Acetylcysteine

"Acetylcysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.

Descriptor ID	D000111
MeSH Number(s)	D02.886.030.230.259 D12.125.166.230.259
Concept/Terms	Acetylcysteine Acetylcysteine N-Acetyl-L-cysteine N Acetyl L cysteine N-Acetylcysteine N Acetylcysteine Mercapturic Acid Acid, Mercapturic Solmucol Solmucol Genac Acemuc Acemuc Acetabs Acetabs Acetylcystein AL Acetylcystein AL NAC AL Acetylcystein Atid Acetylcystein Atid Acetylcystein Heumann Acetylcystein Heumann Acetylcystein Trom Acetylcystein Trom Acetylcysteine Hydrochloride Acetylcysteine Hydrochloride Hydrochloride, Acetylcysteine Acetylcysteine Sodium Acetylcysteine Sodium Sodium, Acetylcysteine Acetylcysteine, Monosodium Salt Monosodium Salt Acetylcysteine Acetylcysteine Zinc Acetylcysteine Zinc Zinc, Acetylcysteine Acetylcysteine, (D)-Isomer Acetylcysteine, (D)-Isomer Acetylcysteine, (DL)-Isomer Acetylcysteine, (DL)-Isomer Acetylcysteine, Monoammonium Salt Acetylcysteine, Monoammonium Salt Monoammonium Salt Acetylcysteine Acetyst Acetyst Acétylcystéine GNR Acétylcystéine GNR Airbron Airbron Alveolex Alveolex Bromuc Azubronchin Azubronchin Bisolvon NAC Bisolvon NAC NAC, Bisolvon Broncho-Fips Broncho-Fips Broncho Fips BronchoFips Broncholysin Broncholysin Broncoclar Broncoclar Codotussyl Codotussyl Cystamucil Cystamucil Dampo Mucopect Dampo Mucopect Mucopect, Dampo durabronchal durabronchal Larylin NAC Eurespiran Eurespiran Exomuc Exomuc Fluimucil Fluimucil NAC Zambon Zambon, NAC Fabrol Fabrol Fluprowit Fluprowit Optipect Hustengetränk Hustengetränk, Optipect Muco Sanigen Sanigen, Muco Frekatuss Frekatuss Jenacystein Jenacystein Jenapharm Lantamed Lantamed Lindocetyl Lindocetyl M-Pectil M-Pectil M Pectil MPectil mentopin Acetylcystein mentopin Acetylcystein Acetylcystein, mentopin Muciteran Muciteran Mucomyst Mucomyst Acetylin Mucosil Mucosil Mucosol Mucosolvin Mucosolvin Siccoral Siccoral Siran Ilube Ilube Hoestil Hoestil acebraus acebraus

Below are MeSH descriptors whose meaning is more general than "Acetylcysteine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Amino Acids, Sulfur [D02.886.030]
Cysteine [D02.886.030.230]
Acetylcysteine [D02.886.030.230.259]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Sulfur [D12.125.166]
Cysteine [D12.125.166.230]
Acetylcysteine [D12.125.166.230.259]

Below are MeSH descriptors whose meaning is related to "Acetylcysteine".

Below are MeSH descriptors whose meaning is more specific than "Acetylcysteine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Acetylcysteine" by people in this website by year, and whether "Acetylcysteine" was a major or minor topic of these publications.

Bar chart showing 38 publications over 21 distinct years, with a maximum of 4 publications in 2002 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	1	0	1
2001	1	0	1
2002	3	1	4
2003	0	1	1
2004	0	1	1
2005	0	1	1
2006	0	2	2
2007	0	1	1
2010	1	3	4
2011	0	1	1
2012	0	2	2
2013	0	1	1
2014	0	3	3
2016	2	0	2
2017	1	1	2
2018	1	1	2
2019	2	1	3
2020	1	0	1
2022	0	1	1
2024	3	0	3

Below are the most recent publications written about "Acetylcysteine" by people in Profiles.

Monti DA, Faezeh V, Zabrecky G, Alizadeh M, Wintering N, Bazzan AJ, Mohamed FB, Newberg AB. Changes in Resting-State Functional Connectivity and Cognitive-Affective Symptoms in Patients With Post-Concussion Syndrome Treated With N-Acetyl Cysteine. J Head Trauma Rehabil. 2025 May-Jun 01; 40(3):E196-E207.

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Quintanilla ME, Morales P, Santapau D, Gallardo J, Rebolledo R, Riveras G, Acu?a T, Herrera-Marschitz M, Israel Y, Ezquer F. Morphine self-administration is inhibited by the antioxidant N-acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration. PLoS One. 2024; 19(10):e0312828.

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Babu Balagopal P, Kohli R, Uppal V, Averill L, Shah C, McGoogan K, Di Guglielmo M, Goran M, Hossain MJ. Effect of N-acetyl cysteine in children with metabolic dysfunction-associated steatotic liver disease-A pilot study. J Pediatr Gastroenterol Nutr. 2024 09; 79(3):652-660.

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Ezquer F, Quintanilla ME, Morales P, Santapau D, Munita JM, Moya-Flores F, Ezquer M, Herrera-Marschitz M, Israel Y. A dual treatment blocks alcohol binge-drinking relapse: Microbiota as a new player. Drug Alcohol Depend. 2022 07 01; 236:109466.

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Sukhonthamarn K, Cho J, Chisari E, Goswami K, Arnold WV, Parvizi J. N-acetylcysteine use as an adjuvant to bone cement to fight periprosthetic joint infections: A preliminary in vitro efficacy and biocompatibility study. J Orthop Res. 2021 02; 39(2):356-364.

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Monti DA, Newberg AB. Response to "Potential Role of N-Acetyl Cysteine in the Cysteine Proteome in Parkinson's Disease?" Clin Pharmacol Ther. 2020 05; 107(5):1056.

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Israel Y, Quintanilla ME, Ezquer F, Morales P, Santapau D, Berr?os-C?rcamo P, Ezquer M, Olivares B, Herrera-Marschitz M. Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation. Addict Biol. 2021 01; 26(1):e12853.

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Monti DA, Zabrecky G, Kremens D, Liang TW, Wintering NA, Bazzan AJ, Zhong L, Bowens BK, Chervoneva I, Intenzo C, Newberg AB. N-Acetyl Cysteine Is Associated With Dopaminergic Improvement in Parkinson's Disease. Clin Pharmacol Ther. 2019 10; 106(4):884-890.

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Quintanilla ME, Morales P, Ezquer F, Ezquer M, Herrera-Marschitz M, Israel Y. Commonality of Ethanol and Nicotine Reinforcement and Relapse in Wistar-Derived UChB Rats: Inhibition by N-Acetylcysteine. Alcohol Clin Exp Res. 2018 10; 42(10):1988-1999.

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Khan AA, Boyle AJ. Letter by Khan and Boyle Regarding Article, "Early Use of N-Acetylcysteine (NAC) With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct Size (The NACIAM Trial [N-Acetylcysteine in Acute Myocardial Infarction])". Circulation. 2018 03 27; 137(13):1418-1419.

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