Brain Death

"Brain Death" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)

Descriptor ID	D001926
MeSH Number(s)	C10.228.140.151 C10.597.606.358.800.200.100 C23.550.260.159
Concept/Terms	Brain Death Brain Death Death, Brain Brain Dead Brain Deads Coma Depasse Irreversible Coma Irreversible Coma Coma, Irreversible

Below are MeSH descriptors whose meaning is more general than "Brain Death".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Brain Death [C10.228.140.151]
Neurologic Manifestations [C10.597]
Neurobehavioral Manifestations [C10.597.606]
Consciousness Disorders [C10.597.606.358]
Unconsciousness [C10.597.606.358.800]
Coma [C10.597.606.358.800.200]
Brain Death [C10.597.606.358.800.200.100]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Death [C23.550.260]
Brain Death [C23.550.260.159]

Below are MeSH descriptors whose meaning is related to "Brain Death".

Below are MeSH descriptors whose meaning is more specific than "Brain Death".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Brain Death" by people in this website by year, and whether "Brain Death" was a major or minor topic of these publications.

Bar chart showing 14 publications over 12 distinct years, with a maximum of 2 publications in 2021 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2003	0	1	1
2004	0	1	1
2005	0	1	1
2008	1	0	1
2010	0	1	1
2013	0	1	1
2017	0	1	1
2018	0	1	1
2020	0	1	1
2021	1	1	2
2024	1	1	2

Below are the most recent publications written about "Brain Death" by people in Profiles.

Entwistle JW, Sade RM. Change the Law to Optimize Organ Donation. Am J Bioeth. 2024 Jun; 24(6):76-79.

View in: PubMed
Greer DM, Lewis A, Kirschen MP, Rae-Grant A, Halperin JJ. Author Response: Pediatric and Adult Brain Death/Death by Neurologic Criteria Consensus Guideline: Report of the AAN Guidelines Subcommittee, AAP, CNS, and SCCM. Neurology. 2024 May 14; 102(9):e209368.

View in: PubMed
Molnar MZ, Hall IE, Raghavan D, Shihab F, Imlay H, Hanson KE, Gomez CA, Campsen J, Kim R, Baker N, Rofaiel G. Kidney transplantation from SARS-CoV-2-positive deceased donor. Am J Transplant. 2022 04; 22(4):1280-1282.

View in: PubMed
Dodaro MG, Seidenari A, Marino IR, Berghella V, Bellussi F. Brain death in pregnancy: a systematic review focusing on perinatal outcomes. Am J Obstet Gynecol. 2021 05; 224(5):445-469.

View in: PubMed
Zimpfer D, Alexander PMA, Davies RR, Dipchand AI, Feingold B, Joong A, Lord K, Kirk R, Scales A, Shih R, Miera O. Pediatric donor management to optimize donor heart utilization. Pediatr Transplant. 2020 05; 24(3):e13679.

View in: PubMed
Du Pont-Thibodeau G, Fry M, Kirschen M, Abend NS, Ichord R, Nadkarni VM, Berg R, Topjian A. Timing and modes of death after pediatric out-of-hospital cardiac arrest resuscitation. Resuscitation. 2018 12; 133:160-166.

View in: PubMed
Misra I, Glasgow J, Moosavy F. Fat Emboli Syndrome. Del Med J. 2017 May; 89(5):148-150.

View in: PubMed
Bernat JL, Bleck TP, Blosser SA, Bratton SL, Capron AM, Cornell D, DeVita MA, Fulda GJ, Glazier AK, Gries CJ, Mathur M, Nakagawa TA, Shemie SD. Circulatory death determination in uncontrolled organ donors: a panel viewpoint. Ann Emerg Med. 2014 Apr; 63(4):384-90.

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Bernat JL, Capron AM, Bleck TP, Blosser S, Bratton SL, Childress JF, DeVita MA, Fulda GJ, Gries CJ, Mathur M, Nakagawa TA, Rushton CH, Shemie SD, White DB. The circulatory-respiratory determination of death in organ donation. Crit Care Med. 2010 Mar; 38(3):963-70.

View in: PubMed
Doria C. Interleukin-6 plasma level in organ donors influences outcome for recipients of organ transplantation: is it clinically relevant? Crit Care Med. 2008 Jun; 36(6):1971.

View in: PubMed

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