Thomas Jefferson University

Julia Barthold

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19023
Phone3026515986
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    R01HD060769     (BARTHOLD, JULIA SPENCER)Jun 27, 2010 - Nov 30, 2015
    NIH
    Genetic Basis of Cryptorchidism
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fwu CW, Schulman IH, Kimmel PL, Eggers P, Norton J, Chan K, Mendley SR, Barthold JS. Reply: Association of Obesity, Metabolic Syndrome, and Diabetes With Urinary Incontinence and Chronic Kidney Disease: Analysis of the National Health and Nutrition Examination Survey, 2003-2020. J Urol. 2024 06; 211(6):801. PMID: 38603593.
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    2. Fwu CW, Schulman IH, Lawrence JM, Kimmel PL, Eggers P, Norton J, Chan K, Mendley SR, Barthold JS. Association of Obesity, Metabolic Syndrome, and Diabetes With Urinary Incontinence and Chronic Kidney Disease: Analysis of the National Health and Nutrition Examination Survey, 2003-2020. J Urol. 2024 01; 211(1):124-133. PMID: 37862455.
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    3. Fwu CW, Barthold JS, Mendley SR, Bennett K, Chan K, Wilkins KJ, Parsa A, Norton JM, Eggers PW, Kimmel PL, Schulman IH, Kirkali Z. Epidemiology of Infantile Ureteropelvic Junction Obstruction in the US. Urology. 2024 01; 183:185-191. PMID: 37802192.
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    4. Morgan JT, Robbins AK, Mateson AB, Sawamoto K, Tomatsu S, Gray DR, Gleghorn JP, Barthold JS. Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat. Front Endocrinol (Lausanne). 2018; 9:738. PMID: 30568634.
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    5. Barthold JS, Ivell R. Perspective: A Neuro-Hormonal Systems Approach to Understanding the Complexity of Cryptorchidism Susceptibility. Front Endocrinol (Lausanne). 2018; 9:401. PMID: 30083133.
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    6. Wang Y, Gray DR, Robbins AK, Crowgey EL, Chanock SJ, Greene MH, McGlynn KA, Nathanson K, Turnbull C, Wang Z, Devoto M, Barthold JS. Subphenotype meta-analysis of testicular cancer genome-wide association study data suggests a role for RBFOX family genes in cryptorchidism susceptibility. Hum Reprod. 2018 05 01; 33(5):967-977. PMID: 29618007.
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    7. Barthold JS, Wintner A, Hagerty JA, Rogers KJ, Hossain MJ. Cryptorchidism in Boys With Cerebral Palsy Is Associated With the Severity of Disease and With Co-Occurrence of Other Congenital Anomalies. Front Endocrinol (Lausanne). 2018; 9:151. PMID: 29713311.
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    8. Wang Y, Li J, Kolon TF, Olivant Fisher A, Figueroa TE, BaniHani AH, Hagerty JA, Gonzalez R, Noh PH, Chiavacci RM, Harden KR, Abrams DJ, Stabley D, Kim CE, Sol-Church K, Hakonarson H, Devoto M, Barthold JS. Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism. BMC Urol. 2016 Oct 21; 16(1):62. PMID: 27769252.
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    9. Barthold JS, Reinhardt S, Thorup J. Genetic, Maternal, and Environmental Risk Factors for Cryptorchidism: An Update. Eur J Pediatr Surg. 2016 Oct; 26(5):399-408. PMID: 27642851.
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    10. Sathyanarayana S, Grady R, Barrett ES, Redmon B, Nguyen RHN, Barthold JS, Bush NR, Swan SH. First trimester phthalate exposure and male newborn genital anomalies. Environ Res. 2016 Nov; 151:777-782. PMID: 27567446.
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    11. Robbins AK, Mateson AB, Khandha A, Pugarelli JE, Buchanan TS, Akins RE, Barthold JS. Fetal Rat Gubernaculum Mesenchymal Cells Adopt Myogenic and Myofibroblast-Like Phenotypes. J Urol. 2016 07; 196(1):270-8. PMID: 26748163.
