Amino Acid Chloromethyl Ketones
"Amino Acid Chloromethyl Ketones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
| Descriptor ID |
D000590
|
| MeSH Number(s) |
D12.125.065
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Amino Acid Chloromethyl Ketones".
Below are MeSH descriptors whose meaning is more specific than "Amino Acid Chloromethyl Ketones".
This graph shows the total number of publications written about "Amino Acid Chloromethyl Ketones" by people in this website by year, and whether "Amino Acid Chloromethyl Ketones" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amino Acid Chloromethyl Ketones" by people in Profiles.
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Bassi DE, Zhang J, Cenna J, Litwin S, Cukierman E, Klein-Szanto AJ. Proprotein convertase inhibition results in decreased skin cell proliferation, tumorigenesis, and metastasis. Neoplasia. 2010 Jul; 12(7):516-26.
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Orbach A, Rachmilewitz J, Parnas M, Huang JH, Tykocinski ML, Dranitzki-Elhalel M. CTLA-4 . FasL induces early apoptosis of activated T cells by interfering with anti-apoptotic signals. J Immunol. 2007 Dec 1; 179(11):7287-94.
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Karpinich NO, Tafani M, Schneider T, Russo MA, Farber JL. The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax. J Cell Physiol. 2006 Jul; 208(1):55-63.
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Zeuner A, Eramo A, Testa U, Felli N, Pelosi E, Mariani G, Srinivasula SM, Alnemri ES, Condorelli G, Peschle C, De Maria R. Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1. Cell Death Differ. 2003 Aug; 10(8):905-13.
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Worgall S, Martushova K, Busch A, Lande L, Crystal RG. Apoptosis induced by Pseudomonas aeruginosa in antigen presenting cells is diminished by genetic modification with CD40 ligand. Pediatr Res. 2002 Nov; 52(5):636-44.
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Yang H, Miller WM, Papoutsakis ET. Higher pH promotes megakaryocytic maturation and apoptosis. Stem Cells. 2002; 20(4):320-8.
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Annis MG, Zamzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW. Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event. Oncogene. 2001 Apr 12; 20(16):1939-52.
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Elliott K, Ge K, Du W, Prendergast GC. The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program. Oncogene. 2000 Sep 28; 19(41):4669-84.
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Moran J, Itoh T, Reddy UR, Chen M, Alnemri ES, Pleasure D. Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP. J Neurochem. 1999 Aug; 73(2):568-77.
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Waterhouse NJ, Finucane DM, Green DR, Elce JS, Kumar S, Alnemri ES, Litwack G, Khanna K, Lavin MF, Watters DJ. Calpain activation is upstream of caspases in radiation-induced apoptosis. Cell Death Differ. 1998 Dec; 5(12):1051-61.