"Calcimycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
| Descriptor ID |
D000001
|
| MeSH Number(s) |
D03.633.100.221.173
|
| Concept/Terms |
A-23187- A-23187
- A 23187
- A23187
- Antibiotic A23187
- A23187, Antibiotic
|
Below are MeSH descriptors whose meaning is more general than "Calcimycin".
Below are MeSH descriptors whose meaning is more specific than "Calcimycin".
This graph shows the total number of publications written about "Calcimycin" by people in this website by year, and whether "Calcimycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calcimycin" by people in Profiles.
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Esbert M, Carmody A, Ballesteros A, Seli E, Scott RT. Calcium Ionophore A23187 treatment to rescue unfertilized oocytes: a prospective randomized analysis of sibling oocytes. Reprod Biomed Online. 2022 11; 45(5):878-883.
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Loza MJ, Foster S, Peters SP, Penn RB. Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells. Blood. 2006 Mar 01; 107(5):2052-60.
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Loza MJ, Peters SP, Zangrilli JG, Perussia B. Distinction between IL-13+ and IFN-gamma+ natural killer cells and regulation of their pool size by IL-4. Eur J Immunol. 2002 02; 32(2):413-23.
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Mio M, Kirino Y, Kamei C. Desensitization of beta2-adrenoceptor and hypersensitization to phosphodiesterase inhibitors elicited by beta2-agonists in guinea pig eosinophils. J Allergy Clin Immunol. 2000 Nov; 106(5):896-903.
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Boehning D, Joseph SK. Functional properties of recombinant type I and type III inositol 1, 4,5-trisphosphate receptor isoforms expressed in COS-7 cells. J Biol Chem. 2000 Jul 14; 275(28):21492-9.
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Lopez BL, Snyder JW, Birenbaum DS, Ma XI. N-acetylcysteine enhances endothelium-dependent vasorelaxation in the isolated rat mesenteric artery. Ann Emerg Med. 1998 Oct; 32(4):405-10.
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Simbula G, Glascott PA, Akita S, Hoek JB, Farber JL. Two mechanisms by which ATP depletion potentiates induction of the mitochondrial permeability transition. Am J Physiol. 1997 Aug; 273(2 Pt 1):C479-88.
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Wigle DA, Campling BG, Sarda IR, Shin SH, Watson JD, Frater Y, Flynn TG, Pang SC. ANP secretion from small cell lung cancer cell lines: a potential model of ANP release. Am J Physiol. 1995 May; 268(5 Pt 2):H1869-74.
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Wright SW, Harris RR, Collins RJ, Corbett RL, Green AM, Wadman EA, Batt DG. Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity. J Med Chem. 1992 Aug 21; 35(17):3148-55.
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Kligman I, Glassner M, Storey BT, Kopf GS. Zona pellucida-mediated acrosomal exocytosis in mouse spermatozoa: characterization of an intermediate stage prior to the completion of the acrosome reaction. Dev Biol. 1991 Jun; 145(2):344-55.