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    12. Barthold JS, Pugarelli J, MacDonald ML, Ren J, Adetunji MO, Polson SW, Mateson A, Wang Y, Sol-Church K, McCahan SM, Akins RE, Devoto M, Robbins AK. Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat. Mol Hum Reprod. 2016 Jan; 22(1):18-34. PMID: 26502805.
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    13. Barthold JS, Wang Y, Kolon TF, Kollin C, Nordenskj?ld A, Olivant Fisher A, Figueroa TE, BaniHani AH, Hagerty JA, Gonzal?z R, Noh PH, Chiavacci RM, Harden KR, Abrams DJ, Kim CE, Li J, Hakonarson H, Devoto M. Pathway analysis supports association of nonsyndromic cryptorchidism with genetic loci linked to cytoskeleton-dependent functions. Hum Reprod. 2015 Oct; 30(10):2439-51. PMID: 26209787.
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    14. Barthold JS. What regulates neonatal gonocyte migration? J Urol. 2015 Apr; 193(4):1087-8. PMID: 25596357.
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    15. Barthold JS, Wang Y, Kolon TF, Kollin C, Nordenskj?ld A, Olivant Fisher A, Figueroa TE, BaniHani AH, Hagerty JA, Gonzalez R, Noh PH, Chiavacci RM, Harden KR, Abrams DJ, Kim CE, Mateson AB, Robbins AK, Li J, Akins RE, Hakonarson H, Devoto M. Phenotype specific association of the TGFBR3 locus with nonsyndromic cryptorchidism. J Urol. 2015 May; 193(5):1637-45. PMID: 25390077.
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    16. Rodriguez E, Barthold JS, Kreiger PA, Armani MH, Wang J, Michelini KA, Wolfson MR, Boyce R, Barone CA, Zhu Y, Waldman SA, Shaffer TH. The orl rat is more responsive to methacholine challenge than wild type. Pulm Pharmacol Ther. 2014 Dec; 29(2):199-208. PMID: 25218882.
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    17. Barthold JS, Robbins A, Wang Y, Pugarelli J, Mateson A, Anand-Ivell R, Ivell R, McCahan SM, Akins RE. Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling. Biol Reprod. 2014 Aug; 91(2):41. PMID: 24966393.
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    18. Kolon TF, Herndon CD, Baker LA, Baskin LS, Baxter CG, Cheng EY, Diaz M, Lee PA, Seashore CJ, Tasian GE, Barthold JS. Evaluation and treatment of cryptorchidism: AUA guideline. J Urol. 2014 Aug; 192(2):337-45. PMID: 24857650.
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    19. Barthold JS, Wang Y, Robbins A, Pike J, McDowell E, Johnson KJ, McCahan SM. Transcriptome analysis of the dihydrotestosterone-exposed fetal rat gubernaculum identifies common androgen and insulin-like 3 targets. Biol Reprod. 2013 Dec; 89(6):143. PMID: 24174575.
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    20. Barthold JS, Hossain J, Olivant-Fisher A, Reilly A, Figueroa TE, Banihani A, Hagerty J, Gonz?lez R, Noh PH, Manson JM. Altered infant feeding patterns in boys with acquired nonsyndromic cryptorchidism. Birth Defects Res A Clin Mol Teratol. 2012 Nov; 94(11):900-7. PMID: 23081935.
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    21. Barthold JS, Wang Y, Reilly A, Robbins A, Figueroa TE, Banihani A, Hagerty J, Akins RE. Reduced expression of androgen receptor and myosin heavy chain mRNA in cremaster muscle of boys with nonsyndromic cryptorchidism. J Urol. 2012 Oct; 188(4 Suppl):1411-6. PMID: 22906643.
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    22. Barthold JS. Disorders of sex differentiation: a pediatric urologist's perspective of new terminology and recommendations. J Urol. 2011 Feb; 185(2):393-400. PMID: 21167531.
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    23. Johnson KJ, Robbins AK, Wang Y, McCahan SM, Chacko JK, Barthold JS. Insulin-like 3 exposure of the fetal rat gubernaculum modulates expression of genes involved in neural pathways. Biol Reprod. 2010 Nov; 83(5):774-82. PMID: 20631401.
