"Choriocarcinoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
Descriptor ID |
D002822
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MeSH Number(s) |
C04.557.465.955.207 C04.557.470.200.025.455 C04.850.908.208 C13.703.720.949.208
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Choriocarcinoma".
Below are MeSH descriptors whose meaning is more specific than "Choriocarcinoma".
This graph shows the total number of publications written about "Choriocarcinoma" by people in this website by year, and whether "Choriocarcinoma" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1997 | 0 | 1 | 1 |
1998 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 2 | 0 | 2 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Choriocarcinoma" by people in Profiles.
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Hoffman HA, Toshkezi G, Fullmer JM, Hall W, Chin LS. Pitfalls in Diagnosis and Management of Testicular Choriocarcinoma Metastatic to the Brain: Report of 2 Cases and Review of Literature. World Neurosurg. 2017 Oct; 106:536-542.
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Hensley JG, Shviraga BA. Metastastic choriocarcinoma in a term pregnancy: a case study. MCN Am J Matern Child Nurs. 2014 Jan-Feb; 39(1):8-15; quiz 16-7.
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Berghella V, Bamfo J. Editors' choice. BJOG. 2011 Dec; 118(13):i-ii.
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Hanson D, Walter AW, Dunn S, Rittenhouse DW, Griffin G. Infantile choriocarcinoma in a neonate with massive liver involvement cured with chemotherapy and liver transplant. J Pediatr Hematol Oncol. 2011 Aug; 33(6):e258-60.
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Sebire NJ, Fisher RA, Williams S, Prendergast G, Savage P, Seckl M. Indoleamine 2,3-dioxygenase expression in gestational trophoblastic disease: implications for development of immunotherapeutic approaches. J Reprod Med. 2008 Oct; 53(10):789-92.
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Hassanein M, Korant BD, Lu G, Mason RW. Expression of cathepsin P mRNA, protein and activity in the rat choriocarcinoma cell line, Rcho-1, during giant cell transformation. Placenta. 2007 Aug-Sep; 28(8-9):912-9.
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Jondle DM, Shahin MS, Sorosky J, Benda JA. Ovarian mixed germ cell tumor with predominance of polyembryoma: a case report with literature review. Int J Gynecol Pathol. 2002 Jan; 21(1):78-81.
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Pena P, Reutens AT, Albanese C, D'Amico M, Watanabe G, Donner A, Shu IW, Williams T, Pestell RG. Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA. Mol Endocrinol. 1999 Aug; 13(8):1402-16.
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Lazar EL, Stolar CJ. Evaluation and management of pediatric solid ovarian tumors. Semin Pediatr Surg. 1998 02; 7(1):29-34.
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MartĂnez F, Kiriakidou M, Strauss JF. Structural and functional changes in mitochondria associated with trophoblast differentiation: methods to isolate enriched preparations of syncytiotrophoblast mitochondria. Endocrinology. 1997 May; 138(5):2172-83.