"Buspirone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
Descriptor ID |
D002065
|
MeSH Number(s) |
D02.455.426.779.120 D03.383.606.210 D03.383.742.120 D04.711.120
|
Concept/Terms |
Buspirone- Buspirone
- N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide
|
Below are MeSH descriptors whose meaning is more general than "Buspirone".
Below are MeSH descriptors whose meaning is more specific than "Buspirone".
This graph shows the total number of publications written about "Buspirone" by people in this website by year, and whether "Buspirone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 1 | 2 |
2008 | 1 | 0 | 1 |
2012 | 2 | 0 | 2 |
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Below are the most recent publications written about "Buspirone" by people in Profiles.
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Kline AE, Olsen AS, Sozda CN, Hoffman AN, Cheng JP. Evaluation of a combined treatment paradigm consisting of environmental enrichment and the 5-HT1A receptor agonist buspirone after experimental traumatic brain injury. J Neurotrauma. 2012 Jul 01; 29(10):1960-9.
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Olsen AS, Sozda CN, Cheng JP, Hoffman AN, Kline AE. Traumatic brain injury-induced cognitive and histological deficits are attenuated by delayed and chronic treatment with the 5-HT1A-receptor agonist buspirone. J Neurotrauma. 2012 Jul 01; 29(10):1898-907.
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Elkashef A, Vocci F, Huestis M, Haney M, Budney A, Gruber A, el-Guebaly N. Marijuana neurobiology and treatment. Subst Abus. 2008; 29(3):17-29.
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Zhu M, Zhao W, Vazquez N, Mitroka JG. Analysis of low level radioactive metabolites in biological fluids using high-performance liquid chromatography with microplate scintillation counting: method validation and application. J Pharm Biomed Anal. 2005 Sep 01; 39(1-2):233-45.
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Zhu M, Zhao W, Jimenez H, Zhang D, Yeola S, Dai R, Vachharajani N, Mitroka J. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes. Drug Metab Dispos. 2005 Apr; 33(4):500-7.