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    24. Ashley RA, Barthold JS, Kolon TF. Cryptorchidism: pathogenesis, diagnosis, treatment and prognosis. Urol Clin North Am. 2010 May; 37(2):183-93. PMID: 20569797.
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    25. Chacko JK, Barthold JS. Genetic and environmental contributors to cryptorchidism. Pediatr Endocrinol Rev. 2009 Jun; 6(4):476-80. PMID: 19550382.
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    26. Johnson KJ, McCahan SM, Si X, Campion L, Herrmann R, Barthold JS. The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure. Toxicol Sci. 2008 Oct; 105(2):360-7. PMID: 18621746.
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    27. Barthold JS. Undescended testis: current theories of etiology. Curr Opin Urol. 2008 Jul; 18(4):395-400. PMID: 18520761.
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    28. Wang Y, Barthold J, Figueroa E, Gonz?lez R, Noh PH, Wang M, Manson J. Analysis of five single nucleotide polymorphisms in the ESR1 gene in cryptorchidism. Birth Defects Res A Clin Mol Teratol. 2008 Jun; 82(6):482-5. PMID: 18452179.
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    29. Chacko JK, Noh PS, Barthold JS, Figueroa TE, Gonzalez R. Iatrogenic ureteral injury after laparoscopic cholecystectomy in a 13-year-old boy. J Pediatr Urol. 2008 Aug; 4(4):322-4. PMID: 18644541.
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    30. Barthold JS, McCahan SM, Singh AV, Knudsen TB, Si X, Campion L, Akins RE. Altered expression of muscle- and cytoskeleton-related genes in a rat strain with inherited cryptorchidism. J Androl. 2008 May-Jun; 29(3):352-66. PMID: 18222913.
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    31. Piaggio LA, Franc-Guimond J, Noh PH, Wehry M, Figueroa TE, Barthold J, Gonz?lez R. Transperitoneal laparoscopic pyeloplasty for primary repair of ureteropelvic junction obstruction in infants and children: comparison with open surgery. J Urol. 2007 Oct; 178(4 Pt 2):1579-83. PMID: 17707047.
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    32. Wang Y, Barthold J, Kanetsky PA, Casalunovo T, Pearson E, Manson J. Allelic variants in HOX genes in cryptorchidism. Birth Defects Res A Clin Mol Teratol. 2007 Apr; 79(4):269-75. PMID: 17216618.
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    33. Barthold JS, Si X, Stabley D, Sol-Church K, Campion L, McCahan SM. Failure of shortening and inversion of the perinatal gubernaculum in the cryptorchid long-evans orl rat. J Urol. 2006 Oct; 176(4 Pt 1):1612-7. PMID: 16952701.
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    34. Piaggio L, Myers S, Figueroa TE, Barthold JS, Gonz?lez R. Influence of type of conduit and site of implantation on the outcome of continent catheterizable channels. J Pediatr Urol. 2007 Jun; 3(3):230-4. PMID: 18947741.
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    35. Piaggio L, Franc-Guimond J, Figueroa TE, Barthold JS, Gonz?lez R. Comparison of laparoscopic and open partial nephrectomy for duplication anomalies in children. J Urol. 2006 Jun; 175(6):2269-73. PMID: 16697852.
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    36. Barthold JS, Manson J, Regan V, Si X, Hassink SG, Coughlin MT, Lee PA. Reproductive hormone levels in infants with cryptorchidism during postnatal activation of the pituitary-testicular axis. J Urol. 2004 Oct; 172(4 Pt 2):1736-41; discussion 1741. PMID: 15371802.
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    37. Barthold JS, Gonz?lez R. The epidemiology of congenital cryptorchidism, testicular ascent and orchiopexy. J Urol. 2003 Dec; 170(6 Pt 1):2396-401. PMID: 14634436.
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    38. Barroso U, Jednak R, Barthold JS, Gonz?lez R. Outcome of ureteral reimplantation in children with the urge syndrome. J Urol. 2001 Sep; 166(3):1031-5. PMID: 11490291.
