"Chediak-Higashi Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.
| Descriptor ID |
D002609
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| MeSH Number(s) |
C15.378.553.774.257 C20.673.774.257
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| Concept/Terms |
Chediak-Higashi Syndrome- Chediak-Higashi Syndrome
- Chediak Higashi Syndrome
- Syndrome, Chediak-Higashi
- Oculocutaneous Albinism with Leukocyte Defect
- Chediak-Steinbrinck-Higashi Syndrome
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Below are MeSH descriptors whose meaning is more general than "Chediak-Higashi Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Chediak-Higashi Syndrome".
This graph shows the total number of publications written about "Chediak-Higashi Syndrome" by people in this website by year, and whether "Chediak-Higashi Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chediak-Higashi Syndrome" by people in Profiles.
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Veraitch O, Allison L, Vizcay-Barrena G, Fleck RA, Price A, Fenton DA, McGrath JA, Stefanato CM. Detailed hair shaft analysis in a man with delayed-onset Chediak-Higashi syndrome. Br J Dermatol. 2020 01; 182(1):223-225.
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Gomaa NS, Lee JYW, El Sharkawy A, El Chazli YF, Hassab HMA, Doghaim NN, McGrath JA, Onoufriadis A. Genetic analysis in Egyptian patients with Chediak-Higashi syndrome reveals new LYST mutations. Clin Exp Dermatol. 2019 Oct; 44(7):814-817.