAergic neurons: the role of cysteine proteases. Exp Neurol. 2008 Sep; 213(1):145-53. PMID: 18599042.
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    75. Spiotta AM, Stiefel MF, Heuer GG, Bloom S, Maloney-Wilensky E, Yang W, Grady MS, Le Roux PD. Brain hyperthermia after traumatic brain injury does not reduce brain oxygen. Neurosurgery. 2008 Apr; 62(4):864-72; discussion 872. PMID: 18414135.
      Citations:    
    76. Figaji AA, Fieggen AG, Argent AC, Le Roux PD, Peter JC. Intracranial pressure and cerebral oxygenation changes after decompressive craniectomy in children with severe traumatic brain injury. Acta Neurochir Suppl. 2008; 102:77-80. PMID: 19388292.
      Citations:    
    77. Figaji AA, Fieggen AG, Sandler SJ, Argent AC, Le Roux PD, Peter JC. Intracranial pressure and cerebral oxygenation changes after decompressive craniectomy in a child with traumatic brain swelling. Childs Nerv Syst. 2007 Nov; 23(11):1331-5. PMID: 17632729.
      Citations:    
    78. Oner AY, Tali T, Celikyay F, Celik A, Le Roux P. Diffusion-weighted imaging of the spine with a non-carr-purcell-meiboom-gill single-shot fast spin-echo sequence: initial experience. AJNR Am J Neuroradiol. 2007 Mar; 28(3):575-80. PMID: 17353340.
      Citations:    
    79. Monnerie H, Le Roux PD. Reduced dendrite growth and altered glutamic acid decarboxylase (GAD) 65- and 67-kDa isoform protein expression from mouse cortical GABAergic neurons following excitotoxic injury in vitro. Exp Neurol. 2007 Jun; 205(2):367-82. PMID: 17433299.
      Citations:    
    80. Stiefel MF, Udoetuk JD, Spiotta AM, Gracias VH, Goldberg A, Maloney-Wilensky E, Bloom S, Le Roux PD. Conventional neurocritical care and cerebral oxygenation after traumatic brain injury. J Neurosurg. 2006 Oct; 105(4):568-75. PMID: 17044560.
      Citations:    
    81. Monnerie H, Le Roux PD. Glutamate receptor agonist kainate enhances primary dendrite number and length from immature mouse cortical neurons in vitro. J Neurosci Res. 2006 May 01; 83(6):944-56. PMID: 16498632.
      Citations:    
    82. Rabinowitz L, Monnerie H, Shashidhara S, Le Roux PD. Growth of rat cortical neurons on DuraGen, a collagen-based dural graft matrix. Neurol Res. 2005 Dec; 27(8):887-94. PMID: 16354551.
      Citations:    
    83. Monnerie H, Esquenazi S, Shashidhara S, Le Roux PD. Beta-amyloid-induced reactive astrocytes display altered ability to support dendrite and axon growth from mouse cerebral cortical neurons in vitro. Neurol Res. 2005 Jul; 27(5):525-32. PMID: 15978180.
      Citations:    
    84. Smith MJ, Stiefel MF, Magge S, Frangos S, Bloom S, Gracias V, Le Roux PD. Packed red blood cell transfusion increases local cerebral oxygenation. Crit Care Med. 2005 May; 33(5):1104-8. PMID: 15891343.
      Citations:    
    85. Smith ML, Abrahams JM, Chandela S, Smith MJ, Hurst RW, Le Roux PD. Subarachnoid hemorrhage on computed tomography scanning and the development of cerebral vasospasm: the Fisher grade revisited. Surg Neurol. 2005 Mar; 63(3):229-34; discussion 234-5. PMID: 15734507.
      Citations:    
    86. Smith MJ, Le Roux PD, Elliott JP, Winn HR. Blood transfusion and increased risk for vasospasm and poor outcome after subarachnoid hemorrhage. J Neurosurg. 2004 Jul; 101(1):1-7. PMID: 15255244.
      Citations:    
    87. Monnerie H, Shashidhara S, Le Roux PD. Effect of excess extracellular glutamate on dendrite growth from cerebral cortical neurons at 3 days in vitro: Involvement of NMDA receptors. J Neurosci Res. 2003 Dec 01; 74(5):688-700. PMID: 14635220.
      Citations:    
    88. Monnerie H, Shashidhara S, Le Roux PD. Decreased dendrite growth from cultured mouse cortical neurons surviving excitotoxic activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate/kainate receptors. Neurosci Lett. 2003 Jul 24; 345(3):182-6. PMID: 12842286.