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    39. Gonz?lez R, De Filippo R, Jednak R, Barthold JS. Urethral atresia: long-term outcome in 6 children who survived the neonatal period. J Urol. 2001 Jun; 165(6 Pt 2):2241-4. PMID: 11371953.
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    40. Barroso U, Jednak R, Barthold JS, Gonz?lez R. A technique for constructing an umbilicus and a concealed catheterizable stoma. BJU Int. 2001 Jan; 87(1):117-20. PMID: 11122004.
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    41. Jednak R, Schimke CM, Barroso U JR, Barthold JS, Gonz?lez R. Further experience with seromuscular colocystoplasty lined with urothelium. J Urol. 2000 Dec; 164(6):2045-9. PMID: 11061922.
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    42. Jednak R, Kryger JV, Barthold JS, Gonz?lez R. A simplified technique of upper pole heminephrectomy for duplex kidney. J Urol. 2000 Oct; 164(4):1326-8. PMID: 10992406.
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    43. Coplen DE, Barthold JS. Controversies in the management of ectopic ureteroceles. Urology. 2000 Oct 01; 56(4):665-8. PMID: 11018629.
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    44. Barthold JS, Kumasi-Rivers K, Upadhyay J, Shekarriz B, Imperato-Mcginley J. Testicular position in the androgen insensitivity syndrome: implications for the role of androgens in testicular descent. J Urol. 2000 Aug; 164(2):497-501. PMID: 10893634.
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    45. De Filippo RE, Barthold JS, Gonz?lez R. The application of magnetic resonance imaging for the preoperative localization of nonpalpable testis in obese children: an alternative to laparoscopy. J Urol. 2000 Jul; 164(1):154-5. PMID: 10840451.
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    46. Barroso U, Jednak R, Fleming P, Barthold JS, Gonz?lez R. Bladder calculi in children who perform clean intermittent catheterization. BJU Int. 2000 May; 85(7):879-84. PMID: 10792170.
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    47. Kryger JV, Gonz?lez R, Barthold JS. Surgical management of urinary incontinence in children with neurogenic sphincteric incompetence. J Urol. 2000 Jan; 163(1):256-63. PMID: 10604371.
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    48. Shekarriz B, Upadhyay J, Demirbilek S, Barthold JS, Gonz?lez R. Surgical complications of bladder augmentation: comparison between various enterocystoplasties in 133 patients. Urology. 2000 Jan; 55(1):123-8. PMID: 10654908.
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    49. Upadhyay J, Shekarriz B, Fleming P, Gonz?lez R, Barthold JS. Ureteral reimplantation in infancy: evaluation of long-term voiding function. J Urol. 1999 Sep; 162(3 Pt 2):1209-12. PMID: 10458468.
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    50. Shekarriz B, Upadhyay J, Fleming P, Gonz?lez R, Barthold JS. Long-term outcome based on the initial surgical approach to ureterocele. J Urol. 1999 Sep; 162(3 Pt 2):1072-6. PMID: 10458434.
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    51. Barthold JS, Martin-Crespo R, Kryger JV, Gonzalez R. Quantitative nuclear cystography does not predict outcome in patients with primary vesicoureteral reflux. J Urol. 1999 Sep; 162(3 Pt 2):1193-6. PMID: 10458464.
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    52. Barthold JS, Kryger JV, Derusha AM, Duel BP, Jednak R, Skafar DF. Effects of an environmental endocrine disruptor on fetal development, estrogen receptor(alpha) and epidermal growth factor receptor expression in the porcine male genital tract. J Urol. 1999 Sep; 162(3 Pt 1):864-71. PMID: 10458397.
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    53. Shekarriz B, Upadhyay J, Freedman AL, Fleming P, Barthold JS, Gonz?lez R. Lack of morbidity from urodynamic studies in children with asymptomatic bacteriuria. Urology. 1999 Aug; 54(2):359-61; discussion 362. PMID: 10443739.
