"Cardiac Glycosides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
| Descriptor ID |
D002301
|
| MeSH Number(s) |
D04.210.500.155.580 D09.408.180
|
| Concept/Terms |
Cardiac Glycosides- Cardiac Glycosides
- Glycosides, Cardiac
- Cardiotonic Steroids
- Steroids, Cardiotonic
|
Below are MeSH descriptors whose meaning is more general than "Cardiac Glycosides".
Below are MeSH descriptors whose meaning is more specific than "Cardiac Glycosides".
This graph shows the total number of publications written about "Cardiac Glycosides" by people in this website by year, and whether "Cardiac Glycosides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cardiac Glycosides" by people in Profiles.
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Camm AJ, Breithardt G, Crijns H, Dorian P, Kowey P, Le Heuzey JY, Merioua I, Pedrazzini L, Prystowsky EN, Schwartz PJ, Torp-Pedersen C, Weintraub W. Real-life observations of clinical outcomes with rhythm- and rate-control therapies for atrial fibrillation RECORDAF (Registry on Cardiac Rhythm Disorders Assessing the Control of Atrial Fibrillation). J Am Coll Cardiol. 2011 Jul 26; 58(5):493-501.
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Kowey PR, Breithardt G, Camm J, Crijns H, Dorian P, Le Heuzey JY, Pedrazzini L, Prystowsky EN, Salette G, Schwartz PJ, Torp-Pedersen C, Weintraub W. Physician stated atrial fibrillation management in light of treatment guidelines: data from an international, observational prospective survey. Clin Cardiol. 2010 Mar; 33(3):172-8.
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Le Heuzey JY, Breithardt G, Camm J, Crijns H, Dorian P, Kowey PR, Merioua I, Prystowsky EN, Schwartz PJ, Torp-Pedersen C, Weintraub W. The RecordAF study: design, baseline data, and profile of patients according to chosen treatment strategy for atrial fibrillation. Am J Cardiol. 2010 Mar 01; 105(5):687-93.