      Citations:    
    89. Frempong-Boadu A, Houten JK, Osborn B, Opulencia J, Kells L, Guida DD, Le Roux PD. Swallowing and speech dysfunction in patients undergoing anterior cervical discectomy and fusion: a prospective, objective preoperative and postoperative assessment. J Spinal Disord Tech. 2002 Oct; 15(5):362-8. PMID: 12394659.
      Citations:    
    90. Esquenazi S, Monnerie H, Kaplan P, Le Roux P. BMP-7 and excess glutamate: opposing effects on dendrite growth from cerebral cortical neurons in vitro. Exp Neurol. 2002 Jul; 176(1):41-54. PMID: 12093081.
      Citations:    
    91. Le Roux PD, Elliott JP, Winn HR. Blood transfusion during aneurysm surgery. Neurosurgery. 2001 Nov; 49(5):1068-74; discussion 1074-5. PMID: 11846899.
      Citations:    
    92. Dubus JC, Marguet C, Deschildre A, Mely L, Le Roux P, Brouard J, Huiart L. Local side-effects of inhaled corticosteroids in asthmatic children: influence of drug, dose, age, and device. Allergy. 2001 Oct; 56(10):944-8. PMID: 11576072.
      Citations:    
    93. Le Roux PD, Das H, Esquenazi S, Kelly PJ. Robot-assisted microsurgery: a feasibility study in the rat. Neurosurgery. 2001 Mar; 48(3):584-9. PMID: 11270549.
      Citations:    
    94. Huang PP, Esquenazi S, Le Roux PD. Cerebral cortical neuron apoptosis after mild excitotoxic injury in vitro: different roles of mesencephalic and cortical astrocytes. Neurosurgery. 1999 Dec; 45(6):1413-22. PMID: 10598709.
      Citations:    
    95. Le Roux P, Behar S, Higgins D, Charette M. OP-1 enhances dendritic growth from cerebral cortical neurons in vitro. Exp Neurol. 1999 Nov; 160(1):151-63. PMID: 10630200.
      Citations:    
    96. Le Roux PD, Winn HR. Intracranial aneurysms and subarachnoid hemorrhage management of the poor grade patient. Acta Neurochir Suppl. 1999; 72:7-26. PMID: 10337410.
      Citations:    
    97. Le Roux PD, Samudrala S. Postoperative pain after lumbar disc surgery: a comparison between parenteral ketorolac and narcotics. Acta Neurochir (Wien). 1999; 141(3):261-7. PMID: 10214482.
      Citations:    
    98. Le Roux PD, Winn HR. Surgical approaches to basilar bifurcation aneurysms. Neurosurg Clin N Am. 1998 Oct; 9(4):835-49. PMID: 9738110.
      Citations:    
    99. Elliott JP, Le Roux PD. Subarachnoid hemorrhage and cerebral aneurysms in the elderly. Neurosurg Clin N Am. 1998 Jul; 9(3):587-94. PMID: 9668190.
      Citations:    
    100. Le Roux PD, Winn HR. Management of cerebral aneurysms. How can current management be improved? Neurosurg Clin N Am. 1998 Jul; 9(3):421-33. PMID: 9668177.
      Citations:    
    101. Le Roux PD, Winn HR. Management of the ruptured aneurysm. Neurosurg Clin N Am. 1998 Jul; 9(3):525-40. PMID: 9668184.
      Citations:    
    102. McKhann GM, Le Roux PD. Perioperative and intensive care unit care of patients with aneurysmal subarachnoid hemorrhage. Neurosurg Clin N Am. 1998 Jul; 9(3):595-613. PMID: 9668191.
      Citations:    
    103. Le Roux PD, Elliott JP, Eskridge JM, Cohen W, Winn HR. Risks and benefits of diagnostic angiography after aneurysm surgery: a retrospective analysis of 597 studies. Neurosurgery. 1998 Jun; 42(6):1248-54; discussion 1254-5. PMID: 9632182.
      Citations:    
    104. Elliott JP, Newell DW, Lam DJ, Eskridge JM, Douville CM, Le Roux PD, Lewis DH, Mayberg MR, Grady MS, Winn HR. Comparison of balloon angioplasty and papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg. 1998 Feb; 88(2):277-84. PMID: 9452236.