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    54. Duel BP, Vates TS, Heiser D, Barthold JS, Gonz?lez R. Antegrade pyelography before pyeloplasty via dorsal lumbar incision. J Urol. 1999 Jul; 162(1):174-6. PMID: 10379782.
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    55. Vates TS, Fleming P, Leleszi JP, Barthold JS, Gonz?lez R, Perlmutter AD. Functional, social and psychosexual adjustment after vaginal reconstruction. J Urol. 1999 Jul; 162(1):182-7. PMID: 10379784.
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    56. Barthold JS, Rodriguez E, Freedman AL, Fleming PA, Gonz?lez R. Results of the rectus fascial sling and wrap procedures for the treatment of neurogenic sphincteric incontinence. J Urol. 1999 Jan; 161(1):272-4. PMID: 10037423.
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    57. Barroso U, Duel B, Barthold JS, Gonz?lez R. Orthotopic urethral substitution in female patients using the mitrofanoff principle. J Urol. 1999 Jan; 161(1):251-3. PMID: 10037417.
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    58. Barthold JS. Re: Testicular descent: a proposed interaction between m?llerian inhibiting substance and epidermal growth factor. J Urol. 1998 Oct; 160(4):1438-40. PMID: 9751382.
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    59. Duel BP, Mogbo K, Barthold JS, Gonzalez R. Prognostic value of initial renal ultrasound in patients with posterior urethral valves. J Urol. 1998 Sep; 160(3 Pt 2):1198-200; discussion 1216. PMID: 9719309.
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    60. Shekarriz B, Upadhyay J, Barthold JS, Gonzalez R. Infected caliceal diverticulum in a horseshoe kidney. J Urol. 1998 Sep; 160(3 Pt 1):842-3. PMID: 9720571.
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    61. Duel BP, Barthold JS, Gonzalez R. Management of urethral strictures after hypospadias repair. J Urol. 1998 Jul; 160(1):170-1. PMID: 9628643.
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    62. Duel BP, Gonzalez R, Barthold JS. Alternative techniques for augmentation cystoplasty. J Urol. 1998 Mar; 159(3):998-1005. PMID: 9474216.
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    63. Barthold JS. Individualized approach to the prenatally diagnosed ureterocele. J Urol. 1998 Mar; 159(3):1011-2. PMID: 9474219.
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    64. Gheiler EL, Barthold JS, Gonz?lez R. Benefits of laparoscopy and the Jones technique for the nonpalpable testis. J Urol. 1997 Nov; 158(5):1948-51. PMID: 9334646.
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    65. Denes ED, Barthold JS, Gonz?lez R. Early prognostic value of serum creatinine levels in children with posterior urethral valves. J Urol. 1997 Apr; 157(4):1441-3. PMID: 9120976.
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    66. Barthold JS, Redman JF. Association of epididymal anomalies with patent processus vaginalis in hernia, hydrocele and cryptorchidism. J Urol. 1996 Dec; 156(6):2054-6. PMID: 8911389.
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    67. Barthold JS, Mahler HR, Sziszak TJ, Newton BW. Lack of feminization of the cremaster nucleus by prenatal flutamide administration in the rat and pig. J Urol. 1996 Aug; 156(2 Pt 2):767-71. PMID: 8683779.
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    68. Barthold JS, Teer TL, Redman JF. Modified Barcat balanic groove technique for hypospadias repair: experience with 295 cases. J Urol. 1996 May; 155(5):1735-7. PMID: 8627874.
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    69. Redman JF, Barthold JS. Experience with ileal augmentation cystoplasty using a short pfannenstiel incision. J Urol. 1996 May; 155(5):1726-7. PMID: 8627871.
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    70. Redman JF, Barthold JS. A technique for atraumatic scrotal pouch orchiopexy in the management of testicular torsion. J Urol. 1995 Oct; 154(4):1511-2. PMID: 7658580.
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    71. Barthold JS, Mahler HR, Newton BW. Lack of feminization of the cremaster nucleus in cryptorchid androgen insensitive rats. J Urol. 1994 Dec; 152(6 Pt 2):2280-6. PMID: 7966725.
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