Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.
Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation. Biochemistry. 2000 Nov 14; 39(45):13916-24.
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3T3 Cells
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Animals
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Antiviral Agents
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Carcinoma, Squamous Cell
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Caveolin 1
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Caveolins
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Cell Line, Transformed
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Cell Transformation, Neoplastic
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Cell Transformation, Viral
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Down-Regulation
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Female
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Gene Expression Regulation, Neoplastic
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Genes, p53
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Growth Inhibitors
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HeLa Cells
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Humans
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Mice
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Mice, Inbred BALB C
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Oncogene Proteins, Viral
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Papillomaviridae
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Phenotype
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Promoter Regions, Genetic
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Recombinant Proteins
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Repressor Proteins
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Transfection
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Tumor Cells, Cultured
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Tumor Suppressor Protein p53
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Up-Regulation
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Uterine Cervical Neoplasms