      Citations:    
    105. Le Roux PD, Newell DW, Lam AM, Grady MS, Winn HR. Cerebral arteriovenous oxygen difference: a predictor of cerebral infarction and outcome in patients with severe head injury. J Neurosurg. 1997 Jul; 87(1):1-8. PMID: 9202258.
      Citations:    
    106. Elliott JP, Le Roux PD, Ransom G, Newell DW, Grady MS, Winn HR. Predicting length of hospital stay and cost by aneurysm grade on admission. J Neurosurg. 1996 Sep; 85(3):388-91. PMID: 8751621.
      Citations:    
    107. Le Roux PD, Elliott JP, Newell DW, Grady MS, Winn HR. Predicting outcome in poor-grade patients with subarachnoid hemorrhage: a retrospective review of 159 aggressively managed cases. J Neurosurg. 1996 Jul; 85(1):39-49. PMID: 8683281.
      Citations:    
    108. Le Roux PD, Elliot JP, Newell DW, Grady MS, Winn HR. The incidence of surgical complications is similar in good and poor grade patients undergoing repair of ruptured anterior circulation aneurysms: a retrospective review of 355 patients. Neurosurgery. 1996 May; 38(5):887-93; discussion 893-5. PMID: 8727813.
      Citations:    
    109. Le Roux PD, Reh TA. Reactive astroglia support primary dendritic but not axonal outgrowth from mouse cortical neurons in vitro. Exp Neurol. 1996 Jan; 137(1):49-65. PMID: 8566212.
      Citations:    
    110. Le Roux PD, Reh TA. Independent regulation of primary dendritic and axonal growth by maturing astrocytes in vitro. Neurosci Lett. 1995 Sep 22; 198(1):5-8. PMID: 8570095.
      Citations:    
    111. Le Roux PD, Elliott JP, Downey L, Newell DW, Grady MS, Mayberg MR, Eskridge JM, Winn HR. Improved outcome after rupture of anterior circulation aneurysms: a retrospective 10-year review of 224 good-grade patients. J Neurosurg. 1995 Sep; 83(3):394-402. PMID: 7666213.
      Citations:    
    112. Le Roux PD, Reh TA. Astroglia demonstrate regional differences in their ability to maintain primary dendritic outgrowth from mouse cortical neurons in vitro. J Neurobiol. 1995 May; 27(1):97-112. PMID: 7643079.
      Citations:    
    113. Le Roux PD, Reh TA. Regional differences in glial-derived factors that promote dendritic outgrowth from mouse cortical neurons in vitro. J Neurosci. 1994 Aug; 14(8):4639-55. PMID: 8046440.
      Citations:    
    114. Le Roux PD, Newell DW, Eskridge J, Mayberg MR, Winn HR. Severe symptomatic vasospasm: the role of immediate postoperative angioplasty. J Neurosurg. 1994 Feb; 80(2):224-9. PMID: 8283260.
      Citations:    
    115. Le Roux PD, Dailey AT, Newell DW, Grady MS, Winn HR. Emergent aneurysm clipping without angiography in the moribund patient with intracerebral hemorrhage: the use of infusion computed tomography scans. Neurosurgery. 1993 Aug; 33(2):189-97; discussion 197. PMID: 8367040.
      Citations:    
    116. Le Roux PD, Haglund MM, Harris AB. Thoracic disc disease: experience with the transpedicular approach in twenty consecutive patients. Neurosurgery. 1993 Jul; 33(1):58-66. PMID: 8355848.
      Citations:    
    117. Le Roux P, Winn HR. Care of patients with aneurysms. West J Med. 1993 Jan; 158(1):70-1. PMID: 8470395.
      Citations:    
    118. Le Roux PD, Berger MS, Wang K, Mack LA, Ojemann GA. Low grade gliomas: comparison of intraoperative ultrasound characteristics with preoperative imaging studies. J Neurooncol. 1992 Jun; 13(2):189-98. PMID: 1432034.
      Citations:    
    119. Le Roux PD, Jardine DS, Kanev PM, Loeser JD. Pediatric intracranial pressure monitoring in hypoxic and nonhypoxic brain injury. Childs Nerv Syst. 1991 Feb; 7(1):34-9. PMID: 2054806.
      Citations:    
    120. Le Roux P, Berger M, Benjamin D. Abdominal x-ray and pathological findings in distal unishunt obstruction. Neurosurgery. 1988 Dec; 23(6):749-52. PMID: 3216973.
      Citations:    
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