"Chlorpromazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
| Descriptor ID |
D002746
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| MeSH Number(s) |
D02.886.369.198 D03.633.300.741.198
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chlorpromazine".
Below are MeSH descriptors whose meaning is more specific than "Chlorpromazine".
This graph shows the total number of publications written about "Chlorpromazine" by people in this website by year, and whether "Chlorpromazine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chlorpromazine" by people in Profiles.
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Gardecki J, Espinosa J, Lucerna A, Bernhardt J. Singultus: Avoiding a hiccup in care. Am J Emerg Med. 2017 Jun; 35(6):938.e1-938.e3.
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Weisz PB, Kumor K, Macarak EJ. Protection of erythrocytes against hemolytic agents by cyclodextrin polysulfate. Biochem Pharmacol. 1993 Mar 09; 45(5):1011-6.
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Sakaida I, Thomas AP, Farber JL. Phospholipid metabolism and intracellular Ca2+ homeostasis in cultured rat hepatocytes intoxicated with cyanide. Am J Physiol. 1992 Sep; 263(3 Pt 1):C684-90.
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Janoff AS, Mazorow DL, Coughlin RT, Bowdler AJ, Haug A, McGroarty EJ. The modification of human erythrocyte membrane structure by membrane stabilizers: an electron spin resonance study. Am J Hematol. 1981; 10(2):171-9.
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Evans DL, Rogers JF, Peiper SC. Intestinal dilatation associated with phenothiazine therapy: a case report and literature review. Am J Psychiatry. 1979 Jul; 136(7):970-2.
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Janoff AS, Rosenberg B. Chemically evoked hypothermia in the mouse: towards a method for investigating thermodynamic parameters of aging and death in mammals. Mech Ageing Dev. 1978 May; 7(5):335-49.
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Carmichael FJ, Israel Y. In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. J Pharmacol Exp Ther. 1973 Aug; 186(2):253-60.
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Sarin LK, Leopold IH, Winkelman NW. Ocular examinations in outpatients given long-term chlorpromazine therapy. JAMA. 1966 Nov 14; 198(7):789-90.