Blood-Brain Barrier

"Blood-Brain Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.

Descriptor ID	D001812
MeSH Number(s)	A07.035 A08.186.211.035
Concept/Terms	Blood-Brain Barrier Blood-Brain Barrier Barrier, Blood-Brain Barriers, Blood-Brain Blood Brain Barrier Blood-Brain Barriers Hemato-Encephalic Barrier Barrier, Hemato-Encephalic Barriers, Hemato-Encephalic Hemato Encephalic Barrier Hemato-Encephalic Barriers Brain-Blood Barrier Barrier, Brain-Blood Barriers, Brain-Blood Brain Blood Barrier Brain-Blood Barriers

Below are MeSH descriptors whose meaning is more general than "Blood-Brain Barrier".

Anatomy [A]
Cardiovascular System [A07]
Blood-Brain Barrier [A07.035]
Nervous System [A08]
Central Nervous System [A08.186]
Brain [A08.186.211]
Blood-Brain Barrier [A08.186.211.035]

Below are MeSH descriptors whose meaning is related to "Blood-Brain Barrier".

Below are MeSH descriptors whose meaning is more specific than "Blood-Brain Barrier".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Blood-Brain Barrier" by people in this website by year, and whether "Blood-Brain Barrier" was a major or minor topic of these publications.

Bar chart showing 68 publications over 22 distinct years, with a maximum of 7 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	2	2	4
2001	1	2	3
2002	1	1	2
2004	1	1	2
2006	2	1	3
2007	4	0	4
2008	3	2	5
2009	0	1	1
2010	2	1	3
2011	0	2	2
2012	4	0	4
2013	2	0	2
2014	2	1	3
2015	1	3	4
2016	1	1	2
2017	2	2	4
2018	3	2	5
2019	3	4	7
2021	0	1	1
2023	2	1	3
2024	2	1	3
2025	0	1	1

Below are the most recent publications written about "Blood-Brain Barrier" by people in Profiles.

Diamandi J, Raimondo C, Piper K, Roy J, Serva S, Alizadeh M, Flanders A, Tjoumakaris S, Gooch R, Jabbour P, Rosenwasser R, Mouchtouris N. Use of multi-modal non-contrast MRI to predict functional outcomes after stroke: A study using DP-pCASL, DTI, NODDI, and MAP MRI. Neuroimage Clin. 2025; 45:103742.

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Mouchtouris N, Ailes I, Chang K, Flanders A, Mohamed F, Tjoumakaris S, Gooch R, Jabbour P, Rosenwasser R, Alizadeh M. The impact of mechanical thrombectomy on the blood-brain barrier in patients with acute ischemic stroke: A non-contrast MR imaging study using DP-pCASL and NODDI. Neuroimage Clin. 2024; 43:103629.

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Arag?n-Gonz?lez A, Shaw AC, Kok JR, Roussel FS, Santos Souza CD, Granger SM, Vetter T, de Diego Y, Meyer KC, Beal SN, Shaw PJ, Ferraiuolo L. C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicity. Fluids Barriers CNS. 2024 Apr 11; 21(1):34.

View in: PubMed
Mouchtouris N, Ailes I, Gooch R, Raimondo C, Oghli YS, Tjoumakaris S, Jabbour P, Rosenwasser R, Alizadeh M. Quantifying blood-brain barrier permeability in patients with ischemic stroke using non-contrast MRI. Magn Reson Imaging. 2024 06; 109:165-172.

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Leal AF, Inci OK, Seyrantepe V, Rintz E, Celik B, Ago Y, Le?n D, Suarez DA, Alm?ciga-D?az CJ, Tomatsu S. Molecular Trojan Horses for treating lysosomal storage diseases. Mol Genet Metab. 2023 11; 140(3):107648.

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Chaganti J, Zeng G, Tun N, Lockart I, Abdelshaheed C, Cysique L, Montagnese S, Brew BJ, Danta M. Novel magnetic resonance KTRANS measurement of blood-brain barrier permeability correlated with covert HE. Hepatol Commun. 2023 04 01; 7(4).

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Cecen B, Saygili E, Zare I, Nejati O, Khorsandi D, Zarepour A, Alarcin E, Zarrabi A, Topkaya SN, Yesil-Celiktas O, Mostafavi E, Bal-?zt?rk A. Biosensor integrated brain-on-a-chip platforms: Progress and prospects in clinical translation. Biosens Bioelectron. 2023 Apr 01; 225:115100.

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Chen-Roetling J, Li Y, Cao Y, Yan Z, Lu X, Regan RF. Effect of hemopexin treatment on outcome after intracerebral hemorrhage in mice. Brain Res. 2021 08 15; 1765:147507.

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Chaganti J, Marripudi K, Staub LP, Rae CD, Gates TM, Moffat KJ, Brew BJ. Imaging correlates of the blood-brain barrier disruption in HIV-associated neurocognitive disorder and therapeutic implications. AIDS. 2019 10 01; 33(12):1843-1852.

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Chen HH, Sawamoto K, Mason RW, Kobayashi H, Yamaguchi S, Suzuki Y, Orii K, Orii T, Tomatsu S. Enzyme replacement therapy for mucopolysaccharidoses; past, present, and future. J Hum Genet. 2019 Nov; 64(11):1153-1171.

View in: PubMed

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