"Chromatography, Affinity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chromatographic technique that utilizes the ability of biological molecules to bind to certain ligands specifically and reversibly. It is used in protein biochemistry. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
| Descriptor ID |
D002846
|
| MeSH Number(s) |
E05.196.181.400.170
|
| Concept/Terms |
Chromatography, Affinity- Chromatography, Affinity
- Bioaffinity Chromatography
- Chromatography, Bioaffinity
- Affinity Chromatography
|
Below are MeSH descriptors whose meaning is more general than "Chromatography, Affinity".
Below are MeSH descriptors whose meaning is more specific than "Chromatography, Affinity".
This graph shows the total number of publications written about "Chromatography, Affinity" by people in this website by year, and whether "Chromatography, Affinity" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 4 | 5 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 3 | 4 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chromatography, Affinity" by people in Profiles.
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Tang J, Becker M, Lenhoff A, Chen W. Engineering of heterobifunctional biopolymers for tunable binding and precipitation of Strep-Tag proteins and virus-like nanoparticles. Biotechnol Bioeng. 2024 Dec; 121(12):3860-3868.
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Bhoyar S, Foster M, Oh YH, Xu X, Traylor SJ, Guo J, Ghose S, Lenhoff AM. Engineering protein A ligands to mitigate antibody loss during high-pH washes in protein A chromatography. J Chromatogr A. 2023 May 10; 1696:463962.
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Sripada SA, Chu W, Williams TI, Teten MA, Mosley BJ, Carbonell RG, Lenhoff AM, Cramer SM, Bill J, Yigzaw Y, Roush DJ, Menegatti S. Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents. Biotechnol Bioeng. 2022 07; 119(7):1873-1889.
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Kumar V, Lenhoff AM. Mechanistic Modeling of Preparative Column Chromatography for Biotherapeutics. Annu Rev Chem Biomol Eng. 2020 06 07; 11:235-255.
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Orozco R, Godfrey S, Coffman J, Amarikwa L, Parker S, Hernandez L, Wachuku C, Mai B, Song B, Hoskatti S, Asong J, Shamlou P, Bardliving C, Fiadeiro M. Design, construction, and optimization of a novel, modular, and scalable incubation chamber for continuous viral inactivation. Biotechnol Prog. 2017 Jul; 33(4):954-965.
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Nishida T, Kubota S, Takigawa M. Production of Recombinant CCN2 Protein by Mammalian Cells. Methods Mol Biol. 2017; 1489:95-105.
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Langelier MF, Steffen JD, Riccio AA, McCauley M, Pascal JM. Purification of DNA Damage-Dependent PARPs from E. coli for Structural and Biochemical Analysis. Methods Mol Biol. 2017; 1608:431-444.
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Gu F, Chodavarapu K, McCreary D, Plitt TA, Tamoria E, Ni M, Burnham JJ, Peters M, Lenhoff AM. Silica-based strong anion exchange media for protein purification. J Chromatogr A. 2015 Jan 09; 1376:53-63.
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Levy NE, Valente KN, Choe LH, Lee KH, Lenhoff AM. Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing. Biotechnol Bioeng. 2014 May; 111(5):904-12.
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Liu T, Dean A, Ashwini S, Sheridan PP, Bhushan A, Lai JC, Cao S, Daniels CK. Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells. Cell Stress Chaperones. 2013 Mar; 18(2):223-34.